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Conserved domains on  [gi|568988475|ref|XP_006519462|]
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N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1 [Mus musculus]

Protein Classification

PEP_TPR_lipo and NARP1 domain-containing protein( domain architecture ID 12117197)

PEP_TPR_lipo and NARP1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 55-566 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


:

Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 779.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   55 YEYSELLLYQNQVMREANLFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEK 134
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  135 ALQLRSLD--ERLQLYEEVSKQHPRAVSPRRLPLSFAPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYCDTEKVSIIQE 212
Cdd:pfam12569  81 ALGISKEDheALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEKVDIIEE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  213 LVTNYEASLKMNGYFSPYENG--EKEPPTTLIWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMG 290
Cdd:pfam12569 161 LVEGYVSSLKTNGKFSGSDNGdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKARIYKHAG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  291 NLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTREGTSAMENLNEMQCMWFETECISAYQRLGRYG 370
Cdd:pfam12569 241 DLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGVGALGNLNEMQCMWFLTEDGEAYQRQGKYG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  371 DALKKCHEVERHFLEITDDQFDFHTYCMRKMTLRAYVGLLRLEDALRRHTFYFKAARSAIEIYLKLHDNPLTNDSKQQDI 450
Cdd:pfam12569 321 LALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKEGPEEEG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  451 DSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKReeEEEVTSGHKEELIPEKLERVDNPLEEAIKFLT 530
Cdd:pfam12569 401 DNGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKG--EDGETKKEDPDPLGEKLAQTEDPLEEAMKFLK 478

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 568988475  531 PLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRA 566
Cdd:pfam12569 479 PLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKAA 514
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 55-566 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 779.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   55 YEYSELLLYQNQVMREANLFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEK 134
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  135 ALQLRSLD--ERLQLYEEVSKQHPRAVSPRRLPLSFAPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYCDTEKVSIIQE 212
Cdd:pfam12569  81 ALGISKEDheALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEKVDIIEE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  213 LVTNYEASLKMNGYFSPYENG--EKEPPTTLIWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMG 290
Cdd:pfam12569 161 LVEGYVSSLKTNGKFSGSDNGdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKARIYKHAG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  291 NLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTREGTSAMENLNEMQCMWFETECISAYQRLGRYG 370
Cdd:pfam12569 241 DLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGVGALGNLNEMQCMWFLTEDGEAYQRQGKYG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  371 DALKKCHEVERHFLEITDDQFDFHTYCMRKMTLRAYVGLLRLEDALRRHTFYFKAARSAIEIYLKLHDNPLTNDSKQQDI 450
Cdd:pfam12569 321 LALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKEGPEEEG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  451 DSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKReeEEEVTSGHKEELIPEKLERVDNPLEEAIKFLT 530
Cdd:pfam12569 401 DNGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKG--EDGETKKEDPDPLGEKLAQTEDPLEEAMKFLK 478

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 568988475  531 PLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRA 566
Cdd:pfam12569 479 PLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKAA 514
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 243-374 1.86e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 1.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 243 WVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLR 322
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568988475 323 ANMIKEAEEMCSRFTREGTSAMENLNEMQcmwfeteciSAYQRLGRYGDALK 374
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLA---------RAYRALGRPDEAIA 127
 
Name Accession Description Interval E-value
NatA_aux_su pfam12569
N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal ...
 55-566 0e+00

N-terminal acetyltransferase A, auxiliary subunit; This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit (also known as NMDA receptor-regulated protein 1), which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation.


Pssm-ID: 463630 [Multi-domain]  Cd Length: 514  Bit Score: 779.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   55 YEYSELLLYQNQVMREANLFQESLEHIETYEKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEK 134
Cdd:pfam12569   1 YEHSELLLYKNQIIAESGDLEEALEHLEKVEKQIVDKLAVLETKADYLLKLGRKEEAEATYRALLERNPENHAYYEGLEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  135 ALQLRSLD--ERLQLYEEVSKQHPRAVSPRRLPLSFAPGKKFRELMDKFLRPNFSKGCPPLFTTLKSLYCDTEKVSIIQE 212
Cdd:pfam12569  81 ALGISKEDheALLALYDELAEKYPRSDAPRRLPLDFLEGEEFKELADKYLRRMLRKGVPSLFVNLKSLYTDSEKVDIIEE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  213 LVTNYEASLKMNGYFSPYENG--EKEPPTTLIWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMG 290
Cdd:pfam12569 161 LVEGYVSSLKTNGKFSGSDNGdgEKEPPSTLLWTYYFLAQHYDYLGSYEKALEYIDKAIDHTPTLIELYMTKARIYKHAG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  291 NLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEEMCSRFTREGTSAMENLNEMQCMWFETECISAYQRLGRYG 370
Cdd:pfam12569 241 DLQKAAEWMDEARSLDLADRYINSKCAKYMLRANEVEEAEETCSKFTRNGVGALGNLNEMQCMWFLTEDGEAYQRQGKYG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  371 DALKKCHEVERHFLEITDDQFDFHTYCMRKMTLRAYVGLLRLEDALRRHTFYFKAARSAIEIYLKLHDNPLTNDSKQQDI 450
Cdd:pfam12569 321 LALKRFHAVEKHFDEWEEDQFDFHTYCLRKMTLRAYVDMLRWEDRLRSHPFYFKAAKGAIEVYLRLHDKPLLKEGPEEEG 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  451 DSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKReeEEEVTSGHKEELIPEKLERVDNPLEEAIKFLT 530
Cdd:pfam12569 401 DNGNLSPAERKKARKKQKKAEKKAEKEEAEKAAKKKKKKAEKKAKG--EDGETKKEDPDPLGEKLAQTEDPLEEAMKFLK 478

                         490       500       510
                  ....*....|....*....|....*....|....*.
gi 568988475  531 PLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRA 566
Cdd:pfam12569 479 PLLKLAPDNIETHLLAFEVYIRKKKYLLALQCLKAA 514
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 243-374 1.86e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 1.86e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 243 WVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLR 322
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568988475 323 ANMIKEAEEMCSRFTREGTSAMENLNEMQcmwfeteciSAYQRLGRYGDALK 374
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLA---------RAYRALGRPDEAIA 127
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 15-157 1.92e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 1.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  15 QRASWIGYAIAYHLLKDYDTALKLLEEFRQTQqvPPNKIAYEY-SELLLYQNQVMREANLFQESLE----HIETYEKLic 89
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEAFALlGEILLQLGDLDEAIVLLHEALEldpdEPEARLNL-- 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568988475  90 dkllveeikGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKALQ-LRSLDERLQLYEEVSKQHPR 157
Cdd:COG4783   79 ---------GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRaLGRPDEAIAALEKALELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 55-332 1.27e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  55 YEYSELLLYQNQVMREANLFQESL----EHIETYEKLicdkllveeikGEMLLKLGRLKEASEVFRNLIDWNAENWCYYE 130
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALeldpETVEAHLAL-----------GNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 131 GLEKA-LQLRSLDERLQLYEEVSKQHPRAVSPRR-LPLSFAPGKKFRELMDKFLR-PNFSKGCPPLFTTLKSLYCDTEKv 207
Cdd:COG2956   81 ELAQDyLKAGLLDRAEELLEKLLELDPDDAEALRlLAEIYEQEGDWEKAIEVLERlLKLGPENAHAYCELAELYLEQGD- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 208 siIQELVTNYEASLKMNGYFSPyengekeppttliwVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYK 287
Cdd:COG2956  160 --YDEAIEALEKALKLDPDCAR--------------ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 568988475 288 HMGNLKEAAQWMDEAQSLDTADRFINSKcAKYMLRANMIKEAEEM 332
Cdd:COG2956  224 KLGDPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALAL 267
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
246-381 2.17e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.54  E-value: 2.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 246 YFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANM 325
Cdd:COG0457   46 YNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGR 125

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568988475 326 IKEAEEMCSRFTREGTSAMENLNEMQCmwfetecisAYQRLGRYGDALKKCHEVER 381
Cdd:COG0457  126 YDEAIEAYERALELDPDDADALYNLGI---------ALEKLGRYEEALELLEKLEA 172
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 252-332 9.40e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 9.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 252 YDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRANMIKEAEE 331
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 .
gi 568988475 332 M 332
Cdd:COG5010  144 A 144
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 7-156 1.93e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 1.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   7 QLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQVPPNkIAYEYSELLLYQNQvmreanlFQESLEHIETYEK 86
Cdd:COG2956  101 KLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH-AYCELAELYLEQGD-------YDEAIEALEKALK 172

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568988475  87 LICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKA-LQLRSLDERLQLYEEVSKQHP 156
Cdd:COG2956  173 LDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELyEKLGDPEEALELLRKALELDP 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
243-493 2.13e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 2.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 243 WVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLR 322
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 323 ANMIKEAEEMCSRFTREGTSAMENLNEMQCmwfetecisAYQRLGRYGDALKKCHEVerhfLEITDDqfDFHTYCMRKmt 402
Cdd:COG0457   89 LGRYEEALEDYDKALELDPDDAEALYNLGL---------ALLELGRYDEAIEAYERA----LELDPD--DADALYNLG-- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 403 lRAYVGLLRLEDALRrhtfYFKAARSAIEIYLKLHDNPLTNDSKQQDIDSENLSAKEMKKMLSKQRRAQKKAKVEEERKH 482
Cdd:COG0457  152 -IALEKLGRYEEALE----LLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLA 226

                        250
                 ....*....|.
gi 568988475 483 TERERQQKNQK 493
Cdd:COG0457  227 LALLLALRLAA 237
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
242-335 2.95e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 2.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 242 IWVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYML 321
Cdd:COG0457   76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                         90
                 ....*....|....
gi 568988475 322 RANMIKEAEEMCSR 335
Cdd:COG0457  156 KLGRYEEALELLEK 169
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 244-419 3.19e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.18  E-value: 3.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 244 VQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRA 323
Cdd:COG2956  112 ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 324 NMIKEAEEMCSRFTREGTSAMENLNEMQcmwfeteciSAYQRLGRYGDALKKCHEVERHFLEITDDQFDFHTYCMRKMTL 403
Cdd:COG2956  192 GDYEEAIAALERALEQDPDYLPALPRLA---------ELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLE 262

                        170
                 ....*....|....*.
gi 568988475 404 RAyvgLLRLEDALRRH 419
Cdd:COG2956  263 AA---LALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 7-125 3.76e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 3.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   7 QLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQvppnkiayEYSELLLYQNQVMREANLFQESLEHIETYEK 86
Cdd:COG4783   29 KALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP--------DEPEARLNLGLALLKAGDYDEALALLEKALK 100

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 568988475  87 LICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAEN 125
Cdd:COG4783  101 LDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 244-331 6.63e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.06  E-value: 6.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 244 VQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRA 323
Cdd:COG3914  148 AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227


                 ....*...
gi 568988475 324 NMIKEAEE 331
Cdd:COG3914  228 CDWEVYDR 235
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 7-302 7.11e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 7.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   7 QLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEefrqtqqvppNKIAYEYSELLLYQN--QVMREANLFQESLEHIETY 84
Cdd:COG2956   33 EALELDPETVEAHLALGNLYRRRGEYDRAIRIHQ----------KLLERDPDRAEALLElaQDYLKAGLLDRAEELLEKL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475  85 EKLICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAEN-WCYYEGLEKALQLRSLDERLQLYEEVSKQHPRavsprr 163
Cdd:COG2956  103 LELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENaHAYCELAELYLEQGDYDEAIEALEKALKLDPD------ 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 164 lplsfapgkkfrelmdkflrpnfskgCPPLFTTLKSLYCDTEKVsiiQELVTNYEASLKMNGYFSPyengekeppttliw 243
Cdd:COG2956  177 --------------------------CARALLLLAELYLEQGDY---EEAIAALERALEQDPDYLP-------------- 213

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568988475 244 VQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMkAKIYKHMGNLKEAAQWMDEA 302
Cdd:COG2956  214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALALLERQ 271
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
7-158 1.14e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   7 QLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRqtqqvppnKIAYEYSELLLYQNQVMREANLFQESLEHIETYEK 86
Cdd:COG0457   33 KALELDPDDAEALYNLGLAYLRLGRYEEALADYEQAL--------ELDPDDAEALNNLGLALQALGRYEEALEDYDKALE 104

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568988475  87 LICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKAL-QLRSLDERLQLYEEVSKQHPRA 158
Cdd:COG0457  105 LDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALeKLGRYEEALELLEKLEAAALAA 177
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 7-155 1.78e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475   7 QLLQLRPTQRASWIGYAIAYHLLKDYDTALKLLEEFRQTQQvppnkiayEYSELLLYQNQVMREANLFQESLEHIETYEK 86
Cdd:COG2956  135 RLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDP--------DCARALLLLAELYLEQGDYEEAIAALERALE 206

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568988475  87 LICDKLLVEEIKGEMLLKLGRLKEASEVFRNLIDWNAENWCYYEGLEKALQLRSLDERLQLYEEVSKQH 155
Cdd:COG2956  207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 243-306 6.10e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 6.10e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568988475 243 WVQYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLD 306
Cdd:COG4783   73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 245-438 6.67e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 6.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 245 QYFLAQHYDKLGQYFLALEYINAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLDTADRFINSKCAKYMLRAN 324
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568988475 325 MIKEAEEMCSRFTREGTSAMENLNEMqcmwfetecISAYQRLGRYGDALkkchEVERHFLEITDDQFDFH-----TYCMR 399
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLL---------AEIYEQEGDWEKAI----EVLERLLKLGPENAHAYcelaeLYLEQ 157

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 568988475 400 KMTLRAyvgLLRLEDALRRHTFYFKAARSAIEIYLKLHD 438
Cdd:COG2956  158 GDYDEA---IEALEKALKLDPDCARALLLLAELYLEQGD 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
242-306 9.54e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 9.54e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568988475 242 IWVQYFLAQHYDKLGQYFLALEYiNAVIASTPTLIELFYMKAKIYKHMGNLKEAAQWMDEAQSLD 306
Cdd:COG3063   26 ADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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