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Conserved domains on  [gi|10946614|ref|NP_067287|]
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ribosome biogenesis protein WDR12 [Mus musculus]

Protein Classification

WDR12/YTM1 family ribosome biogenesis protein( domain architecture ID 10548159)

WDR12/YTM1 family ribosome biogenesis protein is required for maturation of ribosomal RNAs and the formation of the ribosome

CATH:  2.130.10.10
Gene Ontology:  GO:0042273|GO:0005515
PubMed:  10322433|18448671|17353269

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
100-409 6.67e-56

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 189.74  E-value: 6.67e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSI----EGaeEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWewNV 174
Cdd:COG2319 119 HTGAVRSVafspDG--KTLASGSADGTVRLWDLAtGKLLRTLTGHSGAVTSVAFSPDGKL---LASGSDDGTVRLW--DL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 175 EKNKVkaLHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVptdeedemeeatnrprkkqkteqlglTRTPLVTLS 254
Cdd:COG2319 192 ATGKL--LRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA--------------------------TGKLLRTLT 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 255 GHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPRTkdGS 332
Cdd:COG2319 244 GHSGSVRSVAFSpDGRLLASGSADGTVRLWDLATGELLRTLTGHSgGVNSVAFSPDGKLLASGSDDGTVRLWDLAT--GK 321

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 10946614 333 LVSlSLTSHTGWVTSVKWSPThEQQLISGSLDNIVKLWDTRScKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:COG2319 322 LLR-TLTGHTGAVRSVAFSPD-GKTLASGSDDGTVRLWDLAT-GELLRTLTGHTGAVTSVAFSPDGrTLASGSADGTV 396
NLE pfam08154
NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the ...
 4-70 4.91e-21

NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the microtubule-associated protein Swiss:Q12024.


:

Pssm-ID: 462380  Cd Length: 66  Bit Score: 86.04  E-value: 4.91e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 10946614     4 LQARFYSENKKYAVDDVPFSIPAAAEVADLSNIINKLLETKnELHKHVEFDFLIKGQFLRVPLVKHM 70
Cdd:pfam08154   1 VQVRFVTKEGELAVPGTPLDVPVSLTRYQLSELVNSLLKNE-ELEKPVPFDFLINGEFLRTSLEEHL 66
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
100-409 6.67e-56

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 189.74  E-value: 6.67e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSI----EGaeEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWewNV 174
Cdd:COG2319 119 HTGAVRSVafspDG--KTLASGSADGTVRLWDLAtGKLLRTLTGHSGAVTSVAFSPDGKL---LASGSDDGTVRLW--DL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 175 EKNKVkaLHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVptdeedemeeatnrprkkqkteqlglTRTPLVTLS 254
Cdd:COG2319 192 ATGKL--LRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA--------------------------TGKLLRTLT 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 255 GHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPRTkdGS 332
Cdd:COG2319 244 GHSGSVRSVAFSpDGRLLASGSADGTVRLWDLATGELLRTLTGHSgGVNSVAFSPDGKLLASGSDDGTVRLWDLAT--GK 321

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 10946614 333 LVSlSLTSHTGWVTSVKWSPThEQQLISGSLDNIVKLWDTRScKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:COG2319 322 LLR-TLTGHTGAVRSVAFSPD-GKTLASGSDDGTVRLWDLAT-GELLRTLTGHTGAVTSVAFSPDGrTLASGSADGTV 396
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 100-409 3.62e-54

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 181.76  E-value: 3.62e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSI--EGAEEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVkkdSLSCLLLTASMDQTVLLWEWnvek 176
Cdd:cd00200   8 HTGGVTCVafSPDGKLLATGSGDGTIKVWDLEtGELLRTLKGHTGPVRDVAAS---ADGTYLASGSSDKTIRLWDL---- 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 177 NKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeatnrprkkqkteqlgLTRTPLVTLSGH 256
Cdd:cd00200  81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDV--------------------------ETGKCLTTLRGH 134

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 257 TEAISSVLWSDAEE-ICSASWDHTIRVWDVESGGLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWDPRTKDgslV 334
Cdd:cd00200 135 TDWVNSVAFSPDGTfVASSSQDGTIKLWDLRTGKCVATLTGHTGEvNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK---C 211

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 10946614 335 SLSLTSHTGWVTSVKWSPtHEQQLISGSLDNIVKLWDTRSCKaPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:cd00200 212 LGTLRGHENGVNSVAFSP-DGYLLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLAWSPDGkRLASGSADGTI 285
NLE pfam08154
NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the ...
 4-70 4.91e-21

NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the microtubule-associated protein Swiss:Q12024.


Pssm-ID: 462380  Cd Length: 66  Bit Score: 86.04  E-value: 4.91e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 10946614     4 LQARFYSENKKYAVDDVPFSIPAAAEVADLSNIINKLLETKnELHKHVEFDFLIKGQFLRVPLVKHM 70
Cdd:pfam08154   1 VQVRFVTKEGELAVPGTPLDVPVSLTRYQLSELVNSLLKNE-ELEKPVPFDFLINGEFLRTSLEEHL 66
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 192-421 1.58e-11

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 66.26  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  192 VDAIAVDSSGAKFCSGSWDKMLKIWstvptdeedEMEEATNRPRKkqkteqlglTRTPLVTLSGHTEaISSVLWSD--AE 269
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIF---------ECESIIKDGRD---------IHYPVVELASRSK-LSGICWNSyiKS 546

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  270 EICSASWDHTIRVWDVESGGLKSTLTGNK--VFNCISYSPLCKRLASGSTDRHIRLWDPRTKdgslVSLSLTSHTGWVTS 347
Cdd:PLN00181 547 QVASSNFEGVVQVWDVARSQLVTEMKEHEkrVWSIDYSSADPTLLASGSDDGSVKLWSINQG----VSIGTIKTKANICC 622

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10946614  348 VKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYSYSPTTSHV 421
Cdd:PLN00181 623 VQFPSESGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMSISGI 696
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 337-371 1.38e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.61  E-value: 1.38e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 10946614    337 SLTSHTGWVTSVKWSPTHeQQLISGSLDNIVKLWD 371
Cdd:smart00320   7 TLKGHTGPVTSVAFSPDG-KYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
337-371 6.87e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 42.72  E-value: 6.87e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 10946614   337 SLTSHTGWVTSVKWSPTHeQQLISGSLDNIVKLWD 371
Cdd:pfam00400   6 TLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
100-409 6.67e-56

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 189.74  E-value: 6.67e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSI----EGaeEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWewNV 174
Cdd:COG2319 119 HTGAVRSVafspDG--KTLASGSADGTVRLWDLAtGKLLRTLTGHSGAVTSVAFSPDGKL---LASGSDDGTVRLW--DL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 175 EKNKVkaLHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVptdeedemeeatnrprkkqkteqlglTRTPLVTLS 254
Cdd:COG2319 192 ATGKL--LRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA--------------------------TGKLLRTLT 243

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 255 GHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPRTkdGS 332
Cdd:COG2319 244 GHSGSVRSVAFSpDGRLLASGSADGTVRLWDLATGELLRTLTGHSgGVNSVAFSPDGKLLASGSDDGTVRLWDLAT--GK 321

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 10946614 333 LVSlSLTSHTGWVTSVKWSPThEQQLISGSLDNIVKLWDTRScKAPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:COG2319 322 LLR-TLTGHTGAVRSVAFSPD-GKTLASGSDDGTVRLWDLAT-GELLRTLTGHTGAVTSVAFSPDGrTLASGSADGTV 396
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 100-409 3.62e-54

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 181.76  E-value: 3.62e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSI--EGAEEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVkkdSLSCLLLTASMDQTVLLWEWnvek 176
Cdd:cd00200   8 HTGGVTCVafSPDGKLLATGSGDGTIKVWDLEtGELLRTLKGHTGPVRDVAAS---ADGTYLASGSSDKTIRLWDL---- 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 177 NKVKALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeatnrprkkqkteqlgLTRTPLVTLSGH 256
Cdd:cd00200  81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDV--------------------------ETGKCLTTLRGH 134

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 257 TEAISSVLWSDAEE-ICSASWDHTIRVWDVESGGLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWDPRTKDgslV 334
Cdd:cd00200 135 TDWVNSVAFSPDGTfVASSSQDGTIKLWDLRTGKCVATLTGHTGEvNSVAFSPDGEKLLSSSSDGTIKLWDLSTGK---C 211

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 10946614 335 SLSLTSHTGWVTSVKWSPtHEQQLISGSLDNIVKLWDTRSCKaPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:cd00200 212 LGTLRGHENGVNSVAFSP-DGYLLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLAWSPDGkRLASGSADGTI 285
WD40 COG2319
WD40 repeat [General function prediction only];
100-410 9.59e-54

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 183.96  E-value: 9.59e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSIE--GAEEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWvkkDSLSCLLLTASMDQTVLLWewNVEK 176
Cdd:COG2319  77 HTAAVLSVAfsPDGRLLASASADGTVRLWDLAtGLLLRTLTGHTGAVRSVAF---SPDGKTLASGSADGTVRLW--DLAT 151

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 177 NKVkaLHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeatnrprkkqkteqlgLTRTPLVTLSGH 256
Cdd:COG2319 152 GKL--LRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDL--------------------------ATGKLLRTLTGH 203

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 257 TEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWDPRTkdGSLV 334
Cdd:COG2319 204 TGAVRSVAFSpDGKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASGSADGTVRLWDLAT--GELL 281

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 10946614 335 SLsLTSHTGWVTSVKWSPThEQQLISGSLDNIVKLWDTRSCKaPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKLY 410
Cdd:COG2319 282 RT-LTGHSGGVNSVAFSPD-GKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDGkTLASGSDDGTVR 355
WD40 COG2319
WD40 repeat [General function prediction only];
100-374 3.15e-50

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 174.71  E-value: 3.15e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSIE----GaeEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWewNV 174
Cdd:COG2319 161 HSGAVTSVAfspdG--KLLASGSDDGTVRLWDLAtGKLLRTLTGHTGAVRSVAFSPDGKL---LASGSADGTVRLW--DL 233

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 175 EKNKVKALHccRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTVptdeedemeeatnrprkkqkteqlglTRTPLVTLS 254
Cdd:COG2319 234 ATGKLLRTL--TGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLA--------------------------TGELLRTLT 285

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 255 GHTEAISSVLWS-DAEEICSASWDHTIRVWDVESGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKdgs 332
Cdd:COG2319 286 GHSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG--- 362

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 10946614 333 LVSLSLTSHTGWVTSVKWSPtHEQQLISGSLDNIVKLWDTRS 374
Cdd:COG2319 363 ELLRTLTGHTGAVTSVAFSP-DGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 135-413 1.27e-48

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 167.13  E-value: 1.27e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 135 TIVGHTDVVKDVAWvkkDSLSCLLLTASMDQTVLLWewNVEKNKVkaLHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLK 214
Cdd:cd00200   4 TLKGHTGGVTCVAF---SPDGKLLATGSGDGTIKVW--DLETGEL--LRTLKGHTGPVRDVAASADGTYLASGSSDKTIR 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 215 IWSTVptdeedemeeatnrprkkqkteqlglTRTPLVTLSGHTEAISSVLWSDAEEI-CSASWDHTIRVWDVESGGLKST 293
Cdd:cd00200  77 LWDLE--------------------------TGECVRTLTGHTSYVSSVAFSPDGRIlSSSSRDKTIKVWDVETGKCLTT 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 294 LTGNKVF-NCISYSPLCKRLASGSTDRHIRLWDPRTkdGSLVSlSLTSHTGWVTSVKWSPThEQQLISGSLDNIVKLWDT 372
Cdd:cd00200 131 LRGHTDWvNSVAFSPDGTFVASSSQDGTIKLWDLRT--GKCVA-TLTGHTGEVNSVAFSPD-GEKLLSSSSDGTIKLWDL 206

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 10946614 373 RScKAPLYDLAAHEDKVLSVDWTDTGLLL-SGGADNKLYSYS 413
Cdd:cd00200 207 ST-GKCLGTLRGHENGVNSVAFSPDGYLLaSGSEDGTIRVWD 247
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 112-371 1.28e-46

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 162.12  E-value: 1.28e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 112 EWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWEWNveknKVKALHCCRGHAG 190
Cdd:cd00200  64 TYLASGSSDKTIRLWDLEtGECVRTLTGHTSYVSSVAFSPDGRI---LSSSSRDKTIKVWDVE----TGKCLTTLRGHTD 136

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 191 SVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeATNRPRKkqkteqlgltrtplvTLSGHTEAISSVLWS-DAE 269
Cdd:cd00200 137 WVNSVAFSPDGTFVASSSQDGTIKLWDL-----------RTGKCVA---------------TLTGHTGEVNSVAFSpDGE 190

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 270 EICSASWDHTIRVWDVESGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDgslVSLSLTSHTGWVTSV 348
Cdd:cd00200 191 KLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGE---CVQTLSGHTNSVTSL 267

                       250       260
                ....*....|....*....|...
gi 10946614 349 KWSPThEQQLISGSLDNIVKLWD 371
Cdd:cd00200 268 AWSPD-GKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
109-409 1.13e-38

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 143.90  E-value: 1.13e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 109 GAEEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWEWNVEKnkvkALHCCRG 187
Cdd:COG2319   4 ADGAALAAASADLALALLAAAlGALLLLLLGLAAAVASLAASPDGAR---LAAGAGDLTLLLLDAAAGA----LLATLLG 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 188 HAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeatnrprkkqkteqlgLTRTPLVTLSGHTEAISSVLWS- 266
Cdd:COG2319  77 HTAAVLSVAFSPDGRLLASASADGTVRLWDL--------------------------ATGLLLRTLTGHTGAVRSVAFSp 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 267 DAEEICSASWDHTIRVWDVESGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWDPRTkdGSLVsLSLTSHTGWV 345
Cdd:COG2319 131 DGKTLASGSADGTVRLWDLATGKLLRTLTGhSGAVTSVAFSPDGKLLASGSDDGTVRLWDLAT--GKLL-RTLTGHTGAV 207

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 10946614 346 TSVKWSPtHEQQLISGSLDNIVKLWDTRSCKaPLYDLAAHEDKVLSVDWTDTG-LLLSGGADNKL 409
Cdd:COG2319 208 RSVAFSP-DGKLLASGSADGTVRLWDLATGK-LLRTLTGHSGSVRSVAFSPDGrLLASGSADGTV 270
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 100-325 2.28e-33

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 126.68  E-value: 2.28e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 100 HDDWISSIE--GAEEWILSGSYDKTSRIWSLE-GKSIMTIVGHTDVVKDVAWVKKDSLsclLLTASMDQTVLLWewNVEK 176
Cdd:cd00200  92 HTSYVSSVAfsPDGRILSSSSRDKTIKVWDVEtGKCLTTLRGHTDWVNSVAFSPDGTF---VASSSQDGTIKLW--DLRT 166

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614 177 NKVKALHccRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWSTvptdeedemeeatnrprkkqkteqlgLTRTPLVTLSGH 256
Cdd:cd00200 167 GKCVATL--TGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL--------------------------STGKCLGTLRGH 218

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 10946614 257 TEAISSVLWSDAEEI-CSASWDHTIRVWDVESGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWD 325
Cdd:cd00200 219 ENGVNSVAFSPDGYLlASGSEDGTIRVWDLRTGECVQTLSGhTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
NLE pfam08154
NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the ...
 4-70 4.91e-21

NLE (NUC135) domain; This domain is located N terminal to WD40 repeats. It is found in the microtubule-associated protein Swiss:Q12024.


Pssm-ID: 462380  Cd Length: 66  Bit Score: 86.04  E-value: 4.91e-21
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 10946614     4 LQARFYSENKKYAVDDVPFSIPAAAEVADLSNIINKLLETKnELHKHVEFDFLIKGQFLRVPLVKHM 70
Cdd:pfam08154   1 VQVRFVTKEGELAVPGTPLDVPVSLTRYQLSELVNSLLKNE-ELEKPVPFDFLINGEFLRTSLEEHL 66
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 192-421 1.58e-11

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 66.26  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  192 VDAIAVDSSGAKFCSGSWDKMLKIWstvptdeedEMEEATNRPRKkqkteqlglTRTPLVTLSGHTEaISSVLWSD--AE 269
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIF---------ECESIIKDGRD---------IHYPVVELASRSK-LSGICWNSyiKS 546

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  270 EICSASWDHTIRVWDVESGGLKSTLTGNK--VFNCISYSPLCKRLASGSTDRHIRLWDPRTKdgslVSLSLTSHTGWVTS 347
Cdd:PLN00181 547 QVASSNFEGVVQVWDVARSQLVTEMKEHEkrVWSIDYSSADPTLLASGSDDGSVKLWSINQG----VSIGTIKTKANICC 622

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 10946614  348 VKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYSYSPTTSHV 421
Cdd:PLN00181 623 VQFPSESGRSLAFGSADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMSISGI 696
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 337-371 1.38e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.61  E-value: 1.38e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 10946614    337 SLTSHTGWVTSVKWSPTHeQQLISGSLDNIVKLWD 371
Cdd:smart00320   7 TLKGHTGPVTSVAFSPDG-KYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 246-284 2.09e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.23  E-value: 2.09e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 10946614    246 TRTPLVTLSGHTEAISSVLWS-DAEEICSASWDHTIRVWD 284
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSpDGKYLASGSDDGTIKLWD 40
PTZ00420 PTZ00420
coronin; Provisional
 283-408 3.65e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 49.18  E-value: 3.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  283 WDVESGGLKSTLT-GNKVFNC--------------ISYSP-LCKRLASGSTDRHIRLWDPRTKDGSLVSLS-----LTSH 341
Cdd:PTZ00420  45 WEVEGGGLIGAIRlENQMRKPpviklkghtssildLQFNPcFSEILASGSEDLTIRVWEIPHNDESVKEIKdpqciLKGH 124

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 10946614  342 TGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAheDKVLSVDWTDTGLLLSGGADNK 408
Cdd:PTZ00420 125 KKKISIIDWNPMNYYIMCSSGFDSFVNIWDIENEKRAFQINMP--KKLSSLKWNIKGNLLSGTCVGK 189
PTZ00421 PTZ00421
coronin; Provisional
 244-422 6.19e-06

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 48.35  E-value: 6.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  244 GLTRT---PLVTLSGHTE--AISSVLWSDAEEICSASWDHTIRVWDVESGGLKSTLTgnkvfnCISY-----------SP 307
Cdd:PTZ00421 109 GLTQNisdPIVHLQGHTKkvGIVSFHPSAMNVLASAGADMVVNVWDVERGKAVEVIK------CHSDqitslewnldgSL 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  308 LCkrlaSGSTDRHIRLWDPRtkDGSLVSLSLTSHTGWVTSVKWSptHEQQLI-----SGSLDNIVKLWDTRSCKAPLY-- 380
Cdd:PTZ00421 183 LC----TTSKDKKLNIIDPR--DGTIVSSVEAHASAKSQRCLWA--KRKDLIitlgcSKSQQRQIMLWDTRKMASPYStv 254

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 10946614  381 DLAAHEDKVLSVDWTDTGLLLSGG-----------ADNKL-YSYSYSPTTSHVG 422
Cdd:PTZ00421 255 DLDQSSALFIPFFDEDTNLLYIGSkgegnircfelMNERLtFCSSYSSVEPHKG 308
WD40 pfam00400
WD domain, G-beta repeat;
337-371 6.87e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 42.72  E-value: 6.87e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 10946614   337 SLTSHTGWVTSVKWSPTHeQQLISGSLDNIVKLWD 371
Cdd:pfam00400   6 TLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
247-284 1.16e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 1.16e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 10946614   247 RTPLVTLSGHTEAISSVLWS-DAEEICSASWDHTIRVWD 284
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSpDGKLLASGSDDGTVKVWD 39
PTZ00420 PTZ00420
coronin; Provisional
 206-379 1.01e-04

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 44.56  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  206 SGSWDKMLKIWStVPTDEEDEMEeatnrprkkqkteqlglTRTPLVTLSGHTEAISSVLWSDAEE--ICSASWDHTIRVW 283
Cdd:PTZ00420  92 SGSEDLTIRVWE-IPHNDESVKE-----------------IKDPQCILKGHKKKISIIDWNPMNYyiMCSSGFDSFVNIW 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  284 DVESGGLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDgslVSLSLTSHTG-------WVTSVKWSPTHeq 356
Cdd:PTZ00420 154 DIENEKRAFQINMPKKLSSLKWNIKGNLLSGTCVGKHMHIIDPRKQE---IASSFHIHDGgkntkniWIDGLGGDDNY-- 228

                        170       180
                 ....*....|....*....|....*.
gi 10946614  357 QLISG-SLDNI--VKLWDTRSCKAPL 379
Cdd:PTZ00420 229 ILSTGfSKNNMreMKLWDLKNTTSAL 254
PTZ00421 PTZ00421
coronin; Provisional
 267-376 3.36e-04

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 42.96  E-value: 3.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10946614  267 DAEEICSASWDHTIRVWDVESGGLKST-------LTG-NKVFNCISYSPLCKR-LASGSTDRHIRLWDPRTkdGSLVSlS 337
Cdd:PTZ00421  87 DPQKLFTASEDGTIMGWGIPEEGLTQNisdpivhLQGhTKKVGIVSFHPSAMNvLASAGADMVVNVWDVER--GKAVE-V 163

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 10946614  338 LTSHTGWVTSVKWSpTHEQQLISGSLDNIVKLWDTRSCK 376
Cdd:PTZ00421 164 IKCHSDQITSLEWN-LDGSLLCTTSKDKKLNIIDPRDGT 201
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 180-217 4.41e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.68  E-value: 4.41e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 10946614    180 KALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWS 217
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 130-171 5.53e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 37.29  E-value: 5.53e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 10946614    130 GKSIMTIVGHTDVVKDVAWvkkDSLSCLLLTASMDQTVLLWE 171
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAF---SPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
180-217 5.84e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 37.32  E-value: 5.84e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 10946614   180 KALHCCRGHAGSVDAIAVDSSGAKFCSGSWDKMLKIWS 217
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 287-325 6.87e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 36.91  E-value: 6.87e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 10946614    287 SGGLKSTLTG-NKVFNCISYSPLCKRLASGSTDRHIRLWD 325
Cdd:smart00320   1 SGELLKTLKGhTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
130-171 3.24e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 35.01  E-value: 3.24e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 10946614   130 GKSIMTIVGHTDVVKDVAWvkkDSLSCLLLTASMDQTVLLWE 171
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAF---SPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
288-325 4.44e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 34.63  E-value: 4.44e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 10946614   288 GGLKSTLTGNKVF-NCISYSPLCKRLASGSTDRHIRLWD 325
Cdd:pfam00400   1 GKLLKTLEGHTGSvTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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