NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|226958528|ref|NP_062758|]
View 

uncharacterized protein LOC80384 isoform 1 [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK03918 super family cl35229
DNA double-strand break repair ATPase Rad50;
78-214 2.58e-03

DNA double-strand break repair ATPase Rad50;


The actual alignment was detected with superfamily member PRK03918:

Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.82  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528  78 SMLVKNKTLLAELRNLQSKLyvKETSLQEVKA---ELESYKERNAQQELQIISLRDDIKSLQDLIDSLMKMKILKNtnsq 154
Cdd:PRK03918 493 SELIKLKELAEQLKELEEKL--KKYNLEELEKkaeEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD---- 566
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528 155 nfgrhnwDLTERVLDLENRLREhlVGREEIKaELLEKRRSCPSSFSPYMNLKGPEDSLDI 214
Cdd:PRK03918 567 -------ELEEELAELLKELEE--LGFESVE-ELEERLKELEPFYNEYLELKDAEKELER 616
 
Name Accession Description Interval E-value
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
78-214 2.58e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.82  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528  78 SMLVKNKTLLAELRNLQSKLyvKETSLQEVKA---ELESYKERNAQQELQIISLRDDIKSLQDLIDSLMKMKILKNtnsq 154
Cdd:PRK03918 493 SELIKLKELAEQLKELEEKL--KKYNLEELEKkaeEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD---- 566
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528 155 nfgrhnwDLTERVLDLENRLREhlVGREEIKaELLEKRRSCPSSFSPYMNLKGPEDSLDI 214
Cdd:PRK03918 567 -------ELEEELAELLKELEE--LGFESVE-ELEERLKELEPFYNEYLELKDAEKELER 616
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
84-192 9.27e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 37.98  E-value: 9.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528  84 KTLLAELRNLQSKLYVKETSLQEVKAELESYKERNAQQELQIISLRDDIKSLQDLIDSLMKMKILKNTNSQNFgrhnwDL 163
Cdd:COG1579   27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEIE-----SL 101
                         90       100
                 ....*....|....*....|....*....
gi 226958528 164 TERVLDLENRLREHLVGREEIKAELLEKR 192
Cdd:COG1579  102 KRRISDLEDEILELMERIEELEEELAELE 130
 
Name Accession Description Interval E-value
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
78-214 2.58e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 40.82  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528  78 SMLVKNKTLLAELRNLQSKLyvKETSLQEVKA---ELESYKERNAQQELQIISLRDDIKSLQDLIDSLMKMKILKNtnsq 154
Cdd:PRK03918 493 SELIKLKELAEQLKELEEKL--KKYNLEELEKkaeEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD---- 566
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528 155 nfgrhnwDLTERVLDLENRLREhlVGREEIKaELLEKRRSCPSSFSPYMNLKGPEDSLDI 214
Cdd:PRK03918 567 -------ELEEELAELLKELEE--LGFESVE-ELEERLKELEPFYNEYLELKDAEKELER 616
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
84-192 9.27e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 37.98  E-value: 9.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226958528  84 KTLLAELRNLQSKLYVKETSLQEVKAELESYKERNAQQELQIISLRDDIKSLQDLIDSLMKMKILKNTNSQNFgrhnwDL 163
Cdd:COG1579   27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEALQKEIE-----SL 101
                         90       100
                 ....*....|....*....|....*....
gi 226958528 164 TERVLDLENRLREHLVGREEIKAELLEKR 192
Cdd:COG1579  102 KRRISDLEDEILELMERIEELEEELAELE 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH