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Conserved domains on  [gi|109627652|ref|NP_034018|]
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complement factor H precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
19-280 8.30e-25

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 8.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   19 MRLSARIIWLILWTVCAAEDCKGPPPRENSEILS--GSWSEQLYPEGTQATYKCRPGYR--TLGTIVKVCKNGKWVASNP 94
Cdd:PHA02927    1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNsvETDANANYNIGDTIEYLCLPGYRkqKMGPIYAKCTGTGWTLFNQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   95 sriCRKKPCGHPGDTPFGsfRLAVGSqFEFGAKVVYTCDDGYQLLGEI-DYRECGADG---WINDIPLCEVVKCLPVTEL 170
Cdd:PHA02927   81 ---CIKRRCPSPRDIDNG--QLDIGG-VDFGSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  171 ENGRivsgAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSeNGLWSNeKPRCVEILCTPPRVENGD-GINVKPVYKENE 249
Cdd:PHA02927  155 SNGR----HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCS-GGEWSD-PPTCQIVKCPHPTISNGYlSSGFKRSYSYND 228
                         250       260       270
                  ....*....|....*....|....*....|...
gi 109627652  250 RYHYKCKHGYVPKERGDAVCT-GSGWSSQ-PFC 280
Cdd:PHA02927  229 NVDFKCKYGYKLSGSSSSTCSpGNTWQPElPKC 261
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
819-1055 4.73e-24

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 103.19  E-value: 4.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  819 NCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMV--CKDGRWQSLPRCIEKiPCSQPPTIEHGSI 896
Cdd:PHA02927   19 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYakCTGTGWTLFNQCIKR-RCPSPRDIDNGQL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  897 NLprsseerrdsiesSSHEHGTTFSYVCDDGFRIPEENRITCYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLELE 970
Cdd:PHA02927   98 DI-------------GGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYED 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  971 SYQHGEEVTYHCSTGFGIDGPAFIICEGGKWSDPPKCIKTDCDvLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGS 1050
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGS 243

                  ....*
gi 109627652 1051 DTVTC 1055
Cdd:PHA02927  244 SSSTC 248
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
523-762 2.50e-18

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 86.25  E-value: 2.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  523 CIKSC----DMPV---FENSITKNTRTWFKLNDKLDYECLVGFEneyKHTKGSI--TCTYYGWSDTPSCYERECSVP-TL 592
Cdd:PHA02927   16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrDI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  593 DRKLVVSPRKEkyrVGDLLEFSCHSGHRVGPDSVQCYHFG------WSPGFPTCKGqvASCAPPLEILNGEINGAKKVeY 666
Cdd:PHA02927   93 DNGQLDIGGVD---FGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF-Y 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  667 SHGEVVKYDCKPRFLLKGPNKIQCVDGNWTTLPVCieEERTCGDiPELEHGSAKCSVP-PYHHGDSVEFICEENFTMIGH 745
Cdd:PHA02927  167 TDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGS 243
                         250
                  ....*....|....*....
gi 109627652  746 GSVSCISGK-WT-QLPKCV 762
Cdd:PHA02927  244 SSSTCSPGNtWQpELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
949-1187 5.24e-17

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 82.39  E-value: 5.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  949 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPAFIICEGGKWSDPPKCIKTDCDVLPTVKN 1020
Cdd:PHA02927   16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1021 AIIrgkSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-----NSRWIGQ-PVCKDNSCVDPPHVPNATiVTRTKNKYLHGD 1094
Cdd:PHA02927   95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCElgstgSMVWNPEaPICESVKCQSPPSISNGR-HNGYEDFYTDGS 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1095 RVRYECNKPLELFGQVEVMCENGIWTEKPKCRdsTGKCgPPPPIDNGDITSLSLPVYEPLSSVEYQCQKYYLLKGKKTIT 1174
Cdd:PHA02927  171 VVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQ--IVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247
                         250
                  ....*....|....*
gi 109627652 1175 CRNGKWSEP--PTCL 1187
Cdd:PHA02927  248 CSPGNTWQPelPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
292-525 2.97e-14

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.30  E-value: 2.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  292 NGIYTPHRIIHRSDDEIRYECNYGFYPVT-GSTVSKCTPTGWIPVPRCTLKPCEFPQ-FKYGRLYYEeslrpnfPVSIGN 369
Cdd:PHA02927   34 NSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRdIDNGQLDIG-------GVDFGS 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  370 KYSYKCDNGFSpPSGYSWDYLRCTAQG---WEPEVPCVR--KCVF-HYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQnG 443
Cdd:PHA02927  107 SITYSCNSGYQ-LIGESKSYCELGSTGsmvWNPEAPICEsvKCQSpPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI-G 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  444 QDTMTCTENGWSPPPKCIRIKTCSASdihIDNGFLSES-SSIYALNRETSYRCKQGYVTNTgeiSGSITCL-QNGWSPQ- 520
Cdd:PHA02927  185 NSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSG---SSSSTCSpGNTWQPEl 258

                  ....*
gi 109627652  521 PSCIK 525
Cdd:PHA02927  259 PKCVR 263
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
19-280 8.30e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 8.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   19 MRLSARIIWLILWTVCAAEDCKGPPPRENSEILS--GSWSEQLYPEGTQATYKCRPGYR--TLGTIVKVCKNGKWVASNP 94
Cdd:PHA02927    1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNsvETDANANYNIGDTIEYLCLPGYRkqKMGPIYAKCTGTGWTLFNQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   95 sriCRKKPCGHPGDTPFGsfRLAVGSqFEFGAKVVYTCDDGYQLLGEI-DYRECGADG---WINDIPLCEVVKCLPVTEL 170
Cdd:PHA02927   81 ---CIKRRCPSPRDIDNG--QLDIGG-VDFGSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  171 ENGRivsgAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSeNGLWSNeKPRCVEILCTPPRVENGD-GINVKPVYKENE 249
Cdd:PHA02927  155 SNGR----HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCS-GGEWSD-PPTCQIVKCPHPTISNGYlSSGFKRSYSYND 228
                         250       260       270
                  ....*....|....*....|....*....|...
gi 109627652  250 RYHYKCKHGYVPKERGDAVCT-GSGWSSQ-PFC 280
Cdd:PHA02927  229 NVDFKCKYGYKLSGSSSSTCSpGNTWQPElPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
819-1055 4.73e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 103.19  E-value: 4.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  819 NCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMV--CKDGRWQSLPRCIEKiPCSQPPTIEHGSI 896
Cdd:PHA02927   19 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYakCTGTGWTLFNQCIKR-RCPSPRDIDNGQL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  897 NLprsseerrdsiesSSHEHGTTFSYVCDDGFRIPEENRITCYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLELE 970
Cdd:PHA02927   98 DI-------------GGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYED 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  971 SYQHGEEVTYHCSTGFGIDGPAFIICEGGKWSDPPKCIKTDCDvLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGS 1050
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGS 243

                  ....*
gi 109627652 1051 DTVTC 1055
Cdd:PHA02927  244 SSSTC 248
PHA02927 PHA02927
secreted complement-binding protein; Provisional
523-762 2.50e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 86.25  E-value: 2.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  523 CIKSC----DMPV---FENSITKNTRTWFKLNDKLDYECLVGFEneyKHTKGSI--TCTYYGWSDTPSCYERECSVP-TL 592
Cdd:PHA02927   16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrDI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  593 DRKLVVSPRKEkyrVGDLLEFSCHSGHRVGPDSVQCYHFG------WSPGFPTCKGqvASCAPPLEILNGEINGAKKVeY 666
Cdd:PHA02927   93 DNGQLDIGGVD---FGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF-Y 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  667 SHGEVVKYDCKPRFLLKGPNKIQCVDGNWTTLPVCieEERTCGDiPELEHGSAKCSVP-PYHHGDSVEFICEENFTMIGH 745
Cdd:PHA02927  167 TDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGS 243
                         250
                  ....*....|....*....
gi 109627652  746 GSVSCISGK-WT-QLPKCV 762
Cdd:PHA02927  244 SSSTCSPGNtWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
949-1187 5.24e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 82.39  E-value: 5.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  949 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPAFIICEGGKWSDPPKCIKTDCDVLPTVKN 1020
Cdd:PHA02927   16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1021 AIIrgkSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-----NSRWIGQ-PVCKDNSCVDPPHVPNATiVTRTKNKYLHGD 1094
Cdd:PHA02927   95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCElgstgSMVWNPEaPICESVKCQSPPSISNGR-HNGYEDFYTDGS 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1095 RVRYECNKPLELFGQVEVMCENGIWTEKPKCRdsTGKCgPPPPIDNGDITSLSLPVYEPLSSVEYQCQKYYLLKGKKTIT 1174
Cdd:PHA02927  171 VVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQ--IVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247
                         250
                  ....*....|....*
gi 109627652 1175 CRNGKWSEP--PTCL 1187
Cdd:PHA02927  248 CSPGNTWQPelPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
292-525 2.97e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.30  E-value: 2.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  292 NGIYTPHRIIHRSDDEIRYECNYGFYPVT-GSTVSKCTPTGWIPVPRCTLKPCEFPQ-FKYGRLYYEeslrpnfPVSIGN 369
Cdd:PHA02927   34 NSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRdIDNGQLDIG-------GVDFGS 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  370 KYSYKCDNGFSpPSGYSWDYLRCTAQG---WEPEVPCVR--KCVF-HYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQnG 443
Cdd:PHA02927  107 SITYSCNSGYQ-LIGESKSYCELGSTGsmvWNPEAPICEsvKCQSpPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI-G 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  444 QDTMTCTENGWSPPPKCIRIKTCSASdihIDNGFLSES-SSIYALNRETSYRCKQGYVTNTgeiSGSITCL-QNGWSPQ- 520
Cdd:PHA02927  185 NSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSG---SSSSTCSpGNTWQPEl 258

                  ....*
gi 109627652  521 PSCIK 525
Cdd:PHA02927  259 PKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
164-224 4.36e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 4.36e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 109627652  164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCV 224
Cdd:cd00033     1 CPPPPVPENGTVTG----SKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
164-223 4.89e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 4.89e-10
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652    164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRC 223
Cdd:smart00032    1 CPPPPDIENGTVTS----SSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
1132-1186 7.76e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.55  E-value: 7.76e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652 1132 CGPPPPIDNGDITSlSLPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
954-1008 1.24e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.24e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  954 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSD-PPKCI 1008
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
164-223 4.73e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 4.73e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRC 223
Cdd:pfam00084    1 CPPPPDIPNGKVSA----TKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
954-1007 8.78e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 8.78e-09
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    954 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSDP-PKC 1007
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
708-762 9.98e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.47  E-value: 9.98e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  708 CGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCI-SGKWTQ-LPKCV 762
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
708-761 4.59e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 4.59e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    708 CGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCI-SGKWT-QLPKC 761
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
1132-1186 5.98e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 5.98e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   1132 CGPPPPIDNGDITSLSlPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
587-640 2.76e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 2.76e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652   587 CSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHR-VGPDSVQC-YHFGWSPGFPTC 640
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1132-1186 2.34e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 2.34e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  1132 CGPPPPIDNGDITSLSlPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:pfam00084    1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1012-1066 3.82e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.18  E-value: 3.82e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  1012 CDVLPTVKNAIIRGKsKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-NSRWIG-QPVC 1066
Cdd:pfam00084    1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPpFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
412-461 9.18e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.38  E-value: 9.18e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 109627652  412 VENGDSAYWEKVYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 461
Cdd:cd00033     7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
412-460 4.24e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 4.24e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 109627652    412 VENGDSAYWEKVYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 460
Cdd:smart00032    7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
19-280 8.30e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 8.30e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   19 MRLSARIIWLILWTVCAAEDCKGPPPRENSEILS--GSWSEQLYPEGTQATYKCRPGYR--TLGTIVKVCKNGKWVASNP 94
Cdd:PHA02927    1 MKVESVTFLTLLGIGCVLSCCTIPSRPINMKFKNsvETDANANYNIGDTIEYLCLPGYRkqKMGPIYAKCTGTGWTLFNQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   95 sriCRKKPCGHPGDTPFGsfRLAVGSqFEFGAKVVYTCDDGYQLLGEI-DYRECGADG---WINDIPLCEVVKCLPVTEL 170
Cdd:PHA02927   81 ---CIKRRCPSPRDIDNG--QLDIGG-VDFGSSITYSCNSGYQLIGESkSYCELGSTGsmvWNPEAPICESVKCQSPPSI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  171 ENGRivsgAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSeNGLWSNeKPRCVEILCTPPRVENGD-GINVKPVYKENE 249
Cdd:PHA02927  155 SNGR----HNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCS-GGEWSD-PPTCQIVKCPHPTISNGYlSSGFKRSYSYND 228
                         250       260       270
                  ....*....|....*....|....*....|...
gi 109627652  250 RYHYKCKHGYVPKERGDAVCT-GSGWSSQ-PFC 280
Cdd:PHA02927  229 NVDFKCKYGYKLSGSSSSTCSpGNTWQPElPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
819-1055 4.73e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 103.19  E-value: 4.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  819 NCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMV--CKDGRWQSLPRCIEKiPCSQPPTIEHGSI 896
Cdd:PHA02927   19 SCCTIPSRPINMKFKNSVETDANANYNIGDTIEYLCLPGYRKQKMGPIYakCTGTGWTLFNQCIKR-RCPSPRDIDNGQL 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  897 NLprsseerrdsiesSSHEHGTTFSYVCDDGFRIPEENRITCYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLELE 970
Cdd:PHA02927   98 DI-------------GGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYED 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  971 SYQHGEEVTYHCSTGFGIDGPAFIICEGGKWSDPPKCIKTDCDvLPTVKNAIIRGKSKKSYRTGEQVTFRCQSPYQMNGS 1050
Cdd:PHA02927  165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGS 243

                  ....*
gi 109627652 1051 DTVTC 1055
Cdd:PHA02927  244 SSSTC 248
PHA02927 PHA02927
secreted complement-binding protein; Provisional
120-338 2.86e-22

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.80  E-value: 2.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  120 SQFEFGAKVVYTCDDGY--QLLGEIdYRECGADGWiNDIPLCEVVKCLPVTELENGRIVSGAAEtdqeyyFGQVVRFECN 197
Cdd:PHA02927   42 ANYNIGDTIEYLCLPGYrkQKMGPI-YAKCTGTGW-TLFNQCIKRRCPSPRDIDNGQLDIGGVD------FGSSITYSCN 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  198 SGFKIEGHKEIHC----SENGLWSNEKPRCVEILC-TPPRVENGDGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGS 272
Cdd:PHA02927  114 SGYQLIGESKSYCelgsTGSMVWNPEAPICESVKCqSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG 193
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 109627652  273 GWSSQPFCEEKRCSPPYILNG-IYTPHRIIHRSDDEIRYECNYGfYPVTGSTVSKCTP-TGWIP-VPRC 338
Cdd:PHA02927  194 EWSDPPTCQIVKCPHPTISNGyLSSGFKRSYSYNDNVDFKCKYG-YKLSGSSSSTCSPgNTWQPeLPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
523-762 2.50e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 86.25  E-value: 2.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  523 CIKSC----DMPV---FENSITKNTRTWFKLNDKLDYECLVGFEneyKHTKGSI--TCTYYGWSDTPSCYERECSVP-TL 592
Cdd:PHA02927   16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrDI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  593 DRKLVVSPRKEkyrVGDLLEFSCHSGHRVGPDSVQCYHFG------WSPGFPTCKGqvASCAPPLEILNGEINGAKKVeY 666
Cdd:PHA02927   93 DNGQLDIGGVD---FGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF-Y 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  667 SHGEVVKYDCKPRFLLKGPNKIQCVDGNWTTLPVCieEERTCGDiPELEHGSAKCSVP-PYHHGDSVEFICEENFTMIGH 745
Cdd:PHA02927  167 TDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSGS 243
                         250
                  ....*....|....*....
gi 109627652  746 GSVSCISGK-WT-QLPKCV 762
Cdd:PHA02927  244 SSSTCSPGNtWQpELPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
965-1125 4.33e-18

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 85.81  E-value: 4.33e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  965 VSLELESYQHGEEVTYHCSTGFGidgPAFIICEGGKWSDPPKCI-KTDCDVLPTVKNAIIRGKSKKsYRTGEQVTFRCQ- 1042
Cdd:PHA02831   33 DSYENKVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQ-YSFGDSVTYACKv 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1043 ---SPYQMNGSDTVTCVNSRWIGQ-PVCKDNSCvDPPHVPNAtIVTRTKNKYLHGDRVRYECNKPLELFGQVEVMCE-NG 1117
Cdd:PHA02831  109 nklEKYSIVGNETVKCINKQWVPKyPVCKLIRC-KYPALQNG-FLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDiNS 186

                  ....*....
gi 109627652 1118 IWTEK-PKC 1125
Cdd:PHA02831  187 IWYPGiPKC 195
PHA02927 PHA02927
secreted complement-binding protein; Provisional
949-1187 5.24e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 82.39  E-value: 5.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  949 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPAFIICEGGKWSDPPKCIKTDCDVLPTVKN 1020
Cdd:PHA02927   16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1021 AIIrgkSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-----NSRWIGQ-PVCKDNSCVDPPHVPNATiVTRTKNKYLHGD 1094
Cdd:PHA02927   95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCElgstgSMVWNPEaPICESVKCQSPPSISNGR-HNGYEDFYTDGS 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1095 RVRYECNKPLELFGQVEVMCENGIWTEKPKCRdsTGKCgPPPPIDNGDITSLSLPVYEPLSSVEYQCQKYYLLKGKKTIT 1174
Cdd:PHA02927  171 VVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQ--IVKC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247
                         250
                  ....*....|....*
gi 109627652 1175 CRNGKWSEP--PTCL 1187
Cdd:PHA02927  248 CSPGNTWQPelPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
292-525 2.97e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 74.30  E-value: 2.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  292 NGIYTPHRIIHRSDDEIRYECNYGFYPVT-GSTVSKCTPTGWIPVPRCTLKPCEFPQ-FKYGRLYYEeslrpnfPVSIGN 369
Cdd:PHA02927   34 NSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRdIDNGQLDIG-------GVDFGS 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  370 KYSYKCDNGFSpPSGYSWDYLRCTAQG---WEPEVPCVR--KCVF-HYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQnG 443
Cdd:PHA02927  107 SITYSCNSGYQ-LIGESKSYCELGSTGsmvWNPEAPICEsvKCQSpPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI-G 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  444 QDTMTCTENGWSPPPKCIRIKTCSASdihIDNGFLSES-SSIYALNRETSYRCKQGYVTNTgeiSGSITCL-QNGWSPQ- 520
Cdd:PHA02927  185 NSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSG---SSSSTCSpGNTWQPEl 258

                  ....*
gi 109627652  521 PSCIK 525
Cdd:PHA02927  259 PKCVR 263
PHA02831 PHA02831
EEV host range protein; Provisional
907-1073 3.51e-14

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 74.26  E-value: 3.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  907 DSIESSSHEHGTTFSYVCDDGFripEENRITCYMGKWSTPPRCVG-LPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG 985
Cdd:PHA02831   33 DSYENKVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGkRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVN 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  986 ----FGIDGPAFIICEGGKW-SDPPKCIKTDCDvLPTVKNAIIRGKSKKSYrTGEQVTFRCQSPYQMNGSDTVTC-VNSR 1059
Cdd:PHA02831  110 klekYSIVGNETVKCINKQWvPKYPVCKLIRCK-YPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCdINSI 187
                         170
                  ....*....|....*
gi 109627652 1060 WI-GQPVCKDNSCVD 1073
Cdd:PHA02831  188 WYpGIPKCVKDKVHN 202
PHA02927 PHA02927
secreted complement-binding protein; Provisional
30-224 6.10e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 73.53  E-value: 6.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   30 LWTVCAAEDCKGPPPRENSEILSGSwseqlYPEGTQATYKCRPGYRTLGTIVKVCK---NGKWVASNPSRICRKKPCGHP 106
Cdd:PHA02927   77 LFNQCIKRRCPSPRDIDNGQLDIGG-----VDFGSSITYSCNSGYQLIGESKSYCElgsTGSMVWNPEAPICESVKCQSP 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  107 GDTPFGSFRlAVGSQFEFGAKVVYTCDDGYQLLGEIDYReCGADGWiNDIPLCEVVKClPVTELENGRIVSGAAETdqeY 186
Cdd:PHA02927  152 PSISNGRHN-GYEDFYTDGSVVTYSCNSGYSLIGNSGVL-CSGGEW-SDPPTCQIVKC-PHPTISNGYLSSGFKRS---Y 224
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 109627652  187 YFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCV 224
Cdd:PHA02927  225 SYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
1030-1228 1.20e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.38  E-value: 1.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1030 SYRTGEQVTFRCQSPY--QMNGSDTVTCVNSRWIGQPVCKDNSCVDPPHVPNATIVTRTKNkylHGDRVRYECNKPLELF 1107
Cdd:PHA02927   43 NYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDNGQLDIGGVD---FGSSITYSCNSGYQLI 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1108 GQVEVMCENG-----IWT-EKPKCRdsTGKCGPPPPIDNGDITSLSlPVYEPLSSVEYQCQKYYLLKGKKTITCRNGKWS 1181
Cdd:PHA02927  120 GESKSYCELGstgsmVWNpEAPICE--SVKCQSPPSISNGRHNGYE-DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWS 196
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 109627652 1182 EPPTClHACVIPENIMESHNIILKWRHTekiYSHSgEDIEFGCKYGY 1228
Cdd:PHA02927  197 DPPTC-QIVKCPHPTISNGYLSSGFKRS---YSYN-DNVDFKCKYGY 238
PHA02831 PHA02831
EEV host range protein; Provisional
54-225 3.44e-13

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 71.18  E-value: 3.44e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   54 SWSEQLYPEGTQATYKCRPGYrtlGTIVKVCKNGKWVASNpsrIC-RKKPCGHPGDTPFGSFRlAVGSQFEFGAKVVYTC 132
Cdd:PHA02831   34 SYENKVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKN---MCiGKRNCKDPVTILNGYIK-NKKDQYSFGDSVTYAC 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  133 D----DGYQLLGEiDYRECGADGWINDIPLCEVVKClPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEI 208
Cdd:PHA02831  107 KvnklEKYSIVGN-ETVKCINKQWVPKYPVCKLIRC-KYPALQNGFLNV----FEKKFYYGDIVNFKCKKGFILLGSSVS 180
                         170
                  ....*....|....*..
gi 109627652  209 HCSENGLWSNEKPRCVE 225
Cdd:PHA02831  181 TCDINSIWYPGIPKCVK 197
PHA02927 PHA02927
secreted complement-binding protein; Provisional
605-820 1.13e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 69.68  E-value: 1.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  605 YRVGDLLEFSCHSGHR---VGPDSVQCYHFGWSPgFPTCKGQvaSCAPPLEILNGEINgAKKVEYshGEVVKYDCKPRFL 681
Cdd:PHA02927   44 YNIGDTIEYLCLPGYRkqkMGPIYAKCTGTGWTL-FNQCIKR--RCPSPRDIDNGQLD-IGGVDF--GSSITYSCNSGYQ 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  682 LKGPNKIQCVDGNWTTL------PVCieEERTCGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCISGKW 755
Cdd:PHA02927  118 LIGESKSYCELGSTGSMvwnpeaPIC--ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  756 TQLPKCvatdQLEKCRVLKSTGIEAIKPKLTEFTHNSTMDYKCRDKQEY---ERSICINGK-WDPE-PNC 820
Cdd:PHA02927  196 SDPPTC----QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsgsSSSTCSPGNtWQPElPKC 261
PHA02831 PHA02831
EEV host range protein; Provisional
532-705 1.78e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 69.25  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  532 FENSITKNTRTwFKLNDKLDYECLVGFENEYkhtkgsITCTYYGWSDTPSCY-ERECSVPTLDRKLVVSPRKEKYRVGDL 610
Cdd:PHA02831   29 YSNVDSYENKV-YEENENLEYKCNNNFDKVF------VTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQYSFGDS 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  611 LEFSCHSGHR-----VGPDSVQCYHFGWSPGFPTCKgqVASCAPPlEILNGEINGAKKvEYSHGEVVKYDCKPRFLLKGP 685
Cdd:PHA02831  102 VTYACKVNKLekysiVGNETVKCINKQWVPKYPVCK--LIRCKYP-ALQNGFLNVFEK-KFYYGDIVNFKCKKGFILLGS 177
                         170       180
                  ....*....|....*....|..
gi 109627652  686 NKIQC-VDGNWT-TLPVCIEEE 705
Cdd:PHA02831  178 SVSTCdINSIWYpGIPKCVKDK 199
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
830-1074 2.13e-12

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 69.73  E-value: 2.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  830 PQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEmVCKDGRWQSlprcieKIPCSQPPTIehgsinlprsSEERRDSI 909
Cdd:PHA02954   24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNA-VCETDKWKY------ENPCKKMCTV----------SDYVSELY 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  910 ESSSHEHGTTFSYVCDDG---FRIPEENRITcymgKWSTPPRCVGLPCgPPPSIPLGTVSLELESYQHGEEVTYHCSTGF 986
Cdd:PHA02954   87 DKPLYEVNSTITLICKDEtkyFRCEEKNGNT----SWNDTVTCPNAEC-QPLQLEHGSCQPVKEKYSFGEHITINCDVGY 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  987 GIDGPAFIICEGGKWSDPPKCiKTDCDvLPTVKNAIIRGkskKSYRTGEQVTFRCQSPYQMNGSDTVTCVNSRWIG-QPV 1065
Cdd:PHA02954  162 EVIGASYISCTANSWNVIPSC-QQKCD-IPSLSNGLISG---STFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPvLPI 236
                         250
                  ....*....|
gi 109627652 1066 C-KDNSCVDP 1074
Cdd:PHA02954  237 CvRSNEEFDP 246
PHA02831 PHA02831
EEV host range protein; Provisional
597-762 2.06e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.78  E-value: 2.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  597 VVSPRKEKYRVGDLLEFSCHSGHrvgpDSV--QCYHFGWSPGfPTCKGQvASCAPPLEILNGEINGaKKVEYSHGEVVKY 674
Cdd:PHA02831   32 VDSYENKVYEENENLEYKCNNNF----DKVfvTCNNGSWSTK-NMCIGK-RNCKDPVTILNGYIKN-KKDQYSFGDSVTY 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  675 DCK----PRFLLKGPNKIQCVDGNWT-TLPVCieEERTCgDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVS 749
Cdd:PHA02831  105 ACKvnklEKYSIVGNETVKCINKQWVpKYPVC--KLIRC-KYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVST 181
                         170
                  ....*....|....*
gi 109627652  750 C-ISGKWT-QLPKCV 762
Cdd:PHA02831  182 CdINSIWYpGIPKCV 196
PHA02927 PHA02927
secreted complement-binding protein; Provisional
413-640 1.48e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 63.13  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  413 ENGDSAYWEKVYVQGQSLKVQCYNGYSLQN-GQDTMTCTENGWSPPPKCIRIKTCSASDI---HIDNGFLSESSSI---- 484
Cdd:PHA02927   33 KNSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIdngQLDIGGVDFGSSItysc 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  485 ---YALNRETSYRCKQGYvtntgeiSGSITclqngWSPQ-PSC--IKSCDMPVFENSITKNTRTWFKLNDKLDYECLVGF 558
Cdd:PHA02927  113 nsgYQLIGESKSYCELGS-------TGSMV-----WNPEaPICesVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGY 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  559 EneyKHTKGSITCTYYGWSDTPSCYERECSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHRV-GPDSVQCYHFG-WSPG 636
Cdd:PHA02927  181 S---LIGNSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsGSSSSTCSPGNtWQPE 257

                  ....
gi 109627652  637 FPTC 640
Cdd:PHA02927  258 LPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
914-1073 3.01e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 62.76  E-value: 3.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  914 HEHGTTFSYVCDDGFRIPEENRITCYMGK----WST-PPRCVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGI 988
Cdd:PHA02639   40 YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNkAPFCMLKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHKGV 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  989 D----GPAFIICEGGK-WS-DPPKCIKTDCDvLPTVKNAIIRG-KSKKSYRTGEQVTFRCQSPYQMNGSDTVTC-VNSRW 1060
Cdd:PHA02639  120 QyslvGNEKITCIQDKsWKpDPPICKMINCR-FPALQNGYINGiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCnINATW 198
                         170
                  ....*....|....
gi 109627652 1061 IGQ-PVCKDNSCVD 1073
Cdd:PHA02639  199 FPSiPTCVRNKPID 212
PHA02639 PHA02639
EEV host range protein; Provisional
103-268 3.85e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 62.37  E-value: 3.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  103 CGHPGDTPFGsFRLAVGSQFEFGAKVVYTCDDGYQLLGEiDYRECGADG----WINDIPLCEVVKCLPVTELENGRIVSg 178
Cdd:PHA02639   22 CDKPDDISNG-FITELMEKYEIGKLIEYTCNTDYALIGD-RFRTCIKDKnnaiWSNKAPFCMLKECNDPPSIINGKIYN- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  179 aaeTDQEYYFGQVVRFECNS----GFKIEGHKEIHCSENGLWSNEKPRCVEILCTPPRVENGdGINVKPvykENERYHYK 254
Cdd:PHA02639   99 ---KREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPALQNG-YINGIP---SNKKFYYK 171
                         170
                  ....*....|....
gi 109627652  255 CKHGYVPKERGDAV 268
Cdd:PHA02639  172 TRVGFSCKSGFDLV 185
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
164-224 4.36e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.32  E-value: 4.36e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 109627652  164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCV 224
Cdd:cd00033     1 CPPPPVPENGTVTG----SKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
164-223 4.89e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 4.89e-10
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652    164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRC 223
Cdd:smart00032    1 CPPPPDIENGTVTS----SSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
244-414 5.59e-10

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 61.55  E-value: 5.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  244 VYKENERYHYKCKHGYvpkERGDAVCTGSGWSSQPFCEEKR-CSPPY-ILNGIYTPHRIIHRSDDEIRYECNYG---FYP 318
Cdd:PHA02831   39 VYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGKRnCKDPVtILNGYIKNKKDQYSFGDSVTYACKVNkleKYS 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  319 VTGSTVSKCTPTGWIP-VPRCTLKPCEFPQFKYGRLyyeESLRPNFpvSIGNKYSYKCDNGF----SPPSGYSWDYLrct 393
Cdd:PHA02831  116 IVGNETVKCINKQWVPkYPVCKLIRCKYPALQNGFL---NVFEKKF--YYGDIVNFKCKKGFillgSSVSTCDINSI--- 187
                         170       180
                  ....*....|....*....|.
gi 109627652  394 aqgWEPEVPcvrKCVFHYVEN 414
Cdd:PHA02831  188 ---WYPGIP---KCVKDKVHN 202
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
1132-1186 7.76e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.55  E-value: 7.76e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652 1132 CGPPPPIDNGDITSlSLPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
954-1008 1.24e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 1.24e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  954 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSD-PPKCI 1008
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
24-224 2.59e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 60.06  E-value: 2.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   24 RIIWLILWTVCAAEDCKGPPPRENSEILSGSWSEQL--YPEGTQATYKCRPGYRTLGTIVKVCKNGK--WVASNPSRICR 99
Cdd:PHA02639    2 KIILYLFIGVCYVHGVKSIYCDKPDDISNGFITELMekYEIGKLIEYTCNTDYALIGDRFRTCIKDKnnAIWSNKAPFCM 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  100 KKPCGHPGDTPFGSFrLAVGSQFEFGAKVVYTCDD----GYQLLGEIDYRECGADGWINDIPLCEVVKClPVTELENGRI 175
Cdd:PHA02639   82 LKECNDPPSIINGKI-YNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINC-RFPALQNGYI 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 109627652  176 vsGAAETDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRCV 224
Cdd:PHA02639  160 --NGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
Sushi pfam00084
Sushi repeat (SCR repeat);
164-223 4.73e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 4.73e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   164 CLPVTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIHCSENGLWSNEKPRC 223
Cdd:pfam00084    1 CPPPPDIPNGKVSA----TKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
726-950 5.04e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.51  E-value: 5.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  726 YHHGDSVEFICEENFTMIGHGSV--SCISGKWTQLPKCVAtdqlEKCRVLKSTGIEAIKPKLTEFthNSTMDYKCRDKQE 803
Cdd:PHA02927   44 YNIGDTIEYLCLPGYRKQKMGPIyaKCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  804 Y---ERSICINGK-----WDPEPNCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMVCKDGRWQS 875
Cdd:PHA02927  118 LigeSKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652  876 LPRC-IEKIPcsqPPTIEHGSInlprSSEERRdsiessSHEHGTTFSYVCDDGFRIPEENRITCYMGKWSTP--PRCV 950
Cdd:PHA02927  198 PPTCqIVKCP---HPTISNGYL----SSGFKR------SYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
954-1007 8.78e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 8.78e-09
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    954 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSDP-PKC 1007
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
708-762 9.98e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.47  E-value: 9.98e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  708 CGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCI-SGKWTQ-LPKCV 762
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
708-761 4.59e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 4.59e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    708 CGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCI-SGKWT-QLPKC 761
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
1132-1186 5.98e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 5.98e-08
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   1132 CGPPPPIDNGDITSLSlPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:smart00032    1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
647-702 1.10e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.77  E-value: 1.10e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652  647 CAPPLEILNGEINGAKKvEYSHGEVVKYDCKPRFLLKGPNKIQCV-DGNWT-TLPVCI 702
Cdd:cd00033     1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
934-1069 1.58e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 53.79  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  934 NRITCYmgkwstpprCVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG-----FGIDGPAFIICE-GGKWS-DPPK 1006
Cdd:PHA02817   13 NKVYSL---------CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNkEFPV 83
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652 1007 CIKTDCDvLPTVKNAIIRG-KSKKSYRTGEQVTFRCQSPYQMNGSDTVTC-VNSRWIGQ-PVCKDN 1069
Cdd:PHA02817   84 CKIIRCR-FPALQNGFVNGiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPKvPICSRD 148
PHA02639 PHA02639
EEV host range protein; Provisional
230-405 1.81e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 54.28  E-value: 1.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  230 PPRVENGDGINVKPVYKENERYHYKCKHGYV---------PKERGDAVctgsgWSSQ-PFCEEKRCS-PPYILNGIYTPH 298
Cdd:PHA02639   25 PDDISNGFITELMEKYEIGKLIEYTCNTDYAligdrfrtcIKDKNNAI-----WSNKaPFCMLKECNdPPSIINGKIYNK 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  299 RIIHRSDDEIRYECNYGF---YPVTGSTVSKCTP-TGWIPVPR-CTLKPCEFPQFKYGrlyYEESLRPNfpvsigNKYSY 373
Cdd:PHA02639  100 REMYKVGDEIYYVCNEHKgvqYSLVGNEKITCIQdKSWKPDPPiCKMINCRFPALQNG---YINGIPSN------KKFYY 170
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 109627652  374 KCDNGFSPPSGYSW---DYLRCTAQG-WEPEVP-CVR 405
Cdd:PHA02639  171 KTRVGFSCKSGFDLvgeKYSTCNINAtWFPSIPtCVR 207
Sushi pfam00084
Sushi repeat (SCR repeat);
587-640 2.76e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 2.76e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652   587 CSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHR-VGPDSVQC-YHFGWSPGFPTC 640
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
1071-1126 6.81e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.46  E-value: 6.81e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652 1071 CVDPPHVPNATIVTRtKNKYLHGDRVRYECNKPLELFGQVEVMC-ENGIWT-EKPKCR 1126
Cdd:cd00033     1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
418-558 6.94e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 52.30  E-value: 6.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  418 AYWEKVYVQGQSLKVQCYNGYSlqngQDTMTCTENGWSPPPKCIRIKTCSaSDIHIDNGFLSESSSIYALNRETSYRCKQ 497
Cdd:PHA02831   34 SYENKVYEENENLEYKCNNNFD----KVFVTCNNGSWSTKNMCIGKRNCK-DPVTILNGYIKNKKDQYSFGDSVTYACKV 108
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 109627652  498 GYVTNTGEISG-SITCLQNGWSPQ-PSC-IKSCDMPVFENSITKNTRTWFKLNDKLDYECLVGF 558
Cdd:PHA02831  109 NKLEKYSIVGNeTVKCINKQWVPKyPVCkLIRCKYPALQNGFLNVFEKKFYYGDIVNFKCKKGF 172
PHA02639 PHA02639
EEV host range protein; Provisional
473-640 7.73e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 52.36  E-value: 7.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  473 IDNGFLSESSSIYALNRETSYRCKQGYVTNTGEISGSITCLQNG-WSPQ-PSC-IKSC-DMPVFENSITKNTRTWFKLND 548
Cdd:PHA02639   28 ISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKaPFCmLKECnDPPSIINGKIYNKREMYKVGD 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  549 KLDYEClvgfeNEYKHTKGS------ITCTY-YGWS-DTPSCYERECSVPTLDRKLVVS-PRKEKYRVGDLLEFSCHSGH 619
Cdd:PHA02639  108 EIYYVC-----NEHKGVQYSlvgnekITCIQdKSWKpDPPICKMINCRFPALQNGYINGiPSNKKFYYKTRVGFSCKSGF 182
                         170       180
                  ....*....|....*....|...
gi 109627652  620 R-VGPDSVQC-YHFGWSPGFPTC 640
Cdd:PHA02639  183 DlVGEKYSTCnINATWFPSIPTC 205
PHA02831 PHA02831
EEV host range protein; Provisional
788-950 9.52e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 51.92  E-value: 9.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  788 FTHNSTMDYKCRDKQEYERSICINGKWDPEPNCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDS---- 863
Cdd:PHA02831   40 YEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKYSivgn 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  864 EEMVCKDGRW-QSLPRCiEKIPCSQpPTIEHGSINlprsseerrdSIESSSHeHGTTFSYVCDDGFRIPEENRITCYMGK 942
Cdd:PHA02831  120 ETVKCINKQWvPKYPVC-KLIRCKY-PALQNGFLN----------VFEKKFY-YGDIVNFKCKKGFILLGSSVSTCDINS 186
                         170
                  ....*....|
gi 109627652  943 WSTP--PRCV 950
Cdd:PHA02831  187 IWYPgiPKCV 196
PHA02639 PHA02639
EEV host range protein; Provisional
1012-1187 1.45e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 51.59  E-value: 1.45e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1012 CDVLPTVKNAIIRGKSKKsYRTGEQVTFRCQSPYQMNGSDTVTCV----NSRWIGQ-PVCKDNSCVDPPHVPNATIVTRt 1086
Cdd:PHA02639   22 CDKPDDISNGFITELMEK-YEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNKaPFCMLKECNDPPSIINGKIYNK- 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1087 KNKYLHGDRVRYECNK----PLELFGQVEVMC-ENGIWT-EKPKCRDSTGKCgppPPIDNGDITSL-SLPVYEPLSSVEY 1159
Cdd:PHA02639  100 REMYKVGDEIYYVCNEhkgvQYSLVGNEKITCiQDKSWKpDPPICKMINCRF---PALQNGYINGIpSNKKFYYKTRVGF 176
                         170       180       190
                  ....*....|....*....|....*....|
gi 109627652 1160 QCQKYYLLKGKKTITCR-NGKW-SEPPTCL 1187
Cdd:PHA02639  177 SCKSGFDLVGEKYSTCNiNATWfPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
1012-1067 1.78e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.30  E-value: 1.78e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652 1012 CDVLPTVKNAIIRGkSKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-NSRWIG-QPVCK 1067
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
1132-1186 2.34e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 2.34e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  1132 CGPPPPIDNGDITSLSlPVYEPLSSVEYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 1186
Cdd:pfam00084    1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
647-701 3.11e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.60  E-value: 3.11e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652    647 CAPPLEILNGEINGAKKvEYSHGEVVKYDCKPRFLLKGPNKIQCV-DGNWT-TLPVC 701
Cdd:smart00032    1 CPPPPDIENGTVTSSSG-TYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
1012-1066 3.82e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.18  E-value: 3.82e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  1012 CDVLPTVKNAIIRGKsKKSYRTGEQVTFRCQSPYQMNGSDTVTCV-NSRWIG-QPVC 1066
Cdd:pfam00084    1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPpFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
103-160 3.91e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 3.91e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 109627652  103 CGHPGDTPFGSFRLAVGSqFEFGAKVVYTCDDGYQLLGEiDYRECGADG-WINDIPLCE 160
Cdd:cd00033     1 CPPPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGS-STITCTENGgWSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
1090-1228 4.43e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 49.61  E-value: 4.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1090 YLHGDRVRYECNKPlelFGQVEVMCENGIWTEKPKCRDSTgKCGPPPPIDNGDITSlSLPVYEPLSSVEYQCQ----KYY 1165
Cdd:PHA02831   40 YEENENLEYKCNNN---FDKVFVTCNNGSWSTKNMCIGKR-NCKDPVTILNGYIKN-KKDQYSFGDSVTYACKvnklEKY 114
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652 1166 LLKGKKTITCRNGKW-SEPPTC-LHACVIP---ENIMESHNiilkwrhtEKIYshSGEDIEFGCKYGY 1228
Cdd:PHA02831  115 SIVGNETVKCINKQWvPKYPVCkLIRCKYPalqNGFLNVFE--------KKFY--YGDIVNFKCKKGF 172
PHA02817 PHA02817
EEV Host range protein; Provisional
581-711 5.31e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 5.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  581 SCYERECSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHR------VGPDSVQCYHFG-WSPGFPTCKgqVASCAPPlEI 653
Cdd:PHA02817   18 LCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRgvrytlVGEKNIICEKDGkWNKEFPVCK--IIRCRFP-AL 94
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 109627652  654 LNGEING---AKKVEYShgEVVKYDCKPRFLLKG-PNKIQCVDGNW-TTLPVCIEEERTCGDI 711
Cdd:PHA02817   95 QNGFVNGipdSKKFYYE--SEVSFSCKPGFVLIGtKYSVCGINSSWiPKVPICSRDNITYNKI 155
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
1071-1125 5.89e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 5.89e-06
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   1071 CVDPPHVPNATIVTrTKNKYLHGDRVRYECNKPLELFGQVEVMC-ENGIWT-EKPKC 1125
Cdd:smart00032    1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
885-950 7.04e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.38  E-value: 7.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652  885 CSQPPTIEHGSInlprsseerrdSIESSSHEHGTTFSYVCDDGFRIPEENRITCYM-GKWS-TPPRCV 950
Cdd:cd00033     1 CPPPPVPENGTV-----------TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
885-949 7.46e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.44  E-value: 7.46e-06
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652    885 CSQPPTIEHGSINLPrsseerrdsieSSSHEHGTTFSYVCDDGFRIPEENRITCYM-GKWS-TPPRC 949
Cdd:smart00032    1 CPPPPDIENGTVTSS-----------SGTYSYGDTVTYSCDPGYTLIGSSTITCLEnGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
412-461 9.18e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.38  E-value: 9.18e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 109627652  412 VENGDSAYWEKVYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 461
Cdd:cd00033     7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
587-641 9.73e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 9.73e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  587 CSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHR-VGPDSVQCY-HFGWSPGFPTCK 641
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTlVGSSTITCTeNGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
1012-1066 1.06e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.05  E-value: 1.06e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   1012 CDVLPTVKNAIIRGkSKKSYRTGEQVTFRCQSPYQMNGSDTVTCVNS-RWIG-QPVC 1066
Cdd:smart00032    1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGSSTITCLENgTWSPpPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
407-640 1.45e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 48.54  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  407 CVFHYVENGDSAYWEKVYVQGQSLKVQCYNGYslQNGQDTMTCTENGWSPPPKCIRIKTCSASDIHIDNGFLSESSSIYA 486
Cdd:PHA02954   21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGY--YSLDPNAVCETDKWKYENPCKKMCTVSDYVSELYDKPLYEVNSTIT 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  487 L--NRETSY-RCKQgyvtNTGEISgsitclqngWSPQPSCIKS-CDMPVFENSITKNTRTWFKLNDKLDYECLVGFEney 562
Cdd:PHA02954   99 LicKDETKYfRCEE----KNGNTS---------WNDTVTCPNAeCQPLQLEHGSCQPVKEKYSFGEHITINCDVGYE--- 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 109627652  563 KHTKGSITCTYYGWSDTPSCyERECSVPTLDRKLVVSprkEKYRVGDLLEFSCHSGHRV-GPDSVQCYHFGWSPGFPTC 640
Cdd:PHA02954  163 VIGASYISCTANSWNVIPSC-QQKCDIPSLSNGLISG---STFSIGGVIHLSCKSGFTLtGSPSSTCIDGKWNPVLPIC 237
Sushi pfam00084
Sushi repeat (SCR repeat);
1071-1125 1.45e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 1.45e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  1071 CVDPPHVPNAtIVTRTKNKYLHGDRVRYECNKPLELFGQVEVMC-ENGIWT-EKPKC 1125
Cdd:pfam00084    1 CPPPPDIPNG-KVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
120-225 1.65e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 47.63  E-value: 1.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  120 SQFEFGAKVVYTCDDG-----YQLLGEiDYRECGADG-WINDIPLCEVVKC-LPVteLENGrIVSGAAETdQEYYFGQVV 192
Cdd:PHA02817   40 TEYNIGSNVTFFCGNNtrgvrYTLVGE-KNIICEKDGkWNKEFPVCKIIRCrFPA--LQNG-FVNGIPDS-KKFYYESEV 114
                          90       100       110
                  ....*....|....*....|....*....|...
gi 109627652  193 RFECNSGFKIEGHKEIHCSENGLWSNEKPRCVE 225
Cdd:PHA02817  115 SFSCKPGFVLIGTKYSVCGINSSWIPKVPICSR 147
PHA02639 PHA02639
EEV host range protein; Provisional
603-774 1.92e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 48.12  E-value: 1.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  603 EKYRVGDLLEFSCHSGHRVGPDSVQC-----YHFGWSPGFPTCkgQVASCAPPLEILNGEINGAKKVeYSHGEVVKYDCK 677
Cdd:PHA02639   38 EKYEIGKLIEYTCNTDYALIGDRFRTcikdkNNAIWSNKAPFC--MLKECNDPPSIINGKIYNKREM-YKVGDEIYYVCN 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  678 P----RFLLKGPNKIQCV-DGNWT-TLPVCieeERTCGDIPELEHG--SAKCSVPPYHHGDSVEFICEENFTMIGHGSVS 749
Cdd:PHA02639  115 EhkgvQYSLVGNEKITCIqDKSWKpDPPIC---KMINCRFPALQNGyiNGIPSNKKFYYKTRVGFSCKSGFDLVGEKYST 191
                         170       180
                  ....*....|....*....|....*..
gi 109627652  750 C-ISGKW-TQLPKCVATDQLEKCRVLK 774
Cdd:PHA02639  192 CnINATWfPSIPTCVRNKPIDDIIYLK 218
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
221-462 2.59e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 47.77  E-value: 2.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  221 PRCVEILCTPPRVENGDGINVKPVYKENERYHYKCKHGYVPKERgDAVCTGSGWSSQPFCeEKRCSPPYILNGIYtpHRI 300
Cdd:PHA02954   14 PAVVYSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDP-NAVCETDKWKYENPC-KKMCTVSDYVSELY--DKP 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  301 IHRSDDEIRYECNygfypvTGSTVSKCTP----TGWIPVPRCTLKPCEFPQFKYGrlyyeeSLRP-NFPVSIGNKYSYKC 375
Cdd:PHA02954   90 LYEVNSTITLICK------DETKYFRCEEkngnTSWNDTVTCPNAECQPLQLEHG------SCQPvKEKYSFGEHITINC 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  376 DNGFSPPSGyswDYLRCTAQGWEPEVPCVRKCVFHYVENGDSAywEKVYVQGQSLKVQCYNGYSLqNGQDTMTCTENGWS 455
Cdd:PHA02954  158 DVGYEVIGA---SYISCTANSWNVIPSCQQKCDIPSLSNGLIS--GSTFSIGGVIHLSCKSGFTL-TGSPSSTCIDGKWN 231

                  ....*...
gi 109627652  456 PP-PKCIR 462
Cdd:PHA02954  232 PVlPICVR 239
Sushi pfam00084
Sushi repeat (SCR repeat);
954-1007 2.98e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 2.98e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652   954 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPAFIIC-EGGKWSDP-PKC 1007
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
826-880 3.63e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 42.45  E-value: 3.63e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  826 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMVC-KDGRW-QSLPRCI 880
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWsPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
103-159 3.66e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 3.66e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652    103 CGHPGDTPFGSFRLaVGSQFEFGAKVVYTCDDGYQLLGEiDYRECGADG-WINDIPLC 159
Cdd:smart00032    1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPGYTLIGS-STITCLENGtWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
647-701 3.96e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 3.96e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   647 CAPPLEILNGEINGaKKVEYSHGEVVKYDCKPRFLLKGPNKIQCV-DGNWT-TLPVC 701
Cdd:pfam00084    1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
412-460 4.24e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 4.24e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|.
gi 109627652    412 VENGDSAYWEKVYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 460
Cdd:smart00032    7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
159-280 4.35e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.09  E-value: 4.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  159 CEVVKCLPVTELENGRIVsgaaETDQEYYFGQVVRFECNSG-----FKIEGHKEIHCSENGLWSNEKPRCVEILCTPPRV 233
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIY----NKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPAL 94
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 109627652  234 ENG--DGINVKPVYKENERYHYKCKHGYVPKERGDAVC-TGSGWSSQ-PFC 280
Cdd:PHA02817   95 QNGfvNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWIPKvPIC 145
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
587-640 4.41e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.13  E-value: 4.41e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    587 CSVPTLDRKLVVSPRKEKYRVGDLLEFSCHSGHR-VGPDSVQCYHFG-WSPGFPTC 640
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTlIGSSTITCLENGtWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
167-405 1.16e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.85  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  167 VTELENGRIVSgaaeTDQEYYFGQVVRFECNSGFKIEGHKEIhcSENGLWSNEKPrCVEILCTPPRVENgdgINVKPVYK 246
Cdd:PHA02954   23 VPTMNNAKLTS----TETSFNDKQKVTFTCDSGYYSLDPNAV--CETDKWKYENP-CKKMCTVSDYVSE---LYDKPLYE 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  247 ENERYHYKCKhGYVPKERGDAVCTGSGWSSQPFCEEKRCSPPYILNGIYTPHRIIHRSDDEIRYECNYGfYPVTGSTVSK 326
Cdd:PHA02954   93 VNSTITLICK-DETKYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVG-YEVIGASYIS 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  327 CTPTGWIPVPRCTLKpCEFPQFKYGrlyyeesLRPNFPVSIGNKYSYKCDNGF----SPPSgyswdylRCTAQGWEPEVP 402
Cdd:PHA02954  171 CTANSWNVIPSCQQK-CDIPSLSNG-------LISGSTFSIGGVIHLSCKSGFtltgSPSS-------TCIDGKWNPVLP 235

                  ....
gi 109627652  403 -CVR 405
Cdd:PHA02954  236 iCVR 239
Sushi pfam00084
Sushi repeat (SCR repeat);
103-159 1.21e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.95  E-value: 1.21e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652   103 CGHPGDTPFGSFRlAVGSQFEFGAKVVYTCDDGYQLLGEiDYRECGADG-WINDIPLC 159
Cdd:pfam00084    1 CPPPPDIPNGKVS-ATKNEYNYGASVSYECDPGYRLVGS-PTITCQEDGtWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
885-949 1.27e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.95  E-value: 1.27e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652   885 CSQPPTIEHGSInlprsseerrdSIESSSHEHGTTFSYVCDDGFRIPEENRITC-YMGKWS-TPPRC 949
Cdd:pfam00084    1 CPPPPDIPNGKV-----------SATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
708-761 1.49e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.95  E-value: 1.49e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652   708 CGDIPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVSCI-SGKWTQL-PKC 761
Cdd:pfam00084    1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
43-280 1.55e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.46  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652   43 PPRENSEILSgswSEQLYPEGTQATYKCRPGYRTLGTIVkVCKNGKWVASNPSricrKKPCGHPGDTPfgsfRLAVGSQF 122
Cdd:PHA02954   24 PTMNNAKLTS---TETSFNDKQKVTFTCDSGYYSLDPNA-VCETDKWKYENPC----KKMCTVSDYVS----ELYDKPLY 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  123 EFGAKVVYTCDDgyqllgEIDYREC----GADGWiNDIPLCEVVKCLPVtELENGrivsGAAETDQEYYFGQVVRFECNS 198
Cdd:PHA02954   92 EVNSTITLICKD------ETKYFRCeeknGNTSW-NDTVTCPNAECQPL-QLEHG----SCQPVKEKYSFGEHITINCDV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  199 GFKIEGHKEIHCSENGlWsNEKPRCVEiLCTPPRVENgdGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGSGWSS-Q 277
Cdd:PHA02954  160 GYEVIGASYISCTANS-W-NVIPSCQQ-KCDIPSLSN--GLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPvL 234

                  ...
gi 109627652  278 PFC 280
Cdd:PHA02954  235 PIC 237
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
335-558 1.74e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.08  E-value: 1.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  335 VPRCTLKPCEFPQFKYGRLYYEESlrpnfPVSIGNKYSYKCDNGFsppsgYSWD-YLRCTAQGWEPEVPCVRKC-VFHYV 412
Cdd:PHA02954   13 LPAVVYSTCTVPTMNNAKLTSTET-----SFNDKQKVTFTCDSGY-----YSLDpNAVCETDKWKYENPCKKMCtVSDYV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  413 EngdSAYWEKVYVQGQSLKVQC-----YNGYSLQNGQ----DTMTCtengwsPPPKCiriktcsaSDIHIDNGFLSESSS 483
Cdd:PHA02954   83 S---ELYDKPLYEVNSTITLICkdetkYFRCEEKNGNtswnDTVTC------PNAEC--------QPLQLEHGSCQPVKE 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  484 IYALNRETSYRCKQGYvtntgEISGS--ITCLQNGWSPQPSCIKSCDMPVFENSITKNTRtwFKLNDKLDYECLVGF 558
Cdd:PHA02954  146 KYSFGEHITINCDVGY-----EVIGAsyISCTANSWNVIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGF 215
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
229-281 2.24e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 2.24e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 109627652  229 TPPRVENGDGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGSG-WS-SQPFCE 281
Cdd:cd00033     3 PPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGgWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
826-879 2.49e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.20  E-value: 2.49e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 109627652    826 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMVC-KDGRW-QSLPRC 879
Cdd:smart00032    1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWsPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
39-99 2.83e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 2.83e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 109627652   39 CKGPPPRENSEILSgswSEQLYPEGTQATYKCRPGYRTLGTIVKVC-KNGKWvaSNPSRICR 99
Cdd:cd00033     1 CPPPPVPENGTVTG---SKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGW--SPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
287-338 4.82e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.43  E-value: 4.82e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 109627652    287 PPYILNGIYTPHRIIHRSDDEIRYECNYGFYPVtGSTVSKCTPTG-W-IPVPRC 338
Cdd:smart00032    4 PPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWsPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
39-95 5.31e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.05  E-value: 5.31e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 109627652     39 CKGPPPRENSEILSgswSEQLYPEGTQATYKCRPGYRTLGTIVKVC-KNGKWVASNPS 95
Cdd:smart00032    1 CPPPPDIENGTVTS---SSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPPPT 55
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
229-280 5.81e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.05  E-value: 5.81e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 109627652    229 TPPRVENGDGINVKPVYKENERYHYKCKHGYVPKERGDAVCTGSG-WS-SQPFC 280
Cdd:smart00032    3 PPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
285-338 7.36e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.98  E-value: 7.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  285 CSPPY-ILNGIYTPHRIIHRSDDEIRYECNYGFYPVtGSTVSKCTPTG-WIP-VPRC 338
Cdd:cd00033     1 CPPPPvPENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
711-981 2.76e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 41.23  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  711 IPELEHGSAKCSVPPYHHGDSVEFICEENFTMIGHGSVsCISGKWTQLPKCVatdqlEKCRVLKSTGIEAIKPKlteFTH 790
Cdd:PHA02954   23 VPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKYENPCK-----KMCTVSDYVSELYDKPL---YEV 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  791 NSTMDYKCRDKQEYERSICINGKWDPEPNCTSKTSCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDSEEMVCKD 870
Cdd:PHA02954   94 NSTITLICKDETKYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTA 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  871 GRWQSLPRCIEKipcSQPPTIEHGSINlprsseerrdsieSSSHEHGTTFSYVCDDGFRIPEENRITCYMGKWS-TPPRC 949
Cdd:PHA02954  174 NSWNVIPSCQQK---CDIPSLSNGLIS-------------GSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNpVLPIC 237
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 109627652  950 V-------GLPCGPPPSIPLGTVSLELESYQH---GEEVTYH 981
Cdd:PHA02954  238 VrsneefdPVDDGPDDETDLSKLSKDVVQYEQeieSLEATYH 279
Sushi pfam00084
Sushi repeat (SCR repeat);
41-94 2.86e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.09  E-value: 2.86e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 109627652    41 GPPPRENSEILSGSWSEqlYPEGTQATYKCRPGYRTLGTIVKVC-KNGKWVASNP 94
Cdd:pfam00084    2 PPPPDIPNGKVSATKNE--YNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPFP 54
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
1005-1193 3.58e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 41.23  E-value: 3.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1005 PKCIKTDCDVlPTVKNAIIRgKSKKSYRTGEQVTFRCQSPYQMNGSDTVtCVNSRWIGQPVCKDNSCVdpphvpnATIVT 1084
Cdd:PHA02954   14 PAVVYSTCTV-PTMNNAKLT-STETSFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKYENPCKKMCTV-------SDYVS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652 1085 RTKNKYLhgdrvrYECNKPLELFGQVEVM---CE----NGIWTEKPKCRDSTGKcgpPPPIDNGDITslslPVYEPLSSV 1157
Cdd:PHA02954   84 ELYDKPL------YEVNSTITLICKDETKyfrCEekngNTSWNDTVTCPNAECQ---PLQLEHGSCQ----PVKEKYSFG 150
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 109627652 1158 EY---QCQKYYLLKGKKTITCRNGKWSEPPTCLHACVIP 1193
Cdd:PHA02954  151 EHitiNCDVGYEVIGASYISCTANSWNVIPSCQQKCDIP 189
PHA02817 PHA02817
EEV Host range protein; Provisional
640-765 3.61e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 40.31  E-value: 3.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109627652  640 CKGQVASCAPPLEILNGEINGaKKVEYSHGEVVKYDCKP-----RFLLKGPNKIQC-VDGNWTT-LPVCieeERTCGDIP 712
Cdd:PHA02817   17 SLCDLNKCCYPPSIKNGYIYN-KKTEYNIGSNVTFFCGNntrgvRYTLVGEKNIICeKDGKWNKeFPVC---KIIRCRFP 92
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 109627652  713 ELEHG--SAKCSVPPYHHGDSVEFICEENFTMIGHG-SVSCISGKW-TQLPKCVATD 765
Cdd:PHA02817   93 ALQNGfvNGIPDSKKFYYESEVSFSCKPGFVLIGTKySVCGINSSWiPKVPICSRDN 149
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
472-524 3.96e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 36.67  E-value: 3.96e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 109627652  472 HIDNGFLSESSSIYALNRETSYRCKQGYVTNTgeiSGSITCLQNG-WSP-QPSCI 524
Cdd:cd00033     6 VPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSPpPPTCE 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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