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Conserved domains on  [gi|29789245|ref|NP_084032|]
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serologically defined colon cancer antigen 8 homolog isoform 1 [Mus musculus]

Protein Classification

CCCAP domain-containing protein( domain architecture ID 12175623)

CCCAP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CCCAP pfam15964
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
 6-710 0e+00

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.


:

Pssm-ID: 435040 [Multi-domain]  Cd Length: 703  Bit Score: 886.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245     6 GNSTLEDSLGQYQRSLRERANRSIHQLKCALREVDVTVEEDALDPSTSINVENEDTGVAWHELQHSHAVNQLKALLRQQT 85
Cdd:pfam15964   1 GNSTLEESLGQYQRSLRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    86 NKENETSPpRRRKLSPSRPSECDDGSMPTMHNLVPIINDQSQYIHHLEAEVKFCKDELSGMKNRVQVVVLENERLQQELK 165
Cdd:pfam15964  81 KKENELSP-RRRKLSPSRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   166 SQRPEETLREQTFLDASGNMQNSWiMTREDSRVDEAAKRPFSHGDAETGKTASTGDANKWKLELERLKLTYEAKTDLLES 245
Cdd:pfam15964 160 SQTQEETLREQTLLDSSGNMQNSW-CTPEDSRVHQTSKRPASHNLAERLKSATTGEDEKWRLELEKLKLLYEAKTEVLES 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   246 QLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSRVGGLCLKCAQHEAVLSQTHSNVHIQTIERLTKERDDLMSVLVS 325
Cdd:pfam15964 239 QVKSLRKDLAESQKTCEDLKERLKHKESLVAASTSSRVGGLCLKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALVS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   326 VRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMIKKEVARER 405
Cdd:pfam15964 319 VRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKER 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   406 EDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAK 485
Cdd:pfam15964 399 EELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTK 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   486 SHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQ 565
Cdd:pfam15964 479 TGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALQAQ 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   566 QREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKR 645
Cdd:pfam15964 559 QREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKR 638

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29789245   646 NDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQLP 710
Cdd:pfam15964 639 NEELEEQCVQHGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQVP 703
 
Name Accession Description Interval E-value
CCCAP pfam15964
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
 6-710 0e+00

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.


Pssm-ID: 435040 [Multi-domain]  Cd Length: 703  Bit Score: 886.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245     6 GNSTLEDSLGQYQRSLRERANRSIHQLKCALREVDVTVEEDALDPSTSINVENEDTGVAWHELQHSHAVNQLKALLRQQT 85
Cdd:pfam15964   1 GNSTLEESLGQYQRSLRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    86 NKENETSPpRRRKLSPSRPSECDDGSMPTMHNLVPIINDQSQYIHHLEAEVKFCKDELSGMKNRVQVVVLENERLQQELK 165
Cdd:pfam15964  81 KKENELSP-RRRKLSPSRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   166 SQRPEETLREQTFLDASGNMQNSWiMTREDSRVDEAAKRPFSHGDAETGKTASTGDANKWKLELERLKLTYEAKTDLLES 245
Cdd:pfam15964 160 SQTQEETLREQTLLDSSGNMQNSW-CTPEDSRVHQTSKRPASHNLAERLKSATTGEDEKWRLELEKLKLLYEAKTEVLES 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   246 QLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSRVGGLCLKCAQHEAVLSQTHSNVHIQTIERLTKERDDLMSVLVS 325
Cdd:pfam15964 239 QVKSLRKDLAESQKTCEDLKERLKHKESLVAASTSSRVGGLCLKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALVS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   326 VRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMIKKEVARER 405
Cdd:pfam15964 319 VRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKER 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   406 EDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAK 485
Cdd:pfam15964 399 EELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTK 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   486 SHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQ 565
Cdd:pfam15964 479 TGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALQAQ 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   566 QREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKR 645
Cdd:pfam15964 559 QREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKR 638

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29789245   646 NDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQLP 710
Cdd:pfam15964 639 NEELEEQCVQHGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQVP 703
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 401-709 9.40e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 9.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    401 VAREREDAESKMLILSQNIAKLEAQVEKVT---REKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEK 477
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEekiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    478 EHREYKAK----SHKDLEMKVQ------EIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKD 547
Cdd:TIGR02168  741 EVEQLEERiaqlSKELTELEAEieeleeRLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    548 SiQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEqyllLTSQNTFLTKLKEEccllAKKLEKVSLKSRSQIVR 627
Cdd:TIGR02168  821 N-LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESE----LEALLNERASLEEALAL 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    628 LSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQL--------LNKQNQLLLERQNLS 699
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEAR 971

                          330
                   ....*....|
gi 29789245    700 EEVARLRAQL 709
Cdd:TIGR02168  972 RRLKRLENKI 981
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 364-631 3.54e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 3.54e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 364 QCEQLKSELERQTERLEKELASQQEKRAvEKEMIKKEVAREREDAESK---MLILSQNIAKLEAQVEKVTREKTAAVSHL 440
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEA-ELEELRLELEELELELEEAqaeEYELLAELARLEQDIARLEERRRELEERL 318

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 441 EEIQNHVASQEMDVTkvcgEMRFQLNKTKMEKDEVEKEHREyKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAAR 520
Cdd:COG1196 319 EELEEELAELEEELE----ELEEELEELEEELEEAEEELEE-AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 521 ARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFL 600
Cdd:COG1196 394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                       250       260       270
                ....*....|....*....|....*....|.
gi 29789245 601 TKLKEECCLLAKKLEKVSLKSRSQIVRLSQE 631
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEADYE 504
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
237-539 7.60e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 7.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  237 EAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAAsassrvgGLCLKCAQheavlsQTHSNVHIQTIERLTKER 316
Cdd:PRK02224 411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEA-------GKCPECGQ------PVEGSPHVETIEEDRERV 477

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  317 DDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEAnfEKTKALIQ-CEQLKSELERQTERLE--KELASQQEKRAVE 393
Cdd:PRK02224 478 EELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLE--ERREDLEElIAERRETIEEKRERAEelRERAAELEAEAEE 555

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  394 KEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTRektaAVSHLEEIQNhvasqemdvtkvCGEMRFQLNKTKMEKD 473
Cdd:PRK02224 556 KREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER----IRTLLAAIAD------------AEDEIERLREKREALA 619

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 29789245  474 EVEKEHREY---KAKSHKDLEMKVQE--IEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQL 539
Cdd:PRK02224 620 ELNDERRERlaeKRERKRELEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL 690
 
Name Accession Description Interval E-value
CCCAP pfam15964
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
 6-710 0e+00

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.


Pssm-ID: 435040 [Multi-domain]  Cd Length: 703  Bit Score: 886.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245     6 GNSTLEDSLGQYQRSLRERANRSIHQLKCALREVDVTVEEDALDPSTSINVENEDTGVAWHELQHSHAVNQLKALLRQQT 85
Cdd:pfam15964   1 GNSTLEESLGQYQRSLRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    86 NKENETSPpRRRKLSPSRPSECDDGSMPTMHNLVPIINDQSQYIHHLEAEVKFCKDELSGMKNRVQVVVLENERLQQELK 165
Cdd:pfam15964  81 KKENELSP-RRRKLSPSRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   166 SQRPEETLREQTFLDASGNMQNSWiMTREDSRVDEAAKRPFSHGDAETGKTASTGDANKWKLELERLKLTYEAKTDLLES 245
Cdd:pfam15964 160 SQTQEETLREQTLLDSSGNMQNSW-CTPEDSRVHQTSKRPASHNLAERLKSATTGEDEKWRLELEKLKLLYEAKTEVLES 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   246 QLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSRVGGLCLKCAQHEAVLSQTHSNVHIQTIERLTKERDDLMSVLVS 325
Cdd:pfam15964 239 QVKSLRKDLAESQKTCEDLKERLKHKESLVAASTSSRVGGLCLKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALVS 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   326 VRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMIKKEVARER 405
Cdd:pfam15964 319 VRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKER 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   406 EDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAK 485
Cdd:pfam15964 399 EELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTK 478

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   486 SHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQ 565
Cdd:pfam15964 479 TGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLEKESIQQSFSNEAKAQALQAQ 558

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   566 QREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKR 645
Cdd:pfam15964 559 QREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKR 638

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29789245   646 NDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQLP 710
Cdd:pfam15964 639 NEELEEQCVQHGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQNQLFKERQNLTEEVQSLRSQVP 703
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 401-709 9.40e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 9.40e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    401 VAREREDAESKMLILSQNIAKLEAQVEKVT---REKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEK 477
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEekiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    478 EHREYKAK----SHKDLEMKVQ------EIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKD 547
Cdd:TIGR02168  741 EVEQLEERiaqlSKELTELEAEieeleeRLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    548 SiQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEqyllLTSQNTFLTKLKEEccllAKKLEKVSLKSRSQIVR 627
Cdd:TIGR02168  821 N-LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESE----LEALLNERASLEEALAL 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    628 LSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQL--------LNKQNQLLLERQNLS 699
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEAR 971

                          330
                   ....*....|
gi 29789245    700 EEVARLRAQL 709
Cdd:TIGR02168  972 RRLKRLENKI 981
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 306-652 1.69e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 1.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    306 IQTIERLTKERDDLMsvlvsvRSSLAEAQKRETSAYEQVkHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELAS 385
Cdd:TIGR02169  197 RQQLERLRREREKAE------RYQALLKEKREYEGYELL-KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    386 QQEKRAVEKEMIKKEvareredAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMdvtkvcgemrfQL 465
Cdd:TIGR02169  270 IEQLLEELNKKIKDL-------GEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA-----------EI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    466 NKTKMEKDEVEKEHREYKakshKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQEclrvtelLGEAERQLHLTRLE 545
Cdd:TIGR02169  332 DKLLAEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE-------LKDYREKLEKLKRE 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    546 KDSIQQSFSNEAKAQALQAQQREqELTQKIQQMETQHDKTESEqyllLTSQNTFLTKLKEECCLLAKKLEKVslksRSQI 625
Cdd:TIGR02169  401 INELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEE----KEDKALEIKKQEWKLEQLAADLSKY----EQEL 471

                          330       340
                   ....*....|....*....|....*..
gi 29789245    626 VRLSQEKRYLCDKLEKLQKRNDELEEQ 652
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQ 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 312-673 5.93e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.22  E-value: 5.93e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    312 LTKERDDLMSVLVSVRSSLAEAQKRetsayeqvkhaVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELAsQQEKRA 391
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEK-----------IEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQI 728

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    392 VEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTkvcgEMRFQLNKTKME 471
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREA 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    472 KDEVEKEHREYKAKSHK---DLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDS 548
Cdd:TIGR02168  805 LDELRAELTLLNEEAANlreRLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    549 IQQsfsneakaQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRL 628
Cdd:TIGR02168  885 LEE--------ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEA 956

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 29789245    629 SQEKRYLCDKLEKLQKRNDELEEQCIQHGRVH-------ETMKERLRQLDKH 673
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKRLENKIKELGPVNlaaieeyEELKERYDFLTAQ 1008
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 351-709 4.99e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 4.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    351 TEEANFEKTKALIQCEQLKSELERqTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVT 430
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIER-LDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    431 REKTAAVSHLEEIQnhvaSQEMDVTKVCGEMRFQLNK-TKMEKDEVEKEHREYKAKSHkdlEMKVqEIEKLRLELSESEQ 509
Cdd:TIGR02169  244 RQLASLEEELEKLT----EEISELEKRLEEIEQLLEElNKKIKDLGEEEQLRVKEKIG---ELEA-EIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    510 HVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNeakaqalqAQQREQELTQKIQQMETQHDKTESEq 589
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE--------LKEELEDLRAELEEVDKEFAETRDE- 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    590 yllLTSQNTFLTKLKEECCLLAKKLEKVSLKSRsqivRLSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQ 669
Cdd:TIGR02169  387 ---LKDYREKLEKLKREINELKRELDRLQEELQ----RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 29789245    670 LDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQL 709
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-712 1.22e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.98  E-value: 1.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    415 LSQNIAKLEAQVEKVTR-----------EKTAAVSHLEEIQNHVASQEMDVTkvcgEMRFQLNKTKMEKDEVEKEHREYK 483
Cdd:TIGR02168  198 LERQLKSLERQAEKAERykelkaelrelELALLVLRLEELREELEELQEELK----EAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    484 AKSHKdLEMKVQEIEK----LRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFsNEAKA 559
Cdd:TIGR02168  274 LEVSE-LEEEIEELQKelyaLANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL-EELKE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    560 QALQAQQREQELTQKIQQMETQHDKTESEqyllLTSQNTFLTKLKEECCLLAKKLEKVslksRSQIVRLSQEKRYLCDKL 639
Cdd:TIGR02168  352 ELESLEAELEELEAELEELESRLEELEEQ----LETLRSKVAQLELQIASLNNEIERL----EARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 29789245    640 EKLQKRNDELEEQCIQhgRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQLPSM 712
Cdd:TIGR02168  424 EELLKKLEEAELKELQ--AELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 228-519 3.07e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    228 ELERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSRVgglclkcaqheavlsqthsnVHIQ 307
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLA--------------------RLEA 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    308 TIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKS---ELERQTERLEKELA 384
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAA 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    385 SQQEKRAVEKEMIkKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEmdvtkvcgEMRFQ 464
Cdd:TIGR02168  821 NLRERLESLERRI-AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLE--------EALAL 891

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 29789245    465 LNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAA 519
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 364-631 3.54e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 3.54e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 364 QCEQLKSELERQTERLEKELASQQEKRAvEKEMIKKEVAREREDAESK---MLILSQNIAKLEAQVEKVTREKTAAVSHL 440
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEA-ELEELRLELEELELELEEAqaeEYELLAELARLEQDIARLEERRRELEERL 318

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 441 EEIQNHVASQEMDVTkvcgEMRFQLNKTKMEKDEVEKEHREyKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAAR 520
Cdd:COG1196 319 EELEEELAELEEELE----ELEEELEELEEELEEAEEELEE-AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 521 ARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFL 600
Cdd:COG1196 394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                       250       260       270
                ....*....|....*....|....*....|.
gi 29789245 601 TKLKEECCLLAKKLEKVSLKSRSQIVRLSQE 631
Cdd:COG1196 474 LLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 370-709 8.39e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.16  E-value: 8.39e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 370 SELERQTERLEKElASQQEK-RAVEKEMIKKEV---AREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQN 445
Cdd:COG1196 196 GELERQLEPLERQ-AEKAERyRELKEELKELEAellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 446 HVASQEMDVTkvcgemrfqlnktkmEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSEseqhvEQEQQKAARARQEC 525
Cdd:COG1196 275 ELEELELELE---------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEE-----LEEELAELEEELEE 334

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 526 LRVTELLGEAERQLHLTRLEkdsiqqsfsnEAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKE 605
Cdd:COG1196 335 LEEELEELEEELEEAEEELE----------EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 606 EccllakklekvslksRSQIVRLSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQLL 685
Cdd:COG1196 405 L---------------EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                       330       340
                ....*....|....*....|....
gi 29789245 686 NKQNQLLLERQNLSEEVARLRAQL 709
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARL 493
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 221-538 1.63e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 1.63e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 221 DANKWKLELERLKL---TYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAA--SASSRVGGLCLKCAQHEA 295
Cdd:COG1196 226 EAELLLLKLRELEAeleELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqAEEYELLAELARLEQDIA 305

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 296 VLSQTHSNVHiQTIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQ 375
Cdd:COG1196 306 RLEERRRELE-ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 376 TERLEKELASQQEKRAVEKEMIKKEVAREREDAEskmliLSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMdvt 455
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLER-----LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE--- 456

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 456 kvcgemrfQLNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEA 535
Cdd:COG1196 457 --------EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528


                ...
gi 29789245 536 ERQ 538
Cdd:COG1196 529 LIG 531
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 367-681 2.87e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 2.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    367 QLKSELERQTER---LEKELAS-QQEKRAVEKEMikKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEE 442
Cdd:TIGR02169  671 SEPAELQRLRERlegLKRELSSlQSELRRIENRL--DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    443 IQNHVASQemdvtkvcgemrfqlnktKMEKDEVEKEHREYKAKSHKdLEMKVQEIEKlrlelSESEQHVEQEQQKAARAR 522
Cdd:TIGR02169  749 LEQEIENV------------------KSELKELEARIEELEEDLHK-LEEALNDLEA-----RLSHSRIPEIQAELSKLE 804

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    523 QECLRVTELLGEAERQLHLTRLEKDSIQQSfsneakaqalqaqqrEQELTQKIQQMETQHDKTESEQYLLltsqNTFLTK 602
Cdd:TIGR02169  805 EEVSRIEARLREIEQKLNRLTLEKEYLEKE---------------IQELQEQRIDLKEQIKSIEKEIENL----NGKKEE 865

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 29789245    603 LKEEccllAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKRNDELEEQCiqhgrvhETMKERLRQLDKHGQATAQQL 681
Cdd:TIGR02169  866 LEEE----LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQI-------EKKRKRLSELKAKLEALEEEL 933
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
237-539 7.60e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 7.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  237 EAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAAsassrvgGLCLKCAQheavlsQTHSNVHIQTIERLTKER 316
Cdd:PRK02224 411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEA-------GKCPECGQ------PVEGSPHVETIEEDRERV 477

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  317 DDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEAnfEKTKALIQ-CEQLKSELERQTERLE--KELASQQEKRAVE 393
Cdd:PRK02224 478 EELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLE--ERREDLEElIAERRETIEEKRERAEelRERAAELEAEAEE 555

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  394 KEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTRektaAVSHLEEIQNhvasqemdvtkvCGEMRFQLNKTKMEKD 473
Cdd:PRK02224 556 KREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER----IRTLLAAIAD------------AEDEIERLREKREALA 619

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 29789245  474 EVEKEHREY---KAKSHKDLEMKVQE--IEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQL 539
Cdd:PRK02224 620 ELNDERRERlaeKRERKRELEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL 690
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 228-709 3.25e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 3.25e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 228 ELERLKLTYEAKTDLLES---QLMLLRKDLAEYQKTCEDLKERLKHKESLLAAsassrvgglclkcAQHEAVLSQTHSNV 304
Cdd:COG1196 268 ELEELRLELEELELELEEaqaEEYELLAELARLEQDIARLEERRRELEERLEE-------------LEEELAELEEELEE 334

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 305 HIQTIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEAN---FEKTKALIQCEQLKSELERQTERLEK 381
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAeelLEALRAAAELAAQLEELEEAEEALLE 414

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 382 ELASQQEKRAVEKEmIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVtkvcGEM 461
Cdd:COG1196 415 RLERLEEELEELEE-ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL----AEA 489

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 462 RFQLNKTKMEKDEVEKEHREYKAKSHKD------------LEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECL--- 526
Cdd:COG1196 490 AARLLLLLEAEADYEGFLEGVKAALLLAglrglagavavlIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLkaa 569

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 527 ---RVTELLGEAERQLHLTRLEKDSIQQSFSN----------EAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLL 593
Cdd:COG1196 570 kagRATFLPLDKIRARAALAAALARGAIGAAVdlvasdlreaDARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV 649

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 594 TSQNT-----------FLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHET 662
Cdd:COG1196 650 TLEGEggsaggsltggSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                       490       500       510       520
                ....*....|....*....|....*....|....*....|....*..
gi 29789245 663 MKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQL 709
Cdd:COG1196 730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 125-435 9.03e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 9.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    125 QSQYIHHLEAEVKFCKDELSGMKNRVQVVVLENERLQQELKS--QRPEETLREQTFLDASGNMQNSWIMTREDsRVDEAA 202
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQlrKELEELSRQISALRKDLARLEAEVEQLEE-RIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    203 KRPFSHGDAETGKTASTGDANKWKLELERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSR 282
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    283 VgglclKCAQHEAVLSQTHSNVHiQTIERLTKERDDL----------MSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTE 352
Cdd:TIGR02168  834 A-----ATERRLEDLEEQIEELS-EDIESLAAEIEELeelieeleseLEALLNERASLEEALALLRSELEELSEELRELE 907

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    353 EANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMikkevarEREDAESKMLILSQNIAKLEAQVEKVTRE 432
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL-------TLEEAEALENKIEDDEEEARRRLKRLENK 980


                   ...
gi 29789245    433 KTA 435
Cdd:TIGR02168  981 IKE 983
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
237-432 9.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 9.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  237 EAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAAsassrvgglCLKCAQHEAVLSQTHSnvHIQTIERLTKER 316
Cdd:COG4913  609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREA---------LQRLAEYSWDEIDVAS--AEREIAELEAEL 677

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  317 DDL---MSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRaVE 393
Cdd:COG4913  678 ERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER-FA 756

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 29789245  394 KEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTRE 432
Cdd:COG4913  757 AALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 310-664 1.26e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   310 ERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEK 389
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   390 RAVEKEMIKKEVAREREDAESKmlilsQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTK 469
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKA-----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK 1397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   470 MEKDEVEKEHREYKAKS---HKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEK 546
Cdd:PTZ00121 1398 KKAEEDKKKADELKKAAaakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKK 1477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   547 DSIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIV 626
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 29789245   627 RLSQEKRYLCDKLEKLQKRNDEL----EEQCIQHGRVHETMK 664
Cdd:PTZ00121 1558 KKAEEKKKAEEAKKAEEDKNMALrkaeEAKKAEEARIEEVMK 1599
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 228-451 1.81e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    228 ELERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKE---------------SLLAASASSRVGGLCLKCAQ 292
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEqqkqilrerlanlerQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    293 HEAVLSQTHSNVHIQTIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSEL 372
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 29789245    373 ERQTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQE 451
Cdd:TIGR02168  417 ERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 495-709 1.91e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 1.91e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 495 QEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFsNEAKAQALQAQQREQELTQK 574
Cdd:COG4942  27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL-AELEKEIAELRAELEAQKEE 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 575 IQQMETQHDKTESEQYL-LLTSQNTFLTKLKeecclLAKKLEKVSLKSRSQIVRLSQEkrylcdkLEKLQKRNDELEEQC 653
Cdd:COG4942 106 LAELLRALYRLGRQPPLaLLLSPEDFLDAVR-----RLQYLKYLAPARREQAEELRAD-------LAELAALRAELEAER 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 29789245 654 IQHGRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQL 709
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
PTZ00121 PTZ00121
MAEBL; Provisional
 331-585 2.51e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 2.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   331 AEAQKR--ETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEK-ELASQQEKRAVEKEM--------IKK 399
Cdd:PTZ00121 1530 AEEAKKadEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKaEEAKKAEEARIEEVMklyeeekkMKA 1609

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   400 EVAREREDAESKMLILSQNiAKLEAQVEKVTREKTAAVSHLEEIQNhvASQEMDVTKVCGEMRFQLNKTKME---KDEVE 476
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELKK--AEEENKIKAAEEAKKAEEDKKKAEeakKAEED 1686

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   477 KEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNE 556
Cdd:PTZ00121 1687 EKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                         250       260       270
                  ....*....|....*....|....*....|...
gi 29789245   557 AKAQALQAQQR----EQELTQKIQQMETQHDKT 585
Cdd:PTZ00121 1767 EKKAEEIRKEKeaviEEELDEEDEKRRMEVDKK 1799
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 228-409 2.88e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 2.88e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 228 ELERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKhkESLLAASASSRVGGLCLKCAQHEAvlsqTHSNVHIQ 307
Cdd:COG4942  66 ALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA--ELLRALYRLGRQPPLALLLSPEDF----LDAVRRLQ 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 308 TIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQ 387
Cdd:COG4942 140 YLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219

                       170       180
                ....*....|....*....|..
gi 29789245 388 EKRAVEKEMIKKEVAREREDAE 409
Cdd:COG4942 220 QEAEELEALIARLEAEAAAAAE 241
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 357-669 3.53e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 40.73  E-value: 3.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    357 EKTKALIQCEQLK-SELERQTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQN--IAKLEAQVEKVTREK 433
Cdd:pfam02463  170 KKKEALKKLIEETeNLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLklNEERIDLLQELLRDE 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    434 TAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSES---EQH 510
Cdd:pfam02463  250 QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKkkaEKE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    511 VEQEQQKAARARQECLRVTELLG-------EAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHD 583
Cdd:pfam02463  330 LKKEKEEIEELEKELKELEIKREaeeeeeeELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245    584 KTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETM 663
Cdd:pfam02463  410 LLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELL 489


                   ....*.
gi 29789245    664 KERLRQ 669
Cdd:pfam02463  490 LSRQKL 495
PTZ00121 PTZ00121
MAEBL; Provisional
 314-523 3.76e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   314 KERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVE 393
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245   394 KEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVcgEMRFQLNKTKMEKD 473
Cdd:PTZ00121 1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA--KKEAEEDKKKAEEA 1749

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 29789245   474 EVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQ 523
Cdd:PTZ00121 1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
357-709 3.84e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 3.84e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 357 EKTKALIQCEQLKSELERQTERLEKELAS-QQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTA 435
Cdd:COG4717  85 EKEEEYAELQEELEELEEELEELEAELEElREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEE 164

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 436 AVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAKShKDLEMKVQEIEKlRLELSESEQHVEQEQ 515
Cdd:COG4717 165 LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEEL-EEAQEELEELEE-ELEQLENELEAAALE 242

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 516 QKAARARQECLRVTELLGEAERQLHLTRLEKD------------SIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHD 583
Cdd:COG4717 243 ERLKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlgllALLFLLLAREKASLGKEAEELQALPALEELEEEELE 322

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 584 KTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVS-LKSRSQIVRLSQEKRYLCD------------KLEKLQKRNDELE 650
Cdd:COG4717 323 ELLAALGLPPDLSPEELLELLDRIEELQELLREAEeLEEELQLEELEQEIAALLAeagvedeeelraALEQAEEYQELKE 402

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 651 EQCIQHGRVHETMKERLRQLDKHGQAT-AQQLVQLLNKQNQLLLERQNLSEEVARLRAQL 709
Cdd:COG4717 403 ELEELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEELEELREELAELEAEL 462
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 295-538 4.57e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.13  E-value: 4.57e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 295 AVLSQTHSNVHIQTIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANfektKALIQCEQLKSELER 374
Cdd:COG4942   8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEA 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 375 QTERLEKELASQQEKRAVEKEMIKKEVA---REREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQE 451
Cdd:COG4942  84 ELAELEKEIAELRAELEAQKEELAELLRalyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 452 mdvtkvcgEMRFQLNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTEL 531
Cdd:COG4942 164 --------ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                ....*..
gi 29789245 532 LGEAERQ 538
Cdd:COG4942 236 AAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
309-445 5.04e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.28  E-value: 5.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  309 IERLTKERDDLMSVLVSVRSSLAEAQkRETSAYEQVKHAVQMTEEANFEktkaLIQCEQLKSELERQTERLEKELASQQE 388
Cdd:COG4913  612 LAALEAELAELEEELAEAEERLEALE-AELDALQERREALQRLAEYSWD----EIDVASAEREIAELEAELERLDASSDD 686

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 29789245  389 KRAVEKEmiKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQN 445
Cdd:COG4913  687 LAALEEQ--LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED 741
PRK12704 PRK12704
phosphodiesterase; Provisional
 333-443 5.49e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.76  E-value: 5.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245  333 AQKRETSAYEQVKHAVQMTE-EANFEKTKALIQC----EQLKSELERQTERLEKELAsQQEKRAVEKEMI----KKEVAR 403
Cdd:PRK12704  29 AEAKIKEAEEEAKRILEEAKkEAEAIKKEALLEAkeeiHKLRNEFEKELRERRNELQ-KLEKRLLQKEENldrkLELLEK 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 29789245  404 EREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEI 443
Cdd:PRK12704 108 REEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERI 147
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 367-581 5.98e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.75  E-value: 5.98e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 367 QLKSELERQTERLEKELASQQEKRAVEKEMiKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNH 446
Cdd:COG4942  20 DAAAEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 447 VASQEMDVTKVCGEM-----------------------RFQLNKTKMEKDeveKEHREYKAKSHKDLEMKVQEIEKLRLE 503
Cdd:COG4942  99 LEAQKEELAELLRALyrlgrqpplalllspedfldavrRLQYLKYLAPAR---REQAEELRADLAELAALRAELEAERAE 175

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 29789245 504 LSESEQHVEQEQQKAARARQEclrVTELLGEAERQLHLTRLEKDSIQQSfsneakaqalqaqqrEQELTQKIQQMETQ 581
Cdd:COG4942 176 LEALLAELEEERAALEALKAE---RQKLLARLEKELAELAAELAELQQE---------------AEELEALIARLEAE 235
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
229-432 6.36e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.00  E-value: 6.36e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 229 LERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKErlkhkesllaasassrvgglclkcaQHEAVLSQTHSNVHIQT 308
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQ-------------------------KNGLVDLSEEAKLLLQQ 220

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 309 IERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKtkaliQCEQLKSELERQTERLEKE---LAS 385
Cdd:COG3206 221 LSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRA-----QLAELEAELAELSARYTPNhpdVIA 295

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 29789245 386 QQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTRE 432
Cdd:COG3206 296 LRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR 342
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 348-581 7.87e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 39.56  E-value: 7.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 348 VQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVE 427
Cdd:COG5185 274 AESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLT 353

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29789245 428 KVTREKTAAVSHLEEIQNHVASQEmdvtkvcgemrfqlnKTKMEKDEVEKEHREYKAKsHKDLEMKVQEI-EKLRLELSE 506
Cdd:COG5185 354 ENLEAIKEEIENIVGEVELSKSSE---------------ELDSFKDTIESTKESLDEI-PQNQRGYAQEIlATLEDTLKA 417

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 29789245 507 SEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSF-SNEAKAQALQAQQREQELTQKIQQMETQ 581
Cdd:COG5185 418 ADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRlEEAYDEINRSVRSKKEDLNEELTQIESR 493
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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