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Conserved domains on  [gi|568978514|ref|XP_006515391|]
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tetratricopeptide repeat protein 7B isoform X4 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-394 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 690.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGidvhedq 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKG------- 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  241 qNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARV 320
Cdd:pfam19440 235 -NLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRV 312

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568978514  321 YSGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 394
Cdd:pfam19440 313 YSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
774-907 7.63e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 774 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 853
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 854 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 907
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 379-619 5.58e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 379 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 454
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 455 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 534
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 535 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 614
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978514 615 KHMLQ 619
Cdd:COG2956  269 ERQLR 273
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-394 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 690.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGidvhedq 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKG------- 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  241 qNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARV 320
Cdd:pfam19440 235 -NLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRV 312

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568978514  321 YSGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 394
Cdd:pfam19440 313 YSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
774-907 7.63e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 774 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 853
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 854 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 907
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 379-619 5.58e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 379 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 454
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 455 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 534
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 535 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 614
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978514 615 KHMLQ 619
Cdd:COG2956  269 ERQLR 273
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 748-921 4.19e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 63.46  E-value: 4.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  748 EQALSEVASSLQssapkqgpLHPWMTlaQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 827
Cdd:TIGR00990 348 LEALADLSKSIE--------LDPRVT--QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  828 ARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 907
Cdd:TIGR00990 418 AGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497

                         170
                  ....*....|....
gi 568978514  908 ASSPAVPFTVIPRV 921
Cdd:TIGR00990 498 KETKPMYMNVLPLI 511
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 351-913 4.40e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 4.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  351 AVLSRIPEHksdrLISLQSASvvydlltIALGRRGQYEMLSECLERAMKfAFEEFHLWYQF-ALSLMAAGKSARAVKVLK 429
Cdd:TIGR02917 286 DALKSAPEY----LPALLLAG-------ASEYQLGNLEQAYQYLNQILK-YAPNSHQARRLlASIQLRLGRVDEAIATLS 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  430 ECIRLKPDDATIPLLAAKLCVGSLHWLEEAEKFAKtvvdVGEKTSEFKAKgYLALGLTYslqatdaslrgMQEGLQRKAL 509
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAK----ATELDPENAAA-RTQLGISK-----------LSQGDPSEAI 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  510 LAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPE 589
Cdd:TIGR02917 418 ADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPD 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  590 NFILLFSKVKLESLCRGPDEALLTCKHMLQIwkscynltNPSDSG---RGSSLLDRTIADRRQLNTITLPDFSDPETVSD 666
Cdd:TIGR02917 498 FFPAAANLARIDIQEGNPDDAIQRFEKVLTI--------DPKNLRailALAGLYLRTGNEEEAVAWLEKAAELNPQEIEP 569

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  667 SSSSSSLSRTESPLHLFVS---SPLHSHPK-PDIFVWPPAAHSFSDPGPRHEPSFCNSPEAHFHGFPSLFSVSSVHATsv 742
Cdd:TIGR02917 570 ALALAQYYLGKGQLKKALAilnEAADAAPDsPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAV-- 647

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  743 aASRVEQALSEVASSLQssapkqgpLHPWMTLAQIWLhaAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELR 822
Cdd:TIGR02917 648 -MKNYAKAITSLKRALE--------LKPDNTEAQIGL--AQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQ 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  823 GHFDEARRWYEEALSISPTHVKSMQrLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLT 902
Cdd:TIGR02917 717 KDYPAAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQT 795

                         570
                  ....*....|.
gi 568978514  903 ALELEASSPAV 913
Cdd:TIGR02917 796 VVKKAPDNAVV 806
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 334-441 8.89e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 8.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 334 EEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFAL 413
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100
                 ....*....|....*....|....*...
gi 568978514 414 SLMAAGKSARAVKVLKECIRLKPDDATI 441
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNA 124
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 811-841 1.50e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.81  E-value: 1.50e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568978514  811 VLYMRGQVAELRGHFDEARRWYEEALSISPT 841
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 748-896 9.07e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 42.49  E-value: 9.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 748 EQALsEVASSLQSSapKQGPLHPwmTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 827
Cdd:PRK11788 158 QKAI-DVAERLEKL--GGDSLRV--EIAHFYCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAA 232

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 828 ARRWYEEALSISPTHV-KSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAA 896
Cdd:PRK11788 233 AIEALERVEEQDPEYLsEVLPKLMECYQALGDEAEGLEFLRRALEEYPGA-DLLLALAQLLEEQEGPEAA 301
pgaA PRK10049
outer membrane protein PgaA; Provisional
 490-611 1.86e-03

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 42.01  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 490 LQATDASLRGMQEglQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSA 569
Cdd:PRK10049  52 YAAVAVAYRNLKQ--WQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKANLLALAYVYKRA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978514 570 QKHYhDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 611
Cdd:PRK10049 130 GRHW-DELRAMTQALPRAPQTQQYPTEYVQALRNNRLSAPAL 170
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 409-590 5.85e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 5.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  409 YQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSlhwleeaEKFaKTVVDVGEKTSEFKAKGYLALgltY 488
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ-------GKF-QQVLDELPGKTLLDDEGAAEL---L 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  489 SLQATDASLRGMQEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLS 568
Cdd:TIGR02917 129 ALRGLAYLGLGQLE----LAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLL 204

                         170       180
                  ....*....|....*....|..
gi 568978514  569 AQKHYHDALNIIDMALSEYPEN 590
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNN 226
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 822-906 7.60e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 822 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA-HEVWNGLGEVLqaQGNDAAatECF 900
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLS--GGEEAL--QYY 88


                 ....*.
gi 568978514 901 LTALEL 906
Cdd:cd24142   89 EKGIEI 94
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 1-394 0e+00

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 690.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514    1 MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRK 80
Cdd:pfam19440   3 SRISFSGYRLETEIERCRSECQWDKVPELVEQLKAKRIANDDMANLLLGEGKLEQYLKENPPILENSTEKNQPKLSEAKK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514   81 HLTAALDRGNLKSEFLQESNLVMAKLTYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRMIAEAYATKGLCLEKLPVSSS 160
Cdd:pfam19440  83 HLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  161 TSNLHVDREQDVITCYEKAGDIALLYLQEIERVMlTNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGidvhedq 240
Cdd:pfam19440 163 SRVRLAEREEEMITCYEKAGDIALLYLQELERIN-SNTQNRSPKPGPPSQEQELGFFLETALQRAYVLYFKKG------- 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  241 qNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLrKGANTKAYTLPRRARV 320
Cdd:pfam19440 235 -NLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPL-KGTNTKNYTPSRKPRV 312

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568978514  321 YSGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECL 394
Cdd:pfam19440 313 YSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
774-907 7.63e-22

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 95.84  E-value: 7.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 774 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 853
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 854 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 907
Cdd:COG0457   87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 772-913 9.59e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 94.67  E-value: 9.59e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 772 MTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLAL 851
Cdd:COG3914   75 LLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978514 852 VLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 775-908 1.22e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 80.24  E-value: 1.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEA 908
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
775-908 5.31e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.59  E-value: 5.31e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG0457   42 AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEA 908
Cdd:COG0457  122 ELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
804-913 2.34e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 79.67  E-value: 2.34e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 804 LFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGL 883
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110
                 ....*....|....*....|....*....|
gi 568978514 884 GEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEA 112
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 775-913 5.93e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.31  E-value: 5.93e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 739-913 2.29e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.34  E-value: 2.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 739 ATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQV 818
Cdd:COG3914    8 ALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 819 AELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATE 898
Cdd:COG3914   88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                        170
                 ....*....|....*
gi 568978514 899 CFLTALELEASSPAV 913
Cdd:COG3914  168 ALRRALELDPDNAEA 182
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 811-913 3.04e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 70.61  E-value: 3.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 811 VLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQ 890
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100
                 ....*....|....*....|...
gi 568978514 891 GNDAAATECFLTALELEASSPAV 913
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEA 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 775-905 3.75e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 3.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG2956  144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAATECFLTALE 905
Cdd:COG2956  224 KLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 775-913 1.46e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.07  E-value: 1.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG2956   76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG2956  156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPA 214
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 778-906 3.07e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 3.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 778 WLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLG 857
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 568978514 858 RYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 906
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 775-913 6.15e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 6.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG2956   42 VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE 121

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG2956  122 QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA 180
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 775-873 1.40e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 65.41  E-value: 1.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG4235   17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                         90
                 ....*....|....*....
gi 568978514 855 QLGRYSLAEKILRDAVQVN 873
Cdd:COG4235   97 QQGDYAEAIAAWQKLLALL 115
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 743-873 4.07e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 64.98  E-value: 4.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 743 AASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELR 822
Cdd:COG5010   22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568978514 823 GHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVN 873
Cdd:COG5010  102 GDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 775-917 5.12e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.64  E-value: 5.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVW-NGLGEVLQAQGNDAAATECFLTALELEASSPAVPFTV 917
Cdd:COG3914  192 DLGRLEEAIAAYRRALELDPDNADAHsNLLFALRQACDWEVYDRFEELLAALARGPSELSPFAL 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
818-909 5.29e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.88  E-value: 5.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 818 VAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKiLRDAVQVNSTAHEVWNGLGEVLQAQGNDAAAT 897
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 568978514 898 ECFLTALELEAS 909
Cdd:COG3063   80 AYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 379-619 5.58e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 5.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 379 IALG----RRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLH 454
Cdd:COG2956   46 LALGnlyrRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 455 WlEEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLA 534
Cdd:COG2956  126 W-EKAIEVLERLLKLGPENAHA----YCELAELY-----------LEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 535 ISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENfILLFSKVKLESLCRGPDEALLTC 614
Cdd:COG2956  190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALL 268


                 ....*
gi 568978514 615 KHMLQ 619
Cdd:COG2956  269 ERQLR 273
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 793-906 1.15e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 63.10  E-value: 1.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 793 EATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQV 872
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 568978514 873 NSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 906
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 818-907 2.51e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.67  E-value: 2.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 818 VAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAAT 897
Cdd:COG5010   63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK 142

                         90
                 ....*....|
gi 568978514 898 ECFLTALELE 907
Cdd:COG5010  143 AALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
784-878 2.83e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.57  E-value: 2.83e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 784 VYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRwYEEALSISPTHVKSMQRLALVLHQLGRYSLAE 863
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....*
gi 568978514 864 KILRDAVQVNSTAHE 878
Cdd:COG3063   80 AYLERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 408-620 4.17e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 4.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 408 WYQFALSLMAAGKSARAVKVLKECIRLKPDDAtipllAAKLCVGSLHW----LEEAEKFAKTVVDVGEKtsefKAKGYLA 483
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETV-----EAHLALGNLYRrrgeYDRAIRIHQKLLERDPD----RAEALLE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 484 LGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLL 563
Cdd:COG2956   82 LAQDY-----------LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCEL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568978514 564 ALLLSAQKHYHDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEALLTCKHMLQI 620
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ 207
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
760-905 7.22e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 63.01  E-value: 7.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 760 SSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSIS 839
Cdd:COG4785   58 LAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 840 PTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHE--VWNGL------------------GEVLQAQGNDAAATEC 899
Cdd:COG4785  138 PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPEraLWLYLaerkldpekalallledwATAYLLQGDTEEAREL 217


                 ....*.
gi 568978514 900 FLTALE 905
Cdd:COG4785  218 FKLALA 223
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 748-921 4.19e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 63.46  E-value: 4.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  748 EQALSEVASSLQssapkqgpLHPWMTlaQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 827
Cdd:TIGR00990 348 LEALADLSKSIE--------LDPRVT--QSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQ 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  828 ARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 907
Cdd:TIGR00990 418 AGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELE 497

                         170
                  ....*....|....
gi 568978514  908 ASSPAVPFTVIPRV 921
Cdd:TIGR00990 498 KETKPMYMNVLPLI 511
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
373-594 1.08e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 373 VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpLLAAKLCVGS 452
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA-LNNLGLALQA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 453 LHWLEEAEKFAKTVVDVGEKtsefKAKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQ 532
Cdd:COG0457   89 LGRYEEALEDYDKALELDPD----DAEALYNLGLAL-----------LELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978514 533 LAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILL 594
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILT 215
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 775-915 1.19e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.41  E-value: 1.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLY-MRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 853
Cdd:TIGR02917  90 NQVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAELLaLRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLA 169

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978514  854 HQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 915
Cdd:TIGR02917 170 LAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLL 231
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 813-913 7.85e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 7.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 813 YMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGN 892
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100
                 ....*....|....*....|.
gi 568978514 893 DAAATECFLTALELEASSPAV 913
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEA 112
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 500-620 4.39e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 4.39e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 500 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 579
Cdd:COG3914   89 QALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978514 580 IDMALSEYPENFILLFSKVK-LESLCRgPDEALLTCKHMLQI 620
Cdd:COG3914  169 LRRALELDPDNAEALNNLGNaLQDLGR-LEEAIAAYRRALEL 209
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 478-590 4.99e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 4.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 478 AKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDA 557
Cdd:COG4235   17 AEGWLLLGRAY-----------LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110
                 ....*....|....*....|....*....|...
gi 568978514 558 NSLHLLALLLSAQKHYHDALNIIDMALSEYPEN 590
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
836-913 8.32e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 8.32e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978514 836 LSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 774-881 1.31e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.38  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 774 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVL 853
Cdd:COG3914  145 FAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224

                         90       100
                 ....*....|....*....|....*...
gi 568978514 854 HQLGRYSLAEKILRDAVQVNSTAHEVWN 881
Cdd:COG3914  225 RQACDWEVYDRFEELLAALARGPSELSP 252
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 367-557 3.76e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.84  E-value: 3.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 367 LQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaa 446
Cdd:COG3914   74 LLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEA----- 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 447 klcvgslhwleeaekfaktvvdvgektsefkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAA 526
Cdd:COG3914  149 ----------------------------------YLNLGEAL-----------RRLGRLEEAIAALRRALELDPDNAEAL 183

                        170       180       190
                 ....*....|....*....|....*....|.
gi 568978514 527 FYLALQLAISRQIPEALGYVRQALQLQGDDA 557
Cdd:COG3914  184 NNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 775-912 5.85e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 5.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  775 AQIWLHAAEVYIGIGKPAEATACTQEAANL----FPMSHNVLymrgQVAELRGHFDEARRWYEEALSISPTHVKSMQRLA 850
Cdd:TIGR02917 465 ASLHNLLGAIYLGKGDLAKAREAFEKALSIepdfFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALA 540

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978514  851 LVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPA 912
Cdd:TIGR02917 541 GLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPE 602
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 408-556 1.22e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 1.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 408 WYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLHWlEEAEKFAKTVVDVGEKTSEFkakgYLALGLT 487
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL-DEAIVLLHEALELDPDEPEA----RLNLGLA 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568978514 488 YslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDD 556
Cdd:COG4783   82 L-----------LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 789-871 1.50e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.68  E-value: 1.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 789 GKPAEATACTQEAANLFPMSH---NVLYMRGQVAELRGHFDEARRWYEEALSISPTHVK---SMQRLALVLHQLGRYSLA 862
Cdd:COG1729    7 GDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKA 86


                 ....*....
gi 568978514 863 EKILRDAVQ 871
Cdd:COG1729   87 RATLEELIK 95
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 269-543 1.98e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.53  E-value: 1.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 269 IARQLAEILLRGMCEQSYWSPLEEPPYQSPLDDPLRKGANTKAYTLPRRARVYSGENIFCPQENTEEALLLLLISESMAN 348
Cdd:COG3914   21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALAL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 349 RDAVLSRIPEHksdrlislqsaSVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVL 428
Cdd:COG3914  101 YRRALALNPDN-----------AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAAL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 429 KECIRLKPDDATIPLLAAKLCvGSLHWLEEAEKFAKTVVDVgeKTSEFKAKGYLALGLTYS-----LQATDASLRGMQEG 503
Cdd:COG3914  170 RRALELDPDNAEALNNLGNAL-QDLGRLEEAIAAYRRALEL--DPDNADAHSNLLFALRQAcdwevYDRFEELLAALARG 246

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 568978514 504 LQRKALLAFQRAHSLSPTDHqaafyLALQLAISRQIPEAL 543
Cdd:COG3914  247 PSELSPFALLYLPDDDPAEL-----LALARAWAQLVAAAA 281
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 775-840 2.69e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 2.69e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 840
Cdd:COG4235   51 ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 392-558 3.20e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 3.20e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 392 ECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaaklcvgslhwleeaekfaktvvdvge 471
Cdd:COG4235    4 ARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADA------------------------------ 53

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 472 ktsefkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQ 551
Cdd:COG4235   54 ---------LLDLAEAL-----------LAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113


                 ....*..
gi 568978514 552 LQGDDAN 558
Cdd:COG4235  114 LLPADAP 120
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 351-913 4.40e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 4.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  351 AVLSRIPEHksdrLISLQSASvvydlltIALGRRGQYEMLSECLERAMKfAFEEFHLWYQF-ALSLMAAGKSARAVKVLK 429
Cdd:TIGR02917 286 DALKSAPEY----LPALLLAG-------ASEYQLGNLEQAYQYLNQILK-YAPNSHQARRLlASIQLRLGRVDEAIATLS 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  430 ECIRLKPDDATIPLLAAKLCVGSLHWLEEAEKFAKtvvdVGEKTSEFKAKgYLALGLTYslqatdaslrgMQEGLQRKAL 509
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAK----ATELDPENAAA-RTQLGISK-----------LSQGDPSEAI 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  510 LAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPE 589
Cdd:TIGR02917 418 ADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPD 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  590 NFILLFSKVKLESLCRGPDEALLTCKHMLQIwkscynltNPSDSG---RGSSLLDRTIADRRQLNTITLPDFSDPETVSD 666
Cdd:TIGR02917 498 FFPAAANLARIDIQEGNPDDAIQRFEKVLTI--------DPKNLRailALAGLYLRTGNEEEAVAWLEKAAELNPQEIEP 569

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  667 SSSSSSLSRTESPLHLFVS---SPLHSHPK-PDIFVWPPAAHSFSDPGPRHEPSFCNSPEAHFHGFPSLFSVSSVHATsv 742
Cdd:TIGR02917 570 ALALAQYYLGKGQLKKALAilnEAADAAPDsPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAV-- 647

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  743 aASRVEQALSEVASSLQssapkqgpLHPWMTLAQIWLhaAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELR 822
Cdd:TIGR02917 648 -MKNYAKAITSLKRALE--------LKPDNTEAQIGL--AQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQ 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  823 GHFDEARRWYEEALSISPTHVKSMQrLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLT 902
Cdd:TIGR02917 717 KDYPAAIQAYRKALKRAPSSQNAIK-LHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQT 795

                         570
                  ....*....|.
gi 568978514  903 ALELEASSPAV 913
Cdd:TIGR02917 796 VVKKAPDNAVV 806
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
408-611 5.04e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 5.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 408 WYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpllaaklcvgslhwleeaekfaktvvdvgektsefkakgYLALGLT 487
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---------------------------------------LYNLGLA 51

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 488 YslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLL 567
Cdd:COG0457   52 Y-----------LRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLAL 120

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 568978514 568 SAQKHYHDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 611
Cdd:COG0457  121 LELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEAL 164
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 362-448 1.81e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 1.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 362 DRLISLQSASV-VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDAT 440
Cdd:COG4783   28 EKALELDPDNPeAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE 107


                 ....*...
gi 568978514 441 IPLLAAKL 448
Cdd:COG4783  108 AYLRLARA 115
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
812-911 2.40e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 2.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 812 LYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQG 891
Cdd:COG4785   76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                         90       100
                 ....*....|....*....|
gi 568978514 892 NDAAATECFLTALELEASSP 911
Cdd:COG4785  156 RYELAIADLEKALELDPNDP 175
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
775-840 3.07e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 3.07e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACtQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 840
Cdd:COG3063   26 ADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDP 90
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 500-620 3.13e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 3.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 500 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 579
Cdd:COG4783   15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALAL 94

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 568978514 580 IDMALSEYPENFILLFSKVKLESLCRGPDEALLTCKHMLQI 620
Cdd:COG4783   95 LEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 500-588 4.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 4.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 500 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 579
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                 ....*....
gi 568978514 580 IDMALSEYP 588
Cdd:COG5010  145 LQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 827-913 6.88e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 6.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 827 EARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALEL 906
Cdd:COG5010   38 KEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117


                 ....*..
gi 568978514 907 EASSPAV 913
Cdd:COG5010  118 SPDNPNA 124
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 334-441 8.89e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 8.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 334 EEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFAL 413
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100
                 ....*....|....*....|....*...
gi 568978514 414 SLMAAGKSARAVKVLKECIRLKPDDATI 441
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNA 124
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 848-915 9.15e-05

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 43.05  E-value: 9.15e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978514  848 RLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 915
Cdd:TIGR02552  22 ALAYNLYQQGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYF 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 376-594 1.06e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 1.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 376 LLTIALGRRGQYEMLSECLERAMKFAFEEFH---------LWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAA 446
Cdd:COG3914    6 LLALAALAAAALLAAAAAAELALAAELEAAAlaaalglalLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 447 KLCVgSLHWLEEAEKFAKTVVDVGEKTsefkAKGYLALGLTYSLQatdaslrgmqeGLQRKALLAFQRAHSLSPTDHQAA 526
Cdd:COG3914   86 LLLQ-ALGRYEEALALYRRALALNPDN----AEALFNLGNLLLAL-----------GRLEEALAALRRALALNPDFAEAY 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978514 527 FYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILL 594
Cdd:COG3914  150 LNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 811-841 1.50e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.81  E-value: 1.50e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568978514  811 VLYMRGQVAELRGHFDEARRWYEEALSISPT 841
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 775-913 2.24e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:TIGR02917 736 SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL 815

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568978514  855 QLGR---YSLAEKilrdAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAV 913
Cdd:TIGR02917 816 ELKDpraLEYAER----ALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAI 873
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 377-522 5.22e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 5.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 377 LTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVgSLHWL 456
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL-KAGDY 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978514 457 EEAEKFAKTVVDVGEKTSEFkakgYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTD 522
Cdd:COG4783   89 DEALALLEKALKLDPEHPEA----YLRLARAY-----------RALGRPDEAIAALEKALELDPDD 139
TPR_19 pfam14559
Tetratricopeptide repeat;
823-890 5.80e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.10  E-value: 5.80e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978514  823 GHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNglgevLQAQ 890
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA-----LLAK 64
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
500-589 6.02e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 6.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 500 MQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYvRQALQLQGDDANSLHLLALLLSAQKHYHDALNI 579
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 568978514 580 IDMALSEYPE 589
Cdd:COG3063   82 LERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 764-840 6.82e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 6.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 764 KQGPLHPWMTLAQIWLhaAEVYIGIGKPAEATACTQEAANLFPMSHNV---LYMRGQVAELRGHFDEARRWYEEALSISP 840
Cdd:COG1729   21 KRYPNSPLAPDALYWL--GEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKKYP 98
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 775-840 7.09e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 7.09e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISP 840
Cdd:COG5010   88 PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 785-896 7.36e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 7.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  785 YIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEK 864
Cdd:TIGR02917 135 YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALA 214

                          90       100       110
                  ....*....|....*....|....*....|..
gi 568978514  865 ILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAA 896
Cdd:TIGR02917 215 AYRKAIALRPNNIAVLLALATILIEAGEFEEA 246
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 368-553 7.56e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 7.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 368 QSASVVYDLLTIALgRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAK 447
Cdd:COG2956  108 DDAEALRLLAEIYE-QEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAE 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 448 LcvgsLHWLEEAEKFAKTVVDVGEKTSEFkAKGYLALGLTYslqatdaslrgMQEGLQRKALLAFQRAHSLSPTDHqAAF 527
Cdd:COG2956  187 L----YLEQGDYEEAIAALERALEQDPDY-LPALPRLAELY-----------EKLGDPEEALELLRKALELDPSDD-LLL 249

                        170       180
                 ....*....|....*....|....*.
gi 568978514 528 YLALQLAISRQIPEALGYVRQALQLQ 553
Cdd:COG2956  250 ALADLLERKEGLEAALALLERQLRRH 275
TPR_12 pfam13424
Tetratricopeptide repeat;
848-906 8.80e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 8.80e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978514  848 RLALVLHQLGRYSLAEKILRDAVQVNSTAH--------EVWNGLGEVLQAQGNDAAATECFLTALEL 906
Cdd:pfam13424   8 NLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALAL 74
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 742-913 9.02e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 9.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  742 VAASRVEQALSeVASSLQssapKQGPLHpwmtlAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMrGQVAEL 821
Cdd:TIGR02917 680 LAAKRTESAKK-IAKSLQ----KQHPKA-----ALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKL-HRALLA 748

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  822 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQaQGNDAAATECFL 901
Cdd:TIGR02917 749 SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYL-ELKDPRALEYAE 827

                         170
                  ....*....|..
gi 568978514  902 TALELEASSPAV 913
Cdd:TIGR02917 828 RALKLAPNIPAI 839
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 748-896 9.07e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 42.49  E-value: 9.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 748 EQALsEVASSLQSSapKQGPLHPwmTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDE 827
Cdd:PRK11788 158 QKAI-DVAERLEKL--GGDSLRV--EIAHFYCELAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAA 232

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 828 ARRWYEEALSISPTHV-KSMQRLALVLHQLGRYSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAA 896
Cdd:PRK11788 233 AIEALERVEEQDPEYLsEVLPKLMECYQALGDEAEGLEFLRRALEEYPGA-DLLLALAQLLEEQEGPEAA 301
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 775-842 1.68e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 1.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTH 842
Cdd:COG4783   72 PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
373-539 1.73e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 1.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 373 VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIpLLAAKLCVGS 452
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA-LYNLGIALEK 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 453 LHWLEEAEKFAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEGLQRKALLAFQRAHSLSPTDHQAAFYLALQ 532
Cdd:COG0457  157 LGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLA 236


                 ....*..
gi 568978514 533 LAISRQI 539
Cdd:COG0457  237 ALALYQY 243
pgaA PRK10049
outer membrane protein PgaA; Provisional
 490-611 1.86e-03

outer membrane protein PgaA; Provisional


Pssm-ID: 236644 [Multi-domain]  Cd Length: 765  Bit Score: 42.01  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 490 LQATDASLRGMQEglQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSA 569
Cdd:PRK10049  52 YAAVAVAYRNLKQ--WQNSLTLWQKALSLEPQNDDYQRGLILTLADAGQYDEALVKAKQLVSGAPDKANLLALAYVYKRA 129

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978514 570 QKHYhDALNIIDMALSEYPENFILLFSKVKLESLCRGPDEAL 611
Cdd:PRK10049 130 GRHW-DELRAMTQALPRAPQTQQYPTEYVQALRNNRLSAPAL 170
TPR_12 pfam13424
Tetratricopeptide repeat;
774-838 2.42e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.42e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568978514  774 LAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSH--------NVLYMRGQVAELRGHFDEARRWYEEALSI 838
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALAL 74
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 823-912 3.70e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 39.84  E-value: 3.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 823 GHFDEARRWYEEALSISPTH-VKSM--QRLALVLHQLGRYSLAEKILrDAVQVNSTAHEVWNGLGEVLQAQGNDAAATEC 899
Cdd:COG2976  104 GDLDKAAAQLQWVLDNAKDPaLKALarLRLARVLLAQKKYDEALATL-DAVKPEAFAALYAELRGDILLAQGDKAEARAA 182

                         90
                 ....*....|...
gi 568978514 900 FLTALELEASSPA 912
Cdd:COG2976  183 YQKALAALPEDAP 195
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 507-595 4.04e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 4.04e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 507 KALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSE 586
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*....
gi 568978514 587 YPENFILLF 595
Cdd:COG4235   81 DPDNPEALY 89
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 822-914 4.91e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 4.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 822 RGHFDEARRWYEEALSISPTHVKSMQ---RLALVLHQLGRYSLAEKILRDAVQV---NSTAHEVWNGLGEVLQAQGNDAA 895
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELGDYDK 85

                         90
                 ....*....|....*....
gi 568978514 896 ATECFLTALELEASSPAVP 914
Cdd:COG1729   86 ARATLEELIKKYPDSEAAK 104
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
775-896 5.12e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 5.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 775 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLH 854
Cdd:COG0457  110 AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALA 189

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 568978514 855 QLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAA 896
Cdd:COG0457  190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 374-446 5.24e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 5.24e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568978514 374 YDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAA 446
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 409-590 5.85e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 5.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  409 YQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSlhwleeaEKFaKTVVDVGEKTSEFKAKGYLALgltY 488
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ-------GKF-QQVLDELPGKTLLDDEGAAEL---L 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  489 SLQATDASLRGMQEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLS 568
Cdd:TIGR02917 129 ALRGLAYLGLGQLE----LAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLL 204

                         170       180
                  ....*....|....*....|..
gi 568978514  569 AQKHYHDALNIIDMALSEYPEN 590
Cdd:TIGR02917 205 SLGNIELALAAYRKAIALRPNN 226
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 813-876 7.34e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.16  E-value: 7.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978514  813 YMRGQVAELRGHFDEARRWYEEAL---SISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA 876
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 822-906 7.60e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 7.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 822 RGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEKILRDAVQVNSTA-HEVWNGLGEVLqaQGNDAAatECF 900
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGgYEKYLYLGQLS--GGEEAL--QYY 88


                 ....*.
gi 568978514 901 LTALEL 906
Cdd:cd24142   89 EKGIEI 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 780-871 8.01e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 8.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514  780 HAAEVYIGI--GKPAEATACTQEAANLFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRLALVLHQLG 857
Cdd:TIGR02917 230 LLALATILIeaGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLG 309

                          90
                  ....*....|....
gi 568978514  858 RYSLAEKILRDAVQ 871
Cdd:TIGR02917 310 NLEQAYQYLNQILK 323
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
782-912 8.08e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.09  E-value: 8.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 782 AEVYIGIGKPAEATACTQEAAN-LFPMSHNVLYMRGQVAELRGHFDEARRWYEEALSISPTHVKSMQRL--ALVLHQLGR 858
Cdd:COG4700   96 ADALLELGRYDEAIELYEEALTgIFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFKSSDAHLlyARALEALGD 175

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568978514 859 YSLAEKILRDAVQVNSTAhEVWNGLGEVLQAQGNDAAATECFLTALELEASSPA 912
Cdd:COG4700  176 LEAAEAELEALARRYSGP-EARYRYAKFLARQGRTAEAKELLEEILDEAKHMPK 228
PRK12370 PRK12370
HilA/EilA family virulence transcriptional regulator;
423-553 9.53e-03

HilA/EilA family virulence transcriptional regulator;


Pssm-ID: 237080 [Multi-domain]  Cd Length: 553  Bit Score: 39.45  E-value: 9.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568978514 423 RAVKVLKECIRLKPDDaTIPLLAAKLCVGSLHWL--EEAEKFAKTVVDVGEKTSEFKAKGYLALGLTyslqATDASLRGM 500
Cdd:PRK12370 279 QALKLLTQCVNMSPNS-IAPYCALAECYLSMAQMgiFDKQNAMIKAKEHAIKATELDHNNPQALGLL----GLINTIHSE 353

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 568978514 501 QEglqrKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQ 553
Cdd:PRK12370 354 YI----VGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEALQTINECLKLD 402
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 849-915 9.63e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.15  E-value: 9.63e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568978514 849 LALVLHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPF 915
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKY 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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