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Conserved domains on  [gi|47578105|ref|NP_597677|]
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nipped-B-like protein isoform A [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SCC2 cd23958
Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid ...
1263-2473 0e+00

Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid cohesion protein 2 (Scc2) and its homolog (Scc2 homolog, also called Nipped-B-like protein or NIPBL). Scc2/NIPBL and Scc4 form a complex that is responsible for loading the cohesin protein onto sister chromatids during mitosis and meiosis. Cohesin is a ring-shaped protein complex that encircles the sister chromatids and helps to hold them together until they are ready to be separated during cell division. In addition to its role in chromosome segregation, cohesin also plays important roles in other cellular processes such as transcription, chromosome condensation, and DNA repair.


:

Pssm-ID: 467937 [Multi-domain]  Cd Length: 1197  Bit Score: 1442.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1263 VKVLNILEKNIQDGSKLStLLNHNNDTEEEERLWRDLIMERVTKSADACLTtinIMTSPNMPKAVYIEDVIERVIQYTKF 1342
Cdd:cd23958    3 VRLLTILERNIRDGESLD-LDLDESQEDDEERLWLLERIDRALEAADASLT---ILTSPGLPKQLYSEDLIERVVDFLKF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1343 HLQNTLYPQYDPVYRLDPHGGGLlssKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPF 1422
Cdd:cd23958   79 QLENTIYPAYDPVYRSDSSAKAG---KKKRAKASSKKKKSVSTLLNKLCELLSLLAELLSLQSLTDSVILQLVYLAISPF 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1423 FVE----NVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDmdgepmYIQMVTALVLQLI 1498
Cdd:cd23958  156 FVEnavsNVDELQLSALKLLTSIFSRYPDQRQFIIEEILSSLAKLPSSKRNLRQFRLNDGK------SIQMVTALLLQLV 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1499 QCVVHLPSSEKDSN-----AEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSK--QGEEDYRPLFENFVQDLLS 1571
Cdd:cd23958  230 QSSVKLPNLEKESSrdkslEEDSDELLEDEESALAKSYESAVRIASYFLSFLLQKCTKKkkEKDTDYRPLFENFVQDLLT 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1572 TVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTskmdqgsierilkqvsggedeiQQL 1651
Cdd:cd23958  310 VLNLPEWPAAELLLSLLGRLLVSIFSNKKTDANARVMALDLLGLIAARLRKDALA----------------------EEL 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1652 QKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKsqkdeessegthhAKEIETTGQIMHRAENRKKFLRSIi 1731
Cdd:cd23958  368 QKALLDYLAENSSSDPSLESARGFYLAQWLRDLSNELEKAEK-------------AAEEEDTILKLELSELRKKFLDSK- 433
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1732 kttpsqFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLD 1811
Cdd:cd23958  434 ------ILSKEEEASPLSREDAKLLYRALASQRPLSQSFDPILKQLLSSLDEPAVTLRTKALKALSLVVEADPSILGDPD 507
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1812 MQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVK 1891
Cdd:cd23958  508 VQRAVEGRLLDSSASVREAAVELVGKYISSRPDLAEQYYEMIAERILDTGVSVRKRVIKILRDIYLRTPDFEIKVDICVR 587
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1892 MIRRVND-EEGIKKLVNETFQKLWFTPTPHN-----DKEAMTRKILNITDVVAACRdTGYDWFEQLLQNLLKSEEDSSYK 1965
Cdd:cd23958  588 LLRRINDeEESIKDLARKTFQELWFTPFPESsspaqDKESLAERVLLIVDVVAACR-KGLDLLEQLLKRLLKSKEDKEDK 666
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1966 PVKKACTQLVDNLVEHILKYEESLADSdnkgvNSGRLVACITTLFLFSKIRP-QLMVKHAMTMQPYLTTKCSTQNDFMVI 2044
Cdd:cd23958  667 SVRKACKQLVDCLVELILELEEDDDES-----SESDLVACLSTLHLFAKADPkLLLVEHAETLQPYLKSKCSTREDQQVL 741
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2045 CNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQH 2124
Cdd:cd23958  742 RYVLRILRSVLPLLSHPSESFLEELEEDLLKLLLKHSVTVLQEAIACLCAVVNKLTKNYERLRKALQSCLKLLRKYKRQA 821
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2125 QEDPNNTsllTNKPALLRSLFTVGALCRHFDFDLEDFKGN-----SKVNIKDKVLELLMYFTKHS-DEEVQTKAIIGLGF 2198
Cdd:cd23958  822 NLDPSSL---KEDPKLLRLLYILGLLARYCDFDSERDDFEkaplkTKESVKELVFDLLLFFTKPPiDEDVRKKALQALGF 898
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2199 AFIQHPSLMFEQEVKNLYNNILSDknSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQ-----EDLKEMGDVSSG 2273
Cdd:cd23958  899 LCIAHPKLFLSPEVLKLLDEILAS--GSLKLKLQVLRNLQEFLQAEEKRMEAADAEWKKNSKAadvkvLDGKEMGDADSG 976
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2274 MSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFI 2353
Cdd:cd23958  977 VASSIMQRYLKDILELCLSSDSQVRLAALKVLELILRQGLVHPIQCVPTLIALETDPNPAIRKLALRLLKELHEKYESLV 1056
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2354 HMKAVAGMKMSYQVQQAINTclKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDD------TAKTDVTM 2427
Cdd:cd23958 1057 ESKYLEGVRLAFQYQKRLAG--DTRGRGFRTDSPPTALLGRLYSLLRGNRKSRRKFLKSLLKLFDFdlkkssDSPSDLDF 1134
                       1210      1220      1230      1240
                 ....*....|....*....|....*....|....*....|....*..
gi 47578105 2428 LLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSF-KESMV 2473
Cdd:cd23958 1135 LLFLAENLAFLPYQTQDEPLFVIHTIDRILSVTGSSLLQAIaKASQA 1181
PspC_subgroup_2 super family cl41463
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
597-832 2.03e-15

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


The actual alignment was detected with superfamily member NF033839:

Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 82.51  E-value: 2.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   597 PETPKKKSDPELS--KSEMKQS-ESRLAESKPN-ENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNEstiVEPK 672
Cdd:NF033839  281 QDTPKEPGNKKPSapKPGMQPSpQPEKKEVKPEpETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPE---VKPQ 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   673 qnenrLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNE 752
Cdd:NF033839  358 -----PEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVK 432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   753 GRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPR------LKSERAEALKQRPDGR--SVSESLRRDhdnKQKS 824
Cdd:NF033839  433 PQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKpevkpqPEKPKPDNSKPQADDKkpSTPNNLSKD---KQPS 509

                  ....*...
gi 47578105   825 DDRGESER 832
Cdd:NF033839  510 NQASTNEK 517
PTZ00121 super family cl31754
MAEBL; Provisional
476-1092 3.81e-12

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   476 EIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQA 555
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   556 SITQ-DSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENhpetPKKKSDpELSKSEMKQSESRLAESKPNENRlvetK 634
Cdd:PTZ00121 1362 AEEKaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKAD-ELKKAAAAKKKADEAKKKAEEKK----K 1432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   635 SSENKLETKVETQTEELKQnesRTTECKQNEStiVEPKQNENRLSDtKPNDNKQNNGRSETTKSRPETPKQKGES--RPE 712
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADEAKK---KAEEAKKAEE--AKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKADEakKAA 1506
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   713 TPKQKSDghpETPKQKgdgrpETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDS---GKPSTEKKPEVSKHKQDTKSD 789
Cdd:PTZ00121 1507 EAKKKAD---EAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAeelKKAEEKKKAEEAKKAEEDKNM 1578
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   790 SPRlkseRAEALKQRPDGRSV-------------SESLRRDHDNKQKSDD--RGESERHRGDQSR------VRRPETLRS 848
Cdd:PTZ00121 1579 ALR----KAEEAKKAEEARIEevmklyeeekkmkAEEAKKAEEAKIKAEElkKAEEEKKKVEQLKkkeaeeKKKAEELKK 1654
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   849 SSRN-------------EHGIKSDSSKTDKLERKHRHESGDSRE---------RPSSGEQKSRPDSPRvKQGDSNKSRSD 906
Cdd:PTZ00121 1655 AEEEnkikaaeeakkaeEDKKKAEEAKKAEEDEKKAAEALKKEAeeakkaeelKKKEAEEKKKAEELK-KAEEENKIKAE 1733
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   907 KLGFKSPTSK----DDKRTEGNKSKVDTNKAHPDNKAEfpsyllggRSGALKNFVIPKIKRDKDgnvtqETKKMEMKGEP 982
Cdd:PTZ00121 1734 EAKKEAEEDKkkaeEAKKDEEEKKKIAHLKKEEEKKAE--------EIRKEKEAVIEEELDEED-----EKRRMEVDKKI 1800
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   983 KDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIK-------NKPSKSNKGSIDQSVLKELPPEL 1055
Cdd:PTZ00121 1801 KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEkhkfnknNENGEDGNKEADFNKEKDLKEDD 1880
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 47578105  1056 LAEIESTMplcERVKMNK----RKRSTVNEKPKYAEISSDE 1092
Cdd:PTZ00121 1881 EEEIEEAD---EIEKIDKddieREIPNNNMAGKNNDIIDDK 1918
 
Name Accession Description Interval E-value
SCC2 cd23958
Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid ...
1263-2473 0e+00

Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid cohesion protein 2 (Scc2) and its homolog (Scc2 homolog, also called Nipped-B-like protein or NIPBL). Scc2/NIPBL and Scc4 form a complex that is responsible for loading the cohesin protein onto sister chromatids during mitosis and meiosis. Cohesin is a ring-shaped protein complex that encircles the sister chromatids and helps to hold them together until they are ready to be separated during cell division. In addition to its role in chromosome segregation, cohesin also plays important roles in other cellular processes such as transcription, chromosome condensation, and DNA repair.


Pssm-ID: 467937 [Multi-domain]  Cd Length: 1197  Bit Score: 1442.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1263 VKVLNILEKNIQDGSKLStLLNHNNDTEEEERLWRDLIMERVTKSADACLTtinIMTSPNMPKAVYIEDVIERVIQYTKF 1342
Cdd:cd23958    3 VRLLTILERNIRDGESLD-LDLDESQEDDEERLWLLERIDRALEAADASLT---ILTSPGLPKQLYSEDLIERVVDFLKF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1343 HLQNTLYPQYDPVYRLDPHGGGLlssKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPF 1422
Cdd:cd23958   79 QLENTIYPAYDPVYRSDSSAKAG---KKKRAKASSKKKKSVSTLLNKLCELLSLLAELLSLQSLTDSVILQLVYLAISPF 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1423 FVE----NVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDmdgepmYIQMVTALVLQLI 1498
Cdd:cd23958  156 FVEnavsNVDELQLSALKLLTSIFSRYPDQRQFIIEEILSSLAKLPSSKRNLRQFRLNDGK------SIQMVTALLLQLV 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1499 QCVVHLPSSEKDSN-----AEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSK--QGEEDYRPLFENFVQDLLS 1571
Cdd:cd23958  230 QSSVKLPNLEKESSrdkslEEDSDELLEDEESALAKSYESAVRIASYFLSFLLQKCTKKkkEKDTDYRPLFENFVQDLLT 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1572 TVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTskmdqgsierilkqvsggedeiQQL 1651
Cdd:cd23958  310 VLNLPEWPAAELLLSLLGRLLVSIFSNKKTDANARVMALDLLGLIAARLRKDALA----------------------EEL 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1652 QKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKsqkdeessegthhAKEIETTGQIMHRAENRKKFLRSIi 1731
Cdd:cd23958  368 QKALLDYLAENSSSDPSLESARGFYLAQWLRDLSNELEKAEK-------------AAEEEDTILKLELSELRKKFLDSK- 433
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1732 kttpsqFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLD 1811
Cdd:cd23958  434 ------ILSKEEEASPLSREDAKLLYRALASQRPLSQSFDPILKQLLSSLDEPAVTLRTKALKALSLVVEADPSILGDPD 507
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1812 MQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVK 1891
Cdd:cd23958  508 VQRAVEGRLLDSSASVREAAVELVGKYISSRPDLAEQYYEMIAERILDTGVSVRKRVIKILRDIYLRTPDFEIKVDICVR 587
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1892 MIRRVND-EEGIKKLVNETFQKLWFTPTPHN-----DKEAMTRKILNITDVVAACRdTGYDWFEQLLQNLLKSEEDSSYK 1965
Cdd:cd23958  588 LLRRINDeEESIKDLARKTFQELWFTPFPESsspaqDKESLAERVLLIVDVVAACR-KGLDLLEQLLKRLLKSKEDKEDK 666
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1966 PVKKACTQLVDNLVEHILKYEESLADSdnkgvNSGRLVACITTLFLFSKIRP-QLMVKHAMTMQPYLTTKCSTQNDFMVI 2044
Cdd:cd23958  667 SVRKACKQLVDCLVELILELEEDDDES-----SESDLVACLSTLHLFAKADPkLLLVEHAETLQPYLKSKCSTREDQQVL 741
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2045 CNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQH 2124
Cdd:cd23958  742 RYVLRILRSVLPLLSHPSESFLEELEEDLLKLLLKHSVTVLQEAIACLCAVVNKLTKNYERLRKALQSCLKLLRKYKRQA 821
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2125 QEDPNNTsllTNKPALLRSLFTVGALCRHFDFDLEDFKGN-----SKVNIKDKVLELLMYFTKHS-DEEVQTKAIIGLGF 2198
Cdd:cd23958  822 NLDPSSL---KEDPKLLRLLYILGLLARYCDFDSERDDFEkaplkTKESVKELVFDLLLFFTKPPiDEDVRKKALQALGF 898
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2199 AFIQHPSLMFEQEVKNLYNNILSDknSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQ-----EDLKEMGDVSSG 2273
Cdd:cd23958  899 LCIAHPKLFLSPEVLKLLDEILAS--GSLKLKLQVLRNLQEFLQAEEKRMEAADAEWKKNSKAadvkvLDGKEMGDADSG 976
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2274 MSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFI 2353
Cdd:cd23958  977 VASSIMQRYLKDILELCLSSDSQVRLAALKVLELILRQGLVHPIQCVPTLIALETDPNPAIRKLALRLLKELHEKYESLV 1056
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2354 HMKAVAGMKMSYQVQQAINTclKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDD------TAKTDVTM 2427
Cdd:cd23958 1057 ESKYLEGVRLAFQYQKRLAG--DTRGRGFRTDSPPTALLGRLYSLLRGNRKSRRKFLKSLLKLFDFdlkkssDSPSDLDF 1134
                       1210      1220      1230      1240
                 ....*....|....*....|....*....|....*....|....*..
gi 47578105 2428 LLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSF-KESMV 2473
Cdd:cd23958 1135 LLFLAENLAFLPYQTQDEPLFVIHTIDRILSVTGSSLLQAIaKASQA 1181
Nipped-B_C pfam12830
Sister chromatid cohesion C-terminus; This domain lies towards the C-terminus of nipped-B or ...
2275-2456 7.31e-70

Sister chromatid cohesion C-terminus; This domain lies towards the C-terminus of nipped-B or sister chromatid cohesion proteins.


Pssm-ID: 463722  Cd Length: 180  Bit Score: 232.81  E-value: 7.31e-70
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   2275 SSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIH 2354
Cdd:pfam12830    1 CSALVQRYLKHILEICLSSDDQVRLLALEVLALILRQGLVHPKECIPTLIALETSPNPYIRKLAFELHKELHEKHESLLE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   2355 MKAVAGMKMSYQVQQAINTClkdpvrgfRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDD------TAKTDVTML 2428
Cdd:pfam12830   81 SRYMEGIRLAFEYQRRVLSG--------ATLEPPTSFLSLLYSLLRSNKKSRKKFLKSLVKLFFDldlsseSSPSDLDFL 152
                          170       180
                   ....*....|....*....|....*...
gi 47578105   2429 LYIADNLACFPYQTQEEPLFIMHHIDIT 2456
Cdd:pfam12830  153 RFLAENLAFLPYQTQDEVLFLIHHIDRI 180
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
597-832 2.03e-15

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 82.51  E-value: 2.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   597 PETPKKKSDPELS--KSEMKQS-ESRLAESKPN-ENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNEstiVEPK 672
Cdd:NF033839  281 QDTPKEPGNKKPSapKPGMQPSpQPEKKEVKPEpETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPE---VKPQ 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   673 qnenrLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNE 752
Cdd:NF033839  358 -----PEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVK 432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   753 GRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPR------LKSERAEALKQRPDGR--SVSESLRRDhdnKQKS 824
Cdd:NF033839  433 PQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKpevkpqPEKPKPDNSKPQADDKkpSTPNNLSKD---KQPS 509

                  ....*...
gi 47578105   825 DDRGESER 832
Cdd:NF033839  510 NQASTNEK 517
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
590-790 2.42e-13

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 75.58  E-value: 2.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   590 KSTPENHPETPKKKSDPELSKsEMKQSESRLAESKPNENRLVETKSSENKLETkvETQTEELK-QNESRTTECKQNESTi 668
Cdd:NF033839  329 KPEVKPQPEKPKPEVKPQLET-PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQP--ETPKPEVKpQPEKPKPEVKPQPEK- 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   669 vepkqnenrlsdTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPK 748
Cdd:NF033839  405 ------------PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPK 472
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 47578105   749 QKNEGRPETPKhrHDNRR---DSGKPSTEKkpEVSKHKQDTKSDS 790
Cdd:NF033839  473 PEVKPQPEKPK--PDNSKpqaDDKKPSTPN--NLSKDKQPSNQAS 513
PTZ00121 PTZ00121
MAEBL; Provisional
476-1092 3.81e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   476 EIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQA 555
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   556 SITQ-DSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENhpetPKKKSDpELSKSEMKQSESRLAESKPNENRlvetK 634
Cdd:PTZ00121 1362 AEEKaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKAD-ELKKAAAAKKKADEAKKKAEEKK----K 1432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   635 SSENKLETKVETQTEELKQnesRTTECKQNEStiVEPKQNENRLSDtKPNDNKQNNGRSETTKSRPETPKQKGES--RPE 712
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADEAKK---KAEEAKKAEE--AKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKADEakKAA 1506
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   713 TPKQKSDghpETPKQKgdgrpETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDS---GKPSTEKKPEVSKHKQDTKSD 789
Cdd:PTZ00121 1507 EAKKKAD---EAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAeelKKAEEKKKAEEAKKAEEDKNM 1578
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   790 SPRlkseRAEALKQRPDGRSV-------------SESLRRDHDNKQKSDD--RGESERHRGDQSR------VRRPETLRS 848
Cdd:PTZ00121 1579 ALR----KAEEAKKAEEARIEevmklyeeekkmkAEEAKKAEEAKIKAEElkKAEEEKKKVEQLKkkeaeeKKKAEELKK 1654
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   849 SSRN-------------EHGIKSDSSKTDKLERKHRHESGDSRE---------RPSSGEQKSRPDSPRvKQGDSNKSRSD 906
Cdd:PTZ00121 1655 AEEEnkikaaeeakkaeEDKKKAEEAKKAEEDEKKAAEALKKEAeeakkaeelKKKEAEEKKKAEELK-KAEEENKIKAE 1733
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   907 KLGFKSPTSK----DDKRTEGNKSKVDTNKAHPDNKAEfpsyllggRSGALKNFVIPKIKRDKDgnvtqETKKMEMKGEP 982
Cdd:PTZ00121 1734 EAKKEAEEDKkkaeEAKKDEEEKKKIAHLKKEEEKKAE--------EIRKEKEAVIEEELDEED-----EKRRMEVDKKI 1800
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   983 KDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIK-------NKPSKSNKGSIDQSVLKELPPEL 1055
Cdd:PTZ00121 1801 KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEkhkfnknNENGEDGNKEADFNKEKDLKEDD 1880
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 47578105  1056 LAEIESTMplcERVKMNK----RKRSTVNEKPKYAEISSDE 1092
Cdd:PTZ00121 1881 EEEIEEAD---EIEKIDKddieREIPNNNMAGKNNDIIDDK 1918
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
591-943 1.73e-10

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 66.33  E-value: 1.73e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   591 STPEN----HPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLE-TKVETQTEELKQNESRTTECKQ-- 663
Cdd:NF033839  162 PQPENpehqKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDiQKHHLQKEKHRQIVALIKELDElk 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   664 --------NESTIVEPKQNENRL-SDTKPNDNKQNNGRSETT-----KSRPETPKQKGESRPETPKQKSDGHPETPKQKG 729
Cdd:NF033839  242 kqalseidNVNTKVEIENTVHKIfADMDAVVTKFKKGLTQDTpkepgNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEV 321
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   730 DGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPstEKKPEVSKHKQDTKSDSPRLKSE-RAEALKQRPDGR 808
Cdd:NF033839  322 KPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKP--EVKPQPEKPKPEVKPQPETPKPEvKPQPEKPKPEVK 399
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   809 SVSEslrrdhdnKQKSDDRGESERHRGD---QSRVRRPETLRSSSRNEHGIKSDsSKTDKLERKHRHESGDSRERPSSge 885
Cdd:NF033839  400 PQPE--------KPKPEVKPQPEKPKPEvkpQPEKPKPEVKPQPEKPKPEVKPQ-PEKPKPEVKPQPETPKPEVKPQP-- 468
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47578105   886 QKSRPD---SPRVKQGDSNKSRSDKlgfKSPTSKDDKRTEGNKSK--VDTNKAHPDNKAEFPS 943
Cdd:NF033839  469 EKPKPEvkpQPEKPKPDNSKPQADD---KKPSTPNNLSKDKQPSNqaSTNEKATNKPKKSLPS 528
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
591-778 1.21e-07

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 56.24  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    591 STPENHPETPKKKSDPELSKSEMK---QSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTEckqnest 667
Cdd:TIGR02223   51 SKQANEPETLQPKNQTENGETAADlppKPEERWSYIEELEAREVLINDPEEPSNGGGVEESAQLTAEQRQLLE------- 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    668 ivePKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKsdghPETPKQKGDGRPETPKQKGESRPETP 747
Cdd:TIGR02223  124 ---QMQADMRAAEKVLATAPSEQTVAVEARKQTAEKKPQKARTAEAQKTP----VETEKIASKVKEAKQKQKALPKQTAE 196
                          170       180       190
                   ....*....|....*....|....*....|.
gi 47578105    748 KQKNEGRPETPkhRHDNRRDSGKPSTEKKPE 778
Cdd:TIGR02223  197 TQSNSKPIETA--PKADKADKTKPKPKEKAE 225
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
476-894 5.96e-07

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 55.47  E-value: 5.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   476 EIERIERESAIERERFSKEVQDK-DKPLKKRKQDSYPQEAGG---ATGGNRPASQETGSTGNGSRPALmvsidlhqagrv 551
Cdd:PTZ00449  484 EIKKLIKKSKKKLAPIEEEDSDKhDEPPEGPEASGLPPKAPGdkeGEEGEHEDSKESDEPKEGGKPGE------------ 551
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   552 dsqasiTQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESK--PNENR 629
Cdd:PTZ00449  552 ------TKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdiPKSPK 625
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   630 LVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIV--EPKQNEN----------RLSDTKPNDNKQNNGRSETTK 697
Cdd:PTZ00449  626 RPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPpfDPKFKEKfyddyldaaaKSKETKTTVVLDESFESILKE 705
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   698 SRPETPKQKGES-RPETPKQKSDghPETPKQKgDGRPETPKQKGESRPETPKQKNEGRPETPKHRH------------DN 764
Cdd:PTZ00449  706 TLPETPGTPFTTpRPLPPKLPRD--EEFPFEP-IGDPDAEQPDDIEFFTPPEEERTFFHETPADTPlpdilaeefkeeDI 782
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   765 RRDSGKP-STEKKPEV-SKHKQDTKSDSPRL--KSERAEALK-QRPDGRSVSESLRRDHDNKQKSDDRGESerhRGDQSR 839
Cdd:PTZ00449  783 HAETGEPdEAMKRPDSpSEHEDKPPGDHPSLpkKRHRLDGLAlSTTDLESDAGRIAKDASGKIVKLKRSKS---FDDLTT 859
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47578105   840 VRRPETLRSSSR----NEHGIKSDSSKTDKLERKHRHESGDSR--ERPSSGEQKSRPDSPR 894
Cdd:PTZ00449  860 VEEAEEMGAEARkivvDDDGTEADDEDTHPPEEKHKSEVRRRRppKKPSKPKKPSKPKKPK 920
Caldesmon pfam02029
Caldesmon;
480-890 3.98e-04

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 45.63  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    480 IERESAIERERFSKEVQDKdkplkkRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGrvdsqasitq 559
Cdd:pfam02029    1 IEDEEEAARERRRRAREER------RRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAF---------- 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    560 dSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMK-QSESRLAESKPNENRLVETKSSEN 638
Cdd:pfam02029   65 -LDRTAKREERRQKRLQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEeKRDSRLGRYKEEETEIREKEYQEN 143
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    639 KLET--------------KVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNdnkqnngrsettksrpeTPK 704
Cdd:pfam02029  144 KWSTevrqaeeegeeeedKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRG-----------------HPE 206
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    705 QKGESRPEtpKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRpetpkhrhdnRRDSGKPSTEKKPevSKHKQ 784
Cdd:pfam02029  207 VKSQNGEE--EVTKLKVTTKRRQGGLSQSQEREEEAEVFLEAEQKLEELR----------RRRQEKESEEFEK--LRQKQ 272
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    785 dtksdsPRLKSERAEALKQRPDGRSV-SESLRRDHDNKQKSDDRGESERHRGDQSRVRR-----------PETlrSSSRN 852
Cdd:pfam02029  273 ------QEAELELEELKKKREERRKLlEEEEQRRKQEEAERKLREEEEKRRMKEEIERRraeaaekrqklPED--SSSEG 344
                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 47578105    853 EHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRP 890
Cdd:pfam02029  345 KKPFKCFSPKGSSLKITERAEFLNKSLQKSSSVKKTHP 382
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
475-759 1.68e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.85  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   475 AEIERIERESAIERERFSKEV--QDKDKPlKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPAlmvsidlhqagrvD 552
Cdd:NF033838  233 AEEEAKRRADAKLKEAVEKNVatSEQDKP-KRRAKRGVLGEPATPDKKENDAKSSDSSVGEETLPS-------------P 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   553 SQASITQDSDSIKKPEEI-KQCNDapvsvlQEDivgslkSTPENHPETPKKKSDPELSKSEMKQSESRLaeskpnenRLV 631
Cdd:NF033838  299 SLKPEKKVAEAEKKVEEAkKKAKD------QKE------EDRRNYPTNTYKTLELEIAESDVKVKEAEL--------ELV 358
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   632 ETKSSENKLETKVETQTEELkqnesrttECKQNESTIVEPKQNENRlsdTKPNDNKQNNGRSETTKSRP-ETPKQKGESR 710
Cdd:NF033838  359 KEEAKEPRNEEKIKQAKAKV--------ESKKAEATRLEKIKTDRK---KAEEEAKRKAAEEDKVKEKPaEQPQPAPAPQ 427
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   711 PETPKQKSDGHPETPK-QKGDGR----------PETPKQKGESRPetPKQKNEGRPETPK 759
Cdd:NF033838  428 PEKPAPKPEKPAEQPKaEKPADQqaeedyarrsEEEYNRLTQQQP--PKTEKPAQPSTPK 485
 
Name Accession Description Interval E-value
SCC2 cd23958
Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid ...
1263-2473 0e+00

Sister chromatid cohesion protein 2 and homologs; This family includes Sister chromatid cohesion protein 2 (Scc2) and its homolog (Scc2 homolog, also called Nipped-B-like protein or NIPBL). Scc2/NIPBL and Scc4 form a complex that is responsible for loading the cohesin protein onto sister chromatids during mitosis and meiosis. Cohesin is a ring-shaped protein complex that encircles the sister chromatids and helps to hold them together until they are ready to be separated during cell division. In addition to its role in chromosome segregation, cohesin also plays important roles in other cellular processes such as transcription, chromosome condensation, and DNA repair.


Pssm-ID: 467937 [Multi-domain]  Cd Length: 1197  Bit Score: 1442.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1263 VKVLNILEKNIQDGSKLStLLNHNNDTEEEERLWRDLIMERVTKSADACLTtinIMTSPNMPKAVYIEDVIERVIQYTKF 1342
Cdd:cd23958    3 VRLLTILERNIRDGESLD-LDLDESQEDDEERLWLLERIDRALEAADASLT---ILTSPGLPKQLYSEDLIERVVDFLKF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1343 HLQNTLYPQYDPVYRLDPHGGGLlssKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPF 1422
Cdd:cd23958   79 QLENTIYPAYDPVYRSDSSAKAG---KKKRAKASSKKKKSVSTLLNKLCELLSLLAELLSLQSLTDSVILQLVYLAISPF 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1423 FVE----NVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDmdgepmYIQMVTALVLQLI 1498
Cdd:cd23958  156 FVEnavsNVDELQLSALKLLTSIFSRYPDQRQFIIEEILSSLAKLPSSKRNLRQFRLNDGK------SIQMVTALLLQLV 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1499 QCVVHLPSSEKDSN-----AEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSK--QGEEDYRPLFENFVQDLLS 1571
Cdd:cd23958  230 QSSVKLPNLEKESSrdkslEEDSDELLEDEESALAKSYESAVRIASYFLSFLLQKCTKKkkEKDTDYRPLFENFVQDLLT 309
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1572 TVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTskmdqgsierilkqvsggedeiQQL 1651
Cdd:cd23958  310 VLNLPEWPAAELLLSLLGRLLVSIFSNKKTDANARVMALDLLGLIAARLRKDALA----------------------EEL 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1652 QKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKsqkdeessegthhAKEIETTGQIMHRAENRKKFLRSIi 1731
Cdd:cd23958  368 QKALLDYLAENSSSDPSLESARGFYLAQWLRDLSNELEKAEK-------------AAEEEDTILKLELSELRKKFLDSK- 433
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1732 kttpsqFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLD 1811
Cdd:cd23958  434 ------ILSKEEEASPLSREDAKLLYRALASQRPLSQSFDPILKQLLSSLDEPAVTLRTKALKALSLVVEADPSILGDPD 507
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1812 MQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVK 1891
Cdd:cd23958  508 VQRAVEGRLLDSSASVREAAVELVGKYISSRPDLAEQYYEMIAERILDTGVSVRKRVIKILRDIYLRTPDFEIKVDICVR 587
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1892 MIRRVND-EEGIKKLVNETFQKLWFTPTPHN-----DKEAMTRKILNITDVVAACRdTGYDWFEQLLQNLLKSEEDSSYK 1965
Cdd:cd23958  588 LLRRINDeEESIKDLARKTFQELWFTPFPESsspaqDKESLAERVLLIVDVVAACR-KGLDLLEQLLKRLLKSKEDKEDK 666
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1966 PVKKACTQLVDNLVEHILKYEESLADSdnkgvNSGRLVACITTLFLFSKIRP-QLMVKHAMTMQPYLTTKCSTQNDFMVI 2044
Cdd:cd23958  667 SVRKACKQLVDCLVELILELEEDDDES-----SESDLVACLSTLHLFAKADPkLLLVEHAETLQPYLKSKCSTREDQQVL 741
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2045 CNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQH 2124
Cdd:cd23958  742 RYVLRILRSVLPLLSHPSESFLEELEEDLLKLLLKHSVTVLQEAIACLCAVVNKLTKNYERLRKALQSCLKLLRKYKRQA 821
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2125 QEDPNNTsllTNKPALLRSLFTVGALCRHFDFDLEDFKGN-----SKVNIKDKVLELLMYFTKHS-DEEVQTKAIIGLGF 2198
Cdd:cd23958  822 NLDPSSL---KEDPKLLRLLYILGLLARYCDFDSERDDFEkaplkTKESVKELVFDLLLFFTKPPiDEDVRKKALQALGF 898
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2199 AFIQHPSLMFEQEVKNLYNNILSDknSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQ-----EDLKEMGDVSSG 2273
Cdd:cd23958  899 LCIAHPKLFLSPEVLKLLDEILAS--GSLKLKLQVLRNLQEFLQAEEKRMEAADAEWKKNSKAadvkvLDGKEMGDADSG 976
                       1050      1060      1070      1080      1090      1100      1110      1120
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2274 MSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFI 2353
Cdd:cd23958  977 VASSIMQRYLKDILELCLSSDSQVRLAALKVLELILRQGLVHPIQCVPTLIALETDPNPAIRKLALRLLKELHEKYESLV 1056
                       1130      1140      1150      1160      1170      1180      1190      1200
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 2354 HMKAVAGMKMSYQVQQAINTclKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDD------TAKTDVTM 2427
Cdd:cd23958 1057 ESKYLEGVRLAFQYQKRLAG--DTRGRGFRTDSPPTALLGRLYSLLRGNRKSRRKFLKSLLKLFDFdlkkssDSPSDLDF 1134
                       1210      1220      1230      1240
                 ....*....|....*....|....*....|....*....|....*..
gi 47578105 2428 LLYIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSF-KESMV 2473
Cdd:cd23958 1135 LLFLAENLAFLPYQTQDEPLFVIHTIDRILSVTGSSLLQAIaKASQA 1181
Nipped-B_C pfam12830
Sister chromatid cohesion C-terminus; This domain lies towards the C-terminus of nipped-B or ...
2275-2456 7.31e-70

Sister chromatid cohesion C-terminus; This domain lies towards the C-terminus of nipped-B or sister chromatid cohesion proteins.


Pssm-ID: 463722  Cd Length: 180  Bit Score: 232.81  E-value: 7.31e-70
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   2275 SSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIH 2354
Cdd:pfam12830    1 CSALVQRYLKHILEICLSSDDQVRLLALEVLALILRQGLVHPKECIPTLIALETSPNPYIRKLAFELHKELHEKHESLLE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   2355 MKAVAGMKMSYQVQQAINTClkdpvrgfRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDD------TAKTDVTML 2428
Cdd:pfam12830   81 SRYMEGIRLAFEYQRRVLSG--------ATLEPPTSFLSLLYSLLRSNKKSRKKFLKSLVKLFFDldlsseSSPSDLDFL 152
                          170       180
                   ....*....|....*....|....*...
gi 47578105   2429 LYIADNLACFPYQTQEEPLFIMHHIDIT 2456
Cdd:pfam12830  153 RFLAENLAFLPYQTQDEVLFLIHHIDRI 180
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
597-832 2.03e-15

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 82.51  E-value: 2.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   597 PETPKKKSDPELS--KSEMKQS-ESRLAESKPN-ENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNEstiVEPK 672
Cdd:NF033839  281 QDTPKEPGNKKPSapKPGMQPSpQPEKKEVKPEpETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPE---VKPQ 357
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   673 qnenrLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNE 752
Cdd:NF033839  358 -----PEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVK 432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   753 GRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPR------LKSERAEALKQRPDGR--SVSESLRRDhdnKQKS 824
Cdd:NF033839  433 PQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKpevkpqPEKPKPDNSKPQADDKkpSTPNNLSKD---KQPS 509

                  ....*...
gi 47578105   825 DDRGESER 832
Cdd:NF033839  510 NQASTNEK 517
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
590-790 2.42e-13

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 75.58  E-value: 2.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   590 KSTPENHPETPKKKSDPELSKsEMKQSESRLAESKPNENRLVETKSSENKLETkvETQTEELK-QNESRTTECKQNESTi 668
Cdd:NF033839  329 KPEVKPQPEKPKPEVKPQLET-PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQP--ETPKPEVKpQPEKPKPEVKPQPEK- 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   669 vepkqnenrlsdTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPK 748
Cdd:NF033839  405 ------------PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPK 472
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 47578105   749 QKNEGRPETPKhrHDNRR---DSGKPSTEKkpEVSKHKQDTKSDS 790
Cdd:NF033839  473 PEVKPQPEKPK--PDNSKpqaDDKKPSTPN--NLSKDKQPSNQAS 513
PTZ00121 PTZ00121
MAEBL; Provisional
476-1092 3.81e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 3.81e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   476 EIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQA 555
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   556 SITQ-DSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENhpetPKKKSDpELSKSEMKQSESRLAESKPNENRlvetK 634
Cdd:PTZ00121 1362 AEEKaEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE----DKKKAD-ELKKAAAAKKKADEAKKKAEEKK----K 1432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   635 SSENKLETKVETQTEELKQnesRTTECKQNEStiVEPKQNENRLSDtKPNDNKQNNGRSETTKSRPETPKQKGES--RPE 712
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADEAKK---KAEEAKKAEE--AKKKAEEAKKAD-EAKKKAEEAKKADEAKKKAEEAKKKADEakKAA 1506
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   713 TPKQKSDghpETPKQKgdgrpETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDS---GKPSTEKKPEVSKHKQDTKSD 789
Cdd:PTZ00121 1507 EAKKKAD---EAKKAE-----EAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAeelKKAEEKKKAEEAKKAEEDKNM 1578
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   790 SPRlkseRAEALKQRPDGRSV-------------SESLRRDHDNKQKSDD--RGESERHRGDQSR------VRRPETLRS 848
Cdd:PTZ00121 1579 ALR----KAEEAKKAEEARIEevmklyeeekkmkAEEAKKAEEAKIKAEElkKAEEEKKKVEQLKkkeaeeKKKAEELKK 1654
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   849 SSRN-------------EHGIKSDSSKTDKLERKHRHESGDSRE---------RPSSGEQKSRPDSPRvKQGDSNKSRSD 906
Cdd:PTZ00121 1655 AEEEnkikaaeeakkaeEDKKKAEEAKKAEEDEKKAAEALKKEAeeakkaeelKKKEAEEKKKAEELK-KAEEENKIKAE 1733
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   907 KLGFKSPTSK----DDKRTEGNKSKVDTNKAHPDNKAEfpsyllggRSGALKNFVIPKIKRDKDgnvtqETKKMEMKGEP 982
Cdd:PTZ00121 1734 EAKKEAEEDKkkaeEAKKDEEEKKKIAHLKKEEEKKAE--------EIRKEKEAVIEEELDEED-----EKRRMEVDKKI 1800
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   983 KDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIK-------NKPSKSNKGSIDQSVLKELPPEL 1055
Cdd:PTZ00121 1801 KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEkhkfnknNENGEDGNKEADFNKEKDLKEDD 1880
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|.
gi 47578105  1056 LAEIESTMplcERVKMNK----RKRSTVNEKPKYAEISSDE 1092
Cdd:PTZ00121 1881 EEEIEEAD---EIEKIDKddieREIPNNNMAGKNNDIIDDK 1918
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
591-943 1.73e-10

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 66.33  E-value: 1.73e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   591 STPEN----HPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLE-TKVETQTEELKQNESRTTECKQ-- 663
Cdd:NF033839  162 PQPENpehqKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDiQKHHLQKEKHRQIVALIKELDElk 241
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   664 --------NESTIVEPKQNENRL-SDTKPNDNKQNNGRSETT-----KSRPETPKQKGESRPETPKQKSDGHPETPKQKG 729
Cdd:NF033839  242 kqalseidNVNTKVEIENTVHKIfADMDAVVTKFKKGLTQDTpkepgNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEV 321
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   730 DGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPstEKKPEVSKHKQDTKSDSPRLKSE-RAEALKQRPDGR 808
Cdd:NF033839  322 KPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKP--EVKPQPEKPKPEVKPQPETPKPEvKPQPEKPKPEVK 399
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   809 SVSEslrrdhdnKQKSDDRGESERHRGD---QSRVRRPETLRSSSRNEHGIKSDsSKTDKLERKHRHESGDSRERPSSge 885
Cdd:NF033839  400 PQPE--------KPKPEVKPQPEKPKPEvkpQPEKPKPEVKPQPEKPKPEVKPQ-PEKPKPEVKPQPETPKPEVKPQP-- 468
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47578105   886 QKSRPD---SPRVKQGDSNKSRSDKlgfKSPTSKDDKRTEGNKSK--VDTNKAHPDNKAEFPS 943
Cdd:NF033839  469 EKPKPEvkpQPEKPKPDNSKPQADD---KKPSTPNNLSKDKQPSNqaSTNEKATNKPKKSLPS 528
Cohesin_HEAT pfam12765
HEAT repeat associated with sister chromatid cohesion; This HEAT repeat is found most ...
1794-1835 3.03e-09

HEAT repeat associated with sister chromatid cohesion; This HEAT repeat is found most frequently in sister chromatid cohesion proteins such as Nipped-B. HEAT repeats are found tandemly repeated in many proteins, and they appear to serve as flexible scaffolding on which other components can assemble.


Pssm-ID: 403845 [Multi-domain]  Cd Length: 42  Bit Score: 54.39  E-value: 3.03e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 47578105   1794 KCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELL 1835
Cdd:pfam12765    1 KALSSLVEKDPSILDSPDVKEAISRRLTDSSPSVRDAALELL 42
PTZ00121 PTZ00121
MAEBL; Provisional
607-1192 3.68e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 3.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   607 ELSKSE--MKQSESRLAEskpNENRLVETKSSENKLETKVETQTEELKQN--ESRTTECKQNESTIVEPKQNENRLSDTK 682
Cdd:PTZ00121 1192 ELRKAEdaRKAEAARKAE---EERKAEEARKAEDAKKAEAVKKAEEAKKDaeEAKKAEEERNNEEIRKFEEARMAHFARR 1268
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   683 PNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDghpETPKQKGDGR-PETPKQKGES---RPETPKQKNE---GRP 755
Cdd:PTZ00121 1269 QAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAD---EAKKKAEEAKkADEAKKKAEEakkKADAAKKKAEeakKAA 1345
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   756 ETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKsdsprlksERAEALKQRPDG-RSVSESLRRDHDNKQKSDD--RGESER 832
Cdd:PTZ00121 1346 EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK--------KKADAAKKKAEEkKKADEAKKKAEEDKKKADElkKAAAAK 1417
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   833 HRGDQSRVRRPETLRSssrNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDspRVKQGDSNKSRSDKLGFKS 912
Cdd:PTZ00121 1418 KKADEAKKKAEEKKKA---DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD--EAKKKAEEAKKADEAKKKA 1492
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   913 PTSKDdKRTEGNKSKVDTNKAHPDNKAEfpsyllggrsgalknfvipKIKRDKDGNVTQETKKME--MKGEPKDKVEKIG 990
Cdd:PTZ00121 1493 EEAKK-KADEAKKAAEAKKKADEAKKAE-------------------EAKKADEAKKAEEAKKADeaKKAEEKKKADELK 1552
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   991 LVEDLNKGAkpvvvlQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVK 1070
Cdd:PTZ00121 1553 KAEELKKAE------EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1071 MNKRKRSTVN--------EKPKYAEISSDEDNDSDEAFESSRKRH---KKDDDKAWEYEERDRRSSGDHRRSGHSHEGRR 1139
Cdd:PTZ00121 1627 KAEEEKKKVEqlkkkeaeEKKKAEELKKAEEENKIKAAEEAKKAEedkKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 47578105  1140 SSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKkekqKKRKAYEPKLTPEE 1192
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE----DKKKAEEAKKDEEE 1755
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
704-1139 5.59e-08

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 58.93  E-value: 5.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   704 KQKGESRPETPKQKSDGHpetpkqkgDGRPETPKQKGESrPETPkqkneGRPETPKHRHDNRRDSGKPSTEKKPEVSKHK 783
Cdd:PTZ00449  490 KKSKKKLAPIEEEDSDKH--------DEPPEGPEASGLP-PKAP-----GDKEGEEGEHEDSKESDEPKEGGKPGETKEG 555
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   784 QDTKSDSP--RLKSERAEALKQRPDGRSVSESLRRDHDNKQksddrgeSERHRGDQSRVRRPETLRSSSrnehgikSDSS 861
Cdd:PTZ00449  556 EVGKKPGPakEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKK-------PKRPRSAQRPTRPKSPKLPEL-------LDIP 621
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   862 KTDKlerkhRHESGDSRERPSSGEQKS---RPDSPRVKQgDSNKSRSDKLGFkSPTSK----DDKRTEGNKSKVDTNKAH 934
Cdd:PTZ00449  622 KSPK-----RPESPKSPKRPPPPQRPSspeRPEGPKIIK-SPKPPKSPKPPF-DPKFKekfyDDYLDAAAKSKETKTTVV 694
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   935 PDNKAEF----PSYLLGGRSGALKNFVIPKIKRDKDGNVT-------QETKKMEMKGEPKDKVEKIGlvEDLNKGAKPVV 1003
Cdd:PTZ00449  695 LDESFESilkeTLPETPGTPFTTPRPLPPKLPRDEEFPFEpigdpdaEQPDDIEFFTPPEEERTFFH--ETPADTPLPDI 772
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1004 VLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSnkGSIDQSVLKELPPELLA----EIESTM------PLCERVKMNK 1073
Cdd:PTZ00449  773 LAEEFKEEDIHAETGEPDEAMKRPDSPSEHEDKPP--GDHPSLPKKRHRLDGLAlsttDLESDAgriakdASGKIVKLKR 850
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47578105  1074 RKR----STVNEK----PKYAEISSDEDNDS--DEAFESSRKRHKKdddkaweyEERDRRSSGDHRRSGHSHEGRR 1139
Cdd:PTZ00449  851 SKSfddlTTVEEAeemgAEARKIVVDDDGTEadDEDTHPPEEKHKS--------EVRRRRPPKKPSKPKKPSKPKK 918
ftsN TIGR02223
cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a ...
591-778 1.21e-07

cell division protein FtsN; FtsN is a poorly conserved protein active in cell division in a number of Proteobacteria. The N-terminal 30 residue region tends to by Lys/Arg-rich, and is followed by a membrane-spanning region. This is followed by an acidic low-complexity region of variable length and a well-conserved C-terminal domain of two tandem regions matched by pfam05036 (Sporulation related repeat), found in several cell division and sporulation proteins. The role of FtsN as a suppressor for other cell division mutations is poorly understood; it may involve cell wall hydrolysis. [Cellular processes, Cell division]


Pssm-ID: 274041 [Multi-domain]  Cd Length: 298  Bit Score: 56.24  E-value: 1.21e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    591 STPENHPETPKKKSDPELSKSEMK---QSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTEckqnest 667
Cdd:TIGR02223   51 SKQANEPETLQPKNQTENGETAADlppKPEERWSYIEELEAREVLINDPEEPSNGGGVEESAQLTAEQRQLLE------- 123
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    668 ivePKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKsdghPETPKQKGDGRPETPKQKGESRPETP 747
Cdd:TIGR02223  124 ---QMQADMRAAEKVLATAPSEQTVAVEARKQTAEKKPQKARTAEAQKTP----VETEKIASKVKEAKQKQKALPKQTAE 196
                          170       180       190
                   ....*....|....*....|....*....|.
gi 47578105    748 KQKNEGRPETPkhRHDNRRDSGKPSTEKKPE 778
Cdd:TIGR02223  197 TQSNSKPIETA--PKADKADKTKPKPKEKAE 225
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
476-894 5.96e-07

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 55.47  E-value: 5.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   476 EIERIERESAIERERFSKEVQDK-DKPLKKRKQDSYPQEAGG---ATGGNRPASQETGSTGNGSRPALmvsidlhqagrv 551
Cdd:PTZ00449  484 EIKKLIKKSKKKLAPIEEEDSDKhDEPPEGPEASGLPPKAPGdkeGEEGEHEDSKESDEPKEGGKPGE------------ 551
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   552 dsqasiTQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESK--PNENR 629
Cdd:PTZ00449  552 ------TKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdiPKSPK 625
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   630 LVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIV--EPKQNEN----------RLSDTKPNDNKQNNGRSETTK 697
Cdd:PTZ00449  626 RPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPpfDPKFKEKfyddyldaaaKSKETKTTVVLDESFESILKE 705
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   698 SRPETPKQKGES-RPETPKQKSDghPETPKQKgDGRPETPKQKGESRPETPKQKNEGRPETPKHRH------------DN 764
Cdd:PTZ00449  706 TLPETPGTPFTTpRPLPPKLPRD--EEFPFEP-IGDPDAEQPDDIEFFTPPEEERTFFHETPADTPlpdilaeefkeeDI 782
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   765 RRDSGKP-STEKKPEV-SKHKQDTKSDSPRL--KSERAEALK-QRPDGRSVSESLRRDHDNKQKSDDRGESerhRGDQSR 839
Cdd:PTZ00449  783 HAETGEPdEAMKRPDSpSEHEDKPPGDHPSLpkKRHRLDGLAlSTTDLESDAGRIAKDASGKIVKLKRSKS---FDDLTT 859
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47578105   840 VRRPETLRSSSR----NEHGIKSDSSKTDKLERKHRHESGDSR--ERPSSGEQKSRPDSPR 894
Cdd:PTZ00449  860 VEEAEEMGAEARkivvDDDGTEADDEDTHPPEEKHKSEVRRRRppKKPSKPKKPSKPKKPK 920
PRK12678 PRK12678
transcription termination factor Rho; Provisional
693-907 1.07e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 51.06  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   693 SETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPS 772
Cdd:PRK12678   67 AATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAG 146
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   773 TEKKPEVSKHKQDTKSDSPRLKSERaealkQRPDGRsvseslRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRN 852
Cdd:PRK12678  147 EGGEQPATEARADAAERTEEEERDE-----RRRRGD------REDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRR 215
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 47578105   853 EHGiksdssktDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDK 907
Cdd:PRK12678  216 EER--------GRRDGGDRRGRRRRRDRRDARGDDNREDRGDRDGDDGEGRGGRR 262
PRK12678 PRK12678
transcription termination factor Rho; Provisional
692-889 2.58e-05

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 49.90  E-value: 2.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   692 RSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKP 771
Cdd:PRK12678   77 ARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGEGGEQPATEA 156
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   772 STEKKPEVSKHKQDTKSD--SPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPEtlRSS 849
Cdd:PRK12678  157 RADAAERTEEEERDERRRrgDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRR--RRD 234
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 47578105   850 SRNEHGiksDSSKTDKLERKHRHESGDSRERPSSGEQKSR 889
Cdd:PRK12678  235 RRDARG---DDNREDRGDRDGDDGEGRGGRRGRRFRDRDR 271
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
878-1113 5.82e-05

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 48.89  E-value: 5.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   878 RERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNK---AEFPSYLLGGRSGALK 954
Cdd:PTZ00108 1146 EVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKrklDDKPDNKKSNSSGSDQ 1225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   955 NFVIPKIKRDKDGNVTQETKKmEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNK 1034
Cdd:PTZ00108 1226 EDDEEQKTKPKKSSVKRLKSK-KNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSS 1304
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1035 PSKSNKGSIDQSVLKELPPELLAEIESTmplcERVKMNKR-------KRSTVNEKPKYAEISSDEDNDSDEAFESSRKRH 1107
Cdd:PTZ00108 1305 PTKKKVKKRLEGSLAALKKKKKSEKKTA----RKKKSKTRvkqasasQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDED 1380

                  ....*.
gi 47578105  1108 KKDDDK 1113
Cdd:PTZ00108 1381 DEDDED 1386
dnaA PRK14086
chromosomal replication initiator protein DnaA;
700-889 2.23e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 46.74  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   700 PETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPK---QKGESRPETPKQKNEGR----PETPKHRHDNRRDSGKPS 772
Cdd:PRK14086   97 PPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPrqdQLPTARPAYPAYQQRPEpgawPRAADDYGWQQQRLGFPP 176
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   773 TEKKPEVSkhkqdtkSDSPRLKSERAEALKQRPDgrsvseslrRDHDNKQKSDDRGESERHRGDqsRVRRPETLRSSSRN 852
Cdd:PRK14086  177 RAPYASPA-------SYAPEQERDREPYDAGRPE---------YDQRRRDYDHPRPDWDRPRRD--RTDRPEPPPGAGHV 238
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 47578105   853 EHGIKSDSSKTDKLERKHR-----HESGDSRERPSSGEQKSR 889
Cdd:PRK14086  239 HRGGPGPPERDDAPVVPIRpsapgPLAAQPAPAPGPGEPTAR 280
Caldesmon pfam02029
Caldesmon;
480-890 3.98e-04

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 45.63  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    480 IERESAIERERFSKEVQDKdkplkkRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGrvdsqasitq 559
Cdd:pfam02029    1 IEDEEEAARERRRRAREER------RRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAF---------- 64
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    560 dSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMK-QSESRLAESKPNENRLVETKSSEN 638
Cdd:pfam02029   65 -LDRTAKREERRQKRLQEALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEeKRDSRLGRYKEEETEIREKEYQEN 143
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    639 KLET--------------KVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNdnkqnngrsettksrpeTPK 704
Cdd:pfam02029  144 KWSTevrqaeeegeeeedKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRG-----------------HPE 206
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    705 QKGESRPEtpKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRpetpkhrhdnRRDSGKPSTEKKPevSKHKQ 784
Cdd:pfam02029  207 VKSQNGEE--EVTKLKVTTKRRQGGLSQSQEREEEAEVFLEAEQKLEELR----------RRRQEKESEEFEK--LRQKQ 272
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    785 dtksdsPRLKSERAEALKQRPDGRSV-SESLRRDHDNKQKSDDRGESERHRGDQSRVRR-----------PETlrSSSRN 852
Cdd:pfam02029  273 ------QEAELELEELKKKREERRKLlEEEEQRRKQEEAERKLREEEEKRRMKEEIERRraeaaekrqklPED--SSSEG 344
                          410       420       430
                   ....*....|....*....|....*....|....*...
gi 47578105    853 EHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRP 890
Cdd:pfam02029  345 KKPFKCFSPKGSSLKITERAEFLNKSLQKSSSVKKTHP 382
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
590-838 4.13e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.19  E-value: 4.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   590 KSTPENHPETPKKKSDPELSKSEMKQSESrLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIV 669
Cdd:PTZ00108 1156 QRLKSKTKGKASKLRKPKLKKKEKKKKKS-SADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTK 1234
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   670 EPKQNENRLSDTKPNDnKQNNGRSETTKSRPETPKQKGESRPEtPKQKSDGHPETPKQkgdgrPETPKQKGESRPETPKQ 749
Cdd:PTZ00108 1235 PKKSSVKRLKSKKNNS-SKSSEDNDEFSSDDLSKEGKPKNAPK-RVSAVQYSPPPPSK-----RPDGESNGGSKPSSPTK 1307
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   750 KNEGRPETPKhrhdnrrdSGKPSTEKKPEVSKHKQDtKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGE 829
Cdd:PTZ00108 1308 KKVKKRLEGS--------LAALKKKKKSEKKTARKK-KSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSED 1378

                  ....*....
gi 47578105   830 SERHRGDQS 838
Cdd:PTZ00108 1379 EDDEDDEDD 1387
PRK12678 PRK12678
transcription termination factor Rho; Provisional
692-899 4.86e-04

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 45.67  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   692 RSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKP 771
Cdd:PRK12678   88 RQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGEGGEQPATEARADAAERTEEE 167
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   772 STEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPEtlRSSSR 851
Cdd:PRK12678  168 ERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRRDRREQGDRREERGRRDGGDRRGRRRRRDRRDARG--DDNRE 245
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 47578105   852 NEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPdsPRVKQGD 899
Cdd:PRK12678  246 DRGDRDGDDGEGRGGRRGRRFRDRDRRGRRGGDGGNERE--PELREDD 291
PDS5 cd19953
Sister chromatid cohesion protein PDS5; Pds5 plays a crucial role in sister chromatid cohesion. ...
1786-1882 4.91e-04

Sister chromatid cohesion protein PDS5; Pds5 plays a crucial role in sister chromatid cohesion. Together with WapI and Scc3, it is involved in the release of the cohesin complex from chromosomes during S phase. The core of the cohesin complex consists of a coiled-coiled heterodimer of Smc1 and Smc30, together with Scc1 (also called kleisin). Pds5 interacts with Scc1 via a conserved patch on the surface of its heat repeats. Pds5 also promotes the acetylation of Smc3 that protects cohesin from releasing activity in G2 phase.


Pssm-ID: 410996 [Multi-domain]  Cd Length: 630  Bit Score: 45.59  E-value: 4.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105 1786 IAVRTKAMKCLSEVVAVDPS-ILARldmqrgVH--------GRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIER 1856
Cdd:cd19953  259 VDVRLLATKLLGKMFAEKGSaGFAQ------TYpslwkeflGRFNDKSPEVRLAWVESAKHILLNHPDLAEDILEALKKR 332
                         90       100
                 ....*....|....*....|....*.
gi 47578105 1857 ILDTGISVRKRVIKILRDICIEQPTF 1882
Cdd:cd19953  333 LLDPDEKVRLAAVKAICDLAYEDLLH 358
PDS5 pfam20168
Sister chromatid cohesion protein PDS5 protein; This entry represents the Sister chromatid ...
1785-1928 5.33e-04

Sister chromatid cohesion protein PDS5 protein; This entry represents the Sister chromatid cohesion protein PDS5. The large PDS5 molecule is exclusively alpha helical, composed of a large number of HEAT-like repeats and helical extensions/additions that deviate from the HEAT repeat pattern.


Pssm-ID: 466319 [Multi-domain]  Cd Length: 1051  Bit Score: 45.66  E-value: 5.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   1785 AIAVRTKAMKCLSEVVAVDPSIlaRLDMQRGVHGRLMDNSTSVREAAVELLGRF-------VLCRPQLAEqyydmLIERI 1857
Cdd:pfam20168  297 SVAVRIAWVEAAKQILLNHPDL--RSEILEALKDRLLDPDEKVRLAAVKAIGDLdyetllhVVSEKLLKT-----LAERL 369
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   1858 LDTGISVRKRVIKILRDI-------CIEQPtfPKITEMCV----KMIR--RVNDEEgIKKLVNETFQKLWFtPTPHNDKE 1924
Cdd:pfam20168  370 RDKKPSVRKEALKTLAKLynvaygeIEEGD--EEAIEKFGwipnKILHlyYINDPE-IRALVERVLFEYLL-PALLDDEE 445

                   ....
gi 47578105   1925 AMTR 1928
Cdd:pfam20168  446 RVKR 449
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
475-759 1.68e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 43.85  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   475 AEIERIERESAIERERFSKEV--QDKDKPlKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPAlmvsidlhqagrvD 552
Cdd:NF033838  233 AEEEAKRRADAKLKEAVEKNVatSEQDKP-KRRAKRGVLGEPATPDKKENDAKSSDSSVGEETLPS-------------P 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   553 SQASITQDSDSIKKPEEI-KQCNDapvsvlQEDivgslkSTPENHPETPKKKSDPELSKSEMKQSESRLaeskpnenRLV 631
Cdd:NF033838  299 SLKPEKKVAEAEKKVEEAkKKAKD------QKE------EDRRNYPTNTYKTLELEIAESDVKVKEAEL--------ELV 358
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   632 ETKSSENKLETKVETQTEELkqnesrttECKQNESTIVEPKQNENRlsdTKPNDNKQNNGRSETTKSRP-ETPKQKGESR 710
Cdd:NF033838  359 KEEAKEPRNEEKIKQAKAKV--------ESKKAEATRLEKIKTDRK---KAEEEAKRKAAEEDKVKEKPaEQPQPAPAPQ 427
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   711 PETPKQKSDGHPETPK-QKGDGR----------PETPKQKGESRPetPKQKNEGRPETPK 759
Cdd:NF033838  428 PEKPAPKPEKPAEQPKaEKPADQqaeedyarrsEEEYNRLTQQQP--PKTEKPAQPSTPK 485
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
610-919 2.82e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 43.50  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   610 KSEMKQSESRLAESKpneNRLVET--KSSENKLETKVEtQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNK 687
Cdd:PTZ00108 1108 NAELEKKEKELEKLK---NTTPKDmwLEDLDKFEEALE-EQEEVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKK 1183
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   688 qnngrSETTKSRPETPKQkgesrpETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRD 767
Cdd:PTZ00108 1184 -----SSADKSKKASVVG------NSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSK 1252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   768 SGKPSTEKKPEVSKHKQDTKSDSPRLKSerAEALKQRPDGRSvseslrrdhDNKQKSDDRGESERHRGDQSRVRrpetlr 847
Cdd:PTZ00108 1253 SSEDNDEFSSDDLSKEGKPKNAPKRVSA--VQYSPPPPSKRP---------DGESNGGSKPSSPTKKKVKKRLE------ 1315
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47578105   848 sssrnehgIKSDSSKTDKLERKHRHESGDSRERP--SSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDK 919
Cdd:PTZ00108 1316 --------GSLAALKKKKKSEKKTARKKKSKTRVkqASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDD 1381
PRK08581 PRK08581
amidase domain-containing protein;
585-869 2.98e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 43.24  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   585 IVGSLkSTPENHPETPKKKSDPELSKSEMKQSESRlAESKPNENRLVETKSSENKLETkvETQTEELKQNESRTTEckqn 664
Cdd:PRK08581   16 VLPTL-TSPTAYADDPQKDSTAKTTSHDSKKSNDD-ETSKDTSSKDTDKADNNNTSNQ--DNNDKKFSTIDSSTSD---- 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   665 ESTIVEPKQNENRLSDTKP--NDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGES 742
Cdd:PRK08581   88 SNNIIDFIYKNLPQTNINQllTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSK 167
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   743 RPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPrlKSERAEALKQRPDGRSVSESlrRDHDNKQ 822
Cdd:PRK08581  168 QDKADNQKAPSSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDTANQKS--SSKDNQSMSDSALDSILDQY--SEDAKKT 243
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 47578105   823 KSDDRGESERHRGDQSRVRRPEtLRSSSRNEHGIKSDSSKTDKLERK 869
Cdd:PRK08581  244 QKDYASQSKKDKTETSNTKNPQ-LPTQDELKHKSKPAQSFENDVNQS 289
PTZ00112 PTZ00112
origin recognition complex 1 protein; Provisional
588-785 3.30e-03

origin recognition complex 1 protein; Provisional


Pssm-ID: 240274 [Multi-domain]  Cd Length: 1164  Bit Score: 43.05  E-value: 3.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   588 SLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTECKQNEST 667
Cdd:PTZ00112  219 NDKNKEKNKEKDKNIKKDRDGDKQTKRNSEKSKVQNSHFDVRILRSYTKENKKDEKNVVSGIRSSVLLKRKSQCLRKDSY 298
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   668 IVEPKQNENRLSDTKpNDNKQNNGRSETTKSRPETPKQKGESRPetpkqkSDGHPETPKQKGDGRPETPKQKgESRPETP 747
Cdd:PTZ00112  299 VYSNHQKKAKTGDPK-NIIHRNNGSSNSNNDDTSSSNHLGSNRI------SNRNPSSPYKKQTTTKHTNNTK-NNKYNKT 370
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 47578105   748 KQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQD 785
Cdd:PTZ00112  371 KTTQKFNHPLRHHATINKRSSMLPMSEQKGRGASEKSE 408
PTZ00121 PTZ00121
MAEBL; Provisional
563-1201 4.17e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   563 SIKKPEEIKQCNDAPVSVLQEDIVGSLKstpENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLet 642
Cdd:PTZ00121 1025 NIEKIEELTEYGNNDDVLKEKDIIDEDI---DGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGK-- 1099
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   643 kvetqTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKpndnkqnngRSETTKSRPETPKQKGESRPETPKQKSDGHP 722
Cdd:PTZ00121 1100 -----AEEAKKTETGKAEEARKAEEAKKKAEDARKAEEAR---------KAEDARKAEEARKAEDAKRVEIARKAEDARK 1165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   723 -ETPKQKGDGRPETPKQKGES--RPETPKQKNEGRPETPKHRHDNRR---DSGKPSTEKKPEVSKHKQDTKSDSPRLKse 796
Cdd:PTZ00121 1166 aEEARKAEDAKKAEAARKAEEvrKAEELRKAEDARKAEAARKAEEERkaeEARKAEDAKKAEAVKKAEEAKKDAEEAK-- 1243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   797 RAEALKQRPDGRSVSESlRRDHDNKQKSDDRGEsERHRGDQSR----VRRPETLRSSSR----NEHGIKSDSS-KTDKLE 867
Cdd:PTZ00121 1244 KAEEERNNEEIRKFEEA-RMAHFARRQAAIKAE-EARKADELKkaeeKKKADEAKKAEEkkkaDEAKKKAEEAkKADEAK 1321
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   868 RKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAE---FPSY 944
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAE 1401
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   945 LLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEmkgEPKDKVEKIGLVEDLNKGAKpvvvlQKLSLDDVQKliKDREDKS 1024
Cdd:PTZ00121 1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKAD---EAKKKAEEAKKADEAKKKAE-----EAKKAEEAKK--KAEEAKK 1471
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1025 RSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRS----TVNEKPKYAEI-SSDEDNDSDEA 1099
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdeakKAEEAKKADEAkKAEEKKKADEL 1551
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1100 FESSRKRHKKDDDKAWEYEERDRRSSGDHRRS---GHSHEGRRSSGGGRYRNRSPSDSdmEDYSPPPSLSEVARKMKKKE 1176
Cdd:PTZ00121 1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAeeaKKAEEARIEEVMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKAE 1629
                         650       660
                  ....*....|....*....|....*
gi 47578105  1177 KQKKRKAYEPKLTPEEMMDSSTFKR 1201
Cdd:PTZ00121 1630 EEKKKVEQLKKKEAEEKKKAEELKK 1654
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
337-679 6.38e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 42.02  E-value: 6.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   337 EQSEKAAMYDIISSPSKDSTKltlRLSRVRSSDMDQQEDMISGVENSNVSEN--DIPFNVQYPGQTSKTPITPQDINRPL 414
Cdd:PRK14949  473 EASSSLDADNSAVPEQIDSTA---EQSVVNPSVTDTQVDDTSASNNSAADNTvdDNYSAEDTLESNGLDEGDYAQDSAPL 549
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   415 NAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVE------LDA-LAEierieRESAIE 487
Cdd:PRK14949  550 DAYQDDYVAFSSESYNALSDDEQHSANVQSAQSAAEAQPSSQSLSPISAVTTAAASladddiLDAvLAA-----RDSLLS 624
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   488 rERFSKEVQDKD--KPLKKRKQDSYPQEAGGAtggnrPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIK 565
Cdd:PRK14949  625 -DLDALSPKEGDgkKSSADRKPKTPPSRAPPA-----SLSKPASSPDASQTSASFDLDPDFELATHQSVPEAALASGSAP 698
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   566 KPEEIKQCNDAPvsvlqedivgslkstPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLvetkssENKLETKVE 645
Cdd:PRK14949  699 APPPVPDPYDRP---------------PWEEAPEVASANDGPNNAAEGNLSESVEDASNSELQAV------EQQATHQPQ 757
                         330       340       350
                  ....*....|....*....|....*....|....
gi 47578105   646 TQTEelkqnESRTTECKQNESTIVEPKQNENRLS 679
Cdd:PRK14949  758 VQAE-----AQSPASTTALTQTSSEVQDTELNLV 786
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
862-1103 6.99e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 41.96  E-value: 6.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   862 KTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRtegNKSKVDTNKAHPDNKAEF 941
Cdd:PTZ00108 1154 KEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDK---PDNKKSNSSGSDQEDDEE 1230
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105   942 PSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDRE 1021
Cdd:PTZ00108 1231 QKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKV 1310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105  1022 DKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMplceRVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFE 1101
Cdd:PTZ00108 1311 KKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRL----LRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386

                  ..
gi 47578105  1102 SS 1103
Cdd:PTZ00108 1387 DD 1388
DUF612 pfam04747
Protein of unknown function, DUF612; This family includes several uncharacterized proteins ...
468-906 8.73e-03

Protein of unknown function, DUF612; This family includes several uncharacterized proteins from Caenorhabditis elegans.


Pssm-ID: 282585 [Multi-domain]  Cd Length: 511  Bit Score: 41.59  E-value: 8.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    468 EVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALMVSidlhq 547
Cdd:pfam04747  106 EAEAKKRAAQEEEHKQWKAEQERIQKEQEKKEADLKKLQAEKKKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVK----- 180
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    548 agrvdsqaSITQDSDSIKKPEeikqcndapvsvlqedivgslKSTPENHPETPKKKSDP---ELSKSEMKQSESRLAESK 624
Cdd:pfam04747  181 --------KVANDRSAAPAPE---------------------PKTPTNTPAEPAEQVQEitgKKNKKNKKKSESEATAAP 231
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    625 PNENRLVETK---SSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPE 701
Cdd:pfam04747  232 ASVEQVVEQPkvvTEEPHQQAAPQEKKNKKNKRKSESENVPAASETPVEPVVETTPPASENQKKNKKDKKKSESEKVVEE 311
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    702 TPKQKGesrPETPKQKSDGHPE-----TPKQKGDGRP-ETPKQKGESRPETPKQKNEGRPETPkhrhdnrrdsgkPSTEK 775
Cdd:pfam04747  312 PVQAEA---PKSKKPTADDNMDfldfvTAKEEPKDEPaETPAAPVEEVVENVVENVVEKSTTP------------PATEN 376
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47578105    776 KPEVSKHKQdtKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKS-DDRGESERHRGDQSRVRRPETLRSSSRNEH 854
Cdd:pfam04747  377 KKKNKKDKK--KSESEKVTEQPVESAPAPPQVEQVVETTPPASENKKKNkKDKKKSESEKAVEEPVQAAPSSKKPTADDN 454
                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 47578105    855 GIKSD--SSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSD 906
Cdd:pfam04747  455 MDFLDfvTAKPDKSESVEEHIAAPMIVEPAHADEETAAAAEGKKKNKKDKKKKE 508
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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