NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|16923976|ref|NP_476466|]
View 

peroxisomal ATPase PEX6 [Rattus norvegicus]

Protein Classification

CDC48 family AAA ATPase( domain architecture ID 1001098)

CDC48 family AAA ATPase is involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus; similar to yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CDC48 super family cl36852
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 466-975 6.83e-96

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


The actual alignment was detected with superfamily member TIGR01243:

Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 319.16  E-value: 6.83e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGL-GE- 543
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVtGEv 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   544 DARVVATLRHLLldeDPLSRCPPLMVVATTSRVQDLPTDVRTA--FPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLS 621
Cdd:TIGR01243 295 EKRVVAQLLTLM---DGLKGRGRVIVIGATNRPDALDPALRRPgrFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLD 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   622 QLARRCAGFVVGDLYALLTHASRAACTR-IKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGApKIPSV 700
Cdd:TIGR01243 372 KLAEVTHGFVGADLAALAKEAAMAALRRfIREGKINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLV-EVPNV 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   701 SWHDVGGLQDVKKEILETIQLPLEHPEL--LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQ 778
Cdd:TIGR01243 451 RWSDIGGLEEVKQELREAVEWPLKHPEIfeKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   779 SEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLR 858
Cdd:TIGR01243 531 SEKAIREIFRKARQAAPAIIFFDEIDAIAPARGARFDT-SVTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   859 PGRFDKLVFVGASEDRAsQLRVLSAITRKFKLEASVSLMNvLDCCPPQLTGADLYSLCSDAMMTALKRRVRD-----LEE 933
Cdd:TIGR01243 610 PGRFDRLILVPPPDEEA-RKEIFKIHTRSMPLAEDVDLEE-LAEMTEGYTGADIEAVCREAAMAALRESIGSpakekLEV 687

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 16923976   934 GLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 975
Cdd:TIGR01243 688 GEEEFLKDLKVEMRHFLEALKKVKPSVSKEDMLRYERLAKEL 729
 
Name Accession Description Interval E-value
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 466-975 6.83e-96

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 319.16  E-value: 6.83e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGL-GE- 543
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVtGEv 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   544 DARVVATLRHLLldeDPLSRCPPLMVVATTSRVQDLPTDVRTA--FPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLS 621
Cdd:TIGR01243 295 EKRVVAQLLTLM---DGLKGRGRVIVIGATNRPDALDPALRRPgrFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLD 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   622 QLARRCAGFVVGDLYALLTHASRAACTR-IKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGApKIPSV 700
Cdd:TIGR01243 372 KLAEVTHGFVGADLAALAKEAAMAALRRfIREGKINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLV-EVPNV 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   701 SWHDVGGLQDVKKEILETIQLPLEHPEL--LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQ 778
Cdd:TIGR01243 451 RWSDIGGLEEVKQELREAVEWPLKHPEIfeKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   779 SEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLR 858
Cdd:TIGR01243 531 SEKAIREIFRKARQAAPAIIFFDEIDAIAPARGARFDT-SVTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   859 PGRFDKLVFVGASEDRAsQLRVLSAITRKFKLEASVSLMNvLDCCPPQLTGADLYSLCSDAMMTALKRRVRD-----LEE 933
Cdd:TIGR01243 610 PGRFDRLILVPPPDEEA-RKEIFKIHTRSMPLAEDVDLEE-LAEMTEGYTGADIEAVCREAAMAALRESIGSpakekLEV 687

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 16923976   934 GLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 975
Cdd:TIGR01243 688 GEEEFLKDLKVEMRHFLEALKKVKPSVSKEDMLRYERLAKEL 729
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 694-962 1.22e-90

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 291.91  E-value: 1.22e-90
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 694 APKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLL--HGPPGTGKTLLAKAVATECSLTFLSVKGPEL 771
Cdd:COG1222  69 PAESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVllYGPPGTGKTLLAKAVAGELGAPFIRVRGSEL 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 772 INMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVmDRVVSQLLAELDGLHSTQDVFVIGATNRPDL 851
Cdd:COG1222 149 VSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGTSGEV-QRTVNQLLAELDGFESRGDVLIIAATNRPDL 227

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 852 LDPALLRPGRFDKLVFVGASeDRASQLRVLSAITRKFKLEASV---SLMNVLDccppQLTGADLYSLCSDAMMTALKRRV 928
Cdd:COG1222 228 LDPALLRPGRFDRVIEVPLP-DEEAREEILKIHLRDMPLADDVdldKLAKLTE----GFSGADLKAIVTEAGMFAIREGR 302

                       250       260       270
                ....*....|....*....|....*....|....
gi 16923976 929 RDleegleprssallLTMEDLLQAAARLQPSVSE 962
Cdd:COG1222 303 DT-------------VTMEDLEKAIEKVKKKTET 323
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 711-868 2.88e-86

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 273.62  E-value: 2.88e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFAR 789
Cdd:cd19527   1 VKKEILDTIQLPLEHPELfSSGLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQK 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 790 ARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHST-QDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19527  81 ARDAKPCVIFFDELDSLAPSRGNSGDSGGVMDRVVSQLLAELDGMSSSgQDVFVIGATNRPDLLDPALLRPGRFDKLLYL 160
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 698-952 5.79e-64

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 221.24  E-value: 5.79e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  698 PSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMY 775
Cdd:PRK03992 126 PNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVgiEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKF 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  776 VGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGgvmDRVVS----QLLAELDGLHSTQDVFVIGATNRPDL 851
Cdd:PRK03992 206 IGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRTDSGTSG---DREVQrtlmQLLAEMDGFDPRGNVKIIAATNRIDI 282

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  852 LDPALLRPGRFDKLVFVGASeDRASQLRVLSAITRKFKLEASVSLMNVLDCCpPQLTGADLYSLCSDAMMTALKRRvRDl 931
Cdd:PRK03992 283 LDPAILRPGRFDRIIEVPLP-DEEGRLEILKIHTRKMNLADDVDLEELAELT-EGASGADLKAICTEAGMFAIRDD-RT- 358

                        250       260
                 ....*....|....*....|.
gi 16923976  932 eegleprssalLLTMEDLLQA 952
Cdd:PRK03992 359 -----------EVTMEDFLKA 368
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 741-869 3.85e-53

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 181.25  E-value: 3.85e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   741 HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSggVM 820
Cdd:pfam00004   4 YGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDS--ES 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 16923976   821 DRVVSQLLAELDGL-HSTQDVFVIGATNRPDLLDPALLrpGRFDKLVFVG 869
Cdd:pfam00004  82 RRVVNQLLTELDGFtSSNSKVIVIAATNRPDKLDPALL--GRFDRIIEFP 129
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 741-872 3.85e-17

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 79.34  E-value: 3.85e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976    741 HGPPGTGKTLLAKAVATECSLTFLSVK-----------------GPELINMYVGQSEENVREVFARARAAAPCIIFFDEL 803
Cdd:smart00382   8 VGPPGSGKTTLARALARELGPPGGGVIyidgedileevldqlllIIVGGKKASGSGELRLRLALALARKLKPDVLILDEI 87

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976    804 DSLApsrgrsgDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPgRFDKLVFVGASE 872
Cdd:smart00382  88 TSLL-------DAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLLLIL 148
 
Name Accession Description Interval E-value
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 466-975 6.83e-96

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 319.16  E-value: 6.83e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGL-GE- 543
Cdd:TIGR01243 215 VLLYGPPGTGKTLLAKAVANEAGAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVtGEv 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   544 DARVVATLRHLLldeDPLSRCPPLMVVATTSRVQDLPTDVRTA--FPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLS 621
Cdd:TIGR01243 295 EKRVVAQLLTLM---DGLKGRGRVIVIGATNRPDALDPALRRPgrFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLD 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   622 QLARRCAGFVVGDLYALLTHASRAACTR-IKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGApKIPSV 700
Cdd:TIGR01243 372 KLAEVTHGFVGADLAALAKEAAMAALRRfIREGKINFEAEEIPAEVLKELKVTMKDFMEALKMVEPSAIREVLV-EVPNV 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   701 SWHDVGGLQDVKKEILETIQLPLEHPEL--LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQ 778
Cdd:TIGR01243 451 RWSDIGGLEEVKQELREAVEWPLKHPEIfeKMGIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGE 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   779 SEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLR 858
Cdd:TIGR01243 531 SEKAIREIFRKARQAAPAIIFFDEIDAIAPARGARFDT-SVTDRIVNQLLTEMDGIQELSNVVVIAATNRPDILDPALLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   859 PGRFDKLVFVGASEDRAsQLRVLSAITRKFKLEASVSLMNvLDCCPPQLTGADLYSLCSDAMMTALKRRVRD-----LEE 933
Cdd:TIGR01243 610 PGRFDRLILVPPPDEEA-RKEIFKIHTRSMPLAEDVDLEE-LAEMTEGYTGADIEAVCREAAMAALRESIGSpakekLEV 687

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|..
gi 16923976   934 GLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 975
Cdd:TIGR01243 688 GEEEFLKDLKVEMRHFLEALKKVKPSVSKEDMLRYERLAKEL 729
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 694-962 1.22e-90

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 291.91  E-value: 1.22e-90
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 694 APKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLL--HGPPGTGKTLLAKAVATECSLTFLSVKGPEL 771
Cdd:COG1222  69 PAESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYGIEPPKGVllYGPPGTGKTLLAKAVAGELGAPFIRVRGSEL 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 772 INMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVmDRVVSQLLAELDGLHSTQDVFVIGATNRPDL 851
Cdd:COG1222 149 VSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDGTSGEV-QRTVNQLLAELDGFESRGDVLIIAATNRPDL 227

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 852 LDPALLRPGRFDKLVFVGASeDRASQLRVLSAITRKFKLEASV---SLMNVLDccppQLTGADLYSLCSDAMMTALKRRV 928
Cdd:COG1222 228 LDPALLRPGRFDRVIEVPLP-DEEAREEILKIHLRDMPLADDVdldKLAKLTE----GFSGADLKAIVTEAGMFAIREGR 302

                       250       260       270
                ....*....|....*....|....*....|....
gi 16923976 929 RDleegleprssallLTMEDLLQAAARLQPSVSE 962
Cdd:COG1222 303 DT-------------VTMEDLEKAIEKVKKKTET 323
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 711-868 2.88e-86

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 273.62  E-value: 2.88e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFAR 789
Cdd:cd19527   1 VKKEILDTIQLPLEHPELfSSGLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQK 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 790 ARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHST-QDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19527  81 ARDAKPCVIFFDELDSLAPSRGNSGDSGGVMDRVVSQLLAELDGMSSSgQDVFVIGATNRPDLLDPALLRPGRFDKLLYL 160
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 711-868 4.05e-76

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 246.04  E-value: 4.05e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPELLSLGLRRSGL--LLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFA 788
Cdd:cd19511   1 VKRELKEAVEWPLKHPDAFKRLGIRPPKgvLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQ 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 789 RARAAAPCIIFFDELDSLAPSRGRSgDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19511  81 KARQAAPCIIFFDEIDSLAPRRGQS-DSSGVTDRVVSQLLTELDGIESLKGVVVIAATNRPDMIDPALLRPGRLDKLIYV 159
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
 711-868 1.02e-73

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 239.72  E-value: 1.02e-73
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPELLSL--GLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFA 788
Cdd:cd19528   1 VKRELQELVQYPVEHPDKFLKfgMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 789 RARAAAPCIIFFDELDSLAPSRGRS-GDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVF 867
Cdd:cd19528  81 KARAAAPCVLFFDELDSIAKARGGNiGDAGGAADRVINQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGRLDQLIY 160


                .
gi 16923976 868 V 868
Cdd:cd19528 161 I 161
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 545-955 1.28e-67

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 231.72  E-value: 1.28e-67
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 545 ARVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLPTDVRTAFPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLSQLA 624
Cdd:COG0464   8 AVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLALLAALLS 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 625 R-RCAGFVVGDLYALLTHASRAACTRIKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAvgapkipsvsWH 703
Cdd:COG0464  88 AlELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAI----------LD 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLL--HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEE 781
Cdd:COG0464 158 DLGGLEEVKEELRELVALPLKRPELREEYGLPPPRGLllYGPPGTGKTLLARALAGELGLPLIEVDLSDLVSKYVGETEK 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 782 NVREVFARARAAAPCIIFFDELDSLAPSRGRSGDsgGVMDRVVSQLLAELDGLHStqDVFVIGATNRPDLLDPALLRpgR 861
Cdd:COG0464 238 NLREVFDKARGLAPCVLFIDEADALAGKRGEVGD--GVGRRVVNTLLTEMEELRS--DVVVIAATNRPDLLDPALLR--R 311

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 862 FDKLVFVGASeDRASQLRVLSAITRKFKLEASVSLMNVLDCCpPQLTGADLYSLCSDAMMTALkrrvrdleeglepRSSA 941
Cdd:COG0464 312 FDEIIFFPLP-DAEERLEIFRIHLRKRPLDEDVDLEELAEAT-EGLSGADIRNVVRRAALQAL-------------RLGR 376

                       410
                ....*....|....
gi 16923976 942 LLLTMEDLLQAAAR 955
Cdd:COG0464 377 EPVTTEDLLEALER 390
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
 711-868 6.44e-65

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 215.44  E-value: 6.44e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPELLSLGLRRSGL--LLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFA 788
Cdd:cd19529   1 VKQELKEAVEWPLLKPEVFKRLGIRPPKgiLLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFR 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 789 RARAAAPCIIFFDELDSLAPSRGRSGDSgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19529  81 KARQVAPCVIFFDEIDSIAPRRGTTGDS-GVTERVVNQLLTELDGLEEMNGVVVIAATNRPDIIDPALLRAGRFDRLIYI 159
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 698-952 5.79e-64

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 221.24  E-value: 5.79e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  698 PSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMY 775
Cdd:PRK03992 126 PNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVgiEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKF 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  776 VGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGgvmDRVVS----QLLAELDGLHSTQDVFVIGATNRPDL 851
Cdd:PRK03992 206 IGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRTDSGTSG---DREVQrtlmQLLAEMDGFDPRGNVKIIAATNRIDI 282

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  852 LDPALLRPGRFDKLVFVGASeDRASQLRVLSAITRKFKLEASVSLMNVLDCCpPQLTGADLYSLCSDAMMTALKRRvRDl 931
Cdd:PRK03992 283 LDPAILRPGRFDRIIEVPLP-DEEGRLEILKIHTRKMNLADDVDLEELAELT-EGASGADLKAICTEAGMFAIRDD-RT- 358

                        250       260
                 ....*....|....*....|.
gi 16923976  932 eegleprssalLLTMEDLLQA 952
Cdd:PRK03992 359 -----------EVTMEDFLKA 368
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 711-867 2.21e-63

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 211.13  E-value: 2.21e-63
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPE--LLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFA 788
Cdd:cd19526   1 VKKALEETIEWPSKYPKifASSPLRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFS 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976 789 RARAAAPCIIFFDELDSLAPSRGRsgDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVF 867
Cdd:cd19526  81 RAQSAKPCILFFDEFDSIAPKRGH--DSTGVTDRVVNQLLTQLDGVEGLDGVYVLAATSRPDLIDPALLRPGRLDKLVY 157
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 696-959 6.29e-61

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 221.70  E-value: 6.29e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   696 KIPSVSWHDVGGLQDVKKEILETIQLPLEHPE--LLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELIN 773
Cdd:TIGR01243 171 KVPKVTYEDIGGLKEAKEKIREMVELPMKHPElfEHLGIEPPKGVLLYGPPGTGKTLLAKAVANEAGAYFISINGPEIMS 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   774 MYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSgdSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLD 853
Cdd:TIGR01243 251 KYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEV--TGEVEKRVVAQLLTLMDGLKGRGRVIVIGATNRPDALD 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   854 PALLRPGRFDKLVFVGASEDRASQlRVLSAITRKFKLEASVSLMNVLDCCpPQLTGADLYSLCSDAMMTALKRRVRDLEE 933
Cdd:TIGR01243 329 PALRRPGRFDREIVIRVPDKRARK-EILKVHTRNMPLAEDVDLDKLAEVT-HGFVGADLAALAKEAAMAALRRFIREGKI 406

                         250       260       270
                  ....*....|....*....|....*....|..
gi 16923976   934 GLEPRS------SALLLTMEDLLQAAARLQPS 959
Cdd:TIGR01243 407 NFEAEEipaevlKELKVTMKDFMEALKMVEPS 438
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 708-868 1.78e-60

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 203.10  E-value: 1.78e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 708 LQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVRE 785
Cdd:cd19530   1 LDHVREELTMSILRPIKRPDIYKALgiDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQ 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 786 VFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVmdRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKL 865
Cdd:cd19530  81 VFQRARASAPCVIFFDEVDALVPKRGDGGSWASE--RVVNQLLTEMDGLEERSNVFVIAATNRPDIIDPAMLRPGRLDKT 158


                ...
gi 16923976 866 VFV 868
Cdd:cd19530 159 LYV 161
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 704-866 4.17e-60

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 202.52  E-value: 4.17e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPELLSLGLRRSG--LLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEE 781
Cdd:cd19503   1 DIGGLDEQIASLKELIELPLKYPELFRALGLKPPrgVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEK 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 782 NVREVFARARAAAPCIIFFDELDSLAPSRGRsgDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGR 861
Cdd:cd19503  81 NLREIFEEARSHAPSIIFIDEIDALAPKREE--DQREVERRVVAQLLTLMDGMSSRGKVVVIAATNRPDAIDPALRRPGR 158


                ....*
gi 16923976 862 FDKLV 866
Cdd:cd19503 159 FDREV 163
26Sp45 TIGR01242
26S proteasome subunit P45 family; Many proteins may score above the trusted cutoff because an ...
 698-952 1.29e-59

26S proteasome subunit P45 family; Many proteins may score above the trusted cutoff because an internal


Pssm-ID: 130309 [Multi-domain]  Cd Length: 364  Bit Score: 208.50  E-value: 1.29e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   698 PSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMY 775
Cdd:TIGR01242 117 PNVSYEDIGGLEEQIREIREAVELPLKHPELFEEVgiEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVRKY 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   776 VGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGG-VMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDP 854
Cdd:TIGR01242 197 IGEGARLVREIFELAKEKAPSIIFIDEIDAIAAKRTDSGTSGDrEVQRTLMQLLAELDGFDPRGNVKVIAATNRPDILDP 276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   855 ALLRPGRFDKLVFVGASEDRAsQLRVLSAITRKFKLEASVSLMNVldccpPQLT----GADLYSLCSDAMMTALKRRVRd 930
Cdd:TIGR01242 277 ALLRPGRFDRIIEVPLPDFEG-RLEILKIHTRKMKLAEDVDLEAI-----AKMTegasGADLKAICTEAGMFAIREERD- 349

                         250       260
                  ....*....|....*....|..
gi 16923976   931 leegleprssalLLTMEDLLQA 952
Cdd:TIGR01242 350 ------------YVTMDDFIKA 359
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 701-866 6.33e-56

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 191.01  E-value: 6.33e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 701 SWHDVGGLQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQ 778
Cdd:cd19502   1 TYEDIGGLDEQIREIREVVELPLKHPELFEELgiEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 779 SEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGgvmDRVVS----QLLAELDGLHSTQDVFVIGATNRPDLLDP 854
Cdd:cd19502  81 GARLVRELFEMAREKAPSIIFIDEIDAIGAKRFDSGTGG---DREVQrtmlELLNQLDGFDPRGNIKVIMATNRPDILDP 157

                       170
                ....*....|..
gi 16923976 855 ALLRPGRFDKLV 866
Cdd:cd19502 158 ALLRPGRFDRKI 169
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 711-868 2.61e-54

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 185.95  E-value: 2.61e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 711 VKKEILETIQLPLEHPELLSLGLRRSGLLL-HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFAR 789
Cdd:cd19481   1 LKASLREAVEAPRRGSRLRRYGLGLPKGILlYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFER 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976 790 ARAAAPCIIFFDELDSLAPSRGRSGDSgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19481  81 ARRLAPCILFIDEIDAIGRKRDSSGES-GELRRVLNQLLTELDGVNSRSKVLVIAATNRPDLLDPALLRPGRFDEVIEF 158
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
 704-869 2.99e-53

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 183.02  E-value: 2.99e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPE--LLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEE 781
Cdd:cd19519   1 DIGGCRKQLAQIREMVELPLRHPElfKAIGIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESES 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 782 NVREVFARARAAAPCIIFFDELDSLAPSRGRSgdSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGR 861
Cdd:cd19519  81 NLRKAFEEAEKNAPAIIFIDEIDAIAPKREKT--HGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGR 158


                ....*...
gi 16923976 862 FDKLVFVG 869
Cdd:cd19519 159 FDREIDIG 166
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 741-869 3.85e-53

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 181.25  E-value: 3.85e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   741 HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSggVM 820
Cdd:pfam00004   4 YGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDS--ES 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 16923976   821 DRVVSQLLAELDGL-HSTQDVFVIGATNRPDLLDPALLrpGRFDKLVFVG 869
Cdd:pfam00004  82 RRVVNQLLTELDGFtSSNSKVIVIAATNRPDKLDPALL--GRFDRIIEFP 129
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 700-868 4.06e-51

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 177.42  E-value: 4.06e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 700 VSWHDVGGLQDVKKEILETIQLpLEHPELLSLGLRRSG--LLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVG 777
Cdd:cd19501   1 VTFKDVAGCEEAKEELKEVVEF-LKNPEKFTKLGAKIPkgVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 778 QSEENVREVFARARAAAPCIIFFDELDSLAPSRGR-SGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPAL 856
Cdd:cd19501  80 VGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGAgLGGGHDEREQTLNQLLVEMDGFESNTGVIVIAATNRPDVLDPAL 159

                       170
                ....*....|..
gi 16923976 857 LRPGRFDKLVFV 868
Cdd:cd19501 160 LRPGRFDRQVYV 171
FtsH_fam TIGR01241
ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct ...
 698-939 4.48e-51

ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 273520 [Multi-domain]  Cd Length: 495  Bit Score: 187.88  E-value: 4.48e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   698 PSVSWHDVGGLQDVKKEILETIQLpLEHPE--LLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMY 775
Cdd:TIGR01241  50 PKVTFKDVAGIDEAKEELMEIVDF-LKNPSkfTKLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMF 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   776 VGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRsGDSGG--VMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLD 853
Cdd:TIGR01241 129 VGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGA-GLGGGndEREQTLNQLLVEMDGFGTNTGVIVIAATNRPDVLD 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   854 PALLRPGRFDKLVFVGASE--DRASQLRVLSaitRKFKLEASVSLMNVLDCCpPQLTGADLYSLCSDAMMTALKR----- 926
Cdd:TIGR01241 208 PALLRPGRFDRQVVVDLPDikGREEILKVHA---KNKKLAPDVDLKAVARRT-PGFSGADLANLLNEAALLAARKnktei 283

                         250       260
                  ....*....|....*....|
gi 16923976   927 RVRDLEE-------GLEPRS 939
Cdd:TIGR01241 284 TMNDIEEaidrviaGPEKKS 303
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 690-934 4.68e-48

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 176.49  E-value: 4.68e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  690 QAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVK 767
Cdd:PTZ00454 132 QLLQMSEKPDVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIgiDPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVV 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  768 GPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSR--GRSGDSGGVmDRVVSQLLAELDGLHSTQDVFVIGA 845
Cdd:PTZ00454 212 GSEFVQKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRfdAQTGADREV-QRILLELLNQMDGFDQTTNVKVIMA 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  846 TNRPDLLDPALLRPGRFD-KLVFvgASEDRASQLRVLSAITRKFKLEASVSLMNVLDcCPPQLTGADLYSLCSDAMMTAL 924
Cdd:PTZ00454 291 TNRADTLDPALLRPGRLDrKIEF--PLPDRRQKRLIFQTITSKMNLSEEVDLEDFVS-RPEKISAADIAAICQEAGMQAV 367

                        250
                 ....*....|....*
gi 16923976  925 K--RRV---RDLEEG 934
Cdd:PTZ00454 368 RknRYVilpKDFEKG 382
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 696-936 1.49e-46

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 173.42  E-value: 1.49e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  696 KIPSVSWHDVGGLQDVKKEILETIQLPLEHPEL--LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELIN 773
Cdd:PTZ00361 176 KAPLESYADIGGLEQQIQEIKEAVELPLTHPELydDIGIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQ 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  774 MYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSgDSGGVMD--RVVSQLLAELDGLHSTQDVFVIGATNRPDL 851
Cdd:PTZ00361 256 KYLGDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDA-TSGGEKEiqRTMLELLNQLDGFDSRGDVKVIMATNRIES 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  852 LDPALLRPGRFD-KLVFvgASEDRASQLRVLSAITRKFKLEASVSL---MNVLDccppQLTGADLYSLCSDAMMTALK-R 926
Cdd:PTZ00361 335 LDPALIRPGRIDrKIEF--PNPDEKTKRRIFEIHTSKMTLAEDVDLeefIMAKD----ELSGADIKAICTEAGLLALReR 408

                        250
                 ....*....|....
gi 16923976  927 RVR----DLEEGLE 936
Cdd:PTZ00361 409 RMKvtqaDFRKAKE 422
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
742-942 7.59e-45

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 171.37  E-value: 7.59e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 742 GPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGdsGGVMD 821
Cdd:COG0465 182 GPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAGL--GGGHD 259

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 822 ---RVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGA--SEDRASQLRVLsaiTRKFKLEASVSL 896
Cdd:COG0465 260 ereQTLNQLLVEMDGFEGNEGVIVIAATNRPDVLDPALLRPGRFDRQVVVDLpdVKGREAILKVH---ARKKPLAPDVDL 336

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16923976 897 mNVLDCCPPQLTGADLYSLCSDAmmtAL------KRRV--RDLEE-------GLEPRSSAL 942
Cdd:COG0465 337 -EVIARRTPGFSGADLANLVNEA---ALlaarrnKKAVtmEDFEEaidrviaGPERKSRVI 393
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
741-957 8.00e-45

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 161.98  E-value: 8.00e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARaAAPCIIFFDELDSLAPSRGRSGDSGGvM 820
Cdd:COG1223  41 YGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYLGETARNLRKLFDFAR-RAPCVIFFDEFDAIAKDRGDQNDVGE-V 118

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 821 DRVVSQLLAELDGLHStqDVFVIGATNRPDLLDPALLRpgRFD-KLVFVgaSEDRASQLRVLSAITRKFKLEASVSLMNV 899
Cdd:COG1223 119 KRVVNALLQELDGLPS--GSVVIAATNHPELLDSALWR--RFDeVIEFP--LPDKEERKEILELNLKKFPLPFELDLKKL 192

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16923976 900 LDCCPPqLTGADLyslcSDAMMTALKRRVRDLEEgleprssalLLTMEDLLQAAARLQ 957
Cdd:COG1223 193 AKKLEG-LSGADI----EKVLKTALKKAILEDRE---------KVTKEDLEEALKQRK 236
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 704-864 1.23e-44

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 158.72  E-value: 1.23e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGL--LLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEE 781
Cdd:cd19518   1 DIGGMDSTLKELCELLIHPILPPEYFQHLGVEPPRgvLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 782 NVREVFARARAAAPCIIFFDELDSLAPSrgRSGDSGGVMDRVVSQLLAELDGL----HSTQDVFVIGATNRPDLLDPALL 857
Cdd:cd19518  81 KIRELFDQAISNAPCIVFIDEIDAITPK--RESAQREMERRIVSQLLTCMDELnnekTAGGPVLVIGATNRPDSLDPALR 158


                ....*..
gi 16923976 858 RPGRFDK 864
Cdd:cd19518 159 RAGRFDR 165
ftsH CHL00176
cell division protein; Validated
 700-927 3.32e-44

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 170.62  E-value: 3.32e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  700 VSWHDVGGLQDVKKEiLETIQLPLEHPELLSLGLRRSGL--LLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVG 777
Cdd:CHL00176 180 ITFRDIAGIEEAKEE-FEEVVSFLKKPERFTAVGAKIPKgvLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEMFVG 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  778 QSEENVREVFARARAAAPCIIFFDELDSLAPSRGrSGDSGGVMDR--VVSQLLAELDGLHSTQDVFVIGATNRPDLLDPA 855
Cdd:CHL00176 259 VGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRG-AGIGGGNDEReqTLNQLLTEMDGFKGNKGVIVIAATNRVDILDAA 337

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16923976  856 LLRPGRFDKLVFVGASeDRASQLRVLSAITRKFKLEASVSLMnVLDCCPPQLTGADLYSLCSDAMMTALKRR 927
Cdd:CHL00176 338 LLRPGRFDRQITVSLP-DREGRLDILKVHARNKKLSPDVSLE-LIARRTPGFSGADLANLLNEAAILTARRK 407
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
701-933 2.66e-43

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 167.90  E-value: 2.66e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  701 SWHDVGGLQDVKKEILETIQLpLEHPELLSLG--LRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQ 778
Cdd:PRK10733 150 TFADVAGCDEAKEEVAELVEY-LREPSRFQKLggKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGV 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  779 SEENVREVFARARAAAPCIIFFDELDSLAPSRGrSGDSGGVMDR--VVSQLLAELDGLHSTQDVFVIGATNRPDLLDPAL 856
Cdd:PRK10733 229 GASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRG-AGLGGGHDEReqTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPAL 307

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976  857 LRPGRFDKLVFVGASEDRASQlRVLSAITRKFKLEASVSlMNVLDCCPPQLTGADLYSLCSDAMMTALK--RRVRDLEE 933
Cdd:PRK10733 308 LRPGRFDRQVVVGLPDVRGRE-QILKVHMRRVPLAPDID-AAIIARGTPGFSGADLANLVNEAALFAARgnKRVVSMVE 384
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 705-868 6.70e-42

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 150.58  E-value: 6.70e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 705 VGGLQDVKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENV 783
Cdd:cd19509   1 IAGLDDAKEALKEAVILPSLRPDLfPGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 784 REVFARARAAAPCIIFFDELDSLAPSRGrSGDSGGVMdRVVSQLLAELDGL--HSTQDVFVIGATNRPDLLDPALLRpgR 861
Cdd:cd19509  81 RALFALARELQPSIIFIDEIDSLLSERG-SGEHEASR-RVKTEFLVQMDGVlnKPEDRVLVLGATNRPWELDEAFLR--R 156


                ....*..
gi 16923976 862 FDKLVFV 868
Cdd:cd19509 157 FEKRIYI 163
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
 704-864 1.72e-39

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 144.19  E-value: 1.72e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPE--LLSLGLRRSGLLLHGPPGTGKTLLAKAVATECS-----LTFLSVKGPELINMYV 776
Cdd:cd19517   1 DIGGLSHYINQLKEMVFFPLLYPEvfAKFKITPPRGVLFHGPPGTGKTLMARALAAECSkggqkVSFFMRKGADCLSKWV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 777 GQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSggVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPAL 856
Cdd:cd19517  81 GEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVRSSKQEQ--IHASIVSTLLALMDGLDNRGQVVVIGATNRPDALDPAL 158


                ....*...
gi 16923976 857 LRPGRFDK 864
Cdd:cd19517 159 RRPGRFDR 166
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
 741-863 2.89e-38

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 140.70  E-value: 2.89e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATecsltFLS------VKGPELINMYVGQSEENVREVFARARA--------AAPCIIFFDELDSL 806
Cdd:cd19504  41 YGPPGTGKTLMARQIGK-----MLNarepkiVNGPEILNKYVGESEANIRKLFADAEEeqrrlganSGLHIIIFDEIDAI 115

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 16923976 807 APSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFD 863
Cdd:cd19504 116 CKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRKDLIDEALLRPGRLE 172
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
 698-868 5.13e-36

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 134.22  E-value: 5.13e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 698 PSVSWHDVGGLQDVKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYV 776
Cdd:cd19521   2 PNVKWEDVAGLEGAKEALKEAVILPVKFPHLfTGNRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWM 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 777 GQSEENVREVFARARAAAPCIIFFDELDSLAPSRGrSGDSGGVMdRVVSQLLAELDGL-HSTQDVFVIGATNRPDLLDPA 855
Cdd:cd19521  82 GESEKLVKQLFAMARENKPSIIFIDEVDSLCGTRG-EGESEASR-RIKTELLVQMNGVgNDSQGVLVLGATNIPWQLDSA 159

                       170
                ....*....|...
gi 16923976 856 LLRpgRFDKLVFV 868
Cdd:cd19521 160 IRR--RFEKRIYI 170
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
 704-868 3.17e-33

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 126.25  E-value: 3.17e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPELLSLGLRR-SGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEEN 782
Cdd:cd19522   1 DIADLEEAKKLLEEAVVLPMWMPEFFKGIRRPwKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGESEKL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 783 VREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMdRVVSQLLAELDGLHSTQD-------VFVIGATNRPDLLDPA 855
Cdd:cd19522  81 VRLLFEMARFYAPTTIFIDEIDSICSRRGTSEEHEASR-RVKSELLVQMDGVGGASEnddpskmVMVLAATNFPWDIDEA 159

                       170
                ....*....|...
gi 16923976 856 LLRpgRFDKLVFV 868
Cdd:cd19522 160 LRR--RLEKRIYI 170
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
 698-868 4.88e-33

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 126.26  E-value: 4.88e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 698 PSVSWHDVGGLQDVKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYV 776
Cdd:cd19525  17 PPINWADIAGLEFAKKTIKEIVVWPMLRPDIfTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWV 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 777 GQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGvmDRVVSQLLAELDGLHSTQD--VFVIGATNRPDLLDP 854
Cdd:cd19525  97 GEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQRGEGEHESS--RRIKTEFLVQLDGATTSSEdrILVVGATNRPQEIDE 174

                       170
                ....*....|....
gi 16923976 855 ALLRpgRFDKLVFV 868
Cdd:cd19525 175 AARR--RLVKRLYI 186
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
 704-862 1.80e-32

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 123.69  E-value: 1.80e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLL---LHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSE 780
Cdd:cd19520   1 DIGGLDEVITELKELVILPLQRPELFDNSRLLQPPKgvlLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQ 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 781 ENVREVFARARAAAPCIIFFDELDSLAPSRgRSGDSgGVMDRVVSQLLAELDGLHSTQD--VFVIGATNRPDLLDPALLR 858
Cdd:cd19520  81 KLVAAVFSLASKLQPSIIFIDEIDSFLRQR-SSTDH-EATAMMKAEFMSLWDGLSTDGNcrVIVMGATNRPQDLDEAILR 158


                ....*.
gi 16923976 859 --PGRF 862
Cdd:cd19520 159 rmPKRF 164
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
 704-868 1.85e-32

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 123.81  E-value: 1.85e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEEN 782
Cdd:cd19524   1 DIAGQDLAKQALQEMVILPSLRPELfTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 783 VREVFARARAAAPCIIFFDELDSLAPSRgRSGDSGGVMdRVVSQLLAELDGLHSTQD--VFVIGATNRPDLLDPALLRpg 860
Cdd:cd19524  81 VRALFAVARELQPSIIFIDEVDSLLSER-SEGEHEASR-RLKTEFLIEFDGVQSNGDdrVLVMGATNRPQELDDAVLR-- 156


                ....*...
gi 16923976 861 RFDKLVFV 868
Cdd:cd19524 157 RFTKRVYV 164
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 741-869 1.55e-25

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 103.38  E-value: 1.55e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATEC---SLTFLSVKGPELINMYVGQSEEN---VREVFARARAAAPCIIFFDELDSLAPsrgrsg 814
Cdd:cd00009  25 YGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAELFGhflVRLLFELAEKAKPGVLFIDEIDSLSR------ 98

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 16923976 815 dsgGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVG 869
Cdd:cd00009  99 ---GAQNALLRVLETLNDLRIDRENVRVIGATNRPLLGDLDRALYDRLDIRIVIP 150
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
 742-868 2.15e-23

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 97.44  E-value: 2.15e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 742 GPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSgGVMD 821
Cdd:cd19507  38 GIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGESESRLRQMIQTAEAIAPCVLWIDEIEKGFSNADSKGDS-GTSS 116

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 16923976 822 RVVSQLLAELDglHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19507 117 RVLGTFLTWLQ--EKKKPVFVVATANNVQSLPPELLRKGRFDEIFFV 161
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 466-580 4.61e-21

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 90.81  E-value: 4.61e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGLGEDA 545
Cdd:cd19481  29 ILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFERARRLAPCILFIDEIDAIGRKRDSSGESG 108

                        90       100       110
                ....*....|....*....|....*....|....*
gi 16923976 546 RVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLP 580
Cdd:cd19481 109 ELRRVLNQLLTELDGVNSRSKVLVIAATNRPDLLD 143
ycf46 CHL00195
Ycf46; Provisional
 742-869 1.09e-18

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 90.46  E-value: 1.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  742 GPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSgGVMD 821
Cdd:CHL00195 266 GIQGTGKSLTAKAIANDWQLPLLRLDVGKLFGGIVGESESRMRQMIRIAEALSPCILWIDEIDKAFSNSESKGDS-GTTN 344

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 16923976  822 RVVSQLLAELDglHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVG 869
Cdd:CHL00195 345 RVLATFITWLS--EKKSPVFVVATANNIDLLPLEILRKGRFDEIFFLD 390
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
 704-868 7.18e-18

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 81.85  E-value: 7.18e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 704 DVGGLQDVKKEILETIQLPLEHPEL-LSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEEN 782
Cdd:cd19523   1 DIAGLGALKAAIKEEVLWPLLRPDAfSGLLRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEGEKI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 783 VREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGvmdRVVSQLLAELDG-LHSTQD-VFVIGATNRPDLLDPALLRpg 860
Cdd:cd19523  81 LQASFLAARCRQPSVLFISDLDALLSSQDDEASPVG---RLQVELLAQLDGvLGSGEDgVLVVCTTSKPEEIDESLRR-- 155


                ....*...
gi 16923976 861 RFDKLVFV 868
Cdd:cd19523 156 YFSKRLLV 163
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 741-872 3.85e-17

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 79.34  E-value: 3.85e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976    741 HGPPGTGKTLLAKAVATECSLTFLSVK-----------------GPELINMYVGQSEENVREVFARARAAAPCIIFFDEL 803
Cdd:smart00382   8 VGPPGSGKTTLARALARELGPPGGGVIyidgedileevldqlllIIVGGKKASGSGELRLRLALALARKLKPDVLILDEI 87

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976    804 DSLApsrgrsgDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPgRFDKLVFVGASE 872
Cdd:smart00382  88 TSLL-------DAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRR-RFDRRIVLLLIL 148
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 466-595 1.74e-16

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 76.86  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVV---------LLLtaldllgR 536
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVifideidalAGS-------R 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 16923976   537 DRDGLGEDARVVATLRHLLldEDPLSRCPPLMVVATTSRVQDLPTDVRTAFPHELEVPV 595
Cdd:pfam00004  74 GSGGDSESRRVVNQLLTEL--DGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 284-683 1.93e-16

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 82.65  E-value: 1.93e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 284 DPLEVGELRIQRYLEDSTAAEDKGSCSLLPGPPFARELHIEVLPSPHCGVNGKYDHVLYQHFHTPRVVQEGDVLCVSTAG 363
Cdd:COG0464   1 LAELLALAVALALALLLLDDAALRLLLLLLLALAAALLLLLLLLLLLLLALLLVELLLLLLSGALAALLLLALLLLALLA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 364 QVEILEGSLERLPRWREVFFKVKKTVGEAPDGPASAFLADTTHTSLYLAGTTLSRVPPLPSG---------RSPPWDSLS 434
Cdd:COG0464  81 LLAALLSALELLLLGELLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGgleeellelREAILDDLG 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 435 -PPGLEALVNELCAVLKPH---LQPGGtlLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLcadSSRTV--- 507
Cdd:COG0464 161 gLEEVKEELRELVALPLKRpelREEYG--LPPPRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDL---VSKYVget 235

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 508 ETKLQTTFSRARRCRPVVllltaldllGRDRDGLGEDA--RVVATlrhLL--LDEDPlsrcPPLMVVATTSRVQDLPTDV 583
Cdd:COG0464 236 EKNLREVFDKARGLAPCVlfideadalAGKRGEVGDGVgrRVVNT---LLteMEELR----SDVVVIAATNRPDLLDPAL 308

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 584 RTAFPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLSQLARRCAGFVVGDLyallthasRAACtrIKAAGLAMSEEDEg 663
Cdd:COG0464 309 LRRFDEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEGLSGADI--------RNVV--RRAALQALRLGRE- 377

                       410       420
                ....*....|....*....|
gi 16923976 664 elcaagfPLLAEDFGQALDQ 683
Cdd:COG0464 378 -------PVTTEDLLEALER 390
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 437-684 2.15e-14

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 75.43  E-value: 2.15e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 437 GLEALVNELC-AVLKPHLQPG-----GTLLTGTscVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLcadSSRTV--- 507
Cdd:COG1222  82 GLDEQIEEIReAVELPLKNPElfrkyGIEPPKG--VLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSEL---VSKYIgeg 156

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 508 ETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGL---GEDARVVATlrhlLLDE-DPLSRCPPLMVVATTSRVQDL-PTD 582
Cdd:COG1222 157 ARNVREVFELAREKAPSIIFIDEIDAIAARRTDDgtsGEVQRTVNQ----LLAElDGFESRGDVLIIAATNRPDLLdPAL 232

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 583 VRTA-FPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLSQLARRCAGFVVGDLyallthasRAACTRikAAGLAMSEED 661
Cdd:COG1222 233 LRPGrFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKLAKLTEGFSGADL--------KAIVTE--AGMFAIREGR 302

                       250       260
                ....*....|....*....|...
gi 16923976 662 EGelcaagfpLLAEDFGQALDQL 684
Cdd:COG1222 303 DT--------VTMEDLEKAIEKV 317
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
466-686 3.69e-14

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 73.38  E-value: 3.69e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLcaDSSRTVET--KLQTTFSRARRcRPVVLLLTALDLLGRDRDGL-- 541
Cdd:COG1223  38 ILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSL--IGSYLGETarNLRKLFDFARR-APCVIFFDEFDAIAKDRGDQnd 114

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 542 -GEDARVVATLRhLLLDEDPlsrcPPLMVVATTSRVQDLPTDVRTAFPHELEVPVLSESQRLSVLQALTAHLPLGQEVNL 620
Cdd:COG1223 115 vGEVKRVVNALL-QELDGLP----SGSVVIAATNHPELLDSALWRRFDEVIEFPLPDKEERKEILELNLKKFPLPFELDL 189

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16923976 621 SQLARRCAGFVVGDLYALLTHAsraactrIKAAGLAMSEEdegelcaagfpLLAEDFGQALDQLQT 686
Cdd:COG1223 190 KKLAKKLEGLSGADIEKVLKTA-------LKKAILEDREK-----------VTKEDLEEALKQRKE 237
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 741-868 9.63e-13

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 66.61  E-value: 9.63e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATECSLTFLsvkgpeLINMY-VGQSEENVREVFARARAAApcIIFFDELDSLAPSR---GRSGDS 816
Cdd:cd19510  29 YGPPGTGKSSFIAALAGELDYDIC------DLNLSeVVLTDDRLNHLLNTAPKQS--IILLEDIDAAFESRehnKKNPSA 100

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 16923976 817 GGVMDRV-VSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFV 868
Cdd:cd19510 101 YGGLSRVtFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGRVDMKIYM 153
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
 741-856 3.17e-09

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 57.84  E-value: 3.17e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATECSL---------TFLSVKGPELINMYVGQSEENVREVFARARAAAP---CIIF--FDELDSL 806
Cdd:cd19508  58 HGPPGTGKTSLCKALAQKLSIrlssryrygQLIEINSHSLFSKWFSESGKLVTKMFQKIQELIDdkdALVFvlIDEVESL 137

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 16923976 807 APSRG--RSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPAL 856
Cdd:cd19508 138 AAARSasSSGTEPSDAIRVVNAVLTQIDRIKRYHNNVILLTSNLLEKIDVAF 189
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 437-591 5.16e-08

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 53.56  E-value: 5.16e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 437 GLEALVNELCA-VLKPHLQPGGTLLTGT---SCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQ 512
Cdd:cd19518   4 GMDSTLKELCElLIHPILPPEYFQHLGVeppRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEEKIR 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 513 TTFSRARRCRPVVLLLTALDLLGRDRDGLGEDA--RVVAtlrHLLLDEDPLSRCP----PLMVVATTSRVQDLPTDVRTA 586
Cdd:cd19518  84 ELFDQAISNAPCIVFIDEIDAITPKRESAQREMerRIVS---QLLTCMDELNNEKtaggPVLVIGATNRPDSLDPALRRA 160


                ....*..
gi 16923976 587 --FPHEL 591
Cdd:cd19518 161 grFDREI 167
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
 742-866 1.46e-07

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 51.99  E-value: 1.46e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 742 GPPGTGKTLLAKAVATECSLTFLSV--------------KGPELINMYVGQSEENVREVFARARAAAPCIIFFD---ELD 804
Cdd:cd19505  19 GSIETGRSYLIKSLAANSYVPLIRIslnkllynkpdfgnDDWIDGMLILKESLHRLNLQFELAKAMSPCIIWIPnihELN 98

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16923976 805 SLAPSRGRSGDSGGVMDRVVSqLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLV 866
Cdd:cd19505  99 VNRSTQNLEEDPKLLLGLLLN-YLSRDFEKSSTRNILVIASTHIPQKVDPALIAPNRLDTCI 159
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
456-643 2.84e-07

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 54.66  E-value: 2.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  456 GGTLLTGtscVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLG 535
Cdd:PRK10733 181 GGKIPKG---VLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVG 257

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  536 RDRD---GLGEDARvVATLRHLLLDEDPLSRCPPLMVVATTSRVQDL-PTDVRTA-FPHELEVPVLSESQRLSVLQALTA 610
Cdd:PRK10733 258 RQRGaglGGGHDER-EQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLdPALLRPGrFDRQVVVGLPDVRGREQILKVHMR 336

                        170       180       190
                 ....*....|....*....|....*....|...
gi 16923976  611 HLPLGQEVNLSQLARRCAGFVVGDLYALLTHAS 643
Cdd:PRK10733 337 RVPLAPDIDAAIIARGTPGFSGADLANLVNEAA 369
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 466-579 3.59e-07

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 51.14  E-value: 3.59e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVL--LLTALDLLGRDRDGLGE 543
Cdd:cd19503  37 VLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEKNLREIFEEARSHAPSIIfiDEIDALAPKREEDQREV 116

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 16923976 544 DARVVATLRHLLldeDPLSRCPPLMVVATTSRVQDL 579
Cdd:cd19503 117 ERRVVAQLLTLM---DGMSSRGKVVVIAATNRPDAI 149
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
 742-851 5.78e-07

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 53.31  E-value: 5.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   742 GPPGTGKTLLAKAVATE-CSLTFLS------VKGPELINMYVGQSEENVREVFARARAAapcIIFFDELDSLAPSRGRSG 814
Cdd:TIGR03922 319 GPPGTGKTTIARVVAKIyCGLGVLRkplvreVSRADLIGQYIGESEAKTNEIIDSALGG---VLFLDEAYTLVETGYGQK 395

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 16923976   815 DSGGVMdrVVSQLLAELDglHSTQDVFVIGATNRPDL 851
Cdd:TIGR03922 396 DPFGLE--AIDTLLARME--NDRDRLVVIGAGYRKDL 428
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 741-866 1.27e-05

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 45.98  E-value: 1.27e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 741 HGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYvGQSEENVREVFARARAAAP-CIIFFDELDSLAPSRGRSGDSGGV 819
Cdd:cd19512  28 YGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMG-REGVTAIHKVFDWANTSRRgLLLFVDEADAFLRKRSTEKISEDL 106

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 16923976 820 mdRVVSQLLAELDGLHSTQDVFVIgATNRPDLLDPALlrPGRFDKLV 866
Cdd:cd19512 107 --RAALNAFLYRTGEQSNKFMLVL-ASNQPEQFDWAI--NDRIDEMV 148
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
 437-593 1.30e-05

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 46.65  E-value: 1.30e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 437 GLEALVNEL-----CAVLKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLC----ADSSRTV 507
Cdd:cd19520   4 GLDEVITELkelviLPLQRPELFDNSRLLQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTdkwyGESQKLV 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 508 EtklqTTFSRARRCRPVVLLLTALDLLGRDRDglGEDARVVATLRHLL------LDEDPLSRcppLMVVATTSRVQDLPT 581
Cdd:cd19520  84 A----AVFSLASKLQPSIIFIDEIDSFLRQRS--STDHEATAMMKAEFmslwdgLSTDGNCR---VIVMGATNRPQDLDE 154

                       170
                ....*....|..
gi 16923976 582 DVRTAFPHELEV 593
Cdd:cd19520 155 AILRRMPKRFHI 166
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
 741-802 1.11e-04

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 45.82  E-value: 1.11e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16923976 741 HGPPGTGKTLLAKAVATECSLTF--LS-----VKgpelinmyvgqseeNVREVFARARAAA----PCIIFFDE 802
Cdd:COG2256  55 WGPPGTGKTTLARLIANATDAEFvaLSavtsgVK--------------DIREVIEEARERRaygrRTILFVDE 113
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 447-575 3.58e-04

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 42.09  E-value: 3.58e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 447 AVLKPHLQPGGTLLTGTSC---VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRP 523
Cdd:cd19530  11 SILRPIKRPDIYKALGIDLptgVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQVFQRARASAP 90

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 16923976 524 VVL--LLTALDLLGRDRDGLGEDARVVATlrhLLLDEDPLSRCPPLMVVATTSR 575
Cdd:cd19530  91 CVIffDEVDALVPKRGDGGSWASERVVNQ---LLTEMDGLEERSNVFVIAATNR 141
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 742-802 4.93e-04

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 43.53  E-value: 4.93e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16923976  742 GPPGTGKTLLAKAVATECSLTFLSVKGpelinmyVGQSEENVREVFARARAAA----PCIIFFDE 802
Cdd:PRK13342  43 GPPGTGKTTLARIIAGATDAPFEALSA-------VTSGVKDLREVIEEARQRRsagrRTILFIDE 100
ycf2 CHL00206
Ycf2; Provisional
 836-937 1.03e-03

Ycf2; Provisional


Pssm-ID: 214396 [Multi-domain]  Cd Length: 2281  Bit Score: 43.36  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   836 STQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGAS--EDRASQLRVLSAiTRKFKLEASVSLMNVLDCCPPQLTGADLY 913
Cdd:CHL00206 1769 STRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLliPQQRKHFFTLSY-TRGFHLEKKMFHTNGFGSITMGSNARDLV 1847

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 16923976   914 SL----------------CSDAMMTALKRRVRDLEEGLEP 937
Cdd:CHL00206 1848 ALtnealsisitqkksiiDTNTIRSALHRQTWDLRSQVRS 1887
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
 448-593 1.05e-03

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 41.13  E-value: 1.05e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 448 VLKPHLQPggTLLTGTSC----VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRP 523
Cdd:cd19525  38 VVWPMLRP--DIFTGLRGppkgILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFSVARCKQP 115

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16923976 524 VVLLLTALDLLGRDR-DGLGEDARVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLPTDVRTAFPHELEV 593
Cdd:cd19525 116 AVIFIDEIDSLLSQRgEGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYI 186
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 466-575 1.13e-03

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 40.49  E-value: 1.13e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVL--LLTALDLLGRDRDGLGE 543
Cdd:cd19526  30 ILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFSRAQSAKPCILffDEFDSIAPKRGHDSTGV 109

                        90       100       110
                ....*....|....*....|....*....|..
gi 16923976 544 DARVVatlRHLLLDEDPLSRCPPLMVVATTSR 575
Cdd:cd19526 110 TDRVV---NQLLTQLDGVEGLDGVYVLAATSR 138
ftsH CHL00176
cell division protein; Validated
 466-662 1.36e-03

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 42.34  E-value: 1.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  466 VLLQGPPGSGKTTAVTAACSRLGlhllkVPCSSLcaDSSRTVE-------TKLQTTFSRARRCRPVVLLLTALDLLGRDR 538
Cdd:CHL00176 219 VLLVGPPGTGKTLLAKAIAGEAE-----VPFFSI--SGSEFVEmfvgvgaARVRDLFKKAKENSPCIVFIDEIDAVGRQR 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976  539 D---GLGEDARVvATLRHLLLDEDPLSRCPPLMVVATTSRVqdlptDVRTA-------FPHELEVPVLSESQRLSVLQAL 608
Cdd:CHL00176 292 GagiGGGNDERE-QTLNQLLTEMDGFKGNKGVIVIAATNRV-----DILDAallrpgrFDRQITVSLPDREGRLDILKVH 365

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 16923976  609 TAHLPLGQEVNLSQLARRCAGFVVGDLYALLTHASRAACTRIKAAgLAMSEEDE 662
Cdd:CHL00176 366 ARNKKLSPDVSLELIARRTPGFSGADLANLLNEAAILTARRKKAT-ITMKEIDT 418
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 466-575 1.90e-03

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 39.96  E-value: 1.90e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 466 VLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSL----CADSSRTVetklQTTFSRARRCRP-VVLLLTALDLLGR--DR 538
Cdd:cd19511  30 VLLYGPPGCGKTLLAKALASEAGLNFISVKGPELfskyVGESERAV----REIFQKARQAAPcIIFFDEIDSLAPRrgQS 105

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 16923976 539 DGLGEDARVVATlrhLLLDEDPLSRCPPLMVVATTSR 575
Cdd:cd19511 106 DSSGVTDRVVSQ---LLTELDGIESLKGVVVIAATNR 139
Vps4_C pfam09336
Vps4 C terminal oligomerization domain; This domain is found at the C terminal of ATPase ...
 923-975 3.54e-03

Vps4 C terminal oligomerization domain; This domain is found at the C terminal of ATPase proteins involved in vacuolar sorting. It forms an alpha helix structure and is required for oligomerization.


Pssm-ID: 462762 [Multi-domain]  Cd Length: 61  Bit Score: 36.71  E-value: 3.54e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 16923976   923 ALKRRVRDLEEG--LEPRssallLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 975
Cdd:pfam09336  11 AIEMTWMDIPSDklLEPP-----VTMKDFLKALKSSRPTVSKEDLEKYEEFTKEF 60
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 742-862 3.87e-03

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 38.43  E-value: 3.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976   742 GPPGTGKTLLAKAVAtecslTFLSVKGPELINMYVGQSEENV---REVFARA---------RAAA-PCIIFFDELDSLAP 808
Cdd:pfam07728   6 GPPGTGKTELAERLA-----AALSNRPVFYVQLTRDTTEEDLfgrRNIDPGGaswvdgplvRAAReGEIAVLDEINRANP 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16923976   809 SrgrsgdsggVMDRVVSQL------LAELDGL--HSTQDVFVIGATNRPDL----LDPALLRpgRF 862
Cdd:pfam07728  81 D---------VLNSLLSLLderrllLPDGGELvkAAPDGFRLIATMNPLDRglneLSPALRS--RF 135
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 448-593 5.55e-03

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 38.87  E-value: 5.55e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16923976 448 VLKPHLQPGgtLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLL 527
Cdd:cd19509  19 SLRPDLFPG--LRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIVRALFALARELQPSIIF 96

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16923976 528 LTALDLLGRDRDglGEDARVVATLRHLLLDE------DPLSRcppLMVVATTSRVQDLPTDVRTAFPHELEV 593
Cdd:cd19509  97 IDEIDSLLSERG--SGEHEASRRVKTEFLVQmdgvlnKPEDR---VLVLGATNRPWELDEAFLRRFEKRIYI 163
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 464-499 6.78e-03

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 38.28  E-value: 6.78e-03
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 16923976 464 SCVLLQGPPGSGKTTAVTA---ACSRLGLHLLKVPCSSL 499
Cdd:cd00009  20 KNLLLYGPPGTGKTTLARAianELFRPGAPFLYLNASDL 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH