|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
487-677 |
3.60e-20 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 97.06 E-value: 3.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 487 PKGTPSQVTPPQGTPsqgTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTP 566
Cdd:PHA03378 645 VLVFPTPHQPPQVEI---TPYKPTWTQIGHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAAT 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 567 SEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQgtPSEGTPSQETLPRETPSEGTP 646
Cdd:PHA03378 722 GRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQP--PPQAPPAPQQRPRGAPTPQPP 799
|
170 180 190
....*....|....*....|....*....|.
gi 569008203 647 PQGTPSEGTPSQETVPQETPPQKLSFQDILT 677
Cdd:PHA03378 800 PQAGPTSMQLMPRAAPGQQGPTKQILRQLLT 830
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
454-676 |
6.70e-20 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 96.29 E-value: 6.70e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 454 EIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGT-------PSQGTPSEGTSLQ-------VSPSEV 519
Cdd:PHA03378 573 QIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSaprqwpmPLRPIPMRPLRMQpitfnvlVFPTPH 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 520 TPPQGTPSEVT------------PSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPS 587
Cdd:PHA03378 653 QPPQVEITPYKptwtqighipyqPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPG 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 588 EGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQE----TLPRETPSEGTPPQGTPSEGTPSQETVPQ 663
Cdd:PHA03378 733 RARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPpqapPAPQQRPRGAPTPQPPPQAGPTSMQLMPR 812
|
250
....*....|...
gi 569008203 664 ETPPQKLSFQDIL 676
Cdd:PHA03378 813 AAPGQQGPTKQIL 825
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
404-666 |
7.18e-18 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 89.74 E-value: 7.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 404 ESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQETPSQGTLSQESPSQ--WTLSKGTP 481
Cdd:PHA03378 594 QTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKptWTQIGHIP 673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 482 SQgTSPKGtPSQVTPPQGTPSQGTPSEGtslqvSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTP 561
Cdd:PHA03378 674 YQ-PSPTG-ANTMLPIQWAPGTMQPPPR-----APTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARP 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 562 PQGTPSEGTSPQGTPSEETPPQGTPSEGT---LPQGTPSQGTPPQGTPSEGTPPQGTPS--QGTPPQGTPSEGTPSQ--E 634
Cdd:PHA03378 747 PAAAPGRARPPAAAPGRARPPAAAPGAPTpqpPPQAPPAPQQRPRGAPTPQPPPQAGPTsmQLMPRAAPGQQGPTKQilR 826
|
250 260 270
....*....|....*....|....*....|..
gi 569008203 635 TLPRETPSEGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PHA03378 827 QLLTGGVKRGRPSLKKPAALERQAAAGPTPSP 858
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
401-653 |
2.31e-16 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 84.73 E-value: 2.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 401 QSQESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIK--DTSPQGTPYQYILT----KEIPFQETPSQGTLS---QESP 471
Cdd:PHA03378 612 QSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPtpHQPPQVEITPYKPTwtqiGHIPYQPSPTGANTMlpiQWAP 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 472 SQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTslqvsPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTP 551
Cdd:PHA03378 692 GTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAA-----PGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARP 766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 552 PQGTP---SEMTPPQGTPSEGTSPQGTPSEETPPQGTPsegtlpqgTPSQGTPPQGTPSEGTPPQ-------GTPSQGTP 621
Cdd:PHA03378 767 PAAAPgapTPQPPPQAPPAPQQRPRGAPTPQPPPQAGP--------TSMQLMPRAAPGQQGPTKQilrqlltGGVKRGRP 838
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 569008203 622 PQGTPSEGTPSQETLPRETPSEGT-----------PPQGTPSE 653
Cdd:PHA03378 839 SLKKPAALERQAAAGPTPSPGSGTsdkivqapvfyPPVLQPIQ 881
|
|
| CD20 |
pfam04103 |
CD20-like family; This family includes the CD20 protein and the beta subunit of the high ... |
44-137 |
3.02e-16 |
|
CD20-like family; This family includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc. The high affinity receptor for IgE is a tetrameric structure consisting of a single IgE-binding alpha subunit, a single beta subunit, and two disulfide-linked gamma subunits. The alpha subunit of Fc epsilon RI and most Fc receptors are homologous members of the Ig superfamily. By contrast, the beta and gamma subunits from Fc epsilon RI are not homologous to the Ig superfamily. Both molecules have four putative transmembrane segments and a probably topology where both amino- and carboxy termini protrude into the cytoplasm. This family also includes LR8 like proteins from humans, mice and rats. The function of the human LR8 protein is unknown although it is known to be strongly expressed in the lung fibroblasts. This family also includes sarcospan is a transmembrane component of dystrophin-associated glycoprotein. Loss of the sarcoglycan complex and sarcospan alone is sufficient to cause muscular dystrophy. The role of the sarcoglycan complex and sarcospan is thought to be to strengthen the dystrophin axis connecting the basement membrane with the cytoskeleton.
Pssm-ID: 461174 Cd Length: 155 Bit Score: 77.30 E-value: 3.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 44 LLGAIQILLSLVIVGFGNILALnftfsskeFPLVILT-GYPFWGAVIFLLTGLVTMSHDK-PRRILKQGVTTMNVLSSLT 121
Cdd:pfam04103 1 VLGVVQILLGLLSIVLGFILYS--------VSSSLLAsGYPFWGGIIFIISGVLGIAAEKrSTKLLVLLSLLLNLLSLFT 72
|
90
....*....|....*.
gi 569008203 122 ALAGIALTLLSFTQQH 137
Cdd:pfam04103 73 AVAGIILLSLSLALLT 88
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
413-712 |
1.39e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 79.21 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 413 QETPPQETPSQGTPYQDLPyqvllikdTSPQGTPYQYILTKEIPFQETPSQGTLSQESPSqwtlSKGTPSQGTSPKGTPS 492
Cdd:PHA03247 2704 PPPTPEPAPHALVSATPLP--------PGPAAARQASPALPAAPAPPAVPAGPATPGGPA----RPARPPTTAGPPAPAP 2771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 493 QVTPPQGTPSQGTPSEGTSLQVS---------PSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPqgTPSEMTPPQ 563
Cdd:PHA03247 2772 PAAPAAGPPRRLTRPAVASLSESreslpspwdPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP--PPPGPPPPS 2849
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 564 GTPSEGTSPQGTPSEETPPQGTPSEGTLPQgtpsqgTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSE 643
Cdd:PHA03247 2850 LPLGGSVAPGGDVRRRPPSRSPAAKPAAPA------RPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQP 2923
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 569008203 644 GTPPQGTPSEGTP--SQETVPQETPPQKLSFQDILTKDRSSQETAYQETPF-QDLVTQNRPSQDSQYKETPS 712
Cdd:PHA03247 2924 PPPPQPQPPPPPPprPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVpRFRVPQPAPSREAPASSTPP 2995
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
477-686 |
1.29e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 72.33 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 477 SKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVT-PSQGTPSEGTSLQVSPSEVTPPQGT 555
Cdd:PRK07764 605 SSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAvPDASDGGDGWPAKAGGAAPAAPPPA 684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 556 PSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQEt 635
Cdd:PRK07764 685 PAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA- 763
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 569008203 636 lpretPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDIltkdRSSQETA 686
Cdd:PRK07764 764 -----PAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDR----RDAEEVA 805
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
461-727 |
2.72e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.43 E-value: 2.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 461 PSQGTLSQESPSqwTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTP----SEVTPSQGTP 536
Cdd:PHA03247 2786 PAVASLSESRES--LPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplgGSVAPGGDVR 2863
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 537 SEGTSLQVSPSEVTP--------PQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQG---- 604
Cdd:PHA03247 2864 RRPPSRSPAAKPAAParppvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPqppl 2943
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 605 TPSEGTPPQGTPSQGTP-------------------PQGTPSegtpsqetlpRETPSEGTPP-QGTPSEGTPSQET---V 661
Cdd:PHA03247 2944 APTTDPAGAGEPSGAVPqpwlgalvpgrvavprfrvPQPAPS----------REAPASSTPPlTGHSLSRVSSWASslaL 3013
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 569008203 662 PQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQDSqykETPSQEIFFQDTPFQNTPS 727
Cdd:PHA03247 3014 HEETDPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDP---LPPEPHDPFAHEPDPATPE 3076
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
415-637 |
1.05e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.50 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 415 TPPQETPSQGTPYQDLPyqvlliKDTSPQGTPYQyILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQV 494
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPR------RLTRPAVASLS-ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT 2837
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 495 TPPQgTPSQGTPSEGTSLQVSP----SEVTPPQGTPSEVTP---------SQGTPSEGTSLQVSPSEVTPPQGTPSEMTP 561
Cdd:PHA03247 2838 APPP-PPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAparppvrrlARPAVSRSTESFALPPDQPERPPQPQAPPP 2916
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 562 PQGTPSEGTSPQGTPSEETPPQG----TPSEGTLPQGTPSQGTPPQG----TPSEGTPPQGTPSQGTPPQGTPSEGTPSQ 633
Cdd:PHA03247 2917 PQPQPQPPPPPQPQPPPPPPPRPqpplAPTTDPAGAGEPSGAVPQPWlgalVPGRVAVPRFRVPQPAPSREAPASSTPPL 2996
|
....
gi 569008203 634 ETLP 637
Cdd:PHA03247 2997 TGHS 3000
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
416-728 |
1.09e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.50 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 416 PPQETPSQGTPYQDLPYqvllikDTSPQGTPYQYILTKEIPFQETPSQG-TLSQESPSQWTLSKGTPSQGTSP--KGTPS 492
Cdd:PHA03247 2613 PPSPLPPDTHAPDPPPP------SPSPAANEPDPHPPPTVPPPERPRDDpAPGRVSRPRRARRLGRAAQASSPpqRPRRR 2686
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 493 QVTPPQGT-------PSQGTPSEGTSLQVSPSEVTPP----QGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTP 561
Cdd:PHA03247 2687 AARPTVGSltsladpPPPPPTPEPAPHALVSATPLPPgpaaARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGP 2766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 562 PQGTPSEGtSPQGTPSEETPPQGTPSEGTLPQG----TPSQGTPPQGTPSEGTPPQGTPSQGTPPqgtPSEGTPSQETLP 637
Cdd:PHA03247 2767 PAPAPPAA-PAAGPPRRLTRPAVASLSESRESLpspwDPADPPAAVLAPAAALPPAASPAGPLPP---PTSAQPTAPPPP 2842
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 638 RETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQD-----ILTKDRSSQETAYQETPFQDLVTQNRPSQDSQYKETPS 712
Cdd:PHA03247 2843 PGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPArppvrRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922
|
330
....*....|....*.
gi 569008203 713 QEIFFQDTPFQNTPSQ 728
Cdd:PHA03247 2923 PPPPPQPQPPPPPPPR 2938
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
467-660 |
1.26e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.78 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 467 SQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVS- 545
Cdd:PRK07764 601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAa 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 546 ----PSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTP 621
Cdd:PRK07764 681 pppaPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPP 760
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 569008203 622 PQGTPSEGTPSQETLP-RETPSEGTPPQGTPSEGTPSQET 660
Cdd:PRK07764 761 PPAPAPAAAPAAAPPPsPPSEEEEMAEDDAPSMDDEDRRD 800
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
491-728 |
3.30e-10 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 64.70 E-value: 3.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 491 PSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPsegtsLQVSPSEVTPPqGTPSEMTPPQGTPSEgT 570
Cdd:PHA03378 590 PSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRP-----LRMQPITFNVL-VFPTPHQPPQVEITP-Y 662
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 571 SPQGTPSEETPPQGTPSegtlpqgTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGT 650
Cdd:PHA03378 663 KPTWTQIGHIPYQPSPT-------GANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRAR 735
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569008203 651 PSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQDSQYKETPSQEIFFQDTPFQNTPSQ 728
Cdd:PHA03378 736 PPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRA 813
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
484-667 |
4.63e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 64.24 E-value: 4.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 484 GTSPKGtpSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTP-PQGTPSEMTPP 562
Cdd:PRK07764 589 GPAPGA--AGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPkHVAVPDASDGG 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 563 QGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEG-----TPPQGTPSQGTPPQGTPSEGTPSQETlP 637
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQaddpaAQPPQAAQGASAPSPAADDPVPLPPE-P 745
|
170 180 190
....*....|....*....|....*....|
gi 569008203 638 RETPSEGTPPQGTPSEGTPSQETVPQETPP 667
Cdd:PRK07764 746 DDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
497-668 |
2.65e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 61.54 E-value: 2.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 497 PQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTP-PQGTPSEGTSPQGT 575
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPkHVAVPDASDGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 576 PSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGT 655
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP 749
|
170
....*....|...
gi 569008203 656 PSQETVPQETPPQ 668
Cdd:PRK07764 750 DPAGAPAQPPPPP 762
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
452-667 |
5.57e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 60.96 E-value: 5.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 452 TKEIPFQETPSQGTLSQE----SPSQWTLS---------KGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSE 518
Cdd:PHA03307 64 RFEPPTGPPPGPGTEAPAnesrSTPTWSLStlapasparEGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGS 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 519 VTPPQGTPSEVTPSQGTPSEGTslQVSPSEVTPPQGTPSEMTPPQGTPSE-------GTSPQGTPSEETPPQGTPSEGTL 591
Cdd:PHA03307 144 PGPPPAASPPAAGASPAAVASD--AASSRQAALPLSSPEETARAPSSPPAepppstpPAAASPRPPRRSSPISASASSPA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 592 PQGTPSQGTPPQGTPSEGTPPQGtPSQGTPPQGTPSEGTPSQETLPR-----ETPSEGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PHA03307 222 PAPGRSAADDAGASSSDSSSSES-SGCGWGPENECPLPRPAPITLPTriweaSGWNGPSSRPGPASSSSSPRERSPSPSP 300
|
.
gi 569008203 667 P 667
Cdd:PHA03307 301 S 301
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
478-667 |
8.12e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.34 E-value: 8.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 478 KGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVT-PPQG-T 555
Cdd:PHA03247 2605 RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASsPPQRpR 2684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 556 PSEMTPPQGTPSEGTSPQGTPSE-ETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQ-----GTPSQGTPPQGTPSEG 629
Cdd:PHA03247 2685 RRAARPTVGSLTSLADPPPPPPTpEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAvpagpATPGGPARPARPPTTA 2764
|
170 180 190
....*....|....*....|....*....|....*...
gi 569008203 630 TPSQETLPReTPSEGTPPQGTPSEGTPSQETVPQETPP 667
Cdd:PHA03247 2765 GPPAPAPPA-APAAGPPRRLTRPAVASLSESRESLPSP 2801
|
|
| Not5 |
COG5665 |
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]; |
460-767 |
1.18e-08 |
|
CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription];
Pssm-ID: 444384 [Multi-domain] Cd Length: 874 Bit Score: 59.68 E-value: 1.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 460 TPSQGTLSQESPSQwtlskGTPSQGTSPkgtPSQVTPPQGTPS----QGTPSEGTSLQVsPSEVTPPQGTPSEvtPSQGT 535
Cdd:COG5665 245 TPPATPATEEKSSQ-----QPKSQPTSP---SGGTTPPSTNQLttsnTPTSTAKAQPQP-PTKKQPAKEPPSD--TASGN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGTSLQVSPSEVTPPQGTPSEMTPPQ-----------GTPSEGTSPQ---GTPSEETPPQ------GTPSEGTLPQ-- 593
Cdd:COG5665 314 PSAPSVLINSDSPTSEDPATASVPTTEEttafttpssvpSTPAEKDTPAtdlATPVSPTPPEtsvdkkVSPDSATSSTks 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 594 ----GTPSQGTPPQGTPSEGTPPQGT-PSQGTPPQGTPSEGTPSQETLPRET-PSEGTPPQGTPSEGTPSQETVPQETPP 667
Cdd:COG5665 394 ekegGTASSPMPPNIAIGAKDDVDATdPSQEAKEYTKNAPMTPEADSAPESSvRTEASPSAGSDLEPENTTLRDPAPNAI 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 668 QKLSFQDILTKDRSSQETAYQETPFQdlvtqnrPSQDSQYKETPSQEIFFQDTPFQNTPSQNIQYQDILSQDKISQGSQT 747
Cdd:COG5665 474 PPPEDPSTIGRLSSGDKLANETGPPV-------IRRDSTPSSTADQSIVGVLAFGLDQRTQAEISVEAASRSNPLLNSQV 546
|
330 340
....*....|....*....|
gi 569008203 748 QNSVSQemASSDLQVLNTQV 767
Cdd:COG5665 547 KSFPLG--KRSEGAKGKTQT 564
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
479-671 |
4.60e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 4.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 479 GTPSQGTSPKgTPsqVTPPQGTPSQGTPSEgtslqvSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSE 558
Cdd:PHA03247 2590 DAPPQSARPR-AP--VDDRGDPRGPAPPSP------LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR 2660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 559 MTPP-----QGTPSEGTSPqgtPSEETPPQGTPSEGTL-------PQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTP 626
Cdd:PHA03247 2661 VSRPrrarrLGRAAQASSP---PQRPRRRAARPTVGSLtsladppPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 569008203 627 SEGTPSQETLPRETPSEGTP--PQGTPSEGTPSQETVPQETPPQKLS 671
Cdd:PHA03247 2738 APAPPAVPAGPATPGGPARParPPTTAGPPAPAPPAAPAAGPPRRLT 2784
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
368-671 |
5.74e-08 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 57.47 E-value: 5.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 368 QDNQSQdTPSQYTPSQDIQFQDMLAQdisfQEIQSQESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPy 447
Cdd:pfam03154 139 QDNRST-SPSIPSPQDNESDSDSSAQ----QQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSP- 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 448 qyiLTKEIPFQETPSQG--TLSQESPS---QWTLSKGTPSQGTSPKGTPSQVtPPQGTPSQG----TPSEGTSLQVSPSE 518
Cdd:pfam03154 213 ---ATSQPPNQTQSTAAphTLIQQTPTlhpQRLPSPHPPLQPMTQPPPPSQV-SPQPLPQPSlhgqMPPMPHSLQTGPSH 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 519 V---TPPQ--GTPSEVTPSQGTPSEGTSL--------QVSPSEVTPPQGTPSE-------------MTPPQGTP------ 566
Cdd:pfam03154 289 MqhpVPPQpfPLTPQSSQSQVPPGPSPAApgqsqqriHTPPSQSQLQSQQPPReqplppaplsmphIKPPPTTPipqlpn 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 567 ---------SEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPP---------QGTPSEGTPPQGTPSQGTPPQGT--- 625
Cdd:pfam03154 369 pqshkhpphLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPplqlmpqsqQLPPPPAQPPVLTQSQSLPPPAAshp 448
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 569008203 626 ---PSEGTPSQETLPRETPSEGTPPQGTPSEGTP--SQETVPQETPPQKLS 671
Cdd:pfam03154 449 ptsGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPtsTSSAMPGIQPPSSAS 499
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
382-672 |
5.96e-08 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 57.37 E-value: 5.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 382 SQDIQFQDMLAQDISFQEIQSQESPNQDVLYQETPPQETPSQGTPYQ------DLPYQV--LLIKDTSP----QGTPYQY 449
Cdd:PHA03377 336 EDVIQTAFRKAQRQGLSMLATGGEPRGDATSETSSDEDTGRQGSDVElessddELPYIDpnMEPVQQRPvmfvSRVPWRK 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 450 ILTKEIPFQET-PSQGTLSQESPSQwtlSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSE 528
Cdd:PHA03377 416 PRTLPWPTPKThPVKRTLVKTSGRS---DEAEQAQSTPERPGPSDQPSVPVEPAHLTPVEHTTVILHQPPQSPPTVAIKP 492
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 529 VTPSQGTPS------EGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEE-TPPQGTPSEGTLPQGTPSQGTP 601
Cdd:PHA03377 493 APPPSRRRRgacvvyDDDIIEVIDVETTEEEESVTQPAKPHRKVQDGFQRSGRRQKRaTPPKVSPSDRGPPKASPPVMAP 572
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569008203 602 PQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPS-------QETVPQETPPQKLSF 672
Cdd:PHA03377 573 PSTGPRVMATPSTGPRDMAPPSTGPRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSvvrmflrERLLEQSTGPKPKSF 650
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
413-667 |
1.11e-07 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 55.84 E-value: 1.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 413 QETPPQETPSQGTPyQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGT-P 491
Cdd:COG5180 211 QEEPPDLTGGADHP-RPEAASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSeP 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 492 SQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEgtSLQVSPSEVTPPQGTPSEMTPPQ----GTPS 567
Cdd:COG5180 290 QSDAPEAETARPIDVKGVASAPPATRPVRPPGGARDPGTPRPGQPTE--RPAGVPEAASDAGQPPSAYPPAEeavpGKPL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 568 EGTSPQGTPSEETPPQGTPSEGT---LPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGT--PSQETLPRETPS 642
Cdd:COG5180 368 EQGAPRPGSSGGDGAPFQPPNGApqpGLGRRGAPGPPMGAGDLVQAALDGGGRETASLGGAAGGAGqgPKADFVPGDAES 447
|
250 260
....*....|....*....|....*
gi 569008203 643 EGTPPQgtpSEGTPSQETVPQETPP 667
Cdd:COG5180 448 VSGPAG---LADQAGAAASTAMADF 469
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
446-702 |
2.63e-07 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 55.31 E-value: 2.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 446 PYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQ-- 523
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpa 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 524 GT---PSEVTPS-----QGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPS-EGTSPQGTPSEETPPQGTPS-EGTLPQ 593
Cdd:pfam05109 480 GTtsgASPVTPSpsprdNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTpNATSPTLGKTSPTSAVTTPTpNATSPT 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 594 GTPSQGTPPQGTPSEG-TPPQGTPSQGTPPQGTPS--EGTPSQETL------PRETPSEGTPPQGTPSEGTPSQETVPQE 664
Cdd:pfam05109 560 PAVTTPTPNATIPTLGkTSPTSAVTTPTPNATSPTvgETSPQANTTnhtlggTSSTPVVTSPPKNATSAVTTGQHNITSS 639
|
250 260 270
....*....|....*....|....*....|....*...
gi 569008203 665 TpPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPS 702
Cdd:pfam05109 640 S-TSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPT 676
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
412-667 |
4.01e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.94 E-value: 4.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 412 YQETPPQETPSQGTPYQDLPYQVLLIKDTSPQ-GTPYQYILTKEIPFQETPsqgtlsqesPSQWTLSKGTPSQGTSPKGT 490
Cdd:PHA03247 2480 YRRPAEARFPFAAGAAPDPGGGGPPDPDAPPApSRLAPAILPDEPVGEPVH---------PRMLTWIRGLEELASDDAGD 2550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 491 PSQVTPPQGTPSQGTPSEGTSlQVSPSEVTP--------PQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPP 562
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPP-RPAPRPSEPavtsrarrPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPP 2629
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 563 QGTPSEGTSPQGTPSEETPPQG-----TPSEGTLPQGTPSQGTPPQGTpsegTPPQG-TPSQGTPPQG--TPSEGTPSQE 634
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERprddpAPGRVSRPRRARRLGRAAQAS----SPPQRpRRRAARPTVGslTSLADPPPPP 2705
|
250 260 270
....*....|....*....|....*....|....*..
gi 569008203 635 TLPRETPSEGTP----PQGTPSEGTPSQETVPQETPP 667
Cdd:PHA03247 2706 PTPEPAPHALVSatplPPGPAAARQASPALPAAPAPP 2742
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
460-669 |
4.88e-07 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 53.81 E-value: 4.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 460 TPSQGTLSQESPSQWTLSKGTPSQGTSpkGTPSQVTPPQGTPSQ----GTPSEGTSLQVSPSeVTPPQGTPSEVTPSQGT 535
Cdd:pfam17823 174 APRTAASSTTAASSTTAASSAPTTAAS--SAPATLTPARGISTAatatGHPAAGTALAAVGN-SSPAAGTVTAAVGTVTP 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGT----SLQVSPSEVTPPQGTP--SEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEG 609
Cdd:pfam17823 251 AALATlaaaAGTVASAAGTINMGDPhaRRLSPAKHMPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNT 330
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 610 TPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQK 669
Cdd:pfam17823 331 TLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEVEATSPTTQPSPLLPTQ 390
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
461-712 |
7.53e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 53.54 E-value: 7.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 461 PSQGTlsqESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGT----P 536
Cdd:PTZ00449 536 DSKES---DEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTrpksP 612
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 537 SEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETP-PQGTPS------------EGTLPQGTPSQGTPPQ 603
Cdd:PTZ00449 613 KLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPkPPKSPKppfdpkfkekfyDDYLDAAAKSKETKTT 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 604 GTPSEG-------TPPQGTPSQGTPPQGTPSEgTPSQETLPRETPSEGTPPQGTPSE--GTPSQETV-----PQETPPQK 669
Cdd:PTZ00449 693 VVLDESfesilkeTLPETPGTPFTTPRPLPPK-LPRDEEFPFEPIGDPDAEQPDDIEffTPPEEERTffhetPADTPLPD 771
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 569008203 670 LSFQDILTKDRSSqETAYQETPFQdlvtqnRPSQDSQYKETPS 712
Cdd:PTZ00449 772 ILAEEFKEEDIHA-ETGEPDEAMK------RPDSPSEHEDKPP 807
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
471-669 |
7.91e-07 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 53.22 E-value: 7.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 471 PSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSE---GTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSL---QV 544
Cdd:COG3469 11 TAGGASATAVTLLGAAATAASVTLTAATATTVVSTTGSvvvAASGSAGSGTGTTAASSTAATSSTTSTTATATAAaaaAT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 545 SPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPP-QGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQ 623
Cdd:COG3469 91 STSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSStAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTT 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 569008203 624 GTPSEGTPSQETlPRETPSEGTPPQGTPSEGTPSQETVPQETPPQK 669
Cdd:COG3469 171 TTTSASTTPSAT-TTATATTASGATTPSATTTATTTGPPTPGLPKH 215
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
513-636 |
8.98e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 53.45 E-value: 8.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 513 QVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGtPSEETPPQGTPSEGTLP 592
Cdd:PRK07764 392 GAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGA-PSPPPAAAPSAQPAPAP 470
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 569008203 593 QGTPSQGTPPQGTPSEGTPPQGTPSQgtPPQGTPSEGTPSQETL 636
Cdd:PRK07764 471 AAAPEPTAAPAPAPPAAPAPAAAPAA--PAAPAAPAGADDAATL 512
|
|
| Chi1 |
COG3469 |
Chitinase [Carbohydrate transport and metabolism]; |
460-653 |
1.07e-06 |
|
Chitinase [Carbohydrate transport and metabolism];
Pssm-ID: 442692 [Multi-domain] Cd Length: 534 Bit Score: 52.83 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 460 TPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSeg 539
Cdd:COG3469 33 TLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTS-- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 540 tslqVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSegtlPQGTPSQGTPPQGTPSEGTPPQGTPSQG 619
Cdd:COG3469 111 ----TVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVS----GTETATGGTTTTSTTTTTTSASTTPSAT 182
|
170 180 190
....*....|....*....|....*....|....
gi 569008203 620 TPPQGTPSEGTPSQETLPreTPSEGTPPQGTPSE 653
Cdd:COG3469 183 TTATATTASGATTPSATT--TATTTGPPTPGLPK 214
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
484-657 |
1.14e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 52.93 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 484 GTSPKGTPSQVTPPQGTPSQG-TPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQG---TPSEM 559
Cdd:PRK07003 364 GGGAPGGGVPARVAGAVPAPGaRAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATadrGDDAA 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQgTPSEGTPPQGTPSQGTPPQGTPSEG-----TPSQE 634
Cdd:PRK07003 444 DGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPD-AAFEPAPRAAAPSAATPAAVPDARApaaasREDAP 522
|
170 180
....*....|....*....|...
gi 569008203 635 TLPRETPSEGTPPqgTPSEGTPS 657
Cdd:PRK07003 523 AAAAPPAPEARPP--TPAAAAPA 543
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
561-674 |
1.30e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 52.47 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 561 PPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEgTPPQGTPSQGTPPQGTPSEGTPSQETLPRET 640
Cdd:PRK14971 389 APQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVP-VNPPSTAPQAVRPAQFKEEKKIPVSKVSSLG 467
|
90 100 110
....*....|....*....|....*....|....
gi 569008203 641 PSEGTPPQGTPSEGTPSQETVPqeTPPQKLSFQD 674
Cdd:PRK14971 468 PSTLRPIQEKAEQATGNIKEAP--TGTQKEIFTE 499
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
470-649 |
1.32e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.87 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 470 SPSQWTLSKGTPSQGTSPKGTPSQVTPPQ----GTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVS 545
Cdd:PHA03307 271 EASGWNGPSSRPGPASSSSSPRERSPSPSpsspGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRS 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 546 PS--EVTPPQGTPSEMTPPQGTPSEGTSPQgTPSEETPPQGTPSEGtlPQGTPSQGTPPqgTPSEGTPPQGTPSQGTPPQ 623
Cdd:PHA03307 351 PSpsRPPPPADPSSPRKRPRPSRAPSSPAA-SAGRPTRRRARAAVA--GRARRRDATGR--FPAGRPRPSPLDAGAASGA 425
|
170 180
....*....|....*....|....*...
gi 569008203 624 GTPSE--GTPSQETLPRETPsegtPPQG 649
Cdd:PHA03307 426 FYARYplLTPSGEPWPGSPP----PPPG 449
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
440-712 |
1.66e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 52.27 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 440 TSPQGTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSP-KGTPSQVTPPQGTPSQGTPSEGTSlqvspse 518
Cdd:pfam17823 71 TLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAaSSSPSSAAQSLPAAIAALPSEAFS------- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 519 vTPPQGTPSevTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQ----G 594
Cdd:pfam17823 144 -APRAAACR--ANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAatatG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 595 TPSQGTPPQGTPSEGTPPQ-GTPSQGTPPQGTPSEGTPSQETLpreTPSEGTPPQGTPSEGTPSQEtvpQETPPQKLSFQ 673
Cdd:pfam17823 221 HPAAGTALAAVGNSSPAAGtVTAAVGTVTPAALATLAAAAGTV---ASAAGTINMGDPHARRLSPA---KHMPSDTMARN 294
|
250 260 270
....*....|....*....|....*....|....*....
gi 569008203 674 DILTKDRSSQETAYQetpfqdlVTQNRPSQDSQYKETPS 712
Cdd:pfam17823 295 PAAPMGAQAQGPIIQ-------VSTDQPVHNTAGEPTPS 326
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
481-685 |
1.66e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.48 E-value: 1.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQGTPSQgtPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPsevTPPQGTPSEMT 560
Cdd:PHA03307 136 EMLRPVGSPGPPPAASPPAAGAS--PAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPP---AAASPRPPRRS 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 561 PPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRET 640
Cdd:PHA03307 211 SPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSS 290
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 569008203 641 PSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQET 685
Cdd:PHA03307 291 PRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
484-626 |
2.80e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 51.91 E-value: 2.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 484 GTSPKGTPSQVTPPQGTPSQGTPsegtslqvspsevTPPQGTPsEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQ 563
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAA-------------APAPAAA-APAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAG 451
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 569008203 564 GTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPseGTPPQGTPSQGTPPQGTP 626
Cdd:PRK07764 452 GAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP--AAPAAPAAPAGADDAATL 512
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
473-584 |
3.84e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 51.31 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 473 QWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPP 552
Cdd:PRK14971 361 QLTQKGDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPP 440
|
90 100 110
....*....|....*....|....*....|..
gi 569008203 553 QGTPSEMTPPQGTPSEGTSPQGTPSEETPPQG 584
Cdd:PRK14971 441 STAPQAVRPAQFKEEKKIPVSKVSSLGPSTLR 472
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
398-657 |
4.46e-06 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 50.83 E-value: 4.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 398 QEIQSQESPNQDVLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQgtpyqyiltKEIPFQETPSQGTLSQESPSQWTLS 477
Cdd:COG5180 245 RPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQ---------SDAPEAETARPIDVKGVASAPPATR 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 478 KGTPSQGTSPKGTPSQVTPPQgTPsQGTPSEGTSLQVSPSEVtPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPS 557
Cdd:COG5180 316 PVRPPGGARDPGTPRPGQPTE-RP-AGVPEAASDAGQPPSAY-PPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNGAPQ 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 558 EMTPPQGTPseGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTppQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLP 637
Cdd:COG5180 393 PGLGRRGAP--GPPMGAGDLVQAALDGGGRETASLGGAAGGAG--QGPKADFVPGDAESVSGPAGLADQAGAAASTAMAD 468
|
250 260
....*....|....*....|
gi 569008203 638 RETPSEGTPPQGTPSEGTPS 657
Cdd:COG5180 469 FVAPVTDATPVDVADVLGVR 488
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
456-628 |
6.61e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.37 E-value: 6.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 456 PFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGT 535
Cdd:PRK07764 635 APAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQA 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSegtlPQGTPSQGTPPQGTPSEGTPPQGT 615
Cdd:PRK07764 715 DDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAP----AAAPAAAPPPSPPSEEEEMAEDDA 790
|
170
....*....|...
gi 569008203 616 PSQGTPPQGTPSE 628
Cdd:PRK07764 791 PSMDDEDRRDAEE 803
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
480-667 |
6.70e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 50.48 E-value: 6.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 480 TPSQGTSPKGTPSQVTPPQGTPSQGTPS-EGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQV----SPSEVTPPQG 554
Cdd:PRK08691 359 APLAAASCDANAVIENTELQSPSAQTAEkETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPvsnqENNDVPPWED 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 555 TPSEMTPPQGT-PSEGTSPQGTPSEETPPqgtpsegtlpqgtPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQ 633
Cdd:PRK08691 439 APDEAQTAAGTaQTSAKSIQTASEAETPP-------------ENQVSKNKAADNETDAPLSEVPSENPIQATPNDEAVET 505
|
170 180 190
....*....|....*....|....*....|....
gi 569008203 634 ETLPRETPSEGTPPQGTPSEGTPSQETVpqETPP 667
Cdd:PRK08691 506 ETFAHEAPAEPFYGYGFPDNDCPPEDGA--EIPP 537
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
497-666 |
6.94e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.55 E-value: 6.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 497 PQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTP 576
Cdd:PHA03307 63 DRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVG 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 577 SEETPPQGTPSEGTLPqgtPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSegtpsqETLPRETPSEGTPPqGTPSEGTP 656
Cdd:PHA03307 143 SPGPPPAASPPAAGAS---PAAVASDAASSRQAALPLSSPEETARAPSSPP------AEPPPSTPPAAASP-RPPRRSSP 212
|
170
....*....|
gi 569008203 657 SQETVPQETP 666
Cdd:PHA03307 213 ISASASSPAP 222
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
524-649 |
7.45e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.37 E-value: 7.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 524 GTPSEVTPSQGTPSEGTslQVSPSEVTPPQGTPSEMTPPQGTPSEgTSPQGTPSEETPPQGTPSEGTLPQGtPSQGTPPQ 603
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAA--AAAPAAAPAPAAAAPAAAAAPAPAAA-PQPAPAPAPAPAPPSPAGNAPAGGA-PSPPPAAA 461
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 569008203 604 GTPSEGTPPQGTPSQGTPPQGTPSEGTPSQEtlPRETPSEGTPPQG 649
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA--APAAPAAPAAPAG 505
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
549-663 |
7.70e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.37 E-value: 7.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 549 VTPPQGTPSEMTPPQGTPsegTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSE-GTPPQGTPSQGTPPQGTPS 627
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAA---APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNaPAGGAPSPPPAAAPSAQPA 467
|
90 100 110
....*....|....*....|....*....|....*..
gi 569008203 628 -EGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQ 663
Cdd:PRK07764 468 pAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPA 504
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
500-668 |
8.01e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.55 E-value: 8.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 500 TPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSlqvsPSEVTPPQGTPSEmtPPQGTPSEGTSPQGTPSEE 579
Cdd:PHA03307 24 PPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRF----EPPTGPPPGPGTE--APANESRSTPTWSLSTLAP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 580 TPPQGTPSEGtlPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSegtPSQE 659
Cdd:PHA03307 98 ASPAREGSPT--PPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAS---SRQA 172
|
....*....
gi 569008203 660 TVPQETPPQ 668
Cdd:PHA03307 173 ALPLSSPEE 181
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
479-667 |
8.15e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.55 E-value: 8.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 479 GTPSQGTSPKGTPSQVTPPQGTPSQGTPSEG---TSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTslQVSPSEVTPPQGT 555
Cdd:PHA03307 18 GEFFPRPPATPGDAADDLLSGSQGQLVSDSAelaAVTVVAGAAACDRFEPPTGPPPGPGTEAPAN--ESRSTPTWSLSTL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 556 PSEMTPPQGTPSEGTSpqgtPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGT--PPQGTPSEGTPSQ 633
Cdd:PHA03307 96 APASPAREGSPTPPGP----SSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGasPAAVASDAASSRQ 171
|
170 180 190
....*....|....*....|....*....|....
gi 569008203 634 ETLPRETPSEGTPPQGTPSegtpsqETVPQETPP 667
Cdd:PHA03307 172 AALPLSSPEETARAPSSPP------AEPPPSTPP 199
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
416-768 |
9.86e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 50.08 E-value: 9.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 416 PPQETPSQGTPYQDLPYQvllikdtspqgTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVT 495
Cdd:PRK10263 381 PQQSQYAQPAVQYNEPLQ-----------QPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 496 PPQGTPSQGTPS-EGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEvtPPQGTPSEMTPPQGTPSEGTSPQG 574
Cdd:PRK10263 450 EEQQSTFAPQSTyQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPAR--PPLYYFEEVEEKRAREREQLAAWY 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 575 TPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTpsqgtpPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEG 654
Cdd:PRK10263 528 QPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGV------KKATLATGAAATVAAPVFSLANSGGPRPQVKEG 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 655 TPSQETVPQE----TPPQKLSFQDILTKDRSSQETAYQEtpfqdlvTQNRPSQDSQYKETPSQEIFFQDTPFQNTPSQNI 730
Cdd:PRK10263 602 IGPQLPRPKRirvpTRRELASYGIKLPSQRAAEEKAREA-------QRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQ 674
|
330 340 350
....*....|....*....|....*....|....*...
gi 569008203 731 QYQDILSQDKISQGSQTQNSVSQEMASsdlQVLNTQVQ 768
Cdd:PRK10263 675 RYGEQYQHDVPVNAEDADAAAEAELAR---QFAQTQQQ 709
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
417-669 |
1.19e-05 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 49.29 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 417 PQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQETPSQGtlsQESPSQWTLSKGTPSQGTSPKG------- 489
Cdd:COG5180 163 AKDPDGDSASTLPPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVKDEA---QEEPPDLTGGADHPRPEAASSPkvdppst 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 490 --TPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEvtPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPS 567
Cdd:COG5180 240 seARSRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGL--PVLEAGSEPQSDAPEAETARPIDVKGVASAPPATRPV 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 568 EGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPP 647
Cdd:COG5180 318 RPPGGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNGAPQPGLGR 397
|
250 260
....*....|....*....|..
gi 569008203 648 QGTPseGTPSQETVPQETPPQK 669
Cdd:COG5180 398 RGAP--GPPMGAGDLVQAALDG 417
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
481-714 |
1.54e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 49.38 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQgTPSQGTPSEGTSLQVSPSEVTPPQGTPSE---VTPSQGTPSEGTSLQVSPSEVTPPQGTPS 557
Cdd:pfam03154 94 PERATAKKSKTQEISRPN-SPSEGEGESSDGRSVNDEGSSDPKDIDQDnrsTSPSIPSPQDNESDSDSSAQQQILQTQPP 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 558 EMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTL-PQGTPSQGTPPQGTPSEGTP-----------PQGTPSQGTPPQGT 625
Cdd:pfam03154 173 VLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVpPQGSPATSQPPNQTQSTAAPhtliqqtptlhPQRLPSPHPPLQPM 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 626 PSEGTPSQ---ETLPRETPSEGTPPQGTPSEGTPSQetVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPS 702
Cdd:pfam03154 253 TQPPPPSQvspQPLPQPSLHGQMPPMPHSLQTGPSH--MQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPS 330
|
250
....*....|..
gi 569008203 703 QDSQYKETPSQE 714
Cdd:pfam03154 331 QSQLQSQQPPRE 342
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
483-743 |
2.24e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 48.92 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 483 QGTSPKGTPSQVTPPQGtPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPP 562
Cdd:PTZ00449 507 HDEPPEGPEASGLPPKA-PGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDP 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 563 QgTPSEGTSPQGTPSEETPPQGT-PSEGTLPQGT--PSQGTPPQGTPSEGTPPQGT-PSQGTPPQGTPSEGTPSQETLPR 638
Cdd:PTZ00449 586 K-HPKDPEEPKKPKRPRSAQRPTrPKSPKLPELLdiPKSPKRPESPKSPKRPPPPQrPSSPERPEGPKIIKSPKPPKSPK 664
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 639 ---------------ETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQ 703
Cdd:PTZ00449 665 ppfdpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQP 744
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 569008203 704 DSQYKETP--SQEIFFQDTPfQNTPSQNIQYQDILSQDKISQ 743
Cdd:PTZ00449 745 DDIEFFTPpeEERTFFHETP-ADTPLPDILAEEFKEEDIHAE 785
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
560-668 |
2.79e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 48.52 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TPPQGTPSEGTSPQGTPSEETP----PQGTPSEGTLPQGTPSQGTP-PQGTPSEGTP----PQGTPSQGTPPQGTPSegt 630
Cdd:PRK14959 379 SAPSGSAAEGPASGGAATIPTPgtqgPQGTAPAAGMTPSSAAPATPaPSAAPSPRVPwddaPPAPPRSGIPPRPAPR--- 455
|
90 100 110
....*....|....*....|....*....|....*...
gi 569008203 631 psqetLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQ 668
Cdd:PRK14959 456 -----MPEASPVPGAPDSVASASDAPPTLGDPSDTAEH 488
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
468-632 |
2.96e-05 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 47.74 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 468 QESPSQWTLSKGTP-SQGTSPKGTPSQVTPPQGTPSQG-TPSEGTSLQVSpsevTPPQGTPSEVTPSQGTPSegtslQVS 545
Cdd:pfam05539 166 KEPKTAVTTSKTTSwPTEVSHPTYPSQVTPQSQPATQGhQTATANQRLSS----TEPVGTQGTTTSSNPEPQ-----TEP 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 546 PSEVTPPQGTPSEM--TPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTpseGTPpqgTPSQGTPPQ 623
Cdd:pfam05539 237 PPSQRGPSGSPQHPpsTTSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTTKRQET---GRP---TPRPTATTQ 310
|
....*....
gi 569008203 624 GTPSEGTPS 632
Cdd:pfam05539 311 SGSSPPHSS 319
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
481-684 |
3.82e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 3.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVtPPQGTPSEVTPSQGTPSEGTSLQVSpsEVTPPQGTPSEMT 560
Cdd:PHA03247 271 TARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLAL-PAPPDPPPPAPAGDAEEEDDEDGAM--EVVSPLPRPRQHY 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 561 P--------PQGTPSegTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTP-PQGTPSEGTPPQGTPSQGTPPQGTPSEGTP 631
Cdd:PHA03247 348 PlgfpkrrrPTWTPP--SSLEDLSAGRHHPKRASLPTRKRRSARHAATPfARGPGGDDQTRPAAPVPASVPTPAPTPVPA 425
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 569008203 632 SQETLPRETPSEGTPPQG----TPSEGTPSQETVPQETPPQKLSFQDILT--KDRSSQE 684
Cdd:PHA03247 426 SAPPPPATPLPSAEPGSDdgpaPPPERQPPAPATEPAPDDPDDATRKALDalRERRPPE 484
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
475-663 |
4.08e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 47.99 E-value: 4.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 475 TLSKGTPSQG-TSPkgTPSQVTPPQGTPSQGTPSEGTSL---QVSPSEVTPPQGTPSEVTPSQG--TPSEGTSLQVSPSE 548
Cdd:pfam05109 573 TLGKTSPTSAvTTP--TPNATSPTVGETSPQANTTNHTLggtSSTPVVTSPPKNATSAVTTGQHniTSSSTSSMSLRPSS 650
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 549 VT----PPQGTPSEMTPP--------------QGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGT 610
Cdd:pfam05109 651 ISetlsPSTSDNSTSHMPlltsahptggenitQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGT 730
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 611 PPQGTPSQGTP-------PQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQ 663
Cdd:pfam05109 731 PPKNATSPQAPsgqktavPTVTSTGGKANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPR 790
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
486-666 |
4.45e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.01 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 486 SPKGTPSQVTPPQGTPSQGTPSEGTSLQVSpsEVTPPQGTPSEVTPSqGTPSEGTSLQVSPSEV---TPPQGTPSEMTPP 562
Cdd:PHA03247 305 APLALPAPPDPPPPAPAGDAEEEDDEDGAM--EVVSPLPRPRQHYPL-GFPKRRRPTWTPPSSLedlSAGRHHPKRASLP 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 563 QGT---PSEGTSP--QGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSqetlP 637
Cdd:PHA03247 382 TRKrrsARHAATPfaRGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPA----P 457
|
170 180
....*....|....*....|....*....
gi 569008203 638 RETPSEGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PHA03247 458 ATEPAPDDPDDATRKALDALRERRPPEPP 486
|
|
| SPT5 |
COG5164 |
Transcription elongation factor SPT5 [Transcription]; |
520-667 |
4.52e-05 |
|
Transcription elongation factor SPT5 [Transcription];
Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 47.33 E-value: 4.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 520 TPPQGTPSEVTPSQGTP--SEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSegTSPQGTPSEETPPQGTPSEGtlPQGTPS 597
Cdd:COG5164 4 YGPGKTGPSDPGGVTTPagSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGS--TTPAGNTGGTRPAGNQGATG--PAQNQG 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 598 QGTPPQgTPSEGTPPQGTPsqGTPPQGTPSEGTPSQETlPRETPSEGTPPQGTPSEGTPSQETVPQETPP 667
Cdd:COG5164 80 GTTPAQ-NQGGTRPAGNTG--GTTPAGDGGATGPPDDG-GATGPPDDGGSTTPPSGGSTTPPGDGGSTPP 145
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
461-689 |
4.76e-05 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 47.70 E-value: 4.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 461 PSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVtpPQGTPSQGTPSEGTSLQVSPSEVTP--PQGTPSEVTPSQGTPSE 538
Cdd:pfam09606 242 AMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGA--GQGGPGQPMGPPGQQPGAMPNVMSIgdQNNYQQQQTRQQQQQQG 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 539 GTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGT-------PSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTP 611
Cdd:pfam09606 320 GNHPAAHQQQMNQSVGQGGQVVALGGLNHLETWNPGNfgglganPMQRGQPGMMSSPSPVPGQQVRQVTPNQFMRQSPQP 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 612 ----PQGTPSQgtPPQGTPSEGTPSQETLPRETP-------SEGTPPQGTPSE--GTPSQETVPQETPPQklsfQDILTK 678
Cdd:pfam09606 400 svpsPQGPGSQ--PPQSHPGGMIPSPALIPSPSPqmsqqpaQQRTIGQDSPGGslNTPGQSAVNSPLNPQ----EEQLYR 473
|
250
....*....|.
gi 569008203 679 DRSSQETAYQE 689
Cdd:pfam09606 474 EKYRQLTKYIE 484
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
578-690 |
7.06e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 47.08 E-value: 7.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 578 EETPPQGTPSEGTLPQGT-PSQGTPPQ-GTPSEGTPPQG--TPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSE 653
Cdd:PRK14971 367 DDASGGRGPKQHIKPVFTqPAAAPQPSaAAAASPSPSQSsaAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQA 446
|
90 100 110
....*....|....*....|....*....|....*..
gi 569008203 654 GTPSQETVPQETPPQKLSFQDILTKdRSSQETAYQET 690
Cdd:PRK14971 447 VRPAQFKEEKKIPVSKVSSLGPSTL-RPIQEKAEQAT 482
|
|
| PHA03309 |
PHA03309 |
transcriptional regulator ICP4; Provisional |
473-671 |
8.75e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain] Cd Length: 2033 Bit Score: 47.16 E-value: 8.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 473 QWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQGTPsegtSLQVSPSevtPPQGTPSEVTPSqGTPSEGTSLQVSPSEVTPP 552
Cdd:PHA03309 1808 RWMISAGRSSSSSSSSSSSSSSSPSSRPSRSATP----SLSPSPS---PPRRAPVDRSRS-GRRRERDRPSANPFRWAPR 1879
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 553 QGTPSEMTPpqgtpsEGTSPQGTP--SEETPPQG----TPSEGTLpqgTPSQGTPPQGTPSEGTPPQGTPSQGTPpqgTP 626
Cdd:PHA03309 1880 QRSRADHSP------DGTAPGDAPlnLEDGPGRGrpiwTPSSATT---LPSRSGPEDSVDETETEDSAPPARLAP---SP 1947
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 569008203 627 SEGTPSQETLPRETPSEGTPPQGTPSEGTPSQET-VPQETPPQKLS 671
Cdd:PHA03309 1948 LETSRAEDSEDSEYPEYSNPRLGKSPPALKSREArRPSSKQPRRPS 1993
|
|
| Agg_substance |
NF033875 |
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ... |
560-709 |
9.94e-05 |
|
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.
Pssm-ID: 411439 [Multi-domain] Cd Length: 1306 Bit Score: 47.01 E-value: 9.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQ---GTPSQGTPPQGTPSEGTPSQETL 636
Cdd:NF033875 48 TQPGTTTVQPDNPDPQSGSETPKTAVSEEATVQKDTTSQPTKVEEVASEKNGAEqssATPNDTTNAQQPTVGAEKSAQEQ 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 637 PRETPSEGTPPQGTPSEGTPSQETVPQETP-PQKLSFQDIltkDRSSQETAYQ------ETPFQDLvtQNRPSQDSQYKE 709
Cdd:NF033875 128 PVVSPETTNEPLGQPTEVAPAENEANKSTSiPKEFETPDV---DKAVDEAKKDpnitvvEKPAEDL--GNVSSKDLAAKE 202
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
501-661 |
1.11e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 46.19 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 501 PSQGTPSEGTSlqvSPSEVTPPQgTPSEVTPSQGTPSEGtslqvspsEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEET 580
Cdd:pfam05539 169 KTAVTTSKTTS---WPTEVSHPT-YPSQVTPQSQPATQG--------HQTATANQRLSSTEPVGTQGTTTSSNPEPQTEP 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 581 PPQGTPSEGT--LPQGTPSQGTPPQGTPSEGTPPQGTPS-----QGTPPQGTPSEGTPSQETLpRETPSEGTPPQGTPSE 653
Cdd:pfam05539 237 PPSQRGPSGSpqHPPSTTSQDQSTTGDGQEHTQRRKTPPatsnrRSPHSTATPPPTTKRQETG-RPTPRPTATTQSGSSP 315
|
....*...
gi 569008203 654 GTPSQETV 661
Cdd:pfam05539 316 PHSSPPGV 323
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
480-666 |
1.56e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 45.97 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 480 TPSQGTSPKGTPSQ--VTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQV----SPSEVTPPQ 553
Cdd:PRK14086 89 DPSAGEPAPPPPHArrTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPgawpRAADDYGWQ 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 554 GTPSEMTPPQG-TPSEGTSPQGTPSEETPPQGTPSEGTlPQGTPSQGTPPQGTPS--EGTPPQGTPSQGTPPQGTPSEGT 630
Cdd:PRK14086 169 QQRLGFPPRAPyASPASYAPEQERDREPYDAGRPEYDQ-RRRDYDHPRPDWDRPRrdRTDRPEPPPGAGHVHRGGPGPPE 247
|
170 180 190
....*....|....*....|....*....|....*.
gi 569008203 631 PSQETLPRETPSEGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PRK14086 248 RDDAPVVPIRPSAPGPLAAQPAPAPGPGEPTARLNP 283
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
388-667 |
1.67e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.93 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 388 QDMLAQDISFQEIQSQESPNQDVlyqetPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQyilTKEIPFQETPSQGTLS 467
Cdd:PHA03307 171 QAALPLSSPEETARAPSSPPAEP-----PPSTPPAAASPRPPRRSSPISASASSPAPAPGR---SAADDAGASSSDSSSS 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 468 QESPSQWTlskgtpSQGTSPKGTPSQVTPPqGTPSQGTPSEGTSLQVSPSevtPPQGTPSEVTPSQGTPSEGTSLQVSPS 547
Cdd:PHA03307 243 ESSGCGWG------PENECPLPRPAPITLP-TRIWEASGWNGPSSRPGPA---SSSSSPRERSPSPSPSSPGSGPAPSSP 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 548 EVTPPQGTPSEmtppqgTPSEGTSPQGTPSEETPPQGTPSEGTLPqgTPSQGTPPQGTPSegtppqgTPSQGTPPQGTPS 627
Cdd:PHA03307 313 RASSSSSSSRE------SSSSSTSSSSESSRGAAVSPGPSPSRSP--SPSRPPPPADPSS-------PRKRPRPSRAPSS 377
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 569008203 628 EG-TPSQETLPRETPSEGtpPQGTPSEGTPSQE-TVPQETPP 667
Cdd:PHA03307 378 PAaSAGRPTRRRARAAVA--GRARRRDATGRFPaGRPRPSPL 417
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
544-667 |
1.68e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 45.42 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 544 VSPSEVTPPQGTPSEMTP-PQGTPSEGTSPQGTPSEETPPQG--TPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGT 620
Cdd:pfam05539 162 VSCCKEPKTAVTTSKTTSwPTEVSHPTYPSQVTPQSQPATQGhqTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQR 241
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 569008203 621 PPQGTPSE--GTPSQETLPRETPSEGTPPQGTPSEG----TPSQETVPQETPP 667
Cdd:pfam05539 242 GPSGSPQHppSTTSQDQSTTGDGQEHTQRRKTPPATsnrrSPHSTATPPPTTK 294
|
|
| PRK11633 |
PRK11633 |
cell division protein DedD; Provisional |
494-594 |
1.69e-04 |
|
cell division protein DedD; Provisional
Pssm-ID: 236940 [Multi-domain] Cd Length: 226 Bit Score: 44.22 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 494 VTPP--QGTPSQgtPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPsegtslQVSPSEVTPPQGTPSEMTPPQGTPSEGTS 571
Cdd:PRK11633 55 MMPAatQALPTQ--PPEGAAEAVRAGDAAAPSLDPATVAPPNTPV------EPEPAPVEPPKPKPVEKPKPKPKPQQKVE 126
|
90 100
....*....|....*....|...
gi 569008203 572 PQGTPSEETPPQgtPSEGTLPQG 594
Cdd:PRK11633 127 APPAPKPEPKPV--VEEKAAPTG 147
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
280-726 |
1.69e-04 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 46.22 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 280 LNDADLSSIIHQTSDMQSnlldYENASVTRFKTPSSHNSLHFSPANLSSQSLMASL--------STQV--LQYKQPSFHI 349
Cdd:PTZ00395 60 LVDANENHINTRSSDNNS----CENANMNRDANSSSENVGNANGNNYDNRAHVGRAygagaceqSNQQsnIPIGDPVNHL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 350 SQSYDL--ISEYFLSENIPFQDNQSQDTPSQYTPSQDiQFQDMLAQDISFQEIQSQESPNQDVLYQETPPQETPSQGTPY 427
Cdd:PTZ00395 136 RGHPNFgePRERAEDAAPHAQHNHSGKTNGDNPPTGG-QYHQSGGTSRNHQMMDSNKNCPADALFNETNPSGEHKRNSID 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 428 QDLPYQVLLikDTSP-QGTPYqyiltKEIPFQEtpSQGTLSQESPSQW----TLSKGTPSQGTSPKGTPSQVTPPQGTP- 501
Cdd:PTZ00395 215 GDIPSDIYI--DSQPnEGDVQ-----KTNPWQG--KQGNSATSPPANEnnavTLSCSNDQQRGASSAAESGYAHHRGSNi 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 502 SQGTPSEGTSLQV--SPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTP---PQGTPSEGTSPQ--G 574
Cdd:PTZ00395 286 ASHTPNDNIMHAAnnPLNNTNDAQRNAIQGDLVRGAPNDKNSFDRGNEKTYQIYGGFHDGSPnaaSAGAPFNGLGNQadG 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 575 TPSEETPPQGTPSEGTLPQGTPS---------------------QGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQ 633
Cdd:PTZ00395 366 GHINQVHPDARGAWAGGPHSNASyncaaysnaaqsnaaqsnagfSNAGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYS 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 634 ETLPRETPSEGTPPQGTPSEgTPSQETVPQETPpqklsfqdilTKDRSSQETAYQE----TPFQDLVTQNRPSQDSQYKE 709
Cdd:PTZ00395 446 NPPNSNPPYSNLPYSNTPYS-NAPLSNAPPSSA----------KDHHSAYHAAYQHraanQPAANLPTANQPAANNFHGA 514
|
490
....*....|....*...
gi 569008203 710 TPSQ-EIFFQDTPFQNTP 726
Cdd:PTZ00395 515 AGNSvGNPFASRPFGSAP 532
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
456-656 |
1.72e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 45.69 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 456 PFQETPSQGTLSQESPsqwtLSKGTPSQGTSPKGTPSQvTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGT 535
Cdd:PLN03209 355 PIEEEPPQPKAVVPRP----LSPYTAYEDLKPPTSPIP-TPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEPAQ 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGTSLQVSP----SEVTPPQgTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTP 611
Cdd:PLN03209 430 VEAKKTRPLSPyaryEDLKPPT-SPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDDLKP 508
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 569008203 612 PQG----TPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTP 656
Cdd:PLN03209 509 PTSpspaAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKPRPLSP 557
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
528-663 |
1.77e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 528 EVTPSQGTPSEGTSLQVSPSEVTPPQGTPSemTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPqGTPSQGTPPQGTPS 607
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPA--APAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA-PEHHPKHVAVPDAS 663
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 569008203 608 EGTPPQG---TPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQ 663
Cdd:PRK07764 664 DGGDGWPakaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
479-668 |
1.93e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 1.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 479 GTPSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSE 558
Cdd:PRK07764 417 PAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAA 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 559 mtPPQGTPSEGTSP------------------------------------------------------------------ 572
Cdd:PRK07764 497 --PAAPAAPAGADDaatlrerwpeilaavpkrsrktwaillpeatvlgvrgdtlvlgfstgglarrfaspgnaevlvtal 574
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 573 ---------------------QGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTP 631
Cdd:PRK07764 575 aeelggdwqveavvgpapgaaGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHP 654
|
250 260 270
....*....|....*....|....*....|....*..
gi 569008203 632 SQETLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQ 668
Cdd:PRK07764 655 KHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA 691
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
439-579 |
2.02e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 45.54 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 439 DTSPQGTPYQYIltKEIPFQETPSQGTLSQESPSQwtlskgtpsQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSE 518
Cdd:PRK14971 368 DASGGRGPKQHI--KPVFTQPAAAPQPSAAAAASP---------SPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVP 436
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 569008203 519 VTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGtPSEMTPPQGTPSEGTSPQGTPSEE 579
Cdd:PRK14971 437 VNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLR-PIQEKAEQATGNIKEAPTGTQKEI 496
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
481-703 |
2.18e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.64 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQGTPsqgtpsegtslqvspsevTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGT-PSEM 559
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQP------------------APAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaPARR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TP-PQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQgTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPsEGTPSQETLPR 638
Cdd:PRK12323 427 SPaPEALAAARQASARGPGGAPAPAPAPAAAPAAA-ARPAAAGPRPVAAAAAAAPARAAPAAAPAPAD-DDPPPWEELPP 504
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 569008203 639 ETPSEGtPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDLVTQNRPSQ 703
Cdd:PRK12323 505 EFASPA-PAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRA 568
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
526-667 |
2.32e-04 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 45.04 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 526 PSEVTPSQGTPsEGTSLQVSPsevTPPQGTPSEMTPPQGtpsEGTSPQGTPSEETPPQGTPSEGTlPQGTPSQGTPPQGT 605
Cdd:pfam05539 169 KTAVTTSKTTS-WPTEVSHPT---YPSQVTPQSQPATQG---HQTATANQRLSSTEPVGTQGTTT-SSNPEPQTEPPPSQ 240
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 569008203 606 PSEGTPPQ---GTPSQGTPPQGTPSEGTPSQETLP-----RETPSEGTPPQGTPSEGT------PSQETVPQETPP 667
Cdd:pfam05539 241 RGPSGSPQhppSTTSQDQSTTGDGQEHTQRRKTPPatsnrRSPHSTATPPPTTKRQETgrptprPTATTQSGSSPP 316
|
|
| PTZ00459 |
PTZ00459 |
mucin-associated surface protein (MASP); Provisional |
414-647 |
2.38e-04 |
|
mucin-associated surface protein (MASP); Provisional
Pssm-ID: 185638 [Multi-domain] Cd Length: 291 Bit Score: 44.39 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 414 ETPPQ----ETPSQGTpyQDLPYQVLLIKDTSPQgTPYQYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKG 489
Cdd:PTZ00459 40 KSPPEskglETSSQGT--QDLKGGAAGAKENSPP-LPTEEDDEDVDDDSEEGDDDDGGAEDEEEEKVRGQSGQEGTVALG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 490 TPSQVTPPQGTPSQgtpsegTSLQVSPSEVTPPQG--------TPSEVT----PSQGTPSEGTSLQVSPSEVTPPQGTPs 557
Cdd:PTZ00459 117 SGSTEKKLIGSEKQ------TELSISSAESISPSGsrelnvnlTQTEVEgkkeTDKNTPAVENPLTTGNGENTLPAGIV- 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 558 emtppQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLP 637
Cdd:PTZ00459 190 -----EGNPSPPPPQDGIHSREQDGEGTTSEGQKNVPLPETAATPQSHHDKGSEGTGEDTKATTVTANTTDTTNTQNSDG 264
|
250
....*....|
gi 569008203 638 RETPSEGTPP 647
Cdd:PTZ00459 265 STAVSHTTSP 274
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
501-758 |
2.58e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 44.95 E-value: 2.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 501 PSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGT------SLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQG 574
Cdd:pfam17823 67 PAPVTLTKGTSAAHLNSTEVTAEHTPHGTDLSEPATREGAadgaasRALAAAASSSPSSAAQSLPAAIAALPSEAFSAPR 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 575 TPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTpPQGTPSEG 654
Cdd:pfam17823 147 AAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAAT-ATGHPAAG 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 655 TPSQEtVPQETPPQKLSFQDILTKDRSSQET--AYQETPFQDLVTQNRPSQDSQykeTPSqeiffqdtPFQNTPSQNIQY 732
Cdd:pfam17823 226 TALAA-VGNSSPAAGTVTAAVGTVTPAALATlaAAAGTVASAAGTINMGDPHAR---RLS--------PAKHMPSDTMAR 293
|
250 260
....*....|....*....|....*.
gi 569008203 733 QDILSQDKISQGSQTQNSVSQEMASS 758
Cdd:pfam17823 294 NPAAPMGAQAQGPIIQVSTDQPVHNT 319
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
483-728 |
2.65e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 45.41 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 483 QGTSPKGTPSQVTPPQGTPSQGTPSEGtslqvSPSEVTPPQGTPSEVTPSQGTPSEgtsLQVSPS--EVTPPQGTPSEMT 560
Cdd:pfam09770 105 QQPAARAAQSSAQPPASSLPQYQYASQ-----QSQQPSKPVRTGYEKYKEPEPIPD---LQVDASlwGVAPKKAAAPAPA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 561 P-PQGTPSEG-------------------TSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGT 620
Cdd:pfam09770 177 PqPAAQPASLpapsrkmmsleeveaamraQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQH 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 621 PPQGTPsegtPSQetLPRETPSEGTPPQgtPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQetayQETPFQDLVTQNR 700
Cdd:pfam09770 257 PGQGHP----VTI--LQRPQSPQPDPAQ--PSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSA----ARVGYPQNPQPGV 324
|
250 260
....*....|....*....|....*...
gi 569008203 701 PSQDSQYkETPSQEIFFQDTPFQNTPSQ 728
Cdd:pfam09770 325 QPAPAHQ-AHRQQGSFGRQAPIITHPQQ 351
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
516-662 |
2.82e-04 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 45.00 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 516 PSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGT 595
Cdd:pfam09606 60 QQQPQGGQGNGGMGGGQQGMPDPINALQNLAGQGTRPQMMGPMGPGPGGPMGQQMGGPGTASNLLASLGRPQMPMGGAGF 139
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 569008203 596 PSQGTP-PQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVP 662
Cdd:pfam09606 140 PSQMSRvGRMQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
217-627 |
3.00e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.14 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 217 SSTPKTIQQKSDKGTSFMYVPEEQEATPPLSPEQeiKLNALPPPLTP-YPSENIPSQKDSTTDHLNDADLSSIIHQTSDM 295
Cdd:pfam03154 160 SSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQ--AATAGPTPSAPsVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTL 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 296 QSNLLDYENASVTRFKTPSShnslhfsPANLSSQSL-MASLSTQVlqykQPSFHISQSydliSEYFLSENIPFQ--DNQS 372
Cdd:pfam03154 238 HPQRLPSPHPPLQPMTQPPP-------PSQVSPQPLpQPSLHGQM----PPMPHSLQT----GPSHMQHPVPPQpfPLTP 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 373 QDTPSQYTPSQDIQFQDMLAQDISFQEIQSQESPNQDVLYQETPPQETPsqgTPYQDLPYQVLLIKDTSPQGTPYQYILT 452
Cdd:pfam03154 303 QSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLS---MPHIKPPPTTPIPQLPNPQSHKHPPHLS 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 453 KEIPFQetpsqgtLSQESPSQWTLSkgtPSQGTSPKGTPSQVTPPQGTPSQGTpsegtslQVSPSEVTPPQGTPSEVTPS 532
Cdd:pfam03154 380 GPSPFQ-------MNSNLPPPPALK---PLSSLSTHHPPSAHPPPLQLMPQSQ-------QLPPPPAQPPVLTQSQSLPP 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 533 QGT--PSEGTSLQVSPSEVTPPQ----GTPSEMTPPQGTPSegTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTP 606
Cdd:pfam03154 443 PAAshPPTSGLHQVPSQSPFPQHpfvpGGPPPITPPSGPPT--STSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIK 520
|
410 420
....*....|....*....|.
gi 569008203 607 SEGTPPQGTPSQGTPPQGTPS 627
Cdd:pfam03154 521 EEALDEAEEPESPPPPPRSPS 541
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
504-628 |
4.20e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.38 E-value: 4.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 504 GTPSEGTSLQVSP--SEVTPPQGTPSEVTPSQGTPSEGTSLQ-VSPSEVTPPQGTPSEMTPPQGTPSEgTSPQGTPSEET 580
Cdd:PRK14971 369 ASGGRGPKQHIKPvfTQPAAAPQPSAAAAASPSPSQSSAAAQpSAPQSATQPAGTPPTVSVDPPAAVP-VNPPSTAPQAV 447
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 569008203 581 PPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSE 628
Cdd:PRK14971 448 RPAQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTGTQKE 495
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
496-617 |
4.29e-04 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 44.18 E-value: 4.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 496 PPQGTPSQGTPSEGTSLQVSPSEVTP--PQGTPSEV-TPSQGTPsegtslqvspsevTPPQGTPSEMTPPQGTPSEGTSP 572
Cdd:PHA03291 167 PAEGTLAAPPLGEGSADGSCDPALPLsaPRLGPADVfVPATPRP-------------TPRTTASPETTPTPSTTTSPPST 233
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 569008203 573 QGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGtpsEGTPPQGTPS 617
Cdd:PHA03291 234 TIPAPSTTIAAPQAGTTPEAEGTPAPPTPGGG---EAPPANATPA 275
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
560-668 |
4.43e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.59 E-value: 4.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TPPQGTPSEGTSPQGTPSEetPPQGTPSEGTLPQGTPSQgTPPQGTPSEGTPPQGTPSQGT--PPQGTPSEGTPSQETLP 637
Cdd:PRK07764 392 GAPAAAAPSAAAAAPAAAP--APAAAAPAAAAAPAPAAA-PQPAPAPAPAPAPPSPAGNAPagGAPSPPPAAAPSAQPAP 468
|
90 100 110
....*....|....*....|....*....|.
gi 569008203 638 RETPSEGTPPQGTPSEGTPSQETVPQETPPQ 668
Cdd:PRK07764 469 APAAAPEPTAAPAPAPPAAPAPAAAPAAPAA 499
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
549-646 |
4.83e-04 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 44.23 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 549 VTPPQGTPSEMTPPQGTPSEGT-SPQGTPSEETPPQGTPSEGTLP-QGTPSQGTPPQGTPSEGTPPqGTPSQGTPPQGTP 626
Cdd:PHA03264 253 VVPPYFEESKGYEPPPAPSGGSpAPPGDDRPEAKPEPGPVEDGAPgRETGGEGEGPEPAGRDGAAG-GEPKPGPPRPAPD 331
|
90 100
....*....|....*....|...
gi 569008203 627 S---EGTPSQETLPRETPSEGTP 646
Cdd:PHA03264 332 AdrpEGWPSLEAITFPPPTPATP 354
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
398-669 |
5.03e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 5.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 398 QEIQSQESPNQDvLYQETPPQETPSQGTPYQDLPYQVLLIKDTSPQGTPYQYILTKEIPFQeTPSQGTLSQESPSQWTLS 477
Cdd:pfam03154 240 QRLPSPHPPLQP-MTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFP-LTPQSSQSQVPPGPSPAA 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 478 KGTPSQgtSPKGTPSQVTPPQGTPSQGTPSEGTSL---QVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQG 554
Cdd:pfam03154 318 PGQSQQ--RIHTPPSQSQLQSQQPPREQPLPPAPLsmpHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 555 -----------TPSEMTPP--------QGTPSEGTSPQGTPSEETPPQGT-----------PSEGTLPQGTPSQGTPPQG 604
Cdd:pfam03154 396 lkplsslsthhPPSAHPPPlqlmpqsqQLPPPPAQPPVLTQSQSLPPPAAshpptsglhqvPSQSPFPQHPFVPGGPPPI 475
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 569008203 605 TPSEGtPPQGTPSQGTPPQGTPSEGTPSQETLPrETPSEGTPPQGTPSEGTPSQETVPQETPPQK 669
Cdd:pfam03154 476 TPPSG-PPTSTSSAMPGIQPPSSASVSSSGPVP-AAVSCPLPPVQIKEEALDEAEEPESPPPPPR 538
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
398-646 |
7.12e-04 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 43.84 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 398 QEIQSQESPNQDVL-YQETPPQETPS--QGTPYQDLPYQVLLIKDTSPQGTPYQyiLTKEIPfQETPSQGTLSQESPSQW 474
Cdd:pfam09606 244 QQQQPQQQGQQSQLgMGINQMQQMPQgvGGGAGQGGPGQPMGPPGQQPGAMPNV--MSIGDQ-NNYQQQQTRQQQQQQGG 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 475 TLSKGTPSQGTSPKGTPSQVTPpqgTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSqGTPSEGTSLQvspsEVTPPQG 554
Cdd:pfam09606 321 NHPAAHQQQMNQSVGQGGQVVA---LGGLNHLETWNPGNFGGLGANPMQRGQPGMMSS-PSPVPGQQVR----QVTPNQF 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 555 TPSemTPPQGTPSEGTsPQGTPSEETPPQGTPSEGTLPQGTPSqgtPPQGTPSEGTPPQGTPSQ--GTPPQGT-PSEGTP 631
Cdd:pfam09606 393 MRQ--SPQPSVPSPQG-PGSQPPQSHPGGMIPSPALIPSPSPQ---MSQQPAQQRTIGQDSPGGslNTPGQSAvNSPLNP 466
|
250
....*....|....*
gi 569008203 632 SQETLPRETPSEGTP 646
Cdd:pfam09606 467 QEEQLYREKYRQLTK 481
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
456-662 |
7.88e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 43.68 E-value: 7.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 456 PFQETPSQGTLSQESPSqwtlSKGTPSQGTSPKGTPSQVTPPqgtPSQGTPSEGTSLQVSPSEVTPPQgTPSEVTPSQGT 535
Cdd:PRK07003 427 PAAPAPPATADRGDDAA----DGDAPVPAKANARASADSRCD---ERDAQPPADSGSASAPASDAPPD-AAFEPAPRAAA 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPqgTPSEETPP------------------QGTPSEGTLPQGTPS 597
Cdd:PRK07003 499 PSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPP--TPAAAAPAaraggaaaaldvlrnagmRVSSDRGARAAAAAK 576
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569008203 598 QGTPPQGTPSEGTPPQG--TPSQGTPPQGTPSEGTPSQETlPRETPSEGTPPqgtPSEGTPSQETVP 662
Cdd:PRK07003 577 PAAAPAAAPKPAAPRVAvqVPTPRARAATGDAPPNGAARA-EQAAESRGAPP---PWEDIPPDDYVP 639
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
532-669 |
7.97e-04 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 41.56 E-value: 7.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 532 SQGTPSEGTSLQVSPSEVTPPQGT-PSEMTPPQGTPSEGTSPQGTPSEETP-------PQGTPSEG--TLPQGTPSQGTP 601
Cdd:pfam15240 15 SAQSSSEDVSQEDSPSLISEEEGQsQQGGQGPQGPPPGGFPPQPPASDDPPgppppggPQQPPPQGgkQKPQGPPPQGGP 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569008203 602 -PQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQEtlpretpsEGTPPQGTPSEGTPSQETVPQETPPQK 669
Cdd:pfam15240 95 rPPPGKPQGPPPQGGNQQQGPPPPGKPQGPPPQG--------GGPPPQGGNQQGPPPPPPGNPQGPPQR 155
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
551-663 |
8.32e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 43.52 E-value: 8.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 551 PPQGTPSEMTPPQGTPSEGTSPQG--TPSEETPPQGTPSEGTLPQgTPSQGTPPqGTPSEGTPPQGTPSQgtpPQGTPSE 628
Cdd:PRK14959 389 PASGGAATIPTPGTQGPQGTAPAAgmTPSSAAPATPAPSAAPSPR-VPWDDAPP-APPRSGIPPRPAPRM---PEASPVP 463
|
90 100 110
....*....|....*....|....*....|....*
gi 569008203 629 GTPSQETLPRETPsegtPPQGTPSEGTPSQETVPQ 663
Cdd:PRK14959 464 GAPDSVASASDAP----PTLGDPSDTAEHTPSGPR 494
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
514-604 |
9.37e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 43.26 E-value: 9.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 514 VSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQ 593
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVDE 440
|
90
....*....|.
gi 569008203 594 GTPSQGTPPQG 604
Cdd:PRK14950 441 KPKYTPPAPPK 451
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
485-668 |
9.84e-04 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 9.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 485 TSPKGTPSQVTP-PQGTPSQGTPSEGtsLQVSPSevtpPQGTPSEVTPSQGTPSEGTSLQVSPSEVTPPQGTPSEMTPPQ 563
Cdd:NF033839 273 TKFKKGLTQDTPkEPGNKKPSAPKPG--MQPSPQ----PEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQ 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 564 -GTPSEGTSPQ-GTPSEETPPQgtpSEGTLPQGTPSQGTP-PQGTPSEGTP-PQGTPSQGTP-PQGTPSEGTPSQETLP- 637
Cdd:NF033839 347 lETPKPEVKPQpEKPKPEVKPQ---PEKPKPEVKPQPETPkPEVKPQPEKPkPEVKPQPEKPkPEVKPQPEKPKPEVKPq 423
|
170 180 190
....*....|....*....|....*....|...
gi 569008203 638 RETPSEGTPPQG-TPS-EGTPSQETVPQETPPQ 668
Cdd:NF033839 424 PEKPKPEVKPQPeKPKpEVKPQPEKPKPEVKPQ 456
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
562-667 |
1.03e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 43.13 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 562 PQGTPSEGTSPQGTPSeeTPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQG-TPSQGTP----PQGTPSEGTPSQETl 636
Cdd:PRK14959 363 PRLMPVESLRPSGGGA--SAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGmTPSSAAPatpaPSAAPSPRVPWDDA- 439
|
90 100 110
....*....|....*....|....*....|....*...
gi 569008203 637 PRETPSEGTPPQG-------TPSEGTPSQETVPQETPP 667
Cdd:PRK14959 440 PPAPPRSGIPPRPaprmpeaSPVPGAPDSVASASDAPP 477
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
521-634 |
1.06e-03 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 43.02 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 521 PPQGTPSEvTPSQGTPSEGT--------SLQVSPSEVTPPqGTPsemTPPQGTPsegtspqgTPSEETPPQGTPSEGTLP 592
Cdd:PHA03291 167 PAEGTLAA-PPLGEGSADGScdpalplsAPRLGPADVFVP-ATP---RPTPRTT--------ASPETTPTPSTTTSPPST 233
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 569008203 593 QGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQG--TPSEGTPSQE 634
Cdd:PHA03291 234 TIPAPSTTIAAPQAGTTPEAEGTPAPPTPGGGeaPPANATPAPE 277
|
|
| Treacle |
pfam03546 |
Treacher Collins syndrome protein Treacle; |
481-712 |
1.15e-03 |
|
Treacher Collins syndrome protein Treacle;
Pssm-ID: 460967 [Multi-domain] Cd Length: 531 Bit Score: 43.14 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTP---SQGTPSEGTSLQVSPSeVTPPQGTPS 557
Cdd:pfam03546 4 TPGKAGPAATQAKAGKPEEDSESSSEEESDSEEETPAAKTPLQAKPSGKTPqvrAASAPAKESPRKGAPP-VPPGKTGPA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 558 EMTPPQGTP---SEGTSPQGTPSEETPPQGTPSegTLPQGTPSQGTPPQGTPSEgTPPQGTPSQGTPPQGTPSEGTpsqe 634
Cdd:pfam03546 83 AAQAQAGKPeedSESSSEESDSDGETPAAATLT--TSPAQVKPLGKNSQVRPAS-TVGKGPSGKGANPAPPGKAGS---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 635 TLPRETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETPFQDL------VTQNRPSQDSQYK 708
Cdd:pfam03546 156 AAPLVQVGKKEEDSESSSEESDSEGEAPPAATQAKPSGKILQVRPASGPAKGAAPAPPQKAgpvatqVKAERSKEDSESS 235
|
....
gi 569008203 709 ETPS 712
Cdd:pfam03546 236 EESS 239
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
476-666 |
1.27e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 43.13 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 476 LSKGTPSQGTSPKGTPSqvTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTP-SEVTPSQGTPSegtslqvspseVTPPQG 554
Cdd:PRK14959 362 LPRLMPVESLRPSGGGA--SAPSGSAAEGPASGGAATIPTPGTQGPQGTAPaAGMTPSSAAPA-----------TPAPSA 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 555 TPSemtppqgtPSegtspqgTPSEETPPqGTPSEGTLPQGTPSQgtpPQGTPSEGTPPQGTPSQGTPPQ-GTPSEGTPSQ 633
Cdd:PRK14959 429 APS--------PR-------VPWDDAPP-APPRSGIPPRPAPRM---PEASPVPGAPDSVASASDAPPTlGDPSDTAEHT 489
|
170 180 190
....*....|....*....|....*....|...
gi 569008203 634 ETLPRETPSEGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PRK14959 490 PSGPRTWDGFLEFCQGRNGQGGRLATVLRQATP 522
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
502-667 |
1.71e-03 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 40.41 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 502 SQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGtslqvsPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETP 581
Cdd:pfam15240 15 SAQSSSEDVSQEDSPSLISEEEGQSQQGGQGPQGPPPG------GFPPQPPASDDPPGPPPPGGPQQPPPQGGKQKPQGP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 582 PqgtPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEgtPPQGTPSEgtPSQETV 661
Cdd:pfam15240 89 P---PQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQGPPPQGGGPPPQGGNQQGPPPPPPG--NPQGPPQR--PPQPGN 161
|
....*.
gi 569008203 662 PQETPP 667
Cdd:pfam15240 162 PQGPPQ 167
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
481-668 |
2.22e-03 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 42.30 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 481 PSQGTSPKGTPSQVTPPQGTPSQ--GTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGT----PSEGTSLQVSPSEVTPPQG 554
Cdd:pfam09606 90 AGQGTRPQMMGPMGPGPGGPMGQqmGGPGTASNLLASLGRPQMPMGGAGFPSQMSRVgrmqPGGQAGGMMQPSSGQPGSG 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 555 TPSEMTPPQGtPSEGTSPQGTPSEETPPQGTPSEGTLPQG-----TPSQGTPPQGTPSEGTPPQG-------TPSQGTPP 622
Cdd:pfam09606 170 TPNQMGPNGG-PGQGQAGGMNGGQQGPMGGQMPPQMGVPGmpgpaDAGAQMGQQAQANGGMNPQQmggapnqVAMQQQQP 248
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 569008203 623 QGTPSEGTPSQETLPRETPSEGTP---PQGTPSEGTPSQETVPQETPPQ 668
Cdd:pfam09606 249 QQQGQQSQLGMGINQMQQMPQGVGggaGQGGPGQPMGPPGQQPGAMPNV 297
|
|
| PHA03291 |
PHA03291 |
envelope glycoprotein I; Provisional |
561-667 |
2.46e-03 |
|
envelope glycoprotein I; Provisional
Pssm-ID: 223033 [Multi-domain] Cd Length: 401 Bit Score: 41.86 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 561 PPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRET 640
Cdd:PHA03291 167 PAEGTLAAPPLGEGSADGSCDPALPLSAPRLGPADVFVPATPRPTPRTTASPETTPTPSTTTSPPSTTIPAPSTTIAAPQ 246
|
90 100
....*....|....*....|....*...
gi 569008203 641 PSEGTPPQGTPSEGTP-SQETVPQETPP 667
Cdd:PHA03291 247 AGTTPEAEGTPAPPTPgGGEAPPANATP 274
|
|
| PHA03369 |
PHA03369 |
capsid maturational protease; Provisional |
540-653 |
3.24e-03 |
|
capsid maturational protease; Provisional
Pssm-ID: 223061 [Multi-domain] Cd Length: 663 Bit Score: 41.52 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 540 TSLQVSPSEVTPPQGTPSEMTPPQGTPsegtspqgTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQG 619
Cdd:PHA03369 350 TASLTAPSRVLAAAAKVAVIAAPQTHT--------GPADRQRPQRPDGIPYSVPARSPMTAYPPVPQFCGDPGLVSPYNP 421
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 569008203 620 TPP----QGTPSEGTPSQETLPRETPSE--GTPPQGTPSE 653
Cdd:PHA03369 422 QSPgtsyGPEPVGPVPPQPTNPYVMPISmaNMVYPGHPQE 461
|
|
| CytochromB561_N |
pfam09786 |
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ... |
417-633 |
3.27e-03 |
|
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.
Pssm-ID: 462899 Cd Length: 579 Bit Score: 41.73 E-value: 3.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 417 PQETPSQGTPYQdlpyQVLL-IK-------DTSPQGTPyqyiltKEIPFQETPSQgTLSQESPSQwtlskgTPSQGTSPK 488
Cdd:pfam09786 97 GTKTPSRLTNQQ----LGLLgLKpndssfvTTHRKKPP------KSKSSPQSPSP-VLVPLHQSV------SPSSSESRK 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 489 GTPSqvTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPsEVTPPQGTPS---EMTPPQGT 565
Cdd:pfam09786 160 GGDK--SPAGSGKKLRSFSTSSKSPASPSVYLRGSPVPLNSSPLPSDRNYENSVQSSP-EIDSAVSTPWsrkRATIGKEI 236
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 569008203 566 PSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPP----QGTPSQGTPPQGTPSEGTPSQ 633
Cdd:pfam09786 237 RTEKMLERFLAEVDEKITESAFGKASPSNVSGSANRSGSTRSTPLRSvrmsPGSQKFTTPPKKGEGDLPSPM 308
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
536-695 |
3.38e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 41.00 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 536 PSEGTSLQVSPSEVTPPQGTPSeMTPPQGTPSEgTSPqgTPSEETPPQGTPsegTLPqgtPSQGTPPQGTPSEGTPPQGT 615
Cdd:PHA02682 76 PSGQSPLAPSPACAAPAPACPA-CAPAAPAPAV-TCP--APAPACPPATAP---TCP---PPAVCPAPARPAPACPPSTR 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 616 PSQGTPPqgtpsegTPSQETLPRETPS---EGTPPQGTPSEGTPSQETVPQETP------PQKLSFQDILTKDRSSQETA 686
Cdd:PHA02682 146 QCPPAPP-------LPTPKPAPAAKPIflhNQLPPPDYPAASCPTIETAPAASPvlepriPDKIIDADNDDKDLIKKELA 218
|
....*....
gi 569008203 687 YQETPFQDL 695
Cdd:PHA02682 219 DIADSVRDL 227
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
489-691 |
3.58e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 3.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 489 GTPSQVTPPQGT-PSQGTPSEGTSLQVSPSEVTPPqgTPSEVTPSQgTPSEGTSLQVSPSEVT----------PPQGTPS 557
Cdd:PHA03247 2476 GAPVYRRPAEARfPFAAGAAPDPGGGGPPDPDAPP--APSRLAPAI-LPDEPVGEPVHPRMLTwirgleelasDDAGDPP 2552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 558 EMTPPQGTPSegTSPQGTPSEETPPQgtPSEGTLPQGTPSQGTPPQ-GTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETL 636
Cdd:PHA03247 2553 PPLPPAAPPA--APDRSVPPPRPAPR--PSEPAVTSRARRPDAPPQsARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPP 2628
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 569008203 637 PRETPSEGTPPQGTPSEGTPSQETVPQETPPQKLSFQDILTKDRSSQETAYQETP 691
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRP 2683
|
|
| PHA03418 |
PHA03418 |
hypothetical E4 protein; Provisional |
506-654 |
4.47e-03 |
|
hypothetical E4 protein; Provisional
Pssm-ID: 177646 [Multi-domain] Cd Length: 230 Bit Score: 40.11 E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 506 PSEGTSLQVSPSEVTPPQGTPSEVTPSQGTPSEGTSLQVSPSEVTP----PQGTPSEMTPP--------QGTPSEGTSPQ 573
Cdd:PHA03418 14 PIDTVNLANGRSELIRKLCLPLLPAPHHPNPQEDPDKNPSPPPDPPltprPPAQPNGHNKPpvtkqpggEGTEEDHQAPL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 574 GTPSEETPPQGTPSEGTLPQGTPSQGT-----------PPQGTPSEgtPPQGTPSQG-TPPQG------TPSEGTPSQET 635
Cdd:PHA03418 94 AADADDDPRPGKRSKADEHGPAPGRAAlapfkldldqdPLHGDPDP--PPGATGGQGeEPPEGgeesqpPLGEGEGAVEG 171
|
170
....*....|....*....
gi 569008203 636 LPRETPSegtPPQGTPSEG 654
Cdd:PHA03418 172 HPPPLPP---APEPKPHNG 187
|
|
| PHA03309 |
PHA03309 |
transcriptional regulator ICP4; Provisional |
567-709 |
5.50e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain] Cd Length: 2033 Bit Score: 40.99 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 567 SEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQgTPPQGTP---------SEGTPPQGTPSQGTPPQGTPSEGTPSQeTLP 637
Cdd:PHA03309 1816 SSSSSSSSSSSSSSSPSSRPSRSATPSLSPSP-SPPRRAPvdrsrsgrrRERDRPSANPFRWAPRQRSRADHSPDG-TAP 1893
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569008203 638 RETP--SEGTPPQGTPSEGTPSQETVPQETPPQKlSFQDILTKDrSSQETAYQETPFQdlVTQNRPSQDSQYKE 709
Cdd:PHA03309 1894 GDAPlnLEDGPGRGRPIWTPSSATTLPSRSGPED-SVDETETED-SAPPARLAPSPLE--TSRAEDSEDSEYPE 1963
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
369-681 |
5.57e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 40.86 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 369 DNQSQDTPSQYTPSQDIQFQDMLAQDISFQEIQ-SQESPNQDVLYQETPPQETpsqgtpYQDLPYQVllikDTSPQGTPY 447
Cdd:PRK14949 499 NPSVTDTQVDDTSASNNSAADNTVDDNYSAEDTlESNGLDEGDYAQDSAPLDA------YQDDYVAF----SSESYNALS 568
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 448 QYILTKEIPFQETPSQGTLSQESPSQWTLSKGTPSQGTSPKGTPSQVTPPQGTPSQG----TPSEGTSLQVSPS--EVTP 521
Cdd:PRK14949 569 DDEQHSANVQSAQSAAEAQPSSQSLSPISAVTTAAASLADDDILDAVLAARDSLLSDldalSPKEGDGKKSSADrkPKTP 648
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 522 PQGTPSeVTPSQGTPSegtslqvSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPqgtpsegtlPQGTPSQgTP 601
Cdd:PRK14949 649 PSRAPP-ASLSKPASS-------PDASQTSASFDLDPDFELATHQSVPEAALASGSAPAPP---------PVPDPYD-RP 710
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 602 PQGTPSEGTPPQGTPSQGTPPQGTPSEGTPSQETLPRETPSEGTPPQGTPSEGTPSQETVPQET--PPQKLSFQDILTKD 679
Cdd:PRK14949 711 PWEEAPEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQPQVQAEAQSPASTTALTQTssEVQDTELNLVLLSS 790
|
..
gi 569008203 680 RS 681
Cdd:PRK14949 791 GS 792
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
473-760 |
6.67e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 40.67 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 473 QWTLSKGTPSQGTSPKGT-PSQVTPPQGTPSQGTPSEGTSLQVSPSEVT-----------PPQGTPSEVTPSQGTPSEGT 540
Cdd:pfam05109 365 KWTLTSGTPSGCENISGAfASNRTFDITVSGLGTAPKTLIITRTATNATttthkvifskaPESTTTSPTLNTTGFAAPNT 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 541 SLQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQ--GTPSEETPPqgTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQ 618
Cdd:pfam05109 445 TTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTpaGTTSGASPV--TPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATS 522
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 619 GTPPQGTPSEGTPSqETLPRETPSEG-TPPQGTPSEGTPSQET-VPQETPPqklsfqdilTKDRSSQETAYQeTPFQDLV 696
Cdd:pfam05109 523 PTPAVTTPTPNATS-PTLGKTSPTSAvTTPTPNATSPTPAVTTpTPNATIP---------TLGKTSPTSAVT-TPTPNAT 591
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569008203 697 TQNRPSQDSQYKETPSQEIFFQDTPFQNTPSQNIQYQDILSQDKISQGSQTQNSVSQEMASSDL 760
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETL 655
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
489-666 |
6.73e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 40.34 E-value: 6.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 489 GTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPS---EVTPSQGTPSEGTSLQVSPSEVTPPQG------TPSEM 559
Cdd:PHA03169 55 GPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQGGPSgsgSESVGSPTPSPSGSAEELASGLSPENTsgsspeSPASH 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 560 TPPQGTPSEGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGT-PPQGTPSE-----GTPPQG-TPSQGTPPQGTPSEGTPS 632
Cdd:PHA03169 135 SPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPeEPEPPTSEpepdsPGPPQSeTPTSSPPPQSPPDEPGEP 214
|
170 180 190
....*....|....*....|....*....|....*.
gi 569008203 633 QETLPRETPS--EGTPPQGTPSEGTPSQETVPQETP 666
Cdd:PHA03169 215 QSPTPQQAPSpnTQQAVEHEDEPTEPEREGPPFPGH 250
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
518-653 |
9.44e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.14 E-value: 9.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 518 EVTPPQGTPSEVTPSQGTPSEGTslQVSPSEVTPPQGTPSEMTPPQGTPSEGTSPQGTPSEETPPQGTPSEgtlpqgTPS 597
Cdd:PRK14971 368 DASGGRGPKQHIKPVFTQPAAAP--QPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVP------VNP 439
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 598 QGTPPQGTPsegtPPQGTPSQGTPPQGTPSEG----TPSQETLPRETPSEGTPPQGTPSE 653
Cdd:PRK14971 440 PSTAPQAVR----PAQFKEEKKIPVSKVSSLGpstlRPIQEKAEQATGNIKEAPTGTQKE 495
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
482-632 |
9.80e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 40.22 E-value: 9.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569008203 482 SQGTSPKGTPSQVTPPQGTPSQGTPSEGTSLQVSPSEVTPPQGTPSEVTPSQG---TPSEGTSLQVSPSEVTPPQGTPSE 558
Cdd:PRK07003 393 ASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGdapVPAKANARASADSRCDERDAQPPA 472
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569008203 559 MTPPQGTPSeGTSPQGTPSEETPPQGTPSEGTLPQGTPSQGTPPQGTPSEGTPPQGTPSQGTPPqgTPSEGTPS 632
Cdd:PRK07003 473 DSGSASAPA-SDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPP--TPAAAAPA 543
|
|
| |
