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Conserved domains on  [gi|158937300|ref|NP_694695|]
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translocation protein SEC63 homolog isoform 1 [Mus musculus]

Protein Classification

DnaJ and SEC63 domain-containing protein( domain architecture ID 11990831)

protein containing domains DnaJ, SEC63, and SEEEED

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEC63 smart00611
Domain of unknown function in Sec63p, Brr2p and other proteins;
209-715 2.46e-73

Domain of unknown function in Sec63p, Brr2p and other proteins;


:

Pssm-ID: 214744  Cd Length: 312  Bit Score: 241.01  E-value: 2.46e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   209 GSWWYRSIRYSGDQiLIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDpqynkdstsRPTDNILIPQLIREIGSINLKK 288
Cdd:smart00611   1 GIWPTDLGRIASYY-YISYTTIRTFNELLKPKMTTKDLLRILSMSSEFD---------QIPVRHEEDLLLEELAEKLPIR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   289 NEPPLTCPYSLKARVLLLSHLARMKIP-ETLEEDQQFMLKKCPALLQEMVNVICQLIImarsreerefraptLASLENCM 367
Cdd:smart00611  71 LENPSLDDPHVKANLLLQAHLSRLKLPsFALESDTVYVLQNAGRLLQAMVDIALERGW--------------LSTALNAL 136

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   368 KLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHkkyKIKTIQDLVSLKESDRHSLLHfLEDEKYEEVMAVLGSFPYVTM 447
Cdd:smart00611 137 NLSQMIIQALWPTDSPLLQLPHLPEEILKRLEKK---KVLSLEDLLELEDEERGELLG-LLDAEGERVYKVLSRLPKLNI 212

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   448 DIKSQVlddedSNNITVGSLVTVLVKLTRQTMaevfekeqsicaaeeqptedgqsdankikakggwqqknkgpkkmpksk 527
Cdd:smart00611 213 EISLEP-----ITRTVLGVEVTLTVDLTWDDE------------------------------------------------ 239

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   528 kkkplkkkpttvplpqakqqkqkqangvvgseaaikeeeddisdkgsdseeeetnrdsqsekedgsdresdreqdekqsk 607
Cdd:smart00611     --------------------------------------------------------------------------------

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   608 ddeaewqelqqsiqrkeralletkskithpvyslyfPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDT-EEVELKFPAP 686
Cdd:smart00611 240 ------------------------------------IHGKQEGWWLVIGDSDGNELLHIERFSLNKKNVsEEVKLDFTAP 283

                          490       500
                   ....*....|....*....|....*....
gi 158937300   687 GKPGNYQYTVFLRSDSYMGLDQIKPLKLE 715
Cdd:smart00611 284 ATEGNYQYTLRLVSDSYLGCDQEYPLSFD 312
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 104-162 7.96e-20

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 83.68  E-value: 7.96e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300  104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG----GDEVMFMRIAKAYAALTDEESRKNWE 162
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpgdpEAEEKFKEINEAYEVLSDPEKRAIYD 63
SEEEED pfam14797
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ...
 564-633 1.01e-05

Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.


:

Pssm-ID: 434218 [Multi-domain]  Cd Length: 111  Bit Score: 45.30  E-value: 1.01e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  564 EEEDDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAEwQELQQSIQRKERALLETKSK 633
Cdd:pfam14797  10 EEEEDSSDSSSDSESESGSESEEEGKEGSSSEDSSEDSSSEQESESGSE-SEKKRTAKRNSKAKGKSDSE 78
 
Name Accession Description Interval E-value
SEC63 smart00611
Domain of unknown function in Sec63p, Brr2p and other proteins;
209-715 2.46e-73

Domain of unknown function in Sec63p, Brr2p and other proteins;


Pssm-ID: 214744  Cd Length: 312  Bit Score: 241.01  E-value: 2.46e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   209 GSWWYRSIRYSGDQiLIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDpqynkdstsRPTDNILIPQLIREIGSINLKK 288
Cdd:smart00611   1 GIWPTDLGRIASYY-YISYTTIRTFNELLKPKMTTKDLLRILSMSSEFD---------QIPVRHEEDLLLEELAEKLPIR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   289 NEPPLTCPYSLKARVLLLSHLARMKIP-ETLEEDQQFMLKKCPALLQEMVNVICQLIImarsreerefraptLASLENCM 367
Cdd:smart00611  71 LENPSLDDPHVKANLLLQAHLSRLKLPsFALESDTVYVLQNAGRLLQAMVDIALERGW--------------LSTALNAL 136

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   368 KLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHkkyKIKTIQDLVSLKESDRHSLLHfLEDEKYEEVMAVLGSFPYVTM 447
Cdd:smart00611 137 NLSQMIIQALWPTDSPLLQLPHLPEEILKRLEKK---KVLSLEDLLELEDEERGELLG-LLDAEGERVYKVLSRLPKLNI 212

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   448 DIKSQVlddedSNNITVGSLVTVLVKLTRQTMaevfekeqsicaaeeqptedgqsdankikakggwqqknkgpkkmpksk 527
Cdd:smart00611 213 EISLEP-----ITRTVLGVEVTLTVDLTWDDE------------------------------------------------ 239

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   528 kkkplkkkpttvplpqakqqkqkqangvvgseaaikeeeddisdkgsdseeeetnrdsqsekedgsdresdreqdekqsk 607
Cdd:smart00611     --------------------------------------------------------------------------------

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   608 ddeaewqelqqsiqrkeralletkskithpvyslyfPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDT-EEVELKFPAP 686
Cdd:smart00611 240 ------------------------------------IHGKQEGWWLVIGDSDGNELLHIERFSLNKKNVsEEVKLDFTAP 283

                          490       500
                   ....*....|....*....|....*....
gi 158937300   687 GKPGNYQYTVFLRSDSYMGLDQIKPLKLE 715
Cdd:smart00611 284 ATEGNYQYTLRLVSDSYLGCDQEYPLSFD 312
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 104-162 7.96e-20

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 83.68  E-value: 7.96e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300  104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG----GDEVMFMRIAKAYAALTDEESRKNWE 162
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpgdpEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
104-157 3.33e-17

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 76.12  E-value: 3.33e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 158937300   104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD-----EVMFMRIAKAYAALTDEES 157
Cdd:smart00271   2 DYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkeeaEEKFKEINEAYEVLSDPEK 60
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 104-167 2.25e-16

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 76.66  E-value: 2.25e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRKNWEEFGNP 167
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdpeaEEKFKEINEAYEVLSDPEKRAAYDRFGHA 68
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 94-165 2.36e-16

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 82.18  E-value: 2.36e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 158937300  94 SKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PTZ00037  19 GRRKREVDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDPEKFKEISRAYEVLSDPEKRKIYDEYG 90
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 104-154 3.39e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 72.96  E-value: 3.39e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTD 154
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdpeaEEKFKEINEAYEVLSD 55
Sec63 pfam02889
Sec63 Brl domain; This domain (also known as the Brl domain) is required for assembly of ...
 225-477 1.12e-13

Sec63 Brl domain; This domain (also known as the Brl domain) is required for assembly of functional endoplasmic reticulum translocons.


Pssm-ID: 460740  Cd Length: 307  Bit Score: 72.62  E-value: 1.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  225 IRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDpqynkdstsrptdniLIPqlIREIGSINLKK-NEPpltCPYSL---- 299
Cdd:pfam02889  13 ISYETIETFNQSLKPNTTLADLLRILSSASEFE---------------QIP--VRQEEKKELKKlLEK---VPIPVkgdi 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  300 -----KARVLLLSHLARMKIPE-TLEEDQQFMLKKCPALLQEMVnvicqLIIMARSReerefraptLASLENCMKLSQMA 373
Cdd:pfam02889  73 edphaKVNILLQAYISRLKLPGfALVSDMNYILQNAGRILRALF-----EILLSKGW---------LSAALTALDLCKMI 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  374 VQGLQQFKSPLLQLPHIEEDNLRRvsnHKKYKIKTIQDLvsLKESDRHSLLHFLEDEKY-EEVMAVLGSFPYVTMDIKSQ 452
Cdd:pfam02889 139 EQRMWDSDSPLRQFPGIPPELIKK---LEKKGVESVRDI--LELDDAEELGELIRNPKMgKDIAQFVNRFPKIEIEAEVQ 213

                         250       260
                  ....*....|....*....|....*
gi 158937300  453 VLddedsnnitVGSLVTVLVKLTRQ 477
Cdd:pfam02889 214 PI---------TRSVLRVEVTITPD 229
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 106-176 1.34e-13

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 73.02  E-value: 1.34e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300  106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKNWEEFGNpDGPQATSFG 176
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDRNkdkEAEEKFKEINEAYEVLSDPEKRAQYDQFGH-AGFNGGGGG 75
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
106-165 7.28e-10

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 61.76  E-value: 7.28e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKApdaAEIFAEINEAYEVLSNPEKRANYDKYG 70
SEEEED pfam14797
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ...
 564-633 1.01e-05

Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.


Pssm-ID: 434218 [Multi-domain]  Cd Length: 111  Bit Score: 45.30  E-value: 1.01e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  564 EEEDDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAEwQELQQSIQRKERALLETKSK 633
Cdd:pfam14797  10 EEEEDSSDSSSDSESESGSESEEEGKEGSSSEDSSEDSSSEQESESGSE-SEKKRTAKRNSKAKGKSDSE 78
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 450-661 2.40e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   450 KSQVLDDEDSNNITVGSLVTVlvkltrqtmaEVFEKEQSICAAEEQPTEDGQsDANKIKAKGGWQQKNKGPKKMPKSKKK 529
Cdd:TIGR00927  737 EGEEVEDEGEGEAEGKHEVET----------EGDRKETEHEGETEAEGKEDE-DEGEIQAGEDGEMKGDEGAEGKVEHEG 805

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   530 KPLKKKPTTVPLPQAKQQKQKQANGVVGSEAAIKEEEDDISD--KGSDSEEEETNRDSQSEKEDgsDRESDREQDEKQSK 607
Cdd:TIGR00927  806 ETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQdeKGVDGGGGSDGGDSEEEEEE--EEEEEEEEEEEEEE 883

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 158937300   608 DDEAEWQELQQSIQRKERallETKSKITHPVYSLYFPeekqewWWLYIADRKEQ 661
Cdd:TIGR00927  884 EEEEEENEEPLSLEWPET---RQKQAIYLFLLPIVFP------LWLTVPDVRRQ 928
 
Name Accession Description Interval E-value
SEC63 smart00611
Domain of unknown function in Sec63p, Brr2p and other proteins;
209-715 2.46e-73

Domain of unknown function in Sec63p, Brr2p and other proteins;


Pssm-ID: 214744  Cd Length: 312  Bit Score: 241.01  E-value: 2.46e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   209 GSWWYRSIRYSGDQiLIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDpqynkdstsRPTDNILIPQLIREIGSINLKK 288
Cdd:smart00611   1 GIWPTDLGRIASYY-YISYTTIRTFNELLKPKMTTKDLLRILSMSSEFD---------QIPVRHEEDLLLEELAEKLPIR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   289 NEPPLTCPYSLKARVLLLSHLARMKIP-ETLEEDQQFMLKKCPALLQEMVNVICQLIImarsreerefraptLASLENCM 367
Cdd:smart00611  71 LENPSLDDPHVKANLLLQAHLSRLKLPsFALESDTVYVLQNAGRLLQAMVDIALERGW--------------LSTALNAL 136

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   368 KLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHkkyKIKTIQDLVSLKESDRHSLLHfLEDEKYEEVMAVLGSFPYVTM 447
Cdd:smart00611 137 NLSQMIIQALWPTDSPLLQLPHLPEEILKRLEKK---KVLSLEDLLELEDEERGELLG-LLDAEGERVYKVLSRLPKLNI 212

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   448 DIKSQVlddedSNNITVGSLVTVLVKLTRQTMaevfekeqsicaaeeqptedgqsdankikakggwqqknkgpkkmpksk 527
Cdd:smart00611 213 EISLEP-----ITRTVLGVEVTLTVDLTWDDE------------------------------------------------ 239

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   528 kkkplkkkpttvplpqakqqkqkqangvvgseaaikeeeddisdkgsdseeeetnrdsqsekedgsdresdreqdekqsk 607
Cdd:smart00611     --------------------------------------------------------------------------------

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   608 ddeaewqelqqsiqrkeralletkskithpvyslyfPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDT-EEVELKFPAP 686
Cdd:smart00611 240 ------------------------------------IHGKQEGWWLVIGDSDGNELLHIERFSLNKKNVsEEVKLDFTAP 283

                          490       500
                   ....*....|....*....|....*....
gi 158937300   687 GKPGNYQYTVFLRSDSYMGLDQIKPLKLE 715
Cdd:smart00611 284 ATEGNYQYTLRLVSDSYLGCDQEYPLSFD 312
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 104-162 7.96e-20

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 83.68  E-value: 7.96e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300  104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG----GDEVMFMRIAKAYAALTDEESRKNWE 162
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNpgdpEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ smart00271
DnaJ molecular chaperone homology domain;
104-157 3.33e-17

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 76.12  E-value: 3.33e-17
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 158937300   104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD-----EVMFMRIAKAYAALTDEES 157
Cdd:smart00271   2 DYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGdkeeaEEKFKEINEAYEVLSDPEK 60
Sec63 smart00973
Sec63 Brl domain; This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl ...
 238-476 2.06e-16

Sec63 Brl domain; This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl domain) protein in which it was found. This protein is required for assembly of functional endoplasmic reticulum translocons. Other yeast proteins containing this domain include pre-mRNA splicing helicase BRR2, HFM1 protein and putative helicases.


Pssm-ID: 214946  Cd Length: 314  Bit Score: 80.87  E-value: 2.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   238 TRNMDMKRLIMVLAGASEFDpqynkdstsrptdniLIPQLIREIGSINLKKNEPPLTCP------YSLKARVLLLSHLAR 311
Cdd:smart00973  26 KPTTTLKDILEILSRASEFK---------------EIPVRHNEKKELNELNKRVPIPVKegiidsPHAKVNLLLQAHLSR 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   312 MKIPE-TLEEDQQFMLKKCPALLQEMVNVICQLIimarsreerefrapTLASLENCMKLSQMAVQGL-QQFKSPLLQLPH 389
Cdd:smart00973  91 LPLPDfDLVSDLKYILQNAPRILRALVDIALSKG--------------WLRTALNALDLSQMVVQRLwEDSDSPLKQLPH 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   390 IEEDNLRRVsNHKKYKIKTIQDLVSLKESDRHSLLHFLEDEKyEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVT 469
Cdd:smart00973 157 FLIEDVYDK-LELKDGSRSFELLLDMNAAELGEFLNRLPPNG-RLIYELLRRFPKIEVEAEVLPITRDLTLRVELEITPV 234


                   ....*..
gi 158937300   470 VLVKLTR 476
Cdd:smart00973 235 FAWDLPR 241
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 104-167 2.25e-16

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 76.66  E-value: 2.25e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRKNWEEFGNP 167
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGdpeaEEKFKEINEAYEVLSDPEKRAAYDRFGHA 68
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 94-165 2.36e-16

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 82.18  E-value: 2.36e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 158937300  94 SKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PTZ00037  19 GRRKREVDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDPEKFKEISRAYEVLSDPEKRKIYDEYG 90
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 104-154 3.39e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 72.96  E-value: 3.39e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTD 154
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDdpeaEEKFKEINEAYEVLSD 55
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
104-159 1.66e-14

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 69.36  E-value: 1.66e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGG-----DEVMFMRIAKAYAALTDEESRK 159
Cdd:COG2214    6 DHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGelkalAEELFQRLNEAYEVLSDPERRA 66
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 104-159 2.09e-14

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 68.10  E-value: 2.09e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRK 159
Cdd:COG5407    1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGdpkaEERFKEINEAYELLSDAEKRA 60
PRK14280 PRK14280
molecular chaperone DnaJ;
98-176 8.40e-14

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 73.60  E-value: 8.40e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  98 REYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPD----KGGDEvMFMRIAKAYAALTDEESRKNWEEFGNpDGPQAT 173
Cdd:PRK14280   4 RDY-----YEVLGVSKSASKDEIKKAYRKLSKKYHPDinkeEGADE-KFKEISEAYEVLSDDQKRAQYDQFGH-AGPNQG 76


                 ...
gi 158937300 174 sFG 176
Cdd:PRK14280  77 -FG 78
Sec63 pfam02889
Sec63 Brl domain; This domain (also known as the Brl domain) is required for assembly of ...
 225-477 1.12e-13

Sec63 Brl domain; This domain (also known as the Brl domain) is required for assembly of functional endoplasmic reticulum translocons.


Pssm-ID: 460740  Cd Length: 307  Bit Score: 72.62  E-value: 1.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  225 IRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDpqynkdstsrptdniLIPqlIREIGSINLKK-NEPpltCPYSL---- 299
Cdd:pfam02889  13 ISYETIETFNQSLKPNTTLADLLRILSSASEFE---------------QIP--VRQEEKKELKKlLEK---VPIPVkgdi 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  300 -----KARVLLLSHLARMKIPE-TLEEDQQFMLKKCPALLQEMVnvicqLIIMARSReerefraptLASLENCMKLSQMA 373
Cdd:pfam02889  73 edphaKVNILLQAYISRLKLPGfALVSDMNYILQNAGRILRALF-----EILLSKGW---------LSAALTALDLCKMI 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  374 VQGLQQFKSPLLQLPHIEEDNLRRvsnHKKYKIKTIQDLvsLKESDRHSLLHFLEDEKY-EEVMAVLGSFPYVTMDIKSQ 452
Cdd:pfam02889 139 EQRMWDSDSPLRQFPGIPPELIKK---LEKKGVESVRDI--LELDDAEELGELIRNPKMgKDIAQFVNRFPKIEIEAEVQ 213

                         250       260
                  ....*....|....*....|....*
gi 158937300  453 VLddedsnnitVGSLVTVLVKLTRQ 477
Cdd:pfam02889 214 PI---------TRSVLRVEVTITPD 229
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 96-166 1.33e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 73.34  E-value: 1.33e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300  96 TDREYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD---EVMFMRIAKAYAALTDEESRKNWEEFGN 166
Cdd:PRK14298   3 TTRDY-----YEILGLSKDASVEDIKKAYRKLAMKYHPDKNKEpdaEEKFKEISEAYAVLSDAEKRAQYDRFGH 71
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 106-176 1.34e-13

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 73.02  E-value: 1.34e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300  106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKNWEEFGNpDGPQATSFG 176
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDRNkdkEAEEKFKEINEAYEVLSDPEKRAQYDQFGH-AGFNGGGGG 75
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 98-166 6.72e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 71.01  E-value: 6.72e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 158937300  98 REYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFGN 166
Cdd:PRK14283   5 RDY-----YEVLGVDRNADKKEIKKAYRKLARKYHPDvseEEGAEEKFKEISEAYAVLSDDEKRQRYDQFGH 71
PRK14297 PRK14297
molecular chaperone DnaJ;
106-176 1.76e-12

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 69.81  E-value: 1.76e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFG 176
Cdd:PRK14297   7 YEVLGLEKGASDDEIKKAFRKLAIKYHPDKNkGNkeaEEKFKEINEAYQVLSDPQKKAQYDQFGTADFNGAGGFG 81
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 106-176 5.17e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 68.29  E-value: 5.17e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFG----NPDGPQATSFG 176
Cdd:PRK14277   8 YEILGVDRNATEEEIKKAYRRLAKKYHPDLNpGDkeaEQKFKEINEAYEILSDPQKRAQYDQFGhaafDPGGFGQGGFG 86
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 106-176 3.98e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 65.63  E-value: 3.98e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFGNpDGPQATSFG 176
Cdd:PRK14284   4 YTILGVSKTASPEEIKKAYRKLAVKYHPDKNpGDaeaEKRFKEVSEAYEVLSDAQKRESYDRYGK-DGPFAGAGG 77
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 106-170 4.53e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 65.30  E-value: 4.53e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGP 170
Cdd:PRK14292   5 YELLGVSRTASADEIKSAYRKLALKYHPDRNkekGAAEKFAQINEAYAVLSDAEKRAHYDRFGTAPGA 72
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 106-165 8.93e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 64.40  E-value: 8.93e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDK-GGD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK10767   7 YEVLGVSRNASEDEIKKAYRKLAMKYHPDRnPGDkeaEEKFKEIKEAYEVLSDPQKRAAYDQYG 70
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 96-176 1.09e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 64.44  E-value: 1.09e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  96 TDREYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRKNWEEFGNPD-GP 170
Cdd:PRK14281   1 MKRDY-----YEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDnkeaEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGvGS 75


                 ....*.
gi 158937300 171 QATSFG 176
Cdd:PRK14281  76 SAASGG 81
PRK14295 PRK14295
molecular chaperone DnaJ;
98-166 2.02e-10

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 63.33  E-value: 2.02e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 158937300  98 REYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPD--KG--GDEVMFMRIAKAYAALTDEESRKNWEE----FGN 166
Cdd:PRK14295   4 KDYIEKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDanKGdaKAEERFKEISEAYDVLSDEKKRKEYDEarslFGN 80
PRK14289 PRK14289
molecular chaperone DnaJ;
96-166 3.96e-10

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 62.54  E-value: 3.96e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300  96 TDREYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFGN 166
Cdd:PRK14289   3 EKRDY-----YEVLGVSKTATVDEIKKAYRKKAIQYHPDKNpGDkeaEEKFKEAAEAYDVLSDPDKRSRYDQFGH 72
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 101-176 4.40e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 62.41  E-value: 4.40e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 158937300 101 QEYnpYEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQAtsFG 176
Cdd:PRK14276   4 TEY--YDRLGVSKDASQDEIKKAYRKLSKKYHPDinkEPGAEEKYKEVQEAYETLSDPQKRAAYDQYGAAGANGG--FG 78
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 106-176 5.47e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 61.70  E-value: 5.47e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFGNpDGPQATSFG 176
Cdd:PRK14294   7 YEILGVTRDASEEEIKKSYRKLAMKYHPDRNpGDkeaEELFKEAAEAYEVLSDPKKRGIYDQYGH-EGLSGTGFS 80
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
106-165 7.28e-10

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 61.76  E-value: 7.28e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKApdaAEIFAEINEAYEVLSNPEKRANYDKYG 70
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 106-165 7.35e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 61.71  E-value: 7.35e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK14291   6 YEILGVSRNATQEEIKKAYRRLARKYHPDfnkNPEAEEKFKEINEAYQVLSDPEKRKLYDQFG 68
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 106-176 1.07e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 61.18  E-value: 1.07e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPD--KGGD-EVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQAtsFG 176
Cdd:PRK14287   7 YEVLGVDRNASVDEVKKAYRKLARKYHPDvnKAPDaEDKFKEVKEAYDTLSDPQKKAHYDQFGHTDPNQG--FG 78
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
104-151 1.29e-09

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 55.19  E-value: 1.29e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 158937300 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDK--GGDEVMFMRIAKAYAA 151
Cdd:COG1076    5 DAFELLGLPPDADDAELKRAYRKLQREHHPDRlaAGLPEEEQRLALQKAA 54
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 106-166 1.63e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 60.39  E-value: 1.63e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRKNWEEFGN 166
Cdd:PRK14285   6 YEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGnkeaESIFKEATEAYEVLIDDNKRAQYDRFGH 70
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 106-165 4.42e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 58.99  E-value: 4.42e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD----EVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK14301   7 YEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDnpeaEQKFKEAAEAYEVLRDAEKRARYDRFG 70
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 96-165 7.19e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 58.46  E-value: 7.19e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158937300  96 TDREYqeynpYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK14286   2 SERSY-----YDILGVSKSANDEEIKSAYRKLAIKYHPDKNkGNkesEEKFKEATEAYEILRDPKKRQAYDQFG 70
PRK14293 PRK14293
molecular chaperone DnaJ;
106-165 3.46e-08

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 56.15  E-value: 3.46e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK14293   6 YEILGVSRDADKDELKRAYRRLARKYHPDvnkEPGAEDRFKEINRAYEVLSDPETRARYDQFG 68
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 106-168 4.73e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 55.71  E-value: 4.73e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPD-----KGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPD 168
Cdd:PRK14290   6 YKILGVDRNASQEDIKKAFRELAKKWHPDlhpgnKAEAEEKFKEISEAYEVLSDPQKRRQYDQTGTVD 73
PRK14279 PRK14279
molecular chaperone DnaJ;
96-164 5.38e-08

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 55.89  E-value: 5.38e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300  96 TDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG-GD---EVMFMRIAKAYAALTDEESRKNWEEF 164
Cdd:PRK14279   2 AQREWVEKDFYKELGVSSDASAEEIKKAYRKLARELHPDANpGDpaaEERFKAVSEAHDVLSDPAKRKEYDET 74
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 100-169 8.79e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 54.56  E-value: 8.79e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300 100 YQEYnpYEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDG 169
Cdd:PRK14299   3 YKDY--YAILGVPKNASQDEIKKAFKKLARKYHPDvnkSPGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTAA 73
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 106-167 1.96e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 53.90  E-value: 1.96e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVM---FMRIAKAYAALTDEESRKNWEEFGNP 167
Cdd:PRK14278   6 YGLLGVSRNASDAEIKRAYRKLARELHPDVNPDEEAqekFKEISVAYEVLSDPEKRRIVDLGGDP 70
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 106-178 1.86e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 50.72  E-value: 1.86e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPD---KGGDEVMFMRIAKAYAALTDEESRKNWEEFGNP--DGPQATSFGIA 178
Cdd:PRK14296   7 YEVLGVSKTASEQEIRQAYRKLAKQYHPDlnkSPDAHDKMVEINEAADVLLDKDKRKQYDQFGHAafDGSSGFSSNFG 84
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 101-166 1.94e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 50.78  E-value: 1.94e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 158937300 101 QEYnpYEVLNLDPGATVAEIKKQYRLLSLKYHPDK---GGDEVMFMRIAKAYAALTDEESRKNWEEFGN 166
Cdd:PRK14300   3 QDY--YQILGVSKTASQADLKKAYLKLAKQYHPDTtdaKDAEKKFKEINAAYDVLKDEQKRAAYDRFGH 69
PRK14288 PRK14288
molecular chaperone DnaJ;
102-172 5.61e-06

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 49.30  E-value: 5.61e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158937300 102 EYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDK-GGD---EVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQA 172
Cdd:PRK14288   2 ELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRnAGDkeaEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQA 76
SEEEED pfam14797
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ...
 564-633 1.01e-05

Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.


Pssm-ID: 434218 [Multi-domain]  Cd Length: 111  Bit Score: 45.30  E-value: 1.01e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300  564 EEEDDISDKGSDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAEwQELQQSIQRKERALLETKSK 633
Cdd:pfam14797  10 EEEEDSSDSSSDSESESGSESEEEGKEGSSSEDSSEDSSSEQESESGSE-SEKKRTAKRNSKAKGKSDSE 78
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 98-165 2.41e-05

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 47.48  E-value: 2.41e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 158937300  98 REYQEYnpYEVLNLDPGATVAEIKKQYRLLSLKYHPD-----KGGDEVMFMRIAKAYAALTDEESRKNWEEFG 165
Cdd:PRK14282   1 REKKDY--YEILGVSRNATQEEIKRAYKRLVKEWHPDrhpenRKEAEQKFKEIQEAYEVLSDPQKRAMYDRFG 71
PHA03102 PHA03102
Small T antigen; Reviewed
 107-184 5.12e-05

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 44.28  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300 107 EVLNLDPGA--TVAEIKKQYRLLSLKYHPDKGGDEVMFMRI---------AKAYAALTDEESRKNWEEFGNPDGPQATSF 175
Cdd:PHA03102   9 DLLGLPRSAwgNLPLMRKAYLRKCLEFHPDKGGDEEKMKELntlykkfreSVKSLRDLDGEEDSSSEEEDVPSGYVGATF 88


                 ....*....
gi 158937300 176 GIALPAWIV 184
Cdd:PHA03102  89 GDRVNALYC 97
SEEEED pfam14797
Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly ...
 574-612 1.29e-04

Serine-rich region of AP3B1, clathrin-adaptor complex; This short low-complexity, highly serine-rich region lies on clathrin-adaptor complex 3 beta-1 subunit proteins, between family Adaptin_N, pfam01602 and a C-terminal domain, AP3B1_C,pfam14796.


Pssm-ID: 434218 [Multi-domain]  Cd Length: 111  Bit Score: 41.84  E-value: 1.29e-04
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 158937300  574 SDSEEEETNRDSQSEKEDGSDRESDREQDEKQSKDDEAE 612
Cdd:pfam14797   7 SESEEEEDSSDSSSDSESESGSESEEEGKEGSSSEDSSE 45
PHA02624 PHA02624
large T antigen; Provisional
 107-139 3.30e-04

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 44.20  E-value: 3.30e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 158937300 107 EVLNLDPGA--TVAEIKKQYRLLSLKYHPDKGGDE 139
Cdd:PHA02624  15 DLLGLPMAAwgNLPLMRKAYLRKCKEYHPDKGGDE 49
djlA PRK09430
co-chaperone DjlA;
106-147 1.62e-03

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 40.95  E-value: 1.62e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDK----GGDEVMfMRIAK 147
Cdd:PRK09430 203 YKVLGVSESDDDQEIKRAYRKLMSEHHPDKlvakGLPPEM-MEMAK 247
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 450-661 2.40e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 2.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   450 KSQVLDDEDSNNITVGSLVTVlvkltrqtmaEVFEKEQSICAAEEQPTEDGQsDANKIKAKGGWQQKNKGPKKMPKSKKK 529
Cdd:TIGR00927  737 EGEEVEDEGEGEAEGKHEVET----------EGDRKETEHEGETEAEGKEDE-DEGEIQAGEDGEMKGDEGAEGKVEHEG 805

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158937300   530 KPLKKKPTTVPLPQAKQQKQKQANGVVGSEAAIKEEEDDISD--KGSDSEEEETNRDSQSEKEDgsDRESDREQDEKQSK 607
Cdd:TIGR00927  806 ETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQdeKGVDGGGGSDGGDSEEEEEE--EEEEEEEEEEEEEE 883

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 158937300   608 DDEAEWQELQQSIQRKERallETKSKITHPVYSLYFPeekqewWWLYIADRKEQ 661
Cdd:TIGR00927  884 EEEEEENEEPLSLEWPET---RQKQAIYLFLLPIVFP------LWLTVPDVRRQ 928
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 106-137 4.33e-03

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 37.91  E-value: 4.33e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 158937300 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGG 137
Cdd:PTZ00100  68 YKILNISPTASKERIREAHKQLMLRNHPDNGG 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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