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Conserved domains on  [gi|512669463|ref|WP_016471695|]
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MULTISPECIES: beta/gamma crystallin domain-containing protein [Streptomyces]

Protein Classification

Crystall_2 domain-containing protein( domain architecture ID 10557423)

Crystall_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Crystall_2 pfam09076
Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein ...
 48-117 3.54e-28

Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein nine beta-strands are connected by loop, and are separated into two sheets, each sheet forming the Greek key motif. The two Greek key motifs face each other in the global topology. The three-dimensional structure of the molecule is a 'sandwich'-shaped beta-barrel structure: hydrophobic side-chains are packed in the large interface area of the beta-sheets. In Streptomyces killer toxin-like protein domain confers a cytocidal effect to the toxin, causing cell death in both budding and fission yeasts, and morphological changes in yeasts and filamentous fungi. This family also includes chitin-biding antifungal proteins.


:

Pssm-ID: 370280  Cd Length: 69  Bit Score: 97.54  E-value: 3.54e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512669463   48 IWSHLNGRDSVdCYANRGKTNFGGWWVDKISTGNNDVKYYDANGDVVKINRHKVISFPNRPPKVKAIEIL 117
Cdd:pfam09076   1 IRTHLNGGTSR-CFANAGVTAVGIYNVDRISTGNNVVTYNDANGDLVKTRRLTPITHPNRPSVVRVIEIL 69
 
Name Accession Description Interval E-value
Crystall_2 pfam09076
Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein ...
 48-117 3.54e-28

Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein nine beta-strands are connected by loop, and are separated into two sheets, each sheet forming the Greek key motif. The two Greek key motifs face each other in the global topology. The three-dimensional structure of the molecule is a 'sandwich'-shaped beta-barrel structure: hydrophobic side-chains are packed in the large interface area of the beta-sheets. In Streptomyces killer toxin-like protein domain confers a cytocidal effect to the toxin, causing cell death in both budding and fission yeasts, and morphological changes in yeasts and filamentous fungi. This family also includes chitin-biding antifungal proteins.


Pssm-ID: 370280  Cd Length: 69  Bit Score: 97.54  E-value: 3.54e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512669463   48 IWSHLNGRDSVdCYANRGKTNFGGWWVDKISTGNNDVKYYDANGDVVKINRHKVISFPNRPPKVKAIEIL 117
Cdd:pfam09076   1 IRTHLNGGTSR-CFANAGVTAVGIYNVDRISTGNNVVTYNDANGDLVKTRRLTPITHPNRPSVVRVIEIL 69
 
Name Accession Description Interval E-value
Crystall_2 pfam09076
Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein ...
 48-117 3.54e-28

Beta/Gamma crystallin; Members of this family assume a beta-gamma-crystallin fold, wherein nine beta-strands are connected by loop, and are separated into two sheets, each sheet forming the Greek key motif. The two Greek key motifs face each other in the global topology. The three-dimensional structure of the molecule is a 'sandwich'-shaped beta-barrel structure: hydrophobic side-chains are packed in the large interface area of the beta-sheets. In Streptomyces killer toxin-like protein domain confers a cytocidal effect to the toxin, causing cell death in both budding and fission yeasts, and morphological changes in yeasts and filamentous fungi. This family also includes chitin-biding antifungal proteins.


Pssm-ID: 370280  Cd Length: 69  Bit Score: 97.54  E-value: 3.54e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 512669463   48 IWSHLNGRDSVdCYANRGKTNFGGWWVDKISTGNNDVKYYDANGDVVKINRHKVISFPNRPPKVKAIEIL 117
Cdd:pfam09076   1 IRTHLNGGTSR-CFANAGVTAVGIYNVDRISTGNNVVTYNDANGDLVKTRRLTPITHPNRPSVVRVIEIL 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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