|
Name |
Accession |
Description |
Interval |
E-value |
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
694-844 |
3.51e-28 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 111.30 E-value: 3.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 694 YDAYFCFS-SKDFEWAQNALLKHLDahyssRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEA 772
Cdd:pfam01582 1 YDVFLSFRgSDTREWFVSHLLKELK-----QKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 773 FRYAQSRSLsDLKSILIVVVVGSLSQYQL-------MRHETIRGFLQKQQYLRWPEDL------------QDVGWFLDKL 833
Cdd:pfam01582 76 LVKILECAL-DLGQKVIPIFYEVDPSDVRkqtgsfgKAFKKHKKVLTEEKVLKWRGALnevaniwhsksvSDESKFWKKI 154
|
170
....*....|.
gi 1883538051 834 SGCILKEEKGK 844
Cdd:pfam01582 155 AYDISNKLNGT 165
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
693-828 |
3.09e-26 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 104.71 E-value: 3.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 693 RYDAYFCFSSKDfeWAQNALLKHLdahYSSRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEA 772
Cdd:smart00255 1 EYDVFISYSGKE--DVRNEFLSHL---LEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 773 FRYAQSRSLSDLKSILIVVVVGSLSQYQLMRHETIRGFLQKqQYLRWPEDLQDVGW 828
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKK-NYLKWPEDEKEQFW 130
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
308-582 |
1.16e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.44 E-value: 1.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 308 LFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTL 387
Cdd:COG4886 19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 388 QTLDLRDNalKAIGFIPSIQMVLLGGNKLVHLPHI--HFTA-NFLELSENRLENLSDlyFLLRVPQLQFLILNQNRLSSC 464
Cdd:COG4886 99 TELDLSGN--EELSNLTNLESLDLSGNQLTDLPEElaNLTNlKELDLSNNQLTDLPE--PLGNLTNLKSLDLSNNQLTDL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 465 KAAhtPSENPSLEQLFLTENMLQ-LAwetglcwDVFQGLSRLQILYLSNNYLNFLPPGIFNdLVALRMLSLSANKLTVLS 543
Cdd:COG4886 175 PEE--LGNLTNLKELDLSNNQITdLP-------EPLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNNQLTDLP 244
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1883538051 544 P-GSLPaNLEILDISRNQLFS-PDPALFSSLRVLDITHNEF 582
Cdd:COG4886 245 ElGNLT-NLEELDLSNNQLTDlPPLANLTNLKTLDLSNNQL 284
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
383-583 |
3.69e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 67.03 E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 383 LLKTLQTLDLRDNALKAI-GFIP-SIQMVLLGGNKLVHLP-HIHFTANFLELSENRLENLSDlyfllRVPQ-LQFLILNQ 458
Cdd:PRK15370 218 LQGNIKTLYANSNQLTSIpATLPdTIQEMELSINRITELPeRLPSALQSLDLFHNKISCLPE-----NLPEeLRYLSVYD 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 459 NRLSSCkAAHTPSenpSLEQLFLTENMLQLAWETglcwdvfqgLS-RLQILYLSNNYLNFLPPGIfndLVALRMLSLSAN 537
Cdd:PRK15370 293 NSIRTL-PAHLPS---GITHLNVQSNSLTALPET---------LPpGLKTLEAGENALTSLPASL---PPELQVLDVSKN 356
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1883538051 538 KLTVLsPGSLPANLEILDISRNQLFSPDPALFSSLRVLDITHNEFV 583
Cdd:PRK15370 357 QITVL-PETLPPTITTLDVSRNALTNLPENLPAALQIMQASRNNLV 401
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
294-349 |
8.24e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.92 E-value: 8.24e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 294 LDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLL 349
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
85-132 |
1.74e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 1.74e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1883538051 85 LTIGPGAFRNLPNLRILDLGQSQIEVLNRDAFQGLPHLLELRLFSCGL 132
Cdd:pfam13855 14 TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
84-319 |
2.67e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 53.78 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 84 NLTIGPGAFRNLPNLRILDLGQSQIEVLNrDAFQGLPHLLELRLFSCGLSSAvlsdGYFRNLYSLARLDLSGNQIHSLrl 163
Cdd:COG4886 193 QITDLPEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDL----PELGNLTNLEELDLSNNQLTDL-- 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 164 hSSFRELNSLSDVNFAFNQIFTICEDELEPLQGKTlsffglKLTKLFSRVSVGWETCRNPFRGVRLETLDLSENGWTVDI 243
Cdd:COG4886 266 -PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN------SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLT 338
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 244 TRNFSNIIQGSQISSLILKHHIMGPGFGFQNIRDPDQSTFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLN 319
Cdd:COG4886 339 TLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
339-581 |
7.81e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 51.97 E-value: 7.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 339 LQVLNLSYNLLGELynsnfyGLPRVAYVdlqrnhigiIQDQtfrllKTLQTLDLRDNALKAIG-FIPSIQMVLLGGNKLV 417
Cdd:cd00116 25 LQVLRLEGNTLGEE------AAKALASA---------LRPQ-----PSLKELCLSLNETGRIPrGLQSLLQGLTKGCGLQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 418 HLPhiHFTANFLELSENRLENlsdlyfLLRVPQLQFLILNQNRLSSCKAAHT----PSENPSLEQLFLTENMLqlawETG 493
Cdd:cd00116 85 ELD--LSDNALGPDGCGVLES------LLRSSSLQELKLNNNGLGDRGLRLLakglKDLPPALEKLVLGRNRL----EGA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 494 LCWD---VFQGLSRLQILYLSNNylNFLPPGI------FNDLVALRMLSLSANKLTVLSPGSL------PANLEILDISR 558
Cdd:cd00116 153 SCEAlakALRANRDLKELNLANN--GIGDAGIralaegLKANCNLEVLDLNNNGLTDEGASALaetlasLKSLEVLNLGD 230
|
250 260 270
....*....|....*....|....*....|.
gi 1883538051 559 NQLFSPD--------PALFSSLRVLDITHNE 581
Cdd:cd00116 231 NNLTDAGaaalasalLSPNISLLTLSLSCND 261
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
555-633 |
3.30e-05 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 47.77 E-value: 3.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 555 DISRNQLFSPDPALFS---SLRVLDITHNEFVCNCELSTFISWLNQTNVTLFgSPADVYCMYPNSLLGGSLYNIS--TED 629
Cdd:TIGR00864 1 DISNNKISTIEEGICAnlcNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVR-QPEAALCAGPGALAGQPLLGIPllDSG 79
|
....
gi 1883538051 630 CDEE 633
Cdd:TIGR00864 80 CDEE 83
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
92-181 |
1.50e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.92 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 92 FRNLPNLRILDLGQSQIEVLNrdAFQGLPHLLELRL------------FSCGLSSAVL--------------SDGYFRNL 145
Cdd:cd21340 64 LENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIenqrlppgekltFDPRSLAALSnslrvlnisgnnidSLEPLAPL 141
|
90 100 110
....*....|....*....|....*....|....*..
gi 1883538051 146 YSLARLDLSGNQIHSLR-LHSSFRELNSLSDVNFAFN 181
Cdd:cd21340 142 RNLEQLDASNNQISDLEeLLDLLSSWPSLRELDLTGN 178
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
580-631 |
9.38e-03 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 35.10 E-value: 9.38e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1883538051 580 NEFVCNCELSTFISWLNQTNVtlFGSPADVYCMYPNSLLGGSL-YNISTEDCD 631
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEH--LQDPVDLRCASPSSLRGPLLeLLHSEFKCP 51
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
694-844 |
3.51e-28 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 111.30 E-value: 3.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 694 YDAYFCFS-SKDFEWAQNALLKHLDahyssRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEA 772
Cdd:pfam01582 1 YDVFLSFRgSDTREWFVSHLLKELK-----QKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 773 FRYAQSRSLsDLKSILIVVVVGSLSQYQL-------MRHETIRGFLQKQQYLRWPEDL------------QDVGWFLDKL 833
Cdd:pfam01582 76 LVKILECAL-DLGQKVIPIFYEVDPSDVRkqtgsfgKAFKKHKKVLTEEKVLKWRGALnevaniwhsksvSDESKFWKKI 154
|
170
....*....|.
gi 1883538051 834 SGCILKEEKGK 844
Cdd:pfam01582 155 AYDISNKLNGT 165
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
693-828 |
3.09e-26 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 104.71 E-value: 3.09e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 693 RYDAYFCFSSKDfeWAQNALLKHLdahYSSRNRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEA 772
Cdd:smart00255 1 EYDVFISYSGKE--DVRNEFLSHL---LEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDE 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 773 FRYAQSRSLSDLKSILIVVVVGSLSQYQLMRHETIRGFLQKqQYLRWPEDLQDVGW 828
Cdd:smart00255 76 LVAALENALEEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKK-NYLKWPEDEKEQFW 130
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
308-582 |
1.16e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.44 E-value: 1.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 308 LFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTL 387
Cdd:COG4886 19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 388 QTLDLRDNalKAIGFIPSIQMVLLGGNKLVHLPHI--HFTA-NFLELSENRLENLSDlyFLLRVPQLQFLILNQNRLSSC 464
Cdd:COG4886 99 TELDLSGN--EELSNLTNLESLDLSGNQLTDLPEElaNLTNlKELDLSNNQLTDLPE--PLGNLTNLKSLDLSNNQLTDL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 465 KAAhtPSENPSLEQLFLTENMLQ-LAwetglcwDVFQGLSRLQILYLSNNYLNFLPPGIFNdLVALRMLSLSANKLTVLS 543
Cdd:COG4886 175 PEE--LGNLTNLKELDLSNNQITdLP-------EPLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNNQLTDLP 244
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1883538051 544 P-GSLPaNLEILDISRNQLFS-PDPALFSSLRVLDITHNEF 582
Cdd:COG4886 245 ElGNLT-NLEELDLSNNQLTDlPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
305-660 |
9.65e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 77.28 E-value: 9.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 305 NPRLFGTLKDLKMLNLAFNKINKIGEnAFYGLDSLQVLNLSYNLLGELyNSNFYGLPRVAYVDLQRNHIGIIqDQTFRLL 384
Cdd:COG4886 105 GNEELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNL 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 385 KTLQTLDLRDNALKAIGfipsiqmvllggNKLVHLPHIhftaNFLELSENRLENLSDlyFLLRVPQLQFLILNQNRLSSC 464
Cdd:COG4886 182 TNLKELDLSNNQITDLP------------EPLGNLTNL----EELDLSGNQLTDLPE--PLANLTNLETLDLSNNQLTDL 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 465 kaahtpsenPSLEQLfltenmlqlawetglcwdvfqglSRLQILYLSNNYLNFLPPGIfnDLVALRMLSLSANKLTVLSP 544
Cdd:COG4886 244 ---------PELGNL-----------------------TNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKL 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 545 GSLPANLEILDISRNQLFSPDPALFSSLRVLDITHNEFVCNCELSTFISWLNQTNVTLFGSPADVYCMYPNSLLGGSLYN 624
Cdd:COG4886 290 KELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTL 369
|
330 340 350
....*....|....*....|....*....|....*.
gi 1883538051 625 ISTEDCDEEEAMRSLKFSLFILCTVTLTLFLVITLV 660
Cdd:COG4886 370 GLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTL 405
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
246-561 |
1.83e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.51 E-value: 1.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 246 NFSNIIQGSQISSLILKHHIMGPGFGFQNIRDPDQSTFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKI 325
Cdd:COG4886 5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 326 NKIGENAFYGLDSLQVLNLSYNllgelynSNFYGLPRVAYVDLQRNHIGIIqDQTFRLLKTLQTLDLRDNALKAIGfips 405
Cdd:COG4886 85 LLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLP---- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 406 iqmvllggNKLVHLPHIHFtanfLELSENRLENLSDlyFLLRVPQLQFLILNQNRLSSckAAHTPSENPSLEQLFLTENM 485
Cdd:COG4886 153 --------EPLGNLTNLKS----LDLSNNQLTDLPE--ELGNLTNLKELDLSNNQITD--LPEPLGNLTNLEELDLSGNQ 216
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1883538051 486 LQ-LAWEtglcwdvFQGLSRLQILYLSNNYLNFLPpgIFNDLVALRMLSLSANKLTVLSPGSLPANLEILDISRNQL 561
Cdd:COG4886 217 LTdLPEP-------LANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
383-583 |
3.69e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 67.03 E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 383 LLKTLQTLDLRDNALKAI-GFIP-SIQMVLLGGNKLVHLP-HIHFTANFLELSENRLENLSDlyfllRVPQ-LQFLILNQ 458
Cdd:PRK15370 218 LQGNIKTLYANSNQLTSIpATLPdTIQEMELSINRITELPeRLPSALQSLDLFHNKISCLPE-----NLPEeLRYLSVYD 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 459 NRLSSCkAAHTPSenpSLEQLFLTENMLQLAWETglcwdvfqgLS-RLQILYLSNNYLNFLPPGIfndLVALRMLSLSAN 537
Cdd:PRK15370 293 NSIRTL-PAHLPS---GITHLNVQSNSLTALPET---------LPpGLKTLEAGENALTSLPASL---PPELQVLDVSKN 356
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1883538051 538 KLTVLsPGSLPANLEILDISRNQLFSPDPALFSSLRVLDITHNEFV 583
Cdd:PRK15370 357 QITVL-PETLPPTITTLDVSRNALTNLPENLPAALQIMQASRNNLV 401
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
294-349 |
8.24e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.92 E-value: 8.24e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 294 LDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLL 349
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
503-561 |
1.75e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 57.15 E-value: 1.75e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1883538051 503 SRLQILYLSNNYLNFLPPGIFNDLVALRMLSLSANKLTVLSPGSL--PANLEILDISRNQL 561
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFsgLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
315-373 |
8.12e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.22 E-value: 8.12e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1883538051 315 LKMLNLAFNKINKIGENAFYGLDSLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHI 373
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
37-479 |
8.19e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.87 E-value: 8.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 37 NLTQIPWILNTTTERLLLSFNYISMVVATSFPLLERLQLLELGTQYANLTIGPGAFRNLPNLRILDLGqsqievlNRDAF 116
Cdd:COG4886 37 LLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLS-------GNEEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 117 QGLPHLLELRLFSCGLSSAvlsDGYFRNLYSLARLDLSGNQIHSLrlHSSFRELNSLSDVNFAFNQIFTIcEDELEPLQG 196
Cdd:COG4886 110 SNLTNLESLDLSGNQLTDL---PEELANLTNLKELDLSNNQLTDL--PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 197 -KTLSFFGLKLTKLFSRVSvgweTCRNpfrgvrLETLDLSENgwtvditrnfsniiqgsQISSLilkhhimgpgfgfqni 275
Cdd:COG4886 184 lKELDLSNNQITDLPEPLG----NLTN------LEELDLSGN-----------------QLTDL---------------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 276 rdpdqstFASLARSSVLQ-LDLSHGFIFSLnPRLfGTLKDLKMLNLAFNKINKIGENAfyGLDSLQVLNLSYNLLGELYN 354
Cdd:COG4886 221 -------PEPLANLTNLEtLDLSNNQLTDL-PEL-GNLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKL 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 355 SNFYGLPRVAyvDLQRNHIGIIQDQTFRLLKTLQTLDLRDNALKAIGFIPSIQMVLLGGNKLVHLPHIHFTANFLELSEN 434
Cdd:COG4886 290 KELELLLGLN--SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLL 367
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1883538051 435 RLENLSDLYFLLRVPQLQFLILNQNRLSSCKAAHTPSENPSLEQL 479
Cdd:COG4886 368 TLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVN 412
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
474-539 |
2.06e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.07 E-value: 2.06e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 474 PSLEQLFLTENMLqlaweTGLCWDVFQGLSRLQILYLSNNYLNFLPPGIFNDLVALRMLSLSANKL 539
Cdd:pfam13855 1 PNLRSLDLSNNRL-----TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
697-793 |
3.21e-09 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 55.40 E-value: 3.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 697 YFCFSSKDFEWAQnALLKHLDAHyssrnRLRLCFEERDFIPGENHISNIQAAVWGSRKTVCLVSRHFLKDGWCLEAFRYA 776
Cdd:pfam13676 2 FISYAGEDRAWAE-WLADALEAA-----GYRVWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAA 75
|
90
....*....|....*..
gi 1883538051 777 QSRSLSDLKsiLIVVVV 793
Cdd:pfam13676 76 LADPEGRKR--LIPVRL 90
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
389-580 |
4.22e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.10 E-value: 4.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 389 TLDLRDNALKAI--GFIPSIQMVLLGGNKLVHLPH-IHFTANFLELSENRLENLSDlyfllRVPQ-LQFLILNQNRLSsC 464
Cdd:PRK15370 203 TLILDNNELKSLpeNLQGNIKTLYANSNQLTSIPAtLPDTIQEMELSINRITELPE-----RLPSaLQSLDLFHNKIS-C 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 465 KAAHTPSEnpsLEQLFLTENMLqlaweTGLCWDVFQGLSRLqilYLSNNYLNFLPPGIfndLVALRMLSLSANKLTVLsP 544
Cdd:PRK15370 277 LPENLPEE---LRYLSVYDNSI-----RTLPAHLPSGITHL---NVQSNSLTALPETL---PPGLKTLEAGENALTSL-P 341
|
170 180 190
....*....|....*....|....*....|....*.
gi 1883538051 545 GSLPANLEILDISRNQLFSPDPALFSSLRVLDITHN 580
Cdd:PRK15370 342 ASLPPELQVLDVSKNQITVLPETLPPTITTLDVSRN 377
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
291-582 |
5.53e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.86 E-value: 5.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 291 VLQLDLSHGFIFSLNPRLFGTLKDLKMLNLAFNKINKIGENAFYGLDSLQVLNL-SYNLLGELyNSNFYGLPRVAYVDLQ 369
Cdd:PLN00113 286 LISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLwSNKFSGEI-PKNLGKHNNLTVLDLS 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 370 RNHI-GIIQD------QTFRLLktLQTLDLRDNALKAIGFIPSIQMVLLGGNKLVHLPHIHFT----ANFLELSENRLE- 437
Cdd:PLN00113 365 TNNLtGEIPEglcssgNLFKLI--LFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTklplVYFLDISNNNLQg 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 438 NLSDLYFllRVPQLQFLILNQNRLSSCKAAHTPSENpsLEQLFLTENMLqlaweTGLCWDVFQGLSRLQILYLSNNYLNF 517
Cdd:PLN00113 443 RINSRKW--DMPSLQMLSLARNKFFGGLPDSFGSKR--LENLDLSRNQF-----SGAVPRKLGSLSELMQLKLSENKLSG 513
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1883538051 518 LPPGIFNDLVALRMLSLSANKLTvlspGSLPAN------LEILDISRNQLFSPDPALF---SSLRVLDITHNEF 582
Cdd:PLN00113 514 EIPDELSSCKKLVSLDLSHNQLS----GQIPASfsempvLSQLDLSQNQLSGEIPKNLgnvESLVQVNISHNHL 583
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
79-542 |
6.91e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 55.71 E-value: 6.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 79 GTQYANLTIGPGAFRNLPNLRILDLGQSQIEVLNRDAFQGLPHLLELRLFSCGLSSAVLSDGYFRNLYSLARLDLSGNQi 158
Cdd:COG4886 29 LLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 159 hslrlhsSFRELNSLSDVNFAFNQIFTIcEDELEPLQgktlsffglkltklfsrvsvgwetcrnpfrgvRLETLDLSENg 238
Cdd:COG4886 108 -------ELSNLTNLESLDLSGNQLTDL-PEELANLT--------------------------------NLKELDLSNN- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 239 wtvditrnfsniiqgsQISSLilkhhimgpgfgfqnirdpdqstfaslarssvlqldlshgfifslnPRLFGTLKDLKML 318
Cdd:COG4886 147 ----------------QLTDL----------------------------------------------PEPLGNLTNLKSL 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 319 NLAFNKINKIGEnAFYGLDSLQVLNLSYNLLGELyNSNFYGLPRVAYVDLQRNHIGIIqDQTFRLLKTLQTLDLRDNALK 398
Cdd:COG4886 165 DLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLT 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 399 AIGFI---PSIQMVLLGGNKLVHLPHIHFTAN--FLELSENRLENLSDLYFLLRVPQLQFLILNQNRLSSCKAAHTPSEN 473
Cdd:COG4886 242 DLPELgnlTNLEELDLSNNQLTDLPPLANLTNlkTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLT 321
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1883538051 474 PSLEQLFLTENMLQLAWETGLCWDVFQGLSRLQILYLSNNYLNFLPPGIFNDLVALRMLSLSANKLTVL 542
Cdd:COG4886 322 TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
85-132 |
1.74e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.67 E-value: 1.74e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1883538051 85 LTIGPGAFRNLPNLRILDLGQSQIEVLNRDAFQGLPHLLELRLFSCGL 132
Cdd:pfam13855 14 TSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
84-319 |
2.67e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 53.78 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 84 NLTIGPGAFRNLPNLRILDLGQSQIEVLNrDAFQGLPHLLELRLFSCGLSSAvlsdGYFRNLYSLARLDLSGNQIHSLrl 163
Cdd:COG4886 193 QITDLPEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDL----PELGNLTNLEELDLSNNQLTDL-- 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 164 hSSFRELNSLSDVNFAFNQIFTICEDELEPLQGKTlsffglKLTKLFSRVSVGWETCRNPFRGVRLETLDLSENGWTVDI 243
Cdd:COG4886 266 -PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN------SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLT 338
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 244 TRNFSNIIQGSQISSLILKHHIMGPGFGFQNIRDPDQSTFASLARSSVLQLDLSHGFIFSLNPRLFGTLKDLKMLN 319
Cdd:COG4886 339 TLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
402-581 |
5.41e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.55 E-value: 5.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 402 FIP-SIQMVLLGGNKLVHLPHiHFTANFLELSENrlENLsdlyfLLRVPQ-----LQFLILNQNRLSSCkAAHTPSenpS 475
Cdd:PRK15370 196 CIPeQITTLILDNNELKSLPE-NLQGNIKTLYAN--SNQ-----LTSIPAtlpdtIQEMELSINRITEL-PERLPS---A 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 476 LEQLFLTENMLqlaweTGLCWDVFQGLsrlQILYLSNNYLNFLPPGIFNDLVALRMLSlsaNKLTVLsPGSLPANLEILD 555
Cdd:PRK15370 264 LQSLDLFHNKI-----SCLPENLPEEL---RYLSVYDNSIRTLPAHLPSGITHLNVQS---NSLTAL-PETLPPGLKTLE 331
|
170 180
....*....|....*....|....*.
gi 1883538051 556 ISRNQLFSPDPALFSSLRVLDITHNE 581
Cdd:PRK15370 332 AGENALTSLPASLPPELQVLDVSKNQ 357
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
498-583 |
5.88e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.31 E-value: 5.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 498 VFQGLSRLQILYLSNNYLNF-LPPGIFNDLVALRMLSLSANKLTVLSPGSLPANLEILDISRNQLFSPDPA---LFSSLR 573
Cdd:PLN00113 88 AIFRLPYIQTINLSNNQLSGpIPDDIFTTSSSLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPNdigSFSSLK 167
|
90
....*....|
gi 1883538051 574 VLDITHNEFV 583
Cdd:PLN00113 168 VLDLGGNVLV 177
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
339-581 |
7.81e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 51.97 E-value: 7.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 339 LQVLNLSYNLLGELynsnfyGLPRVAYVdlqrnhigiIQDQtfrllKTLQTLDLRDNALKAIG-FIPSIQMVLLGGNKLV 417
Cdd:cd00116 25 LQVLRLEGNTLGEE------AAKALASA---------LRPQ-----PSLKELCLSLNETGRIPrGLQSLLQGLTKGCGLQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 418 HLPhiHFTANFLELSENRLENlsdlyfLLRVPQLQFLILNQNRLSSCKAAHT----PSENPSLEQLFLTENMLqlawETG 493
Cdd:cd00116 85 ELD--LSDNALGPDGCGVLES------LLRSSSLQELKLNNNGLGDRGLRLLakglKDLPPALEKLVLGRNRL----EGA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 494 LCWD---VFQGLSRLQILYLSNNylNFLPPGI------FNDLVALRMLSLSANKLTVLSPGSL------PANLEILDISR 558
Cdd:cd00116 153 SCEAlakALRANRDLKELNLANN--GIGDAGIralaegLKANCNLEVLDLNNNGLTDEGASALaetlasLKSLEVLNLGD 230
|
250 260 270
....*....|....*....|....*....|.
gi 1883538051 559 NQLFSPD--------PALFSSLRVLDITHNE 581
Cdd:cd00116 231 NNLTDAGaaalasalLSPNISLLTLSLSCND 261
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
491-584 |
1.88e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 51.62 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 491 ETGLCWDVFqGLSRL------QI--LYLSNNYLNFLPPGIFNDLvalRMLSLSANKLTVLsPGSLPANLEILDISRNQLF 562
Cdd:PRK15370 180 KTELRLKIL-GLTTIpacipeQIttLILDNNELKSLPENLQGNI---KTLYANSNQLTSI-PATLPDTIQEMELSINRIT 254
|
90 100
....*....|....*....|..
gi 1883538051 563 SPDPALFSSLRVLDITHNEFVC 584
Cdd:PRK15370 255 ELPERLPSALQSLDLFHNKISC 276
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
338-397 |
5.43e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.44 E-value: 5.43e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 338 SLQVLNLSYNLLGELYNSNFYGLPRVAYVDLQRNHIGIIQDQTFRLLKTLQTLDLRDNAL 397
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
429-582 |
1.71e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 46.70 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 429 LELSENRLENLSDLYFLlrvPQLQFLILNQNRLSSCKAAHTpseNPSLEQLFLTENMLQlawetglCWDVFQGLSRLQIL 508
Cdd:cd21340 7 LYLNDKNITKIDNLSLC---KNLKVLYLYDNKITKIENLEF---LTNLTHLYLQNNQIE-------KIENLENLVNLKKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 509 YLSNNYLNFLpPGiFNDLVALRMLSLSANKLT-----VLSPGSLPA---NLEILDISRNQLFSPDP-ALFSSLRVLDITH 579
Cdd:cd21340 74 YLGGNRISVV-EG-LENLTNLEELHIENQRLPpgeklTFDPRSLAAlsnSLRVLNISGNNIDSLEPlAPLRNLEQLDASN 151
|
...
gi 1883538051 580 NEF 582
Cdd:cd21340 152 NQI 154
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
555-633 |
3.30e-05 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 47.77 E-value: 3.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 555 DISRNQLFSPDPALFS---SLRVLDITHNEFVCNCELSTFISWLNQTNVTLFgSPADVYCMYPNSLLGGSLYNIS--TED 629
Cdd:TIGR00864 1 DISNNKISTIEEGICAnlcNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVR-QPEAALCAGPGALAGQPLLGIPllDSG 79
|
....
gi 1883538051 630 CDEE 633
Cdd:TIGR00864 80 CDEE 83
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
408-582 |
6.65e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 46.08 E-value: 6.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 408 MVLLGGNKLVHLPHIHFTANFLELSENRLENLSDLYFLLRVPQLQFLILNQNRLSSCKAAHTPSENPSLEQLFLTENMLQ 487
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 488 LAWETGLCWDVFQGLSRLQIL-----------------YLSNNYLNFLPPGIFNdLVALRMLSLSANKLTVLSP--GSLP 548
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELdlsgneelsnltnleslDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDLPEplGNLT 159
|
170 180 190
....*....|....*....|....*....|....*.
gi 1883538051 549 aNLEILDISRNQLFSPDPALF--SSLRVLDITHNEF 582
Cdd:COG4886 160 -NLKSLDLSNNQLTDLPEELGnlTNLKELDLSNNQI 194
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
361-416 |
2.90e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 2.90e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1883538051 361 PRVAYVDLQRNHIGIIQDQTFRLLKTLQTLDLRDNALK-----AIGFIPSIQMVLLGGNKL 416
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTtlspgAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
387-606 |
3.20e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 44.38 E-value: 3.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 387 LQTLDLRDNALKAIGFIPS-IQMVLLGGNKLVHLPHIHFTANFLELSENRLENLSDLyfllrVPQLQFLILNQNRLSSck 465
Cdd:PRK15387 264 LLELSIFSNPLTHLPALPSgLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPAL-----PSELCKLWAYNNQLTS-- 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 466 aahTPSENPSLEQLFLTENmlQLAWETGLCWDVFQglsrlqiLYLSNNYLNFLP--PGifndlvALRMLSLSANKLTVLS 543
Cdd:PRK15387 337 ---LPTLPSGLQELSVSDN--QLASLPTLPSELYK-------LWAYNNRLTSLPalPS------GLKELIVSGNRLTSLP 398
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1883538051 544 pgSLPANLEILDISRNQLFSPdPALFSSLRVLDITHNEFVCNCElsTFISWLNQTNVTLFGSP 606
Cdd:PRK15387 399 --VLPSELKELMVSGNRLTSL-PMLPSGLLSLSVYRNQLTRLPE--SLIHLSSETTVNLEGNP 456
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
449-515 |
3.89e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.04 E-value: 3.89e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1883538051 449 PQLQFLILNQNRLSSCKAaHTPSENPSLEQLFLTENMLqlaweTGLCWDVFQGLSRLQILYLSNNYL 515
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDD-GAFKGLSNLKVLDLSNNLL-----TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
96-183 |
1.17e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.89 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 96 PNLRILDLGQSQIEVLNRDAFQGLPHLLELrlfscglssavlsdgyfrnlyslarlDLSGNQIHSLRLHsSFRELNSLSD 175
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVL--------------------------DLSNNLLTTLSPG-AFSGLPSLRY 53
|
....*...
gi 1883538051 176 VNFAFNQI 183
Cdd:pfam13855 54 LDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
92-181 |
1.50e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.92 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 92 FRNLPNLRILDLGQSQIEVLNrdAFQGLPHLLELRL------------FSCGLSSAVL--------------SDGYFRNL 145
Cdd:cd21340 64 LENLVNLKKLYLGGNRISVVE--GLENLTNLEELHIenqrlppgekltFDPRSLAALSnslrvlnisgnnidSLEPLAPL 141
|
90 100 110
....*....|....*....|....*....|....*..
gi 1883538051 146 YSLARLDLSGNQIHSLR-LHSSFRELNSLSDVNFAFN 181
Cdd:cd21340 142 RNLEQLDASNNQISDLEeLLDLLSSWPSLRELDLTGN 178
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
443-561 |
4.07e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 40.42 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1883538051 443 YFLLRVPQLQFLILNQNRLS------SCKAAHTPsenPSLEQLFLTENMLQLAWE-TGLCWDVFQGLSRLQILYLSNNYL 515
Cdd:cd00116 17 ELLPKLLCLQVLRLEGNTLGeeaakaLASALRPQ---PSLKELCLSLNETGRIPRgLQSLLQGLTKGCGLQELDLSDNAL 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1883538051 516 NFLPPGIFNDL---VALRMLSLSANKLTVL-------SPGSLPANLEILDISRNQL 561
Cdd:cd00116 94 GPDGCGVLESLlrsSSLQELKLNNNGLGDRglrllakGLKDLPPALEKLVLGRNRL 149
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
580-631 |
9.38e-03 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 35.10 E-value: 9.38e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1883538051 580 NEFVCNCELSTFISWLNQTNVtlFGSPADVYCMYPNSLLGGSL-YNISTEDCD 631
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEH--LQDPVDLRCASPSSLRGPLLeLLHSEFKCP 51
|
|
| |
