C-X-C motif chemokine 14 precursor [Mus musculus]
Protein Classification
CC/CxC family chemokine( domain architecture ID 10441213)
CC/CxC family chemokine similar to human C-X-C motif chemokine 14, which is preferentially expressed in normal vs malignant tissue and as a chemokine is involved in the regulation of leukocyte infiltration into inflamed tissue and may affect disease processes
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| IL8 | pfam00048 | Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted ... |
33-86 | 4.17e-06 | ||
Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds. : Pssm-ID: 459650 Cd Length: 60 Bit Score: 40.71 E-value: 4.17e-06
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| Name | Accession | Description | Interval | E-value | ||
| IL8 | pfam00048 | Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted ... |
33-86 | 4.17e-06 | ||
Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds. Pssm-ID: 459650 Cd Length: 60 Bit Score: 40.71 E-value: 4.17e-06
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| Chemokine_CXC | cd00273 | Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal ... |
24-85 | 5.02e-05 | ||
Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members contain an RCxC motif which may be a general requirement for binding to CXC chemokine receptors; those with the ELR motif are chemotatic for neutrophils and have been shown to be angiogenic, while those without the motif act on T and B cells, and are typically angiostatic; exist as monomers and dimers, but are believed to be functional as monomers; found only in vertebrates and a few viruses. See CDs: Chemokine (cd00169) for the general alignment of chemokines, or Chemokine_CC (cd00272), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for the additional chemokine subgroups. Pssm-ID: 238171 Cd Length: 64 Bit Score: 38.01 E-value: 5.02e-05
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| Name | Accession | Description | Interval | E-value | ||
| IL8 | pfam00048 | Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted ... |
33-86 | 4.17e-06 | ||
Small cytokines (intecrine/chemokine), interleukin-8 like; Includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity. Structure contains two highly conserved disulfide bonds. Pssm-ID: 459650 Cd Length: 60 Bit Score: 40.71 E-value: 4.17e-06
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| Chemokine_CXC | cd00273 | Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal ... |
24-85 | 5.02e-05 | ||
Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members contain an RCxC motif which may be a general requirement for binding to CXC chemokine receptors; those with the ELR motif are chemotatic for neutrophils and have been shown to be angiogenic, while those without the motif act on T and B cells, and are typically angiostatic; exist as monomers and dimers, but are believed to be functional as monomers; found only in vertebrates and a few viruses. See CDs: Chemokine (cd00169) for the general alignment of chemokines, or Chemokine_CC (cd00272), Chemokine_C (cd00271), and Chemokine_CX3C (cd00274) for the additional chemokine subgroups. Pssm-ID: 238171 Cd Length: 64 Bit Score: 38.01 E-value: 5.02e-05
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