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Conserved domains on  [gi|389630122|ref|XP_003712714|]
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epoxide hydrolase 2 [Pyricularia oryzae 70-15]

Protein Classification

alpha/beta hydrolase( domain architecture ID 11427000)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Gene Ontology:  GO:0016787
PubMed:  12369917|19508187

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 17-147 1.28e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  17 EHKDVQVNGRTYHYMLARPPAgaepkATILLVHGFPDLGLGWRHQVPVLAAqGFQVVVPDMLGYGGTDAPQDvePYRHKS 96
Cdd:COG0596    3 TPRFVTVDGVRLHYREAGPDG-----PPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAG--GYTLDD 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 389630122  97 IIDDLLALLDSQDLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:COG0596   75 LADDLAALLDALGL---------ERVVLVGHSMGGMVALELAARHPERVAG 116
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 44-345 2.69e-20

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member pfam00561:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 245  Bit Score: 88.72  E-value: 2.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   44 TILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDsqdlivPLGPsreRRVV 123
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILE------ALGL---EKVN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  124 LGGHDWGGQIVWRFTEWYPERIAATFSVCTPffPPMPSFIDlstlTQIIPSFKYQLQFaseevvDRTTGPDGKPSRAVIR 203
Cdd:pfam00561  73 LVGHSMGGLIALAYAAKYPDRVKALVLLGAL--DPPHELDE----ADRFILALFPGFF------DGFVADFAPNPLGRLV 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  204 DFLNAlWGGAGTIQAADAPKGFTAAEGVNFSIIKdlpqaqlMSVEELDFYADQYSRNGMRGPTNWYRlrklnfedeltli 283
Cdd:pfam00561 141 AKLLA-LLLLRLRLLKALPLLNKRFPSGDYALAK-------SLVTGALLFIETWSTELRAKFLGRLD------------- 199

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 389630122  284 errqkqaeetgdepkikTPSLFISASRDVALPPAMSANMDMCFESLTRGHV-DASHWALVEAA 345
Cdd:pfam00561 200 -----------------EPTLIIWGDQDPLVPPQALEKLAQLFPNARLVVIpDAGHFAFLEGP 245
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 17-147 1.28e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  17 EHKDVQVNGRTYHYMLARPPAgaepkATILLVHGFPDLGLGWRHQVPVLAAqGFQVVVPDMLGYGGTDAPQDvePYRHKS 96
Cdd:COG0596    3 TPRFVTVDGVRLHYREAGPDG-----PPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAG--GYTLDD 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 389630122  97 IIDDLLALLDSQDLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:COG0596   75 LADDLAALLDALGL---------ERVVLVGHSMGGMVALELAARHPERVAG 116
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 44-345 2.69e-20

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 88.72  E-value: 2.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   44 TILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDsqdlivPLGPsreRRVV 123
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILE------ALGL---EKVN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  124 LGGHDWGGQIVWRFTEWYPERIAATFSVCTPffPPMPSFIDlstlTQIIPSFKYQLQFaseevvDRTTGPDGKPSRAVIR 203
Cdd:pfam00561  73 LVGHSMGGLIALAYAAKYPDRVKALVLLGAL--DPPHELDE----ADRFILALFPGFF------DGFVADFAPNPLGRLV 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  204 DFLNAlWGGAGTIQAADAPKGFTAAEGVNFSIIKdlpqaqlMSVEELDFYADQYSRNGMRGPTNWYRlrklnfedeltli 283
Cdd:pfam00561 141 AKLLA-LLLLRLRLLKALPLLNKRFPSGDYALAK-------SLVTGALLFIETWSTELRAKFLGRLD------------- 199

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 389630122  284 errqkqaeetgdepkikTPSLFISASRDVALPPAMSANMDMCFESLTRGHV-DASHWALVEAA 345
Cdd:pfam00561 200 -----------------EPTLIIWGDQDPLVPPQALEKLAQLFPNARLVVIpDAGHFAFLEGP 245
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 29-147 3.61e-14

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 72.31  E-value: 3.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  29 HYMLARPPAGAepkaTILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDSQ 108
Cdd:PRK00870  37 HYVDEGPADGP----PVLLLHGEPSWSYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTRREDYTYARHVEWMRSWFEQL 112

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 389630122 109 DLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:PRK00870 113 DL---------TDVTLVCQDWGGLIGLRLAAEHPDRFAR 142
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 39-147 2.65e-08

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 54.14  E-value: 2.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   39 AEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQ-DVEPYRHksIIDDLLALLdsqDLIVPLGPs 117
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRgHVPSFDD--YVDDLDTFV---DKIREEHP- 74

                          90       100       110
                  ....*....|....*....|....*....|
gi 389630122  118 rERRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:pfam12146  75 -GLPLFLLGHSMGGLIAALYALRYPDKVDG 103
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 17-147 1.28e-24

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 100.08  E-value: 1.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  17 EHKDVQVNGRTYHYMLARPPAgaepkATILLVHGFPDLGLGWRHQVPVLAAqGFQVVVPDMLGYGGTDAPQDvePYRHKS 96
Cdd:COG0596    3 TPRFVTVDGVRLHYREAGPDG-----PPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAG--GYTLDD 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 389630122  97 IIDDLLALLDSQDLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:COG0596   75 LADDLAALLDALGL---------ERVVLVGHSMGGMVALELAARHPERVAG 116
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 44-345 2.69e-20

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 88.72  E-value: 2.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   44 TILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDsqdlivPLGPsreRRVV 123
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILE------ALGL---EKVN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  124 LGGHDWGGQIVWRFTEWYPERIAATFSVCTPffPPMPSFIDlstlTQIIPSFKYQLQFaseevvDRTTGPDGKPSRAVIR 203
Cdd:pfam00561  73 LVGHSMGGLIALAYAAKYPDRVKALVLLGAL--DPPHELDE----ADRFILALFPGFF------DGFVADFAPNPLGRLV 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  204 DFLNAlWGGAGTIQAADAPKGFTAAEGVNFSIIKdlpqaqlMSVEELDFYADQYSRNGMRGPTNWYRlrklnfedeltli 283
Cdd:pfam00561 141 AKLLA-LLLLRLRLLKALPLLNKRFPSGDYALAK-------SLVTGALLFIETWSTELRAKFLGRLD------------- 199

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 389630122  284 errqkqaeetgdepkikTPSLFISASRDVALPPAMSANMDMCFESLTRGHV-DASHWALVEAA 345
Cdd:pfam00561 200 -----------------EPTLIIWGDQDPLVPPQALEKLAQLFPNARLVVIpDAGHFAFLEGP 245
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
24-147 3.37e-16

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 76.58  E-value: 3.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  24 NGRTYHYMLARPPAgaEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPyRHKSIIDDLLA 103
Cdd:COG2267   12 DGLRLRGRRWRPAG--SPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVD-SFDDYVDDLRA 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 389630122 104 LLDSqdlivpLGPSRERRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:COG2267   89 ALDA------LRARPGLPVVLLGHSMGGLIALLYAARYPDRVAG 126
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 29-147 3.61e-14

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 72.31  E-value: 3.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  29 HYMLARPPAGAepkaTILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDSQ 108
Cdd:PRK00870  37 HYVDEGPADGP----PVLLLHGEPSWSYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTRREDYTYARHVEWMRSWFEQL 112

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 389630122 109 DLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:PRK00870 113 DL---------TDVTLVCQDWGGLIGLRLAAEHPDRFAR 142
PRK05855 PRK05855
SDR family oxidoreductase;
38-154 3.72e-14

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 73.48  E-value: 3.72e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  38 GAEPKATILLVHGFPDLGLGWRHQVPVLAAQgFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDSqdlivpLGPs 117
Cdd:PRK05855  21 GDPDRPTVVLVHGYPDNHEVWDGVAPLLADR-FRVVAYDVRGAGRSSAPKRTAAYTLARLADDFAAVIDA------VSP- 92

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 389630122 118 rERRVVLGGHDWGGQIVWRFT--EWYPERIAATFSVCTP 154
Cdd:PRK05855  93 -DRPVHLLAHDWGSIQGWEAVtrPRAAGRIASFTSVSGP 130
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
24-189 3.39e-13

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 68.50  E-value: 3.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  24 NGRTYHYMLARPPaGAEPKATILLVHGFP-DLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYrhksiiDDLL 102
Cdd:COG1506    6 DGTTLPGWLYLPA-DGKKYPVVVYVHGGPgSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEV------DDVL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122 103 ALLD---SQDLIVPlgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAATFSVCtpffppmpSFIDLSTLTQIIPSFKYQL 179
Cdd:COG1506   79 AAIDylaARPYVDP------DRIGIYGHSYGGYMALLAAARHPDRFKAAVALA--------GVSDLRSYYGTTREYTERL 144

                        170
                 ....*....|
gi 389630122 180 QFASEEVVDR 189
Cdd:COG1506  145 MGGPWEDPEA 154
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
24-152 1.02e-08

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 54.97  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  24 NGRTYHYMLARPpAGAEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQD-----VEPYRHKSII 98
Cdd:COG0412   12 DGVTLPGYLARP-AGGGPRPGVVVLHEIFGLNPHIRDVARRLAAAGYVVLAPDLYGRGGPGDDPDearalMGALDPELLA 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 389630122  99 DDLLALLD---SQDLIVPlgpsreRRVVLGGHDWGGQIVWRFTEWYPeRIAATFSVC 152
Cdd:COG0412   91 ADLRAALDwlkAQPEVDA------GRVGVVGFCFGGGLALLAAARGP-DLAAAVSFY 140
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 17-147 1.72e-08

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 55.00  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  17 EHKDVQVNGRTYHYmlaRPPAGAEPkatILLVHGFPDLGLGWRHQVPVLAAQGfQVVVPDMLGYGGTDAPqDVEpYRHKS 96
Cdd:PRK03592   8 EMRRVEVLGSRMAY---IETGEGDP---IVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKP-DID-YTFAD 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 389630122  97 IIDDLLALLDSQDLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:PRK03592  79 HARYLDAWFDALGL---------DDVVLVGHDWGSALGFDWAARHPDRVRG 120
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 39-147 2.65e-08

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 54.14  E-value: 2.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   39 AEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQ-DVEPYRHksIIDDLLALLdsqDLIVPLGPs 117
Cdd:pfam12146   1 GEPRAVVVLVHGLGEHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRgHVPSFDD--YVDDLDTFV---DKIREEHP- 74

                          90       100       110
                  ....*....|....*....|....*....|
gi 389630122  118 rERRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:pfam12146  75 -GLPLFLLGHSMGGLIAALYALRYPDKVDG 103
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 45-220 7.11e-07

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 49.39  E-value: 7.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122   45 ILLVHGFPDlglgWRHQVPVLAAQGFQVVVPDMLGYGGTD-APQDVEPYRhksiidDLLALLDSQDlivplgpsRERRVV 123
Cdd:pfam12697   1 VVLVHGAGL----SAAPLAALLAAGVAVLAPDLPGHGSSSpPPLDLADLA------DLAALLDELG--------AARPVV 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  124 LGGHDWGGQIVWRFTEWYPerIAATFSVCTPFFPPMPSFIDLSTLTQIIPSFKYQLQFASEEVVDRTTGPDGKPSRAVIR 203
Cdd:pfam12697  63 LVGHSLGGAVALAAAAAAL--VVGVLVAPLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAAAL 140

                         170
                  ....*....|....*..
gi 389630122  204 DFLNALWGGAGTIQAAD 220
Cdd:pfam12697 141 ARLAALLAALALLPLAA 157
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 37-87 1.93e-05

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 46.03  E-value: 1.93e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 389630122  37 AGAEPKATILLVHGFPDLGLGWRHQVPVLaAQGFQVVVPDMLGYGGTDAPQ 87
Cdd:PLN03084 122 SGSNNNPPVLLIHGFPSQAYSYRKVLPVL-SKNYHAIAFDWLGFGFSDKPQ 171
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 11-177 2.08e-05

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 45.29  E-value: 2.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  11 PNDPRVEHKDVQV---NGRTYHYMLARPPAGAEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTD-AP 86
Cdd:COG1073    3 PPSDKVNKEDVTFksrDGIKLAGDLYLPAGASKKYPAVVVAHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGESEgEP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  87 QDVEPYRhksiIDDLLALLD--SQDLIVPlgpsrERRVVLGGHDWGGQIVWRFTEWYPeRIAATFSVCT----------- 153
Cdd:COG1073   83 REEGSPE----RRDARAAVDylRTLPGVD-----PERIGLLGISLGGGYALNAAATDP-RVKAVILDSPftsledlaaqr 152

                        170       180       190
                 ....*....|....*....|....*....|...
gi 389630122 154 ---------PFFPPMPSFIDLSTLTQIIPSFKY 177
Cdd:COG1073  153 akeargaylPGVPYLPNVRLASLLNDEFDPLAK 185
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 12-147 3.13e-05

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 45.32  E-value: 3.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  12 NDPRVEHKDVQVNGRTYHYmLARPPAGAEPkatILLVHGFPDLGLGWRHQVPVLAAqGFQVVVPDMLGYGGTDapQDVEP 91
Cdd:PRK14875 105 EDAGPAPRKARIGGRTVRY-LRLGEGDGTP---VVLIHGFGGDLNNWLFNHAALAA-GRPVIALDLPGHGASS--KAVGA 177

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 389630122  92 YRHKSIIDDLLALLDSQDLivplgpsreRRVVLGGHDWGGQIVWRFTEWYPERIAA 147
Cdd:PRK14875 178 GSLDELAAAVLAFLDALGI---------ERAHLVGHSMGGAVALRLAARAPQRVAS 224
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 45-155 2.89e-04

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 39.81  E-value: 2.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  45 ILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDmlgYGGTDAPqdvepyrhksiIDDLLALLDSQ-DLIvpLGPSRERRVV 123
Cdd:COG1075    8 VVLVHGLGGSAASWAPLAPRLRAAGYPVYALN---YPSTNGS-----------IEDSAEQLAAFvDAV--LAATGAEKVD 71

                         90       100       110
                 ....*....|....*....|....*....|....
gi 389630122 124 LGGHDWGGQIVWRFTEWY--PERIAATFSVCTPF 155
Cdd:COG1075   72 LVGHSMGGLVARYYLKRLggAAKVARVVTLGTPH 105
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 30-86 5.13e-04

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 41.75  E-value: 5.13e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 389630122  30 YMLARPPAGAEPKATILLVHGFPDLGLGWRHQVPVLaAQGFQVVVPDMLGYGGTDAP 86
Cdd:PLN02679  76 YLVKGSPEVTSSGPPVLLVHGFGASIPHWRRNIGVL-AKNYTVYAIDLLGFGASDKP 131
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 45-86 9.95e-04

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 40.49  E-value: 9.95e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 389630122  45 ILLVHGFPDLGLGWRHQVPVLAAQGfQVVVPDMLGYGGTDAP 86
Cdd:PLN02824  32 LVLVHGFGGNADHWRKNTPVLAKSH-RVYAIDLLGYGYSDKP 72
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
45-176 1.31e-03

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 39.92  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 389630122  45 ILLVHGF---PDLGLGWRHQvpvLAAQGFQVVVPDMLGYGGTdaPQDVEPYRHKSIIDDLLALLDsqdlivpLGPSRERR 121
Cdd:COG1647   18 VLLLHGFtgsPAEMRPLAEA---LAKAGYTVYAPRLPGHGTS--PEDLLKTTWEDWLEDVEEAYE-------ILKAGYDK 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 389630122 122 VVLGGHDWGGQIVWRFTEWYPErIAATFSVCTPFFPPMPSFIDLSTLTQIIPSFK 176
Cdd:COG1647   86 VIVIGLSMGGLLALLLAARYPD-VAGLVLLSPALKIDDPSAPLLPLLKYLARSLR 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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