|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-395 |
4.22e-134 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 393.30 E-value: 4.22e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 1 MAVEQDMLIAVGPVKTQT-LQLANTDPLYP--DFSTTANNiCIDKTQPLWHNYFLCGFKGIQEHFG-----LTQLPGMNC 72
Cdd:PLN02521 74 MAIRQDTIVAIRRAEGSKkLRIANVNDKYTtcTFPADPDQ-EVDLANHKWGNYFICGYKGVFEFLKskgvdVGPPVGLDV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 73 LVDGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRA 152
Cdd:PLN02521 153 VVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVAQFTCKCERHIGTQSGGMDQAISIMAQQGVAKLIDFNPVRA 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 153 TDVKLPSGAVFVIANSCVEMNKAATSH--FNVRVMECRLAAKVLAKHKGLQWD----KVLRLEEVQSeLGISLEE----- 221
Cdd:PLN02521 233 TDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAVKLGMSAEeaisKVKTLSDVEG-LCVSFAGshgss 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 222 -MLLVTEDALHAEPYSREEICKCLGISLEELRTQilSPNTQGELT----FKLYQRAKHVYSEAARVLQFKQVCEAAPDNA 296
Cdd:PLN02521 312 dPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRAVHVYSEAKRVHAFRDTVSSSLSEE 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 297 VQL--LGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQgnmS 374
Cdd:PLN02521 390 EKLkkLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKFYK---S 466
|
410 420
....*....|....*....|....*...
gi 564342729 375 RLAREKHS-------LFATKPGGGALVF 395
Cdd:PLN02521 467 RIEKGVIKeedlglyVFASKPSSGAAIL 494
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-392 |
4.69e-66 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 214.63 E-value: 4.69e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 1 MAVEQDMLIAVGPVKTQTLQLANTDplYPD-FSTTANNICIDKTQPlWHNYFLCGFKGIQEHfGLtQLPGMNCLVDGNIP 79
Cdd:COG0153 44 AAIDRGTYAAARPRDDRKVRVYSAD--FDEeVEFDLDDLEPGEEDG-WANYVRGVAWALQER-GY-KLGGFDLVIDGDVP 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 80 PSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLP 158
Cdd:COG0153 119 LGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAEnEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLP 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 159 -SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKhkglqwdKVLRleEVqselgiSLEEmllvtedalhaepysr 237
Cdd:COG0153 199 lEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR--DV------TLED---------------- 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 238 eeickclgisLEELRTQILSPntqgeltfKLYQRAKHVYSEAARVLQFkqvCEAAPDNAVQLLGELMNQSHRSCRDMYEC 317
Cdd:COG0153 247 ----------LEAARARLGDE--------VLRRRARHVVTENQRVLEA---VEALRAGDLEAFGKLMNASHASLRDDYEV 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564342729 318 SCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQGnmsrlAREKHSLFATKPGGGA 392
Cdd:COG0153 306 SCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEK-----TGLEPDFYVVKPSDGA 376
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
2-368 |
2.40e-57 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 192.35 E-value: 2.40e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 2 AVEQDMLIAVGPV--KTQTLQLANTDPLYPDFSTtanNICIDKTQPL-WHNYFLCGFKGIQEHFGLTQLpGMNCLVDGNI 78
Cdd:TIGR00131 44 AIDFGTLCAVAVRddKNVRIYLANADNKFAERSL---DLPLDGSEVSdWANYFKGVLHVAQERFNSFPL-GADIVCSGNV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 79 PPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELA-EICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKL 157
Cdd:TIGR00131 120 PTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILlRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKF 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 158 P-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKHKGLqwdkvlrleevqselgiSLEEMLLVTEDALHAepys 236
Cdd:TIGR00131 200 PqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAATDKG-----------------ALRDFMNEYFARYIA---- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 237 reeickclgisleelRTQILSPNTQgeltfklyQRAKHVYSEAARVLQfkqVCEAAPDNAVQLLGELMNQSHRSCRDMYE 316
Cdd:TIGR00131 258 ---------------RLTKMLPLVE--------ERAKHVVSENLRVLK---AVKAMKDNDFKQFGALMNESHASCDDDYE 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 564342729 317 CSCPELDQLVDICR-KFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAY 368
Cdd:TIGR00131 312 CTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKY 364
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
290-370 |
1.53e-09 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 54.40 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 290 EAAPDNAVQLLGELMNQSHRSC--RDMYECSCPELDQLVDICRKFGaKGSRLTGAGWGGCTVSLVP-ADTLSSFLASVHE 366
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG-LGAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 564342729 367 AYYQ 370
Cdd:pfam08544 82 AGKK 85
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-395 |
4.22e-134 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 393.30 E-value: 4.22e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 1 MAVEQDMLIAVGPVKTQT-LQLANTDPLYP--DFSTTANNiCIDKTQPLWHNYFLCGFKGIQEHFG-----LTQLPGMNC 72
Cdd:PLN02521 74 MAIRQDTIVAIRRAEGSKkLRIANVNDKYTtcTFPADPDQ-EVDLANHKWGNYFICGYKGVFEFLKskgvdVGPPVGLDV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 73 LVDGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRA 152
Cdd:PLN02521 153 VVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVAQFTCKCERHIGTQSGGMDQAISIMAQQGVAKLIDFNPVRA 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 153 TDVKLPSGAVFVIANSCVEMNKAATSH--FNVRVMECRLAAKVLAKHKGLQWD----KVLRLEEVQSeLGISLEE----- 221
Cdd:PLN02521 233 TDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAVKLGMSAEeaisKVKTLSDVEG-LCVSFAGshgss 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 222 -MLLVTEDALHAEPYSREEICKCLGISLEELRTQilSPNTQGELT----FKLYQRAKHVYSEAARVLQFKQVCEAAPDNA 296
Cdd:PLN02521 312 dPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRAVHVYSEAKRVHAFRDTVSSSLSEE 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 297 VQL--LGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQgnmS 374
Cdd:PLN02521 390 EKLkkLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVALVKEAIVPQFILALKEKFYK---S 466
|
410 420
....*....|....*....|....*...
gi 564342729 375 RLAREKHS-------LFATKPGGGALVF 395
Cdd:PLN02521 467 RIEKGVIKeedlglyVFASKPSSGAAIL 494
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-392 |
4.69e-66 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 214.63 E-value: 4.69e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 1 MAVEQDMLIAVGPVKTQTLQLANTDplYPD-FSTTANNICIDKTQPlWHNYFLCGFKGIQEHfGLtQLPGMNCLVDGNIP 79
Cdd:COG0153 44 AAIDRGTYAAARPRDDRKVRVYSAD--FDEeVEFDLDDLEPGEEDG-WANYVRGVAWALQER-GY-KLGGFDLVIDGDVP 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 80 PSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSE-RYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLP 158
Cdd:COG0153 119 LGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAEnEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLP 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 159 -SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKhkglqwdKVLRleEVqselgiSLEEmllvtedalhaepysr 237
Cdd:COG0153 199 lEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR--DV------TLED---------------- 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 238 eeickclgisLEELRTQILSPntqgeltfKLYQRAKHVYSEAARVLQFkqvCEAAPDNAVQLLGELMNQSHRSCRDMYEC 317
Cdd:COG0153 247 ----------LEAARARLGDE--------VLRRRARHVVTENQRVLEA---VEALRAGDLEAFGKLMNASHASLRDDYEV 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564342729 318 SCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQGnmsrlAREKHSLFATKPGGGA 392
Cdd:COG0153 306 SCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEK-----TGLEPDFYVVKPSDGA 376
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
2-368 |
2.40e-57 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 192.35 E-value: 2.40e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 2 AVEQDMLIAVGPV--KTQTLQLANTDPLYPDFSTtanNICIDKTQPL-WHNYFLCGFKGIQEHFGLTQLpGMNCLVDGNI 78
Cdd:TIGR00131 44 AIDFGTLCAVAVRddKNVRIYLANADNKFAERSL---DLPLDGSEVSdWANYFKGVLHVAQERFNSFPL-GADIVCSGNV 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 79 PPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELA-EICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKL 157
Cdd:TIGR00131 120 PTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILlRIQVAENHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKF 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 158 P-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKHKGLqwdkvlrleevqselgiSLEEMLLVTEDALHAepys 236
Cdd:TIGR00131 200 PqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAATDKG-----------------ALRDFMNEYFARYIA---- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 237 reeickclgisleelRTQILSPNTQgeltfklyQRAKHVYSEAARVLQfkqVCEAAPDNAVQLLGELMNQSHRSCRDMYE 316
Cdd:TIGR00131 258 ---------------RLTKMLPLVE--------ERAKHVVSENLRVLK---AVKAMKDNDFKQFGALMNESHASCDDDYE 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 564342729 317 CSCPELDQLVDICR-KFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAY 368
Cdd:TIGR00131 312 CTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKY 364
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
47-368 |
2.14e-33 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 128.44 E-value: 2.14e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 47 WHNYFLCGFKGIQEHfGLTQLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSE-RYIGTE 125
Cdd:PRK05322 91 WANYPKGVLKFLQEA-GYKIDHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQKTEnEFIGVN 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 126 GGGMDQSISFLAEEGTAKLI-------EFSPLRATDVKLpsgavfVIANScvemNKA---ATSHFNVRVMECRLAakvla 195
Cdd:PRK05322 170 SGIMDQFAIGMGKKDHAILLdcntleyEYVPLDLGDYVI------VIMNT----NKRrelADSKYNERRAECEKA----- 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 196 khkglqwdkvlrLEEVQSELGI-SLEEmllVTEDALhaepysreeickclgislEELRTQILSPNtqgeltfkLYQRAKH 274
Cdd:PRK05322 235 ------------LEELQKKLDIkSLGE---LTEEEF------------------DEYSYLIKDET--------LLKRARH 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 275 VYSEAARVLQFKqvcEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVP 353
Cdd:PRK05322 274 AVTENQRTLKAV---KALKAGDLEKFGRLMNASHVSLRDDYEVTGLELDTLVEAAWKQeGVLGARMTGAGFGGCAIAIVK 350
|
330
....*....|....*
gi 564342729 354 ADTLSSFLASVHEAY 368
Cdd:PRK05322 351 KDKVEAFKENVGKAY 365
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
38-370 |
9.49e-32 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 123.88 E-value: 9.49e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 38 ICIDKTQpLWHNYFLCGFKGIQEHfgLTQLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAK 117
Cdd:PRK05101 84 IVPHPEQ-QWANYVRGVVKHLQER--NPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 118 SE-RYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAK 196
Cdd:PRK05101 161 AEnQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPMPEGVAVVIINSNVKRG-LVDSEYNTRRQQCETAARFFGV 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 197 hkglqwdKVLRleevqselgisleemllvtedalhaepysreeickclGISLEELRTQilspntQGELTFKLYQRAKHVY 276
Cdd:PRK05101 240 -------KALR-------------------------------------DVTLEQFNAV------AAELDPVVAKRARHVI 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 277 SEAARVLQFKQVCEAapdNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICR-KFGAKGS-RLTGAGWGGCTVSLVPA 354
Cdd:PRK05101 270 TENARTLEAASALAA---GDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKaVIGDQGGvRMTGGGFGGCIVALVPE 346
|
330
....*....|....*.
gi 564342729 355 DTLSSFLASVHEAYYQ 370
Cdd:PRK05101 347 ELVEAVRQAVAEQYEA 362
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
69-369 |
9.04e-29 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 115.09 E-value: 9.04e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 69 GMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGMRLSKVELAEICAKSER-YIGTEGGGMDQSISFLAEEGTAKLIEF 147
Cdd:PRK03817 86 GVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENeFVGVPCGIMDQFAVAFGKKDHAIFLDT 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 148 SPLRATDVKLPSGAVFVIANSCVEmNKAATSHFNVRVMECRLAAKVLAKHkglqwdkvlrleevqselgiSLEEmllVTE 227
Cdd:PRK03817 166 MTLEYEYVPFPEDYEILVFDTGVK-RELASSEYNERRQECEEALKILGKK--------------------SSKE---VTE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 228 DALHaepysreeickclgiSLEELrtqilspntqgeltfkLYQRAKHVYSEAARVLQFKQvceAAPDNAVQLLGELMNQS 307
Cdd:PRK03817 222 EDLS---------------KLPPL----------------LRKRAGYVLRENERVLKVRD---ALKEGDIETLGELLTES 267
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564342729 308 HRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYY 369
Cdd:PRK03817 268 HWDLADNYEVSCEELDFFVEFALELGAYGARLTGAGFGGSAIALVDKGKFESIGEELLEEYK 329
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
89-392 |
6.52e-24 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 101.86 E-value: 6.52e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 89 ALVCCAGLVTLTVL-GMRLSKVELAEICAKSER-YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGA--VFV 164
Cdd:PRK00555 110 AALECAVLGAVGAAtGTRIDRLEQARLAQRAENeYVGAPTGLLDQLAALFGAPKTALLIDFRDLTVRPVAFDPDAagVVL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 165 IANSCVEMNKAATSHFNVRVMECRLAAKVLAkhkglqwdkVLRLEEVQsELGISleeMLLVTEDALHAepysreeickcl 244
Cdd:PRK00555 190 LLMDSRARHRHAGGEYAARRASCERAAADLG---------VSSLRAVQ-DRGLA---ALGAIADPIDA------------ 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 245 gisleelrtqilspntqgeltfklyQRAKHVYSEAARVLQFkqvCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQ 324
Cdd:PRK00555 245 -------------------------RRARHVLTENQRVLDF---AAALADSDFTAAGQLLTASHASMRDDFEITTERIDL 296
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564342729 325 LVDICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQGNMSRlarekHSLFATKPGGGA 392
Cdd:PRK00555 297 IADSAVRAGALGARMTGGGFGGCVIALVPADRAEDVADTVRRAAVTAGYPE-----PAVSRTYAAPGA 359
|
|
| PLN02865 |
PLN02865 |
galactokinase |
121-394 |
8.32e-16 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 78.69 E-value: 8.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 121 YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAV-------FVIANSCVEMNKAATSHFNVRVMECRLAAKV 193
Cdd:PLN02865 184 YLGLRNGILDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQQPggekpfkILLAFSGLRHALTNKPGYNLRVSECQEAARF 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 194 LAKHKGLqwdkvlrlEEVQSELGisleemllvtedALHAEPYSREeicKClgisleelrtqILSPNtqgeltfkLYQRAK 273
Cdd:PLN02865 264 LLEASGN--------DELEPLLC------------NVEPEVYEAH---KC-----------KLEAV--------LARRAE 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 274 HVYSEAARVLQFKqvcEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLV 352
Cdd:PLN02865 302 HYFSENMRVIKGV---EAWASGNLEEFGKLISASGLSSIENYECGCEPLIQLYEILLKApGVYGARFSGAGFRGCCVAFV 378
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 564342729 353 PADTLSSFLASVHEAYY--QGNMSRLAREKHSLFATKPGGGALV 394
Cdd:PLN02865 379 DAEMAEEAASFVRDEYEkaQPELASNINGDKPVLICEAGDCARV 422
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
105-394 |
1.17e-13 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 72.16 E-value: 1.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 105 RLSKVELAEIcAKSERYIGTEGGG-----MDQSISFLAEEG----------TAKLIEFSPLratdvkLPSGAVFVIANSC 169
Cdd:PTZ00290 187 PMSKEELIEL-AKQARRIETEFCGvnvgiMDQFISAFAEEDkfmfldckslTFESHDMTPL------LGDGACFLLIDSM 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 170 V--EMNKAATSHFNVRVMECRLAAKVLAKHKglqwdkvLRLEEVQSELGISLEEMLLVTEDALHAepysreeickclgis 247
Cdd:PTZ00290 260 IkhDLLGGTAGMYNTVRSDQEGAQKKIGKHR-------YRGKPFTFSDLVRNPKKYTFDGDVVAF--------------- 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 248 LEELRTQIlspnTQGEltfklYQRAKHVYSEAARVLQFKQVCEAA----PDNAVQLLGELMNQSHRSCRDMYECSCPELD 323
Cdd:PTZ00290 318 MESCKPLM----TPGE-----FERGTYNIMEQIRTLEFIKLNDPElplsREERFRKAGEILNAGHQGMRDLMKITTPELD 388
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564342729 324 QLVD-ICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYyqgnMSRLAREkHSLFATKPGGGALV 394
Cdd:PTZ00290 389 FIHElINEEKGVAGGRMMGGGFGGCIILLLKKNAVDRVVAHVREKF----KARFGVE-NDVYPVVAGDGAFV 455
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
267-351 |
9.71e-12 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 65.64 E-value: 9.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 267 KLYQRAKHVYSEAARVLQfkqvceaapDNAVQLLGELMNQSHRSCRDMyECSCPELDQLVDICRKFGAKGSRLTGAGWGG 346
Cdd:PTZ00298 218 RLLENYNACVSEAKEALQ---------KGNLFRVGELMNANHDLCQKL-TVSCRELDSIVQTCRTYGALGAKMSGTGRGG 287
|
....*
gi 564342729 347 CTVSL 351
Cdd:PTZ00298 288 LVVAL 292
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
262-351 |
1.19e-10 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 61.54 E-value: 1.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 262 GELTFKLYQRAKHVYSEAARVLQfkqvceaapDNAVQLLGELMNQSHrSCRDMYECSCPELDQLVDICRKFGAKGSRLTG 341
Cdd:TIGR00549 194 PELIDSIMDAIGELTLEAKAALQ---------DGDVESLGELMNINQ-GLLKALGVSHPKLDQLVEIARKAGALGAKLTG 263
|
90
....*....|
gi 564342729 342 AGWGGCTVSL 351
Cdd:TIGR00549 264 AGGGGCMIAL 273
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
102-352 |
1.22e-10 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 61.78 E-value: 1.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 102 LGMRLSKVELAEICAKSERYIGTEGGGMDQSISFLaeEGtakLIEF-SPLRATDVKLPSGAVFVIANSCVemnKAATSHf 180
Cdd:COG1577 114 YGVELSKEELFKLALEAEKIVHGNPSGLDTAASTY--GG---PIYYqRGDRAEPLELPKNLPLVVGDTGV---PASTKE- 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 181 nvrvmecrLAAKVLAKHKglqwdkvlRLEEVQSELgisLEEMLLVTEDALHAepysreeickclgisLEElrtqilspnt 260
Cdd:COG1577 185 --------LVAKVRKLKE--------RNPELYEAF---LEEIGDLVEEAIEA---------------LEE---------- 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 261 qgeltfklyqrakhvyseaarvlqfkqvceaapdNAVQLLGELMNQSHRSCRDMYeCSCPELDQLVDICRKFGAKGSRLT 340
Cdd:COG1577 221 ----------------------------------GDLEALGELMNENHGLLRALG-VSTPELDRLVEAARKAGALGAKLT 265
|
250
....*....|..
gi 564342729 341 GAGWGGCTVSLV 352
Cdd:COG1577 266 GAGGGGCVIALA 277
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
290-370 |
1.53e-09 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 54.40 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 290 EAAPDNAVQLLGELMNQSHRSC--RDMYECSCPELDQLVDICRKFGaKGSRLTGAGWGGCTVSLVP-ADTLSSFLASVHE 366
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG-LGAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 564342729 367 AYYQ 370
Cdd:pfam08544 82 AGKK 85
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
300-355 |
2.23e-08 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 55.06 E-value: 2.23e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 564342729 300 LGELMNQSHrSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPAD 355
Cdd:PRK03926 216 LGELMNINQ-GLLDALGVSTKELSELIYAARTAGALGAKITGAGGGGCMVALAAPE 270
|
|
| COG2605 |
COG2605 |
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ... |
270-355 |
1.12e-03 |
|
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain] Cd Length: 328 Bit Score: 40.55 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342729 270 QRAKHVYSEAARVLQFKQVCEAAPD--NAVQ-----LLGELMNQSHRSCRDMYE-CSCPELDQLVDICRKFGAKGSRLTG 341
Cdd:COG2605 205 QVKNVEDGDEATLEALHEMKELALEmkEALLkgdldEFGELLNEGWELKKRLASgISNPAIDEIYELARKAGALGGKLLG 284
|
90
....*....|....
gi 564342729 342 AGWGGCTVSLVPAD 355
Cdd:COG2605 285 AGGGGFLLFYAPPE 298
|
|
| |
