NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|170932558|ref|NP_082315|]
View 

N-acetyltransferase ESCO2 [Mus musculus]

Protein Classification

ECO family N-acetyltransferase( domain architecture ID 10620681)

ECO family N-acetyltransferase contains a C2H2 zinc finger, is required for the establishment of sister chromatid cohesion, and may acetylate components of the cohesin complex

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
520-588 1.32e-36

ESCO1/2 acetyl-transferase;


:

Pssm-ID: 464015  Cd Length: 69  Bit Score: 130.68  E-value: 1.32e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170932558  520 EPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKYCNTPNFLVY 588
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGTDDFLVY 69
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
371-410 1.88e-16

zinc-finger of acetyl-transferase ESCO;


:

Pssm-ID: 464013  Cd Length: 40  Bit Score: 73.04  E-value: 1.88e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 170932558  371 QLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHR 410
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
520-588 1.32e-36

ESCO1/2 acetyl-transferase;


Pssm-ID: 464015  Cd Length: 69  Bit Score: 130.68  E-value: 1.32e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170932558  520 EPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKYCNTPNFLVY 588
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGTDDFLVY 69
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
371-410 1.88e-16

zinc-finger of acetyl-transferase ESCO;


Pssm-ID: 464013  Cd Length: 40  Bit Score: 73.04  E-value: 1.88e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 170932558  371 QLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHR 410
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
520-588 1.32e-36

ESCO1/2 acetyl-transferase;


Pssm-ID: 464015  Cd Length: 69  Bit Score: 130.68  E-value: 1.32e-36
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 170932558  520 EPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKYCNTPNFLVY 588
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGTDDFLVY 69
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
371-410 1.88e-16

zinc-finger of acetyl-transferase ESCO;


Pssm-ID: 464013  Cd Length: 40  Bit Score: 73.04  E-value: 1.88e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 170932558  371 QLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHR 410
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH