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Conserved domains on  [gi|58037177|ref|NP_081483|]
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protein FAM174C precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1180 super family cl05954
Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian ...
 18-108 1.86e-09

Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown.


The actual alignment was detected with superfamily member pfam06679:

Pssm-ID: 429067  Cd Length: 167  Bit Score: 51.81  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037177    18 GSAENSSLPGPPYNHTNGRLPDrdtgsAVLRLFYVITGLCGLISLYFLIRAFRLKKSQR--RRYGLLTNTEEHEEMA--S 93
Cdd:pfam06679  74 GSAGGGSLAVSPEISSPLDKPM-----TLQRALTVLVVVSAAVIVYFVVRTVRMRRRNRktRRYGVLDTNIENMELTplE 148

                          90
                  ....*....|....*...
gi 58037177    94 QDSEEE---TVFETRNLR 108
Cdd:pfam06679 149 QDEDEDddnTLFDANHPR 166
 
Name Accession Description Interval E-value
DUF1180 pfam06679
Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian ...
 18-108 1.86e-09

Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown.


Pssm-ID: 429067  Cd Length: 167  Bit Score: 51.81  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037177    18 GSAENSSLPGPPYNHTNGRLPDrdtgsAVLRLFYVITGLCGLISLYFLIRAFRLKKSQR--RRYGLLTNTEEHEEMA--S 93
Cdd:pfam06679  74 GSAGGGSLAVSPEISSPLDKPM-----TLQRALTVLVVVSAAVIVYFVVRTVRMRRRNRktRRYGVLDTNIENMELTplE 148

                          90
                  ....*....|....*...
gi 58037177    94 QDSEEE---TVFETRNLR 108
Cdd:pfam06679 149 QDEDEDddnTLFDANHPR 166
YuzA COG2155
Uncharacterized membrane protein YuzA, DUF378 family [Function unknown];
42-74 9.93e-05

Uncharacterized membrane protein YuzA, DUF378 family [Function unknown];


Pssm-ID: 441758  Cd Length: 70  Bit Score: 37.51  E-value: 9.93e-05
                        10        20        30
                ....*....|....*....|....*....|...
gi 58037177  42 TGSAVLRLFYVITGLCGLISLYFLIRAFRLKKS 74
Cdd:COG2155  37 QASALSRIIYILVGLAGLYSLSLLFRIRKKPER 69
 
Name Accession Description Interval E-value
DUF1180 pfam06679
Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian ...
 18-108 1.86e-09

Protein of unknown function (DUF1180); This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown.


Pssm-ID: 429067  Cd Length: 167  Bit Score: 51.81  E-value: 1.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037177    18 GSAENSSLPGPPYNHTNGRLPDrdtgsAVLRLFYVITGLCGLISLYFLIRAFRLKKSQR--RRYGLLTNTEEHEEMA--S 93
Cdd:pfam06679  74 GSAGGGSLAVSPEISSPLDKPM-----TLQRALTVLVVVSAAVIVYFVVRTVRMRRRNRktRRYGVLDTNIENMELTplE 148

                          90
                  ....*....|....*...
gi 58037177    94 QDSEEE---TVFETRNLR 108
Cdd:pfam06679 149 QDEDEDddnTLFDANHPR 166
YuzA COG2155
Uncharacterized membrane protein YuzA, DUF378 family [Function unknown];
42-74 9.93e-05

Uncharacterized membrane protein YuzA, DUF378 family [Function unknown];


Pssm-ID: 441758  Cd Length: 70  Bit Score: 37.51  E-value: 9.93e-05
                        10        20        30
                ....*....|....*....|....*....|...
gi 58037177  42 TGSAVLRLFYVITGLCGLISLYFLIRAFRLKKS 74
Cdd:COG2155  37 QASALSRIIYILVGLAGLYSLSLLFRIRKKPER 69
DUF378 pfam04070
Domain of unknown function (DUF378); Predicted transmembrane domain of unknown function. The ...
 41-65 9.69e-03

Domain of unknown function (DUF378); Predicted transmembrane domain of unknown function. The majority of the family have two predicted transmembrane regions.


Pssm-ID: 461157  Cd Length: 60  Bit Score: 32.04  E-value: 9.69e-03
                          10        20
                  ....*....|....*....|....*
gi 58037177    41 DTGSAVLRLFYVITGLCGLISLYFL 65
Cdd:pfam04070  35 GQGSWLSRIIYALVGLAGLYCISLL 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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