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Conserved domains on  [gi|568963928|ref|XP_006512224|]
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TPR and ankyrin repeat-containing protein 1 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HelD super family cl28314
DNA helicase IV [Replication, recombination and repair];
1476-1672 3.25e-11

DNA helicase IV [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG3973:

Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1476 DEIQDFTQAELALLMKCIndPNAMF-LTGDTAQSImkgvaFRFSDLlslfhyASRSTVDKQCaVRKPKRIHQLYQNYRSH 1554
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGA------ESWEEVLEPL-GGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1555 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTLLDSCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1624
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568963928 1625 -----LVANEKAKEKIPEELGLA---LVLTVYEAKGLEFDDVLLYNFftDSEAYKE 1672
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
528-684 2.31e-09

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 61.51  E-value: 2.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  528 TQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLH-AALHIFLDInadigfnfls 606
Cdd:COG0666   100 LEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHlAAANGNLEI---------- 168

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568963928  607 hlLDLFLSNPTefyylNPNVQDSNGNTLMHLLFQKGmlkrTKKLIDLLVKFDINFNLKNKAGKGVRHRIKKNDALLLA 684
Cdd:COG0666   169 --VKLLLEAGA-----DVNARDNDGETPLHLAAENG----HLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR super family cl34000
Ankyrin repeat [Signal transduction mechanisms];
321-446 5.88e-08

Ankyrin repeat [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG0666:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 57.27  E-value: 5.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDQKPEwkehINHRDDAGCTVLHVAAAHfpgytsrRQTE 400
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLH-LAAANGNLEIVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GHLE 200

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568963928  401 DVQMLLSFGADPTLLDGHARTVVDVLKRNKNFRAIDKINSHLEKLA 446
Cdd:COG0666   201 IVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN 246
PHA03381 super family cl31824
tegument protein VP22; Provisional
 22-136 4.39e-07

tegument protein VP22; Provisional


The actual alignment was detected with superfamily member PHA03381:

Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 54.25  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAKLSAPEAGPPR--RGPLPRGGAGRDTllgakatpSSPAARRYVTALGPPQPRGSTdSACAAlpqpvphepr 99
Cdd:PHA03381   87 PRPSRRPHAQPEASGPGPARgaRGPAGSRGRGRRA--------ESPSPRDPPNPKGASAPRGRK-SACAD---------- 147

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 568963928  100 EAAFRLAPASER-GASVSPARIPRRR--RRVP----AMWDPRAA 136
Cdd:PHA03381  148 SAALLDAPAPAApKRQKTPAGLARKLhfSTAPtsptAPWTPRVA 191
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 134-217 1.07e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.60  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  134 RAARTPPrELAMLLCNKSNAFYNLGKWNEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFfegLRLLQRSPD 213
Cdd:COG3914   137 RALALNP-DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY---RRALELDPD 212


                  ....
gi 568963928  214 QLQV 217
Cdd:COG3914   213 NADA 216
UvrD_C super family cl37858
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
 205-340 1.30e-03

UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.


The actual alignment was detected with superfamily member pfam13361:

Pssm-ID: 433145 [Multi-domain]  Cd Length: 377  Bit Score: 43.93  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   205 LRLLQRSPdqLQVPDFLVGIFTTMSSIGM--SDPGGGDSIVL-QSFLPCFDH-------IFTTGFST---EVWQYVIQKL 271
Cdd:pfam13361  136 KRILNGPK--RGIGNATLERIREYKKRGLrlSDFINPDTLTYgDPFVIALEQdnivvfdVETTGLDTtedEIIQIAAIKL 213

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568963928   272 AKKG-LWHSFLLLSAKKDRLPSNIHVSELSLQSLFEKY-----VFIGFYEKLEQVPKLVQWLVSIGANIETIGPN 340
Cdd:pfam13361  214 NKKGvVIESFERFLRLKKPVGDSLQVHGFSDEFLQENGetpaeALRDFLEKLENLRELYSILREYDDIEETPEPE 288
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1987-2144 5.77e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1987 LAEAAELLNREGRREEAALLMKQHGCLLEAARLTANKDFQASCLLGVARFNVARDSdiehtkviLREALDLCYQTSQLA- 2065
Cdd:COG3914    38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--------YEEALALYRRALALNp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 2066 GIAEAQFLLGIILRDFQKLRDAFIKFDM-LNHSAGMVEALYEAASLCESEHQ---------KVLALAPGGLEVLLNLVRA 2135
Cdd:COG3914   110 DNAEALFNLGNLLLALGRLEEALAALRRaLALNPDFAEAYLNLGEALRRLGRleeaiaalrRALELDPDNAEALNNLGNA 189


                  ....*....
gi 568963928 2136 LKNVTNNAE 2144
Cdd:COG3914   190 LQDLGRLEE 198
 
Name Accession Description Interval E-value
HelD COG3973
DNA helicase IV [Replication, recombination and repair];
1476-1672 3.25e-11

DNA helicase IV [Replication, recombination and repair];


Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1476 DEIQDFTQAELALLMKCIndPNAMF-LTGDTAQSImkgvaFRFSDLlslfhyASRSTVDKQCaVRKPKRIHQLYQNYRSH 1554
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGA------ESWEEVLEPL-GGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1555 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTLLDSCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1624
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568963928 1625 -----LVANEKAKEKIPEELGLA---LVLTVYEAKGLEFDDVLLYNFftDSEAYKE 1672
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
528-684 2.31e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 61.51  E-value: 2.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  528 TQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLH-AALHIFLDInadigfnfls 606
Cdd:COG0666   100 LEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHlAAANGNLEI---------- 168

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568963928  607 hlLDLFLSNPTefyylNPNVQDSNGNTLMHLLFQKGmlkrTKKLIDLLVKFDINFNLKNKAGKGVRHRIKKNDALLLA 684
Cdd:COG0666   169 --VKLLLEAGA-----DVNARDNDGETPLHLAAENG----HLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
321-446 5.88e-08

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 57.27  E-value: 5.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDQKPEwkehINHRDDAGCTVLHVAAAHfpgytsrRQTE 400
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLH-LAAANGNLEIVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GHLE 200

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568963928  401 DVQMLLSFGADPTLLDGHARTVVDVLKRNKNFRAIDKINSHLEKLA 446
Cdd:COG0666   201 IVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN 246
PHA03381 PHA03381
tegument protein VP22; Provisional
 22-136 4.39e-07

tegument protein VP22; Provisional


Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 54.25  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAKLSAPEAGPPR--RGPLPRGGAGRDTllgakatpSSPAARRYVTALGPPQPRGSTdSACAAlpqpvphepr 99
Cdd:PHA03381   87 PRPSRRPHAQPEASGPGPARgaRGPAGSRGRGRRA--------ESPSPRDPPNPKGASAPRGRK-SACAD---------- 147

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 568963928  100 EAAFRLAPASER-GASVSPARIPRRR--RRVP----AMWDPRAA 136
Cdd:PHA03381  148 SAALLDAPAPAApKRQKTPAGLARKLhfSTAPtsptAPWTPRVA 191
DUF4813 pfam16072
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ...
 38-140 5.19e-06

Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.


Pssm-ID: 435117 [Multi-domain]  Cd Length: 288  Bit Score: 50.91  E-value: 5.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928    38 GPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYvtalgPPQPRGSTDSACAALPQPVPHEPREAAFRLAP--------AS 109
Cdd:pfam16072  144 GPPGSVTTTSAGSGTTVINAGGQQPAAPAAPAY-----PVAPAAYPAQAPAAAPAPAPGAPQTPLAPLNPvaaapaaaAG 218

                           90       100       110
                   ....*....|....*....|....*....|..
gi 568963928   110 ERGASVSPARIPRRRRRVP-AMWDPRAARTPP 140
Cdd:pfam16072  219 AAAAPVVAAAAPAAAAPPPpAPAAPPADAAPP 250
Ank_2 pfam12796
Ankyrin repeats (3 copies);
321-416 1.27e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 43.18  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDqkpewKEHINHRDDaGCTVLHVAAAHfpgytsrRQTE 400
Cdd:pfam12796   10 LELVKLLLENGADANLQDKNGRTALH-LAAKNGHLEIVKLLLE-----HADVNLKDN-GRTALHYAARS-------GHLE 75

                           90
                   ....*....|....*.
gi 568963928   401 DVQMLLSFGADPTLLD 416
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 316-431 3.61e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 45.79  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  316 KLEQVPKLVQWLVSIGANIETI---GPNPLHALMRLCIQAResqlfrwVMDQKPEWKEHINHRDDAGCTVLHVAAAHFpg 392
Cdd:PHA03095   58 SSEKVKDIVRLLLEAGADVNAPercGFTPLHLYLYNATTLD-------VIKLLIKAGADVNAKDKVGRTPLHVYLSGF-- 128

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 568963928  393 ytsRRQTEDVQMLLSFGADPTLLDGHARTVVDVLKRNKN 431
Cdd:PHA03095  129 ---NINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRN 164
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 134-217 1.07e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.60  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  134 RAARTPPrELAMLLCNKSNAFYNLGKWNEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFfegLRLLQRSPD 213
Cdd:COG3914   137 RALALNP-DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY---RRALELDPD 212


                  ....
gi 568963928  214 QLQV 217
Cdd:COG3914   213 NADA 216
UvrD_C pfam13361
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
 205-340 1.30e-03

UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.


Pssm-ID: 433145 [Multi-domain]  Cd Length: 377  Bit Score: 43.93  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   205 LRLLQRSPdqLQVPDFLVGIFTTMSSIGM--SDPGGGDSIVL-QSFLPCFDH-------IFTTGFST---EVWQYVIQKL 271
Cdd:pfam13361  136 KRILNGPK--RGIGNATLERIREYKKRGLrlSDFINPDTLTYgDPFVIALEQdnivvfdVETTGLDTtedEIIQIAAIKL 213

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568963928   272 AKKG-LWHSFLLLSAKKDRLPSNIHVSELSLQSLFEKY-----VFIGFYEKLEQVPKLVQWLVSIGANIETIGPN 340
Cdd:pfam13361  214 NKKGvVIESFERFLRLKKPVGDSLQVHGFSDEFLQENGetpaeALRDFLEKLENLRELYSILREYDDIEETPEPE 288
Ank_2 pfam12796
Ankyrin repeats (3 copies);
552-665 4.37e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.94  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   552 LLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLHAAlhifldinADIG-FNFLSHLLDlflsnptefyYLNPNVQDsN 630
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDK-NGRTALHLA--------AKNGhLEIVKLLLE----------HADVNLKD-N 60

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 568963928   631 GNTLMHLLFQKGMLkrtkKLIDLLVKFDINFNLKN 665
Cdd:pfam12796   61 GRTALHYAARSGHL----EIVKLLLEKGADINVKD 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1987-2144 5.77e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1987 LAEAAELLNREGRREEAALLMKQHGCLLEAARLTANKDFQASCLLGVARFNVARDSdiehtkviLREALDLCYQTSQLA- 2065
Cdd:COG3914    38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--------YEEALALYRRALALNp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 2066 GIAEAQFLLGIILRDFQKLRDAFIKFDM-LNHSAGMVEALYEAASLCESEHQ---------KVLALAPGGLEVLLNLVRA 2135
Cdd:COG3914   110 DNAEALFNLGNLLLALGRLEEALAALRRaLALNPDFAEAYLNLGEALRRLGRleeaiaalrRALELDPDNAEALNNLGNA 189


                  ....*....
gi 568963928 2136 LKNVTNNAE 2144
Cdd:COG3914   190 LQDLGRLEE 198
 
Name Accession Description Interval E-value
HelD COG3973
DNA helicase IV [Replication, recombination and repair];
1476-1672 3.25e-11

DNA helicase IV [Replication, recombination and repair];


Pssm-ID: 443173 [Multi-domain]  Cd Length: 699  Bit Score: 69.12  E-value: 3.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1476 DEIQDFTQAELALLMKCIndPNAMF-LTGDTAQSImkgvaFRFSDLlslfhyASRSTVDKQCaVRKPKRIHQLYQNYRSH 1554
Cdd:COG3973   476 DEAQDLSPMQWRVLKRRF--PSASFtIVGDLAQAI-----HPYRGA------ESWEEVLEPL-GGDRARLVELTKSYRST 541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1555 SGILNLASGVVDLLQF--YFPESFDRlprdsglfDGPKPTLLDSCSVSDLAILLRGNKRKTQPIEFGAHQVI-------- 1624
Cdd:COG3973   542 AEIMEFANRVLRAAGPdlPPPESVRR--------HGEPPRVVRVPSEAELAAAVVEAVRELLAEGEGTIAVIcktareae 613

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568963928 1625 -----LVANEKAKEKIPEELGLA---LVLTVYEAKGLEFDDVLLYNFftDSEAYKE 1672
Cdd:COG3973   614 alyaaLKAGLPVTLIDDESEELEagvVVLPAYLAKGLEFDAVVVVDP--DEIVYES 667
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
528-684 2.31e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 61.51  E-value: 2.31e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  528 TQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLH-AALHIFLDInadigfnfls 606
Cdd:COG0666   100 LEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDN-DGNTPLHlAAANGNLEI---------- 168

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568963928  607 hlLDLFLSNPTefyylNPNVQDSNGNTLMHLLFQKGmlkrTKKLIDLLVKFDINFNLKNKAGKGVRHRIKKNDALLLA 684
Cdd:COG0666   169 --VKLLLEAGA-----DVNARDNDGETPLHLAAENG----HLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIV 235
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
321-446 5.88e-08

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 57.27  E-value: 5.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDQKPEwkehINHRDDAGCTVLHVAAAHfpgytsrRQTE 400
Cdd:COG0666   133 LEIVKLLLEAGADVNAQDNDGNTPLH-LAAANGNLEIVKLLLEAGAD----VNARDNDGETPLHLAAEN-------GHLE 200

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568963928  401 DVQMLLSFGADPTLLDGHARTVVDVLKRNKNFRAIDKINSHLEKLA 446
Cdd:COG0666   201 IVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN 246
PHA03381 PHA03381
tegument protein VP22; Provisional
 22-136 4.39e-07

tegument protein VP22; Provisional


Pssm-ID: 177618 [Multi-domain]  Cd Length: 290  Bit Score: 54.25  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAKLSAPEAGPPR--RGPLPRGGAGRDTllgakatpSSPAARRYVTALGPPQPRGSTdSACAAlpqpvphepr 99
Cdd:PHA03381   87 PRPSRRPHAQPEASGPGPARgaRGPAGSRGRGRRA--------ESPSPRDPPNPKGASAPRGRK-SACAD---------- 147

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 568963928  100 EAAFRLAPASER-GASVSPARIPRRR--RRVP----AMWDPRAA 136
Cdd:PHA03381  148 SAALLDAPAPAApKRQKTPAGLARKLhfSTAPtsptAPWTPRVA 191
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
534-668 2.44e-06

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 52.26  E-value: 2.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  534 LIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLH-AALHIFLDInadigfnflshlLDLF 612
Cdd:COG0666    73 LLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDK-DGETPLHlAAYNGNLEI------------VKLL 139

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568963928  613 LSNPtefyyLNPNVQDSNGNTLMHLLFQKGMLkrtkKLIDLLVKFDINFNLKNKAG 668
Cdd:COG0666   140 LEAG-----ADVNAQDNDGNTPLHLAAANGNL----EIVKLLLEAGADVNARDNDG 186
DUF4813 pfam16072
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ...
 38-140 5.19e-06

Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.


Pssm-ID: 435117 [Multi-domain]  Cd Length: 288  Bit Score: 50.91  E-value: 5.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928    38 GPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYvtalgPPQPRGSTDSACAALPQPVPHEPREAAFRLAP--------AS 109
Cdd:pfam16072  144 GPPGSVTTTSAGSGTTVINAGGQQPAAPAAPAY-----PVAPAAYPAQAPAAAPAPAPGAPQTPLAPLNPvaaapaaaAG 218

                           90       100       110
                   ....*....|....*....|....*....|..
gi 568963928   110 ERGASVSPARIPRRRRRVP-AMWDPRAARTPP 140
Cdd:pfam16072  219 AAAAPVVAAAAPAAAAPPPpAPAAPPADAAPP 250
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
321-421 6.10e-05

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 47.64  E-value: 6.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDQKPEwkehINHRDDAGCTVLHVAAAHfpgytsrRQTE 400
Cdd:COG0666   100 LEIVKLLLEAGADVNARDKDGETPLH-LAAYNGNLEIVKLLLEAGAD----VNAQDNDGNTPLHLAAAN-------GNLE 167

                          90       100
                  ....*....|....*....|.
gi 568963928  401 DVQMLLSFGADPTLLDGHART 421
Cdd:COG0666   168 IVKLLLEAGADVNARDNDGET 188
Ank_2 pfam12796
Ankyrin repeats (3 copies);
321-416 1.27e-04

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 43.18  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   321 PKLVQWLVSIGANIETIGPNPLHALMrLCIQARESQLFRWVMDqkpewKEHINHRDDaGCTVLHVAAAHfpgytsrRQTE 400
Cdd:pfam12796   10 LELVKLLLENGADANLQDKNGRTALH-LAAKNGHLEIVKLLLE-----HADVNLKDN-GRTALHYAARS-------GHLE 75

                           90
                   ....*....|....*.
gi 568963928   401 DVQMLLSFGADPTLLD 416
Cdd:pfam12796   76 IVKLLLEKGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 316-431 3.61e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 45.79  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  316 KLEQVPKLVQWLVSIGANIETI---GPNPLHALMRLCIQAResqlfrwVMDQKPEWKEHINHRDDAGCTVLHVAAAHFpg 392
Cdd:PHA03095   58 SSEKVKDIVRLLLEAGADVNAPercGFTPLHLYLYNATTLD-------VIKLLIKAGADVNAKDKVGRTPLHVYLSGF-- 128

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 568963928  393 ytsRRQTEDVQMLLSFGADPTLLDGHARTVVDVLKRNKN 431
Cdd:PHA03095  129 ---NINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRN 164
PHA03247 PHA03247
large tegument protein UL36; Provisional
 23-146 5.21e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAP--GAKLSAPEAGP-PRRGPLPRGGAGrDTLLGAKATPSSPAArryvTALGPPQPRGSTDSACAALPQPVPHEPR 99
Cdd:PHA03247 2575 PRPSEPavTSRARRPDAPPqSARPRAPVDDRG-DPRGPAPPSPLPPDT----HAPDPPPPSPSPAANEPDPHPPPTVPPP 2649

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568963928  100 EAAfRLAPASERgasVSPAR------IPRRRRRVPAMWDPRAARTPPRELAML 146
Cdd:PHA03247 2650 ERP-RDDPAPGR---VSRPRrarrlgRAAQASSPPQRPRRRAARPTVGSLTSL 2698
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
23-142 6.96e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 6.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARryvTALGPPQPRGSTD------SACAALPQPVPH 96
Cdd:PRK12323  418 AVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAAR---PAAAGPRPVAAAAaaaparAAPAAAPAPADD 494

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 568963928   97 EP---REAAFRLAPASERGASVSPARIPRRRRRVPAMWDPRAARTPPRE 142
Cdd:PRK12323  495 DPppwEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAP 543
PHA03247 PHA03247
large tegument protein UL36; Provisional
 23-141 7.54e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 7.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYVTALGPPQPRGSTDSACAALPQPVPHEPREAA 102
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 568963928  103 FRLAPASERGASVSPARIPRRRRRVPAMWDPRAA-RTPPR 141
Cdd:PHA03247 2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPpPPPPR 2938
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
314-667 8.71e-04

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 44.17  E-value: 8.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  314 YEKLEQVPKLVQWLVSIGANIETIGPNPLHALMRLCIQARESQLFRWVMDQKPEWKEHINHRDDAGCTVLHVAAAHfpgy 393
Cdd:COG0666    22 ALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARN---- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  394 tsrRQTEDVQMLLSFGADPTLLDGHARTVVdvlkrnknfraidkinshlekLASSSKGLSEIpaglvcdvnrdcattfIK 473
Cdd:COG0666    98 ---GDLEIVKLLLEAGADVNARDKDGETPL---------------------HLAAYNGNLEI----------------VK 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  474 FLLERqkwpevlllltrkvsgqpqlrnGVikDCDLSDLDICTviPHLSSWDQRKTQLLSRLIDSGALPEGLQDSQDRPLL 553
Cdd:COG0666   138 LLLEA----------------------GA--DVNAQDNDGNT--PLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLH 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  554 MCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLHAALHIfldINADIGFNFLSHLLDlflsnptefyylnPNVQDSNGNT 633
Cdd:COG0666   192 LAAENGHLEIVKLLLEAGADVNAKDN-DGKTALDLAAEN---GNLEIVKLLLEAGAD-------------LNAKDKDGLT 254

                         330       340       350
                  ....*....|....*....|....*....|....
gi 568963928  634 LMHLLFQKGMLKRTKKLIDLLVKFDINFNLKNKA 667
Cdd:COG0666   255 ALLLAAAAGAALIVKLLLLALLLLAAALLDLLTL 288
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
498-668 8.79e-04

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 44.17  E-value: 8.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  498 LRNGVIKDCDLSDLDICTVIPHLSSWDQRKTQLLSRLIDSGALPEGLQDSQDRPLLMCLRHEDFDLAFLLLTKGADPRSV 577
Cdd:COG0666     3 LLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  578 SLVEGDTPLHAALHiflDINADIgfnflshlLDLFLSNPtefyyLNPNVQDSNGNTLMHLLFQKGMLkrtkKLIDLLVKF 657
Cdd:COG0666    83 KDDGGNTLLHAAAR---NGDLEI--------VKLLLEAG-----ADVNARDKDGETPLHLAAYNGNL----EIVKLLLEA 142

                         170
                  ....*....|.
gi 568963928  658 DINFNLKNKAG 668
Cdd:COG0666   143 GADVNAQDNDG 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 134-217 1.07e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.60  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928  134 RAARTPPrELAMLLCNKSNAFYNLGKWNEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFfegLRLLQRSPD 213
Cdd:COG3914   137 RALALNP-DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAY---RRALELDPD 212


                  ....
gi 568963928  214 QLQV 217
Cdd:COG3914   213 NADA 216
PHA03247 PHA03247
large tegument protein UL36; Provisional
 22-144 1.19e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAklsAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYVTALGPPQPRGSTDSACAALP-QPVPHEPRE 100
Cdd:PHA03247 2765 GPPAPAPPA---APAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPtSAQPTAPPP 2841

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 568963928  101 AAFRLAPASERGASVSP----ARIPRRRRRVPAmwdPRAARTPP-RELA 144
Cdd:PHA03247 2842 PPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAK---PAAPARPPvRRLA 2887
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 23-141 1.29e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.78  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARRYVTALGPPQPRGSTDSACAALPQPVPHEPREAA 102
Cdd:PHA03307  261 APITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAA 340

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 568963928  103 FRLAPASERGASVSPARIPRRRrrvpamwDPRAARTPPR 141
Cdd:PHA03307  341 VSPGPSPSRSPSPSRPPPPADP-------SSPRKRPRPS 372
UvrD_C pfam13361
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
 205-340 1.30e-03

UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.


Pssm-ID: 433145 [Multi-domain]  Cd Length: 377  Bit Score: 43.93  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   205 LRLLQRSPdqLQVPDFLVGIFTTMSSIGM--SDPGGGDSIVL-QSFLPCFDH-------IFTTGFST---EVWQYVIQKL 271
Cdd:pfam13361  136 KRILNGPK--RGIGNATLERIREYKKRGLrlSDFINPDTLTYgDPFVIALEQdnivvfdVETTGLDTtedEIIQIAAIKL 213

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568963928   272 AKKG-LWHSFLLLSAKKDRLPSNIHVSELSLQSLFEKY-----VFIGFYEKLEQVPKLVQWLVSIGANIETIGPN 340
Cdd:pfam13361  214 NKKGvVIESFERFLRLKKPVGDSLQVHGFSDEFLQENGetpaeALRDFLEKLENLRELYSILREYDDIEETPEPE 288
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 26-140 1.51e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.32  E-value: 1.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   26 RAPGAKLSAPEAGPPRRGPLPRGGAGRdtllgAKATPssPAARRYVTALGPPQPRGSTDSACAALPQPVPHEPREAAFRL 105
Cdd:PRK14951  375 PAEKKTPARPEAAAPAAAPVAQAAAAP-----APAAA--PAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL 447

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 568963928  106 APASERGASVSPARIPRRRRRVPAMWDPRAARTPP 140
Cdd:PRK14951  448 APAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAA 482
PHA03247 PHA03247
large tegument protein UL36; Provisional
 22-140 1.62e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPG-----AKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSSPAARRyVTALGPPQ--PRGSTDSACAALPQ-P 93
Cdd:PHA03247 2721 LPPGPAAArqaspALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA-APAAGPPRrlTRPAVASLSESRESlP 2799

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 568963928   94 VPHEPREAAfrlAPASERGASVSPARIPRRRRRVPAMWDPRAARTPP 140
Cdd:PHA03247 2800 SPWDPADPP---AAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843
PHA03247 PHA03247
large tegument protein UL36; Provisional
 23-141 2.52e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 2.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAPGAKLSAPEAGPPRRgpLPRGGAGRDTLLGAKATPSSPAARryvTALGPPQPRGSTDSACAALPQPVPHEPREAA 102
Cdd:PHA03247 2866 PPSRSPAAKPAAPARPPVRR--LARPAVSRSTESFALPPDQPERPP---QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568963928  103 FRLAPASE--------------RGASVSPARIPRRRRRVPAMWDPR---AARTPPR 141
Cdd:PHA03247 2941 PPLAPTTDpagagepsgavpqpWLGALVPGRVAVPRFRVPQPAPSReapASSTPPL 2996
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
141-207 4.32e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 4.32e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568963928  141 RELAMLLCNKSNAFYNLGKWNEAFLAAKECLQWDPTYVKGYYRAGYSLLHLLQPYEAARMFFEGLRL 207
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL 105
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
22-139 4.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.56  E-value: 4.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPSsPAARRYVTALGPPQPRGSTDSACAALPQPVPheprea 101
Cdd:PRK12323  386 APAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRS-PAPEALAAARQASARGPGGAPAPAPAPAAAP------ 458

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 568963928  102 afrlAPAsERGASVSPARIPRRRRRVPAMWDPRAARTP 139
Cdd:PRK12323  459 ----AAA-ARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
Ank_2 pfam12796
Ankyrin repeats (3 copies);
552-665 4.37e-03

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 38.94  E-value: 4.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   552 LLMCLRHEDFDLAFLLLTKGADPRSVSLvEGDTPLHAAlhifldinADIG-FNFLSHLLDlflsnptefyYLNPNVQDsN 630
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDK-NGRTALHLA--------AKNGhLEIVKLLLE----------HADVNLKD-N 60

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 568963928   631 GNTLMHLLFQKGMLkrtkKLIDLLVKFDINFNLKN 665
Cdd:pfam12796   61 GRTALHYAARSGHL----EIVKLLLEKGADINVKD 91
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 373-435 5.71e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 42.19  E-value: 5.71e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568963928  373 NHRDDAGCTVLHVAAAHfpGYTSRrqtedVQMLLSFGADPTLLDGHARTVVDVLKRNkNFRAI 435
Cdd:PTZ00322  109 NCRDYDGRTPLHIACAN--GHVQV-----VRVLLEFGADPTLLDKDGKTPLELAEEN-GFREV 163
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1987-2144 5.77e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.29  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 1987 LAEAAELLNREGRREEAALLMKQHGCLLEAARLTANKDFQASCLLGVARFNVARDSdiehtkviLREALDLCYQTSQLA- 2065
Cdd:COG3914    38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--------YEEALALYRRALALNp 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928 2066 GIAEAQFLLGIILRDFQKLRDAFIKFDM-LNHSAGMVEALYEAASLCESEHQ---------KVLALAPGGLEVLLNLVRA 2135
Cdd:COG3914   110 DNAEALFNLGNLLLALGRLEEALAALRRaLALNPDFAEAYLNLGEALRRLGRleeaiaalrRALELDPDNAEALNNLGNA 189


                  ....*....
gi 568963928 2136 LKNVTNNAE 2144
Cdd:COG3914   190 LQDLGRLEE 198
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
22-144 6.55e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 6.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   22 TPRSRAPGAklSAPEAGPPRRGPLP-------RGGAGRDTLLGAKATPSSPAARRYVTALGPPQPRGSTDSACAALPQPV 94
Cdd:PRK07003  411 APKAAAAAA--ATRAEAPPAAPAPPatadrgdDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA 488

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 568963928   95 PHEPREAAFRLAPASERGASVSPARIPRRRRRVPAMWDPRAARTPPRELA 144
Cdd:PRK07003  489 AFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPA 538
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 23-142 8.46e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 8.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568963928   23 PRSRAPGAKLSAPEAGPPRRGPLPRGGAGRDTLLGAKATPS----SPAARRYVTALGPPQPRGSTDSACAALPQPVPHEP 98
Cdd:PRK07764  610 EEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPehhpKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAA 689

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 568963928   99 REAAFRLAPASERGASVSPARIPRRRRRVPAMWDPRAARTPPRE 142
Cdd:PRK07764  690 PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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