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Conserved domains on  [gi|14165280|ref|NP_115789|]
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normal mucosa of esophagus-specific gene 1 protein [Homo sapiens]

Protein Classification

NDUFA4 family protein( domain architecture ID 10534779)

NDUFA4 family protein similar to Homo sapiens NADH-ubiquinone oxidoreductase MLRQ subunit and normal mucosa of esophagus-specific gene 1 protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
B12D pfam06522
NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial ...
 9-76 4.59e-25

NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial NADH-ubiquinone reductase complex I is nuclear and is found in plants, insects, fungi and higher metazoans. It appears to act within the membrane and, in mammals, is highly expressed in muscle and neural tissue, indicative of a role in ATP generation.


:

Pssm-ID: 461937  Cd Length: 69  Bit Score: 88.41  E-value: 4.59e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 14165280    9 KRKELIPLVVFMTVAAGGASSFAVY-SLWKTDVILDRKKNPEPWETVDPTVPQKLITINQQWKPIEELQ 76
Cdd:pfam06522  1 KRPELIPLFVAIGAAVGGAVFYLLRlLLTNPDVRWNKKNNPEPWNVLDNNKEGKFYSINRDYSKLKKPA 69
 
Name Accession Description Interval E-value
B12D pfam06522
NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial ...
 9-76 4.59e-25

NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial NADH-ubiquinone reductase complex I is nuclear and is found in plants, insects, fungi and higher metazoans. It appears to act within the membrane and, in mammals, is highly expressed in muscle and neural tissue, indicative of a role in ATP generation.


Pssm-ID: 461937  Cd Length: 69  Bit Score: 88.41  E-value: 4.59e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 14165280    9 KRKELIPLVVFMTVAAGGASSFAVY-SLWKTDVILDRKKNPEPWETVDPTVPQKLITINQQWKPIEELQ 76
Cdd:pfam06522  1 KRPELIPLFVAIGAAVGGAVFYLLRlLLTNPDVRWNKKNNPEPWNVLDNNKEGKFYSINRDYSKLKKPA 69
 
Name Accession Description Interval E-value
B12D pfam06522
NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial ...
 9-76 4.59e-25

NADH-ubiquinone reductase complex 1 MLRQ subunit; The MLRQ subunit of mitochondrial NADH-ubiquinone reductase complex I is nuclear and is found in plants, insects, fungi and higher metazoans. It appears to act within the membrane and, in mammals, is highly expressed in muscle and neural tissue, indicative of a role in ATP generation.


Pssm-ID: 461937  Cd Length: 69  Bit Score: 88.41  E-value: 4.59e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 14165280    9 KRKELIPLVVFMTVAAGGASSFAVY-SLWKTDVILDRKKNPEPWETVDPTVPQKLITINQQWKPIEELQ 76
Cdd:pfam06522  1 KRPELIPLFVAIGAAVGGAVFYLLRlLLTNPDVRWNKKNNPEPWNVLDNNKEGKFYSINRDYSKLKKPA 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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