|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
291-635 |
2.72e-49 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 180.11 E-value: 2.72e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 291 LTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQ 370
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSAD-GTVRLWDLATGKLLRTLT 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 371 GHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNF 450
Cdd:COG2319 160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 451 RTFTSPRPtQFSCVAVDSSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDM 530
Cdd:COG2319 240 RTLTGHSG-SVRSVAFSPDGRLLASGSADG-TVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 531 fDSWRTKETLT-LTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGrhdlktgrkeldkitakHSAkgkAFT 609
Cdd:COG2319 318 -ATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTG-----------------HTG---AVT 376
|
330 340
....*....|....*....|....*.
gi 30102930 610 TLCYSADGQSILAGGMSKFVCLYHVR 635
Cdd:COG2319 377 SVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
322-629 |
2.77e-46 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 167.51 E-value: 2.77e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 322 LIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGD-GTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 402 TLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSprPTQF-SCVAVDSSGEIVSAGAQDS 480
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRG--HTDWvNSVAFSPDGTFVASSSQDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 481 FeIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMfDSWRTKETLTLTSDAL-AVTFRPDGAELA 559
Cdd:cd00200 158 T-IKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL-STGKCLGTLRGHENGVnSVAFSPDGYLLA 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 560 VATLNSQITFWDPENAVQVGSIEGrHDlktgrkeldkitakhsakgKAFTTLCYSADGQSILAGGMSKFV 629
Cdd:cd00200 236 SGSEDGTIRVWDLRTGECVQTLSG-HT-------------------NSVTSLAWSPDGKRLASGSADGTI 285
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
61-444 |
1.08e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 119.63 E-value: 1.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 61 VGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHF-HFKGSVHSVSFSPDGRKFVVT-KGNIAQMYHAPGKKREfnafvldK 138
Cdd:COG2319 84 VAFSPDGRLLASASADGTVRLWDLATGLLLRTLtGHTGAVRSVAFSPDGKTLASGsADGTVRLWDLATGKLL-------R 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 139 TYFGPYDETTCIDWTDDSKCFVVGSKDMSTWVFGAERWDNLiyYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCD 218
Cdd:COG2319 157 TLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLL--RTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 219 TPPEGLRLKAPRGWkadilqrekeeeeedeeegdrettirgkttpaeqervgkvkysrlakyflnkegdfnnLTSAAYHK 298
Cdd:COG2319 235 TGKLLRTLTGHSGS----------------------------------------------------------VRSVAFSP 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 299 KTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQGHFNSMVA 378
Cdd:COG2319 257 DGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDD-GTVRLWDLATGKLLRTLTGHTGAVRS 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30102930 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDL 444
Cdd:COG2319 336 VAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| Utp12 |
pfam04003 |
Dip2/Utp12 Family; This domain is found at the C-terminus of proteins containing WD40 repeats. ... |
770-875 |
1.41e-24 |
|
Dip2/Utp12 Family; This domain is found at the C-terminus of proteins containing WD40 repeats. These proteins are part of the U3 ribonucleoprotein the yeast protein is called Utp12 or DIP2.
Pssm-ID: 461125 Cd Length: 106 Bit Score: 98.78 E-value: 1.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 770 NEKKLAQEALEAVPQNEIEVVSTSLPELYVVKVLEFLAASF-EESRHLEFYLIWTQKLLMSHGQRLKSRAgQLLPVVQFL 848
Cdd:pfam04003 1 NDEYLLESVLEKIPPSDIELTLLRLPFSYVLRLLKFLAERLaERSPHLELLLRWLKFLLRTHGGYLVSNP-DLRPVLRSL 79
|
90 100
....*....|....*....|....*..
gi 30102930 849 QKGLQRHLDDVSKLCDWNRFNIQYVLA 875
Cdd:pfam04003 80 QKLLRRRLKELKDLLGLNLGALDYLLS 106
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
490-529 |
2.45e-10 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 56.17 E-value: 2.45e-10
10 20 30 40
....*....|....*....|....*....|....*....|
gi 30102930 490 TGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
20-401 |
8.47e-10 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 60.81 E-value: 8.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 20 LNFTHDGNSVISPVGNR-VTVFDLKNNR-SNTLPLATKyNIKCVGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHFH-FK 96
Cdd:cd00200 15 VAFSPDGKLLATGSGDGtIKVWDLETGElLRTLKGHTG-PVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTgHT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 97 GSVHSVSFSPDGRkFVVTKG--NIAQMYhapgkkrEFNAFVLDKTYFGPYDETTCIDWTDDSKcFVVGSKDMST---WVF 171
Cdd:cd00200 94 SYVSSVAFSPDGR-ILSSSSrdKTIKVW-------DVETGKCLTTLRGHTDWVNSVAFSPDGT-FVASSSQDGTiklWDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 172 GAERwdnlIYYALSGHKDAIvacffesnsldlyslsqdgalcvwqcdtppeglrlkaprgwkadilqrekeeeeedeeeg 251
Cdd:cd00200 165 RTGK----CVATLTGHTGEV------------------------------------------------------------ 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 252 drettirgkttpaeqervgkvkysrlakyflnkegdfnnlTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQ 331
Cdd:cd00200 181 ----------------------------------------NSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN 220
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 332 RVASVAINSSGDWIAfGCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:cd00200 221 GVNSVAFSPDGYLLA-SGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
491-529 |
4.03e-09 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 52.73 E-value: 4.03e-09
10 20 30
....*....|....*....|....*....|....*....
gi 30102930 491 GRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
497-591 |
2.77e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 497 LSGHEGPVSGLCFNP-MKSILASASWDKTVRLWDMfDSWRTKETLTLTSD-ALAVTFRPDGAELAVATLNSQITFWDPEN 574
Cdd:PTZ00421 121 LQGHTKKVGIVSFHPsAMNVLASAGADMVVNVWDV-ERGKAVEVIKCHSDqITSLEWNLDGSLLCTTSKDKKLNIIDPRD 199
|
90
....*....|....*..
gi 30102930 575 AVQVGSIEGRHDLKTGR 591
Cdd:PTZ00421 200 GTIVSSVEAHASAKSQR 216
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
291-635 |
2.72e-49 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 180.11 E-value: 2.72e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 291 LTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQ 370
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSAD-GTVRLWDLATGKLLRTLT 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 371 GHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNF 450
Cdd:COG2319 160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLL 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 451 RTFTSPRPtQFSCVAVDSSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDM 530
Cdd:COG2319 240 RTLTGHSG-SVRSVAFSPDGRLLASGSADG-TVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDL 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 531 fDSWRTKETLT-LTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGrhdlktgrkeldkitakHSAkgkAFT 609
Cdd:COG2319 318 -ATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTG-----------------HTG---AVT 376
|
330 340
....*....|....*....|....*.
gi 30102930 610 TLCYSADGQSILAGGMSKFVCLYHVR 635
Cdd:COG2319 377 SVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
322-644 |
1.50e-48 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 177.80 E-value: 1.50e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 322 LIHSLSISDQRVASVAINSSGDWIAFGcSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:COG2319 70 LLATLLGHTAAVLSVAFSPDGRLLASA-SADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWD 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 402 TLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSPRPTqFSCVAVDSSGEIVSAGAQDSf 481
Cdd:COG2319 149 LATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGA-VRSVAFSPDGKLLASGSADG- 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 482 EIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMfDSWRTKETLTLTSDA-LAVTFRPDGAELAV 560
Cdd:COG2319 227 TVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL-ATGELLRTLTGHSGGvNSVAFSPDGKLLAS 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 561 ATLNSQITFWDPENAVQVGSIEGRHDlktgrkeldkitakhsakgkAFTTLCYSADGQSILAGGMSKFVCLYHVREQILV 640
Cdd:COG2319 306 GSDDGTVRLWDLATGKLLRTLTGHTG--------------------AVRSVAFSPDGKTLASGSDDGTVRLWDLATGELL 365
|
....
gi 30102930 641 KRFE 644
Cdd:COG2319 366 RTLT 369
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
285-574 |
1.25e-46 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 172.40 E-value: 1.25e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 285 EGDFNNLTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSES 364
Cdd:COG2319 117 TGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDD-GTVRLWDLATGK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 365 YVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDL 444
Cdd:COG2319 196 LLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDL 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 445 HRYRNFRTFTSPRPTQFScVAVDSSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKT 524
Cdd:COG2319 276 ATGELLRTLTGHSGGVNS-VAFSPDGKLLASGSDDG-TVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGT 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 30102930 525 VRLWDMFDSWRTKETLTLTSDALAVTFRPDGAELAVATLNSQITFWDPEN 574
Cdd:COG2319 354 VRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
322-629 |
2.77e-46 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 167.51 E-value: 2.77e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 322 LIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGD-GTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 402 TLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSprPTQF-SCVAVDSSGEIVSAGAQDS 480
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRG--HTDWvNSVAFSPDGTFVASSSQDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 481 FeIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMfDSWRTKETLTLTSDAL-AVTFRPDGAELA 559
Cdd:cd00200 158 T-IKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDL-STGKCLGTLRGHENGVnSVAFSPDGYLLA 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 560 VATLNSQITFWDPENAVQVGSIEGrHDlktgrkeldkitakhsakgKAFTTLCYSADGQSILAGGMSKFV 629
Cdd:cd00200 236 SGSEDGTIRVWDLRTGECVQTLSG-HT-------------------NSVTSLAWSPDGKRLASGSADGTI 285
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
64-530 |
2.48e-38 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 148.14 E-value: 2.48e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 64 SPDGRLAIIVDEGGAALLVSLVCRSVLHHFHFKGSVHSVSFSPDGRKFV-VTKGNIAQMYHAPGKKREFnafvldkTYFG 142
Cdd:COG2319 46 PDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLAsASADGTVRLWDLATGLLLR-------TLTG 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 143 PYDETTCIDWTDDSKCFVVGSKDMSTWVFGAERWDNLiyYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCDTPPE 222
Cdd:COG2319 119 HTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLL--RTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 223 GLRLKAPRGWkadilqrekeeeeedeeegdrettirgkttpaeqervgkvkysrlakyflnkegdfnnLTSAAYHKKTHL 302
Cdd:COG2319 197 LRTLTGHTGA----------------------------------------------------------VRSVAFSPDGKL 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 303 LVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Cdd:COG2319 219 LASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSAD-GTVRLWDLATGELLRTLTGHSGGVNSVAFS 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRafdlhryrnfrtftsprptqfs 462
Cdd:COG2319 298 PDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVR---------------------- 355
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30102930 463 cvavdssgeivsagaqdsfeifVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDM 530
Cdd:COG2319 356 ----------------------LWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
302-529 |
2.95e-36 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 138.62 E-value: 2.95e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 302 LLVTGFASGIFhLHELPEFNLIHSLSISDQRVASVAINSSGDWIAfGCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAY 381
Cdd:cd00200 66 LASGSSDKTIR-LWDLETGECVRTLTGHTSYVSSVAFSPDGRILS-SSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAF 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 382 SPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDLHRYRNFRTFTSpRPTQF 461
Cdd:cd00200 144 SPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRG-HENGV 222
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30102930 462 SCVAVDSSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:cd00200 223 NSVAFSPDGYLLASGSEDG-TIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
350-644 |
1.81e-34 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 136.58 E-value: 1.81e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 350 SGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHV 429
Cdd:COG2319 13 SADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 430 IVTSSLDGTVRAFDLHRYRNFRTFTsPRPTQFSCVAVDSSGEIVSAGAQDSfEIFVWSMQTGRLLDVLSGHEGPVSGLCF 509
Cdd:COG2319 93 LASASADGTVRLWDLATGLLLRTLT-GHTGAVRSVAFSPDGKTLASGSADG-TVRLWDLATGKLLRTLTGHSGAVTSVAF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 510 NPMKSILASASWDKTVRLWDmFDSWRTKETLTLTSDAL-AVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDlk 588
Cdd:COG2319 171 SPDGKLLASGSDDGTVRLWD-LATGKLLRTLTGHTGAVrSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSG-- 247
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 30102930 589 tgrkeldkitakhsakgkAFTTLCYSADGQSILAGGMSKFVCLYHVREQILVKRFE 644
Cdd:COG2319 248 ------------------SVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLT 285
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
370-726 |
1.36e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 130.92 E-value: 1.36e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 370 QGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRafdlhryrn 449
Cdd:cd00200 6 KGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIR--------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 450 frtftsprptqfscvavdssgeivsagaqdsfeifVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:cd00200 77 -----------------------------------LWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWD 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 530 MFDswrTKETLTL---TSDALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGrHDlktgrkeldkitakhsakgK 606
Cdd:cd00200 122 VET---GKCLTTLrghTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTG-HT-------------------G 178
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 607 AFTTLCYSADGQSILAGGMSKFVCLYHVREQILVKrfelscnlSLDAMEEFLNRRKMTEFGNLALidqdAGEENGVAVpL 686
Cdd:cd00200 179 EVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLG--------TLRGHENGVNSVAFSPDGYLLA----SGSEDGTIR-V 245
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 30102930 687 PGVRKGDMSSRHFKPEIRVTSLRFSPTGRCWAATSTEGLL 726
Cdd:cd00200 246 WDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
61-444 |
1.08e-28 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 119.63 E-value: 1.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 61 VGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHF-HFKGSVHSVSFSPDGRKFVVT-KGNIAQMYHAPGKKREfnafvldK 138
Cdd:COG2319 84 VAFSPDGRLLASASADGTVRLWDLATGLLLRTLtGHTGAVRSVAFSPDGKTLASGsADGTVRLWDLATGKLL-------R 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 139 TYFGPYDETTCIDWTDDSKCFVVGSKDMSTWVFGAERWDNLiyYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCD 218
Cdd:COG2319 157 TLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLL--RTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 219 TPPEGLRLKAPRGWkadilqrekeeeeedeeegdrettirgkttpaeqervgkvkysrlakyflnkegdfnnLTSAAYHK 298
Cdd:COG2319 235 TGKLLRTLTGHSGS----------------------------------------------------------VRSVAFSP 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 299 KTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRVASVAINSSGDWIAFGCSGmGQLLVWEWQSESYVLKQQGHFNSMVA 378
Cdd:COG2319 257 DGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDD-GTVRLWDLATGKLLRTLTGHTGAVRS 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30102930 379 LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTLTEHSSGVTGVTFTTTGHVIVTSSLDGTVRAFDL 444
Cdd:COG2319 336 VAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| Utp12 |
pfam04003 |
Dip2/Utp12 Family; This domain is found at the C-terminus of proteins containing WD40 repeats. ... |
770-875 |
1.41e-24 |
|
Dip2/Utp12 Family; This domain is found at the C-terminus of proteins containing WD40 repeats. These proteins are part of the U3 ribonucleoprotein the yeast protein is called Utp12 or DIP2.
Pssm-ID: 461125 Cd Length: 106 Bit Score: 98.78 E-value: 1.41e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 770 NEKKLAQEALEAVPQNEIEVVSTSLPELYVVKVLEFLAASF-EESRHLEFYLIWTQKLLMSHGQRLKSRAgQLLPVVQFL 848
Cdd:pfam04003 1 NDEYLLESVLEKIPPSDIELTLLRLPFSYVLRLLKFLAERLaERSPHLELLLRWLKFLLRTHGGYLVSNP-DLRPVLRSL 79
|
90 100
....*....|....*....|....*..
gi 30102930 849 QKGLQRHLDDVSKLCDWNRFNIQYVLA 875
Cdd:pfam04003 80 QKLLRRRLKELKDLLGLNLGALDYLLS 106
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
20-232 |
1.49e-11 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 67.24 E-value: 1.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 20 LNFTHDGNSVIS-PVGNRVTVFDLKNNRSNTLPLATKYNIKCVGLSPDGRLAIIVDEGGAALLVSL---VCRSVLHHFHf 95
Cdd:COG2319 168 VAFSPDGKLLASgSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLatgKLLRTLTGHS- 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 96 kGSVHSVSFSPDGRKFVVT-KGNIAQMYHAPGKKrefnafvLDKTYFGPYDETTCIDWTDDSKCFVVGSKDMSTWVFGAE 174
Cdd:COG2319 247 -GSVRSVAFSPDGRLLASGsADGTVRLWDLATGE-------LLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLA 318
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 30102930 175 RWDNLiyYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCDTPPEGLRLKAPRGW 232
Cdd:COG2319 319 TGKLL--RTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGA 374
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
22-219 |
1.75e-11 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 67.24 E-value: 1.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 22 FTHDGNSVIS-PVGNRVTVFDLKNNRSNTLPLATKYNIKCVGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHF-HFKGSV 99
Cdd:COG2319 212 FSPDGKLLASgSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLtGHSGGV 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 100 HSVSFSPDGRKFVVT-KGNIAQMYHAPGKKrefnafvLDKTYFGPYDETTCIDWTDDSKCFVVGSKDMSTWVFGAErwDN 178
Cdd:COG2319 292 NSVAFSPDGKLLASGsDDGTVRLWDLATGK-------LLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLA--TG 362
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 30102930 179 LIYYALSGHKDAIVACFFESNSLDLYSLSQDGALCVWQCDT 219
Cdd:COG2319 363 ELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
490-529 |
2.45e-10 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 56.17 E-value: 2.45e-10
10 20 30 40
....*....|....*....|....*....|....*....|
gi 30102930 490 TGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
20-401 |
8.47e-10 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 60.81 E-value: 8.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 20 LNFTHDGNSVISPVGNR-VTVFDLKNNR-SNTLPLATKyNIKCVGLSPDGRLAIIVDEGGAALLVSLVCRSVLHHFH-FK 96
Cdd:cd00200 15 VAFSPDGKLLATGSGDGtIKVWDLETGElLRTLKGHTG-PVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTgHT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 97 GSVHSVSFSPDGRkFVVTKG--NIAQMYhapgkkrEFNAFVLDKTYFGPYDETTCIDWTDDSKcFVVGSKDMST---WVF 171
Cdd:cd00200 94 SYVSSVAFSPDGR-ILSSSSrdKTIKVW-------DVETGKCLTTLRGHTDWVNSVAFSPDGT-FVASSSQDGTiklWDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 172 GAERwdnlIYYALSGHKDAIvacffesnsldlyslsqdgalcvwqcdtppeglrlkaprgwkadilqrekeeeeedeeeg 251
Cdd:cd00200 165 RTGK----CVATLTGHTGEV------------------------------------------------------------ 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 252 drettirgkttpaeqervgkvkysrlakyflnkegdfnnlTSAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQ 331
Cdd:cd00200 181 ----------------------------------------NSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHEN 220
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 332 RVASVAINSSGDWIAfGCSGMGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:cd00200 221 GVNSVAFSPDGYLLA-SGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
491-529 |
4.03e-09 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 52.73 E-value: 4.03e-09
10 20 30
....*....|....*....|....*....|....*....
gi 30102930 491 GRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWD 529
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
466-644 |
2.17e-07 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 54.15 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 466 VDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPVSGLCFNPMKSILASASWDKTVRLWDMFDSWRTKETLTLTSD 545
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 546 ALAVTFRPDGAELAVATLNSQITFWDPENAVQVGSIEGRHDlktgrkeldkitakhsakgkAFTTLCYSADGQSILAGGM 625
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTG--------------------AVRSVAFSPDGKTLASGSA 140
|
170
....*....|....*....
gi 30102930 626 SKFVCLYHVREQILVKRFE 644
Cdd:COG2319 141 DGTVRLWDLATGKLLRTLT 159
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
362-401 |
1.20e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.77 E-value: 1.20e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 30102930 362 SESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
428-578 |
1.22e-06 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 50.85 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 428 HVIVTSSLDGTVRAFDLHRYRNFRTFTS-PRPTQfscVAVDSSGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPvSG 506
Cdd:COG3391 81 RLYVANSGSGRVSVIDLATGKVVATIPVgGGPRG---LAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGP-HG 156
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30102930 507 LCFNPMKSILASASWD-----KTVRLWDMfDSWRTKETLTLTSDALAVTFRPDGAELAVATLNSQITFWDpENAVQV 578
Cdd:COG3391 157 IAVDPDGKRLYVANSGsntvsVIVSVIDT-ATGKVVATIPVGGGPVGVAVSPDGRRLYVANRGSNTSNGG-SNTVSV 231
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
370-401 |
1.86e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 45.41 E-value: 1.86e-06
10 20 30
....*....|....*....|....*....|..
gi 30102930 370 QGHFNSMVALAYSPDGQYIVTGGDDGKVKVWN 401
Cdd:pfam00400 8 EGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
24-114 |
1.67e-05 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 47.38 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 24 HDGNS--VISPVGNRVTVFDLKNNR-SNTLPLATkyNIKCVGLSPDGRLAIIVDEGGAALLV-SLVCRSVLHHFHFKGSV 99
Cdd:COG3391 77 ADGRRlyVANSGSGRVSVIDLATGKvVATIPVGG--GPRGLAVDPDGGRLYVADSGNGRVSViDTATGKVVATIPVGAGP 154
|
90
....*....|....*
gi 30102930 100 HSVSFSPDGRKFVVT 114
Cdd:COG3391 155 HGIAVDPDGKRLYVA 169
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
22-114 |
8.29e-04 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.99 E-value: 8.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 22 FTHDGNS--VISPVGNRVTVFDLKNNRSnTLPLATKYNIKCVGLSPDGRLAIIVDEGGAAL--LVSLVC---RSVLHHFH 94
Cdd:COG3391 117 VDPDGGRlyVADSGNGRVSVIDTATGKV-VATIPVGAGPHGIAVDPDGKRLYVANSGSNTVsvIVSVIDtatGKVVATIP 195
|
90 100
....*....|....*....|
gi 30102930 95 FKGSVHSVSFSPDGRKFVVT 114
Cdd:COG3391 196 VGGGPVGVAVSPDGRRLYVA 215
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
497-591 |
2.77e-03 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.42 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30102930 497 LSGHEGPVSGLCFNP-MKSILASASWDKTVRLWDMfDSWRTKETLTLTSD-ALAVTFRPDGAELAVATLNSQITFWDPEN 574
Cdd:PTZ00421 121 LQGHTKKVGIVSFHPsAMNVLASAGADMVVNVWDV-ERGKAVEVIKCHSDqITSLEWNLDGSLLCTTSKDKKLNIIDPRD 199
|
90
....*....|....*..
gi 30102930 575 AVQVGSIEGRHDLKTGR 591
Cdd:PTZ00421 200 GTIVSSVEAHASAKSQR 216
|
|
| |
