|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
3-339 |
6.30e-48 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 164.78 E-value: 6.30e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEKLRIEHQTITTPSKKKI 82
Cdd:PRK12402 4 LWTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADFFDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 83 EISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETssqrDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI 162
Cdd:PRK12402 84 YLVEDPRFAHFLGTDKRIRSSKIDNFKHVLKEYASYRPLSA----DYKTILLDNAEALREDAQQALRRIMEQYSRTCRFI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 163 LCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYPFTE 242
Cdd:PRK12402 160 IATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 243 dQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLthcippeiIMKGL-----LSELLHNCDGQLKG----EVAQ 313
Cdd:PRK12402 240 -EAAYEALGDVGTDEVIESLLDAAEAGDFTDARKTLDDLL--------IDEGLsggevLEELLRVARSRYRGdnlaRLHR 310
|
330 340
....*....|....*....|....*.
gi 124249204 314 MAAYYEHRLQLGSKAIYHLEAFVAKF 339
Cdd:PRK12402 311 LAADADARLTDGANDRIQLEALLAEL 336
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
19-342 |
8.88e-33 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 123.55 E-value: 8.88e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 19 HKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTRIMCILRELYGigveklrieHQTITTPSKKKIEISTIASNYH---LE 94
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLC---------ENPEGGKACGQCHSRLMAAGNHpdlLE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 95 VNPSDAGNSDRV-VIQEMLKTVAQsqqleTSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIP 173
Cdd:COG0470 72 LNPEEKSDQIGIdQIRELGEFLSL-----TPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 174 PIRSRCLAVRVPAPSIEDICSVLstvcRKEGLALPstLARRLAEKSCRNLRKALLMCEAcrvqqypftedqeipetdWEV 253
Cdd:COG0470 147 TIRSRCQVIRFRPPSEEEALAWL----REEGVDED--ALEAILRLAGGDPRAAINLLQA------------------LAG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 254 Y--LRETANAIVSQQTPQRLLEV--RGRLYELLthcippEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAI 329
Cdd:COG0470 203 RkeLLEDLAALLSRDRALELLDAllKAEALELL------DWLLKWLLDNLPLEYAGEDLARAYEALSEADRRLGRYANDR 276
|
330
....*....|...
gi 124249204 330 YHLEAFVAKFMAL 342
Cdd:COG0470 277 LLLEALLAKLGRL 289
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
21-179 |
6.91e-09 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 54.07 E-value: 6.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 21 EQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEklriehqtittpskkkieistiasnyHLEVNPSDA 100
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP--------------------------FLYLNASDL 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 101 GNSDRVVIQEMLKTVAQSQQLEtsSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMST------CRLILCCNSTS--KVI 172
Cdd:cd00009 59 LEGLVVAELFGHFLVRLLFELA--EKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPLlgDLD 136
|
....*..
gi 124249204 173 PPIRSRC 179
Cdd:cd00009 137 RALYDRL 143
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
18-188 |
1.05e-07 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 51.06 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 18 YHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTRIMCILRELYGigvEKLRIEHQTITTPSKKKIEiSTIASNYHLeVN 96
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFC---EEPGDDLPCGQCRSCRRIE-SGNHPDLVI-IE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 97 PSdaGNSDRV-VIQEMLKTVAQSqqletSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPI 175
Cdd:pfam13177 76 PE--GQSIKIdQIRELQKEFSKS-----PYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTI 148
|
170
....*....|...
gi 124249204 176 RSRCLAVRVPAPS 188
Cdd:pfam13177 149 RSRCQIIRFKPLS 161
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
37-190 |
6.19e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.44 E-value: 6.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 37 HLLVYGPSGAGKKTRIMCILREL--YGIGVEKLRIEHQTITTPSKKKIEISTIasnyhlevnpsDAGNSDRVVIQEMLKT 114
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELgpPGGGVIYIDGEDILEEVLDQLLLIIVGG-----------KKASGSGELRLRLALA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 115 VAQsqqletssQRDFKVVLLTEVDKLTKDAQHALRR--------TMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPA 186
Cdd:smart00382 73 LAR--------KLKPDVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVL 144
|
....
gi 124249204 187 PSIE 190
Cdd:smart00382 145 LLIL 148
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
3-164 |
1.81e-04 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 43.41 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-----LLVYGPSGAGKKTRIMCILRELyGIGVeklrIEHQTITTP 77
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL-GIQV----QEWSNPTLP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 78 SKKKIEISTIASnyhLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQRDFKVVLLTEVDK---LTKDAQHALRRTMEK 154
Cdd:TIGR00602 148 DFQKNDHKVTLS---LESCFSNFQSQIEVFSEFLLRATNKLQMLGDDLMTDKKIILVEDLPNqfyRDTRALHEILRWKYV 224
|
170
....*....|
gi 124249204 155 YMSTCRLILC 164
Cdd:TIGR00602 225 SIGRCPLVFI 234
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
3-339 |
6.30e-48 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 164.78 E-value: 6.30e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEKLRIEHQTITTPSKKKI 82
Cdd:PRK12402 4 LWTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADFFDQGKK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 83 EISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETssqrDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI 162
Cdd:PRK12402 84 YLVEDPRFAHFLGTDKRIRSSKIDNFKHVLKEYASYRPLSA----DYKTILLDNAEALREDAQQALRRIMEQYSRTCRFI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 163 LCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYPFTE 242
Cdd:PRK12402 160 IATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 243 dQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLthcippeiIMKGL-----LSELLHNCDGQLKG----EVAQ 313
Cdd:PRK12402 240 -EAAYEALGDVGTDEVIESLLDAAEAGDFTDARKTLDDLL--------IDEGLsggevLEELLRVARSRYRGdnlaRLHR 310
|
330 340
....*....|....*....|....*.
gi 124249204 314 MAAYYEHRLQLGSKAIYHLEAFVAKF 339
Cdd:PRK12402 311 LAADADARLTDGANDRIQLEALLAEL 336
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
3-345 |
7.98e-45 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 156.19 E-value: 7.98e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGigvEKLRiehqtittpskkki 82
Cdd:PRK00440 6 IWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYG---EDWR-------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 83 eistiasNYHLEVNPSDAGNSDrvVIQEMLKTVAQSQQLETSsqrDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI 162
Cdd:PRK00440 69 -------ENFLELNASDERGID--VIRNKIKEFARTAPVGGA---PFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFI 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 163 LCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALlmceacRVQQYPFTE 242
Cdd:PRK00440 137 LSCNYSSKIIDPIQSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAI------NALQAAAAT 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 243 DQEIPEtdwevylrETANAIVSQQTPQ------------RLLEVRGRLYELLT-HCIPPEIIMKGLLSELLH-NCDGQLK 308
Cdd:PRK00440 211 GKEVTE--------EAVYKITGTARPEeiremielalngDFTEAREKLRDLMIdYGLSGEDIIKQIHREVWSlDIPEELK 282
|
330 340 350
....*....|....*....|....*....|....*..
gi 124249204 309 GEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKK 345
Cdd:PRK00440 283 VELIDAIGEADFRITEGANERIQLEALLAKLALLGKK 319
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
4-205 |
4.17e-34 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 127.92 E-value: 4.17e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 4 WVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGigveklriehqtittPSKKkie 83
Cdd:PLN03025 3 WVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLG---------------PNYK--- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 84 istiasNYHLEVNPSDAGNSDrvVIQEMLKTVAQSQQleTSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLIL 163
Cdd:PLN03025 65 ------EAVLELNASDDRGID--VVRNKIKMFAQKKV--TLPPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFAL 134
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 124249204 164 CCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGL 205
Cdd:PLN03025 135 ACNTSSKIIEPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKV 176
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
19-342 |
8.88e-33 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 123.55 E-value: 8.88e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 19 HKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTRIMCILRELYGigveklrieHQTITTPSKKKIEISTIASNYH---LE 94
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLC---------ENPEGGKACGQCHSRLMAAGNHpdlLE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 95 VNPSDAGNSDRV-VIQEMLKTVAQsqqleTSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIP 173
Cdd:COG0470 72 LNPEEKSDQIGIdQIRELGEFLSL-----TPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 174 PIRSRCLAVRVPAPSIEDICSVLstvcRKEGLALPstLARRLAEKSCRNLRKALLMCEAcrvqqypftedqeipetdWEV 253
Cdd:COG0470 147 TIRSRCQVIRFRPPSEEEALAWL----REEGVDED--ALEAILRLAGGDPRAAINLLQA------------------LAG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 254 Y--LRETANAIVSQQTPQRLLEV--RGRLYELLthcippEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAI 329
Cdd:COG0470 203 RkeLLEDLAALLSRDRALELLDAllKAEALELL------DWLLKWLLDNLPLEYAGEDLARAYEALSEADRRLGRYANDR 276
|
330
....*....|...
gi 124249204 330 YHLEAFVAKFMAL 342
Cdd:COG0470 277 LLLEALLAKLGRL 289
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
93-339 |
9.08e-27 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 111.47 E-value: 9.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 93 LEVNPSDAGNSDrvVIQEMLKTVAQSQQLETSSqrdFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVI 172
Cdd:PRK04132 600 LELNASDERGIN--VIREKVKEFARTKPIGGAS---FKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKII 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 173 PPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALlmceacRVQQYPFTEDQEIpeTDWE 252
Cdd:PRK04132 675 EPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAI------NILQAAAALDDKI--TDEN 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 253 VYLretanaIVSQQTPQ------------RLLEVRGRLYE-LLTHCIPPEIIMKGLLSELLH-NCDGQLKGEVAQMAAYY 318
Cdd:PRK04132 747 VFL------VASRARPEdiremmllalkgNFLKAREKLREiLLKQGLSGEDVLVQMHREVFNlPIDEPKKVELADKIGEY 820
|
250 260
....*....|....*....|.
gi 124249204 319 EHRLQLGSKAIYHLEAFVAKF 339
Cdd:PRK04132 821 NFRLVEGANEMIQLEALLAQF 841
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
3-206 |
2.72e-18 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 84.27 E-value: 2.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPS-GAGKKTRIMCILRElygIGVEklriehqtittpskkk 81
Cdd:PHA02544 10 MWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSpGTGKTTVAKALCNE---VGAE---------------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 82 ieistiasnyHLEVNPSDaGNSDrvVIQEMLKTVAQSQQLETSsqrdFKVVLLTEVDKL-TKDAQHALRRTMEKYMSTCR 160
Cdd:PHA02544 71 ----------VLFVNGSD-CRID--FVRNRLTRFASTVSLTGG----GKVIIIDEFDRLgLADAQRHLRSFMEAYSKNCS 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 124249204 161 LILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLS-------TVCRKEGLA 206
Cdd:PHA02544 134 FIITANNKNGIIEPLRSRCRVIDFGVPTKEEQIEMMKqmivrckGILEAEGVE 186
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
10-342 |
2.25e-15 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 76.00 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 10 PSSLARLDYHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKT--RIM-----CilrelygigveklriEHQTITTP---- 77
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTlaRILakalnC---------------ENGPTGEPcgec 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 78 -SKKKIeistiASNYHLEVNPSDAGNSDRVV--IQEMLKTVAQSqqletSSQRDFKVVLLTEVDKLTKDAQHALRRTME- 153
Cdd:COG2812 71 eSCRAI-----AAGSHPDVIEIDAEASNIGVddIRELIEKVSYA-----PVEGRYKVYIIDEAHMLTTEAFNALLKTLEe 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 154 -----KymstcrLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALL 228
Cdd:COG2812 141 ppphvV------FILATTEPQKLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALS 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 229 MCeacrvqqypfteDQEIP--ETDWEVYLRETANAIVSQQTPQRLLEV-----RGR-----LYELLTHCIppEIIMKGLL 296
Cdd:COG2812 215 LL------------DQAIAfgLLDRRELLLDLLEALLAGDVAALLALAeelakRGRdlkrfLDDLLSLLR--DLLLLKLG 280
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 124249204 297 SELLHNCDGQLKGEVAQMAAYY-----EHRLQLGSKAIYHLEAFVAKFMAL 342
Cdd:COG2812 281 PDAELLVNEDERERLQELARRLsperlLRAIQILLEARRELERNVNPRLAL 331
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
7-273 |
6.18e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 63.25 E-value: 6.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVY-GPSGAGKKT--RIMcilrelygigVEKLRIEHQTITTPSKKKIE 83
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFaGPRGTGKTTvaRIL----------AKSLNCENRKGVEPCNECRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 84 ISTIASNYHLEVNPSDAGnSDRVV--IQEMLKTVAQsqqleTSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRL 161
Cdd:PRK14962 77 CRSIDEGTFMDVIELDAA-SNRGIdeIRKIRDAVGY-----RPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVF 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 162 ILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEacrvQQYPFT 241
Cdd:PRK14962 151 VLATTNLEKVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLE----QVWKFS 226
|
250 260 270
....*....|....*....|....*....|..
gi 124249204 242 EDQEIPETdwevyLRETAnAIVSQQTPQRLLE 273
Cdd:PRK14962 227 EGKITLET-----VHEAL-GLIPIEVVRDYIN 252
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
21-179 |
6.91e-09 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 54.07 E-value: 6.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 21 EQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVEklriehqtittpskkkieistiasnyHLEVNPSDA 100
Cdd:cd00009 5 EAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAP--------------------------FLYLNASDL 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 101 GNSDRVVIQEMLKTVAQSQQLEtsSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMST------CRLILCCNSTS--KVI 172
Cdd:cd00009 59 LEGLVVAELFGHFLVRLLFELA--EKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPLlgDLD 136
|
....*..
gi 124249204 173 PPIRSRC 179
Cdd:cd00009 137 RALYDRL 143
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
108-228 |
1.04e-08 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 56.07 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 108 IQEMLKTVAQSQQLETSSQrdFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAP 187
Cdd:PRK07940 99 VDEVRELVTIAARRPSTGR--WRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTP 176
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 124249204 188 SIEDICSVLStvcRKEGLAlPST-------------LARRLA-EKSCRNLRKALL 228
Cdd:PRK07940 177 SVEAVAEVLV---RRDGVD-PETarraarasqghigRARRLAtDEEARARRAEVL 227
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
7-231 |
1.63e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 55.59 E-value: 1.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHL-LVYGPSGAGKKTrimcILRELygigVEKLRIEHQTITTPSKKKIEIS 85
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTT----IARLL----AKSLNCQNGITSNPCRKCIICK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 86 TIASNYHLEVNPSDAGNSDRVviqEMLKTVAQSQQLETSSQRdFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCC 165
Cdd:PRK14961 81 EIEKGLCLDLIEIDAASRTKV---EEMREILDNIYYSPSKSR-FKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILAT 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124249204 166 NSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCE 231
Cdd:PRK14961 157 TDVEKIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLE 222
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
1-232 |
1.93e-08 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 55.70 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 1 MSLWVDKYRPSSLARLDYHKEQAAQLRNLVQcgDFPH------LLVYGPSGAGKKTRIMCILRELygiGVEKlriehqti 74
Cdd:PRK04195 1 MMPWVEKYRPKTLSDVVGNEKAKEQLREWIE--SWLKgkpkkaLLLYGPPGVGKTSLAHALANDY---GWEV-------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 75 ttpskkkieistiasnyhLEVNPSDAGNSDrvVIQEMLKTVAQSQQLeTSSQRdfKVVLLTEVD---------------K 139
Cdd:PRK04195 68 ------------------IELNASDQRTAD--VIERVAGEAATSGSL-FGARR--KLILLDEVDgihgnedrggarailE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 140 LTKDAQHAlrrtmekymstcrLILCCN---STSKviPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLA 216
Cdd:PRK04195 125 LIKKAKQP-------------IILTANdpyDPSL--RELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIA 189
|
250
....*....|....*.
gi 124249204 217 EKSCRNLRKALLMCEA 232
Cdd:PRK04195 190 ERSGGDLRSAINDLQA 205
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
7-319 |
4.39e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 54.71 E-value: 4.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTrimcILRelygIGVEKLRIEHQTITTPSKKKIEIS 85
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTT----IAR----ILAKSLNCENAQHGEPCGVCQSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 86 TIASNYHLEVNPSDAGNSDRVviqEMLKTVAQSQQLETSSQRdFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCC 165
Cdd:PRK08691 81 QIDAGRYVDLLEIDAASNTGI---DNIREVLENAQYAPTAGK-YKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILAT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 166 NSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKAL-LMCEACRVQQYPFTED- 243
Cdd:PRK08691 157 TDPHKVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALsLLDQAIALGSGKVAENd 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 244 --QEIPETDWEvYLRETANAIVSQQTPQRLLEVR-------------GRLYELLTH-----CIPPEIIMKGLLSELLHNC 303
Cdd:PRK08691 237 vrQMIGAVDKQ-YLYELLTGIINQDGAALLAKAQemaacavgfdnalGELAILLQQlaliqAVPSALAHDDPDSDILHRL 315
|
330
....*....|....*.
gi 124249204 304 DGQLKGEVAQMaaYYE 319
Cdd:PRK08691 316 AQTISGEQIQL--YYQ 329
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
18-188 |
1.05e-07 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 51.06 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 18 YHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTRIMCILRELYGigvEKLRIEHQTITTPSKKKIEiSTIASNYHLeVN 96
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFC---EEPGDDLPCGQCRSCRRIE-SGNHPDLVI-IE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 97 PSdaGNSDRV-VIQEMLKTVAQSqqletSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPI 175
Cdd:pfam13177 76 PE--GQSIKIdQIRELQKEFSKS-----PYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTI 148
|
170
....*....|...
gi 124249204 176 RSRCLAVRVPAPS 188
Cdd:pfam13177 149 RSRCQIIRFKPLS 161
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
7-231 |
1.44e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 52.87 E-value: 1.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKT--RI--MCilrelygigvekLRIEHQTITTPSKKK 81
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTcaRIisLC------------LNCSNGPTSDPCGTC 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 82 IEISTIASNYHLEVNPSDAGNSDRV----VIQEmlktvaQSQQLETSSQrdFKVVLLTEVDKLTKDAQHALRRTMEKYMS 157
Cdd:PRK14964 74 HNCISIKNSNHPDVIEIDAASNTSVddikVILE------NSCYLPISSK--FKVYIIDEVHMLSNSAFNALLKTLEEPAP 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124249204 158 TCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCE 231
Cdd:PRK14964 146 HVKFILATTEVKKIPVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLE 219
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
129-227 |
3.73e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 51.75 E-value: 3.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 129 FKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALP 208
Cdd:PRK14953 120 YKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYE 199
|
90
....*....|....*....
gi 124249204 209 STLARRLAEKSCRNLRKAL 227
Cdd:PRK14953 200 EKALDLLAQASEGGMRDAA 218
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
7-272 |
5.46e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 51.03 E-value: 5.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVY-GPSGAGKKTrimCIlrelygigveklRIEHQTITTPSkkkieIS 85
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFcGPRGVGKTT---CA------------RILARKINQPG-----YD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 86 TIASNYHLEVNPSDAGNSDRVV-IQEMLKTVAQSQQLEtssqrDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILC 164
Cdd:PRK14970 70 DPNEDFSFNIFELDAASNNSVDdIRNLIDQVRIPPQTG-----KYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 165 CNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEacRVQQY------ 238
Cdd:PRK14970 145 TTEKHKIIPTILSRCQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFD--RVVTFcgknit 222
|
250 260 270
....*....|....*....|....*....|....*.
gi 124249204 239 --PFTEDQEIpeTDWEVYLRETaNAIVSQQTPQRLL 272
Cdd:PRK14970 223 rqAVTENLNI--LDYDTYINVT-DLILENKIPELLL 255
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
7-227 |
7.47e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 50.85 E-value: 7.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVY-GPSGAGKKTrimcilreLYGIGVEKLRIEHQTITTPSKKKIEIS 85
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFtGTRGVGKTT--------LGRLLAKCLNCKTGVTAEPCNKCENCV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 86 TIASNYHLEVNPSDAgnSDRVVIQEMLKTVAQSQQLetSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCC 165
Cdd:PRK14957 81 AINNNSFIDLIEIDA--ASRTGVEETKEILDNIQYM--PSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILAT 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124249204 166 NSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKAL 227
Cdd:PRK14957 157 TDYHKIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDAL 218
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
7-227 |
2.43e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 49.28 E-value: 2.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVY-GPSGAGKKTrimcILRelygIGVEKLRIEHQTITTPSKKKIEIS 85
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFtGTRGVGKTT----IAR----ILAKCLNCETGVTSTPCEVCATCK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 86 TIASNYHLEVNPSDAGNSDRVV-IQEMLKTVAQSqqletSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILC 164
Cdd:PRK14960 80 AVNEGRFIDLIEIDAASRTKVEdTRELLDNVPYA-----PTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124249204 165 CNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKAL 227
Cdd:PRK14960 155 TTDPQKLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDAL 217
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
37-190 |
6.19e-06 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.44 E-value: 6.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 37 HLLVYGPSGAGKKTRIMCILREL--YGIGVEKLRIEHQTITTPSKKKIEISTIasnyhlevnpsDAGNSDRVVIQEMLKT 114
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELgpPGGGVIYIDGEDILEEVLDQLLLIIVGG-----------KKASGSGELRLRLALA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 115 VAQsqqletssQRDFKVVLLTEVDKLTKDAQHALRR--------TMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPA 186
Cdd:smart00382 73 LAR--------KLKPDVLILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVL 144
|
....
gi 124249204 187 PSIE 190
Cdd:smart00382 145 LLIL 148
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
19-197 |
1.22e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 46.56 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 19 HKEQAAQLRNLVQCGDFPHL-LVYGPSGAGK----KTRIMCILRElyGIGVEKLRIEHQTITtpSKKKIEISTIasnyhl 93
Cdd:PRK05564 9 HENIKNRIKNSIIKNRFSHAhIIVGEDGIGKsllaKEIALKILGK--SQQREYVDIIEFKPI--NKKSIGVDDI------ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 94 evnpsdagnsdRVVIQEMLKTVAQSqqletssqrDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIP 173
Cdd:PRK05564 79 -----------RNIIEEVNKKPYEG---------DKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILD 138
|
170 180
....*....|....*....|....
gi 124249204 174 PIRSRCLAVRVPAPSIEDICSVLS 197
Cdd:PRK05564 139 TIKSRCQIYKLNRLSKEEIEKFIS 162
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
7-205 |
1.60e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 46.48 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVY-GPSGAGKKTrimcILRelygIGVEKLRIEHQTITTPSKKK---I 82
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFfGPRGVGKTT----IAR----ILAKRLNCENPIGNEPCNECtscL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 83 EISTIASNYHLEVNPsdAGNSDRVVIQEMLKTVAQSqqletSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI 162
Cdd:PRK14956 83 EITKGISSDVLEIDA--ASNRGIENIRELRDNVKFA-----PMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFI 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 124249204 163 LCCNSTSKVIPPIRSRC---LAVRVPAPSIEDicsVLSTVCRKEGL 205
Cdd:PRK14956 156 LATTEFHKIPETILSRCqdfIFKKVPLSVLQD---YSEKLCKIENV 198
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
4-234 |
1.78e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 46.39 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 4 WVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTRIMCILRelyGIGVEKLRIEHQTITTPSKKKI 82
Cdd:PRK06645 11 FARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAK---AVNCSALITENTTIKTCEQCTN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 83 EIStIASNYHLEVNPSDAGNSDRVviqEMLKTVAQSQQLEtSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI 162
Cdd:PRK06645 88 CIS-FNNHNHPDIIEIDAASKTSV---DDIRRIIESAEYK-PLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFI 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124249204 163 LCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACR 234
Cdd:PRK06645 163 FATTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAA 234
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
22-191 |
3.70e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 45.08 E-value: 3.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 22 QAAQLRNLVQCGDFPH-LLVYGPSGAGKK---TRIMCIL-----RELYGIGveklriehqtittpSKKKIEISTIAS--- 89
Cdd:PRK05707 8 QQSLWQQLAGRGRHPHaYLLHGPAGIGKRalaERLAAALlceapQGGGACG--------------SCKGCQLLRAGShpd 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 90 NYHLEvnPSDAGNSDRV-VIQEMLKTVAQSQQletssQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNST 168
Cdd:PRK05707 74 NFVLE--PEEADKTIKVdQVRELVSFVVQTAQ-----LGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQP 146
|
170 180
....*....|....*....|...
gi 124249204 169 SKVIPPIRSRCLAVRVPAPSIED 191
Cdd:PRK05707 147 SRLLPTIKSRCQQQACPLPSNEE 169
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
7-272 |
5.75e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.77 E-value: 5.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 7 KYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-LLVYGPSGAGKKTrimCIlrelygigveklRIEHQTI--TTPSKKKIE 83
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTT---CA------------RIFAKTIncQNLTADGEA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 84 ISTIASNYHLEVNPS------DAGNSDRVV-IQEMLKTVAQSQQLETssqrdFKVVLLTEVDKLTKDAQHALRRTMEKYM 156
Cdd:PRK14971 75 CNECESCVAFNEQRSynihelDAASNNSVDdIRNLIEQVRIPPQIGK-----YKIYIIDEVHMLSQAAFNAFLKTLEEPP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 157 STCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGL-ALPSTLArRLAEKSCRNLRKALLMCEacrv 235
Cdd:PRK14971 150 SYAIFILATTEKHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGItAEPEALN-VIAQKADGGMRDALSIFD---- 224
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 124249204 236 QQYPFTED----QEIPET----DWEVYLRETaNAIVSQQTPQRLL 272
Cdd:PRK14971 225 QVVSFTGGnityKSVIENlnilDYDYYFRLT-DALLAGKVSDSLL 268
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
4-48 |
8.83e-05 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 44.44 E-value: 8.83e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 124249204 4 WVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGK 48
Cdd:PRK04132 9 WVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK 53
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
123-229 |
9.46e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 43.87 E-value: 9.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 123 TSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVcrk 202
Cdd:PRK09112 136 TSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHL--- 212
|
90 100
....*....|....*....|....*....
gi 124249204 203 eGLALPST--LARRLAEKSCRNLRKALLM 229
Cdd:PRK09112 213 -GSSQGSDgeITEALLQRSKGSVRKALLL 240
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
130-222 |
1.70e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 43.29 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 130 KVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGL-ALP 208
Cdd:PRK14963 118 KVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGReAEP 197
|
90
....*....|....*.
gi 124249204 209 STLA--RRLAEKSCRN 222
Cdd:PRK14963 198 EALQlvARLADGAMRD 213
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
3-164 |
1.81e-04 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 43.41 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-----LLVYGPSGAGKKTRIMCILRELyGIGVeklrIEHQTITTP 77
Cdd:TIGR00602 73 PWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL-GIQV----QEWSNPTLP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 78 SKKKIEISTIASnyhLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQRDFKVVLLTEVDK---LTKDAQHALRRTMEK 154
Cdd:TIGR00602 148 DFQKNDHKVTLS---LESCFSNFQSQIEVFSEFLLRATNKLQMLGDDLMTDKKIILVEDLPNqfyRDTRALHEILRWKYV 224
|
170
....*....|
gi 124249204 155 YMSTCRLILC 164
Cdd:TIGR00602 225 SIGRCPLVFI 234
|
|
| PRK07132 |
PRK07132 |
DNA polymerase III subunit delta'; Validated |
121-197 |
2.04e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180855 [Multi-domain] Cd Length: 299 Bit Score: 42.79 E-value: 2.04e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124249204 121 LETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSVLS 197
Cdd:PRK07132 83 FSSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKLL 159
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
87-226 |
2.56e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 42.84 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 87 IASNYHLEVNPSDaGNSDRVV--IQEMLKTVaqsqqLETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILC 164
Cdd:PRK06305 84 ISSGTSLDVLEID-GASHRGIedIRQINETV-----LFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLA 157
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124249204 165 CNSTSKVIPPIRSRC---LAVRVPAPSIEDicsVLSTVCRKEGLALPSTLARRLAEKSCRNLRKA 226
Cdd:PRK06305 158 TTEIHKIPGTILSRCqkmHLKRIPEETIID---KLALIAKQEGIETSREALLPIARAAQGSLRDA 219
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
3-169 |
2.99e-04 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 41.10 E-value: 2.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 3 LWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPH-----LLVYGPSGAGKKTRIMCILRELyGIGVEKlRIEHQTITTP 77
Cdd:pfam03215 8 QWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL-GPKYRE-WSNPTSFRSP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 78 SKKKieistiaSNYHLEVNPSDAGNSDRVVIQEMLKTVAQS---QQLETSSQRDFKVVLLTEVDKLTKDAQHALRRTMEK 154
Cdd:pfam03215 86 PNQV-------TDFRGDCIVNSRFLSQMESFSEFELKGARYlvmQKRGKNAQGNKKLILIEDLPNVFHIDTRRFQQVIRQ 158
|
170 180
....*....|....*....|.
gi 124249204 155 YMSTCR---LILC---CNSTS 169
Cdd:pfam03215 159 WLYSSEplpLIICiteCEILE 179
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
93-227 |
4.36e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 42.04 E-value: 4.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124249204 93 LEVnpsDAGNSDRVviQEMLKTVAQSQQLETSSQrdFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVI 172
Cdd:PRK14969 91 IEV---DAASNTQV--DAMRELLDNAQYAPTRGR--FKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIP 163
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 124249204 173 PPIRSRCLAVRVPAPSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKAL 227
Cdd:PRK14969 164 VTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDAL 218
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
187-252 |
2.12e-03 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 35.97 E-value: 2.12e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124249204 187 PSIEDICSVLSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQqypfteDQEIPETDWE 252
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAG------GGVITEEDVY 60
|
|
| |
