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Conserved domains on  [gi|17149853|ref|NP_071393|]
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FK506-binding protein-like [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
200-338 5.55e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 5.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 200 ELETSEKEALAReeraRGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVL 279
Cdd:COG0457   2 ELDPDDAEAYNN----LGLAYRRLGRYEEAIEDYEKALELDP--------DDAEALYNLGLAYLRLGRYEEALADYEQAL 69

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 280 EREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV-VIQGKNQDA 338
Cdd:COG0457  70 ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAlLELGRYDEA 129
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
200-338 5.55e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 5.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 200 ELETSEKEALAReeraRGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVL 279
Cdd:COG0457   2 ELDPDDAEAYNN----LGLAYRRLGRYEEAIEDYEKALELDP--------DDAEALYNLGLAYLRLGRYEEALADYEQAL 69

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 280 EREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV-VIQGKNQDA 338
Cdd:COG0457  70 ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAlLELGRYDEA 129
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 187-348 8.57e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 8.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   187 LTLASFTQGRDSWELETSE-KEALAREERA-----RGTELFRAGNPEGAARCYGRALRLlltlpppgppERTVLHANLAA 260
Cdd:TIGR02917  96 LARAYLLQGKFQQVLDELPgKTLLDDEGAAellalRGLAYLGLGQLELAQKSYEQALAI----------DPRSLYAKLGL 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   261 CQLLLGQPQL--AAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDA 338
Cdd:TIGR02917 166 AQLALAENRFdeARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245

                         170
                  ....*....|..
gi 17149853   339 GL--AQGLRKMF 348
Cdd:TIGR02917 246 AEkhADALLKKA 257
TPR_1 pfam00515
Tetratricopeptide repeat;
287-319 1.13e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 44.33  E-value: 1.13e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 17149853   287 KALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 287-319 2.04e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 2.04e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 17149853    287 KALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 262-317 2.31e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.62  E-value: 2.31e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 17149853 262 QLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317
Cdd:cd24142  10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 223-327 1.73e-03

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 40.28  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853  223 AGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAAlGNL 302
Cdd:PRK09782 555 AGNGAARDRWLQQAEQRGL--------GDNALYWWLHAQRYIPGQPELALNDLTRSLNIAPSANAYVARATIYRQR-HNV 625

                         90       100
                 ....*....|....*....|....*
gi 17149853  303 EKATADLKKVLAIDPKNRAAQEELG 327
Cdd:PRK09782 626 PAAVSDLRAALELEPNNSNYQAALG 650
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
200-338 5.55e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 5.55e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 200 ELETSEKEALAReeraRGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVL 279
Cdd:COG0457   2 ELDPDDAEAYNN----LGLAYRRLGRYEEAIEDYEKALELDP--------DDAEALYNLGLAYLRLGRYEEALADYEQAL 69

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 280 EREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV-VIQGKNQDA 338
Cdd:COG0457  70 ELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAlLELGRYDEA 129
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 158-341 2.06e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.18  E-value: 2.06e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 158 ELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRAL 237
Cdd:COG3914  26 LALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRAL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 238 RLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317
Cdd:COG3914 106 ALNP--------DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDP 177

                       170       180
                ....*....|....*....|....
gi 17149853 318 KNRAAQEELGKVVIQGKNQDAGLA 341
Cdd:COG3914 178 DNAEALNNLGNALQDLGRLEEAIA 201
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
215-341 2.92e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.49  E-value: 2.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 215 ARGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGV 294
Cdd:COG0457  47 NLGLAYLRLGRYEEALADYEQALELDP--------DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGL 118

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 17149853 295 AQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLA 341
Cdd:COG0457 119 ALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 171-323 1.56e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 1.56e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 171 EEAELQLPGHSGPPVRLTLASFTQGRDSwELETSEKEALAREERA------RGTELFRAGNPEGAARCYGRALRLLLtlp 244
Cdd:COG3914  68 AAAAAALLLLAALLELAALLLQALGRYE-EALALYRRALALNPDNaealfnLGNLLLALGRLEEALAALRRALALNP--- 143

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17149853 245 ppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQ 323
Cdd:COG3914 144 -----DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 207-342 1.89e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 1.89e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 207 EALAREERARGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHL 286
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDP--------DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 17149853 287 KALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQ 342
Cdd:COG4783  73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 220-323 2.39e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 2.39e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 220 LFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAAL 299
Cdd:COG4235  27 YLRLGRYDEALAAYEKALRLDP--------DNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQ 98

                        90       100
                ....*....|....*....|....
gi 17149853 300 GNLEKATADLKKVLAIDPKNRAAQ 323
Cdd:COG4235  99 GDYAEAIAAWQKLLALLPADAPAR 122
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
216-322 2.61e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 62.63  E-value: 2.61e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 216 RGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVA 295
Cdd:COG4785  79 RGVAYDSLGDYDLAIADFDQALELDP--------DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                        90       100
                ....*....|....*....|....*..
gi 17149853 296 QAALGNLEKATADLKKVLAIDPKNRAA 322
Cdd:COG4785 151 LYYLGRYELAIADLEKALELDPNDPER 177
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 255-338 2.09e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 57.71  E-value: 2.09e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 255 HANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV-VIQG 333
Cdd:COG4235  20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAaFQQG 99


                ....*
gi 17149853 334 KNQDA 338
Cdd:COG4235 100 DYAEA 104
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 201-341 1.22e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 1.22e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 201 LETSEKEALAREERARGteLFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLE 280
Cdd:COG2956 103 LELDPDDAEALRLLAEI--YEQEGDWEKAIEVLERLLKLGP--------ENAHAYCELAELYLEQGDYDEAIEALEKALK 172

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17149853 281 REPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLA 341
Cdd:COG2956 173 LDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 205-317 1.26e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 1.26e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 205 EKEALAREERARGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPG 284
Cdd:COG5010  49 KLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDP--------NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD 120

                        90       100       110
                ....*....|....*....|....*....|...
gi 17149853 285 HLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317
Cdd:COG5010 121 NPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 208-342 1.85e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 1.85e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 208 ALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLK 287
Cdd:COG5010  10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE 89

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 17149853 288 ALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQ 342
Cdd:COG5010  90 LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
226-342 3.78e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.08  E-value: 3.78e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 226 PEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKA 305
Cdd:COG4785  47 ALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAA 126

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 17149853 306 TADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQ 342
Cdd:COG4785 127 LEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIAD 163
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 200-319 1.14e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 1.14e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 200 ELETSEKEALAreerARGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVL 279
Cdd:COG4783  32 ELDPDNPEAFA----LLGEILLQLGDLDEAIVLLHEALELDP--------DEPEARLNLGLALLKAGDYDEALALLEKAL 99

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 17149853 280 EREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:COG4783 100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
220-321 1.59e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.71  E-value: 1.59e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 220 LFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQlAAQSCDRVLEREPGHLKALYRRGVAQAAL 299
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDP--------DNADALNNLGLLLLEQGRYD-EAIALEKALKLDPNNAEALLNLAELLLEL 72

                        90       100
                ....*....|....*....|..
gi 17149853 300 GNLEKATADLKKVLAIDPKNRA 321
Cdd:COG3063  73 GDYDEALAYLERALELDPSALR 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
216-324 3.24e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.86  E-value: 3.24e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 216 RGTELFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVA 295
Cdd:COG0457  82 LGLALQALGRYEEALEDYDKALELDP--------DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        90       100
                ....*....|....*....|....*....
gi 17149853 296 QAALGNLEKATADLKKVLAIDPKNRAAQE 324
Cdd:COG0457 154 LEKLGRYEEALELLEKLEAAALAALLAAA 182
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 219-324 3.77e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 51.15  E-value: 3.77e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 219 ELFRAGNPEGAARCYGRALRLLLTLPPPGPPertvlHANLAACQLLLGQPQLAAQSCDRVLEREPGHLK---ALYRRGVA 295
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFLKRYPNSPLAPDA-----LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLS 76

                        90       100
                ....*....|....*....|....*....
gi 17149853 296 QAALGNLEKATADLKKVLAIDPKNRAAQE 324
Cdd:COG1729  77 YLELGDYDKARATLEELIKKYPDSEAAKE 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 201-347 5.18e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 5.18e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 201 LETSEKEALAREERARgtELFRAGNPEGAARCYGRALRLLLTLPPpgppertvLHANLAACQLLLGQPQLAAQSCDRVLE 280
Cdd:COG2956 137 LKLGPENAHAYCELAE--LYLEQGDYDEAIEALEKALKLDPDCAR--------ALLLLAELYLEQGDYEEAIAALERALE 206

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17149853 281 REPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNrAAQEELGKVVIQGKNQDAGLAQGLRKM 347
Cdd:COG2956 207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQL 272
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 187-348 8.57e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 8.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   187 LTLASFTQGRDSWELETSE-KEALAREERA-----RGTELFRAGNPEGAARCYGRALRLlltlpppgppERTVLHANLAA 260
Cdd:TIGR02917  96 LARAYLLQGKFQQVLDELPgKTLLDDEGAAellalRGLAYLGLGQLELAQKSYEQALAI----------DPRSLYAKLGL 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   261 CQLLLGQPQL--AAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDA 338
Cdd:TIGR02917 166 AQLALAENRFdeARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245

                         170
                  ....*....|..
gi 17149853   339 GL--AQGLRKMF 348
Cdd:TIGR02917 246 AEkhADALLKKA 257
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
261-338 1.03e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 1.03e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17149853 261 CQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKAtADLKKVLAIDPKNRAAQEELGKVVI-QGKNQDA 338
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLeLGDYDEA 78
TPR_1 pfam00515
Tetratricopeptide repeat;
287-319 1.13e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 44.33  E-value: 1.13e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 17149853   287 KALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 219-341 1.67e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 1.67e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 219 ELFRA-GNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQA 297
Cdd:COG2956  50 NLYRRrGEYDRAIRIHQKLLERDP--------DRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE 121

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 17149853 298 ALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLA 341
Cdd:COG2956 122 QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 254-342 1.88e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 1.88e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 254 LHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQG 333
Cdd:COG2956  44 AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQE 123


                ....*....
gi 17149853 334 KNQDAGLAQ 342
Cdd:COG2956 124 GDWEKAIEV 132
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 271-341 4.80e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 4.80e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17149853 271 AAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLA 341
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEE 72
TPR_19 pfam14559
Tetratricopeptide repeat;
266-329 1.75e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 42.19  E-value: 1.75e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17149853   266 GQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV 329
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 287-319 2.04e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.89  E-value: 2.04e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 17149853    287 KALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
279-338 2.54e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 2.54e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17149853 279 LEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV-VIQGKNQDA 338
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAyLRLGRYEEA 61
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 287-318 2.23e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.89  E-value: 2.23e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 17149853   287 KALYRRGVAQAALGNLEKATADLKKVLAIDPK 318
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 262-317 2.31e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.62  E-value: 2.31e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 17149853 262 QLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317
Cdd:cd24142  10 LLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDP 65
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 201-326 2.47e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.05  E-value: 2.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   201 LETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLltlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLE 280
Cdd:TIGR00990 118 LSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECK---------PDPVYYSNRAACHNALGDWEKVVEDTTAALE 188

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 17149853   281 REPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEEL 326
Cdd:TIGR00990 189 LDPDYSKALNRRANAYDGLGKYADALLDLTASCIIDGFRNEQSAQA 234
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 263-338 3.54e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.59  E-value: 3.54e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853 263 LLLGQPQLAAQSCDRVLEREPGHL---KALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQE---ELGKV-VIQGKN 335
Cdd:COG1729   4 LKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDallKLGLSyLELGDY 83


                ...
gi 17149853 336 QDA 338
Cdd:COG1729  84 DKA 86
TPR_9 pfam13371
Tetratricopeptide repeat;
266-322 1.13e-03

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 37.20  E-value: 1.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 17149853   266 GQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAA 322
Cdd:pfam13371   9 EDWERALAVVERLLLLAPDDPEERRDRGLLYAQLGCFQAALEDLEAYLELAPDAPDA 65
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 223-327 1.73e-03

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 40.28  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853  223 AGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAAlGNL 302
Cdd:PRK09782 555 AGNGAARDRWLQQAEQRGL--------GDNALYWWLHAQRYIPGQPELALNDLTRSLNIAPSANAYVARATIYRQR-HNV 625

                         90       100
                 ....*....|....*....|....*
gi 17149853  303 EKATADLKKVLAIDPKNRAAQEELG 327
Cdd:PRK09782 626 PAAVSDLRAALELEPNNSNYQAALG 650
TPR_8 pfam13181
Tetratricopeptide repeat;
286-318 2.88e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 2.88e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 17149853   286 LKALYRRGVAQAALGNLEKATADLKKVLAIDPK 318
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 220-292 5.01e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 38.82  E-value: 5.01e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17149853 220 LFRAGNPEGAARCYGRALRLLLtlpppgppERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRR 292
Cdd:COG3914 156 LRRLGRLEEAIAALRRALELDP--------DNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 265-319 5.31e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.00  E-value: 5.31e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 17149853   265 LGQPQLAAQSCDRVLERE---PGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319
Cdd:pfam13432  10 AGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 258-340 6.18e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.53  E-value: 6.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   258 LAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQD 337
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTE 686


                  ...
gi 17149853   338 AGL 340
Cdd:TIGR02917 687 SAK 689
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 258-327 7.17e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.53  E-value: 7.17e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   258 LAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELG 327
Cdd:TIGR02917 335 LASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG 404
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 216-339 8.17e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 8.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17149853   216 RGTELFRAGNPEGAARCYGRALRLLLTLPPPgppertvlHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVA 295
Cdd:TIGR02917 199 KGDLLLSLGNIELALAAYRKAIALRPNNIAV--------LLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALV 270

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 17149853   296 QAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQ-GKNQDAG 339
Cdd:TIGR02917 271 DFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQlGNLEQAY 315
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 277-342 9.14e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 9.14e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17149853   277 RVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQ 342
Cdd:TIGR02917 286 DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 255-318 9.47e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 9.47e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17149853   255 HANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPK 318
Cdd:TIGR02917 196 LLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPN 259
TPR_11 pfam13414
TPR repeat;
298-329 9.80e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 33.60  E-value: 9.80e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 17149853   298 ALGNLEKATADLKKVLAIDPKNRAAQEELGKV 329
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLA 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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