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Conserved domains on  [gi|301616570|ref|XP_002937728|]
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RNA polymerase I-specific transcription initiation factor RRN3 [Xenopus tropicalis]

Protein Classification

RNA polymerase I-specific transcription initiation factor RRN3 family protein( domain architecture ID 10526375)

RNA polymerase I-specific transcription initiation factor RRN3 family protein similar to human RRN3 that is required for efficient transcription initiation by RNA polymerase I, and for the formation of the competent preinitiation complex (PIC).

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 31-550 1.32e-151

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


:

Pssm-ID: 461623  Cd Length: 548  Bit Score: 447.83  E-value: 1.32e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570   31 SKGDVGDFELLKHQLS-----DPEIKDVQLLNWLHEFRSCITYLTKDYEQLVSIVLKLPWLNRSKEVVEEYLSFLGNLVS 105
Cdd:pfam05327  20 EKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLGVLAS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  106 AQTVYLRSCLSMIISHFVPARViirdgdVDISDSDDEDEDIISTFNTCHRALQIIAKYVPSAPRFLMPILVEKFPYTNKS 185
Cdd:pfam05327 100 AHPKYLSLVLSMLVSNFTPQPE------SSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLPILSRKFPHKRDS 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  186 ARTLECYVHNLLRISIYFPTLRLEILELVVEKLLKMDVSAsrQN-IEEAEESAYQGGGEQ------NKEEGLFNMDEDL- 257
Cdd:pfam05327 174 KKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVEI--QVeLEDLDDDEDEELLEQldedddDDDDDDSDDDSDSs 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  258 -QEMTTTSVVNETMA----HPVAERLDILILTLCSYIKDVCLTNGALDLN--KTKDMYRDLLAVFDKLILPTHASCHVQY 330
Cdd:pfam05327 252 dDGLDDDEEDDEVQRikkiKELVEKLDAILDLLFEHLDSKFSSGSPEELNegEGVEVFNTLLSLFKSTILPTYRSRHTQF 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  331 FMFYICSFRLGIAEAFVEHLWKKLQNPNNPPVIRQAAANYIGSFLARAKFIPLVTVKACLDLLVNWLHGYIDNQDAGSRA 410
Cdd:pfam05327 332 LLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDEREEECRG 411

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  411 yCDVTVHGPFYAACQAVFYSFIFRHNQFL---EGNMRKGLAYLQNLN--LERIVMCQLNPLKICLPSVVNFFAAITRKYQ 485
Cdd:pfam05327 412 -PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFARIAHHLQ 490

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301616570  486 LVFCYTIIERNNrqmipiiRSSTGGDSVQVSFNPLDSFFPFDPCILKRCKKLMDPFYQVWEESNT 550
Cdd:pfam05327 491 FAYCFSIIESNK-------REETAGTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVAG 548
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 31-550 1.32e-151

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 447.83  E-value: 1.32e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570   31 SKGDVGDFELLKHQLS-----DPEIKDVQLLNWLHEFRSCITYLTKDYEQLVSIVLKLPWLNRSKEVVEEYLSFLGNLVS 105
Cdd:pfam05327  20 EKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLGVLAS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  106 AQTVYLRSCLSMIISHFVPARViirdgdVDISDSDDEDEDIISTFNTCHRALQIIAKYVPSAPRFLMPILVEKFPYTNKS 185
Cdd:pfam05327 100 AHPKYLSLVLSMLVSNFTPQPE------SSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLPILSRKFPHKRDS 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  186 ARTLECYVHNLLRISIYFPTLRLEILELVVEKLLKMDVSAsrQN-IEEAEESAYQGGGEQ------NKEEGLFNMDEDL- 257
Cdd:pfam05327 174 KKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVEI--QVeLEDLDDDEDEELLEQldedddDDDDDDSDDDSDSs 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  258 -QEMTTTSVVNETMA----HPVAERLDILILTLCSYIKDVCLTNGALDLN--KTKDMYRDLLAVFDKLILPTHASCHVQY 330
Cdd:pfam05327 252 dDGLDDDEEDDEVQRikkiKELVEKLDAILDLLFEHLDSKFSSGSPEELNegEGVEVFNTLLSLFKSTILPTYRSRHTQF 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  331 FMFYICSFRLGIAEAFVEHLWKKLQNPNNPPVIRQAAANYIGSFLARAKFIPLVTVKACLDLLVNWLHGYIDNQDAGSRA 410
Cdd:pfam05327 332 LLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDEREEECRG 411

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  411 yCDVTVHGPFYAACQAVFYSFIFRHNQFL---EGNMRKGLAYLQNLN--LERIVMCQLNPLKICLPSVVNFFAAITRKYQ 485
Cdd:pfam05327 412 -PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFARIAHHLQ 490

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301616570  486 LVFCYTIIERNNrqmipiiRSSTGGDSVQVSFNPLDSFFPFDPCILKRCKKLMDPFYQVWEESNT 550
Cdd:pfam05327 491 FAYCFSIIESNK-------REETAGTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVAG 548
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 31-550 1.32e-151

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 447.83  E-value: 1.32e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570   31 SKGDVGDFELLKHQLS-----DPEIKDVQLLNWLHEFRSCITYLTKDYEQLVSIVLKLPWLNRSKEVVEEYLSFLGNLVS 105
Cdd:pfam05327  20 EKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLGVLAS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  106 AQTVYLRSCLSMIISHFVPARViirdgdVDISDSDDEDEDIISTFNTCHRALQIIAKYVPSAPRFLMPILVEKFPYTNKS 185
Cdd:pfam05327 100 AHPKYLSLVLSMLVSNFTPQPE------SSGRLPGYPPVTRREVYERVHEALKYILRLIPTAPSVLLPILSRKFPHKRDS 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  186 ARTLECYVHNLLRISIYFPTLRLEILELVVEKLLKMDVSAsrQN-IEEAEESAYQGGGEQ------NKEEGLFNMDEDL- 257
Cdd:pfam05327 174 KKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDVEI--QVeLEDLDDDEDEELLEQldedddDDDDDDSDDDSDSs 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  258 -QEMTTTSVVNETMA----HPVAERLDILILTLCSYIKDVCLTNGALDLN--KTKDMYRDLLAVFDKLILPTHASCHVQY 330
Cdd:pfam05327 252 dDGLDDDEEDDEVQRikkiKELVEKLDAILDLLFEHLDSKFSSGSPEELNegEGVEVFNTLLSLFKSTILPTYRSRHTQF 331

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  331 FMFYICSFRLGIAEAFVEHLWKKLQNPNNPPVIRQAAANYIGSFLARAKFIPLVTVKACLDLLVNWLHGYIDNQDAGSRA 410
Cdd:pfam05327 332 LLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDEREEECRG 411

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301616570  411 yCDVTVHGPFYAACQAVFYSFIFRHNQFL---EGNMRKGLAYLQNLN--LERIVMCQLNPLKICLPSVVNFFAAITRKYQ 485
Cdd:pfam05327 412 -PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFARIAHHLQ 490

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301616570  486 LVFCYTIIERNNrqmipiiRSSTGGDSVQVSFNPLDSFFPFDPCILKRCKKLMDPFYQVWEESNT 550
Cdd:pfam05327 491 FAYCFSIIESNK-------REETAGTATGQEFEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVAG 548
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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