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solute carrier family 12 member 6 isoform X2 [Rattus norvegicus]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
94-1135
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1351.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 94 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKSPQM G T 172
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 173 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 252
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 253 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIF R SD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 332
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLL R EN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 333 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhldicsktkevnnmtipsklwgffcnssqffnatcdey F VH N 412
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 413 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgnlnheyvladitts F TL L V GIFFPSVTGI M AG S N R SG 492
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 493 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 551
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 552 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 630
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 631 L S M FFL MC Y LFV N LA C ALQT LLR T P H WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 710
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 711 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 790
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 791 D A L AAE QT I KHLM E AE KVK G F CQL VVA AK L K EG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 870
Cdd:TIGR00930 621 E A Q AAE AK I QTWL E KN KVK A F YAV VVA DD L R EG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 871 AHLA LL V AK N VSFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 912
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 913 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 992
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 993 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkvksmegf QD L lnmrpd QSNVR RMHTA 1072
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564342248 1073 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1135
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
94-1135
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1351.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 94 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKSPQM G T 172
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 173 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 252
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 253 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIF R SD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 332
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLL R EN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 333 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhldicsktkevnnmtipsklwgffcnssqffnatcdey F VH N 412
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 413 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgnlnheyvladitts F TL L V GIFFPSVTGI M AG S N R SG 492
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 493 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 551
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 552 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 630
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 631 L S M FFL MC Y LFV N LA C ALQT LLR T P H WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 710
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 711 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 790
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 791 D A L AAE QT I KHLM E AE KVK G F CQL VVA AK L K EG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 870
Cdd:TIGR00930 621 E A Q AAE AK I QTWL E KN KVK A F YAV VVA DD L R EG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 871 AHLA LL V AK N VSFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 912
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 913 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 992
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 993 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkvksmegf QD L lnmrpd QSNVR RMHTA 1072
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564342248 1073 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1135
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
175-745
3.74e-48
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 179.05
E-value: 3.74e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 175 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 254
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 255 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I FRSD dalkesaamlnnmr V Y G TA FLVL MVLVVFI GV RYVNKFASL F 332
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I PYLW -------------- V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 333 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhldicsktkevnnmtipsklwgffcn SSQFFNATCDEY F V 410
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ------------------------------------- FRYLGDNGGKNN F P 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 411 HNNVTSI qgipgl A S GII tenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvg I F F PSV TGI MAGSNR 490
Cdd:pfam00324 186 PGFGKGF ------ I S VFV ----------------------------------------------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 491 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 566
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 567 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I AS ld L VAP I LSM F F L MCYLFVN L AC 646
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L AS -- L NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 647 ALQTL L RTPHW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 726
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 564342248 727 L LR L EEGPP H T KNW R PQLL 745
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
183-705
1.67e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 140.80
E-value: 1.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 183 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 259
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 260 GTTF A A A MYILGAIE i F L VYIV P RAAIF rsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 339
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 340 I L AIYAGAI k SS F A P PH F pvcmlgnrtlssrhldicsktkevnnmtipsklwgffcns SQ F FN A T cdeyfvhnnvtsi Q G 419
Cdd:COG0531 162 L L LFIVVGL - FA F D P AN F ---------------------------------------- TP F LP A G ------------- G G 187
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 420 IP G LASGI itenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllv GIF F PSV TG IM A GS N RSGDL K DAQK 499
Cdd:COG0531 188 LS G VLAAL ----------------------------------------------- ALA F FAF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 500 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 577
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 578 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 654
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 564342248 655 P HWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 705
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
94-1135
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1351.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 94 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKSPQM G T 172
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 173 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 252
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 253 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIF R SD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 332
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLL R EN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 333 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhldicsktkevnnmtipsklwgffcnssqffnatcdey F VH N 412
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 413 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgnlnheyvladitts F TL L V GIFFPSVTGI M AG S N R SG 492
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 493 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 551
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 552 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 630
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 631 L S M FFL MC Y LFV N LA C ALQT LLR T P H WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 710
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 711 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 790
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 791 D A L AAE QT I KHLM E AE KVK G F CQL VVA AK L K EG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 870
Cdd:TIGR00930 621 E A Q AAE AK I QTWL E KN KVK A F YAV VVA DD L R EG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 871 AHLA LL V AK N VSFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 912
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 913 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 992
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 993 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkvksmegf QD L lnmrpd QSNVR RMHTA 1072
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564342248 1073 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1135
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
175-745
3.74e-48
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 179.05
E-value: 3.74e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 175 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 254
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 255 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I FRSD dalkesaamlnnmr V Y G TA FLVL MVLVVFI GV RYVNKFASL F 332
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I PYLW -------------- V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 333 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhldicsktkevnnmtipsklwgffcn SSQFFNATCDEY F V 410
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ------------------------------------- FRYLGDNGGKNN F P 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 411 HNNVTSI qgipgl A S GII tenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllvg I F F PSV TGI MAGSNR 490
Cdd:pfam00324 186 PGFGKGF ------ I S VFV ----------------------------------------------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 491 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 566
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 567 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I AS ld L VAP I LSM F F L MCYLFVN L AC 646
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L AS -- L NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 647 ALQTL L RTPHW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 726
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 564342248 727 L LR L EEGPP H T KNW R PQLL 745
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
183-705
1.67e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 140.80
E-value: 1.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 183 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 259
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 260 GTTF A A A MYILGAIE i F L VYIV P RAAIF rsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 339
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 340 I L AIYAGAI k SS F A P PH F pvcmlgnrtlssrhldicsktkevnnmtipsklwgffcns SQ F FN A T cdeyfvhnnvtsi Q G 419
Cdd:COG0531 162 L L LFIVVGL - FA F D P AN F ---------------------------------------- TP F LP A G ------------- G G 187
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 420 IP G LASGI itenlwsnylpkgeiiekpsakssdvlgnlnheyvladittsftllv GIF F PSV TG IM A GS N RSGDL K DAQK 499
Cdd:COG0531 188 LS G VLAAL ----------------------------------------------- ALA F FAF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 500 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 577
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 578 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 654
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 564342248 655 P HWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 705
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
SLC12
pfam03522 Solute carrier family 12;
759-1135
4.62e-30
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 124.27
E-value: 4.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 759 P R L LT FA SQLKAGKG L T I V G S V IV G NFLENYGDA L AAE qt IKHLMEAE K V K G F CQ LV VAAK L K EG ISH L I Q SC GLG GM K H 838
Cdd:pfam03522 2 P A L VD FA HLITKNVS L M I C G H V VK G RLSQKLRSE L QKK -- AYRWLRKR K I K A F YA LV DGDN L R EG AQA L L Q AS GLG KL K P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 839 N TVV MG WPNG WR QSE ------------ DA --------------------------------------------------- 855
Cdd:pfam03522 80 N ILL MG YKSD WR TCD keeleeyfnvih DA fdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 856 -- RAWKTFIGTVRVTTAAH L ALLV ------------------- AKNVSFFPSNV E -------- QF ---- SE G N IDVWW IV 902
Cdd:pfam03522 160 ns KQDDDKSKLSKKDSNLS L SPDK stknpsgkdssksdklkkk SPSIILRTASN E keilnnit QF qkkq KK G T IDVWW LY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 903 H DGG MLM LLP FL L KQHKV W RK C SI R I F TVAQLE D NSIQMKKDL A TF L YHL RI E - AEVE V V emhd S DI SAYTYER T LMMEQ 981
Cdd:pfam03522 240 D DGG LTL LLP YI L STRSK W SD C KL R V F ALGNRK D ELEEEQRNM A SL L SKF RI D y SDLT V I ---- P DI TKKPKKE T KKFFD 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 982 rs QMLRHM RL SKTERDR E aqlvkdrn S MLRL T sigsde D E E T E TYQ EK VH mtwtkdkymasrgqkvksmegfqdl LNM R p 1061
Cdd:pfam03522 316 -- ELIEPF RL HEDDKEE E -------- S AEKI T ------ D S E L E ALK EK TN ------------------------- RQL R - 353
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564342248 1062 dqsnvrrmhtavk L N E VIVNK S HE A K L VLLNM P G P PRNPEGDEN YM EF LE V LT EG L ERV LLVRG GGSE V I T I YS 1135
Cdd:pfam03522 354 ------------- L R E LLLEH S SD A N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPF LLVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
461-702
1.09e-14
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 77.74
E-value: 1.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 461 YVLA D ITTSFTLLVGIFFP S V TG IMAGS N R S GDL K da QKSI P IGTILAILTTSFV Y - L S N VVL FG AC - IEGVV L RDKF G D 538
Cdd:pfam13520 181 TFFP D GWPGVFAGFLGVLW S F TG FESAA N V S EEV K -- KRNV P KAIFIGVIIVGVL Y i L V N IAF FG VV p DDEIA L SSGL G Q 258
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 539 --- AVKGNLVVGTLSW pspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A I A K D NII PF L R V F GHSKAN G E P TW A LL LTA AIA 615
Cdd:pfam13520 259 vaa LLFQAVGGKWGAI ---- IV VI LLAL S LL GA VNTAIV GA S RLL Y A L A R D GVL PF S R F F AKVNKF G S P IR A II LTA ILS 334
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 616 ELGI L IAS L DLV A PI ---- LS MFFLMCYLFVNLACA L qt L LR TPHWRPRFRYYH W ALSFM G M s ICLALMFISSWYYAIVA 691
Cdd:pfam13520 335 LILL L LFL L SPA A YN alls LS AYGYLLSYLLPIIGL L -- I LR KKRPDLGRIPGR W PVAIF G I - LFSLFLIVALFFPPVGP 411
250
....*....|.
gi 564342248 692 MVIAGMI Y KY I 702
Cdd:pfam13520 412 ATGSSLN Y AI I 422
2A0308
TIGR00911 L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
492-691
7.50e-05
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273332 [Multi-domain]
Cd Length: 501
Bit Score: 46.66
E-value: 7.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 492 GDL K DAQKSI PI GT I LAILTTS F V Y - L S N VVL F GACIEGVV L RDKFGDAVK G NLVV G TL SW PS P wv IVI G sf F S TC G AGL 570
Cdd:TIGR00911 259 EEV K NPYRTL PI AI I ISMPIVT F I Y v L T N IAY F TVLSPEEL L ASLAVAVDF G ERLL G VM SW AM P -- ALV G -- L S CF G SVN 334
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342248 571 Q SL TGAP RL LQAIAKDNII P F L RVFG H S K AN g E P TWA LL LTAAIAE L GILIASLDLVAPIL S MFF lmc Y LF VN LA C A LQT 650
Cdd:TIGR00911 335 G SL FSSS RL FFVGGREGHL P S L LSMI H V K RL - T P LPS LL IVCTLTL L MLFSGDIYSLINLI S FAN --- W LF NA LA V A GLL 410
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 564342248 651 L LR -- T P HWRPRFR yyhwalsfmg MSICLALM F IS S WYYA I VA 691
Cdd:TIGR00911 411 W LR yk R P EMNRPIK ---------- VPLFFPVF F LL S CLFL I IL 443
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
