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Conserved domains on  [gi|226246638|ref|NP_081393|]
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kelch domain-containing protein 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
78-341 2.57e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 2.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  78 WKKInteGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSAdrglQWERIDcqGIPPSSKDKLGVWVYKNKL 157
Cdd:COG3055    3 WSSL---PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELA--PLPGPPRHHAAAVAQDGKL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 158 IFFGGYgylpedkvlgtfefdeTSFWNSSHPRgwnDHVHILDTETFAWSQpitTGKAPSPRAAHACATVGNKGFVFGGRY 237
Cdd:COG3055   74 YVFGGF----------------TGANPSSTPL---NDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWD 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 238 RDARMNDLHYLNLDTWEWNELIPqgvCPVGRSWHSLTPVSSDHLFLFGGFTT---------------------------- 289
Cdd:COG3055  132 DGGNVAWVEVYDPATGTWTQLAP---LPTPRDHLAAAVLPDGKILVIGGRNGsgfsntwttlaplptaraghaaavlggk 208

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 226246638 290 ------EKQPLSDAWTYCISKNEWIQFNHpyVEKPRLWHTACASDeGEVIVFGGCANN 341
Cdd:COG3055  209 ilvfggESGFSDEVEAYDPATNTWTALGE--LPTPRHGHAAVLTD-GKVYVIGGETKP 263
Kelch_4 pfam13418
Galactose oxidase, central domain;
32-89 1.12e-03

Galactose oxidase, central domain;


:

Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 226246638   32 RSGHVAVSDGRHM-FVWGGYKSNQVRgLYDfylpreeLWIYNMETGRWKKInteGDVPP 89
Cdd:pfam13418   2 RAYHTSTSIPDDTiYLFGGEGEDGTL-LSD-------LWVFDLSTNEWTRL---GSLPS 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
78-341 2.57e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 2.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  78 WKKInteGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSAdrglQWERIDcqGIPPSSKDKLGVWVYKNKL 157
Cdd:COG3055    3 WSSL---PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELA--PLPGPPRHHAAAVAQDGKL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 158 IFFGGYgylpedkvlgtfefdeTSFWNSSHPRgwnDHVHILDTETFAWSQpitTGKAPSPRAAHACATVGNKGFVFGGRY 237
Cdd:COG3055   74 YVFGGF----------------TGANPSSTPL---NDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWD 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 238 RDARMNDLHYLNLDTWEWNELIPqgvCPVGRSWHSLTPVSSDHLFLFGGFTT---------------------------- 289
Cdd:COG3055  132 DGGNVAWVEVYDPATGTWTQLAP---LPTPRDHLAAAVLPDGKILVIGGRNGsgfsntwttlaplptaraghaaavlggk 208

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 226246638 290 ------EKQPLSDAWTYCISKNEWIQFNHpyVEKPRLWHTACASDeGEVIVFGGCANN 341
Cdd:COG3055  209 ilvfggESGFSDEVEAYDPATNTWTALGE--LPTPRHGHAAVLTD-GKVYVIGGETKP 263
PLN02193 PLN02193
nitrile-specifier protein
 29-296 1.49e-12

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 68.83  E-value: 1.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  29 PAERSGHVAVSDGRHMFVWGG-YKSNQvrglydfylPREE-LWIYNMETGRWKKINTEGDVPP-SMSGSCAVCVDRVLYL 105
Cdd:PLN02193 163 PGLRCSHGIAQVGNKIYSFGGeFTPNQ---------PIDKhLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYV 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 106 FGGHHSRGNTNKFYMLDSRSAdrglQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNS 185
Cdd:PLN02193 234 FGGRDASRQYNGFYSFDTTTN----EWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKWFHC 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 186 SHP----------------------RGWN----DHVHILDTETFAWSQPITTGKAPSPRAAHACATVGNKGFVFGGryrD 239
Cdd:PLN02193 310 STPgdsfsirggaglevvqgkvwvvYGFNgcevDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG---E 386

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226246638 240 ARMNDLHY------------LNLDTWEWNELIPQGV---CPVGRSWHSLTPVSSD---HLFLFGGftteKQPLSD 296
Cdd:PLN02193 387 IAMDPLAHvgpgqltdgtfaLDTETLQWERLDKFGEeeeTPSSRGWTASTTGTIDgkkGLVMHGG----KAPTND 457
Kelch_4 pfam13418
Galactose oxidase, central domain;
267-307 2.72e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 46.84  E-value: 2.72e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 226246638  267 GRSWHSLTPVSSDHLFLFGGFTTEKQPLSDAWTYCISKNEW 307
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEW 41
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 48-157 2.20e-04

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 42.35  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638   48 GGYKsnqVRGLYDFYLPR--EELWIYNMETGRWKKIntEGDVPPSMSGSCAVCVDRVLYLFGghhSRGNTNKFYML---D 122
Cdd:TIGR01640  53 KQYK---VLCFSDRSGNRnqSEHQVYTLGSNSWRTI--ECSPPHHPLKSRGVCINGVLYYLA---YTLKTNPDYFIvsfD 124

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 226246638  123 SRSadrglqwER----IDCQGIPPSSKDKLGVWVYKNKL 157
Cdd:TIGR01640 125 VSS-------ERfkefIPLPCGNSDSVDYLSLINYKGKL 156
Kelch_4 pfam13418
Galactose oxidase, central domain;
32-89 1.12e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 226246638   32 RSGHVAVSDGRHM-FVWGGYKSNQVRgLYDfylpreeLWIYNMETGRWKKInteGDVPP 89
Cdd:pfam13418   2 RAYHTSTSIPDDTiYLFGGEGEDGTL-LSD-------LWVFDLSTNEWTRL---GSLPS 49
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
78-341 2.57e-19

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 87.13  E-value: 2.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  78 WKKInteGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSAdrglQWERIDcqGIPPSSKDKLGVWVYKNKL 157
Cdd:COG3055    3 WSSL---PDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATN----TWSELA--PLPGPPRHHAAAVAQDGKL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 158 IFFGGYgylpedkvlgtfefdeTSFWNSSHPRgwnDHVHILDTETFAWSQpitTGKAPSPRAAHACATVGNKGFVFGGRY 237
Cdd:COG3055   74 YVFGGF----------------TGANPSSTPL---NDVYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWD 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 238 RDARMNDLHYLNLDTWEWNELIPqgvCPVGRSWHSLTPVSSDHLFLFGGFTT---------------------------- 289
Cdd:COG3055  132 DGGNVAWVEVYDPATGTWTQLAP---LPTPRDHLAAAVLPDGKILVIGGRNGsgfsntwttlaplptaraghaaavlggk 208

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 226246638 290 ------EKQPLSDAWTYCISKNEWIQFNHpyVEKPRLWHTACASDeGEVIVFGGCANN 341
Cdd:COG3055  209 ilvfggESGFSDEVEAYDPATNTWTALGE--LPTPRHGHAAVLTD-GKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
204-357 1.42e-15

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 76.35  E-value: 1.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 204 AWSqpiTTGKAPSPRAAHACATVGNKGFVFGGRYRDARMNDLHYLNLDTWEWNELIPqgvCPVGRSWHSLTPVSSDHLFL 283
Cdd:COG3055    2 TWS---SLPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAP---LPGPPRHHAAAVAQDGKLYV 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 226246638 284 FGGFTTEK---QPLSDAWTYCISKNEWIQfnHPYVEKPRLWHTAcASDEGEVIVFGGcannllvHHRAAHSNEVLIF 357
Cdd:COG3055   76 FGGFTGANpssTPLNDVYVYDPATNTWTK--LAPMPTPRGGATA-LLLDGKIYVVGG-------WDDGGNVAWVEVY 142
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
30-298 3.11e-13

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 69.41  E-value: 3.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  30 AERSGHVAVSDGRHMFVWGGYksnqvRGLYDFYLPREELWIYNMETGRWKKInteGDVPPSMSGSCAVCVDRVLYLFGGH 109
Cdd:COG3055   59 PPRHHAAAVAQDGKLYVFGGF-----TGANPSSTPLNDVYVYDPATNTWTKL---APMPTPRGGATALLLDGKIYVVGGW 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 110 HSRGNTNKFYMLDsrsaDRGLQWERIdcqGIPPSSKDKL-GVWVYKNKLIFFGGYgylpedkvlgtfefDETSFWNsshp 188
Cdd:COG3055  131 DDGGNVAWVEVYD----PATGTWTQL---APLPTPRDHLaAAVLPDGKILVIGGR--------------NGSGFSN---- 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 189 rgwndhvhildtetfAWSqpiTTGKAPSPRAAHACATVGNKGFVFGGRYrdARMNDLHYLNLDTWEWNELipqGVCPVGR 268
Cdd:COG3055  186 ---------------TWT---TLAPLPTARAGHAAAVLGGKILVFGGES--GFSDEVEAYDPATNTWTAL---GELPTPR 242

                        250       260       270
                 ....*....|....*....|....*....|.
gi 226246638 269 swHSLTPVS-SDHLFLFGGFTTEKQPLSDAW 298
Cdd:COG3055  243 --HGHAAVLtDGKVYVIGGETKPGVRTPLVT 271
PLN02193 PLN02193
nitrile-specifier protein
 29-296 1.49e-12

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 68.83  E-value: 1.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  29 PAERSGHVAVSDGRHMFVWGG-YKSNQvrglydfylPREE-LWIYNMETGRWKKINTEGDVPP-SMSGSCAVCVDRVLYL 105
Cdd:PLN02193 163 PGLRCSHGIAQVGNKIYSFGGeFTPNQ---------PIDKhLYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYV 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 106 FGGHHSRGNTNKFYMLDSRSAdrglQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNS 185
Cdd:PLN02193 234 FGGRDASRQYNGFYSFDTTTN----EWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKWFHC 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 186 SHP----------------------RGWN----DHVHILDTETFAWSQPITTGKAPSPRAAHACATVGNKGFVFGGryrD 239
Cdd:PLN02193 310 STPgdsfsirggaglevvqgkvwvvYGFNgcevDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG---E 386

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226246638 240 ARMNDLHY------------LNLDTWEWNELIPQGV---CPVGRSWHSLTPVSSD---HLFLFGGftteKQPLSD 296
Cdd:PLN02193 387 IAMDPLAHvgpgqltdgtfaLDTETLQWERLDKFGEeeeTPSSRGWTASTTGTIDgkkGLVMHGG----KAPTND 457
PLN02153 PLN02153
epithiospecifier protein
 212-337 1.41e-10

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 62.31  E-value: 1.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 212 GKAPSPRAAHACATVGNKGFVFGGRYRDARM--NDLHYLNLDTWEWNELIPQGVCPVGRSWHSLTPVSSDHLFLFGGfTT 289
Cdd:PLN02153  17 GKGPGPRCSHGIAVVGDKLYSFGGELKPNEHidKDLYVFDFNTHTWSIAPANGDVPRISCLGVRMVAVGTKLYIFGG-RD 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 226246638 290 EKQPLSDAWTYCISKNEWIQFNHPYVE---KPRLWHTAcASDEGEVIVFGG 337
Cdd:PLN02153  96 EKREFSDFYSYDTVKNEWTFLTKLDEEggpEARTFHSM-ASDENHVYVFGG 145
PLN02153 PLN02153
epithiospecifier protein
 29-303 1.92e-10

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 61.93  E-value: 1.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  29 PAERSGHVAVSDGRHMFVWGG-YKSNQVRGlydfylprEELWIYNMETGRWKKINTEGDVPP-SMSGSCAVCVDRVLYLF 106
Cdd:PLN02153  20 PGPRCSHGIAVVGDKLYSFGGeLKPNEHID--------KDLYVFDFNTHTWSIAPANGDVPRiSCLGVRMVAVGTKLYIF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 107 GGHHSRGNTNKFYMLDSRSAdrglQWE---RIDCQGIPPS------SKDKLGVWVY----KNKL--------------IF 159
Cdd:PLN02153  92 GGRDEKREFSDFYSYDTVKN----EWTfltKLDEEGGPEArtfhsmASDENHVYVFggvsKGGLmktperfrtieaynIA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 160 FGGYGYLP------EDKVLGTFEFDETSFW------NSSHPRGWNDH----VHILDTETFAWSQPITTGKAPSPRAAHAC 223
Cdd:PLN02153 168 DGKWVQLPdpgenfEKRGGAGFAVVQGKIWvvygfaTSILPGGKSDYesnaVQFFDPASGKWTEVETTGAKPSARSVFAH 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 224 ATVGNKGFVFGGR-YRDAR--------MNDLHYLNLDTWEWNELIPQGVCPVGRSWHSLTPVSSD---HLFLFGGFTTEK 291
Cdd:PLN02153 248 AVVGKYIIIFGGEvWPDLKghlgpgtlSNEGYALDTETLVWEKLGECGEPAMPRGWTAYTTATVYgknGLLMHGGKLPTN 327

                        330
                 ....*....|..
gi 226246638 292 QPLSDAWTYCIS 303
Cdd:PLN02153 328 ERTDDLYFYAVN 339
PLN02193 PLN02193
nitrile-specifier protein
 131-313 3.85e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.51  E-value: 3.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 131 QWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYgYLPEDKVlgtfefdetsfwnsshprgwNDHVHILDTETFAWSQPIT 210
Cdd:PLN02193 152 KWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGE-FTPNQPI--------------------DKHLYVFDLETRTWSISPA 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 211 TGKAPSPRAAHAC-ATVGNKGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGVCPVGRSWHSLTpVSSDHLFLFGGFT- 288
Cdd:PLN02193 211 TGDVPHLSCLGVRmVSIGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMA-ADEENVYVFGGVSa 289

                        170       180
                 ....*....|....*....|....*
gi 226246638 289 TEKQPLSDAwtYCISKNEWIQFNHP 313
Cdd:PLN02193 290 TARLKTLDS--YNIVDKKWFHCSTP 312
PLN02193 PLN02193
nitrile-specifier protein
 205-337 6.70e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 54.19  E-value: 6.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 205 WSQPITTGKAPSPRAAHACATVGNKGFVFGGRYRDARMND--LHYLNLDTWEWNELIPQGVCPvGRSWHSLTPVS-SDHL 281
Cdd:PLN02193 153 WIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDkhLYVFDLETRTWSISPATGDVP-HLSCLGVRMVSiGSTL 231

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 226246638 282 FLFGGFTTEKQpLSDAWTYCISKNEWiQFNHPYVE--KPRLWHTAcASDEGEVIVFGG 337
Cdd:PLN02193 232 YVFGGRDASRQ-YNGFYSFDTTTNEW-KLLTPVEEgpTPRSFHSM-AADEENVYVFGG 286
Kelch_4 pfam13418
Galactose oxidase, central domain;
267-307 2.72e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 46.84  E-value: 2.72e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 226246638  267 GRSWHSLTPVSSDHLFLFGGFTTEKQPLSDAWTYCISKNEW 307
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEW 41
PLN02153 PLN02153
epithiospecifier protein
 25-247 1.81e-05

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 46.52  E-value: 1.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  25 ELACPAERSGHVAVSDGRHMFVWGGYKSNqvrGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGS-CAVCVDRVL 103
Cdd:PLN02153 121 EEGGPEARTFHSMASDENHVYVFGGVSKG---GLMKTPERFRTIEAYNIADGKWVQLPDPGENFEKRGGAgFAVVQGKIW 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638 104 YLFG-------GHHSRGNTNKFYMLDSRSAdrglQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGtfe 176
Cdd:PLN02153 198 VVYGfatsilpGGKSDYESNAVQFFDPASG----KWTEVETTGAKPSARSVFAHAVVGKYIIIFGGEVWPDLKGHLG--- 270

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 226246638 177 fdetsfwnsshPRGWNDHVHILDTETFAWSQPITTGKAPSPRA--AHACATV-GNKGFVF-GGRY-RDARMNDLHY 247
Cdd:PLN02153 271 -----------PGTLSNEGYALDTETLVWEKLGECGEPAMPRGwtAYTTATVyGKNGLLMhGGKLpTNERTDDLYF 335
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 217-258 9.54e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.52  E-value: 9.54e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 226246638  217 PRAAHACATVGNKGFVFGGRYRDARMNDLHYLNLDTWEWNEL 258
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKL 42
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 48-157 2.20e-04

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 42.35  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638   48 GGYKsnqVRGLYDFYLPR--EELWIYNMETGRWKKIntEGDVPPSMSGSCAVCVDRVLYLFGghhSRGNTNKFYML---D 122
Cdd:TIGR01640  53 KQYK---VLCFSDRSGNRnqSEHQVYTLGSNSWRTI--ECSPPHHPLKSRGVCINGVLYYLA---YTLKTNPDYFIvsfD 124

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 226246638  123 SRSadrglqwER----IDCQGIPPSSKDKLGVWVYKNKL 157
Cdd:TIGR01640 125 VSS-------ERfkefIPLPCGNSDSVDYLSLINYKGKL 156
Kelch_3 pfam13415
Galactose oxidase, central domain;
279-326 3.13e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 38.04  E-value: 3.13e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 226246638  279 DHLFLFGGFTTEKQP-LSDAWTYCISKNEWIQfnHPYVEKPRLWHTACA 326
Cdd:pfam13415   2 DKLYIFGGLGFDGQTrLNDLYVYDLDTNTWTQ--IGDLPPPRSGHSATY 48
PHA03098 PHA03098
kelch-like protein; Provisional
 57-187 8.04e-04

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 41.68  E-value: 8.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226246638  57 GLYDFYLPREELWIYNMETGRWKKINTegdVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSAdRGLQWERID 136
Cdd:PHA03098 397 GISKNDELLKTVECFSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGISYIDNIKVYNIVESYNP-VTNKWTELS 472

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 226246638 137 CQGIPpssKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEfDETSFWNSSH 187
Cdd:PHA03098 473 SLNFP---RINASLCIFNNKIYVVGGDKYEYYINEIEVYD-DKTNTWTLFC 519
Kelch_4 pfam13418
Galactose oxidase, central domain;
32-89 1.12e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 226246638   32 RSGHVAVSDGRHM-FVWGGYKSNQVRgLYDfylpreeLWIYNMETGRWKKInteGDVPP 89
Cdd:pfam13418   2 RAYHTSTSIPDDTiYLFGGEGEDGTL-LSD-------LWVFDLSTNEWTRL---GSLPS 49
Kelch_3 pfam13415
Galactose oxidase, central domain;
227-274 2.52e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 35.73  E-value: 2.52e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 226246638  227 GNKGFVFGGRYRDA--RMNDLHYLNLDTWEWNELipqGVCPVGRSWHSLT 274
Cdd:pfam13415   1 GDKLYIFGGLGFDGqtRLNDLYVYDLDTNTWTQI---GDLPPPRSGHSAT 47
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 29-76 4.43e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 34.85  E-value: 4.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 226246638   29 PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFylpreelWIYNMETG 76
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDV-------YVLSLPTF 41
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 88-122 7.41e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 34.08  E-value: 7.41e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 226246638   88 PPSMSGSCAVCVDRVLYLFGGHHSRGN--TNKFYMLD 122
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGqpSDDVYVLS 37
Kelch_6 pfam13964
Kelch motif;
217-258 9.67e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 34.23  E-value: 9.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 226246638  217 PRAAHACATVGNKGFVFGGRYRDA-RMNDLHYLNLDTWEWNEL 258
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASpALNKLEVYNPLTKSWEEL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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