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Conserved domains on  [gi|47080103|ref|NP_998733|]
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zinc transporter ZIP3 isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Zip super family cl00437
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
 5-69 4.69e-06

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


The actual alignment was detected with superfamily member pfam02535:

Pssm-ID: 444905 [Multi-domain]  Cd Length: 325  Bit Score: 43.13  E-value: 4.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47080103     5 LVAKILCMVGVFFFMLLGSLLPVKIIEtdFEKAHRSKKILSLCNTFGGGVFLATCFNALLPAVRE 69
Cdd:pfam02535   1 LLLKIYAIFAILIISLIGGLLPLLVPK--ISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALE 63
 
Name Accession Description Interval E-value
Zip pfam02535
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
 5-69 4.69e-06

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


Pssm-ID: 396884 [Multi-domain]  Cd Length: 325  Bit Score: 43.13  E-value: 4.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47080103     5 LVAKILCMVGVFFFMLLGSLLPVKIIEtdFEKAHRSKKILSLCNTFGGGVFLATCFNALLPAVRE 69
Cdd:pfam02535   1 LLLKIYAIFAILIISLIGGLLPLLVPK--ISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALE 63
 
Name Accession Description Interval E-value
Zip pfam02535
ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative ...
 5-69 4.69e-06

ZIP Zinc transporter; The ZIP family consists of zinc transport proteins and many putative metal transporters. The main contribution to this family is from the Arabidopsis thaliana ZIP protein family these proteins are responsible for zinc uptake in the plant. Also found within this family are C. elegans proteins of unknown function which are annotated as being similar to human growth arrest inducible gene product, although this protein in not found within this family.


Pssm-ID: 396884 [Multi-domain]  Cd Length: 325  Bit Score: 43.13  E-value: 4.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47080103     5 LVAKILCMVGVFFFMLLGSLLPVKIIEtdFEKAHRSKKILSLCNTFGGGVFLATCFNALLPAVRE 69
Cdd:pfam02535   1 LLLKIYAIFAILIISLIGGLLPLLVPK--ISKLRPSSKLLSLLLAFASGVLLGTAFLHLLPEALE 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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