NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|568965686|ref|XP_006512933|]
View 

zinc finger-containing ubiquitin peptidase 1 isoform X1 [Mus musculus]

Protein Classification

C78 family peptidase( domain architecture ID 10546049)

C78 family peptidase is a cysteine peptidase similar to human Ufm1-specific protease 2 (UFSP2) which cleaves the peptide bond at the C-terminal Gly of ubiquitin-fold modifier-1 protein and to human zinc finger-containing ubiquitin peptidase 1 (ZUP1, also known as ZUFSP) which cleaves 'Lys-63'-linked long polyubiquitin chains

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 335-550 5.89e-76

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


:

Pssm-ID: 400318  Cd Length: 199  Bit Score: 239.49  E-value: 5.89e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  335 DVRCVWLSTVVDHF-HSSFGDKGWGCGYRNFQMLLSSLLQSDVYgdCLKGMAVPCIPKIQSMIEDAWNEGFDPQGasqln 413
Cdd:pfam07910   2 EVYLVLGSYDYYHYmQDGFNDKGWGCGYRNLQMLLSWLLLNGYT--GKPQFTVPTIPEIQQMLEDAWDKGFDSQG----- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  414 nkLQGTKAWIGACEIYTLLTSL-RVKCRIIDFhKSTGPLGTHPRLFEWILNYYSsetegtpkivCTSKPPIYLQHQGH-- 490
Cdd:pfam07910  75 --FVGSRKWIGTTEASAVLTSLlGVDCKIVDF-KSGSELGTHPELFDEVANYFE----------STSGPPIYLQHQGHvy 141

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568965686  491 SRTVVGIEEKKNRTLCLLVFDPGCPSRE--MQKLLKQDMEASSlrqlrKSVGNL-KHKQYQIV 550
Cdd:pfam07910 142 SRTILGVEINANGELNLLILDPHYTGADdsLKLVGDKGWVGWK-----KGVDFLkKHKFYNLC 199
 
Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 335-550 5.89e-76

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


Pssm-ID: 400318  Cd Length: 199  Bit Score: 239.49  E-value: 5.89e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  335 DVRCVWLSTVVDHF-HSSFGDKGWGCGYRNFQMLLSSLLQSDVYgdCLKGMAVPCIPKIQSMIEDAWNEGFDPQGasqln 413
Cdd:pfam07910   2 EVYLVLGSYDYYHYmQDGFNDKGWGCGYRNLQMLLSWLLLNGYT--GKPQFTVPTIPEIQQMLEDAWDKGFDSQG----- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  414 nkLQGTKAWIGACEIYTLLTSL-RVKCRIIDFhKSTGPLGTHPRLFEWILNYYSsetegtpkivCTSKPPIYLQHQGH-- 490
Cdd:pfam07910  75 --FVGSRKWIGTTEASAVLTSLlGVDCKIVDF-KSGSELGTHPELFDEVANYFE----------STSGPPIYLQHQGHvy 141

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568965686  491 SRTVVGIEEKKNRTLCLLVFDPGCPSRE--MQKLLKQDMEASSlrqlrKSVGNL-KHKQYQIV 550
Cdd:pfam07910 142 SRTILGVEINANGELNLLILDPHYTGADdsLKLVGDKGWVGWK-----KGVDFLkKHKFYNLC 199
 
Name Accession Description Interval E-value
Peptidase_C78 pfam07910
Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine ...
 335-550 5.89e-76

Peptidase family C78; This family formerly known as DUF1671 has been shown to be a cysteine peptidase called (Ufm1)-specific protease.


Pssm-ID: 400318  Cd Length: 199  Bit Score: 239.49  E-value: 5.89e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  335 DVRCVWLSTVVDHF-HSSFGDKGWGCGYRNFQMLLSSLLQSDVYgdCLKGMAVPCIPKIQSMIEDAWNEGFDPQGasqln 413
Cdd:pfam07910   2 EVYLVLGSYDYYHYmQDGFNDKGWGCGYRNLQMLLSWLLLNGYT--GKPQFTVPTIPEIQQMLEDAWDKGFDSQG----- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965686  414 nkLQGTKAWIGACEIYTLLTSL-RVKCRIIDFhKSTGPLGTHPRLFEWILNYYSsetegtpkivCTSKPPIYLQHQGH-- 490
Cdd:pfam07910  75 --FVGSRKWIGTTEASAVLTSLlGVDCKIVDF-KSGSELGTHPELFDEVANYFE----------STSGPPIYLQHQGHvy 141

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568965686  491 SRTVVGIEEKKNRTLCLLVFDPGCPSRE--MQKLLKQDMEASSlrqlrKSVGNL-KHKQYQIV 550
Cdd:pfam07910 142 SRTILGVEINANGELNLLILDPHYTGADdsLKLVGDKGWVGWK-----KGVDFLkKHKFYNLC 199
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH