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Conserved domains on  [gi|257467636|ref|NP_055646|]
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TPR and ankyrin repeat-containing protein 1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HelD super family cl28314
DNA helicase IV [Replication, recombination and repair];
1393-1589 3.26e-11

DNA helicase IV [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG3973:

Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1393 DEIQDFTQAELALLMKCIndPNSMF-LTGDTAQSImkgvaFRFSDLRSLfhyasRNTIDKqcAVRKPKKIHQLYQNYRSH 1471
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGAESW-----EEVLEP--LGGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1472 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTVLESCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1541
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 257467636 1542 -----LVANETAKEKIPEELGLA---LVLTIYEAKGLEFDDVLLYNFftDSEAYKE 1589
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
450-600 8.31e-10

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 62.66  E-value: 8.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  450 LIDSGALPDGLQESQERPVVTCLKHEDFELAFLLLTKGADPRAISlTEGDTPLHAA--------LHIFLEIKADIgfsfl 521
Cdd:COG0666   106 LLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQD-NDGNTPLHLAaangnleiVKLLLEAGADV----- 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257467636  522 shlldlfwsnptefdylnpNVQDSNGNTLMHILFQKGMLKRVKklldLLVKFDINFNLKNKEGKDARHRIKKNDSLLLA 600
Cdd:COG0666   180 -------------------NARDNDGETPLHLAAENGHLEIVK----LLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR super family cl34000
Ankyrin repeat [Signal transduction mechanisms];
183-353 9.77e-09

Ankyrin repeat [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG0666:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 59.58  E-value: 9.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  183 PKLVQWLISIGASVETIGPYPLHALMRLciqARENHL--FRWLMDHKPEwkgrINQKDGDGCTVLHVVAAHspgylvkRQ 260
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLHLA---AANGNLeiVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GH 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  261 TEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKINSHLEKLATcsKDLSGFSNGDGPTSENDIFRKVLEQLVKY 340
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNA--KDKDGLTALLLAAAAGAALIVKLLLLALL 276

                         170
                  ....*....|...
gi 257467636  341 MNSGNRLLHKNFL 353
Cdd:COG0666   277 LLAAALLDLLTLL 289
TPR super family cl33886
Tetratricopeptide (TPR) repeat [General function prediction only];
12-78 3.94e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


The actual alignment was detected with superfamily member COG0457:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 3.94e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 257467636   12 RDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFFEGLRL 78
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL 105
 
Name Accession Description Interval E-value
HelD COG3973
DNA helicase IV [Replication, recombination and repair];
1393-1589 3.26e-11

DNA helicase IV [Replication, recombination and repair];


Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1393 DEIQDFTQAELALLMKCIndPNSMF-LTGDTAQSImkgvaFRFSDLRSLfhyasRNTIDKqcAVRKPKKIHQLYQNYRSH 1471
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGAESW-----EEVLEP--LGGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1472 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTVLESCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1541
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 257467636 1542 -----LVANETAKEKIPEELGLA---LVLTIYEAKGLEFDDVLLYNFftDSEAYKE 1589
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
450-600 8.31e-10

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 62.66  E-value: 8.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  450 LIDSGALPDGLQESQERPVVTCLKHEDFELAFLLLTKGADPRAISlTEGDTPLHAA--------LHIFLEIKADIgfsfl 521
Cdd:COG0666   106 LLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQD-NDGNTPLHLAaangnleiVKLLLEAGADV----- 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257467636  522 shlldlfwsnptefdylnpNVQDSNGNTLMHILFQKGMLKRVKklldLLVKFDINFNLKNKEGKDARHRIKKNDSLLLA 600
Cdd:COG0666   180 -------------------NARDNDGETPLHLAAENGHLEIVK----LLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
183-353 9.77e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 59.58  E-value: 9.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  183 PKLVQWLISIGASVETIGPYPLHALMRLciqARENHL--FRWLMDHKPEwkgrINQKDGDGCTVLHVVAAHspgylvkRQ 260
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLHLA---AANGNLeiVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GH 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  261 TEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKINSHLEKLATcsKDLSGFSNGDGPTSENDIFRKVLEQLVKY 340
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNA--KDKDGLTALLLAAAAGAALIVKLLLLALL 276

                         170
                  ....*....|...
gi 257467636  341 MNSGNRLLHKNFL 353
Cdd:COG0666   277 LLAAALLDLLTLL 289
PHA03095 PHA03095
ankyrin-like protein; Provisional
 180-351 1.83e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 46.94  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  180 EQVPKLVQWLISIGASVETI---GPYPLHALMRLCIQARenhLFRWLMDHKpewkGRINQKDGDGCTVLHVvaahspgYL 256
Cdd:PHA03095   60 EKVKDIVRLLLEAGADVNAPercGFTPLHLYLYNATTLD---VIKLLIKAG----ADVNAKDKVGRTPLHV-------YL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  257 -VKRQTEDV-QMLLRFGADPTLLDRQSRSVVDVLKRNKNfkaiekINSHLEKLAtcskdlsgFSNGDGPTSENDIFRKVL 334
Cdd:PHA03095  126 sGFNINPKViRLLLRKGADVNALDLYGMTPLAVLLKSRN------ANVELLRLL--------IDAGADVYAVDDRFRSLL 191

                         170
                  ....*....|....*..
gi 257467636  335 EQLVKYMNSGNRLLHKN 351
Cdd:PHA03095  192 HHHLQSFKPRARIVREL 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
12-78 3.94e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 3.94e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 257467636   12 RDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFFEGLRL 78
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL 105
Ank_2 pfam12796
Ankyrin repeats (3 copies);
183-278 2.41e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 39.33  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636   183 PKLVQWLISIGASVETIGPYPLHALMrLCIQARENHLFRWLMDHkpewkGRINQKDgDGCTVLHVVAAHspgylvkRQTE 262
Cdd:pfam12796   10 LELVKLLLENGADANLQDKNGRTALH-LAAKNGHLEIVKLLLEH-----ADVNLKD-NGRTALHYAARS-------GHLE 75

                           90
                   ....*....|....*.
gi 257467636   263 DVQMLLRFGADPTLLD 278
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
 
Name Accession Description Interval E-value
HelD COG3973
DNA helicase IV [Replication, recombination and repair];
1393-1589 3.26e-11

DNA helicase IV [Replication, recombination and repair];


Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1393 DEIQDFTQAELALLMKCIndPNSMF-LTGDTAQSImkgvaFRFSDLRSLfhyasRNTIDKqcAVRKPKKIHQLYQNYRSH 1471
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGAESW-----EEVLEP--LGGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1472 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTVLESCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1541
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 257467636 1542 -----LVANETAKEKIPEELGLA---LVLTIYEAKGLEFDDVLLYNFftDSEAYKE 1589
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
450-600 8.31e-10

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 62.66  E-value: 8.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  450 LIDSGALPDGLQESQERPVVTCLKHEDFELAFLLLTKGADPRAISlTEGDTPLHAA--------LHIFLEIKADIgfsfl 521
Cdd:COG0666   106 LLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQD-NDGNTPLHLAaangnleiVKLLLEAGADV----- 179

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257467636  522 shlldlfwsnptefdylnpNVQDSNGNTLMHILFQKGMLKRVKklldLLVKFDINFNLKNKEGKDARHRIKKNDSLLLA 600
Cdd:COG0666   180 -------------------NARDNDGETPLHLAAENGHLEIVK----LLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
183-353 9.77e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 59.58  E-value: 9.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  183 PKLVQWLISIGASVETIGPYPLHALMRLciqARENHL--FRWLMDHKPEwkgrINQKDGDGCTVLHVVAAHspgylvkRQ 260
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLHLA---AANGNLeiVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GH 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  261 TEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKINSHLEKLATcsKDLSGFSNGDGPTSENDIFRKVLEQLVKY 340
Cdd:COG0666   199 LEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNA--KDKDGLTALLLAAAAGAALIVKLLLLALL 276

                         170
                  ....*....|...
gi 257467636  341 MNSGNRLLHKNFL 353
Cdd:COG0666   277 LLAAALLDLLTLL 289
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
418-620 1.48e-06

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 52.65  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  418 LIKDCNFSDLDICTIIPHLSTWDQRKKQLLGCLIDSGALPDGLQESQERPVVTCLKHEDFELAFLLLTKGADPRAISlTE 497
Cdd:COG0666    41 LLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARD-KD 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  498 GDTPLH-AALHIFLEIkadigfsfLSHLLDLfwsnptefdYLNPNVQDSNGNTLMHILFQKGMLKRVKklldLLVKFDIN 576
Cdd:COG0666   120 GETPLHlAAYNGNLEI--------VKLLLEA---------GADVNAQDNDGNTPLHLAAANGNLEIVK----LLLEAGAD 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 257467636  577 FNLKNKEGKDARHRIKKNDSLLLAwnKALME-----NRRRSRQDSAAHL 620
Cdd:COG0666   179 VNARDNDGETPLHLAAENGHLEIV--KLLLEagadvNAKDNDGKTALDL 225
PHA03095 PHA03095
ankyrin-like protein; Provisional
 180-351 1.83e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 46.94  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  180 EQVPKLVQWLISIGASVETI---GPYPLHALMRLCIQARenhLFRWLMDHKpewkGRINQKDGDGCTVLHVvaahspgYL 256
Cdd:PHA03095   60 EKVKDIVRLLLEAGADVNAPercGFTPLHLYLYNATTLD---VIKLLIKAG----ADVNAKDKVGRTPLHV-------YL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  257 -VKRQTEDV-QMLLRFGADPTLLDRQSRSVVDVLKRNKNfkaiekINSHLEKLAtcskdlsgFSNGDGPTSENDIFRKVL 334
Cdd:PHA03095  126 sGFNINPKViRLLLRKGADVNALDLYGMTPLAVLLKSRN------ANVELLRLL--------IDAGADVYAVDDRFRSLL 191

                         170
                  ....*....|....*..
gi 257467636  335 EQLVKYMNSGNRLLHKN 351
Cdd:PHA03095  192 HHHLQSFKPRARIVREL 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
12-78 3.94e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 3.94e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 257467636   12 RDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFFEGLRL 78
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL 105
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 5-93 1.19e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.60  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636    5 RAARVPPrDLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFfegLRLVQRSQD 84
Cdd:COG3914   137 RALALNP-DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY---RRALELDPD 212


                  ....*....
gi 257467636   85 QAPVADFLV 93
Cdd:COG3914   213 NADAHSNLL 221
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 235-320 2.02e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 43.73  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636  235 NQKDGDGCTVLHVVAAHspGYLvkrqtEDVQMLLRFGADPTLLDRQSRSVVDVLKRNKNFKAIEKINSHleklatCSKDL 314
Cdd:PTZ00322  109 NCRDYDGRTPLHIACAN--GHV-----QVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRH------SQCHF 175


                  ....*.
gi 257467636  315 SGFSNG 320
Cdd:PTZ00322  176 ELGANA 181
Ank_2 pfam12796
Ankyrin repeats (3 copies);
183-278 2.41e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 39.33  E-value: 2.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636   183 PKLVQWLISIGASVETIGPYPLHALMrLCIQARENHLFRWLMDHkpewkGRINQKDgDGCTVLHVVAAHspgylvkRQTE 262
Cdd:pfam12796   10 LELVKLLLENGADANLQDKNGRTALH-LAAKNGHLEIVKLLLEH-----ADVNLKD-NGRTALHYAARS-------GHLE 75

                           90
                   ....*....|....*.
gi 257467636   263 DVQMLLRFGADPTLLD 278
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
UvrD COG0210
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
1342-1483 2.45e-03

Superfamily I DNA or RNA helicase [Replication, recombination and repair];


Pssm-ID: 439980 [Multi-domain]  Cd Length: 721  Bit Score: 43.39  E-value: 2.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1342 EDRSEIYSLFSLYQQIRSQKGYFDEEDVLYNiSRRLskLRVLPWsIHELYG--------DEIQDFTQAELALLMKCINDP 1413
Cdd:COG0210   164 PEWRAAAELYEAYQERLRANNALDFDDLLLL-AVRL--LEENPE-VLEKYQnrfryilvDEYQDTNPAQYELLRLLAGDG 239

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257467636 1414 NSMFLTGDTAQSIMkgvAFRFSDLRSLFHYASRntidkqcavRKPKKIHQLYQNYRSHSGILNLASGVVD 1483
Cdd:COG0210   240 RNLCVVGDDDQSIY---GFRGADPENILRFEKD---------FPDAKVIKLEQNYRSTQNILDAANAVIA 297
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
13-78 5.02e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 5.02e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257467636   13 DLAVLLCNKSNAFFSLGKWNEAFVAAKECLQWDPTYVKGYYRAGYSLLRLHQPYEAARMFFEGLRL 78
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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