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Conserved domains on  [gi|564380391|ref|XP_006249779|]
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complement decay-accelerating factor isoform X2 [Rattus norvegicus]

Protein Classification

CCP domain-containing protein( domain architecture ID 12867676)

CCP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 94-283 1.01e-32

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.15  E-value: 1.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  94 CNKTCSAPLRLNYASLKKEYRNMNFfPIGTTVEFECRPGFQKVTSRTGKSTCLEElVWSpVVEFCKKRACPNPRELKNGH 173
Cdd:PHA02927  20 CCTIPSRPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWT-LFNQCIKRRCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 174 INIpTDILFGSEIIFSCDKGYKLVGVTSTFCSI--TGNAVdWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTY 251
Cdd:PHA02927  97 LDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTY 174

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564380391 252 SCDQGFILVGNSSVHCTlngeVGEWSSaPPKC 283
Cdd:PHA02927 175 SCNSGYSLIGNSGVLCS----GGEWSD-PPTC 201
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 7.88e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 7.88e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  36 CGPPPDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIPdkPNTVVCLENDQWSNYETFC 94
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 94-283 1.01e-32

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.15  E-value: 1.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  94 CNKTCSAPLRLNYASLKKEYRNMNFfPIGTTVEFECRPGFQKVTSRTGKSTCLEElVWSpVVEFCKKRACPNPRELKNGH 173
Cdd:PHA02927  20 CCTIPSRPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWT-LFNQCIKRRCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 174 INIpTDILFGSEIIFSCDKGYKLVGVTSTFCSI--TGNAVdWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTY 251
Cdd:PHA02927  97 LDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTY 174

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564380391 252 SCDQGFILVGNSSVHCTlngeVGEWSSaPPKC 283
Cdd:PHA02927 175 SCNSGYSLIGNSGVLCS----GGEWSD-PPTC 201
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 1.14e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 70.95  E-value: 1.14e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKCI 284
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 8.86e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 65.63  E-value: 8.86e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391   225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN---GTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 1.52e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 64.83  E-value: 1.52e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED---GTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 7.88e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 7.88e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  36 CGPPPDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIPdkPNTVVCLENDQWSNYETFC 94
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 9.28e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 9.28e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391    36 CGPPPDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIPdkPNTVVCLENDQWSNYETFC 94
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
36-94 5.57e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 5.57e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391   36 CGPPPDIPNAtPNSGKHTKFAHQSQVTYSCNKGFKqiPDKPNTVVCLENDQWSNYETFC 94
Cdd:pfam00084   1 CPPPPDIPNG-KVSATKNEYNYGASVSYECDPGYR--LVGSPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 94-283 1.01e-32

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 125.15  E-value: 1.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  94 CNKTCSAPLRLNYASLKKEYRNMNFfPIGTTVEFECRPGFQKVTSRTGKSTCLEElVWSpVVEFCKKRACPNPRELKNGH 173
Cdd:PHA02927  20 CCTIPSRPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWT-LFNQCIKRRCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 174 INIpTDILFGSEIIFSCDKGYKLVGVTSTFCSI--TGNAVdWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTY 251
Cdd:PHA02927  97 LDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTY 174

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564380391 252 SCDQGFILVGNSSVHCTlngeVGEWSSaPPKC 283
Cdd:PHA02927 175 SCNSGYSLIGNSGVLCS----GGEWSD-PPTC 201
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 225-284 1.14e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 70.95  E-value: 1.14e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKCI 284
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN---GGWSPPPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 36-284 7.49e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.61  E-value: 7.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  36 CGPPPDIPNATPNSGKhTKFAhqSQVTYSCNKGFKQIpdkpntvvclendqwSNYETFCNktcsaplrlnyaslkkeyrn 115
Cdd:PHA02927  86 CPSPRDIDNGQLDIGG-VDFG--SSITYSCNSGYQLI---------------GESKSYCE-------------------- 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 116 mnffpIGTTvefecrpgfqkvtsrtgkstclEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILF-GSEIIFSCDKGY 194
Cdd:PHA02927 128 -----LGST----------------------GSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdGSVVTYSCNSGY 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 195 KLVGVTSTFCSitgnAVDWDDVfPVCTTIFCPDpPKINNGRIREE-SDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgev 273
Cdd:PHA02927 181 SLIGNSGVLCS----GGEWSDP-PTCQIVKCPH-PTISNGYLSSGfKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPG--- 251

                        250
                 ....*....|.
gi 564380391 274 GEWSSAPPKCI 284
Cdd:PHA02927 252 NTWQPELPKCV 262
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 225-283 8.86e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 65.63  E-value: 8.86e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391   225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKC 283
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN---GTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
225-283 1.52e-13

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 64.83  E-value: 1.52e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  225 CPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKC 283
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED---GTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 40-288 4.27e-11

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 63.95  E-value: 4.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  40 PDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIpdKPNTVVclENDQWsNYETFCNKTCSAPlrlNYASlkkEYRNMNFF 119
Cdd:PHA02954  24 PTMNNAKLTSTE-TSFNDKQKVTFTCDSGYYSL--DPNAVC--ETDKW-KYENPCKKMCTVS---DYVS---ELYDKPLY 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 120 PIGTTVEFECR--PGFQKVTSRTGKSTcleelvWSPVVefckkrACPN----PRELKNGHIN-IPTDILFGSEIIFSCDK 192
Cdd:PHA02954  92 EVNSTITLICKdeTKYFRCEEKNGNTS------WNDTV------TCPNaecqPLQLEHGSCQpVKEKYSFGEHITINCDV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 193 GYKLVGVTSTFCSitgnAVDWdDVFPVCTTIFcpDPPKINNGRIreESDSYAYRQSVTYSCDQGFILVGNSSVHCTlnge 272
Cdd:PHA02954 160 GYEVIGASYISCT----ANSW-NVIPSCQQKC--DIPSLSNGLI--SGSTFSIGGVIHLSCKSGFTLTGSPSSTCI---- 226

                        250
                 ....*....|....*.
gi 564380391 273 VGEWSSAPPKCIERHK 288
Cdd:PHA02954 227 DGKWNPVLPICVRSNE 242
PHA02639 PHA02639
EEV host range protein; Provisional
 116-289 4.37e-11

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 63.53  E-value: 4.37e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 116 MNFFPIGTTVEFECRPGFQKVTSRTgkSTCLEE---LVWSPVVEFCKKRACPNPRELKNGHINIPTDIL-FGSEIIFSCD 191
Cdd:PHA02639  37 MEKYEIGKLIEYTCNTDYALIGDRF--RTCIKDknnAIWSNKAPFCMLKECNDPPSIINGKIYNKREMYkVGDEIYYVCN 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 192 --KG--YKLVGVTSTFCSitgNAVDWDDVFPVCTTIFCpDPPKINNGRIR--EESDSYAYRQSVTYSCDQGFILVGNSSV 265
Cdd:PHA02639 115 ehKGvqYSLVGNEKITCI---QDKSWKPDPPICKMINC-RFPALQNGYINgiPSNKKFYYKTRVGFSCKSGFDLVGEKYS 190

                        170       180
                 ....*....|....*....|....
gi 564380391 266 HCTLNgevGEWSSAPPKCIERHKV 289
Cdd:PHA02639 191 TCNIN---ATWFPSIPTCVRNKPI 211
PHA02639 PHA02639
EEV host range protein; Provisional
 159-283 3.75e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 60.83  E-value: 3.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 159 KKRACPNPRELKNGHIN-IPTDILFGSEIIFSCDKGYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIR 237
Cdd:PHA02639  18 KSIYCDKPDDISNGFITeLMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 564380391 238 EESDSYAYRQSVTYSCDQ----GFILVGNSSVHCTLNgevGEWSSAPPKC 283
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQD---KSWKPDPPIC 144
PHA02817 PHA02817
EEV Host range protein; Provisional
 154-288 5.62e-10

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 59.18  E-value: 5.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 154 VVEFCKKRACPNPRELKNGHI-NIPTDILFGSEIIFSCDKG-----YKLVGVTSTFCSITGNavdWDDVFPVCTTIFCpD 227
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIyNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKIIRC-R 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564380391 228 PPKINNGRIR--EESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWSSAPPKCIERHK 288
Cdd:PHA02817  91 FPALQNGFVNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGIN---SSWIPKVPICSRDNI 150
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 36-94 7.88e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 7.88e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  36 CGPPPDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIPdkPNTVVCLENDQWSNYETFC 94
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 125-285 1.20e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 58.85  E-value: 1.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 125 VEFECRPGFQKV--TSRTGKstcleelvWSPVVEFCKKRACPNPRELKNGHINIPTDIL-FGSEIIFSCD----KGYKLV 197
Cdd:PHA02831  46 LEYKCNNNFDKVfvTCNNGS--------WSTKNMCIGKRNCKDPVTILNGYIKNKKDQYsFGDSVTYACKvnklEKYSIV 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391 198 GVTSTFCsITGNavdWDDVFPVCTTIFCpDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNgevGEWS 277
Cdd:PHA02831 118 GNETVKC-INKQ---WVPKYPVCKLIRC-KYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDIN---SIWY 189


                 ....*...
gi 564380391 278 SAPPKCIE 285
Cdd:PHA02831 190 PGIPKCVK 197
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 36-94 9.28e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 9.28e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391    36 CGPPPDIPNATPNSGKhTKFAHQSQVTYSCNKGFKQIPdkPNTVVCLENDQWSNYETFC 94
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 163-220 3.28e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.77  E-value: 3.28e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391 163 CPNPRELKNGHINIPTDI-LFGSEIIFSCDKGYKLVGVTSTFCSITGNavdWDDVFPVC 220
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
36-94 5.57e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.03  E-value: 5.57e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391   36 CGPPPDIPNAtPNSGKHTKFAHQSQVTYSCNKGFKqiPDKPNTVVCLENDQWSNYETFC 94
Cdd:pfam00084   1 CPPPPDIPNG-KVSATKNEYNYGASVSYECDPGYR--LVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 163-220 5.85e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.06  E-value: 5.85e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391   163 CPNPRELKNGHIN-IPTDILFGSEIIFSCDKGYKLVGVTSTFCSITGNavdWDDVFPVC 220
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
98-158 7.33e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.95  E-value: 7.33e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564380391   98 CSAPLRLNYASLkkeYRNMNFFPIGTTVEFECRPGFQKVTSRTgkSTCLEELVWSPVVEFC 158
Cdd:pfam00084   1 CPPPPDIPNGKV---SATKNEYNYGASVSYECDPGYRLVGSPT--ITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
163-220 3.74e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.03  E-value: 3.74e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564380391  163 CPNPRELKNGHINIPTDI-LFGSEIIFSCDKGYKLVGVTSTFCSITGNavdWDDVFPVC 220
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEyNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 98-159 4.38e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 4.38e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564380391  98 CSAPLRLNYASLKKEyrnMNFFPIGTTVEFECRPGFQKVTSRTgkSTCLEELVWSPVVEFCK 159
Cdd:cd00033    1 CPPPPVPENGTVTGS---KGSYSYGSTVTYSCNEGYTLVGSST--ITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 98-158 4.45e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.97  E-value: 4.45e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564380391    98 CSAPLRLNYASLKKEYRNmnfFPIGTTVEFECRPGFQKVTSRTgkSTCLEELVWSPVVEFC 158
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGSST--ITCLENGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 225-290 8.91e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 44.21  E-value: 8.91e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564380391 225 CPDPPKINNGRIREESDSYAYRQSVTYSCD----QGFILVGNSSVHCTlngeVGEWSSAPPKC-IERHKVP 290
Cdd:PHA02831  78 CKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVGNETVKCI----NKQWVPKYPVCkLIRCKYP 144
PHA02639 PHA02639
EEV host range protein; Provisional
 222-297 3.67e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 39.26  E-value: 3.67e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564380391 222 TIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNGEVGEWSSAPPKCIERHkvpTKTPPEV 297
Cdd:PHA02639  19 SIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKE---CNDPPSI 91
PHA02831 PHA02831
EEV host range protein; Provisional
 35-160 4.36e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 38.82  E-value: 4.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564380391  35 DCGPPPDIPNATPNSgKHTKFAHQSQVTYSC--NKGFKQIPDKPNTVVCLeNDQWSNYETFCNKtcsapLRLNYASLKKE 112
Cdd:PHA02831  77 NCKDPVTILNGYIKN-KKDQYSFGDSVTYACkvNKLEKYSIVGNETVKCI-NKQWVPKYPVCKL-----IRCKYPALQNG 149

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 564380391 113 YRNM--NFFPIGTTVEFECRPGFQKVTSRTgkSTCLEELVWSPVVEFCKK 160
Cdd:PHA02831 150 FLNVfeKKFYYGDIVNFKCKKGFILLGSSV--STCDINSIWYPGIPKCVK 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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