|
Name |
Accession |
Description |
Interval |
E-value |
| ZnMc_ADAMTS_like |
cd04273 |
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) ... |
217-411 |
9.53e-72 |
|
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that combine ADAM-like metalloproteinases with thrombospondin type-1 repeats. ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteinases are inhibited by TIMPs (tissue inhibitors of metalloproteinases), and they play roles in coagulation, angiogenesis, development and progression of arthritis. They hydrolyze the von Willebrand factor precursor and various components of the extracellular matrix.
:
Pssm-ID: 239801 Cd Length: 207 Bit Score: 239.83 E-value: 9.53e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFD-YHGDDTEFYIFTILNQVAGLFRDKTLSADLRLLVTSITIFTAPQSNLDLTDELSHSLKNFCEWQ 295
Cdd:cd04273 1 RYVETLVVADSKMVEfHHGEDLEHYILTLMNIVASLYKDPSLGNSINIVVVRLIVLEDEESGLLISGNAQKSLKSFCRWQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 296 KDEKS---------DISILLTRRDLEIG-GNDAVTGKSkDIGGACDPSRRCIIAQDHGpSGTIFTLAHEIGHSLGIYHDD 365
Cdd:cd04273 81 KKLNPpndsdpehhDHAILLTRQDICRSnGNCDTLGLA-PVGGMCSPSRSCSINEDTG-LSSAFTIAHELGHVLGMPHDG 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 47551295 366 SESGCA---NNKNIMATDNSGGSEAFQWSLCSNKDLLQFLSTSDSVCLD 411
Cdd:cd04273 159 DGNSCGpegKDGHIMSPTLGANTGPFTWSKCSRRYLTSFLDTGDGNCLL 207
|
|
| Pep_M12B_propep |
pfam01562 |
Reprolysin family propeptide; This region is the propeptide for members of peptidase family ... |
56-184 |
3.34e-20 |
|
Reprolysin family propeptide; This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
:
Pssm-ID: 460254 Cd Length: 128 Bit Score: 88.91 E-value: 3.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 56 VKPVRL-GTRHQRSV-EERSVTSTSEYSVEGFDHVFHIQLKQTMDLFNAGLLVKRINENGQVRIEQP--ETGCYHQGHVK 131
Cdd:pfam01562 3 VIPVRLdPSRRRRSLaSESTYLDTLSYRLAAFGKKFHLHLTPNRLLLAPGFTVTYYLDGGTGVESPPvqTDHCYYQGHVE 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 132 DSEHtSSVSLSTCNGLVGMIRTPEGDFVLKPLredhivkMKSSENEVP-THIMY 184
Cdd:pfam01562 83 GHPD-SSVALSTCSGLRGFIRTENEEYLIEPL-------EKYSREEGGhPHVVY 128
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1185-1287 |
4.45e-19 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 85.16 E-value: 4.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1185 GSTTYTLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSANSL---CDEVAlPYVY 1259
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEssPNCSYDYLEIYDGPSTSSPLLgrfCGSTL-PPPI 85
|
90 100
....*....|....*....|....*...
gi 47551295 1260 ESTSPMLEVLFLTDATVNMRGFSATYQA 1287
Cdd:cd00041 86 ISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1353-1466 |
3.92e-17 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 79.76 E-value: 3.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1353 CGENILRLAPGLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTIGFLvFINGGVPCQEgDSVTIQD--TSSGEPVISLC- 1429
Cdd:cd00041 1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDF-DLESSPNCSY-DYLEIYDgpSTSSPLLGRFCg 78
|
90 100 110
....*....|....*....|....*....|....*..
gi 47551295 1430 QSTPADIISLTNEVTLTFVSDGNpaPQGTGFTLQYFS 1466
Cdd:cd00041 79 STLPPPIISSGNSLTVRFRSDSS--VTGRGFKATYSA 113
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3355-3434 |
4.08e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3355 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3433
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3434 V 3434
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3193-3272 |
4.12e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3193 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3271
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3272 V 3272
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2788-2867 |
4.24e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2788 DNEIPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 2866
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2867 V 2867
Cdd:pfam02494 81 V 81
|
|
| ADAMTS_CR_2 |
pfam17771 |
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS ... |
428-499 |
5.56e-17 |
|
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS peptidases (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) which is closely related to the ADAM family (pfam08516). Members of the ADAM-TS family have been implicated in a range of diseases. For instance, members of this family have been found to participate directly in processes in the central nervous system (CNS) such as the regulation of brain plasticity.
:
Pssm-ID: 465496 Cd Length: 68 Bit Score: 77.77 E-value: 5.56e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47551295 428 PGHYYDALKQCQMTFGSEATVADGYiySQDMCLELQCRVPGRSEDITNHTPALDGTKCGTGRgvMCVHGQCL 499
Cdd:pfam17771 1 PGQLYSADEQCRLIFGPGSTFCPNG--DEDVCSKLWCSNPGGSTCTTKNLPAADGTPCGNKK--WCLNGKCV 68
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3031-3110 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3031 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3109
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3110 V 3110
Cdd:pfam02494 81 V 81
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3274-3353 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3274 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3352
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3353 V 3353
Cdd:pfam02494 81 V 81
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2869-2948 |
1.59e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2869 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 2947
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2948 V 2948
Cdd:pfam02494 81 V 81
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3112-3191 |
2.65e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 76.27 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3112 DNENPVISgCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3190
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3191 V 3191
Cdd:pfam02494 81 V 81
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2950-3029 |
1.36e-15 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 74.35 E-value: 1.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2950 DNEIPVISgCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 3028
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3029 V 3029
Cdd:pfam02494 81 V 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2542-2647 |
6.09e-15 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
:
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 73.19 E-value: 6.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2542 YISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDLILAEDPyfaLDQAYCGNQENFL 2621
Cdd:smart00042 2 TITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSD---NC-EYDYVEIYDGPSASSP---LLGRFCGSEAPPP 74
|
90 100
....*....|....*....|....*..
gi 47551295 2622 WFSTQ-NLAVLSFLSNDEGVYPGYQIY 2647
Cdd:smart00042 75 VISSSsNSLTLTFVSDSSVQKRGFSAR 101
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2014-2118 |
6.43e-15 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 73.60 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2014 LTEEGIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLgRFELgLTNGDCEAgDYIELTDENWEY--LDATYCGGSLPP 2091
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFE-DFDL-ESSPNCSY-DYLEIYDGPSTSspLLGRFCGSTLPP 83
|
90 100
....*....|....*....|....*..
gi 47551295 2092 VWRSRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:cd00041 84 PIISSGNSLTVRFRSDSSVTGRGFKAT 110
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3436-3515 |
1.07e-14 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 71.65 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISgCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3514
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3515 V 3515
Cdd:pfam02494 81 V 81
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1474-1583 |
3.04e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 68.59 E-value: 3.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1474 CGGNITTSGQ-PIYSPNYPANYDDNVTCVTDITNDEGC-ISIEFLMMDIDNgdyvNDTCMEDSLTITD---YNNPSLSRT 1548
Cdd:cd00041 1 CGGTLTASTSgTISSPNYPNNYPNNLNCVWTIEAPPGYrIRLTFEDFDLES----SPNCSYDYLEIYDgpsTSSPLLGRF 76
|
90 100 110
....*....|....*....|....*....|....*
gi 47551295 1549 nCGDSTPEsPWLSASGNVKVSFTSNGANSSQGYIA 1583
Cdd:cd00041 77 -CGSTLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1827-1941 |
8.28e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 67.44 E-value: 8.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1827 CSEDVT--RPGVIVSPGFgtedhygnYDGYDNNLNCIYNITNPNSTEcITVSFISFDLgQPSENCS-DYVQITDTEGGVD 1903
Cdd:cd00041 1 CGGTLTasTSGTISSPNY--------PNNYPNNLNCVWTIEAPPGYR-IRLTFEDFDL-ESSPNCSyDYLEIYDGPSTSS 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 47551295 1904 FL---YCGlpeNTTAPVFYSRSANVEVVFRTGEDERNDGFE 1941
Cdd:cd00041 71 PLlgrFCG---STLPPPIISSGNSLTVRFRSDSSVTGRGFK 108
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
996-1051 |
1.53e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.78 E-value: 1.53e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 996 WRIGAWSPCSVSCGNGVETRVVYCVEsEDSNVIIPSTSCDPAAEPASVQICNPGDC 1051
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQ-KGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3517-3595 |
1.66e-12 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 65.49 E-value: 1.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3517 DNENPVISgCPSDQNVAISIGNA-AVVTWTPPTATDNSGNQTLTSTNN-PGDDFTIGNNTVTYSASDDAGNTEYCTFFVV 3594
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTStVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3595 V 3595
Cdd:pfam02494 81 V 81
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1956-2007 |
7.84e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.86 E-value: 7.84e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1956 AGNFSECSVTCGEGVEYRRVGCTRLSDSQLVTDDFCNDQ-RPSDSRPCSLPEC 2007
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1116-1171 |
1.34e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.34e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 1116 YEATPWSACSVTCALGVQTRGVSCVTRKGSGVVIDEmDCSNMTRPSESRECYLDPC 1171
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDS-ECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
757-810 |
1.35e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.35e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 757 YVATSFGDCSVSCGPGLRSRSIFCVSE-SNQVVDDSFCAGLVRQVESESCNLTPC 810
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| HYR super family |
cl47740 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2713-2786 |
9.44e-11 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
The actual alignment was detected with superfamily member pfam02494:
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 60.48 E-value: 9.44e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 2713 PVEGCPSDQNVTTDIGNATAVVYWTPPTPP--PDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVV 2786
Cdd:pfam02494 6 PTVKCPNNIVRTVELGTSTVRVFFTEPTAFdnSGQAILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFTVTV 81
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1772-1824 |
1.46e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 1.46e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1772 PGPWSECSLSCDGGVRTRDVFCMNLATRQTDREALCEGSPFYEPMEECNTEEC 1824
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1297-1347 |
5.84e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.46 E-value: 5.84e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1297 TGEWGECSVTCGVGTESRDVTCVEE--GVEVDVSTCAGLPVPPATRSCTQEDC 1347
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKggGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2303-2355 |
7.68e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.08 E-value: 7.68e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2303 ASNFSECSVSCGEGFRTRDVLCTRLETGENVSRDNCDENEILPNIEPCNEQPC 2355
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2477-2529 |
8.72e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 8.72e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 2477 TGPYSEeCSATCGEGVVYRNVTCQDLMTRAVVNDSLCSEL-RPSEIKPCRREPC 2529
Cdd:pfam19030 3 AGPWGE-CSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2658-2712 |
3.17e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.15 E-value: 3.17e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 2658 YLVTPFEECSVTCGLGEVRRDIFCVDRYTNDTVSDDQCAGDVRPIEFLPCYIDNC 2712
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1056-1112 |
4.21e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.77 E-value: 4.21e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 1056 WVSENFGDCSVTCGDGVRVRNVLCyaIAGGNFEPVVGSLCNPLLEPPSEEICDLEDC 1112
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQC--VQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
581-627 |
1.06e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 1.06e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 581 GQCSVTCGTGSETRVVNCVDSESN-IVDDSLCTD-ERPPEVIECASTPC 627
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2131-2182 |
7.72e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 51.30 E-value: 7.72e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2131 VGEYGECDVSCGSGVQTREVECTDLTTQESVAMGLCTD-PMPPSTTECNEEPC 2182
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2368-2467 |
1.58e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 52.41 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2368 FESPGFPSEYPENLQCVYDFYNINDECWRITAYYFDLQdkENDQCR-DRFFVEDvGFAGREPYIA--CGQEF-SPVLSFS 2443
Cdd:cd00041 13 ISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLE--SSPNCSyDYLEIYD-GPSTSSPLLGrfCGSTLpPPIISSG 89
|
90 100
....*....|....*....|....
gi 47551295 2444 RTIRITFFSDDKYSGRGFSAVARS 2467
Cdd:cd00041 90 NSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1595-1648 |
1.66e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 1.66e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 1595 WVPLPFGNCSEICGVGNRTRELECVNALTNELTGRDECPDEE-PPTTEPCFIEEC 1648
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKkPPETQSCNLKPC 55
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1651-1758 |
6.23e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
:
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 50.49 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1651 CDVSITAGNSQ-ITFPMSNDYYLYNDECTLTITNENGCM-MLFFTSLDIDEGlgDTCYNDYLMIFDPINVYANE--PYCG 1726
Cdd:cd00041 1 CGGTLTASTSGtISSPNYPNNYPNNLNCVWTIEAPPGYRiRLTFEDFDLESS--PNCSYDYLEIYDGPSTSSPLlgRFCG 78
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 1727 NAINTmPYKTIGNTVELTLRTEDAERFKSFEV 1758
Cdd:cd00041 79 STLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
876-922 |
2.16e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.45 E-value: 2.16e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 47551295 876 YVVGEYGQCSATCGFGIQQRSVACVDLDnDNQTVSNTQCSEAAPPSA 922
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKG-GGSIVPDSECSAQKKPPE 46
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
704-751 |
2.56e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.06 E-value: 2.56e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 704 GACSVTCGEGVQELTVFCQSLAGM-VVDDFNCASLQRPASSQICTQEIC 751
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
816-871 |
3.06e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.98 E-value: 3.06e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 816 YEVQPFPECTLPCGSQSFVRVVLCR-SSEGGVVSSTNCVGAglEAPPTTFDCNLEPC 871
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIVPDSECSAQ--KKPPETQSCNLKPC 55
|
|
| CUB super family |
cl00049 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
3598-3700 |
7.74e-05 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
The actual alignment was detected with superfamily member cd00041:
Pssm-ID: 412131 [Multi-domain] Cd Length: 113 Bit Score: 44.71 E-value: 7.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3598 CNYTIDGASmvSGNLSSPNYPNSSPSGLSCPITFIIPQGTVLNIMIVEFNL--DASCS-EYIKL----TANVAGETNFCS 3670
Cdd:cd00041 1 CGGTLTAST--SGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLesSPNCSyDYLEIydgpSTSSPLLGRFCG 78
|
90 100 110
....*....|....*....|....*....|
gi 47551295 3671 NdiTLPASATYTSDTMVsFLYVTDNDDSNT 3700
Cdd:cd00041 79 S--TLPPPIISSGNSLT-VRFRSDSSVTGR 105
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
635-688 |
1.58e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 39.36 E-value: 1.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 635 FYDNYGECSVTCDTGVQSRTAFCATSDGTSESV-EICRLLfSSVVTERTCNPVPC 688
Cdd:pfam19030 2 VAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPdSECSAQ-KKPPETQSCNLKPC 55
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ZnMc_ADAMTS_like |
cd04273 |
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) ... |
217-411 |
9.53e-72 |
|
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that combine ADAM-like metalloproteinases with thrombospondin type-1 repeats. ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteinases are inhibited by TIMPs (tissue inhibitors of metalloproteinases), and they play roles in coagulation, angiogenesis, development and progression of arthritis. They hydrolyze the von Willebrand factor precursor and various components of the extracellular matrix.
Pssm-ID: 239801 Cd Length: 207 Bit Score: 239.83 E-value: 9.53e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFD-YHGDDTEFYIFTILNQVAGLFRDKTLSADLRLLVTSITIFTAPQSNLDLTDELSHSLKNFCEWQ 295
Cdd:cd04273 1 RYVETLVVADSKMVEfHHGEDLEHYILTLMNIVASLYKDPSLGNSINIVVVRLIVLEDEESGLLISGNAQKSLKSFCRWQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 296 KDEKS---------DISILLTRRDLEIG-GNDAVTGKSkDIGGACDPSRRCIIAQDHGpSGTIFTLAHEIGHSLGIYHDD 365
Cdd:cd04273 81 KKLNPpndsdpehhDHAILLTRQDICRSnGNCDTLGLA-PVGGMCSPSRSCSINEDTG-LSSAFTIAHELGHVLGMPHDG 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 47551295 366 SESGCA---NNKNIMATDNSGGSEAFQWSLCSNKDLLQFLSTSDSVCLD 411
Cdd:cd04273 159 DGNSCGpegKDGHIMSPTLGANTGPFTWSKCSRRYLTSFLDTGDGNCLL 207
|
|
| Reprolysin |
pfam01421 |
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that ... |
217-410 |
1.44e-24 |
|
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Members of this family are also known as adamalysins. Most members of this family are snake venom endopeptidases, but there are also some mammalian proteins such as Swiss:P78325, and fertilin. Fertilin and closely related proteins appear to not have some active site residues and may not be active enzymes.
Pssm-ID: 426256 [Multi-domain] Cd Length: 200 Bit Score: 103.92 E-value: 1.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFDYHGDDTEF---YIFTILNQVAGLFRdktlSADLRLLVTSITIFTApQSNLDLTDELSHSLKNFCE 293
Cdd:pfam01421 1 KYIELFIVVDKQLFQKMGSDTTVvrqRVFQVVNLVNSIYK----ELNIRVVLVGLEIWTD-EDKIDVSGDANDTLRNFLK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 294 WQKD-----EKSDISILLTRRDLeiggNDAVTGKSKdIGGACDPSRRCIIAQDHGPSGTIF--TLAHEIGHSLGIYHDDS 366
Cdd:pfam01421 76 WRQEylkkrKPHDVAQLLSGVEF----GGTTVGAAY-VGGMCSLEYSGGVNEDHSKNLESFavTMAHELGHNLGMQHDDF 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 47551295 367 ESGC---ANNKNIMaTDNSGGSEAFQWSLCSNKDLLQFLSTSDSVCL 410
Cdd:pfam01421 151 NGGCkcpPGGGCIM-NPSAGSSFPRKFSNCSQEDFEQFLTKQKGACL 196
|
|
| Pep_M12B_propep |
pfam01562 |
Reprolysin family propeptide; This region is the propeptide for members of peptidase family ... |
56-184 |
3.34e-20 |
|
Reprolysin family propeptide; This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
Pssm-ID: 460254 Cd Length: 128 Bit Score: 88.91 E-value: 3.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 56 VKPVRL-GTRHQRSV-EERSVTSTSEYSVEGFDHVFHIQLKQTMDLFNAGLLVKRINENGQVRIEQP--ETGCYHQGHVK 131
Cdd:pfam01562 3 VIPVRLdPSRRRRSLaSESTYLDTLSYRLAAFGKKFHLHLTPNRLLLAPGFTVTYYLDGGTGVESPPvqTDHCYYQGHVE 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 132 DSEHtSSVSLSTCNGLVGMIRTPEGDFVLKPLredhivkMKSSENEVP-THIMY 184
Cdd:pfam01562 83 GHPD-SSVALSTCSGLRGFIRTENEEYLIEPL-------EKYSREEGGhPHVVY 128
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1185-1287 |
4.45e-19 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 85.16 E-value: 4.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1185 GSTTYTLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSANSL---CDEVAlPYVY 1259
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEssPNCSYDYLEIYDGPSTSSPLLgrfCGSTL-PPPI 85
|
90 100
....*....|....*....|....*...
gi 47551295 1260 ESTSPMLEVLFLTDATVNMRGFSATYQA 1287
Cdd:cd00041 86 ISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1353-1466 |
3.92e-17 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 79.76 E-value: 3.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1353 CGENILRLAPGLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTIGFLvFINGGVPCQEgDSVTIQD--TSSGEPVISLC- 1429
Cdd:cd00041 1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDF-DLESSPNCSY-DYLEIYDgpSTSSPLLGRFCg 78
|
90 100 110
....*....|....*....|....*....|....*..
gi 47551295 1430 QSTPADIISLTNEVTLTFVSDGNpaPQGTGFTLQYFS 1466
Cdd:cd00041 79 STLPPPIISSGNSLTVRFRSDSS--VTGRGFKATYSA 113
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3355-3434 |
4.08e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3355 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3433
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3434 V 3434
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3193-3272 |
4.12e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3193 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3271
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3272 V 3272
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2788-2867 |
4.24e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2788 DNEIPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 2866
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2867 V 2867
Cdd:pfam02494 81 V 81
|
|
| ADAMTS_CR_2 |
pfam17771 |
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS ... |
428-499 |
5.56e-17 |
|
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS peptidases (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) which is closely related to the ADAM family (pfam08516). Members of the ADAM-TS family have been implicated in a range of diseases. For instance, members of this family have been found to participate directly in processes in the central nervous system (CNS) such as the regulation of brain plasticity.
Pssm-ID: 465496 Cd Length: 68 Bit Score: 77.77 E-value: 5.56e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47551295 428 PGHYYDALKQCQMTFGSEATVADGYiySQDMCLELQCRVPGRSEDITNHTPALDGTKCGTGRgvMCVHGQCL 499
Cdd:pfam17771 1 PGQLYSADEQCRLIFGPGSTFCPNG--DEDVCSKLWCSNPGGSTCTTKNLPAADGTPCGNKK--WCLNGKCV 68
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1190-1285 |
8.19e-17 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 78.59 E-value: 8.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1190 TLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSANSL---CDEVALPYVYESTSP 1264
Cdd:smart00042 2 TITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLEssDNCEYDYVEIYDGPSASSPLLgrfCGSEAPPPVISSSSN 81
|
90 100
....*....|....*....|.
gi 47551295 1265 MLEVLFLTDATVNMRGFSATY 1285
Cdd:smart00042 82 SLTLTFVSDSSVQKRGFSARY 102
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3031-3110 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3031 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3109
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3110 V 3110
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3274-3353 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3274 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3352
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3353 V 3353
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2869-2948 |
1.59e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2869 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 2947
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2948 V 2948
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3112-3191 |
2.65e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 76.27 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3112 DNENPVISgCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3190
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3191 V 3191
Cdd:pfam02494 81 V 81
|
|
| Hia |
COG5295 |
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ... |
2881-3539 |
3.24e-16 |
|
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain] Cd Length: 785 Bit Score: 85.98 E-value: 3.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2881 DQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGD-DFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGC 2959
Cdd:COG5295 14 LTTVASGASTTASGSSATVTSAAQSTGSAATSSGSSSAAgGSGSTSSLTAAAATAGAGSGGTSATAASSVASGGASAATA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2960 PSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTffVVVSDNEIPVFSG 3039
Cdd:COG5295 94 ASTGTGNTAGTAATVAGAASSGSATNAGASAGASAAAAAGSTAAAGGAAASTGGSSAAGGSNTAT--ATGSSTANAATAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3040 CPSDQNVTTDI----GNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNEN 3115
Cdd:COG5295 172 AGATSTSASGSssgaSGAAAASAATGASAGGTASAAASASSSATGTSASVGVNAGAATGSAASAGGSASAGAASGNATTA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3116 PVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNE 3195
Cdd:COG5295 252 SASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGGGAAALGSAGGSSG 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3196 NPVISGcpSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFfVVVSDN 3275
Cdd:COG5295 332 VGTASG--ASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGSGGSS-TGASAG 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3276 EIPVFSGCPSDQNVTTDIGNATAVVIWTpptATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSD 3355
Cdd:COG5295 409 GGASAAGGAAAGSAAAGTSSNTSAVGAS---NGASGTSSSASSAGAAGGGTAGAGGAANVGAATTAASAAATAAAATSSA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3356 NENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3435
Cdd:COG5295 486 AIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGSTTAATGTNSVAVGNNTATG 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATD--NSVNQTLTSTNNPGddfpIGNNTVTYSASDDA-GNTETCTff 3512
Cdd:COG5295 566 ANSVALGAGSVASGANSVSVGAAGAENVAAGATDTDavNGGGAVATGDNSVA----VGNNAQASGANSVAlGAGATAT-- 639
|
650 660
....*....|....*....|....*....
gi 47551295 3513 vvvsdNENPVISGCPSDQNVA--ISIGNA 3539
Cdd:COG5295 640 -----ANNSVALGAGSVADRAntVSVGSA 663
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2950-3029 |
1.36e-15 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 74.35 E-value: 1.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2950 DNEIPVISgCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 3028
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3029 V 3029
Cdd:pfam02494 81 V 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2542-2647 |
6.09e-15 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 73.19 E-value: 6.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2542 YISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDLILAEDPyfaLDQAYCGNQENFL 2621
Cdd:smart00042 2 TITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSD---NC-EYDYVEIYDGPSASSP---LLGRFCGSEAPPP 74
|
90 100
....*....|....*....|....*..
gi 47551295 2622 WFSTQ-NLAVLSFLSNDEGVYPGYQIY 2647
Cdd:smart00042 75 VISSSsNSLTLTFVSDSSVQKRGFSAR 101
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2014-2118 |
6.43e-15 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 73.60 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2014 LTEEGIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLgRFELgLTNGDCEAgDYIELTDENWEY--LDATYCGGSLPP 2091
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFE-DFDL-ESSPNCSY-DYLEIYDGPSTSspLLGRFCGSTLPP 83
|
90 100
....*....|....*....|....*..
gi 47551295 2092 VWRSRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:cd00041 84 PIISSGNSLTVRFRSDSSVTGRGFKAT 110
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3436-3515 |
1.07e-14 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 71.65 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISgCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3514
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3515 V 3515
Cdd:pfam02494 81 V 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2018-2118 |
2.18e-14 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 71.65 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2018 GIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLgRFELgLTNGDCEAgDYIELTDENWEY--LDATYCGGSLPPVW-R 2094
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFT-DFDL-ESSDNCEY-DYVEIYDGPSASspLLGRFCGSEAPPPViS 77
|
90 100
....*....|....*....|....
gi 47551295 2095 SRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:smart00042 78 SSSNSLTLTFVSDSSVQKRGFSAR 101
|
|
| CUB |
pfam00431 |
CUB domain; |
1190-1285 |
2.65e-14 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 71.56 E-value: 2.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1190 TLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSAN---SLCDEVaLPYVYESTSP 1264
Cdd:pfam00431 11 SISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEdhDECGYDYVEIRDGPSASSPllgRFCGSG-IPEDIVSSSN 89
|
90 100
....*....|....*....|.
gi 47551295 1265 MLEVLFLTDATVNMRGFSATY 1285
Cdd:pfam00431 90 QMTIKFVSDASVQKRGFKATY 110
|
|
| CUB |
pfam00431 |
CUB domain; |
2010-2118 |
4.06e-14 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 71.17 E-value: 4.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2010 CDMVLTEE-GIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLGrFELGlTNGDCeAGDYIELTDENWEY--LDATYCG 2086
Cdd:pfam00431 1 CGGVLTDSsGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQD-FELE-DHDEC-GYDYVEIRDGPSASspLLGRFCG 77
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 2087 GSLPPVWRSRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:pfam00431 78 SGIPEDIVSSSNQMTIKFVSDASVQKRGFKAT 109
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2534-2650 |
2.10e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 68.98 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2534 TFIVQDAQYISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDLILAEDPyfaLDQAY 2613
Cdd:cd00041 4 TLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSP---NC-SYDYLEIYDGPSTSSP---LLGRF 76
|
90 100 110
....*....|....*....|....*....|....*..
gi 47551295 2614 CGNQENFLWFSTQNLAVLSFLSNDEGVYPGYQIYSTF 2650
Cdd:cd00041 77 CGSTLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1474-1583 |
3.04e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 68.59 E-value: 3.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1474 CGGNITTSGQ-PIYSPNYPANYDDNVTCVTDITNDEGC-ISIEFLMMDIDNgdyvNDTCMEDSLTITD---YNNPSLSRT 1548
Cdd:cd00041 1 CGGTLTASTSgTISSPNYPNNYPNNLNCVWTIEAPPGYrIRLTFEDFDLES----SPNCSYDYLEIYDgpsTSSPLLGRF 76
|
90 100 110
....*....|....*....|....*....|....*
gi 47551295 1549 nCGDSTPEsPWLSASGNVKVSFTSNGANSSQGYIA 1583
Cdd:cd00041 77 -CGSTLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1363-1464 |
4.54e-13 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 67.80 E-value: 4.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1363 GLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTigFLVF-INGGVPCqEGDSVTIQD--TSSGEPVISLC--QSTPADII 1437
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQ--FTDFdLESSDNC-EYDYVEIYDgpSASSPLLGRFCgsEAPPPVIS 77
|
90 100
....*....|....*....|....*..
gi 47551295 1438 SLTNEVTLTFVSDGNpaPQGTGFTLQY 1464
Cdd:smart00042 78 SSSNSLTLTFVSDSS--VQKRGFSARY 102
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1827-1941 |
8.28e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 67.44 E-value: 8.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1827 CSEDVT--RPGVIVSPGFgtedhygnYDGYDNNLNCIYNITNPNSTEcITVSFISFDLgQPSENCS-DYVQITDTEGGVD 1903
Cdd:cd00041 1 CGGTLTasTSGTISSPNY--------PNNYPNNLNCVWTIEAPPGYR-IRLTFEDFDL-ESSPNCSyDYLEIYDGPSTSS 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 47551295 1904 FL---YCGlpeNTTAPVFYSRSANVEVVFRTGEDERNDGFE 1941
Cdd:cd00041 71 PLlgrFCG---STLPPPIISSGNSLTVRFRSDSSVTGRGFK 108
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
996-1051 |
1.53e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.78 E-value: 1.53e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 996 WRIGAWSPCSVSCGNGVETRVVYCVEsEDSNVIIPSTSCDPAAEPASVQICNPGDC 1051
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQ-KGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3517-3595 |
1.66e-12 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 65.49 E-value: 1.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3517 DNENPVISgCPSDQNVAISIGNA-AVVTWTPPTATDNSGNQTLTSTNN-PGDDFTIGNNTVTYSASDDAGNTEYCTFFVV 3594
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTStVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3595 V 3595
Cdd:pfam02494 81 V 81
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1956-2007 |
7.84e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.86 E-value: 7.84e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1956 AGNFSECSVTCGEGVEYRRVGCTRLSDSQLVTDDFCNDQ-RPSDSRPCSLPEC 2007
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1116-1171 |
1.34e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.34e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 1116 YEATPWSACSVTCALGVQTRGVSCVTRKGSGVVIDEmDCSNMTRPSESRECYLDPC 1171
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDS-ECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
757-810 |
1.35e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.35e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 757 YVATSFGDCSVSCGPGLRSRSIFCVSE-SNQVVDDSFCAGLVRQVESESCNLTPC 810
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1485-1583 |
1.45e-11 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 63.56 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1485 IYSPNYPANYDDNVTCVTDITNDEGC-ISIEFLMMDIDNgdyvNDTCMEDSLTITD---YNNPSLSRTnCGDSTPESPWL 1560
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGYrIELQFTDFDLES----SDNCEYDYVEIYDgpsASSPLLGRF-CGSEAPPPVIS 77
|
90 100
....*....|....*....|...
gi 47551295 1561 SASGNVKVSFTSNGANSSQGYIA 1583
Cdd:smart00042 78 SSSNSLTLTFVSDSSVQKRGFSA 100
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2713-2786 |
9.44e-11 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 60.48 E-value: 9.44e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 2713 PVEGCPSDQNVTTDIGNATAVVYWTPPTPP--PDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVV 2786
Cdd:pfam02494 6 PTVKCPNNIVRTVELGTSTVRVFFTEPTAFdnSGQAILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFTVTV 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1835-1941 |
1.12e-10 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 60.87 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1835 GVIVSPGFGtedhygnyDGYDNNLNCIYNITNPNSTEcITVSFISFDLgQPSENCS-DYVQITDTEGGVDFL---YCGlp 1910
Cdd:smart00042 1 GTITSPNYP--------QSYPNNLDCVWTIRAPPGYR-IELQFTDFDL-ESSDNCEyDYVEIYDGPSASSPLlgrFCG-- 68
|
90 100 110
....*....|....*....|....*....|.
gi 47551295 1911 ENTTAPVFYSRSANVEVVFRTGEDERNDGFE 1941
Cdd:smart00042 69 SEAPPPVISSSSNSLTLTFVSDSSVQKRGFS 99
|
|
| CUB |
pfam00431 |
CUB domain; |
1353-1464 |
1.35e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 61.16 E-value: 1.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1353 CGENILRlAPGLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTigFLVF-INGGVPCQeGDSVTIQDTSSGEPVI--SLC 1429
Cdd:pfam00431 1 CGGVLTD-SSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLT--FQDFeLEDHDECG-YDYVEIRDGPSASSPLlgRFC 76
|
90 100 110
....*....|....*....|....*....|....*.
gi 47551295 1430 QST-PADIISLTNEVTLTFVSDGNpaPQGTGFTLQY 1464
Cdd:pfam00431 77 GSGiPEDIVSSSNQMTIKFVSDAS--VQKRGFKATY 110
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1772-1824 |
1.46e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 1.46e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1772 PGPWSECSLSCDGGVRTRDVFCMNLATRQTDREALCEGSPFYEPMEECNTEEC 1824
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| CUB |
pfam00431 |
CUB domain; |
1474-1581 |
4.04e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 59.62 E-value: 4.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1474 CGGNITTSGQPIYSPNYPANYDDNVTCVTDITNDEG-CISIEFLMMDIdngdYVNDTCMEDSLTITD---YNNPSLSRTn 1549
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGfRVKLTFQDFEL----EDHDECGYDYVEIRDgpsASSPLLGRF- 75
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 1550 CGDSTPEsPWLSASGNVKVSFTSNGANSSQGY 1581
Cdd:pfam00431 76 CGSGIPE-DIVSSSNQMTIKFVSDASVQKRGF 106
|
|
| CUB |
pfam00431 |
CUB domain; |
2532-2647 |
4.16e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 59.62 E-value: 4.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2532 CDTFIVQDAQYISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDlilAEDPYFALDQ 2611
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHD---EC-GYDYVEIRD---GPSASSPLLG 73
|
90 100 110
....*....|....*....|....*....|....*...
gi 47551295 2612 AYCGNQ--ENFlwFSTQNLAVLSFLSNDEGVYPGYQIY 2647
Cdd:pfam00431 74 RFCGSGipEDI--VSSSNQMTIKFVSDASVQKRGFKAT 109
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1297-1347 |
5.84e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.46 E-value: 5.84e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1297 TGEWGECSVTCGVGTESRDVTCVEE--GVEVDVSTCAGLPVPPATRSCTQEDC 1347
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKggGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2303-2355 |
7.68e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.08 E-value: 7.68e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2303 ASNFSECSVSCGEGFRTRDVLCTRLETGENVSRDNCDENEILPNIEPCNEQPC 2355
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2477-2529 |
8.72e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 8.72e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 2477 TGPYSEeCSATCGEGVVYRNVTCQDLMTRAVVNDSLCSEL-RPSEIKPCRREPC 2529
Cdd:pfam19030 3 AGPWGE-CSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2658-2712 |
3.17e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.15 E-value: 3.17e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 2658 YLVTPFEECSVTCGLGEVRRDIFCVDRYTNDTVSDDQCAGDVRPIEFLPCYIDNC 2712
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1056-1112 |
4.21e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.77 E-value: 4.21e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 1056 WVSENFGDCSVTCGDGVRVRNVLCyaIAGGNFEPVVGSLCNPLLEPPSEEICDLEDC 1112
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQC--VQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
581-627 |
1.06e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 1.06e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 581 GQCSVTCGTGSETRVVNCVDSESN-IVDDSLCTD-ERPPEVIECASTPC 627
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2131-2182 |
7.72e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 51.30 E-value: 7.72e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2131 VGEYGECDVSCGSGVQTREVECTDLTTQESVAMGLCTD-PMPPSTTECNEEPC 2182
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2368-2467 |
1.58e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 52.41 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2368 FESPGFPSEYPENLQCVYDFYNINDECWRITAYYFDLQdkENDQCR-DRFFVEDvGFAGREPYIA--CGQEF-SPVLSFS 2443
Cdd:cd00041 13 ISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLE--SSPNCSyDYLEIYD-GPSTSSPLLGrfCGSTLpPPIISSG 89
|
90 100
....*....|....*....|....
gi 47551295 2444 RTIRITFFSDDKYSGRGFSAVARS 2467
Cdd:cd00041 90 NSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1595-1648 |
1.66e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 1.66e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 1595 WVPLPFGNCSEICGVGNRTRELECVNALTNELTGRDECPDEE-PPTTEPCFIEEC 1648
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKkPPETQSCNLKPC 55
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2368-2463 |
4.40e-07 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 50.85 E-value: 4.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2368 FESPGFPSEYPENLQCVYDFYNINDEcwRITAY--YFDLQDkeNDQCR-DRFFVEDVGFAGREPY-IACGQEFSPVL--S 2441
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGY--RIELQftDFDLES--SDNCEyDYVEIYDGPSASSPLLgRFCGSEAPPPVisS 78
|
90 100
....*....|....*....|..
gi 47551295 2442 FSRTIRITFFSDDKYSGRGFSA 2463
Cdd:smart00042 79 SSNSLTLTFVSDSSVQKRGFSA 100
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1651-1758 |
6.23e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 50.49 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1651 CDVSITAGNSQ-ITFPMSNDYYLYNDECTLTITNENGCM-MLFFTSLDIDEGlgDTCYNDYLMIFDPINVYANE--PYCG 1726
Cdd:cd00041 1 CGGTLTASTSGtISSPNYPNNYPNNLNCVWTIEAPPGYRiRLTFEDFDLESS--PNCSYDYLEIYDGPSTSSPLlgRFCG 78
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 1727 NAINTmPYKTIGNTVELTLRTEDAERFKSFEV 1758
Cdd:cd00041 79 STLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
876-922 |
2.16e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.45 E-value: 2.16e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 47551295 876 YVVGEYGQCSATCGFGIQQRSVACVDLDnDNQTVSNTQCSEAAPPSA 922
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKG-GGSIVPDSECSAQKKPPE 46
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
704-751 |
2.56e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.06 E-value: 2.56e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 704 GACSVTCGEGVQELTVFCQSLAGM-VVDDFNCASLQRPASSQICTQEIC 751
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1297-1348 |
3.06e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 46.81 E-value: 3.06e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 1297 TGEWGECSVTCGVGTESRDVTCVEEGVEVDVSTCAGLpvPPATRSCTQEDCP 1348
Cdd:smart00209 4 WSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGE--DVETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1119-1172 |
5.84e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 46.04 E-value: 5.84e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 1119 TPWSACSVTCALGVQTRGVSCVTRKGSGvviDEMDCSnmTRPSESRECYLDPCP 1172
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQN---GGGPCT--GEDVETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
995-1051 |
2.13e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 44.50 E-value: 2.13e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 995 VWRIGAWSPCSVSCGNGVETRVVYCVeseDSNVIIPSTSCDPAAEpaSVQICNPGDC 1051
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCC---SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
816-871 |
3.06e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.98 E-value: 3.06e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 816 YEVQPFPECTLPCGSQSFVRVVLCR-SSEGGVVSSTNCVGAglEAPPTTFDCNLEPC 871
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIVPDSECSAQ--KKPPETQSCNLKPC 55
|
|
| CUB |
pfam00431 |
CUB domain; |
1827-1940 |
3.93e-05 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 45.36 E-value: 3.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1827 CSEDVTRP-GVIVSPGFGtedhygnyDGYDNNLNCIYNI-TNPNSTecITVSFISFDLGQPSENCSDYVQITDTEGGVDF 1904
Cdd:pfam00431 1 CGGVLTDSsGSISSPNYP--------NPYPPNKDCVWLIrAPPGFR--VKLTFQDFELEDHDECGYDYVEIRDGPSASSP 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 47551295 1905 L---YCG--LPenttaPVFYSRSANVEVVFRTGEDERNDGF 1940
Cdd:pfam00431 71 LlgrFCGsgIP-----EDIVSSSNQMTIKFVSDASVQKRGF 106
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1662-1758 |
5.77e-05 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 44.69 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1662 ITFPMSNDYYLYNDECTLTITNENGCM-MLFFTSLDIDEGlgDTCYNDYLMIFDPINVYANE--PYCGNAINTMPYKTIG 1738
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGYRiELQFTDFDLESS--DNCEYDYVEIYDGPSASSPLlgRFCGSEAPPPVISSSS 80
|
90 100
....*....|....*....|
gi 47551295 1739 NTVELTLRTEDAERFKSFEV 1758
Cdd:smart00042 81 NSLTLTFVSDSSVQKRGFSA 100
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
760-810 |
5.99e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.96 E-value: 5.99e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 760 TSFGDCSVSCGPGLRSRSIFCVSESNQvVDDSFCAGLvrQVESESCNLTPC 810
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPCTGE--DVETRACNEQPC 52
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
3598-3700 |
7.74e-05 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 44.71 E-value: 7.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3598 CNYTIDGASmvSGNLSSPNYPNSSPSGLSCPITFIIPQGTVLNIMIVEFNL--DASCS-EYIKL----TANVAGETNFCS 3670
Cdd:cd00041 1 CGGTLTAST--SGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLesSPNCSyDYLEIydgpSTSSPLLGRFCG 78
|
90 100 110
....*....|....*....|....*....|
gi 47551295 3671 NdiTLPASATYTSDTMVsFLYVTDNDDSNT 3700
Cdd:cd00041 79 S--TLPPPIISSGNSLT-VRFRSDSSVTGR 105
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1773-1825 |
8.53e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.57 E-value: 8.53e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1773 GPWSECSLSCDGGVRTRDVFCMNlaTRQTDREALCEGSPFyEpMEECNTEECP 1825
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGEDV-E-TRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1957-2008 |
1.24e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.19 E-value: 1.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 1957 GNFSECSVTCGEGVEYRRVGCTrlSDSQLVTDDFCNDQRPsDSRPCSLPECP 2008
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCC--SPPPQNGGGPCTGEDV-ETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2132-2182 |
1.35e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.19 E-value: 1.35e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 2132 GEYGECDVSCGSGVQTREVECTDltTQESVAMGLCTDPmPPSTTECNEEPC 2182
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGE-DVETRACNEQPC 52
|
|
| PRK12688 |
PRK12688 |
flagellin; Reviewed |
2794-3242 |
3.27e-04 |
|
flagellin; Reviewed
Pssm-ID: 171664 [Multi-domain] Cd Length: 751 Bit Score: 46.80 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2794 ISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPI-GNNTVTYSASDDAGNTETCTFFVVVSDNEI 2872
Cdd:PRK12688 102 VVGYSTKSNVSTTISGATADDLRGTTSYASATASSNVLYDGAAGGATAAtGATTLGGTAGSLAGTGATAGDGTTALTGTI 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2873 PVFSGCPSdqNVTTDIGNAtavviwtPPTATD----NSGNQTLTSTNNPGDD-FPIGNNTVTYSANDDAGNTETCTFFVV 2947
Cdd:PRK12688 182 TLIATNGT--TATGLLGNA-------QPADGDtltvNGKTITFRSGAAPASTaVPSGSGVSGNLVTDGNGNSTVYLGSAT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2948 VSD--NEIPVISGCPSdqnvATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPI------------------GNN 3007
Cdd:PRK12688 253 VNDllSAIDLASGVQT----VTISSGAATIAVSASGGAVSAAAAGAVTLKSSTGADLSVtgkadllkalglttatgaGNA 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3008 TVTYSANDDAG--------------NTETCTFfvvvSDNEIP----VFSGCPSDQNVTTDiGNATAVVIWTPPTATD--- 3066
Cdd:PRK12688 329 TVNANRTTSAGslgaliqdgstlnvDGKTITF----KNAPIPgaasVPSGYGASGNVLTD-GNGNSTVYLQGGTINDvlk 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3067 ----NSGSQTLTSTNnpgddfpiGNNTVTYSASDDAGNtetctffvIVSDNENPVISGCPSDQNVaTDIGNATAVVIWTP 3142
Cdd:PRK12688 404 aidlATGVQTATIAN--------GTATLATAAGQTASS--------VNASGQLKLSTGLNADLSI-TGTGNALSALGLAG 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3143 PTATDNSGNQTLTSTNNpgddfPIGNNTVTYSASDDaGNTETCTFfvvvSDNENPVISGCpSDQNVTTDIGNATAVVIWT 3222
Cdd:PRK12688 467 NTGTATAFTAARTAGAG-----GISGKTLTFTSFNG-GTAVNVTF----GDGTNGTVKTL-AQLNTALQANNLTATIDAT 535
|
490 500
....*....|....*....|...
gi 47551295 3223 PP---TATDNSGSQTLTSTNNPG 3242
Cdd:PRK12688 536 GKltiSASNDYASSTLGSTLAGG 558
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2304-2355 |
3.45e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 3.45e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 2304 SNFSECSVSCGEGFRTRDVLCTRleTGENVSRDNCDENEilPNIEPCNEQPC 2355
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGED--VETRACNEQPC 52
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
3610-3700 |
7.54e-04 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 41.61 E-value: 7.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3610 GNLSSPNYPNSSPSGLSCPITFIIPQGTVLNIMIVEFNLDASCS---EYIKLT--ANVAGET--NFCSNdiTLPASATYT 3682
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDNceyDYVEIYdgPSASSPLlgRFCGS--EAPPPVISS 78
|
90
....*....|....*...
gi 47551295 3683 SDTMVSFLYVTDNDDSNT 3700
Cdd:smart00042 79 SSNSLTLTFVSDSSVQKR 96
|
|
| CUB |
pfam00431 |
CUB domain; |
2361-2463 |
8.78e-04 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 41.51 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2361 FFGDSALFESPGFPSEYPENLQCVydfynindecWRITAYY----------FDLQDkeNDQCRDRFFVEDVGFAGREPYI 2430
Cdd:pfam00431 5 LTDSSGSISSPNYPNPYPPNKDCV----------WLIRAPPgfrvkltfqdFELED--HDECGYDYVEIRDGPSASSPLL 72
|
90 100 110
....*....|....*....|....*....|....*.
gi 47551295 2431 A--CGQEFS-PVLSFSRTIRITFFSDDKYSGRGFSA 2463
Cdd:pfam00431 73 GrfCGSGIPeDIVSSSNQMTIKFVSDASVQKRGFKA 108
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
635-688 |
1.58e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 39.36 E-value: 1.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 635 FYDNYGECSVTCDTGVQSRTAFCATSDGTSESV-EICRLLfSSVVTERTCNPVPC 688
Cdd:pfam19030 2 VAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPdSECSAQ-KKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1599-1649 |
1.85e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 39.11 E-value: 1.85e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 1599 PFGNCSEICGVGNRTRELECVNAltNELTGRDECPdEEPPTTEPCFIEECP 1649
Cdd:smart00209 6 EWSPCSVTCGGGVQTRTRSCCSP--PPQNGGGPCT-GEDVETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2478-2530 |
2.92e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 38.34 E-value: 2.92e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 2478 GPYSE--ECSATCGEGVVYRNVTCQDlmTRAVVNDSLCSELRPsEIKPCRREPCP 2530
Cdd:smart00209 2 SEWSEwsPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGEDV-ETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
581-628 |
4.77e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 37.95 E-value: 4.77e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 47551295 581 GQCSVTCGTGSETRVVNCVDSESNiVDDSLCTDERpPEVIECASTPCP 628
Cdd:smart00209 8 SPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPCTGED-VETRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1062-1112 |
9.24e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 36.80 E-value: 9.24e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 1062 GDCSVTCGDGVRVRNVLCYAIAGgnfePVVGSLCNPllEPPSEEICDLEDC 1112
Cdd:smart00209 8 SPCSVTCGGGVQTRTRSCCSPPP----QNGGGPCTG--EDVETRACNEQPC 52
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ZnMc_ADAMTS_like |
cd04273 |
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) ... |
217-411 |
9.53e-72 |
|
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that combine ADAM-like metalloproteinases with thrombospondin type-1 repeats. ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteinases are inhibited by TIMPs (tissue inhibitors of metalloproteinases), and they play roles in coagulation, angiogenesis, development and progression of arthritis. They hydrolyze the von Willebrand factor precursor and various components of the extracellular matrix.
Pssm-ID: 239801 Cd Length: 207 Bit Score: 239.83 E-value: 9.53e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFD-YHGDDTEFYIFTILNQVAGLFRDKTLSADLRLLVTSITIFTAPQSNLDLTDELSHSLKNFCEWQ 295
Cdd:cd04273 1 RYVETLVVADSKMVEfHHGEDLEHYILTLMNIVASLYKDPSLGNSINIVVVRLIVLEDEESGLLISGNAQKSLKSFCRWQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 296 KDEKS---------DISILLTRRDLEIG-GNDAVTGKSkDIGGACDPSRRCIIAQDHGpSGTIFTLAHEIGHSLGIYHDD 365
Cdd:cd04273 81 KKLNPpndsdpehhDHAILLTRQDICRSnGNCDTLGLA-PVGGMCSPSRSCSINEDTG-LSSAFTIAHELGHVLGMPHDG 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 47551295 366 SESGCA---NNKNIMATDNSGGSEAFQWSLCSNKDLLQFLSTSDSVCLD 411
Cdd:cd04273 159 DGNSCGpegKDGHIMSPTLGANTGPFTWSKCSRRYLTSFLDTGDGNCLL 207
|
|
| ZnMc_adamalysin_II_like |
cd04269 |
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom ... |
217-410 |
2.00e-30 |
|
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
Pssm-ID: 239797 [Multi-domain] Cd Length: 194 Bit Score: 120.80 E-value: 2.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFDYHGDD---TEFYIFTILNQVAGLFRdktlSADLRLLVTSITIFTapQSNL-DLTDELSHSLKNFC 292
Cdd:cd04269 1 KYVELVVVVDNSLYKKYGSNlskVRQRVIEIVNIVDSIYR----PLNIRVVLVGLEIWT--DKDKiSVSGDAGETLNRFL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 293 EWQKDE-----KSDISILLTRRDLEigGNDAvtGKSKdIGGACDPSRRCIIAQDHGPSGTIF--TLAHEIGHSLGIYHDD 365
Cdd:cd04269 75 DWKRSNllprkPHDNAQLLTGRDFD--GNTV--GLAY-VGGMCSPKYSGGVVQDHSRNLLLFavTMAHELGHNLGMEHDD 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 47551295 366 SESGCANNKNIMATDNSGGSEAFqwSLCSNKDLLQFLSTSDSVCL 410
Cdd:cd04269 150 GGCTCGRSTCIMAPSPSSLTDAF--SNCSYEDYQKFLSRGGGQCL 192
|
|
| Reprolysin |
pfam01421 |
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that ... |
217-410 |
1.44e-24 |
|
Reprolysin (M12B) family zinc metalloprotease; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Members of this family are also known as adamalysins. Most members of this family are snake venom endopeptidases, but there are also some mammalian proteins such as Swiss:P78325, and fertilin. Fertilin and closely related proteins appear to not have some active site residues and may not be active enzymes.
Pssm-ID: 426256 [Multi-domain] Cd Length: 200 Bit Score: 103.92 E-value: 1.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFDYHGDDTEF---YIFTILNQVAGLFRdktlSADLRLLVTSITIFTApQSNLDLTDELSHSLKNFCE 293
Cdd:pfam01421 1 KYIELFIVVDKQLFQKMGSDTTVvrqRVFQVVNLVNSIYK----ELNIRVVLVGLEIWTD-EDKIDVSGDANDTLRNFLK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 294 WQKD-----EKSDISILLTRRDLeiggNDAVTGKSKdIGGACDPSRRCIIAQDHGPSGTIF--TLAHEIGHSLGIYHDDS 366
Cdd:pfam01421 76 WRQEylkkrKPHDVAQLLSGVEF----GGTTVGAAY-VGGMCSLEYSGGVNEDHSKNLESFavTMAHELGHNLGMQHDDF 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 47551295 367 ESGC---ANNKNIMaTDNSGGSEAFQWSLCSNKDLLQFLSTSDSVCL 410
Cdd:pfam01421 151 NGGCkcpPGGGCIM-NPSAGSSFPRKFSNCSQEDFEQFLTKQKGACL 196
|
|
| ZnMc_ADAM_like |
cd04267 |
Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ... |
217-403 |
4.77e-22 |
|
Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ADAM family of metalloproteases contains proteolytic domains from snake venoms, proteases from the mammalian reproductive tract, and the tumor necrosis factor alpha convertase, TACE. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions.
Pssm-ID: 239795 Cd Length: 192 Bit Score: 96.72 E-value: 4.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 217 KYIETSVVADSKMFDY---HGDDTEFYIFTILNQVAGLFRDKTLSADLRLLVTSITIFTAPQSNLDLTDELSHSLKNFCE 293
Cdd:cd04267 1 REIELVVVADHRMVSYfnsDENILQAYITELINIANSIYRSTNLRLGIRISLEGLQILKGEQFAPPIDSDASNTLNSFSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 294 WQKDE--KSDISILLTRRDLeigGNDAVTGKSKdIGGACDPSRRCIIAQDHGPSG-TIFTLAHEIGHSLGIYHDDS---- 366
Cdd:cd04267 81 WRAEGpiRHDNAVLLTAQDF---IEGDILGLAY-VGSMCNPYSSVGVVEDTGFTLlTALTMAHELGHNLGAEHDGGdela 156
|
170 180 190
....*....|....*....|....*....|....*...
gi 47551295 367 ESGCANNKNIMA-TDNSGGSeaFQWSLCSNKDLLQFLS 403
Cdd:cd04267 157 FECDGGGNYIMApVDSGLNS--YRFSQCSIGSIREFLD 192
|
|
| Pep_M12B_propep |
pfam01562 |
Reprolysin family propeptide; This region is the propeptide for members of peptidase family ... |
56-184 |
3.34e-20 |
|
Reprolysin family propeptide; This region is the propeptide for members of peptidase family M12B. The propeptide contains a sequence motif similar to the "cysteine switch" of the matrixins. This motif is found at the C terminus of the alignment but is not well aligned.
Pssm-ID: 460254 Cd Length: 128 Bit Score: 88.91 E-value: 3.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 56 VKPVRL-GTRHQRSV-EERSVTSTSEYSVEGFDHVFHIQLKQTMDLFNAGLLVKRINENGQVRIEQP--ETGCYHQGHVK 131
Cdd:pfam01562 3 VIPVRLdPSRRRRSLaSESTYLDTLSYRLAAFGKKFHLHLTPNRLLLAPGFTVTYYLDGGTGVESPPvqTDHCYYQGHVE 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 132 DSEHtSSVSLSTCNGLVGMIRTPEGDFVLKPLredhivkMKSSENEVP-THIMY 184
Cdd:pfam01562 83 GHPD-SSVALSTCSGLRGFIRTENEEYLIEPL-------EKYSREEGGhPHVVY 128
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1185-1287 |
4.45e-19 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 85.16 E-value: 4.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1185 GSTTYTLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSANSL---CDEVAlPYVY 1259
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLEssPNCSYDYLEIYDGPSTSSPLLgrfCGSTL-PPPI 85
|
90 100
....*....|....*....|....*...
gi 47551295 1260 ESTSPMLEVLFLTDATVNMRGFSATYQA 1287
Cdd:cd00041 86 ISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1353-1466 |
3.92e-17 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 79.76 E-value: 3.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1353 CGENILRLAPGLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTIGFLvFINGGVPCQEgDSVTIQD--TSSGEPVISLC- 1429
Cdd:cd00041 1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDF-DLESSPNCSY-DYLEIYDgpSTSSPLLGRFCg 78
|
90 100 110
....*....|....*....|....*....|....*..
gi 47551295 1430 QSTPADIISLTNEVTLTFVSDGNpaPQGTGFTLQYFS 1466
Cdd:cd00041 79 STLPPPIISSGNSLTVRFRSDSS--VTGRGFKATYSA 113
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3355-3434 |
4.08e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3355 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3433
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3434 V 3434
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3193-3272 |
4.12e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3193 DNENPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3271
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3272 V 3272
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2788-2867 |
4.24e-17 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 78.58 E-value: 4.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2788 DNEIPVISgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 2866
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2867 V 2867
Cdd:pfam02494 81 V 81
|
|
| ADAMTS_CR_2 |
pfam17771 |
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS ... |
428-499 |
5.56e-17 |
|
ADAMTS cysteine-rich domain 2; This cysteine rich domain is found in a variety of ADAMTS peptidases (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) which is closely related to the ADAM family (pfam08516). Members of the ADAM-TS family have been implicated in a range of diseases. For instance, members of this family have been found to participate directly in processes in the central nervous system (CNS) such as the regulation of brain plasticity.
Pssm-ID: 465496 Cd Length: 68 Bit Score: 77.77 E-value: 5.56e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47551295 428 PGHYYDALKQCQMTFGSEATVADGYiySQDMCLELQCRVPGRSEDITNHTPALDGTKCGTGRgvMCVHGQCL 499
Cdd:pfam17771 1 PGQLYSADEQCRLIFGPGSTFCPNG--DEDVCSKLWCSNPGGSTCTTKNLPAADGTPCGNKK--WCLNGKCV 68
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1190-1285 |
8.19e-17 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 78.59 E-value: 8.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1190 TLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSANSL---CDEVALPYVYESTSP 1264
Cdd:smart00042 2 TITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLEssDNCEYDYVEIYDGPSASSPLLgrfCGSEAPPPVISSSSN 81
|
90 100
....*....|....*....|.
gi 47551295 1265 MLEVLFLTDATVNMRGFSATY 1285
Cdd:smart00042 82 SLTLTFVSDSSVQKRGFSARY 102
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3031-3110 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3031 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3109
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3110 V 3110
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3274-3353 |
1.25e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3274 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVI 3352
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3353 V 3353
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2869-2948 |
1.59e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 77.04 E-value: 1.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2869 DNEIPVFSgCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 2947
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 2948 V 2948
Cdd:pfam02494 81 V 81
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3112-3191 |
2.65e-16 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 76.27 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3112 DNENPVISgCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3190
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3191 V 3191
Cdd:pfam02494 81 V 81
|
|
| Hia |
COG5295 |
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ... |
2881-3539 |
3.24e-16 |
|
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain] Cd Length: 785 Bit Score: 85.98 E-value: 3.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2881 DQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGD-DFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGC 2959
Cdd:COG5295 14 LTTVASGASTTASGSSATVTSAAQSTGSAATSSGSSSAAgGSGSTSSLTAAAATAGAGSGGTSATAASSVASGGASAATA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2960 PSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTffVVVSDNEIPVFSG 3039
Cdd:COG5295 94 ASTGTGNTAGTAATVAGAASSGSATNAGASAGASAAAAAGSTAAAGGAAASTGGSSAAGGSNTAT--ATGSSTANAATAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3040 CPSDQNVTTDI----GNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNEN 3115
Cdd:COG5295 172 AGATSTSASGSssgaSGAAAASAATGASAGGTASAAASASSSATGTSASVGVNAGAATGSAASAGGSASAGAASGNATTA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3116 PVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNE 3195
Cdd:COG5295 252 SASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGGGAAALGSAGGSSG 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3196 NPVISGcpSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFfVVVSDN 3275
Cdd:COG5295 332 VGTASG--ASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGSGGSS-TGASAG 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3276 EIPVFSGCPSDQNVTTDIGNATAVVIWTpptATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSD 3355
Cdd:COG5295 409 GGASAAGGAAAGSAAAGTSSNTSAVGAS---NGASGTSSSASSAGAAGGGTAGAGGAANVGAATTAASAAATAAAATSSA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3356 NENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3435
Cdd:COG5295 486 AIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGSTTAATGTNSVAVGNNTATG 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATD--NSVNQTLTSTNNPGddfpIGNNTVTYSASDDA-GNTETCTff 3512
Cdd:COG5295 566 ANSVALGAGSVASGANSVSVGAAGAENVAAGATDTDavNGGGAVATGDNSVA----VGNNAQASGANSVAlGAGATAT-- 639
|
650 660
....*....|....*....|....*....
gi 47551295 3513 vvvsdNENPVISGCPSDQNVA--ISIGNA 3539
Cdd:COG5295 640 -----ANNSVALGAGSVADRAntVSVGSA 663
|
|
| Hia |
COG5295 |
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ... |
2962-3585 |
1.01e-15 |
|
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain] Cd Length: 785 Bit Score: 84.44 E-value: 1.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2962 DQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGD-DFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGC 3040
Cdd:COG5295 14 LTTVASGASTTASGSSATVTSAAQSTGSAATSSGSSSAAgGSGSTSSLTAAAATAGAGSGGTSATAASSVASGGASAATA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3041 PSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISG 3120
Cdd:COG5295 94 ASTGTGNTAGTAATVAGAASSGSATNAGASAGASAAAAAGSTAAAGGAAASTGGSSAAGGSNTATATGSSTANAATAAAG 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3121 CPSDQNVATDIG--NATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPV 3198
Cdd:COG5295 174 ATSTSASGSSSGasGAAAASAATGASAGGTASAAASASSSATGTSASVGVNAGAATGSAASAGGSASAGAASGNATTASA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3199 ISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIP 3278
Cdd:COG5295 254 SSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGGGAAALGSAGGSSGVG 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3279 VFSGcpSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNEN 3358
Cdd:COG5295 334 TASG--ASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGSGGSSTGASAGGGA 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3359 pvisgcpsdqNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNE 3438
Cdd:COG5295 412 ----------SAAGGAAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAGGGTAGAGGAANVGAATTAASAAATAAAA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3439 IPVISgcpsDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETctffvVVSDN 3518
Cdd:COG5295 482 TSSAA----IAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGST-----TAATG 552
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 47551295 3519 ENPVISGCPSDQNV-AISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAGN 3585
Cdd:COG5295 553 TNSVAVGNNTATGAnSVALGAGSVASGANSVSVGAAGAENVAAGATDTDAVNGGGAVATGDNSVAVGN 620
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2950-3029 |
1.36e-15 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 74.35 E-value: 1.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2950 DNEIPVISgCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNN-PGDDFPIGNNTVTYSANDDAGNTETCTFFVV 3028
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3029 V 3029
Cdd:pfam02494 81 V 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2542-2647 |
6.09e-15 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 73.19 E-value: 6.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2542 YISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDLILAEDPyfaLDQAYCGNQENFL 2621
Cdd:smart00042 2 TITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSD---NC-EYDYVEIYDGPSASSP---LLGRFCGSEAPPP 74
|
90 100
....*....|....*....|....*..
gi 47551295 2622 WFSTQ-NLAVLSFLSNDEGVYPGYQIY 2647
Cdd:smart00042 75 VISSSsNSLTLTFVSDSSVQKRGFSAR 101
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2014-2118 |
6.43e-15 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 73.60 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2014 LTEEGIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLgRFELgLTNGDCEAgDYIELTDENWEY--LDATYCGGSLPP 2091
Cdd:cd00041 7 ASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFE-DFDL-ESSPNCSY-DYLEIYDGPSTSspLLGRFCGSTLPP 83
|
90 100
....*....|....*....|....*..
gi 47551295 2092 VWRSRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:cd00041 84 PIISSGNSLTVRFRSDSSVTGRGFKAT 110
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3436-3515 |
1.07e-14 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 71.65 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISgCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNN-PGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3514
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTSTVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3515 V 3515
Cdd:pfam02494 81 V 81
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
2799-3630 |
2.14e-14 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 80.58 E-value: 2.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2799 SDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGC 2878
Cdd:COG3210 2 SGGLAGTTGNKTIGVDIAVTTTAATLGSNTAGTSGLNILGSGGVGTAGGIASNAGTTASTSGGSGTAGGVGNTSASTGGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2879 PSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDdfpIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISG 2958
Cdd:COG3210 82 GAAAANTAGTLETGLTSNIGGGSVNGSNSTGNGTLTTTAAS---ATTGNNTGGTTTSSTNTVTTLGGTTTGNTVLSTSGA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2959 CPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGddfpiGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFS 3038
Cdd:COG3210 159 GNNTNTNNSSSGTNIGNSIPTTGGSLNVVAANPTGVTGVGG-----ALINATAGVLANAGGGTAGGVASANSTLTGGVVA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3039 GCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVI 3118
Cdd:COG3210 234 AGTGAGVISTGGTDISSLSVAAGAGTGGAGGTGNAGNTTIGTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3119 SGCPSDQNVATDIGNATAVVIwtppTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPV 3198
Cdd:COG3210 314 GGTAAGITTTNTVGGNGDGNN----TTANSGAGLVSGGTGGNNGTTGTGAGSGLTGTGNGGGLTTAGAGTVASTVGTATA 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3199 ISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIP 3278
Cdd:COG3210 390 STGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGT 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3279 VFSGCPSDQNVTTDIGNATAVVIWT-----PPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIV 3353
Cdd:COG3210 470 GTVTNSAGNTTSATTLAGGGIGTVTtnatiSNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVS 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3354 SDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVV 3433
Cdd:COG3210 550 GGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATG 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3434 VSDNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFv 3513
Cdd:COG3210 630 GGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTI- 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3514 vvsdnenpvisgcpSDQNVAISIGNAAVvtwtpptatDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAGNTEYCTFFV 3593
Cdd:COG3210 709 --------------STGSITVTGQIGAL---------ANANGDTVTFGNLGTGATLTLNAGVTITSGNAGTLSIGLTANT 765
|
810 820 830
....*....|....*....|....*....|....*..
gi 47551295 3594 VVSDCNYTIDGAsmvSGNLSSPNYPNSSPSGLSCPIT 3630
Cdd:COG3210 766 TASGTTLTLANA---NGNTSAGATLDNAGAEISIDIT 799
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2018-2118 |
2.18e-14 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 71.65 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2018 GIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLgRFELgLTNGDCEAgDYIELTDENWEY--LDATYCGGSLPPVW-R 2094
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFT-DFDL-ESSDNCEY-DYVEIYDGPSASspLLGRFCGSEAPPPViS 77
|
90 100
....*....|....*....|....
gi 47551295 2095 SRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:smart00042 78 SSSNSLTLTFVSDSSVQKRGFSAR 101
|
|
| CUB |
pfam00431 |
CUB domain; |
1190-1285 |
2.65e-14 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 71.56 E-value: 2.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1190 TLQSPGYPADYPADLECSKILVAPEDFIIRITFTDLLLE--PGCNYDAVRLVDLQTNSAN---SLCDEVaLPYVYESTSP 1264
Cdd:pfam00431 11 SISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEdhDECGYDYVEIRDGPSASSPllgRFCGSG-IPEDIVSSSN 89
|
90 100
....*....|....*....|.
gi 47551295 1265 MLEVLFLTDATVNMRGFSATY 1285
Cdd:pfam00431 90 QMTIKFVSDASVQKRGFKATY 110
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
2961-3505 |
3.23e-14 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 79.44 E-value: 3.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2961 SDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETctffVVVSDNEIPVFSGC 3040
Cdd:COG4625 4 GGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGG----GGGGGGGGAGGGGG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3041 PSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISG 3120
Cdd:COG4625 80 GGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3121 CPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVIS 3200
Cdd:COG4625 160 AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3201 GcpsDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETctffvvvsdneipvf 3280
Cdd:COG4625 240 G---GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGG--------------- 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3281 sgcPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPV 3360
Cdd:COG4625 302 ---GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSG 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3361 ISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETctFFVVVSDNEIP 3440
Cdd:COG4625 379 GGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGA--TGGGGGGGGGA 456
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 3441 VISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGN 3505
Cdd:COG4625 457 GGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGT 521
|
|
| Hia |
COG5295 |
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ... |
2720-3349 |
3.71e-14 |
|
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain] Cd Length: 785 Bit Score: 79.43 E-value: 3.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2720 DQNVTTDIGNATAVVYWTPPTPPPDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPS 2799
Cdd:COG5295 14 LTTVASGASTTASGSSATVTSAAQSTGSAATSSGSSSAAGGSGSTSSLTAAAATAGAGSGGTSATAASSVASGGASAATA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2800 DQNVT-TDIGNATAVVIWTPPTATDNSGSQTLTS-TNNPGDDFPIGNNTVTYSASDDAGNTETCTffVVVSDNEIPVFSG 2877
Cdd:COG5295 94 ASTGTgNTAGTAATVAGAASSGSATNAGASAGASaAAAAGSTAAAGGAAASTGGSSAAGGSNTAT--ATGSSTANAATAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2878 CPSDQNVTTDI----GNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEI 2953
Cdd:COG5295 172 AGATSTSASGSssgaSGAAAASAATGASAGGTASAAASASSSATGTSASVGVNAGAATGSAASAGGSASAGAASGNATTA 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2954 PVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNE 3033
Cdd:COG5295 252 SASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGGGAAALGSAGGSSG 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3034 IPVFSGcpSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDN 3113
Cdd:COG5295 332 VGTASG--ASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGSGGSSTGASAGG 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3114 ENPVISGcpSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNpGDDFPIGNNTVTYSASDDAGNTETcTFFVVVSD 3193
Cdd:COG5295 410 GASAAGG--AAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAG-GGTAGAGGAANVGAATTAASAAAT-AAAATSSA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3194 NENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3273
Cdd:COG5295 486 AIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGSTTAATGTNSVAVGNNTATG 565
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 3274 DNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDfpIGNNTVTYSASDDA-GNTETCTF 3349
Cdd:COG5295 566 ANSVALGAGSVASGANSVSVGAAGAENVAAGATDTDAVNGGGAVATGDNSVA--VGNNAQASGANSVAlGAGATATA 640
|
|
| CUB |
pfam00431 |
CUB domain; |
2010-2118 |
4.06e-14 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 71.17 E-value: 4.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2010 CDMVLTEE-GIFTSPNSPMNYEDDMECEYTLISGEDQCIRVSFLGrFELGlTNGDCeAGDYIELTDENWEY--LDATYCG 2086
Cdd:pfam00431 1 CGGVLTDSsGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQD-FELE-DHDEC-GYDYVEIRDGPSASspLLGRFCG 77
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 2087 GSLPPVWRSRSNESSLTLYTDGVDTFRGFSAY 2118
Cdd:pfam00431 78 SGIPEDIVSSSNQMTIKFVSDASVQKRGFKAT 109
|
|
| RhsA |
COG3209 |
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction ... |
2817-3602 |
1.33e-13 |
|
Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only];
Pssm-ID: 442442 [Multi-domain] Cd Length: 1103 Bit Score: 77.87 E-value: 1.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2817 TPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVI 2896
Cdd:COG3209 2 TSLGLVGGTTGASSTLLAATNAGGGTAVTNAGSTVLLAKGGLSTAAAAGGAATLTARSASTTDVVGTLTGAGGTSAGGVT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2897 WTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVV 2976
Cdd:COG3209 82 ALGDASAAGGGYVGGAAAGGGATLTGLAAATASAGRLVSTGAGAGGTVTAATGGTLGATAGSATTGSTDGGRGGVAVTGL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2977 IWTPPTATDNSGNQTLTSTNNPGDDF-PIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGcpSDQNVTTDIGNATA 3055
Cdd:COG3209 162 AGGGASAYGLTLGGAAAGPATGVGTGaVTLATGLAGSALLALGSGAILGGLAGAYSGSATTATG--TALGTPASVAATVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3056 VVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNAT 3135
Cdd:COG3209 240 GSATGAAGAGAAVATAATTLGGTTGAGTGASGAGLDASTGTGGAGGSNAAATAGGLGGAGLGSGGAGGGGTAGGTTTAAG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3136 AVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNA 3215
Cdd:COG3209 320 TTGTAAVSGAADAGTTTTTGTGTGGTTTTVGGGGSLTLGGYGAAGGLTTSVGAGGGGSTSGSTTTVGGGGTATGSGGGSS 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3216 TAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGN 3295
Cdd:COG3209 400 TTGVGAGTTTTSTTGGDGGPATAAGALTAGGTATGTGTGGGGTTAGTDATTTTGGAGASGTLTTTGGAATGATTGGGTEA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3296 ATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGnnTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIG 3375
Cdd:COG3209 480 GTGGGTLTSGSAGATTLGTDTTLDDTLGGTTTTT--AGARGLVVTTGTTLTLGTTTTATLSATDATGTGDTTTTGTVGTG 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3376 NATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDI 3455
Cdd:COG3209 558 TSTGTGGTGTVTTTGDGTGGASTTTGTTGGTATTTTVTTTTTTSTAGTTTTTTSGYTRAGLTLTLGTGTASGLERATAST 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3456 GNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISG---CPSDQNV 3532
Cdd:COG3209 638 GSTTGGTTGTGVTTTGTTTTRATGTTGTGTGVTAGLTTLATGGTTVGGGTGTTSTATTGATTGGTETGTTvttLAGGTTT 717
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3533 AISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYsasDDAGNTEYCTFFVVVSDCNYTI 3602
Cdd:COG3209 718 RLGTTTTGGGGGTTTDGTGTGGTTGTLTTTSTTTTTTAGALTYTY---DALGRLTSETTPGGVTQGTYTT 784
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2534-2650 |
2.10e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 68.98 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2534 TFIVQDAQYISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDLILAEDPyfaLDQAY 2613
Cdd:cd00041 4 TLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSP---NC-SYDYLEIYDGPSTSSP---LLGRF 76
|
90 100 110
....*....|....*....|....*....|....*..
gi 47551295 2614 CGNQENFLWFSTQNLAVLSFLSNDEGVYPGYQIYSTF 2650
Cdd:cd00041 77 CGSTLPPPIISSGNSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1474-1583 |
3.04e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 68.59 E-value: 3.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1474 CGGNITTSGQ-PIYSPNYPANYDDNVTCVTDITNDEGC-ISIEFLMMDIDNgdyvNDTCMEDSLTITD---YNNPSLSRT 1548
Cdd:cd00041 1 CGGTLTASTSgTISSPNYPNNYPNNLNCVWTIEAPPGYrIRLTFEDFDLES----SPNCSYDYLEIYDgpsTSSPLLGRF 76
|
90 100 110
....*....|....*....|....*....|....*
gi 47551295 1549 nCGDSTPEsPWLSASGNVKVSFTSNGANSSQGYIA 1583
Cdd:cd00041 77 -CGSTLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1363-1464 |
4.54e-13 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 67.80 E-value: 4.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1363 GLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTigFLVF-INGGVPCqEGDSVTIQD--TSSGEPVISLC--QSTPADII 1437
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQ--FTDFdLESSDNC-EYDYVEIYDgpSASSPLLGRFCgsEAPPPVIS 77
|
90 100
....*....|....*....|....*..
gi 47551295 1438 SLTNEVTLTFVSDGNpaPQGTGFTLQY 1464
Cdd:smart00042 78 SSSNSLTLTFVSDSS--VQKRGFSARY 102
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
2880-3420 |
8.05e-13 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 75.20 E-value: 8.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2880 SDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGc 2959
Cdd:COG4625 3 GGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGG- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2960 psDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSG 3039
Cdd:COG4625 82 --GGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3040 CPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVIS 3119
Cdd:COG4625 160 AGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3120 GcpsDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETctffvvvSDNENPVI 3199
Cdd:COG4625 240 G---GGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGG-------GGGGGGGG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3200 SGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFpIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPV 3279
Cdd:COG4625 310 GGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGA-GGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGS 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3280 FSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFpIGNNTVTYSASDDAGNTETCTFFVIVSDNENP 3359
Cdd:COG4625 389 GGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGG-GGTGAGGGGATGGGGGGGGGAGGSGGGAGAGG 467
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47551295 3360 VISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASD 3420
Cdd:COG4625 468 GSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGTATLNGGT 528
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1827-1941 |
8.28e-13 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 67.44 E-value: 8.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1827 CSEDVT--RPGVIVSPGFgtedhygnYDGYDNNLNCIYNITNPNSTEcITVSFISFDLgQPSENCS-DYVQITDTEGGVD 1903
Cdd:cd00041 1 CGGTLTasTSGTISSPNY--------PNNYPNNLNCVWTIEAPPGYR-IRLTFEDFDL-ESSPNCSyDYLEIYDGPSTSS 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 47551295 1904 FL---YCGlpeNTTAPVFYSRSANVEVVFRTGEDERNDGFE 1941
Cdd:cd00041 71 PLlgrFCG---STLPPPIISSGNSLTVRFRSDSSVTGRGFK 108
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
996-1051 |
1.53e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 64.78 E-value: 1.53e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 996 WRIGAWSPCSVSCGNGVETRVVYCVEsEDSNVIIPSTSCDPAAEPASVQICNPGDC 1051
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQ-KGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
3517-3595 |
1.66e-12 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 65.49 E-value: 1.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3517 DNENPVISgCPSDQNVAISIGNA-AVVTWTPPTATDNSGNQTLTSTNN-PGDDFTIGNNTVTYSASDDAGNTEYCTFFVV 3594
Cdd:pfam02494 2 DTTPPTVK-CPNNIVRTVELGTStVRVFFTEPTAFDNSGQAILVSRTAqPGDFFPVGTTTVTYVAYDNSGNRASCTFTVT 80
|
.
gi 47551295 3595 V 3595
Cdd:pfam02494 81 V 81
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
2750-3586 |
2.26e-12 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 74.03 E-value: 2.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2750 TSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQT 2829
Cdd:COG3210 594 TNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGG 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2830 LTSTNNPGDDFPIGNNTVTYSASDDAGNTETctfFVVVSDNEIPVFSGCPSDQNvttdiGNATAVVIWTPPTATDNSGNQ 2909
Cdd:COG3210 674 TTGTVTSGATGGTTGTTLNAATGGTLNNAGN---TLTISTGSITVTGQIGALAN-----ANGDTVTFGNLGTGATLTLNA 745
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2910 TLTSTNNPGDDFPIGNNTVTY------SANDDAGNTETCTFFVVVSDNEIPVISGCPSDQ-------NVATDSGNATAVV 2976
Cdd:COG3210 746 GVTITSGNAGTLSIGLTANTTasgttlTLANANGNTSAGATLDNAGAEISIDITADGTITaagttaiNVTGSGGTITINT 825
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2977 IWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTetctffVVVSDNEIPVFSGCPSDQNVTTDIGNATAV 3056
Cdd:COG3210 826 ATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGS------LAATAASITVGSGGVATSTGTANAGTLTNL 899
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3057 VIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATA 3136
Cdd:COG3210 900 GTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGT 979
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3137 VVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNAT 3216
Cdd:COG3210 980 SANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAA 1059
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3217 AVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNA 3296
Cdd:COG3210 1060 ALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEA 1139
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3297 TAVVIwTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGN 3376
Cdd:COG3210 1140 AGAGT-LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTT 1218
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3377 ATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDIG 3456
Cdd:COG3210 1219 TTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSATSAGG 1298
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3457 NATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVAISI 3536
Cdd:COG3210 1299 SLDTTGNTAGANGATVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTAANTGLNGGNGATDSAAGAGSGGAAGSLAATA 1378
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 47551295 3537 GNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAGNT 3586
Cdd:COG3210 1379 GAGTVLTGAGNNTGAEGTNAGRDGGVTTSGTGVGNNGGVSGTTVAGTTGS 1428
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
3105-3601 |
7.02e-12 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 72.12 E-value: 7.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3105 TFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTET 3184
Cdd:COG4625 3 GGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3185 CTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTE 3264
Cdd:COG4625 83 GGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3265 TCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNT 3344
Cdd:COG4625 163 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3345 ETCTFFVIVSDNENPVISGcpsdqnvTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGN 3424
Cdd:COG4625 243 GGGGGAGGGGGGGGGNGGG-------GGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGG 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3425 TETCTFFVVVSDNEIPVISGcpsdQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAG 3504
Cdd:COG4625 316 GGGGGGGGGGGGGGGGGGAG----GGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGG 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3505 NTetcTFFVVVSDNENPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAG 3584
Cdd:COG4625 392 GG---GGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGG 468
|
490
....*....|....*..
gi 47551295 3585 NTEYCTFFVVVSDCNYT 3601
Cdd:COG4625 469 SGSGAGTLTLTGNNTYT 485
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1956-2007 |
7.84e-12 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.86 E-value: 7.84e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1956 AGNFSECSVTCGEGVEYRRVGCTRLSDSQLVTDDFCNDQ-RPSDSRPCSLPEC 2007
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1116-1171 |
1.34e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.34e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 1116 YEATPWSACSVTCALGVQTRGVSCVTRKGSGVVIDEmDCSNMTRPSESRECYLDPC 1171
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDS-ECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
757-810 |
1.35e-11 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 62.09 E-value: 1.35e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 757 YVATSFGDCSVSCGPGLRSRSIFCVSE-SNQVVDDSFCAGLVRQVESESCNLTPC 810
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKgGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1485-1583 |
1.45e-11 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 63.56 E-value: 1.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1485 IYSPNYPANYDDNVTCVTDITNDEGC-ISIEFLMMDIDNgdyvNDTCMEDSLTITD---YNNPSLSRTnCGDSTPESPWL 1560
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGYrIELQFTDFDLES----SDNCEYDYVEIYDgpsASSPLLGRF-CGSEAPPPVIS 77
|
90 100
....*....|....*....|...
gi 47551295 1561 SASGNVKVSFTSNGANSSQGYIA 1583
Cdd:smart00042 78 SSSNSLTLTFVSDSSVQKRGFSA 100
|
|
| ZnMc_salivary_gland_MPs |
cd04272 |
Zinc-dependent metalloprotease, salivary_gland_MPs. Metalloproteases secreted by the salivary ... |
218-410 |
1.54e-11 |
|
Zinc-dependent metalloprotease, salivary_gland_MPs. Metalloproteases secreted by the salivary glands of arthropods.
Pssm-ID: 239800 Cd Length: 220 Bit Score: 66.99 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 218 YIETSVVADSKmFDYHGDDTEFYI--FTILNQVAGLFRDKTLSADLRLLVTSITIFTAPQSNLDL------TDELSHSLK 289
Cdd:cd04272 2 YPELFVVVDYD-HQSEFFSNEQLIryLAVMVNAANLRYRDLKSPRIRLLLVGITISKDPDFEPYIhpinygYIDAAETLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 290 NFCEWQKDEK----SDISILLTRRDL---EIGGNDAVTGKSKDIGGACDpSRRCIIAQDHGPSGT-IFTLAHEIGHSLGI 361
Cdd:cd04272 81 NFNEYVKKKRdyfnPDVVFLVTGLDMstySGGSLQTGTGGYAYVGGACT-ENRVAMGEDTPGSYYgVYTMTHELAHLLGA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 47551295 362 YHDDSE-----------SGC-ANNKNIMATDNsGGSEAFQWSLCSNKDLLQFLSTSDSVCL 410
Cdd:cd04272 160 PHDGSPppswvkghpgsLDCpWDDGYIMSYVV-NGERQYRFSQCSQRQIRNVFRRLGASCL 219
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
2750-3258 |
2.67e-11 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 70.19 E-value: 2.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2750 TSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPSDQNVTTDIGNATAVV--IWTPPTATDNSGS 2827
Cdd:COG4625 30 GGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGTGGVGggGGGGGGGGGGGGG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2828 QTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSG 2907
Cdd:COG4625 110 GGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2908 NQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGcPSDQNVATDSGNATAVVIWTPPTATDNS 2987
Cdd:COG4625 190 GGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGG-GGGGGGGAGGGGGGGGGNGGGGGAGGGG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2988 GNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNeipvfsgcpSDQNVTTDIGNATAVVIWTPPTATDN 3067
Cdd:COG4625 269 GGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGG---------GGGGGGGGGGGGGGGGGGGGAGGGGG 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3068 SGSQTLTSTNNPGDDFpIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATD 3147
Cdd:COG4625 340 SGGAGAGGGGAGGGGA-GGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGG 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3148 NSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDqNVTTDIGNATAVVIWTPPTAT 3227
Cdd:COG4625 419 AAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTL-TLTGNNTYTGTTTVNGGGNYT 497
|
490 500 510
....*....|....*....|....*....|.
gi 47551295 3228 DNSGSQTLTSTNNPGDDFPIGNNTVTYSASD 3258
Cdd:COG4625 498 QSAGSTLAVEVDAANSDRLVVTGTATLNGGT 528
|
|
| HYR |
pfam02494 |
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin ... |
2713-2786 |
9.44e-11 |
|
HYR domain; This domain is known as the HYR (Hyalin Repeat) domain, after the protein hyalin that is composed exclusively of this repeat. This domain probably corresponds to a new superfamily in the immunoglobulin fold. The function of this domain is uncertain it may be involved in cell adhesion.
Pssm-ID: 460572 [Multi-domain] Cd Length: 81 Bit Score: 60.48 E-value: 9.44e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 2713 PVEGCPSDQNVTTDIGNATAVVYWTPPTPP--PDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVV 2786
Cdd:pfam02494 6 PTVKCPNNIVRTVELGTSTVRVFFTEPTAFdnSGQAILVSRTAQPGDFFPVGTTTVTYVAYDNSGNRASCTFTVTV 81
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1835-1941 |
1.12e-10 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 60.87 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1835 GVIVSPGFGtedhygnyDGYDNNLNCIYNITNPNSTEcITVSFISFDLgQPSENCS-DYVQITDTEGGVDFL---YCGlp 1910
Cdd:smart00042 1 GTITSPNYP--------QSYPNNLDCVWTIRAPPGYR-IELQFTDFDL-ESSDNCEyDYVEIYDGPSASSPLlgrFCG-- 68
|
90 100 110
....*....|....*....|....*....|.
gi 47551295 1911 ENTTAPVFYSRSANVEVVFRTGEDERNDGFE 1941
Cdd:smart00042 69 SEAPPPVISSSSNSLTLTFVSDSSVQKRGFS 99
|
|
| CUB |
pfam00431 |
CUB domain; |
1353-1464 |
1.35e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 61.16 E-value: 1.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1353 CGENILRlAPGLVTSPRFPRSYPVNVTCVNTIRAPPGNVISFTigFLVF-INGGVPCQeGDSVTIQDTSSGEPVI--SLC 1429
Cdd:pfam00431 1 CGGVLTD-SSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLT--FQDFeLEDHDECG-YDYVEIRDGPSASSPLlgRFC 76
|
90 100 110
....*....|....*....|....*....|....*.
gi 47551295 1430 QST-PADIISLTNEVTLTFVSDGNpaPQGTGFTLQY 1464
Cdd:pfam00431 77 GSGiPEDIVSSSNQMTIKFVSDAS--VQKRGFKATY 110
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1772-1824 |
1.46e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 59.00 E-value: 1.46e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1772 PGPWSECSLSCDGGVRTRDVFCMNLATRQTDREALCEGSPFYEPMEECNTEEC 1824
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| CUB |
pfam00431 |
CUB domain; |
1474-1581 |
4.04e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 59.62 E-value: 4.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1474 CGGNITTSGQPIYSPNYPANYDDNVTCVTDITNDEG-CISIEFLMMDIdngdYVNDTCMEDSLTITD---YNNPSLSRTn 1549
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGfRVKLTFQDFEL----EDHDECGYDYVEIRDgpsASSPLLGRF- 75
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 1550 CGDSTPEsPWLSASGNVKVSFTSNGANSSQGY 1581
Cdd:pfam00431 76 CGSGIPE-DIVSSSNQMTIKFVSDASVQKRGF 106
|
|
| CUB |
pfam00431 |
CUB domain; |
2532-2647 |
4.16e-10 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 59.62 E-value: 4.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2532 CDTFIVQDAQYISSPNYPQPYDNDGNCTTIIVAPEGMCINLFFISFELQEPDmyaGCvASDFLAITDlilAEDPYFALDQ 2611
Cdd:pfam00431 1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHD---EC-GYDYVEIRD---GPSASSPLLG 73
|
90 100 110
....*....|....*....|....*....|....*...
gi 47551295 2612 AYCGNQ--ENFlwFSTQNLAVLSFLSNDEGVYPGYQIY 2647
Cdd:pfam00431 74 RFCGSGipEDI--VSSSNQMTIKFVSDASVQKRGFKAT 109
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1297-1347 |
5.84e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.46 E-value: 5.84e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1297 TGEWGECSVTCGVGTESRDVTCVEE--GVEVDVSTCAGLPVPPATRSCTQEDC 1347
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKggGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
2808-3404 |
5.87e-10 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 65.23 E-value: 5.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2808 GNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTD 2887
Cdd:COG4935 1 GAAGGAGSTTGLAAAVLAAAAGTGSAATAEGGAASTATSAAVAGASAAAAAATAVGAGASSLAASAAAAAAAASGAAAGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2888 IGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVAT 2967
Cdd:COG4935 81 VDAAPAAATVVGAALGVVAVAGAGLAATASGAAAGAVAAAANGNTGAGPGSGGTGGGSGGAGAAAAAAALSAAGAAVGVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2968 DSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVT 3047
Cdd:COG4935 161 AVAGAAGGGGGVGVAAAVGVVLGAGLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAAAAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3048 TDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNV 3127
Cdd:COG4935 241 AAGVGGLGAAATAAAADGGGGGGAGAAGAGGSAGAAAGGAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAASAGSGG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3128 ATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQN 3207
Cdd:COG4935 321 GGGSAAAAGAAAAAAAAAAGAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAGAAAAGG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3208 VTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDfPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQ 3287
Cdd:COG4935 401 VASAAGAVGAGTAAGASATAAVSTGAASGSSTTSSTG-TTATATGLGGGADAGSTSTGTGSAAGAAGGTTTATSGLASST 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3288 NVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDA------GNTETCTFFVIVSDNENPvi 3361
Cdd:COG4935 480 TAAAAAAAAGLATTAAVAAGAAGAAAAAATAASVGGATGAAGTTNSTATFSNTTdvaipdNGPAGVTSTITVSGGGAV-- 557
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 3362 sgcpSDQNVTTDI--------------GNATAVVIWTPPTATDNSGNQTLTSTNNPG 3404
Cdd:COG4935 558 ----EDVTVTVDIthtyrgdlvitlisPDGTTVVLKNRSGGSADNINATFDVANFSG 610
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2303-2355 |
7.68e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 57.08 E-value: 7.68e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2303 ASNFSECSVSCGEGFRTRDVLCTRLETGENVSRDNCDENEILPNIEPCNEQPC 2355
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2477-2529 |
8.72e-10 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 56.69 E-value: 8.72e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 2477 TGPYSEeCSATCGEGVVYRNVTCQDLMTRAVVNDSLCSEL-RPSEIKPCRREPC 2529
Cdd:pfam19030 3 AGPWGE-CSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQkKPPETQSCNLKPC 55
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
2724-3253 |
1.79e-09 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 63.69 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2724 TTDIGNATAVVYWTPPTPPPDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPSDQNV 2803
Cdd:COG4935 20 AAGTGSAATAEGGAASTATSAAVAGASAAAAAATAVGAGASSLAASAAAAAAAASGAAAGAVDAAPAAATVVGAALGVVA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2804 TTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGC----- 2878
Cdd:COG4935 100 VAGAGLAATASGAAAGAVAAAANGNTGAGPGSGGTGGGSGGAGAAAAAAALSAAGAAVGVAAVAGAAGGGGGVGVaaavg 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2879 ------PSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNE 2952
Cdd:COG4935 180 vvlgagLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAAAAAAAGVGGLGAAATAAAADGG 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2953 IPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDN 3032
Cdd:COG4935 260 GGGGAGAAGAGGSAGAAAGGAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAASAGSGGGGGSAAAAGAAAAAAAAAA 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3033 EIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSD 3112
Cdd:COG4935 340 GAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAGAAAAGGVASAAGAVGAGTAAGASAT 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3113 NENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3192
Cdd:COG4935 420 AAVSTGAASGSSTTSSTGTTATATGLGGGADAGSTSTGTGSAAGAAGGTTTATSGLASSTTAAAAAAAAGLATTAAVAAG 499
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47551295 3193 DNENPVISGCPSDQNVTTDIG---NATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVT 3253
Cdd:COG4935 500 AAGAAAAAATAASVGGATGAAgttNSTATFSNTTDVAIPDNGPAGVTSTITVSGGGAVEDVTVT 563
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
2889-3485 |
2.00e-09 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 63.69 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2889 GNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATD 2968
Cdd:COG4935 1 GAAGGAGSTTGLAAAVLAAAAGTGSAATAEGGAASTATSAAVAGASAAAAAATAVGAGASSLAASAAAAAAAASGAAAGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2969 SGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTT 3048
Cdd:COG4935 81 VDAAPAAATVVGAALGVVAVAGAGLAATASGAAAGAVAAAANGNTGAGPGSGGTGGGSGGAGAAAAAAALSAAGAAVGVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3049 DIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVA 3128
Cdd:COG4935 161 AVAGAAGGGGGVGVAAAVGVVLGAGLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAAAAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3129 TDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNV 3208
Cdd:COG4935 241 AAGVGGLGAAATAAAADGGGGGGAGAAGAGGSAGAAAGGAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAASAGSGG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3209 TTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQN 3288
Cdd:COG4935 321 GGGSAAAAGAAAAAAAAAAGAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAGAAAAGG 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3289 VTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDfPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQ 3368
Cdd:COG4935 401 VASAAGAVGAGTAAGASATAAVSTGAASGSSTTSSTG-TTATATGLGGGADAGSTSTGTGSAAGAAGGTTTATSGLASST 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3369 NVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDA------GNTETCTFFVVVSDNEIPvi 3442
Cdd:COG4935 480 TAAAAAAAAGLATTAAVAAGAAGAAAAAATAASVGGATGAAGTTNSTATFSNTTdvaipdNGPAGVTSTITVSGGGAV-- 557
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 3443 sgcpSDQNVATDI--------------GNATAVVTWTPPTATDNSVNQTLTSTNNPG 3485
Cdd:COG4935 558 ----EDVTVTVDIthtyrgdlvitlisPDGTTVVLKNRSGGSADNINATFDVANFSG 610
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
3047-3576 |
2.35e-09 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 63.30 E-value: 2.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3047 TTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNeNPVISGCPSDQN 3126
Cdd:COG4935 20 AAGTGSAATAEGGAASTATSAAVAGASAAAAAATAVGAGASSLAASAAAAAAAASGAAAGAVDAAPA-AATVVGAALGVV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3127 VATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGC---- 3202
Cdd:COG4935 99 AVAGAGLAATASGAAAGAVAAAANGNTGAGPGSGGTGGGSGGAGAAAAAAALSAAGAAVGVAAVAGAAGGGGGVGVaaav 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3203 -------PSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDN 3275
Cdd:COG4935 179 gvvlgagLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAAAAAAAGVGGLGAAATAAAADG 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3276 EIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSD 3355
Cdd:COG4935 259 GGGGGAGAAGAGGSAGAAAGGAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAASAGSGGGGGSAAAAGAAAAAAAAA 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3356 NENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3435
Cdd:COG4935 339 AGAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAGAAAAGGVASAAGAVGAGTAAGASA 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3436 DNEIPVISGCPSDQNVATdIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVV 3515
Cdd:COG4935 419 TAAVSTGAASGSSTTSST-GTTATATGLGGGADAGSTSTGTGSAAGAAGGTTTATSGLASSTTAAAAAAAAGLATTAAVA 497
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 47551295 3516 SDNE-----NPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVT 3576
Cdd:COG4935 498 AGAAgaaaaAATAASVGGATGAAGTTNSTATFSNTTDVAIPDNGPAGVTSTITVSGGGAVEDVTVT 563
|
|
| ZnMc |
cd00203 |
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
299-384 |
2.88e-09 |
|
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease.
Pssm-ID: 238124 [Multi-domain] Cd Length: 167 Bit Score: 59.07 E-value: 2.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 299 KSDISILLTRRDLEIGGndavTGKSKdIGGACDPSRRCIIAQDHGPSGTIF--TLAHEIGHSLGIYHDDSESGCANNKNI 376
Cdd:cd00203 51 KADIAILVTRQDFDGGT----GGWAY-LGRVCDSLRGVGVLQDNQSGTKEGaqTIAHELGHALGFYHDHDRKDRDDYPTI 125
|
....*...
gi 47551295 377 MATDNSGG 384
Cdd:cd00203 126 DDTLNAED 133
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2658-2712 |
3.17e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 55.15 E-value: 3.17e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 2658 YLVTPFEECSVTCGLGEVRRDIFCVDRYTNDTVSDDQCAGDVRPIEFLPCYIDNC 2712
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1056-1112 |
4.21e-09 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 54.77 E-value: 4.21e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 1056 WVSENFGDCSVTCGDGVRVRNVLCyaIAGGNFEPVVGSLCNPLLEPPSEEICDLEDC 1112
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQC--VQKGGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
581-627 |
1.06e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 53.61 E-value: 1.06e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 581 GQCSVTCGTGSETRVVNCVDSESN-IVDDSLCTD-ERPPEVIECASTPC 627
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
3086-3631 |
1.98e-08 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 60.22 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3086 GNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNP----- 3160
Cdd:COG4935 1 GAAGGAGSTTGLAAAVLAAAAGTGSAATAEGGAASTATSAAVAGASAAAAAATAVGAGASSLAASAAAAAAAASGaaaga 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3161 GDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNN 3240
Cdd:COG4935 81 VDAAPAAATVVGAALGVVAVAGAGLAATASGAAAGAVAAAANGNTGAGPGSGGTGGGSGGAGAAAAAAALSAAGAAVGVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3241 PGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTN 3320
Cdd:COG4935 161 AVAGAAGGGGGVGVAAAVGVVLGAGLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAAAAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3321 NPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTST 3400
Cdd:COG4935 241 AAGVGGLGAAATAAAADGGGGGGAGAAGAGGSAGAAAGGAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAASAGSGG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3401 NNpGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTS 3480
Cdd:COG4935 321 GG-GSAAAAGAAAAAAAAAAGAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAGAAAAG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3481 TNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDN--ENPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTL 3558
Cdd:COG4935 400 GVASAAGAVGAGTAAGASATAAVSTGAASGSSTTSSTGttATATGLGGGADAGSTSTGTGSAAGAAGGTTTATSGLASST 479
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47551295 3559 TSTNNPGDDFTIGNNTVTYSASDDAGNTEYCTFFVVVSDCNYTIDGASMVSGNLSSPnYPNSSPSGLSCPITF 3631
Cdd:COG4935 480 TAAAAAAAAGLATTAAVAAGAAGAAAAAATAASVGGATGAAGTTNSTATFSNTTDVA-IPDNGPAGVTSTITV 551
|
|
| COG4625 |
COG4625 |
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ... |
2722-3181 |
6.43e-08 |
|
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain] Cd Length: 900 Bit Score: 59.02 E-value: 6.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2722 NVTTDIGNATAVVYWTPPTPPPDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGcpsdq 2801
Cdd:COG4625 73 GAGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGG----- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2802 nVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSD 2881
Cdd:COG4625 148 -GAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGG 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2882 QNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGcps 2961
Cdd:COG4625 227 GGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGG--- 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2962 DQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCP 3041
Cdd:COG4625 304 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAG 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3042 SDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTEtcTFFVIVSDNENPVISGC 3121
Cdd:COG4625 384 GGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGG--ATGGGGGGGGGAGGSGG 461
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3122 PSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGN 3181
Cdd:COG4625 462 GAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGT 521
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
2131-2182 |
7.72e-08 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 51.30 E-value: 7.72e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 2131 VGEYGECDVSCGSGVQTREVECTDLTTQESVAMGLCTD-PMPPSTTECNEEPC 2182
Cdd:pfam19030 3 AGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAqKKPPETQSCNLKPC 55
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
3144-3615 |
1.18e-07 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 57.70 E-value: 1.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3144 TATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTP 3223
Cdd:COG3401 16 SAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3224 PTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFfVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWT 3303
Cdd:COG3401 96 TLTGSGSVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGT-YALGAGLYGVDGANASGTTASSVAGAGVVVSPDT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3304 PPTATDNSGSQTLTSTNNPGDDFPIGNNTVTY---SASDDAGNTETCTFFVIVSDNENPVIsgcPSdqNVTTDIGNATAV 3380
Cdd:COG3401 175 SATAAVATTSLTVTSTTLVDGGGDIEPGTTYYyrvAATDTGGESAPSNEVSVTTPTTPPSA---PT--GLTATADTPGSV 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3381 VI-WTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTY----------------SASDDAGNTETCTFFV-VVSDNEIPvi 3442
Cdd:COG3401 250 TLsWDPVTESDATGYRVYRSNSGDGPFTKVATVTTTSytdtgltngttyyyrvTAVDAAGNESAPSNVVsVTTDLTPP-- 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3443 sgcPSDQNV-ATDIGNATAVVTWTPPTATD---------NSVNQTL-----TSTNNPGDDFPIGNNTVTY---SASDDAG 3504
Cdd:COG3401 328 ---AAPSGLtATAVGSSSITLSWTASSDADvtgynvyrsTSGGGTYtkiaeTVTTTSYTDTGLTPGTTYYykvTAVDAAG 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3505 NTETCTFFVVVSDNENPVIsgcPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAG 3584
Cdd:COG3401 405 NESAPSEEVSATTASAASG---ESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATT 481
|
490 500 510
....*....|....*....|....*....|.
gi 47551295 3585 NTEYCTFFVVVSDCNYTIDGASMVSGNLSSP 3615
Cdd:COG3401 482 TDTTTANLSVTTGSLVGGSGASSVTNSVSVI 512
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
2368-2467 |
1.58e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 52.41 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2368 FESPGFPSEYPENLQCVYDFYNINDECWRITAYYFDLQdkENDQCR-DRFFVEDvGFAGREPYIA--CGQEF-SPVLSFS 2443
Cdd:cd00041 13 ISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLE--SSPNCSyDYLEIYD-GPSTSSPLLGrfCGSTLpPPIISSG 89
|
90 100
....*....|....*....|....
gi 47551295 2444 RTIRITFFSDDKYSGRGFSAVARS 2467
Cdd:cd00041 90 NSLTVRFRSDSSVTGRGFKATYSA 113
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
1595-1648 |
1.66e-07 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 50.53 E-value: 1.66e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 1595 WVPLPFGNCSEICGVGNRTRELECVNALTNELTGRDECPDEE-PPTTEPCFIEEC 1648
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKkPPETQSCNLKPC 55
|
|
| Reprolysin_5 |
pfam13688 |
Metallo-peptidase family M12; |
223-389 |
1.95e-07 |
|
Metallo-peptidase family M12;
Pssm-ID: 372673 Cd Length: 191 Bit Score: 54.35 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 223 VVADSKMFDYH-GDDTEFYIFTILNQVAGLFRDKTlsaDLRLLVTSITIFT-------APQSNLDLTDELShSLKNFCEW 294
Cdd:pfam13688 9 VAADCSYVAAFgGDAAQANIINMVNTASNVYERDF---NISLGLVNLTISDstcpytpPACSTGDSSDRLS-EFQDFSAW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 295 QKDEKSDISILLTRRDLEIGGNDAV-TGKSKDIGGACDPSRRcIIAQDHGPSGTIFTLAHEIGHSLGIYHD---DSESGC 370
Cdd:pfam13688 85 RGTQNDDLAYLFLMTNCSGGGLAWLgQLCNSGSAGSVSTRVS-GNNVVVSTATEWQVFAHEIGHNFGAVHDcdsSTSSQC 163
|
170 180
....*....|....*....|....*...
gi 47551295 371 ---------ANNKNIMATDNSGGSEAFQ 389
Cdd:pfam13688 164 cppsnstcpAGGRYIMNPSSSPNSTDFS 191
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
2368-2463 |
4.40e-07 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 50.85 E-value: 4.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2368 FESPGFPSEYPENLQCVYDFYNINDEcwRITAY--YFDLQDkeNDQCR-DRFFVEDVGFAGREPY-IACGQEFSPVL--S 2441
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGY--RIELQftDFDLES--SDNCEyDYVEIYDGPSASSPLLgRFCGSEAPPPVisS 78
|
90 100
....*....|....*....|..
gi 47551295 2442 FSRTIRITFFSDDKYSGRGFSA 2463
Cdd:smart00042 79 SSNSLTLTFVSDSSVQKRGFSA 100
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
1651-1758 |
6.23e-07 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 50.49 E-value: 6.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1651 CDVSITAGNSQ-ITFPMSNDYYLYNDECTLTITNENGCM-MLFFTSLDIDEGlgDTCYNDYLMIFDPINVYANE--PYCG 1726
Cdd:cd00041 1 CGGTLTASTSGtISSPNYPNNYPNNLNCVWTIEAPPGYRiRLTFEDFDLESS--PNCSYDYLEIYDGPSTSSPLlgRFCG 78
|
90 100 110
....*....|....*....|....*....|..
gi 47551295 1727 NAINTmPYKTIGNTVELTLRTEDAERFKSFEV 1758
Cdd:cd00041 79 STLPP-PIISSGNSLTVRFRSDSSVTGRGFKA 109
|
|
| YjdB |
COG5492 |
Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction ... |
2961-3588 |
1.75e-06 |
|
Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction only];
Pssm-ID: 444243 [Multi-domain] Cd Length: 613 Bit Score: 53.93 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2961 SDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGC 3040
Cdd:COG5492 9 GLGKGVLTVTAVNTGDNDSTAGVTSSSVTANLSVLASNDTSTTSSVASVVSTAGSGGTANTSSTVAVSGAALAAGAVSTV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3041 PSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISG 3120
Cdd:COG5492 89 GVDATTVAQTVATASLEAGGVSSTGTGTATTETVGTAATADAQIVKAASTGSGSVTAAVAVGSVGVASAGTSVTTTVATA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3121 CPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVIS 3200
Cdd:COG5492 169 TSASLVSTLVVTSVGLTTASGSLNTVVVTSVVGNGATDASTASAVVAAVTAVTSAGSLTSAASVTTAGDDGTGVVATTVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3201 GCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVF 3280
Cdd:COG5492 249 TTISTSSSTTLTVTGATSSASTLGSGSTTSTNTVTAGVGDTGVSVAVASSSAATTSAVVGTLSSSGGGGGVVTAAATTGV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3281 SGCPSDQNVTTDIGNATAVVIWTPPTATDNSG-SQTLTSTNNPGDdfpIGNNTVTYSASDDAgntetctffvIVSDNENP 3359
Cdd:COG5492 329 TVVTASSVATTVDVVPVTGVTLNPTSVTLAVGqTLTLTATVTPAN---ATNKNVTWSSSDPS----------VATVDSNG 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3360 VISGCPSDQ---NVTTDIGNATAVViwtpptatdnsgnqTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSD 3436
Cdd:COG5492 396 LVTAVAAGTatiTATTKDGGKTATC--------------TVTVTAAGSTGTVVVVSLAATSAVSASVVLTPAGTVNAGAS 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3437 NEIPVISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVS 3516
Cdd:COG5492 462 TASLNVNATDGVSTTVGVANVVSAVTVTASVAEVATSVGGGATVTVTVSTAATVTVTVGVKSTGIAVAGSTGILAGIVLS 541
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 47551295 3517 DNENPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAGNTEY 3588
Cdd:COG5492 542 GSAKGDVAGGATLVDAGTADVGGTTSTTTSVTDASVVSLTGSTSSTGVGVGGTTATGTAVAALVTGTGATVV 613
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
876-922 |
2.16e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.45 E-value: 2.16e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 47551295 876 YVVGEYGQCSATCGFGIQQRSVACVDLDnDNQTVSNTQCSEAAPPSA 922
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQKG-GGSIVPDSECSAQKKPPE 46
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
704-751 |
2.56e-06 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 47.06 E-value: 2.56e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 47551295 704 GACSVTCGEGVQELTVFCQSLAGM-VVDDFNCASLQRPASSQICTQEIC 751
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGsIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1297-1348 |
3.06e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 46.81 E-value: 3.06e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 1297 TGEWGECSVTCGVGTESRDVTCVEEGVEVDVSTCAGLpvPPATRSCTQEDCP 1348
Cdd:smart00209 4 WSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGE--DVETRACNEQPCP 53
|
|
| Reprolysin_4 |
pfam13583 |
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the ... |
223-394 |
3.19e-06 |
|
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the characteriztic binding motif HExxGHxxGxxH of Reprolysin-like peptidases of family M12B.
Pssm-ID: 404471 Cd Length: 203 Bit Score: 50.70 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 223 VVADSKMFDYHGDDTE-----FYIFTILNQVAGlfrdKTLSADLRLLVTSITIFTAPQSN----LDLTDELSHSLKNFCE 293
Cdd:pfam13583 9 VATDCTYSASFGSVDElraniNATVTTANEVYG----RDFNVSLALISDRDVIYTDSSTDsfnaDCSGGDLGNWRLATLT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 294 WQKDEKSDISILLTRRDLEIGGNDAVTGkskdIGGACDPSRRCIIAQDHGPSGTIF-TLAHEIGHSLGIYHDDSESGC-- 370
Cdd:pfam13583 85 SWRDSLNYDLAYLTLMTGPSGQNVGVAW----VGALCSSARQNAKASGVARSRDEWdIFAHEIGHTFGAVHDCSSQGEgl 160
|
170 180 190
....*....|....*....|....*....|
gi 47551295 371 ------ANNKNIMATDNSGGSEAFqwSLCS 394
Cdd:pfam13583 161 ssstedGSGQTIMSYASTASQTAF--SPCT 188
|
|
| YjdB |
COG5492 |
Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction ... |
3042-3630 |
3.64e-06 |
|
Uncharacterized conserved protein YjdB, contains Ig-like domain [General function prediction only];
Pssm-ID: 444243 [Multi-domain] Cd Length: 613 Bit Score: 53.16 E-value: 3.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3042 SDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGC 3121
Cdd:COG5492 9 GLGKGVLTVTAVNTGDNDSTAGVTSSSVTANLSVLASNDTSTTSSVASVVSTAGSGGTANTSSTVAVSGAALAAGAVSTV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3122 PSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISG 3201
Cdd:COG5492 89 GVDATTVAQTVATASLEAGGVSSTGTGTATTETVGTAATADAQIVKAASTGSGSVTAAVAVGSVGVASAGTSVTTTVATA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3202 CPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFS 3281
Cdd:COG5492 169 TSASLVSTLVVTSVGLTTASGSLNTVVVTSVVGNGATDASTASAVVAAVTAVTSAGSLTSAASVTTAGDDGTGVVATTVT 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3282 GCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVI 3361
Cdd:COG5492 249 TTISTSSSTTLTVTGATSSASTLGSGSTTSTNTVTAGVGDTGVSVAVASSSAATTSAVVGTLSSSGGGGGVVTAAATTGV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3362 SGCPSDQNVTTDIGNATAVVIWTPPTATDNSG-NQTLTSTNNPGDdfpIGNNTVTYSASDdagnTETCTffvVVSDNEIP 3440
Cdd:COG5492 329 TVVTASSVATTVDVVPVTGVTLNPTSVTLAVGqTLTLTATVTPAN---ATNKNVTWSSSD----PSVAT---VDSNGLVT 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3441 VISGCPSDQNVATDIGN--ATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDN 3518
Cdd:COG5492 399 AVAAGTATITATTKDGGktATCTVTVTAAGSTGTVVVVSLAATSAVSASVVLTPAGTVNAGASTASLNVNATDGVSTTVG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3519 ENPVISGcPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFTIGNNTVTYSASDDAGNTEYCTFFVVVSDC 3598
Cdd:COG5492 479 VANVVSA-VTVTASVAEVATSVGGGATVTVTVSTAATVTVTVGVKSTGIAVAGSTGILAGIVLSGSAKGDVAGGATLVDA 557
|
570 580 590
....*....|....*....|....*....|..
gi 47551295 3599 NYTIDGASMVSGNLSSPNYPNSSPSGLSCPIT 3630
Cdd:COG5492 558 GTADVGGTTSTTTSVTDASVVSLTGSTSSTGV 589
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1119-1172 |
5.84e-06 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 46.04 E-value: 5.84e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 1119 TPWSACSVTCALGVQTRGVSCVTRKGSGvviDEMDCSnmTRPSESRECYLDPCP 1172
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQN---GGGPCT--GEDVETRACNEQPCP 53
|
|
| Reprolysin_3 |
pfam13582 |
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the ... |
240-364 |
9.22e-06 |
|
Metallo-peptidase family M12B Reprolysin-like; This zinc-binding metallo-peptidase has the characteriztic binding motif HExxGHxxGxxH of Reprolysin-like peptidases of family M12B.
Pssm-ID: 463926 [Multi-domain] Cd Length: 122 Bit Score: 47.75 E-value: 9.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 240 YIFTILNQVAGLFRDKTlsaDLRLLVTSITIFTaPQSNLDLTDELSHSLKNFCEWQKDEKS----DISILLTRRDLEIGG 315
Cdd:pfam13582 2 RIVSLVNRANTIYERDL---GIRLQLAAIIITT-SADTPYTSSDALEILDELQEVNDTRIGqygyDLGHLFTGRDGGGGG 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 316 NDAVtgkskdIGGACDPSRRCIIAQDHGPSG--TIFTLAHEIGHSLGIYHD 364
Cdd:pfam13582 78 GIAY------VGGVCNSGSKFGVNSGSGPVGdtGADTFAHEIGHNFGLNHT 122
|
|
| COG4935 |
COG4935 |
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases ... |
2719-3161 |
1.60e-05 |
|
Regulatory P domain of the subtilisin-like proprotein convertases and other proteases [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443962 [Multi-domain] Cd Length: 641 Bit Score: 50.98 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2719 SDQNVTTDIGNATAVVYWTPPTPPPDYSVNKTSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCP 2798
Cdd:COG4935 158 GVAAVAGAAGGGGGVGVAAAVGVVLGAGLVADGGNGGGGAVAGGAAGGGGGGGGGGGLGGAAGGGGAGLAAAGGGGGGAA 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2799 SDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDfpiGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGC 2878
Cdd:COG4935 238 AAAAAGVGGLGAAATAAAADGGGGGGAGAAGAGGSAGAAAG---GAGAGVVGAAAGGGDAALGGAVGAAGTGNAAAAAAA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2879 PSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISG 2958
Cdd:COG4935 315 SAGSGGGGGSAAAAGAAAAAAAAAAGAAAGVSGAASVVAGASGGGAGTAAAAGGGAAAAAAGGAAAAGAAAGAAAGAAAG 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2959 CPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDfPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFS 3038
Cdd:COG4935 395 AAAAGGVASAAGAVGAGTAAGASATAAVSTGAASGSSTTSSTG-TTATATGLGGGADAGSTSTGTGSAAGAAGGTTTATS 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3039 GCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPIGNNTVTYSASDDA------GNTETCTFFVIVSD 3112
Cdd:COG4935 474 GLASSTTAAAAAAAAGLATTAAVAAGAAGAAAAAATAASVGGATGAAGTTNSTATFSNTTdvaipdNGPAGVTSTITVSG 553
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47551295 3113 NENPvisgcpSDQNVATDI--------------GNATAVVIWTPPTATDNSGNQTLTSTNNPG 3161
Cdd:COG4935 554 GGAV------EDVTVTVDIthtyrgdlvitlisPDGTTVVLKNRSGGSADNINATFDVANFSG 610
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
995-1051 |
2.13e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 44.50 E-value: 2.13e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 995 VWRIGAWSPCSVSCGNGVETRVVYCVeseDSNVIIPSTSCDPAAEpaSVQICNPGDC 1051
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCC---SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
816-871 |
3.06e-05 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 43.98 E-value: 3.06e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 816 YEVQPFPECTLPCGSQSFVRVVLCR-SSEGGVVSSTNCVGAglEAPPTTFDCNLEPC 871
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVqKGGGSIVPDSECSAQ--KKPPETQSCNLKPC 55
|
|
| CUB |
pfam00431 |
CUB domain; |
1827-1940 |
3.93e-05 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 45.36 E-value: 3.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1827 CSEDVTRP-GVIVSPGFGtedhygnyDGYDNNLNCIYNI-TNPNSTecITVSFISFDLGQPSENCSDYVQITDTEGGVDF 1904
Cdd:pfam00431 1 CGGVLTDSsGSISSPNYP--------NPYPPNKDCVWLIrAPPGFR--VKLTFQDFELEDHDECGYDYVEIRDGPSASSP 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 47551295 1905 L---YCG--LPenttaPVFYSRSANVEVVFRTGEDERNDGF 1940
Cdd:pfam00431 71 LlgrFCGsgIP-----EDIVSSSNQMTIKFVSDASVQKRGF 106
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
1662-1758 |
5.77e-05 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 44.69 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 1662 ITFPMSNDYYLYNDECTLTITNENGCM-MLFFTSLDIDEGlgDTCYNDYLMIFDPINVYANE--PYCGNAINTMPYKTIG 1738
Cdd:smart00042 3 ITSPNYPQSYPNNLDCVWTIRAPPGYRiELQFTDFDLESS--DNCEYDYVEIYDGPSASSPLlgRFCGSEAPPPVISSSS 80
|
90 100
....*....|....*....|
gi 47551295 1739 NTVELTLRTEDAERFKSFEV 1758
Cdd:smart00042 81 NSLTLTFVSDSSVQKRGFSA 100
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
760-810 |
5.99e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.96 E-value: 5.99e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 760 TSFGDCSVSCGPGLRSRSIFCVSESNQvVDDSFCAGLvrQVESESCNLTPC 810
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPCTGE--DVETRACNEQPC 52
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
3329-3611 |
6.47e-05 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 48.13 E-value: 6.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3329 GNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFP 3408
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGGGGG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3409 IGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDF 3488
Cdd:COG3291 130 TGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGTAG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3489 PIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDF 3568
Cdd:COG3291 210 VTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGGLG 289
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 47551295 3569 TIGNNTVTYSASDDAGNTEYCTFFVVVSDCNYTIDGASMVSGN 3611
Cdd:COG3291 290 TTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTV 332
|
|
| CUB |
cd00041 |
CUB domain; extracellular domain; present in proteins mostly known to be involved in ... |
3598-3700 |
7.74e-05 |
|
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Pssm-ID: 238001 [Multi-domain] Cd Length: 113 Bit Score: 44.71 E-value: 7.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3598 CNYTIDGASmvSGNLSSPNYPNSSPSGLSCPITFIIPQGTVLNIMIVEFNL--DASCS-EYIKL----TANVAGETNFCS 3670
Cdd:cd00041 1 CGGTLTAST--SGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLesSPNCSyDYLEIydgpSTSSPLLGRFCG 78
|
90 100 110
....*....|....*....|....*....|
gi 47551295 3671 NdiTLPASATYTSDTMVsFLYVTDNDDSNT 3700
Cdd:cd00041 79 S--TLPPPIISSGNSLT-VRFRSDSSVTGR 105
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1773-1825 |
8.53e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.57 E-value: 8.53e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1773 GPWSECSLSCDGGVRTRDVFCMNlaTRQTDREALCEGSPFyEpMEECNTEECP 1825
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGEDV-E-TRACNEQPCP 53
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1957-2008 |
1.24e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.19 E-value: 1.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 1957 GNFSECSVTCGEGVEYRRVGCTrlSDSQLVTDDFCNDQRPsDSRPCSLPECP 2008
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCC--SPPPQNGGGPCTGEDV-ETRACNEQPCP 53
|
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
3086-3583 |
1.29e-04 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 48.02 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3086 GNNTVTYSASDDAGNTETCT---FFVIVSDNENPV-ISGCPSDQNVATDIGNATAVVIWTPPT--------ATDNSGNQT 3153
Cdd:COG4733 500 EDGTYTITAVQHAPEKYAAIdagAFDDVPPQWPPVnVTTSESLSVVAQGTAVTTLTVSWDAPAgavayeveWRRDDGNWV 579
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3154 ----LTSTNNPGDDFPIGNNTVT---YSASDDAGNTETCTFFVVVSDNENPvisgcPSDQNVTTDIGNATAVVIWTPPTA 3226
Cdd:COG4733 580 svprTSGTSFEVPGIYAGDYEVRvraINALGVSSAWAASSETTVTGKTAPP-----PAPTGLTATGGLGGITLSWSFPVD 654
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3227 TDNSGSQTLTSTNNPGDD--FPIGNNTVTYSASDDAGNTETCTFFVVVSDNeipvfSGCPSDQNVTtdiGNATAVVIWTP 3304
Cdd:COG4733 655 ADTLRTEIRYSTTGDWASatVAQALYPGNTYTLAGLKAGQTYYYRARAVDR-----SGNVSAWWVS---GQASADAAGIL 726
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3305 PTATDnsgsQTLTSTNNPGDDFPIGNNTVTY--SASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVI 3382
Cdd:COG4733 727 DAITG----QILETELGQELDAIIQNATVAEvvAATVTDVTAQIDTAVLFAGVATAAAIGAEARVAATVAESATAAAATG 802
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3383 WTPPTATDNSGNQTLTSTNNPGddfpignntvtysASDDAGNTetcTFFVVVSDNEIPVISGCPSDQNVATDIGNATAVV 3462
Cdd:COG4733 803 TAADAAGDASGGVTAGTSGTTG-------------AGDTAAST---TRVAAAVVLAGVVVYGDAIIESGNTGDIVATGDI 866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3463 TwtppTATDNSVNQTLTSTNNPGDDFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCpsDQNVAISIGNAAVV 3542
Cdd:COG4733 867 A----SAAAGAVATTVSGTTAADVSAVADSTAASLTAIVIAATTIIDAIGDGTTREPAGDIGAS--GGAQGFAVTIVGSF 940
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 47551295 3543 TWTPPTATDNSGNQTltsTNNPGDDFTIGNNTVTYSASDDA 3583
Cdd:COG4733 941 DGAGAVATVDAGQSV---VDGVGTAVEAANGTETAAGGGSQ 978
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2132-2182 |
1.35e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 42.19 E-value: 1.35e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 2132 GEYGECDVSCGSGVQTREVECTDltTQESVAMGLCTDPmPPSTTECNEEPC 2182
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGE-DVETRACNEQPC 52
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
1119-1171 |
2.34e-04 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 41.25 E-value: 2.34e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 47551295 1119 TPWSACSVTCALGVQTRGVSCVTRKGSGVvidemDCSNMTRpsESRECYLDPC 1171
Cdd:pfam00090 4 SPWSPCSVTCGKGIQVRQRTCKSPFPGGE-----PCTGDDI--ETQACKMDKC 49
|
|
| PRK12688 |
PRK12688 |
flagellin; Reviewed |
2794-3242 |
3.27e-04 |
|
flagellin; Reviewed
Pssm-ID: 171664 [Multi-domain] Cd Length: 751 Bit Score: 46.80 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2794 ISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPI-GNNTVTYSASDDAGNTETCTFFVVVSDNEI 2872
Cdd:PRK12688 102 VVGYSTKSNVSTTISGATADDLRGTTSYASATASSNVLYDGAAGGATAAtGATTLGGTAGSLAGTGATAGDGTTALTGTI 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2873 PVFSGCPSdqNVTTDIGNAtavviwtPPTATD----NSGNQTLTSTNNPGDD-FPIGNNTVTYSANDDAGNTETCTFFVV 2947
Cdd:PRK12688 182 TLIATNGT--TATGLLGNA-------QPADGDtltvNGKTITFRSGAAPASTaVPSGSGVSGNLVTDGNGNSTVYLGSAT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2948 VSD--NEIPVISGCPSdqnvATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPI------------------GNN 3007
Cdd:PRK12688 253 VNDllSAIDLASGVQT----VTISSGAATIAVSASGGAVSAAAAGAVTLKSSTGADLSVtgkadllkalglttatgaGNA 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3008 TVTYSANDDAG--------------NTETCTFfvvvSDNEIP----VFSGCPSDQNVTTDiGNATAVVIWTPPTATD--- 3066
Cdd:PRK12688 329 TVNANRTTSAGslgaliqdgstlnvDGKTITF----KNAPIPgaasVPSGYGASGNVLTD-GNGNSTVYLQGGTINDvlk 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3067 ----NSGSQTLTSTNnpgddfpiGNNTVTYSASDDAGNtetctffvIVSDNENPVISGCPSDQNVaTDIGNATAVVIWTP 3142
Cdd:PRK12688 404 aidlATGVQTATIAN--------GTATLATAAGQTASS--------VNASGQLKLSTGLNADLSI-TGTGNALSALGLAG 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3143 PTATDNSGNQTLTSTNNpgddfPIGNNTVTYSASDDaGNTETCTFfvvvSDNENPVISGCpSDQNVTTDIGNATAVVIWT 3222
Cdd:PRK12688 467 NTGTATAFTAARTAGAG-----GISGKTLTFTSFNG-GTAVNVTF----GDGTNGTVKTL-AQLNTALQANNLTATIDAT 535
|
490 500
....*....|....*....|...
gi 47551295 3223 PP---TATDNSGSQTLTSTNNPG 3242
Cdd:PRK12688 536 GKltiSASNDYASSTLGSTLAGG 558
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2304-2355 |
3.45e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 41.03 E-value: 3.45e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 47551295 2304 SNFSECSVSCGEGFRTRDVLCTRleTGENVSRDNCDENEilPNIEPCNEQPC 2355
Cdd:smart00209 5 SEWSPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGED--VETRACNEQPC 52
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
3248-3533 |
5.00e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 45.43 E-value: 5.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3248 GNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVviWTPPTATDNSGSQTLTSTNNPGDDFP 3327
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGA--TTVVAGSTVGTGVATSTTTAAAPGGG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3328 IGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDF 3407
Cdd:COG3291 128 GGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3408 PIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDD 3487
Cdd:COG3291 208 AGVTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGG 287
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 47551295 3488 FPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVA 3533
Cdd:COG3291 288 LGTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTVF 333
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
2843-3128 |
5.51e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 45.43 E-value: 5.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2843 GNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDfp 2922
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGGG-- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2923 IGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDF 3002
Cdd:COG3291 128 GGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3003 PIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDD 3082
Cdd:COG3291 208 AGVTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGG 287
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 47551295 3083 FPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVA 3128
Cdd:COG3291 288 LGTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTVF 333
|
|
| CUB |
smart00042 |
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ... |
3610-3700 |
7.54e-04 |
|
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.
Pssm-ID: 214483 [Multi-domain] Cd Length: 102 Bit Score: 41.61 E-value: 7.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3610 GNLSSPNYPNSSPSGLSCPITFIIPQGTVLNIMIVEFNLDASCS---EYIKLT--ANVAGET--NFCSNdiTLPASATYT 3682
Cdd:smart00042 1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDNceyDYVEIYdgPSASSPLlgRFCGS--EAPPPVISS 78
|
90
....*....|....*...
gi 47551295 3683 SDTMVSFLYVTDNDDSNT 3700
Cdd:smart00042 79 SSNSLTLTFVSDSSVQKR 96
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
2762-3047 |
7.81e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.66 E-value: 7.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2762 GNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPSDQNVTTDIGNATAVviWTPPTATDNSGSQTLTSTNNPGDDFP 2841
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGA--TTVVAGSTVGTGVATSTTTAAAPGGG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2842 IGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDF 2921
Cdd:COG3291 128 GGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2922 PIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDD 3001
Cdd:COG3291 208 AGVTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGG 287
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 47551295 3002 FPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVT 3047
Cdd:COG3291 288 LGTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTVF 333
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
3167-3452 |
8.37e-04 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.66 E-value: 8.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3167 GNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVviWTPPTATDNSGSQTLTSTNNPGDDFP 3246
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGA--TTVVAGSTVGTGVATSTTTAAAPGGG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3247 IGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDF 3326
Cdd:COG3291 128 GGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3327 PIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDD 3406
Cdd:COG3291 208 AGVTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGG 287
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 47551295 3407 FPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVA 3452
Cdd:COG3291 288 LGTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTVF 333
|
|
| CUB |
pfam00431 |
CUB domain; |
2361-2463 |
8.78e-04 |
|
CUB domain;
Pssm-ID: 395345 [Multi-domain] Cd Length: 110 Bit Score: 41.51 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2361 FFGDSALFESPGFPSEYPENLQCVydfynindecWRITAYY----------FDLQDkeNDQCRDRFFVEDVGFAGREPYI 2430
Cdd:pfam00431 5 LTDSSGSISSPNYPNPYPPNKDCV----------WLIRAPPgfrvkltfqdFELED--HDECGYDYVEIRDGPSASSPLL 72
|
90 100 110
....*....|....*....|....*....|....*.
gi 47551295 2431 A--CGQEFS-PVLSFSRTIRITFFSDDKYSGRGFSA 2463
Cdd:pfam00431 73 GrfCGSGIPeDIVSSSNQMTIKFVSDASVQKRGFKA 108
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
2924-3209 |
1.11e-03 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.28 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2924 GNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDfp 3003
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGGG-- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3004 IGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDF 3083
Cdd:COG3291 128 GGTGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3084 PIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDD 3163
Cdd:COG3291 208 AGVTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGG 287
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 47551295 3164 FPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVT 3209
Cdd:COG3291 288 LGTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGSSSTGTVF 333
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
3005-3265 |
1.18e-03 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 44.28 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3005 GNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATA--VVIWTPPTATDNSGSQTLTSTNNPGDD 3082
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGatTVVAGSTVGTGVATSTTTAAAPGGGGG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3083 FPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGD 3162
Cdd:COG3291 130 TGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGTAG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3163 DFPIGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPG 3242
Cdd:COG3291 210 VTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTPGTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGGLG 289
|
250 260
....*....|....*....|...
gi 47551295 3243 DDFPIGNNTVTYSASDDAGNTET 3265
Cdd:COG3291 290 TTTAITPGNVSTTADVTGGTATL 312
|
|
| COG3291 |
COG3291 |
Uncharacterized conserved protein, PKD repeat domain [Function unknown]; |
3086-3363 |
1.55e-03 |
|
Uncharacterized conserved protein, PKD repeat domain [Function unknown];
Pssm-ID: 442520 [Multi-domain] Cd Length: 333 Bit Score: 43.89 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3086 GNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFP 3165
Cdd:COG3291 50 GTYTVTLTVTDAAGCSDTTTKTITVGAPNPGVTTVTTSTTVTTLANTANGGATTVVAGSTVGTGVATSTTTAAAPGGGGG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3166 IGNNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDF 3245
Cdd:COG3291 130 TGTTTTTGTDTGLTGSTGTASDTATVTTSVSTTDVTSDGTTSASTNPSVTTDTVTTLTGSYTGTIVGGSGSGTVTSGTAG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3246 PIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGcPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDD 3325
Cdd:COG3291 210 VTTGATSGTSGTGSATSGVAVTDVTLTGISTGDAGTP-GTNTVTTSGANTAGTSTITGGTSGVVTTSAATGTSTNGTGGL 288
|
250 260 270
....*....|....*....|....*....|....*...
gi 47551295 3326 FPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISG 3363
Cdd:COG3291 289 GTTTAITPGNVSTTADVTGGTATLAVSSTLTTNDTTGS 326
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
635-688 |
1.58e-03 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 39.36 E-value: 1.58e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 635 FYDNYGECSVTCDTGVQSRTAFCATSDGTSESV-EICRLLfSSVVTERTCNPVPC 688
Cdd:pfam19030 2 VAGPWGECSVTCGGGVQTRLVQCVQKGGGSIVPdSECSAQ-KKPPETQSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1599-1649 |
1.85e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 39.11 E-value: 1.85e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 1599 PFGNCSEICGVGNRTRELECVNAltNELTGRDECPdEEPPTTEPCFIEECP 1649
Cdd:smart00209 6 EWSPCSVTCGGGVQTRTRSCCSP--PPQNGGGPCT-GEDVETRACNEQPCP 53
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
1773-1824 |
2.70e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 38.41 E-value: 2.70e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 1773 GPWSECSLSCDGGVRTRdvfcmnlaTRQTDREALCEGSPFYEPMEE--CNTEEC 1824
Cdd:pfam19028 7 SEWSECSVTCGGGVQTR--------TRTVIVEPQNGGRPCPELLERrpCNLPPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
2478-2530 |
2.92e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 38.34 E-value: 2.92e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 47551295 2478 GPYSE--ECSATCGEGVVYRNVTCQDlmTRAVVNDSLCSELRPsEIKPCRREPCP 2530
Cdd:smart00209 2 SEWSEwsPCSVTCGGGVQTRTRSCCS--PPPQNGGGPCTGEDV-ETRACNEQPCP 53
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
3251-3569 |
3.57e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 42.84 E-value: 3.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3251 TVTYSASDDAGNTetctffvvvsdNEIPVFSGCPSDQNVTTDIGNATAVVIWTpptaTDNSGSQTLTSTNNPGDDFPIGN 3330
Cdd:COG3979 65 TFTVGACDAAGNV-----------SAASGTSTAMFGGSSTTLGSAEGVADTSG----NLAASGAFFGVTTPPTPSSTLVV 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3331 NTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIG 3410
Cdd:COG3979 130 DGTTTVNAAATANGGTGGSGGTTTIITTGVEGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3411 NNTVTYSASDDAGNTETCTFFVVVSDNEIPVISGCpSDQNVATDIGNATAVVTWTPPTATDNSVNQTLTSTNNPGDDFPI 3490
Cdd:COG3979 210 GNTYWALNTLGVSDTPSGTTATGGTVGITSAYGAG-VSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDA 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 47551295 3491 GNNTVTYSASDDAGNTeTCTFFVVVSDNENPVISGCPSDQNVAISIGNAAVVTWTPPTATDNSGNQTLTSTNNPGDDFT 3569
Cdd:COG3979 289 AVTGLNDGAANGPTGG-YGATGTTVAGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
2846-3144 |
4.06e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 42.84 E-value: 4.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2846 TVTYSASDDAGNTETCTFFVVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDD----F 2921
Cdd:COG3979 65 TFTVGACDAAGNVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAAtangG 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2922 PIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDD 3001
Cdd:COG3979 145 TGGSGGTTTIITTGVEGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYWALNTLGVSDT 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3002 FPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVFSGCPSDQN-VTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPG 3080
Cdd:COG3979 225 PSGTTATGGTVGITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNtGTTSGTATSDAATNDVGDAAVTGLNDGAANGPTGG 304
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 47551295 3081 DDFPIGNNTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPT 3144
Cdd:COG3979 305 YGATGTTVAGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTTAP 368
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
581-628 |
4.77e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 37.95 E-value: 4.77e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 47551295 581 GQCSVTCGTGSETRVVNCVDSESNiVDDSLCTDERpPEVIECASTPCP 628
Cdd:smart00209 8 SPCSVTCGGGVQTRTRSCCSPPPQ-NGGGPCTGED-VETRACNEQPCP 53
|
|
| flgK |
PRK06945 |
flagellar hook-associated protein FlgK; Validated |
3389-3585 |
4.82e-03 |
|
flagellar hook-associated protein FlgK; Validated
Pssm-ID: 235895 [Multi-domain] Cd Length: 651 Bit Score: 42.70 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3389 TDNSGNQTLTST-NNPGD----DFPIGNNTVTYSASDDAGNTETCTFFVVVSDNEIPV------ISGCPS--DQ------ 3449
Cdd:PRK06945 338 ANNTGSATLTASiTNASAlttsDYTLSYDGTNYTLTRLSDGSVVGTATSLPTPPPTTIdglslsLSGTMNagDSflvqpt 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3450 -NVATDIGNAT----AVVTWTP---PTATDNSVNQTLTS-TNNPGDDFPIGNNTVTYSAsddAGNTetctffvvvsdnen 3520
Cdd:PRK06945 418 rNAANGFSVATtdgsAIAAASPvraSAGSTNTGTGAISQgSVSSGYPLPSGTTTLTYDA---ATGT-------------- 480
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 3521 pvISGCPSDQNVAISIGNAAVVTWTPPTA------------TDNSGNQTLTSTNNPGDDFTIGNNTvtySASDDAGN 3585
Cdd:PRK06945 481 --LSGFPAGTTVTVAGTPPTSVTITPATTpvpytsgagislVFNGVSVTLSGTPADGDTFTIGPNT---GGTNDGRN 552
|
|
| TSP1_CCN |
pfam19035 |
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ... |
1118-1171 |
5.16e-03 |
|
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.
Pssm-ID: 465952 Cd Length: 44 Bit Score: 37.31 E-value: 5.16e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 47551295 1118 ATPWSACSVTCALGVQTRgvscvtrkgsgVVIDEMDCSNMTrpsESRECYLDPC 1171
Cdd:pfam19035 5 STEWSPCSKTCGMGVSTR-----------VSNDNAECKLVT---ETRLCQLRPC 44
|
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
2723-3118 |
6.92e-03 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 42.62 E-value: 6.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2723 VTTDIGNATAVVYWTPPTPPPDYSVN-------------KTSTNNPGDDFPIGNNTVT---YSASDDEGNTETCTFFVVV 2786
Cdd:COG4733 545 VAQGTAVTTLTVSWDAPAGAVAYEVEwrrddgnwvsvprTSGTSFEVPGIYAGDYEVRvraINALGVSSAWAASSETTVT 624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2787 SDNEIPvisgcPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDD--FPIGNNTVTYSASDDAGNTETCTFF 2864
Cdd:COG4733 625 GKTAPP-----PAPTGLTATGGLGGITLSWSFPVDADTLRTEIRYSTTGDWASatVAQALYPGNTYTLAGLKAGQTYYYR 699
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2865 VVVSDNeipvfSGCPSDQNVTtdiGNATAVVIWTPPTATDnsgnQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTF 2944
Cdd:COG4733 700 ARAVDR-----SGNVSAWWVS---GQASADAAGILDAITG----QILETELGQELDAIIQNATVAEVVAATVTDVTAQID 767
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2945 FVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCT 3024
Cdd:COG4733 768 TAVLFAGVATAAAIGAEARVAATVAESATAAAATGTAADAAGDASGGVTAGTSGTTGAGDTAASTTRVAAAVVLAGVVVY 847
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3025 FFVVVSDNEIPVFSGC----------PSDQNVTTDIGNATAVVIWT-------PPTATDNSGSQTLTSTNNPGDDFPIGN 3087
Cdd:COG4733 848 GDAIIESGNTGDIVATgdiasaaagaVATTVSGTTAADVSAVADSTaasltaiVIAATTIIDAIGDGTTREPAGDIGASG 927
|
410 420 430
....*....|....*....|....*....|....*.
gi 47551295 3088 NTVTY-----SASDDAGNTETCTFFVIVSDNENPVI 3118
Cdd:COG4733 928 GAQGFavtivGSFDGAGAVATVDAGQSVVDGVGTAV 963
|
|
| ZnMc_MMP_like_1 |
cd04279 |
Zinc-dependent metalloprotease; MMP_like sub-family 1. A group of bacterial, archaeal, and ... |
293-384 |
7.19e-03 |
|
Zinc-dependent metalloprotease; MMP_like sub-family 1. A group of bacterial, archaeal, and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin.
Pssm-ID: 239806 [Multi-domain] Cd Length: 156 Bit Score: 40.13 E-value: 7.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 293 EWQKDEKSDISILLtRRDLEIGGND---AVTGKSKDIGGACDPSRRCIIAQDHGPSG---TIFTLA-HEIGHSLGIYHdd 365
Cdd:cd04279 44 NPEEDNDADIVIFF-DRPPPVGGAGgglARAGFPLISDGNRKLFNRTDINLGPGQPRgaeNLQAIAlHELGHALGLWH-- 120
|
90
....*....|....*....
gi 47551295 366 sESgcANNKNIMATDNSGG 384
Cdd:cd04279 121 -HS--DRPEDAMYPSQGQG 136
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
3008-3334 |
8.33e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 41.68 E-value: 8.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3008 TVTYSANDDAGNTetctffvvvsdNEIPVFSGCPSDQNVTTDIGNATAVVIWTpptaTDNSGSQTLTSTNNPGDDFPIGN 3087
Cdd:COG3979 65 TFTVGACDAAGNV-----------SAASGTSTAMFGGSSTTLGSAEGVADTSG----NLAASGAFFGVTTPPTPSSTLVV 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3088 NTVTYSASDDAGNTETCTFFVIVSDNENPVISGCPSDQNVATDIGNATAVVIWTPPTATDNSGNQTLTSTNNPGDDFPIG 3167
Cdd:COG3979 130 DGTTTVNAAATANGGTGGSGGTTTIITTGVEGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3168 NNTVTYSASDDAGNTETCTFFVVVSDNENPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFPI 3247
Cdd:COG3979 210 GNTYWALNTLGVSDTPSGTTATGGTVGITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAA 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 3248 GNNTVTYSASDDAGNTETCTFFVVVSDNEIPVFSGcpsdqnvTTDIGNATAVVIWTPPTATDNSGSQTLTSTNNPGDDFP 3327
Cdd:COG3979 290 VTGLNDGAANGPTGGYGATGTTVAGAAGVGGTKSG-------TGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGA 362
|
....*..
gi 47551295 3328 IGNNTVT 3334
Cdd:COG3979 363 GSTTAPD 369
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
1119-1171 |
8.62e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 36.87 E-value: 8.62e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 47551295 1119 TPWSACSVTCALGVQTRgvscvTRKgsgVVIDEMD----CsnmTRPSESRECYLDPC 1171
Cdd:pfam19028 7 SEWSECSVTCGGGVQTR-----TRT---VIVEPQNggrpC---PELLERRPCNLPPC 52
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
1062-1112 |
9.24e-03 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 36.80 E-value: 9.24e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 47551295 1062 GDCSVTCGDGVRVRNVLCYAIAGgnfePVVGSLCNPllEPPSEEICDLEDC 1112
Cdd:smart00209 8 SPCSVTCGGGVQTRTRSCCSPPP----QNGGGPCTG--EDVETRACNEQPC 52
|
|
| Hia |
COG5295 |
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ... |
2750-3017 |
9.62e-03 |
|
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain] Cd Length: 785 Bit Score: 42.06 E-value: 9.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2750 TSTNNPGDDFPIGNNTVTYSASDDEGNTETCTFFVVVSDNEIPVISGCPSDQNVTTDIGNATAVVIWTPPTATDNSGSQT 2829
Cdd:COG5295 387 AAGAAGAGSAGSGGSSTGASAGGGASAAGGAAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAGGGTAGAGGAANVG 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2830 LTSTNNpgddfpIGNNTVTYSASDDAGNTETCTffvVVSDNEIPVFSGCPSDQNVTTDIGNATAVVIWTPPTATDNSGNQ 2909
Cdd:COG5295 467 AATTAA------SAAATAAAATSSAAIAGATAT---GAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGG 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47551295 2910 TLTSTNNPGDDFPIGNNTVTYSANDDAGNTETCTFFVVVSDNEIPVISGCPSDQNVATDSGNATAVVIWTPPTATDNSGN 2989
Cdd:COG5295 538 AAAAAGGGSTTAATGTNSVAVGNNTATGANSVALGAGSVASGANSVSVGAAGAENVAAGATDTDAVNGGGAVATGDNSVA 617
|
250 260
....*....|....*....|....*...
gi 47551295 2990 QTLTSTNNPGDDFPIGNNTVTYSANDDA 3017
Cdd:COG5295 618 VGNNAQASGANSVALGAGATATANNSVA 645
|
|
| |
