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Conserved domains on  [gi|544451095|ref|XP_005562973|]
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PREDICTED: clusterin isoform X1 [Macaca fascicularis]

Protein Classification

Clusterin domain-containing protein( domain architecture ID 12014179)

Clusterin domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Clusterin pfam01093
Clusterin;
116-531 0e+00

Clusterin;


:

Pssm-ID: 460061 [Multi-domain]  Cd Length: 418  Bit Score: 609.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  116 ELQEMSDQGSKYLNKEIQNAVNGVKEIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKEFPGVCNETMMAL 195
Cdd:pfam01093   1 ELKELSEAGEKYVDEEVKNALIGVKQMKTMMERREEEHKKLMKSLEKSKEKKEEALKLAKEVEEKLEEEEEVCNESMKAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  196 WEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWINGDRIDSLL--ENDRQQTHMMDVMQDRFSRASSIM 273
Cdd:pfam01093  81 WEECKPCLESTCMKFYTRTCRSGSGLVGRQLEEFFNRISPFSFWINGDRIDDLLvnEEDQEQDAQLVQMEDSFSQLSSDV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  274 DELFQDRFFAREPQDSYHFLPFSLPHRRPHFFF-----------PKSRIVRSlmpfspyepLNFHAMFQPFLEMIHEAQQ 342
Cdd:pfam01093 161 DSLFNRSFKVFKQMQQEFDQAFQSYFMSDLDLTepyffpskeptRKSRFLRS---------WGFPNVFQPFFDFSRSVFE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  343 AMDIHFHSPAFQHPPTEFIREG-DDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCsannPAQAQLRRELSESLQVAE 421
Cdd:pfam01093 232 SFSAVITETLDSDPGGLFSKELpGQDRMLCRELRRNSSGCLKFQDRCEKCQEILSVDC----PSVPELHEELEEALQLAE 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  422 RLTRKYNELLQSYQWKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYlRVTTVASHTSDS-GVPSGVTEVVVKLFDSDP 500
Cdd:pfam01093 308 VSTQQYDELLQIVQHHMEDTSSLLDQMNEQFGWVSELANQTQGPENIF-NVTTVVPKSSEGeSSKQGDTKVEVSILDSPP 386
                         410       420       430
                  ....*....|....*....|....*....|.
gi 544451095  501 ITVTVPVEVSRKNPKFMETVVEKALQEYRKK 531
Cdd:pfam01093 387 FTLTVPGELSWDDPKFIEYVAQKALQHYKEH 417
 
Name Accession Description Interval E-value
Clusterin pfam01093
Clusterin;
116-531 0e+00

Clusterin;


Pssm-ID: 460061 [Multi-domain]  Cd Length: 418  Bit Score: 609.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  116 ELQEMSDQGSKYLNKEIQNAVNGVKEIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKEFPGVCNETMMAL 195
Cdd:pfam01093   1 ELKELSEAGEKYVDEEVKNALIGVKQMKTMMERREEEHKKLMKSLEKSKEKKEEALKLAKEVEEKLEEEEEVCNESMKAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  196 WEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWINGDRIDSLL--ENDRQQTHMMDVMQDRFSRASSIM 273
Cdd:pfam01093  81 WEECKPCLESTCMKFYTRTCRSGSGLVGRQLEEFFNRISPFSFWINGDRIDDLLvnEEDQEQDAQLVQMEDSFSQLSSDV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  274 DELFQDRFFAREPQDSYHFLPFSLPHRRPHFFF-----------PKSRIVRSlmpfspyepLNFHAMFQPFLEMIHEAQQ 342
Cdd:pfam01093 161 DSLFNRSFKVFKQMQQEFDQAFQSYFMSDLDLTepyffpskeptRKSRFLRS---------WGFPNVFQPFFDFSRSVFE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  343 AMDIHFHSPAFQHPPTEFIREG-DDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCsannPAQAQLRRELSESLQVAE 421
Cdd:pfam01093 232 SFSAVITETLDSDPGGLFSKELpGQDRMLCRELRRNSSGCLKFQDRCEKCQEILSVDC----PSVPELHEELEEALQLAE 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  422 RLTRKYNELLQSYQWKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYlRVTTVASHTSDS-GVPSGVTEVVVKLFDSDP 500
Cdd:pfam01093 308 VSTQQYDELLQIVQHHMEDTSSLLDQMNEQFGWVSELANQTQGPENIF-NVTTVVPKSSEGeSSKQGDTKVEVSILDSPP 386
                         410       420       430
                  ....*....|....*....|....*....|.
gi 544451095  501 ITVTVPVEVSRKNPKFMETVVEKALQEYRKK 531
Cdd:pfam01093 387 FTLTVPGELSWDDPKFIEYVAQKALQHYKEH 417
CLa smart00035
CLUSTERIN alpha chain;
314-529 2.00e-147

CLUSTERIN alpha chain;


Pssm-ID: 128350  Cd Length: 216  Bit Score: 421.88  E-value: 2.00e-147
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   314 SLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCRE 393
Cdd:smart00035   1 NLMPFPQYWPLNFHDMFQPFFDMIHQAQQAMDTHLHRPPYQFPKQDFAEEHGDDRTVCKEIRHNSTGCLKMKDQCEKCQE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   394 ILSVDCSANNPAQAQLRRELSESLQVAERLTRKYNELLQSYQWKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYLRVT 473
Cdd:smart00035  81 ILSVDCSTNNPDQPQLRQELDESLQLAERFTQQYDQLLQSYQKKMLNTSSLLEQLNEQFGWVSQLANLTQGEDQYYLQVT 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 544451095   474 TVASHTSDSGVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVVEKALQEYR 529
Cdd:smart00035 161 TVPSHTSDSSVPSGTTKVVVKLFDSDPITLTIPEEVSADNPKFMETVAEKALQHYR 216
 
Name Accession Description Interval E-value
Clusterin pfam01093
Clusterin;
116-531 0e+00

Clusterin;


Pssm-ID: 460061 [Multi-domain]  Cd Length: 418  Bit Score: 609.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  116 ELQEMSDQGSKYLNKEIQNAVNGVKEIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKEFPGVCNETMMAL 195
Cdd:pfam01093   1 ELKELSEAGEKYVDEEVKNALIGVKQMKTMMERREEEHKKLMKSLEKSKEKKEEALKLAKEVEEKLEEEEEVCNESMKAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  196 WEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWINGDRIDSLL--ENDRQQTHMMDVMQDRFSRASSIM 273
Cdd:pfam01093  81 WEECKPCLESTCMKFYTRTCRSGSGLVGRQLEEFFNRISPFSFWINGDRIDDLLvnEEDQEQDAQLVQMEDSFSQLSSDV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  274 DELFQDRFFAREPQDSYHFLPFSLPHRRPHFFF-----------PKSRIVRSlmpfspyepLNFHAMFQPFLEMIHEAQQ 342
Cdd:pfam01093 161 DSLFNRSFKVFKQMQQEFDQAFQSYFMSDLDLTepyffpskeptRKSRFLRS---------WGFPNVFQPFFDFSRSVFE 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  343 AMDIHFHSPAFQHPPTEFIREG-DDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCsannPAQAQLRRELSESLQVAE 421
Cdd:pfam01093 232 SFSAVITETLDSDPGGLFSKELpGQDRMLCRELRRNSSGCLKFQDRCEKCQEILSVDC----PSVPELHEELEEALQLAE 307
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095  422 RLTRKYNELLQSYQWKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYlRVTTVASHTSDS-GVPSGVTEVVVKLFDSDP 500
Cdd:pfam01093 308 VSTQQYDELLQIVQHHMEDTSSLLDQMNEQFGWVSELANQTQGPENIF-NVTTVVPKSSEGeSSKQGDTKVEVSILDSPP 386
                         410       420       430
                  ....*....|....*....|....*....|.
gi 544451095  501 ITVTVPVEVSRKNPKFMETVVEKALQEYRKK 531
Cdd:pfam01093 387 FTLTVPGELSWDDPKFIEYVAQKALQHYKEH 417
CLa smart00035
CLUSTERIN alpha chain;
314-529 2.00e-147

CLUSTERIN alpha chain;


Pssm-ID: 128350  Cd Length: 216  Bit Score: 421.88  E-value: 2.00e-147
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   314 SLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCRE 393
Cdd:smart00035   1 NLMPFPQYWPLNFHDMFQPFFDMIHQAQQAMDTHLHRPPYQFPKQDFAEEHGDDRTVCKEIRHNSTGCLKMKDQCEKCQE 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   394 ILSVDCSANNPAQAQLRRELSESLQVAERLTRKYNELLQSYQWKMLNTSSLLEQLNEQFNWVSQLANLTQGEDQYYLRVT 473
Cdd:smart00035  81 ILSVDCSTNNPDQPQLRQELDESLQLAERFTQQYDQLLQSYQKKMLNTSSLLEQLNEQFGWVSQLANLTQGEDQYYLQVT 160
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 544451095   474 TVASHTSDSGVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVVEKALQEYR 529
Cdd:smart00035 161 TVPSHTSDSSVPSGTTKVVVKLFDSDPITLTIPEEVSADNPKFMETVAEKALQHYR 216
CLb smart00030
CLUSTERIN Beta chain;
109-313 1.08e-133

CLUSTERIN Beta chain;


Pssm-ID: 128345  Cd Length: 206  Bit Score: 386.48  E-value: 1.08e-133
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   109 DQTVSDNELQEMSDQGSKYLNKEIQNAVNGVKEIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKEFPGVC 188
Cdd:smart00030   1 DKTVSDNELQEMSTQGSKYINKEIKNALKGVKQIKTLIEKTNKERKSLLSTLEEAKKKKEEALKDTRESEEKLKESQGVC 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 544451095   189 NETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWINGDRIDSLLENDRQQTHMMDVMQDRFSR 268
Cdd:smart00030  81 NETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQSHVLDVMEDSFSR 160
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 544451095   269 ASSIMDELFQDRFFAREPQDSYHFLPFSLPHRR-PHFFFPKSRIVR 313
Cdd:smart00030 161 ASSIVDELFQDRFFTREPQDTTFYSPFSSPHRRtEPFFFPKSRLAR 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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