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Conserved domains on  [gi|568918149|ref|XP_006500122|]
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protein FAM210B, mitochondrial isoform X1 [Mus musculus]

Protein Classification

FAM210 family protein( domain architecture ID 10536487)

FAM210 family protein is a DUF1279 domain-containing protein; similar to Homo sapiens mitochondrial protein FAM210B that is involved in cell proliferation and tumor cell growth suppression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-172 7.41e-37

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


:

Pssm-ID: 429191  Cd Length: 88  Bit Score: 123.14  E-value: 7.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918149   85 QQLKKVFQEYGAVGVSMHIGISLVSLGIFYTVVSSGIDMSAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRIS 164
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 568918149  165 ITLVSVPF 172
Cdd:pfam06916  81 ITLALTPL 88
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-172 7.41e-37

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 123.14  E-value: 7.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918149   85 QQLKKVFQEYGAVGVSMHIGISLVSLGIFYTVVSSGIDMSAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRIS 164
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 568918149  165 ITLVSVPF 172
Cdd:pfam06916  81 ITLALTPL 88
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-172 7.41e-37

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 123.14  E-value: 7.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568918149   85 QQLKKVFQEYGAVGVSMHIGISLVSLGIFYTVVSSGIDMSAILLKLGFKESLVQSKMAAGTSTFVVAYAIHKLFAPVRIS 164
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSSGVDVIALLEKLGISDNKVESLSASGWGTFAIAYAIHKIAAPIRLP 80


                  ....*...
gi 568918149  165 ITLVSVPF 172
Cdd:pfam06916  81 ITLALTPL 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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