|
Name |
Accession |
Description |
Interval |
E-value |
| fadJ |
PRK11154 |
fatty acid oxidation complex subunit alpha FadJ; |
21-646 |
1.59e-118 |
|
fatty acid oxidation complex subunit alpha FadJ;
Pssm-ID: 236864 [Multi-domain] Cd Length: 708 Bit Score: 369.61 E-value: 1.59e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 21 LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIA--NAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGR 98
Cdd:PRK11154 93 LFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCtdDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGK 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 99 HISTDEALKLGILDVVVKSD-----PVEEAIKFAQTVIGKPIEPRRILNKPVpslpNMDSVFAEAIAKVRKQ----YPgr 169
Cdd:PRK11154 173 QLRAKQALKLGLVDDVVPHSillevAVELAKKGKPARRPLPVRERLLEGNPL----GRALLFKQARKKTLAKtqgnYP-- 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 170 lAPETCVRSVQASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFAEKSANKwstPSGASwktASAQPVSSVGVLGLGT 249
Cdd:PRK11154 247 -APERILDVVRTGLEKGMSSGYEAEARAFGELAMTPESAALRSIFFATTEMKK---DTGSD---AKPRPVNKVGVLGGGL 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 250 MGRGIA-ISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEA-SKSGQASAKPNL--RFSSST--KELSSVDLVIEAVFE 323
Cdd:PRK11154 320 MGGGIAyVTATKAGLPVRIKDINPQGINHALKYSWDLLDKKVkRRHLKPSERDKQmaLISGTTdyRGFKHADVVIEAVFE 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 324 DMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSK 403
Cdd:PRK11154 400 DLALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALAK 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 404 RIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSKPEDVDGVLEEFGFRMGPFRVSDLAGLDVGWKVrkgqgltGPSL 483
Cdd:PRK11154 480 KQGKTPIVVRDGAGFYVNRILAPYINEAARLLLEGEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKI-------IPIL 552
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 484 ppgtptRKRGNTRYSPIA--DMLCEAGRFGQKTGKGWYQYDKPLGRIHK-PDPwlseflSQYRETHHIKQRSISKEEILE 560
Cdd:PRK11154 553 ------EAALGERFSAPAafDKLLNDDRKGRKNGRGFYLYGQKGKKSKKqVDE------SVYPLLGITPQSRLSANEIAE 620
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 561 RCLYSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHVGGPMYYAASVGLPTVLEKLQKYYRQNPDipQLEPSDYLRRL 640
Cdd:PRK11154 621 RCVMLMLNEAVRCLDEGIIRSARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEVVAILERLAAQYGD--RFTPCERLVEM 698
|
....*.
gi 568996435 641 VAQGSP 646
Cdd:PRK11154 699 AERGES 704
|
|
| fadB |
PRK11730 |
fatty acid oxidation complex subunit alpha FadB; |
31-644 |
1.41e-117 |
|
fatty acid oxidation complex subunit alpha FadB;
Pssm-ID: 183293 [Multi-domain] Cd Length: 715 Bit Score: 367.27 E-value: 1.41e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 31 PVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGI 110
Cdd:PRK11730 104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGA 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 111 LDVVVKSDPVEE-AIKFAQTVIGKPIE---PRRILNKPVPsLPNMDSVFAEAIAKVR------KQYPgrlAPETCVRSVQ 180
Cdd:PRK11730 184 VDAVVAPEKLQEaALALLKQAIAGKLDwkaRRQPKLEPLK-LSKIEAMMSFTTAKGMvaqkagKHYP---APMTAVKTIE 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 181 ASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFAE----KSANKWStpsgaswktASAQPVSSVGVLGLGTMGRGIAI 256
Cdd:PRK11730 260 AAAGLGRDEALELEAKGFVKLAKTNVARALVGIFLNDqyvkGKAKKLA---------KDAKPVKQAAVLGAGIMGGGIAY 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 257 SFARVGIPVVAVESDPKQLD----TAKKIITSTLEK---EASKSGQ--ASAKPNLRFSsstkELSSVDLVIEAVFEDMNL 327
Cdd:PRK11730 331 QSASKGVPVIMKDINQKALDlgmtEAAKLLNKQVERgkiDGAKMAGvlSSIRPTLDYA----GFERVDVVVEAVVENPKV 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 328 KKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSKRIGK 407
Cdd:PRK11730 407 KAAVLAEVEQKVREDTILASNTSTISISLLAKALKRPENFCGMHFFNPVHRMPLVEVIRGEKTSDETIATVVAYASKMGK 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 408 IGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSKPEDVDGVLE-EFGFRMGPFRVSDLAGLDVGwkvRKGQGLtgpsLPPG 486
Cdd:PRK11730 487 TPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRQIDKVMEkQFGWPMGPAYLLDVVGIDTA---HHAQAV----MAEG 559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 487 TPTRKRGNTRySPIaDMLCEAGRFGQKTGKGWYQY--DKPlGRIHK-PDPWLSEFLsqyrETHHIKQRSISKEEILERCL 563
Cdd:PRK11730 560 FPDRMKKDYR-DAI-DVLFEAKRFGQKNGKGFYRYeeDKK-GKPKKeVDPAVYELL----APVVQPKREFSDEEIIARMM 632
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 564 YSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHVGGPMYYAASVGLPTVLEKLQKYYRQNpdiPQLEPSDYLRRLVAQ 643
Cdd:PRK11730 633 IPMINEVVRCLEEGIVASPAEADMALVYGLGFPPFRGGAFRYLDTLGVANYVALADKYAHLG---PLYQVPEGLREMAAN 709
|
.
gi 568996435 644 G 644
Cdd:PRK11730 710 G 710
|
|
| FadB |
COG1250 |
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ... |
238-521 |
6.14e-112 |
|
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440862 [Multi-domain] Cd Length: 281 Bit Score: 337.85 E-value: 6.14e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 238 PVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKSGQASAKP-----NLRFSSSTKELS 312
Cdd:COG1250 1 EIKKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEEEAdaalaRITPTTDLAALA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 313 SVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSP 392
Cdd:COG1250 81 DADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 393 TTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGS-KPEDVDGVLEE-FGFRMGPFRVSDLAGLDVGW 470
Cdd:COG1250 161 ETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYLNEAIRLLEEGVaSPEDIDAAMRLgFGFPMGPFELADLVGLDTAL 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 568996435 471 KVRKgqgltgpSLPPGTPTRKrgnTRYSPIADMLCEAGRFGQKTGKGWYQY 521
Cdd:COG1250 241 AVLE-------VLYEALGDPR---YRPPPLLKKLVEAGRLGRKTGRGFYDY 281
|
|
| fa_ox_alpha_mit |
TIGR02441 |
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ... |
3-621 |
1.87e-103 |
|
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).
Pssm-ID: 131494 [Multi-domain] Cd Length: 737 Bit Score: 331.03 E-value: 1.87e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIH---GFKSPTGLTLGS-----LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIA--NAKARVGFPEVMLGIL 72
Cdd:TIGR02441 74 AGADIQmiaACKTAQEVTQLSqegqeMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLL 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 73 PGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKS-----DPVEE---------AIKFAQTVIGKPIEPR 138
Cdd:TIGR02441 154 PGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVDPlgpglKPAEEntieyleevAVKFAQGLANGKLSIN 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 139 R------ILNKPVPSLPNM-DSVFAEAIAKVRKQ----YPgrlAPETCVRSVQASVKHPYEVAIKEEAKLFMYLRGSGQA 207
Cdd:TIGR02441 234 RdkglvhKITQYVMTNPFVrQQVYKTAEDKVMKQtkglYP---APLKILDVVRTGYDQGPDAGYEAESKAFGELSMTFES 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 208 RALQYAFFAEKSA--NKWSTPSgaswktasaQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITST 285
Cdd:TIGR02441 311 KALIGLFHGQTDCkkNKFGKPQ---------RPVKTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKG 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 286 LEKEASKSGQASAKPNLRFSSSTKEL-----SSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASS 360
Cdd:TIGR02441 382 LNKKVKRKKITSLERDSILSNLTPTLdysgfKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAV 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 361 TDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSK 440
Cdd:TIGR02441 462 SSRPEKVIGMHYFSPVDKMQLLEIITHDGTSKDTLASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQEGVD 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 441 PEDVDGVLEEFGFRMGPFRVSDLAGLDVGWKVRKGQGLT-GPSLPPGTPTrkrgntryspIADMLCEAGRFGQKTGKGWY 519
Cdd:TIGR02441 542 PKKLDKLTTKFGFPVGAATLADEVGVDVAEHVAEDLGKAfGERFGGGSAE----------LLSELVKAGFLGRKSGKGIF 611
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 520 QYDKPLGRIHKPDPWLSEFLSQYREThhIKQRSISKEEILERCLYSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHV 599
Cdd:TIGR02441 612 IYQEGKKGSKKVNSDADEILAQYKLP--PKAEVSSPEDIQIRLVSRFVNEAVLCLEEGILASPSEGDIGAVFGLGFPPFL 689
|
650 660
....*....|....*....|..
gi 568996435 600 GGPMYYAASVGLPTVLEKLQKY 621
Cdd:TIGR02441 690 GGPFRFVDLYGADKLVDKMEKY 711
|
|
| 3HCDH_N |
pfam02737 |
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ... |
241-415 |
2.50e-70 |
|
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.
Pssm-ID: 397037 [Multi-domain] Cd Length: 180 Bit Score: 226.27 E-value: 2.50e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 241 SVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASK-----SGQASAKPNLRFSSSTKELSSVD 315
Cdd:pfam02737 1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERLVEKgriteEEVDAALARISFTTDLAAAVDAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 316 LVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTI 395
Cdd:pfam02737 81 LVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTSPETV 160
|
170 180
....*....|....*....|
gi 568996435 396 ATVMSLSKRIGKIGVVVGNC 415
Cdd:pfam02737 161 ATTVELAKKIGKTPVVVKDT 180
|
|
| PLN02545 |
PLN02545 |
3-hydroxybutyryl-CoA dehydrogenase |
239-526 |
2.15e-68 |
|
3-hydroxybutyryl-CoA dehydrogenase
Pssm-ID: 215300 [Multi-domain] Cd Length: 295 Bit Score: 225.38 E-value: 2.15e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 239 VSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKS--GQASAKPNL---RFSSSTKELSS 313
Cdd:PLN02545 4 IKKVGVVGAGQMGSGIAQLAAAAGMDVWLLDSDPAALSRGLDSISSSLARLVKKGkmSQEEADATLgriRCTTNLEELRD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 314 VDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPT 393
Cdd:PLN02545 84 ADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEIIRGADTSDE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 394 TIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVD-GVLEEFGFRMGPFRVSDLAGLDVGWK 471
Cdd:PLN02545 164 VFDATKALAERFGKTVVCSQDYPGFIVNRILMPMINEAFYALYTGvASKEDIDtGMKLGTNHPMGPLHLADFIGLDTCLS 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 568996435 472 VRKG--QGLtgpslppgtptrkrGNTRYSPIADML--CEAGRFGQKTGKGWYQYDKPLG 526
Cdd:PLN02545 244 IMKVlhEGL--------------GDSKYRPCPLLVqyVDAGRLGRKSGRGVYHYDGKKR 288
|
|
| PRK05808 |
PRK05808 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
239-521 |
3.28e-62 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 180269 [Multi-domain] Cd Length: 282 Bit Score: 208.28 E-value: 3.28e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 239 VSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKSGQASAKPN-----LRFSSSTKELSS 313
Cdd:PRK05808 3 IQKIGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVKKGKMTEADKEaalarITGTTDLDDLKD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 314 VDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPT 393
Cdd:PRK05808 83 ADLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATSDA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 394 TIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLEeFGFR--MGPFRVSDLAGLDVGW 470
Cdd:PRK05808 163 THEAVEALAKKIGKTPVEVKNAPGFVVNRILIPMINEAIFVLAEGvATAEDIDEGMK-LGCNhpIGPLALADLIGLDTCL 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 568996435 471 KVRKgqgltgpSLPPGTptrkrGNTRYSPiADMLCE---AGRFGQKTGKGWYQY 521
Cdd:PRK05808 242 AIME-------VLYEGF-----GDSKYRP-CPLLRKmvaAGWLGRKTGRGFYDY 282
|
|
| PRK08268 |
PRK08268 |
3-hydroxy-acyl-CoA dehydrogenase; Validated |
238-521 |
4.03e-55 |
|
3-hydroxy-acyl-CoA dehydrogenase; Validated
Pssm-ID: 236211 [Multi-domain] Cd Length: 507 Bit Score: 195.84 E-value: 4.03e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 238 PVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASK----SGQA-SAKPNLRFSSSTKELS 312
Cdd:PRK08268 6 SIATVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLAKLVEKgkltAEQAdAALARLRPVEALADLA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 313 SVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSP 392
Cdd:PRK08268 86 DCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPERVAGLHFFNPVPLMKLVEVVSGLATDP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 393 TTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVL-EEFGFRMGPFRVSDLAGLDVGW 470
Cdd:PRK08268 166 AVADALYALARAWGKTPVRAKDTPGFIVNRAARPYYTEALRVLEEGvADPATIDAILrEAAGFRMGPFELMDLIGLDVNH 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 471 KVrkgqgltgpslppgtpTRK-----RGNTRY--SPIADMLCEAGRFGQKTGKGWYQY 521
Cdd:PRK08268 246 AV----------------MESvyrqfYQEPRFrpSLIQQELVAAGRLGRKSGQGFYRY 287
|
|
| PRK06130 |
PRK06130 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
238-521 |
1.50e-54 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 235707 [Multi-domain] Cd Length: 311 Bit Score: 188.83 E-value: 1.50e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 238 PVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKSGQASAKPNLRFSSSTKE-LSSVDL 316
Cdd:PRK06130 3 PIQNLAIIGAGTMGSGIAALFARKGLQVVLIDVMEGALERARGVIERALGVYAPLGIASAGMGRIRMEAGLAAaVSGADL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 317 VIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTTIA 396
Cdd:PRK06130 83 VIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGDKTSPQTVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 397 TVMSLSKRIGKIGVVVG-NCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLE-EFGFRM---GPFRVSDLAGLDVGW 470
Cdd:PRK06130 163 TTMALLRSIGKRPVLVKkDIPGFIANRIQHALAREAISLLEKGvASAEDIDEVVKwSLGIRLaltGPLEQRDMNGLDVHL 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 568996435 471 KVRK--GQGLTGPSLPpgtptrkrgntrySPIADMLCEAGRFGQKTGKGWYQY 521
Cdd:PRK06130 243 AVASylYQDLENRTTP-------------SPLLEEKVEAGELGAKSGQGFYAW 282
|
|
| PRK09260 |
PRK09260 |
3-hydroxyacyl-CoA dehydrogenase; |
239-522 |
7.61e-53 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 236434 [Multi-domain] Cd Length: 288 Bit Score: 183.45 E-value: 7.61e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 239 VSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASK-----SGQASAKPNLRFSSSTKE-LS 312
Cdd:PRK09260 1 IEKLVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQLESAQQEIASIFEQGVARgklteAARQAALARLSYSLDLKAaVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 313 SVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSP 392
Cdd:PRK09260 81 DADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETSD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 393 TTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLE-EFGFRMGPFRVSDLAGLDVGW 470
Cdd:PRK09260 161 ETVQVAKEVAEQMGKETVVVNEFPGFVTSRISALVGNEAFYMLQEGvATAEDIDKAIRlGLNFPMGPLELGDLVGLDTRL 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 568996435 471 KVRKGQGLT-GPSLPPgtptrkrgntrySPIADMLCEAGRFGQKTGKGWYQYD 522
Cdd:PRK09260 241 NNLKYLHETlGEKYRP------------APLLEKYVKAGRLGRKTGRGVYDYT 281
|
|
| PRK07819 |
PRK07819 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
235-521 |
3.64e-50 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181133 [Multi-domain] Cd Length: 286 Bit Score: 176.33 E-value: 3.64e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 235 SAQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKsGQAS------AKPNLRFSSST 308
Cdd:PRK07819 1 MSDAIQRVGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKSLERAVSR-GKLTererdaALARLRFTTDL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 309 KELSSVDLVIEAVFEDMNLKKKVFAELSALC-KPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPS 387
Cdd:PRK07819 80 GDFADRQLVIEAVVEDEAVKTEIFAELDKVVtDPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 388 RYSSPTTIATVMSL-SKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVD-GVLEEFGFRMGPFRVSDLA 464
Cdd:PRK07819 160 LVTSEATVARAEEFaSDVLGKQVVRAQDRSGFVVNALLVPYLLSAIRMVESGfATAEDIDkAMVLGCAHPMGPLRLSDLV 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568996435 465 GLDVgwkvrkgQGLTGPSL----------PPgtptrkrgntrysPIADMLCEAGRFGQKTGKGWYQY 521
Cdd:PRK07819 240 GLDT-------VKAIADSMyeefkeplyaPP-------------PLLLRMVEAGLLGKKSGRGFYTY 286
|
|
| PRK06035 |
PRK06035 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
239-467 |
1.51e-47 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 180361 [Multi-domain] Cd Length: 291 Bit Score: 169.29 E-value: 1.51e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 239 VSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITS-------TLEK-EASKSGQASAKPNLRFSSSTKE 310
Cdd:PRK06035 3 IKVIGVVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMELIESgpyglrnLVEKgKMSEDEAKAIMARIRTSTSYES 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 311 LSSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYS 390
Cdd:PRK06035 83 LSDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAALT 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568996435 391 SPTTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLE-EFGFRMGPFRVSDLAGLD 467
Cdd:PRK06035 163 SEETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGiATIKDIDEMCKlAFGFPMGPFELMDIIGID 241
|
|
| PRK07530 |
PRK07530 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
236-524 |
3.40e-42 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181018 [Multi-domain] Cd Length: 292 Bit Score: 154.40 E-value: 3.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 236 AQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASK---SGQASAKPNLRFSSST--KE 310
Cdd:PRK07530 1 MMAIKKVGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLARQVAKgkiSEEARAAALARISTATdlED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 311 LSSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYS 390
Cdd:PRK07530 81 LADCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRGIAT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 391 SPTTIATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLeEFG--FRMGPFRVSDLAGLD 467
Cdd:PRK07530 161 DEATFEAAKEFVTKLGKTITVAEDFPAFIVNRILLPMINEAIYTLYEGvGSVEAIDTAM-KLGanHPMGPLELADFIGLD 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 468 VGWKVRK--GQGLtgpslppgtptrkrGNTRYSPiadmlC-------EAGRFGQKTGKGWYQY--DKP 524
Cdd:PRK07530 240 TCLSIMQvlHDGL--------------ADSKYRP-----CpllvkyvEAGWLGRKTGRGFYDYrgEVP 288
|
|
| PRK08293 |
PRK08293 |
3-hydroxyacyl-CoA dehydrogenase; |
242-521 |
3.64e-33 |
|
3-hydroxyacyl-CoA dehydrogenase;
Pssm-ID: 181359 [Multi-domain] Cd Length: 287 Bit Score: 128.90 E-value: 3.64e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 242 VGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIIT-------STLEkEASKSGQASAKPNLRFSSSTKE-LSS 313
Cdd:PRK08293 6 VTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAkladryvRDLE-ATKEAPAEAALNRITLTTDLAEaVKD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 314 VDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSpaHIMR--LLEVIPSRYSS 391
Cdd:PRK08293 85 ADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFAEATGRPEKFLALHFAN--EIWKnnTAEIMGHPGTD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 392 PTTIATVMSLSKRIGKIGVVVgncY----GFVGNRMLAPYYNQGYFLIEEG-SKPEDVD----GVLeefGFRMGPFRVSD 462
Cdd:PRK08293 163 PEVFDTVVAFAKAIGMVPIVL---KkeqpGYILNSLLVPFLSAALALWAKGvADPETIDktwmIAT---GAPMGPFGILD 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568996435 463 LAGLDVGWKVRKGQGltgpslppgtptRKRGNTRYSPIADMLCE---AGRFGQKTGKGWYQY 521
Cdd:PRK08293 237 IVGLDTAYNITSNWA------------EATDDENAKKAAALLKEyidKGKLGVATGEGFYNY 286
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
417-521 |
7.44e-30 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 113.08 E-value: 7.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 417 GFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLEE-FGFRMGPFRVSDLAGLDVGWKVRKGQGLtgpslppGTPTRKRgn 494
Cdd:pfam00725 1 GFVVNRLLAPYLNEAIRLVEEGvATPEDIDAAMRLgLGLPMGPFELSDLVGLDVGYHILEVLAE-------EFGDRAY-- 71
|
90 100
....*....|....*....|....*..
gi 568996435 495 tRYSPIADMLCEAGRFGQKTGKGWYQY 521
Cdd:pfam00725 72 -RPPPLLEKLVEAGRLGRKTGKGFYKY 97
|
|
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
238-463 |
3.06e-29 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 118.22 E-value: 3.06e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 238 PVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEASKSGQASAKPN-----LRFSSSTKE-L 311
Cdd:PRK06129 1 PMGSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDLAAFDLLDGEAPDavlarIRVTDSLADaV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 312 SSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALD----VDDIAsstDRPQLVIGtHFFSPAHIMRLLEVIPS 387
Cdd:PRK06129 81 ADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLasafTEHLA---GRERCLVA-HPINPPYLIPVVEVVPA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 388 RYSSPTTIATVMSLSKRIGKIGVVVG-NCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLEE-FGFR---MGPFRVS 461
Cdd:PRK06129 157 PWTAPATLARAEALYRAAGQSPVRLRrEIDGFVLNRLQGALLREAFRLVADGvASVDDIDAVIRDgLGLRwsfMGPFETI 236
|
..
gi 568996435 462 DL 463
Cdd:PRK06129 237 DL 238
|
|
| CaiD |
COG1024 |
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ... |
3-218 |
4.80e-28 |
|
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440647 [Multi-domain] Cd Length: 249 Bit Score: 113.34 E-value: 4.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSPTGL--------TLGSLVDEIQRYQKPVVAAIQGValggglelalgCHYRIANAKARVGFPEVMLGILPG 74
Cdd:COG1024 58 AGADLKELAAAADPeearafarGLQRLFRALRRLPKPVIAAVNGAalggglelalaCDLRIAAEDARFGLPEVRLGLIPG 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 75 ARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAqtvigkpiepRRILNKPVPSLpnmds 153
Cdd:COG1024 138 GGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVVPDDELlAAALALA----------ARLAAGPPLAL----- 202
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568996435 154 vfaeAIAKvrkqypgrlapetcvRSVQASVKHPYEVAIKEEAKLFMYLRGSGQARALQYAFFaEK 218
Cdd:COG1024 203 ----AATK---------------RALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL-EK 247
|
|
| PRK08269 |
PRK08269 |
3-hydroxybutyryl-CoA dehydrogenase; Validated |
250-522 |
6.29e-28 |
|
3-hydroxybutyryl-CoA dehydrogenase; Validated
Pssm-ID: 181340 [Multi-domain] Cd Length: 314 Bit Score: 114.77 E-value: 6.29e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 250 MGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTL-EKEASKSGQAS-------------AKPNLRFSSSTKE-LSSV 314
Cdd:PRK08269 1 MGQGIALAFAFAGHDVTLIDFKPRDAAGWRALDAEARaEIERTLAALVAlgridaaqadavlARIAVVARDGAADaLADA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 315 DLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPTT 394
Cdd:PRK08269 81 DLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDATDPAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 395 IATVMSLSKRIGKIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLEE-FGFR---MGPFRVSDLAGLDVG 469
Cdd:PRK08269 161 VDRLAALLERIGKVPVVCGPSPGYIVPRIQALAMNEAARMVEEGvASAEDIDKAIRTgFGLRfavLGLLEFIDWGGCDIL 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 568996435 470 WKV-RKGQGLTGPSlppgtptrkrgntRYSP--IADMLCEAGRFGQKTGKGWYQYD 522
Cdd:PRK08269 241 YYAsRYLAGEIGPD-------------RFAPpaIVVRNMEEGRDGLRTGAGFYDYA 283
|
|
| crotonase-like |
cd06558 |
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ... |
3-130 |
7.91e-25 |
|
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.
Pssm-ID: 119339 [Multi-domain] Cd Length: 195 Bit Score: 102.25 E-value: 7.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSPTG---------LTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILP 73
Cdd:cd06558 58 AGADLKELAALSDageearafiRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVP 137
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 74 GARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSD-PVEEAIKFAQTV 130
Cdd:cd06558 138 GGGGTQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVVPDEeLLAAALELARRL 195
|
|
| PRK07658 |
PRK07658 |
enoyl-CoA hydratase; Provisional |
4-198 |
5.86e-23 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 181070 [Multi-domain] Cd Length: 257 Bit Score: 98.55 E-value: 5.86e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 4 GADIHGFkspTGLTLGS-----------LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGIL 72
Cdd:PRK07658 61 GADIKEF---TSVTEAEqatelaqlgqvTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLI 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 73 PGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAQTVIGK-PIEPRRILnkpvpslpn 150
Cdd:PRK07658 138 PGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGLVNGVFPEETLlDDAKKLAKKIAGKsPATTRAVL--------- 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568996435 151 mdsvfaeaiakvrkqypgrlapetcvRSVQASVKHPYEVAIKEEAKLF 198
Cdd:PRK07658 209 --------------------------ELLQTTKSSSYYEGVKREAKIF 230
|
|
| PRK05809 |
PRK05809 |
short-chain-enoyl-CoA hydratase; |
3-135 |
7.16e-22 |
|
short-chain-enoyl-CoA hydratase;
Pssm-ID: 180270 [Multi-domain] Cd Length: 260 Bit Score: 95.58 E-value: 7.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSPTGL------TLGSLV-DEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGA 75
Cdd:PRK05809 64 AGADISEMKDLNEEegrkfgLLGNKVfRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGF 143
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568996435 76 RGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILD-VVVKSDPVEEAIKFAQTVIGK-PI 135
Cdd:PRK05809 144 GGTQRLARIVGPGKAKELIYTGDMINAEEALRIGLVNkVVEPEKLMEEAKALANKIAANaPI 205
|
|
| PRK07531 |
PRK07531 |
carnitine 3-dehydrogenase; |
238-483 |
7.02e-21 |
|
carnitine 3-dehydrogenase;
Pssm-ID: 236044 [Multi-domain] Cd Length: 495 Bit Score: 96.35 E-value: 7.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 238 PVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKqldtAKKIITSTL---EKEASKSGQASAKP--NLRFSSSTKE-L 311
Cdd:PRK07531 3 MIMKAACIGGGVIGGGWAARFLLAGIDVAVFDPHPE----AERIIGEVLanaERAYAMLTDAPLPPegRLTFCASLAEaV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 312 SSVDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSS 391
Cdd:PRK07531 79 AGADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVELVGGGKTS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 392 PTTIATVMSLSKRIGKIGVVVGN-CYGFVGNRMLAPYYNQGYFLIEEG-SKPEDVDGVLE-EFGFR---MGPFRVSDLAG 465
Cdd:PRK07531 159 PETIRRAKEILREIGMKPVHIAKeIDAFVGDRLLEALWREALWLVKDGiATTEEIDDVIRySFGLRwaqMGLFETYRIAG 238
|
250
....*....|....*...
gi 568996435 466 LDVGWKVRKGQglTGPSL 483
Cdd:PRK07531 239 GEAGMRHFLAQ--FGPCL 254
|
|
| PRK07657 |
PRK07657 |
enoyl-CoA hydratase; Provisional |
18-130 |
2.87e-18 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 181069 [Multi-domain] Cd Length: 260 Bit Score: 85.17 E-value: 2.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 18 LGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSG 97
Cdd:PRK07657 86 IRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTG 165
|
90 100 110
....*....|....*....|....*....|....
gi 568996435 98 RHISTDEALKLGILDVVVKSDPVEE-AIKFAQTV 130
Cdd:PRK07657 166 RRISAQEAKEIGLVEFVVPAHLLEEkAIEIAEKI 199
|
|
| PRK05862 |
PRK05862 |
enoyl-CoA hydratase; Provisional |
23-132 |
7.86e-17 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180295 [Multi-domain] Cd Length: 257 Bit Score: 80.86 E-value: 7.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 23 DEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHIST 102
Cdd:PRK05862 88 EKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDA 167
|
90 100 110
....*....|....*....|....*....|.
gi 568996435 103 DEALKLGILDVVVKSDP-VEEAIKFAQTVIG 132
Cdd:PRK05862 168 AEAERAGLVSRVVPADKlLDEALAAATTIAS 198
|
|
| ECH_1 |
pfam00378 |
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ... |
3-135 |
1.34e-16 |
|
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.
Pssm-ID: 395302 [Multi-domain] Cd Length: 251 Bit Score: 80.10 E-value: 1.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADI-------HGFKSPTGLTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGA 75
Cdd:pfam00378 55 AGADLkemygegPAHQALYRENVLDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGA 134
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568996435 76 RGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAQTVIGKPI 135
Cdd:pfam00378 135 GGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGLVDKVVPEDQLlDEARELAEKLAEKSP 195
|
|
| PRK08138 |
PRK08138 |
enoyl-CoA hydratase; Provisional |
3-134 |
4.98e-15 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236162 [Multi-domain] Cd Length: 261 Bit Score: 75.47 E-value: 4.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGF--KSPTGLTLGS---LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARG 77
Cdd:PRK08138 67 AGADIKEFatAGAIEMYLRHterYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGG 146
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 78 TQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAQTVIGKP 134
Cdd:PRK08138 147 TQRLVRAVGKFKAMRMALTGCMVPAPEALAIGLVSEVVEDEQTlPRALELAREIARMP 204
|
|
| PRK09674 |
PRK09674 |
enoyl-CoA hydratase-isomerase; Provisional |
25-130 |
5.87e-15 |
|
enoyl-CoA hydratase-isomerase; Provisional
Pssm-ID: 182026 [Multi-domain] Cd Length: 255 Bit Score: 75.19 E-value: 5.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDE 104
Cdd:PRK09674 88 LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQ 167
|
90 100
....*....|....*....|....*..
gi 568996435 105 ALKLGIL-DVVVKSDPVEEAIKFAQTV 130
Cdd:PRK09674 168 AQQAGLVsEVFPPELTLERALQLASKI 194
|
|
| PRK06688 |
PRK06688 |
enoyl-CoA hydratase; Provisional |
3-148 |
9.01e-15 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235852 [Multi-domain] Cd Length: 259 Bit Score: 74.52 E-value: 9.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGF--KSPTGLTLGSLVDEIQRY----QKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGAR 76
Cdd:PRK06688 64 AGGDIKDFpkAPPKPPDELAPVNRFLRAiaalPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAG 143
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568996435 77 GTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVksdPVEEAIKFAQTVIgkpiepRRILNKPVPSL 148
Cdd:PRK06688 144 GSALLPRLIGRARAAEMLLLGEPLSAEEALRIGLVNRVV---PAAELDAEADAQA------AKLAAGPASAL 206
|
|
| PLN02600 |
PLN02600 |
enoyl-CoA hydratase |
31-130 |
9.78e-15 |
|
enoyl-CoA hydratase
Pssm-ID: 178210 [Multi-domain] Cd Length: 251 Bit Score: 74.46 E-value: 9.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 31 PVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGI 110
Cdd:PLN02600 90 PTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGL 169
|
90 100
....*....|....*....|.
gi 568996435 111 LDVVVKS-DPVEEAIKFAQTV 130
Cdd:PLN02600 170 VNYCVPAgEAYEKALELAQEI 190
|
|
| PRK07066 |
PRK07066 |
L-carnitine dehydrogenase; |
239-483 |
5.02e-14 |
|
L-carnitine dehydrogenase;
Pssm-ID: 168796 [Multi-domain] Cd Length: 321 Bit Score: 73.72 E-value: 5.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 239 VSSVGVLGLGTMGRG-IAISFARvGIPVVAVESDP---KQLDTAKKIITSTLEKEASKSGQASAKpnLRFSSSTKE-LSS 313
Cdd:PRK07066 7 IKTFAAIGSGVIGSGwVARALAH-GLDVVAWDPAPgaeAALRANVANAWPALERQGLAPGASPAR--LRFVATIEAcVAD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 314 VDLVIEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPT 393
Cdd:PRK07066 84 ADFIQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLGGERTAPE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 394 TIATVMSLSKRIGKIGV-VVGNCYGFVGNRMLAPYYNQGYFLIEEG--SKPEDVDGVLEEFGFR---MGPFRVSDLAGLD 467
Cdd:PRK07066 164 AVDAAMGIYRALGMRPLhVRKEVPGFIADRLLEALWREALHLVNEGvaTTGEIDDAIRFGAGIRwsfMGTFLTYTLAGGD 243
|
250
....*....|....*.
gi 568996435 468 VGwkVRKGQGLTGPSL 483
Cdd:PRK07066 244 AG--MRHFMQQFGPAL 257
|
|
| PRK05980 |
PRK05980 |
crotonase/enoyl-CoA hydratase family protein; |
3-123 |
3.47e-13 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 180335 [Multi-domain] Cd Length: 260 Bit Score: 70.17 E-value: 3.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSP----TGLTLGSLVDEIQR-------YQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGI 71
Cdd:PRK05980 63 AGADIHEFSASvaagADVALRDFVRRGQAmtarleaFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGM 142
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 568996435 72 LPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEA 123
Cdd:PRK05980 143 PPTFGGTQRLPRLAGRKRALELLLTGDAFSAERALEIGLVNAVVPHEELLPA 194
|
|
| PRK06494 |
PRK06494 |
enoyl-CoA hydratase; Provisional |
30-131 |
2.85e-12 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180591 [Multi-domain] Cd Length: 259 Bit Score: 67.37 E-value: 2.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 30 KPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLG 109
Cdd:PRK06494 95 KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELG 174
|
90 100
....*....|....*....|...
gi 568996435 110 ILDVVVKSDPVEEAIK-FAQTVI 131
Cdd:PRK06494 175 FVNEVVPAGELLAAAErWADDIL 197
|
|
| PRK08260 |
PRK08260 |
enoyl-CoA hydratase; Provisional |
2-118 |
1.63e-11 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236206 [Multi-domain] Cd Length: 296 Bit Score: 65.41 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 2 PSGADIHGFKSPTGL--TLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQ 79
Cdd:PRK08260 84 EADEEDRADPSDDGVrdGGGRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSW 163
|
90 100 110
....*....|....*....|....*....|....*....
gi 568996435 80 LLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSD 118
Cdd:PRK08260 164 FLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPD 202
|
|
| PRK05869 |
PRK05869 |
enoyl-CoA hydratase; Validated |
22-157 |
5.70e-11 |
|
enoyl-CoA hydratase; Validated
Pssm-ID: 235632 [Multi-domain] Cd Length: 222 Bit Score: 62.93 E-value: 5.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 22 VDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHIS 101
Cdd:PRK05869 92 VDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFD 171
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568996435 102 TDEALKLGILDVVVKSDPV-EEAIKFAqtvigkpiepRRILNKPVPSLPNMDSVFAE 157
Cdd:PRK05869 172 AEEALALGLIDEMVAPDDVyDAAAAWA----------RRFLDGPPHALAAAKAGISD 218
|
|
| PRK09076 |
PRK09076 |
enoyl-CoA hydratase; Provisional |
25-130 |
1.25e-10 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236373 [Multi-domain] Cd Length: 258 Bit Score: 62.24 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDE 104
Cdd:PRK09076 91 LSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAAT 170
|
90 100
....*....|....*....|....*..
gi 568996435 105 ALKLGIL-DVVVKSDPVEEAIKFAQTV 130
Cdd:PRK09076 171 ALRIGLVeEVVEKGEAREAALALAQKV 197
|
|
| PRK09245 |
PRK09245 |
crotonase/enoyl-CoA hydratase family protein; |
3-134 |
1.09e-09 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181723 Cd Length: 266 Bit Score: 59.60 E-value: 1.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSPTGLTLGSLVDEIQRYQK--------------PVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVM 68
Cdd:PRK09245 63 SGGNVKDMRARVGAFGGSPADIRQGYRHgiqriplalynlevPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVK 142
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568996435 69 LGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDP-VEEAIKFAQTVIGKP 134
Cdd:PRK09245 143 LGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQlLPAARALAERIAANP 209
|
|
| PRK06190 |
PRK06190 |
enoyl-CoA hydratase; Provisional |
25-141 |
1.47e-09 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235733 Cd Length: 258 Bit Score: 59.22 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDE 104
Cdd:PRK06190 90 WPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAAD 169
|
90 100 110
....*....|....*....|....*....|....*...
gi 568996435 105 ALKLGIL-DVVVKSDPVEEAIKFAQTVIGKPIEPRRIL 141
Cdd:PRK06190 170 ALRAGLVtEVVPHDELLPRARRLAASIAGNNPAAVRAL 207
|
|
| PRK06127 |
PRK06127 |
enoyl-CoA hydratase; Provisional |
3-123 |
1.47e-09 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235705 Cd Length: 269 Bit Score: 59.33 E-value: 1.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGF----KSPTGLTLGSLVDEIQR-----YQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILP 73
Cdd:PRK06127 71 SGADISQFeesrSDAEAVAAYEQAVEAAQaaladYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGY 150
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 568996435 74 GARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEA 123
Cdd:PRK06127 151 GYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIGLVHRVTAADDLETA 200
|
|
| PRK03580 |
PRK03580 |
crotonobetainyl-CoA hydratase; |
8-123 |
5.13e-09 |
|
crotonobetainyl-CoA hydratase;
Pssm-ID: 179599 [Multi-domain] Cd Length: 261 Bit Score: 57.78 E-value: 5.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 8 HGFKSPTGLTlgslvdEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGV 87
Cdd:PRK03580 79 FGPGGFAGLT------EIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPP 152
|
90 100 110
....*....|....*....|....*....|....*.
gi 568996435 88 PVALDLITSGRHISTDEALKLGILDVVVKSDPVEEA 123
Cdd:PRK03580 153 AIANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDR 188
|
|
| PRK07799 |
PRK07799 |
crotonase/enoyl-CoA hydratase family protein; |
27-130 |
7.65e-09 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181122 [Multi-domain] Cd Length: 263 Bit Score: 57.03 E-value: 7.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 27 RYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEAL 106
Cdd:PRK07799 98 RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAK 177
|
90 100
....*....|....*....|....*
gi 568996435 107 KLGILDVVVKSD-PVEEAIKFAQTV 130
Cdd:PRK07799 178 EIGLIGHVVPDGqALDKALELAELI 202
|
|
| PRK06210 |
PRK06210 |
enoyl-CoA hydratase; Provisional |
30-128 |
1.11e-08 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180472 Cd Length: 272 Bit Score: 56.64 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 30 KPVVAAIQGVALGGGLELALGCHYRIANAKAR--VGFPEVML----GIlpgargTQLLPRVVGVPVALDLITSGRHISTD 103
Cdd:PRK06210 109 KPVIAAINGACAGIGLTHALMCDVRFAADGAKftTAFARRGLiaehGI------SWILPRLVGHANALDLLLSARTFYAE 182
|
90 100
....*....|....*....|....*.
gi 568996435 104 EALKLGILDVVVKSDPV-EEAIKFAQ 128
Cdd:PRK06210 183 EALRLGLVNRVVPPDELmERTLAYAE 208
|
|
| PRK08150 |
PRK08150 |
crotonase/enoyl-CoA hydratase family protein; |
23-159 |
2.83e-08 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181254 Cd Length: 255 Bit Score: 55.41 E-value: 2.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 23 DEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHIST 102
Cdd:PRK08150 86 DKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDA 165
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568996435 103 DEALKLGILDVVV-KSDPVEEAIKFAQTVIGK-PIEPRRILNKpVPSLPNM---DSVFAEAI 159
Cdd:PRK08150 166 QEGERLGLAQYLVpAGEALDKAMELARRIAQNaPLTNFAVLNA-LPRIADMsadDGLFVESL 226
|
|
| 3HCDH |
pfam00725 |
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ... |
558-649 |
3.33e-08 |
|
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.
Pssm-ID: 395588 [Multi-domain] Cd Length: 97 Bit Score: 51.45 E-value: 3.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 558 ILERCLYSLINEAFRILEEGmAASPEHIDVIYLHGYGWPRhvgGPMYYAASVGLPTVLEKLQKYYRQNPDiPQLEPSDYL 637
Cdd:pfam00725 3 VVNRLLAPYLNEAIRLVEEG-VATPEDIDAAMRLGLGLPM---GPFELSDLVGLDVGYHILEVLAEEFGD-RAYRPPPLL 77
|
90
....*....|..
gi 568996435 638 RRLVAQGSPPLK 649
Cdd:pfam00725 78 EKLVEAGRLGRK 89
|
|
| PRK07659 |
PRK07659 |
enoyl-CoA hydratase; Provisional |
28-164 |
7.04e-08 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236073 [Multi-domain] Cd Length: 260 Bit Score: 54.27 E-value: 7.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 28 YQKP--VVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEA 105
Cdd:PRK07659 95 YTMPklTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEA 174
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568996435 106 LKLGILDVVVKSDPVEEAIKFAQTVIGKP----IEPRRILNK-PVPSLPNMDSVFAEAIAKVRK 164
Cdd:PRK07659 175 LDLGLIDEVIGGDFQTAAKQKISEWLQKPlkamIETKQIYCElNRSQLEQVLQLEKRAQYAMRQ 238
|
|
| PRK08258 |
PRK08258 |
enoyl-CoA hydratase family protein; |
3-128 |
8.16e-08 |
|
enoyl-CoA hydratase family protein;
Pssm-ID: 181329 Cd Length: 277 Bit Score: 54.20 E-value: 8.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGFKSP------------TGLTlGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLG 70
Cdd:PRK08258 76 SGGDVHEIIGPltkmdmpellafTRMT-GDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVG 154
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568996435 71 iLPGAR--GTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAQ 128
Cdd:PRK08258 155 -LAGADmgACALLPRIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELlAEAQALAR 214
|
|
| PRK07509 |
PRK07509 |
crotonase/enoyl-CoA hydratase family protein; |
31-133 |
8.19e-08 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181008 [Multi-domain] Cd Length: 262 Bit Score: 54.12 E-value: 8.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 31 PVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGI 110
Cdd:PRK07509 104 PVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAEEALELGL 183
|
90 100
....*....|....*....|...
gi 568996435 111 LDVVVkSDPVEEAIKFAQTVIGK 133
Cdd:PRK07509 184 VTHVS-DDPLAAALALAREIAQR 205
|
|
| PRK08259 |
PRK08259 |
crotonase/enoyl-CoA hydratase family protein; |
30-128 |
7.54e-07 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 236205 Cd Length: 254 Bit Score: 51.05 E-value: 7.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 30 KPVVAAIQGVALGGGLELALGCHYRIANAKA-------RVGFPevmlgILPGarGTQLLPRVVGVPVALDLITSGRHIST 102
Cdd:PRK08259 94 KPVIAAVSGYAVAGGLELALWCDLRVAEEDAvfgvfcrRWGVP-----LIDG--GTVRLPRLIGHSRAMDLILTGRPVDA 166
|
90 100
....*....|....*....|....*..
gi 568996435 103 DEALKLGILD-VVVKSDPVEEAIKFAQ 128
Cdd:PRK08259 167 DEALAIGLANrVVPKGQARAAAEELAA 193
|
|
| PRK06143 |
PRK06143 |
enoyl-CoA hydratase; Provisional |
18-124 |
8.22e-07 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180423 Cd Length: 256 Bit Score: 50.80 E-value: 8.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 18 LGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGIlPGARGTQLLPRVVGVPVALDLITSG 97
Cdd:PRK06143 89 LRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWARTRWLLLTG 167
|
90 100
....*....|....*....|....*..
gi 568996435 98 RHISTDEALKLGILDVVVKSDPVEEAI 124
Cdd:PRK06143 168 ETIDAAQALAWGLVDRVVPLAELDAAV 194
|
|
| PRK08252 |
PRK08252 |
crotonase/enoyl-CoA hydratase family protein; |
3-130 |
8.48e-07 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 181325 [Multi-domain] Cd Length: 254 Bit Score: 50.76 E-value: 8.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIHGF---KSPT--GLTLGSLVDeiQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARG 77
Cdd:PRK08252 62 AGMDLKAFargERPSipGRGFGGLTE--RPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGG 139
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 568996435 78 TQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKS-DPVEEAIKFAQTV 130
Cdd:PRK08252 140 LLRLPRRIPYHIAMELALTGDMLTAERAHELGLVNRLTEPgQALDAALELAERI 193
|
|
| PRK06023 |
PRK06023 |
crotonase/enoyl-CoA hydratase family protein; |
18-140 |
1.81e-06 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 168351 Cd Length: 251 Bit Score: 49.79 E-value: 1.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 18 LGSLVdeiqRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSG 97
Cdd:PRK06023 90 LIALA----EAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALG 165
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 568996435 98 RHISTDEALKLGILDVVVKSDPVE-EAIKFAQTVIGKPIEPRRI 140
Cdd:PRK06023 166 EGFSAEAAQEAGLIWKIVDEEAVEaETLKAAEELAAKPPQALQI 209
|
|
| PRK07468 |
PRK07468 |
crotonase/enoyl-CoA hydratase family protein; |
30-124 |
2.62e-06 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 180987 [Multi-domain] Cd Length: 262 Bit Score: 49.29 E-value: 2.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 30 KPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRvVGVPVALDLITSGRHISTDEALKLG 109
Cdd:PRK07468 101 KPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSARLFDAEEAVRLG 179
|
90
....*....|....*
gi 568996435 110 ILDVVVKSDPVEEAI 124
Cdd:PRK07468 180 LLSRVVPAERLDAAV 194
|
|
| PLN02664 |
PLN02664 |
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase |
25-133 |
2.63e-06 |
|
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
Pssm-ID: 178269 [Multi-domain] Cd Length: 275 Bit Score: 49.52 E-value: 2.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDE 104
Cdd:PLN02664 107 IEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRRFSGSE 186
|
90 100 110
....*....|....*....|....*....|.
gi 568996435 105 ALKLGILDVVVKS-DPVEEAIKF-AQTVIGK 133
Cdd:PLN02664 187 AKELGLVSRVFGSkEDLDEGVRLiAEGIAAK 217
|
|
| PRK08788 |
PRK08788 |
enoyl-CoA hydratase; Validated |
33-125 |
6.91e-06 |
|
enoyl-CoA hydratase; Validated
Pssm-ID: 236338 Cd Length: 287 Bit Score: 48.37 E-value: 6.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 33 VAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILD 112
Cdd:PRK08788 125 IALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVD 204
|
90
....*....|...
gi 568996435 113 VVVKSDPVEEAIK 125
Cdd:PRK08788 205 VLVEDGQGEAAVR 217
|
|
| PRK06144 |
PRK06144 |
enoyl-CoA hydratase; Provisional |
3-123 |
8.51e-06 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180424 [Multi-domain] Cd Length: 262 Bit Score: 47.68 E-value: 8.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADI---HGFKSP-TGLTLGSLVDE----IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEV-MLGILP 73
Cdd:PRK06144 68 AGTDIaqfRAFSTAeDAVAYERRIDRvlgaLEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPIArTLGNCL 147
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 568996435 74 GARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEEA 123
Cdd:PRK06144 148 SMSNLARLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDAR 197
|
|
| PRK06142 |
PRK06142 |
crotonase/enoyl-CoA hydratase family protein; |
21-134 |
9.14e-06 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 235714 Cd Length: 272 Bit Score: 47.66 E-value: 9.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 21 LVDEIQRYQ----------KPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVA 90
Cdd:PRK06142 91 LRREILRLQaainavadcrKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHL 170
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 568996435 91 LDLITSGRHISTDEALKLGILDVVVkSDP---VEEAIKFAQTVIGKP 134
Cdd:PRK06142 171 RELALTGRDIDAAEAEKIGLVNRVY-DDAdalLAAAHATAREIAAKS 216
|
|
| PLN03214 |
PLN03214 |
probable enoyl-CoA hydratase/isomerase; Provisional |
33-138 |
1.85e-05 |
|
probable enoyl-CoA hydratase/isomerase; Provisional
Pssm-ID: 215635 Cd Length: 278 Bit Score: 46.80 E-value: 1.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 33 VAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGI-LPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGIL 111
Cdd:PLN03214 111 VCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLI 190
|
90 100
....*....|....*....|....*...
gi 568996435 112 DVVVKSDP-VEEAIKFAQTVIGKPIEPR 138
Cdd:PLN03214 191 DEVVPAAAlMEAAASAMERALKLPSAAR 218
|
|
| ECH_2 |
pfam16113 |
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ... |
25-162 |
2.37e-05 |
|
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.
Pssm-ID: 465024 [Multi-domain] Cd Length: 331 Bit Score: 47.08 E-value: 2.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQG----------ValggglelalGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRV---VGVPVAL 91
Cdd:pfam16113 84 IATYPKPYVALMDGivmgggvglsV----------HGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLpgeLGLYLAL 153
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568996435 92 dlitSGRHISTDEALKLGILDVVVKS---DPVEEAIkfAQTVIGKPIEPRRILNKPVPSLPNMDSVFA---EAIAKV 162
Cdd:pfam16113 154 ----TGARLNGADALAAGLATHYVPSarlPALEEAL--AALDWSDPADVDAVLAEFAEESDPPPSPLAahrEAIDRC 224
|
|
| PRK07260 |
PRK07260 |
enoyl-CoA hydratase; Provisional |
20-123 |
2.55e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180910 [Multi-domain] Cd Length: 255 Bit Score: 46.27 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 20 SLVDEI----QRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLIT 95
Cdd:PRK07260 85 ELVNEIsfaiKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAM 164
|
90 100
....*....|....*....|....*...
gi 568996435 96 SGRHISTDEALKLGILDVVVKSDPVEEA 123
Cdd:PRK07260 165 TGEALTAEKALEYGFVYRVAESEKLEKT 192
|
|
| PRK05864 |
PRK05864 |
enoyl-CoA hydratase; Provisional |
3-118 |
6.12e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 168278 [Multi-domain] Cd Length: 276 Bit Score: 45.21 E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGAD---------IHGFKSPT-GLTLGSLVDEI----QRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVM 68
Cdd:PRK05864 69 SGADhksagvvphVEGLTRPTyALRSMELLDDVilalRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGIN 148
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 568996435 69 LGILPGARG-TQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSD 118
Cdd:PRK05864 149 NGLTASELGlSYLLPRAIGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDE 199
|
|
| PRK05995 |
PRK05995 |
enoyl-CoA hydratase; Provisional |
16-124 |
6.50e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 235664 [Multi-domain] Cd Length: 262 Bit Score: 44.92 E-value: 6.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 16 LTLGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPgargTQLLP---RVVGVPVALD 92
Cdd:PRK05995 86 RRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARR 161
|
90 100 110
....*....|....*....|....*....|..
gi 568996435 93 LITSGRHISTDEALKLGILDVVVKSDPVEEAI 124
Cdd:PRK05995 162 YFLTAERFDAAEALRLGLVHEVVPAEALDAKV 193
|
|
| PRK06563 |
PRK06563 |
crotonase/enoyl-CoA hydratase family protein; |
26-130 |
6.70e-05 |
|
crotonase/enoyl-CoA hydratase family protein;
Pssm-ID: 180625 [Multi-domain] Cd Length: 255 Bit Score: 44.95 E-value: 6.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 26 QRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEA 105
Cdd:PRK06563 89 RRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEA 168
|
90 100
....*....|....*....|....*.
gi 568996435 106 LKLGIL-DVVVKSDPVEEAIKFAQTV 130
Cdd:PRK06563 169 LRLGLVqEVVPPGEQLERAIELAERI 194
|
|
| PRK05870 |
PRK05870 |
enoyl-CoA hydratase; Provisional |
31-136 |
7.54e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 180298 Cd Length: 249 Bit Score: 44.72 E-value: 7.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 31 PVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGI 110
Cdd:PRK05870 97 PTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGL 176
|
90 100
....*....|....*....|....*..
gi 568996435 111 -LDVVvkSDPVEEAIKFAQTVIGKPIE 136
Cdd:PRK05870 177 aLMVA--DDPVAAALELAAGPAAAPRE 201
|
|
| PRK08139 |
PRK08139 |
enoyl-CoA hydratase; Validated |
25-134 |
8.24e-05 |
|
enoyl-CoA hydratase; Validated
Pssm-ID: 181249 Cd Length: 266 Bit Score: 44.93 E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGIL---PGARgtqlLPRVVGVPVALDLITSGRHIS 101
Cdd:PRK08139 100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLLTGEFID 175
|
90 100 110
....*....|....*....|....*....|....
gi 568996435 102 TDEALKLGILDVVVKSDPVEEAI-KFAQTVIGKP 134
Cdd:PRK08139 176 AATAREWGLVNRVVPADALDAAVaRLAAVIAAKS 209
|
|
| PRK06072 |
PRK06072 |
enoyl-CoA hydratase; Provisional |
4-143 |
8.80e-05 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 168377 [Multi-domain] Cd Length: 248 Bit Score: 44.77 E-value: 8.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 4 GADIHGFKSPTGLTLGS----LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQ 79
Cdd:PRK06072 60 GADLSEFAPDFAIDLREtfypIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAY 139
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 80 LLPRVVGVPvALDLITSGRHISTDEALKLGILDVVvkSDPVEEAIKFAQTVIGKP----IEPRRILNK 143
Cdd:PRK06072 140 FLLKLTGQR-FYEILVLGGEFTAEEAERWGLLKIS--EDPLSDAEEMANRISNGPfqsyIAAKRMINL 204
|
|
| PRK06495 |
PRK06495 |
enoyl-CoA hydratase/isomerase family protein; |
30-140 |
3.31e-04 |
|
enoyl-CoA hydratase/isomerase family protein;
Pssm-ID: 168580 [Multi-domain] Cd Length: 257 Bit Score: 42.76 E-value: 3.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 30 KPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQllpRVVGVPVALDLITSGRHISTDEALKLG 109
Cdd:PRK06495 98 KPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGGKHAM---RLFGHSLTRRMMLTGYRVPAAELYRRG 174
|
90 100 110
....*....|....*....|....*....|...
gi 568996435 110 ILDVVVKSDP-VEEAIKFAQTVIGK-PIEPRRI 140
Cdd:PRK06495 175 VIEACLPPEElMPEAMEIAREIASKsPLATRLA 207
|
|
| PRK11423 |
PRK11423 |
methylmalonyl-CoA decarboxylase; Provisional |
3-165 |
3.51e-04 |
|
methylmalonyl-CoA decarboxylase; Provisional
Pssm-ID: 236908 [Multi-domain] Cd Length: 261 Bit Score: 42.71 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 3 SGADIH----GFKSPTGLT--LGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGAR 76
Cdd:PRK11423 64 AGHDIHelpsGGRDPLSYDdpLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 77 GTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPVEE-AIKFAQTVIGK-PI------EPRRILNKPVPSL 148
Cdd:PRK11423 144 GILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDfTLQMAHHISEKaPLaiavikEQLRVLGEAHPMN 223
|
170
....*....|....*..
gi 568996435 149 PNMdsvFaEAIAKVRKQ 165
Cdd:PRK11423 224 PDE---F-ERIQGLRRA 236
|
|
| PRK05617 |
PRK05617 |
3-hydroxyisobutyryl-CoA hydrolase; Provisional |
25-134 |
2.44e-03 |
|
3-hydroxyisobutyryl-CoA hydrolase; Provisional
Pssm-ID: 235533 [Multi-domain] Cd Length: 342 Bit Score: 40.57 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 25 IQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGARGTQLLPRV---VGVPVALdlitSGRHIS 101
Cdd:PRK05617 96 IARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRApgaLGTYLAL----TGARIS 171
|
90 100 110
....*....|....*....|....*....|...
gi 568996435 102 TDEALKLGILDVVVKSDPVEEaikFAQTVIGKP 134
Cdd:PRK05617 172 AADALYAGLADHFVPSADLPA---LLDALISLR 201
|
|
| PLN02740 |
PLN02740 |
Alcohol dehydrogenase-like |
224-279 |
2.59e-03 |
|
Alcohol dehydrogenase-like
Pssm-ID: 178341 [Multi-domain] Cd Length: 381 Bit Score: 40.55 E-value: 2.59e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 568996435 224 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAI-SFARVGIPVVAVESDPKQLDTAK 279
Cdd:PLN02740 184 STGVGAAWNTANVQAGSSVAIFGLGAVGLAVAEgARARGASKIIGVDINPEKFEKGK 240
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
244-291 |
3.57e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 40.05 E-value: 3.57e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 568996435 244 VLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKIITSTLEKEAS 291
Cdd:COG0569 100 IIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEEDVLVIVGDAT 147
|
|
| PRK05981 |
PRK05981 |
enoyl-CoA hydratase/isomerase; |
1-134 |
4.55e-03 |
|
enoyl-CoA hydratase/isomerase;
Pssm-ID: 235661 Cd Length: 266 Bit Score: 39.33 E-value: 4.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 1 MPSGADIHGFKSPTGLTLGS----LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGILPGAR 76
Cdd:PRK05981 71 RGSGGRESDSGGDAGAALETayhpFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGG 150
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 568996435 77 GTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-EEAIKFAQTVIGKP 134
Cdd:PRK05981 151 STWLLPRLVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELmAEAMKLAHELANGP 209
|
|
| PRK08140 |
PRK08140 |
enoyl-CoA hydratase; Provisional |
21-110 |
5.78e-03 |
|
enoyl-CoA hydratase; Provisional
Pssm-ID: 236163 Cd Length: 262 Bit Score: 39.13 E-value: 5.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 21 LVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIA--NAKARVGFpeVMLGILPGARGTQLLPRVVGVPVALDLITSGR 98
Cdd:PRK08140 91 LVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAarSASFIQAF--VKIGLVPDSGGTWFLPRLVGMARALGLALLGE 168
|
90
....*....|..
gi 568996435 99 HISTDEALKLGI 110
Cdd:PRK08140 169 KLSAEQAEQWGL 180
|
|
| AdhP |
COG1064 |
D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family [Carbohydrate transport ... |
232-321 |
7.01e-03 |
|
D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family [Carbohydrate transport and metabolism];
Pssm-ID: 440684 [Multi-domain] Cd Length: 332 Bit Score: 38.94 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 232 KTASAQPVSSVGVLGLGTMGRgIAISFARV-GIPVVAVESDPKQLDTAKK-----IITSTlEKEASKsgqasakpnlrfs 305
Cdd:COG1064 156 RRAGVGPGDRVAVIGAGGLGH-LAVQIAKAlGAEVIAVDRSPEKLELARElgadhVVNSS-DEDPVE------------- 220
|
90
....*....|....*.
gi 568996435 306 sSTKELSSVDLVIEAV 321
Cdd:COG1064 221 -AVRELTGADVVIDTV 235
|
|
| MDR |
cd05188 |
Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; ... |
232-383 |
7.44e-03 |
|
Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; The medium chain reductase/dehydrogenases (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH) , quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines. Other MDR members have only a catalytic zinc, and some contain no coordinated zinc.
Pssm-ID: 176178 [Multi-domain] Cd Length: 271 Bit Score: 38.84 E-value: 7.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568996435 232 KTASAQPVSSVGVLGLGTMGRGIAISFARVGIPVVAVESDPKQLDTAKKI-ITSTLEkeasksgqaSAKPNLRFSSSTKE 310
Cdd:cd05188 128 RAGVLKPGDTVLVLGAGGVGLLAAQLAKAAGARVIVTDRSDEKLELAKELgADHVID---------YKEEDLEEELRLTG 198
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568996435 311 LSSVDLVIEAVFedmnlKKKVFAELSALCKPGAFLCT--NTSALDVDDIASSTDRPQL-VIGTHFFSPAHIMRLLE 383
Cdd:cd05188 199 GGGADVVIDAVG-----GPETLAQALRLLRPGGRIVVvgGTSGGPPLDDLRRLLFKELtIIGSTGGTREDFEEALD 269
|
|
| alcohol_DH_class_III |
cd08300 |
class III alcohol dehydrogenases; Members identified as glutathione-dependent formaldehyde ... |
224-280 |
9.08e-03 |
|
class III alcohol dehydrogenases; Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.
Pssm-ID: 176260 [Multi-domain] Cd Length: 368 Bit Score: 38.75 E-value: 9.08e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 568996435 224 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGIP-VVAVESDPKQLDTAKK 280
Cdd:cd08300 172 TTGYGAVLNTAKVEPGSTVAVFGLGAVGLAVIQGAKAAGASrIIGIDINPDKFELAKK 229
|
|
| |
