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Conserved domains on  [gi|499168592|ref|WP_010866868|]
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MULTISPECIES: (2Fe-2S)-binding protein [Aeropyrum]

Protein Classification

(2Fe-2S)-binding protein( domain architecture ID 11449880)

(2Fe-2S)-binding protein is the small subunit of a dehydrogenase or oxidoreductase enzyme complex such as carbon monoxide dehydrogenase and isoquinoline 1-oxidoreductase; contains a a 2Fe-2S ferredoxin-type domain which binds 2Fe-2S clusters

Gene Ontology:  GO:0046872|GO:0051536|GO:0051537
SCOP:  3000113

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 9-162 5.72e-95

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.58  E-value: 5.72e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:COG2080    2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499168592  89 GKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMRG 162
Cdd:COG2080   82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALRG 155
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 9-162 5.72e-95

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.58  E-value: 5.72e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:COG2080    2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499168592  89 GKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMRG 162
Cdd:COG2080   82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALRG 155
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
9-161 5.96e-91

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 261.65  E-value: 5.96e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:NF041020   9 VKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSKD 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499168592  89 GKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMR 161
Cdd:NF041020  89 GKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQKMK 161
4hydroxCoAred TIGR03193
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ...
 11-157 6.87e-56

4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.


Pssm-ID: 132237 [Multi-domain]  Cd Length: 148  Bit Score: 172.37  E-value: 6.87e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   11 VTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQNGK 90
Cdd:TIGR03193   2 LRLTVNGRWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRLACSTLAHRVAGRKVETVEGLATNGR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499168592   91 LHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAA 157
Cdd:TIGR03193  82 LSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAAA 148
PRK09908 PRK09908
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
7-154 3.25e-46

xanthine dehydrogenase iron sulfur-binding subunit XdhC;


Pssm-ID: 182139 [Multi-domain]  Cd Length: 159  Bit Score: 148.14  E-value: 3.25e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   7 PLVRVTLKVNGKTYTHHVPPRMLLVHFLRDvLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLE 86
Cdd:PRK09908   5 ETITIECTINGMPFQLHAAPGTPLSELLRE-QGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEA 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  87 QNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLS--RNKSPTESEVRRAIEGNLCRCTGYVNIVRSAL 154
Cdd:PRK09908  84 KGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAkpREKPLTITEIRRGLAGNLCRCTGYQMIVNTVL 153
Fer2_2 pfam01799
[2Fe-2S] binding domain;
81-153 2.97e-39

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 127.55  E-value: 2.97e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499168592   81 TIEGLEQNGKlHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKS-PTESEVRRAIEGNLCRCTGYVNIVRSA 153
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPpPTEAEIREALSGNLCRCTGYRRIVDAV 73
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 11-60 2.22e-04

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 38.14  E-value: 2.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 499168592  11 VTLKVNGKTYTHHVPPRMLLVHFLRDvLGLTgTHVGCDTSNCGACTVLVN 60
Cdd:cd00207    1 VTINVPGSGVEVEVPEGETLLDAARE-AGID-IPYSCRAGACGTCKVEVV 48
 
Name Accession Description Interval E-value
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 9-162 5.72e-95

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 271.58  E-value: 5.72e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:COG2080    2 MMITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAED 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499168592  89 GKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMRG 162
Cdd:COG2080   82 GELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVRAVKRAAAALRG 155
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
9-161 5.96e-91

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 261.65  E-value: 5.96e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:NF041020   9 VKIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSKD 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499168592  89 GKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMR 161
Cdd:NF041020  89 GKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVKEASQKMK 161
4hydroxCoAred TIGR03193
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ...
 11-157 6.87e-56

4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.


Pssm-ID: 132237 [Multi-domain]  Cd Length: 148  Bit Score: 172.37  E-value: 6.87e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   11 VTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQNGK 90
Cdd:TIGR03193   2 LRLTVNGRWREDAVADNMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDGRPRLACSTLAHRVAGRKVETVEGLATNGR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499168592   91 LHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAA 157
Cdd:TIGR03193  82 LSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEAAA 148
XdhA COG4630
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ...
 9-160 1.38e-50

Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];


Pssm-ID: 443668 [Multi-domain]  Cd Length: 476  Bit Score: 168.01  E-value: 1.38e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   9 VRVTLkvNGKTYT-HHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLV----NGK----AVKSCTVYTFMVDGAEI 79
Cdd:COG4630    1 IRFLL--NGELVElSDVPPTTTLLDWLREDRGLTGTKEGCAEGDCGACTVVVgeldDGGlryrAVNACILFLPQLDGKAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  80 TTIEGL-EQNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRsalwAAE 158
Cdd:COG4630   79 VTVEGLaGPDGALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIID----AAR 154


                 ..
gi 499168592 159 RM 160
Cdd:COG4630  155 AM 156
PRK09908 PRK09908
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
7-154 3.25e-46

xanthine dehydrogenase iron sulfur-binding subunit XdhC;


Pssm-ID: 182139 [Multi-domain]  Cd Length: 159  Bit Score: 148.14  E-value: 3.25e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   7 PLVRVTLKVNGKTYTHHVPPRMLLVHFLRDvLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLE 86
Cdd:PRK09908   5 ETITIECTINGMPFQLHAAPGTPLSELLRE-QGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEA 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  87 QNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLS--RNKSPTESEVRRAIEGNLCRCTGYVNIVRSAL 154
Cdd:PRK09908  84 KGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAkpREKPLTITEIRRGLAGNLCRCTGYQMIVNTVL 153
xanthine_xdhA TIGR02963
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ...
 15-160 4.84e-46

xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 274365 [Multi-domain]  Cd Length: 467  Bit Score: 156.28  E-value: 4.84e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   15 VNGKTYT-HHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLV---------NGKAVKSCTVYTFMVDGAEITTIEG 84
Cdd:TIGR02963   5 LNGETVTlSDVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVgelvdggklRYRSVNACIQFLPSLDGKAVVTVED 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499168592   85 L-EQNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRsalwAAERM 160
Cdd:TIGR02963  85 LrQPDGRLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILD----AAEAA 157
pucE TIGR03198
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ...
 9-153 3.14e-45

xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.


Pssm-ID: 132242 [Multi-domain]  Cd Length: 151  Bit Score: 145.38  E-value: 3.14e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592    9 VRVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQN 88
Cdd:TIGR03198   2 EQFRFTVNGQAWEVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGKLANACLTMAYQADGHEITTIEGIAEN 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499168592   89 GkLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSA 153
Cdd:TIGR03198  82 E-LDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSA 145
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 10-159 1.82e-42

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 140.68  E-value: 1.82e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  10 RVTLKVNGKTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQNG 89
Cdd:PRK11433  51 PVTLKVNGKTEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPD 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  90 KLHPIQEAFWENHGLQCGFCTPGMIMT---------------LHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSAL 154
Cdd:PRK11433 131 NLHPMQAAFVKHDGFQCGYCTPGQICSsvavlkeikdgipshVTVDLTAAPELTADEIRERMSGNICRCGAYSNILEAIE 210


                 ....*
gi 499168592 155 WAAER 159
Cdd:PRK11433 211 DVAGE 215
Se_dep_XDH TIGR03311
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ...
 11-163 2.81e-42

selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 132354 [Multi-domain]  Cd Length: 848  Bit Score: 149.61  E-value: 2.81e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   11 VTLKVNGKTYThhVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQNGK 90
Cdd:TIGR03311   1 YEFIVNGREVD--VNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGKAVRACRFTTAKLAGKEITTVEGLTEREK 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499168592   91 lHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIVRSALWAAERMRGG 163
Cdd:TIGR03311  79 -DVYAWAFAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVRLAAKAFREE 150
Fer2_2 pfam01799
[2Fe-2S] binding domain;
81-153 2.97e-39

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 127.55  E-value: 2.97e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499168592   81 TIEGLEQNGKlHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKS-PTESEVRRAIEGNLCRCTGYVNIVRSA 153
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLERNPPpPTEAEIREALSGNLCRCTGYRRIVDAV 73
PLN02906 PLN02906
xanthine dehydrogenase
 28-150 3.28e-39

xanthine dehydrogenase


Pssm-ID: 215491 [Multi-domain]  Cd Length: 1319  Bit Score: 140.99  E-value: 3.28e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   28 MLLVHFLRDvLGLTGTHVGCDTSNCGACTVLVNGK----------AVKSCTVYTFMVDGAEITTIEGL-EQNGKLHPIQE 96
Cdd:PLN02906    2 QTLLEYLRD-LGLTGTKLGCGEGGCGACTVMVSHYdrktgkcvhyAVNACLAPLYSVEGMHVITVEGIgNRRDGLHPVQE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 499168592   97 AFWENHGLQCGFCTPGMIMTLHDFLSRNK-SPTESEVRRAIEGNLCRCTGYVNIV 150
Cdd:PLN02906   81 ALASMHGSQCGFCTPGFIMSMYALLRSSKtPPTEEQIEECLAGNLCRCTGYRPIL 135
mam_aldehyde_ox TIGR02969
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
 15-150 2.23e-35

aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.


Pssm-ID: 132014 [Multi-domain]  Cd Length: 1330  Bit Score: 129.74  E-value: 2.23e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592    15 VNG-KTYTHHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVL---------------VNGKAVKSCTVYtfmvdGAE 78
Cdd:TIGR02969    7 VNGrKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMisrynpstksirhhpVNACLTPICSLY-----GAA 81

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499168592    79 ITTIEGL-EQNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEVRRAIEGNLCRCTGYVNIV 150
Cdd:TIGR02969   82 VTTVEGIgSTRTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPII 154
PLN00192 PLN00192
aldehyde oxidase
 3-150 1.14e-30

aldehyde oxidase


Pssm-ID: 215096 [Multi-domain]  Cd Length: 1344  Bit Score: 116.35  E-value: 1.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592    3 KAATPLVrvtLKVNGKTY-THHVPPRMLLVHFLRDVLGLTGTHVGCDTSNCGACTVL----------VNGKAVKSCTVYT 71
Cdd:PLN00192    1 SSNMSLV---FAVNGERFeLSSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLlskydpvldqVEDFTVSSCLTLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592   72 FMVDGAEITTIEGLeQNGK--LHPIQEAFWENHGLQCGFCTPGMIMTLH------DFLSRNKSP------TESEVRRAIE 137
Cdd:PLN00192   78 CSVNGCSITTSEGL-GNSKdgFHPIHKRFAGFHASQCGFCTPGMCISLFsalvnaDKTDRPEPPsgfsklTVVEAEKAVS 156

                         170
                  ....*....|...
gi 499168592  138 GNLCRCTGYVNIV 150
Cdd:PLN00192  157 GNLCRCTGYRPIV 169
PRK09800 PRK09800
putative hypoxanthine oxidase; Provisional
 53-161 1.25e-11

putative hypoxanthine oxidase; Provisional


Pssm-ID: 182084 [Multi-domain]  Cd Length: 956  Bit Score: 61.77  E-value: 1.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499168592  53 GACTVLVNGKAVKSCTVYTFMVDGAEITTIEGLEQNGKLHPIQEAFWENHGLQCGFCTPGMIMTLHDFLSRNKSPTESEV 132
Cdd:PRK09800  45 GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEI 124

                         90       100
                 ....*....|....*....|....*....
gi 499168592 133 RRAIEGNLCRCTGYVNIVRSALWAAERMR 161
Cdd:PRK09800 125 DDALSGLFSRDAGWQQYYQVIELAVARKN 153
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 11-60 2.22e-04

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 38.14  E-value: 2.22e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 499168592  11 VTLKVNGKTYTHHVPPRMLLVHFLRDvLGLTgTHVGCDTSNCGACTVLVN 60
Cdd:cd00207    1 VTINVPGSGVEVEVPEGETLLDAARE-AGID-IPYSCRAGACGTCKVEVV 48
PRK08493 PRK08493
NADH-quinone oxidoreductase subunit G;
46-109 6.76e-04

NADH-quinone oxidoreductase subunit G;


Pssm-ID: 236277 [Multi-domain]  Cd Length: 819  Bit Score: 38.92  E-value: 6.76e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499168592  46 GCD-TSNCGACTVLVNGKAVKSCTvyTFMVDGAEITT-IEGLEQNGKlhPIQEAFWENHGLQCGFC 109
Cdd:PRK08493  38 GCSpTLACRLCMVEADGKRVYSCN--TKAKEGMNILTnTPNLMDERN--AIMQTYDVNHPLECGVC 99
sdhB PRK08640
succinate dehydrogenase iron-sulfur subunit; Reviewed
 52-93 7.88e-03

succinate dehydrogenase iron-sulfur subunit; Reviewed


Pssm-ID: 181515 [Multi-domain]  Cd Length: 249  Bit Score: 35.35  E-value: 7.88e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 499168592  52 CGACTVLVNGKAVKSCTvytfmvdgaeiTTIEGLEQNGKLHP 93
Cdd:PRK08640  68 CGACSMVINGKPRQACT-----------ALIDQLEQPIRLEP 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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