NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|255760039|ref|NP_034832|]
View 

leukocyte cell-derived chemotaxin-2 precursor [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Peptidase_M23 super family cl38048
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ...
 51-147 4.76e-05

Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.


The actual alignment was detected with superfamily member pfam01551:

Pssm-ID: 460250 [Multi-domain]  Cd Length: 96  Bit Score: 39.84  E-value: 4.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255760039   51 RHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAIndgIRLSGRGFCVKIFYIKPI--KYKGSIKKGEKLGTLLPLQK 128
Cdd:pfam01551   1 RFHKGIDIAAPTGTPVYAAADGVVVFAGWLGGYGNLV---IIDHGNGYSTLYAHLSSIlvKVGQRVKAGQVIGTVGSTGR 77

                          90       100
                  ....*....|....*....|..
gi 255760039  129 VYpgiQSHVHVE---NCDSSDP 147
Cdd:pfam01551  78 ST---GPHLHFEirkNGKPVDP 96
 
Name Accession Description Interval E-value
Peptidase_M23 pfam01551
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ...
 51-147 4.76e-05

Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.


Pssm-ID: 460250 [Multi-domain]  Cd Length: 96  Bit Score: 39.84  E-value: 4.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255760039   51 RHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAIndgIRLSGRGFCVKIFYIKPI--KYKGSIKKGEKLGTLLPLQK 128
Cdd:pfam01551   1 RFHKGIDIAAPTGTPVYAAADGVVVFAGWLGGYGNLV---IIDHGNGYSTLYAHLSSIlvKVGQRVKAGQVIGTVGSTGR 77

                          90       100
                  ....*....|....*....|..
gi 255760039  129 VYpgiQSHVHVE---NCDSSDP 147
Cdd:pfam01551  78 ST---GPHLHFEirkNGKPVDP 96
 
Name Accession Description Interval E-value
Peptidase_M23 pfam01551
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ...
 51-147 4.76e-05

Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.


Pssm-ID: 460250 [Multi-domain]  Cd Length: 96  Bit Score: 39.84  E-value: 4.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255760039   51 RHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAIndgIRLSGRGFCVKIFYIKPI--KYKGSIKKGEKLGTLLPLQK 128
Cdd:pfam01551   1 RFHKGIDIAAPTGTPVYAAADGVVVFAGWLGGYGNLV---IIDHGNGYSTLYAHLSSIlvKVGQRVKAGQVIGTVGSTGR 77

                          90       100
                  ....*....|....*....|..
gi 255760039  129 VYpgiQSHVHVE---NCDSSDP 147
Cdd:pfam01551  78 ST---GPHLHFEirkNGKPVDP 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH