|
Name |
Accession |
Description |
Interval |
E-value |
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
445-680 |
3.82e-91 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 283.11 E-value: 3.82e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 445 ITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGhySFPWAHTHLWLVDERCVPLSDPDSNFQG 524
Cdd:TIGR01198 1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ--PLDWSRIHLFLGDERYVPLDHADSNTGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 525 LQAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVAN---SSFDLVLLGMGTDGHTASLFPQSPTGLDG 601
Cdd:TIGR01198 79 AREALLDRVAIPASNIHPMPTEL-----SDIEEAAELYEQELAAAFQPivfPVFDLLLLGMGPDGHTASLFPHTPALQET 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 602 DQLV-VLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPlSGQLVWYMDYEAFLG 680
Cdd:TIGR01198 154 ERLVtVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLH-SGKTLWLLDYAAARK 232
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
447-671 |
3.76e-83 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 261.79 E-value: 3.76e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 447 AWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQ 526
Cdd:pfam01182 1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLDWSRVHVFWGDERCVPPDDPDSNYGMAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 527 AHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVANSS---FDLVLLGMGTDGHTASLFPQSPTGLDGDQ 603
Cdd:pfam01182 81 EALLSHVPIPASNVHPIPASA-----ADPEEAAAAYEAELRELLPDLElpvFDLVLLGMGPDGHTASLFPGSPALEETDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 604 LVV-LTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV-GHEPKKWPISGVVPLSGQLVW 671
Cdd:pfam01182 156 LVVaVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA---LRRAlAGDPDPLPAALVRPGAGETVW 222
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
450-673 |
1.36e-78 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 249.79 E-value: 1.36e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 450 EELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGhYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHL 529
Cdd:cd01400 1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLAAA-PALDWSKVHVFLGDERCVPPDDPDSNYRLAREAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 530 LQHVRVPYYNIHPMPVHLHqrlcaeEDQGAQTYASEISALVANS-SFDLVLLGMGTDGHTASLFPQSP-TGLDGDQLVVL 607
Cdd:cd01400 80 LSHVAIPAANIHPIPTELG------PEDAAAAYEKELRALFGGVpPFDLVLLGMGPDGHTASLFPGHPaLLEETDRLVVA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568930405 608 TE-SPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSGQLVWYM 673
Cdd:cd01400 154 VTdSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEA---LKRAlaGPDPEELPAARVLPRPGEVLWFL 219
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
449-677 |
2.56e-56 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 191.91 E-value: 2.56e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 449 PEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYS--FPWAHTHLWLVDERC-VPLSDPDSNFQGL 525
Cdd:COG0363 10 AEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEggLDWSRVHVFNLDEYVgLPPDHPQSNRRFM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 526 QAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLV 605
Cdd:COG0363 90 REALLDHVDIPPENIHIPDGEA-----EDPEAAAARYEALIAEA---GGIDLQLLGIGEDGHIAFNFPGSPFLSETDRVV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 606 VLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSgQLVW 671
Cdd:COG0363 162 TLDESTRQanarffgsipkvPPQAITLGIPTIMKAREILLLATGENKAEA---VAAAleGPVTEEVPASILQGHP-NVTW 237
|
....*.
gi 568930405 672 YMDYEA 677
Cdd:COG0363 238 FLDEAA 243
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
137-393 |
1.07e-50 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 178.02 E-value: 1.07e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSS----AILGQYQAysGQVRREL 212
Cdd:pfam02781 34 GRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAED-IRDEKVKVLRSLRPITPEDvednVVRGQYGA--GWIGGEP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 213 QK---------PDgfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwVP-----EQ 278
Cdd:pfam02781 111 VPgyreeegvpPD---SRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQFKD-----------VPhnlfrDP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 279 SRCLPQQIIFYIGHGElghpAILVSRNLFKpslptqkwkevqdqPGLRLFGRPLS---DYYAYRPVREQDAYSTLLSHIF 355
Cdd:pfam02781 177 GTLPPNELVIRIQPDE----GIYLKFNAKV--------------PGLGMRLRPVEldfSYSDRFGERIPEAYERLLLDVM 238
|
250 260 270
....*....|....*....|....*....|....*...
gi 568930405 356 HCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGG 393
Cdd:pfam02781 239 RGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPPYPAG 276
|
|
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
137-393 |
6.15e-35 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 139.89 E-value: 6.15e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAILGQYQAYS-GQVRRELQK- 214
Cdd:PTZ00309 275 GRGGYFDSYGIIRDVMQNHLLQILALLAMEKPVSLSAED-IRDEKVKVLKCIEPIKMEECVLGQYTASAdGSIPGYLEDe 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 215 --PDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwVPEqsrclpqqIIFYigh 292
Cdd:PTZ00309 354 gvPKD--STTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKG-----------VDE--------FRPS--- 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 293 GELGHPAILVSRnlFKPSlPTQKWKEVQDQPGLrlfGRPLS------DYYAYRPVREQDAYSTLLSHIFHCRKESFITTE 366
Cdd:PTZ00309 410 GDDTQRNELVIR--AQPS-EAMYLKITAKVPGL---SNDLHqteldlTYKTRYNVRLPDAYERLILDALLGDSTNFVRKD 483
|
250 260
....*....|....*....|....*....
gi 568930405 367 NLLASWVFWTPLLDSL-AFEV-PRPYPGG 393
Cdd:PTZ00309 484 ELDVAWRIFTPLLHQIdRGEVkPEPYPFG 512
|
|
| PLN02360 |
PLN02360 |
probable 6-phosphogluconolactonase |
450-677 |
1.23e-30 |
|
probable 6-phosphogluconolactonase
Pssm-ID: 166001 [Multi-domain] Cd Length: 268 Bit Score: 121.12 E-value: 1.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 450 EELISKLASDIEAAAVQAVRHFGKFHLALSGGSSpIALFQQLATGHY--SFPWAHTHLWLVDERCVPLSDPDSNFQGLQA 527
Cdd:PLN02360 20 DELSTDLAEYIAELSEASVKERGVFAIALSGGSL-ISFMGKLCEAPYnkTVDWAKWYIFWADERVVAKNHADSNYKLAKD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 528 HLLQHVRVPYYNIHPmpvhLHQRLCAEEdqGAQTYASEISALVANSS-----------FDLVLLGMGTDGHTASLFPQSP 596
Cdd:PLN02360 99 GLLSKVPVVPSHVYS----INDTVTAEE--AATDYEFAIRQLVKTRTigvsdisdcpkFDLILLGMGSDGHVASLFPNHP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 597 T-GLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTL-VSRVGHEP--KKWPISGVVPLSGQLVWY 672
Cdd:PLN02360 173 AlEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLaIDDVTEGPdaPSLPARMVQPTKGKLVWF 252
|
....*
gi 568930405 673 MDYEA 677
Cdd:PLN02360 253 LDKPA 257
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
137-393 |
3.94e-28 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 118.58 E-value: 3.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPlNISSSAAVLQHKLWAFQALRGLQK--SSAILGQYQAysGQVRRElQK 214
Cdd:TIGR00871 221 GRGGYYDKSGALRDMVQNHLLQLLALVAMEPP-VSFDADSIRDEKVKVLKALRPIDPddNNTVRGQYGA--GEIGGV-SV 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 215 P-----DGF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERhwvpEQSRCLPQQII 287
Cdd:TIGR00871 297 PgyleeEGVdkDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN----ERDANPRNALV 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 288 FYIGHGElghpAILVSRNLFKPSLpTQKWKEVQ-DQPGLRLFGRPLSdyyayrpvreqDAYSTLLSHIFHCRKESFITTE 366
Cdd:TIGR00871 373 IRIQPDE----GVYLKFNAKKPGL-NFETRPVKlDFSYASRFGELLP-----------EAYERLLLDALLGDHTLFARDD 436
|
250 260 270
....*....|....*....|....*....|
gi 568930405 367 NLLASWVFWTPLLDSLAF---EVPRPYPGG 393
Cdd:TIGR00871 437 EVEEAWRIVTPILEAWAAnkgPSPPNYPAG 466
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
137-263 |
1.59e-25 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 110.55 E-value: 1.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSaAVLQHKLWAFQALRGLQKS----SAILGQYQAysGQVRREL 212
Cdd:COG0364 228 GRGGYYDGAGALRDMVQNHLLQLLCLVAMEPPASLDAD-AIRDEKVKVLRALRPITPEdvaeNTVRGQYTA--GWIGGEP 304
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568930405 213 QKP----DGF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKN 263
Cdd:COG0364 305 VPGyreePGVapDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKP 361
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
445-680 |
3.82e-91 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 283.11 E-value: 3.82e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 445 ITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGhySFPWAHTHLWLVDERCVPLSDPDSNFQG 524
Cdd:TIGR01198 1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ--PLDWSRIHLFLGDERYVPLDHADSNTGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 525 LQAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVAN---SSFDLVLLGMGTDGHTASLFPQSPTGLDG 601
Cdd:TIGR01198 79 AREALLDRVAIPASNIHPMPTEL-----SDIEEAAELYEQELAAAFQPivfPVFDLLLLGMGPDGHTASLFPHTPALQET 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 602 DQLV-VLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPlSGQLVWYMDYEAFLG 680
Cdd:TIGR01198 154 ERLVtVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLH-SGKTLWLLDYAAARK 232
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
447-671 |
3.76e-83 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 261.79 E-value: 3.76e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 447 AWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQ 526
Cdd:pfam01182 1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLDWSRVHVFWGDERCVPPDDPDSNYGMAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 527 AHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVANSS---FDLVLLGMGTDGHTASLFPQSPTGLDGDQ 603
Cdd:pfam01182 81 EALLSHVPIPASNVHPIPASA-----ADPEEAAAAYEAELRELLPDLElpvFDLVLLGMGPDGHTASLFPGSPALEETDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 604 LVV-LTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV-GHEPKKWPISGVVPLSGQLVW 671
Cdd:pfam01182 156 LVVaVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA---LRRAlAGDPDPLPAALVRPGAGETVW 222
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
450-673 |
1.36e-78 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 249.79 E-value: 1.36e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 450 EELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGhYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHL 529
Cdd:cd01400 1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLAAA-PALDWSKVHVFLGDERCVPPDDPDSNYRLAREAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 530 LQHVRVPYYNIHPMPVHLHqrlcaeEDQGAQTYASEISALVANS-SFDLVLLGMGTDGHTASLFPQSP-TGLDGDQLVVL 607
Cdd:cd01400 80 LSHVAIPAANIHPIPTELG------PEDAAAAYEKELRALFGGVpPFDLVLLGMGPDGHTASLFPGHPaLLEETDRLVVA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568930405 608 TE-SPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSGQLVWYM 673
Cdd:cd01400 154 VTdSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEA---LKRAlaGPDPEELPAARVLPRPGEVLWFL 219
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
449-677 |
2.56e-56 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 191.91 E-value: 2.56e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 449 PEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYS--FPWAHTHLWLVDERC-VPLSDPDSNFQGL 525
Cdd:COG0363 10 AEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEggLDWSRVHVFNLDEYVgLPPDHPQSNRRFM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 526 QAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLV 605
Cdd:COG0363 90 REALLDHVDIPPENIHIPDGEA-----EDPEAAAARYEALIAEA---GGIDLQLLGIGEDGHIAFNFPGSPFLSETDRVV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 606 VLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSgQLVW 671
Cdd:COG0363 162 TLDESTRQanarffgsipkvPPQAITLGIPTIMKAREILLLATGENKAEA---VAAAleGPVTEEVPASILQGHP-NVTW 237
|
....*.
gi 568930405 672 YMDYEA 677
Cdd:COG0363 238 FLDEAA 243
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
137-393 |
1.07e-50 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 178.02 E-value: 1.07e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSS----AILGQYQAysGQVRREL 212
Cdd:pfam02781 34 GRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAED-IRDEKVKVLRSLRPITPEDvednVVRGQYGA--GWIGGEP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 213 QK---------PDgfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwVP-----EQ 278
Cdd:pfam02781 111 VPgyreeegvpPD---SRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQFKD-----------VPhnlfrDP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 279 SRCLPQQIIFYIGHGElghpAILVSRNLFKpslptqkwkevqdqPGLRLFGRPLS---DYYAYRPVREQDAYSTLLSHIF 355
Cdd:pfam02781 177 GTLPPNELVIRIQPDE----GIYLKFNAKV--------------PGLGMRLRPVEldfSYSDRFGERIPEAYERLLLDVM 238
|
250 260 270
....*....|....*....|....*....|....*...
gi 568930405 356 HCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGG 393
Cdd:pfam02781 239 RGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPPYPAG 276
|
|
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
137-393 |
6.15e-35 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 139.89 E-value: 6.15e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAILGQYQAYS-GQVRRELQK- 214
Cdd:PTZ00309 275 GRGGYFDSYGIIRDVMQNHLLQILALLAMEKPVSLSAED-IRDEKVKVLKCIEPIKMEECVLGQYTASAdGSIPGYLEDe 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 215 --PDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwVPEqsrclpqqIIFYigh 292
Cdd:PTZ00309 354 gvPKD--STTPTFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKG-----------VDE--------FRPS--- 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 293 GELGHPAILVSRnlFKPSlPTQKWKEVQDQPGLrlfGRPLS------DYYAYRPVREQDAYSTLLSHIFHCRKESFITTE 366
Cdd:PTZ00309 410 GDDTQRNELVIR--AQPS-EAMYLKITAKVPGL---SNDLHqteldlTYKTRYNVRLPDAYERLILDALLGDSTNFVRKD 483
|
250 260
....*....|....*....|....*....
gi 568930405 367 NLLASWVFWTPLLDSL-AFEV-PRPYPGG 393
Cdd:PTZ00309 484 ELDVAWRIFTPLLHQIdRGEVkPEPYPFG 512
|
|
| PLN02539 |
PLN02539 |
glucose-6-phosphate 1-dehydrogenase |
137-394 |
4.03e-31 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 178154 [Multi-domain] Cd Length: 491 Bit Score: 127.53 E-value: 4.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAILGQYQAYsgqvRRELQKPD 216
Cdd:PLN02539 239 GRGGYFDEYGIIRDIIQNHLLQVLCLVAMEKPVSLKPEH-IRDEKVKVLQSVEPIKDEEVVLGQYEGY----RDDPTVPD 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 217 GfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwVP-EQSRCLPQqiifyighgel 295
Cdd:PLN02539 314 D--SNTPTFASVVLRINNERWEGVPFILKAGKALDSRKAEIRVQFKD-----------VPgDIFKCQKQ----------- 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 296 ghpailvSRNLF----KPSlPTQKWKEVQDQPGL--RLFGRPLSDYYA--YRPVREQDAYSTLLSHIFHCRKESFITTEN 367
Cdd:PLN02539 370 -------GRNEFvirlQPS-EAMYMKLTVKQPGLemSTVQSELDLSYGqrYQDVVIPEAYERLILDTIRGDQQHFVRRDE 441
|
250 260
....*....|....*....|....*....
gi 568930405 368 LLASWVFWTPLLDSL-AFEV-PRPYPGGA 394
Cdd:PLN02539 442 LKAAWEIFTPLLHRIdAGKVkPIPYKQGS 470
|
|
| PLN02360 |
PLN02360 |
probable 6-phosphogluconolactonase |
450-677 |
1.23e-30 |
|
probable 6-phosphogluconolactonase
Pssm-ID: 166001 [Multi-domain] Cd Length: 268 Bit Score: 121.12 E-value: 1.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 450 EELISKLASDIEAAAVQAVRHFGKFHLALSGGSSpIALFQQLATGHY--SFPWAHTHLWLVDERCVPLSDPDSNFQGLQA 527
Cdd:PLN02360 20 DELSTDLAEYIAELSEASVKERGVFAIALSGGSL-ISFMGKLCEAPYnkTVDWAKWYIFWADERVVAKNHADSNYKLAKD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 528 HLLQHVRVPYYNIHPmpvhLHQRLCAEEdqGAQTYASEISALVANSS-----------FDLVLLGMGTDGHTASLFPQSP 596
Cdd:PLN02360 99 GLLSKVPVVPSHVYS----INDTVTAEE--AATDYEFAIRQLVKTRTigvsdisdcpkFDLILLGMGSDGHVASLFPNHP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 597 T-GLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTL-VSRVGHEP--KKWPISGVVPLSGQLVWY 672
Cdd:PLN02360 173 AlEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLaIDDVTEGPdaPSLPARMVQPTKGKLVWF 252
|
....*
gi 568930405 673 MDYEA 677
Cdd:PLN02360 253 LDKPA 257
|
|
| PLN02333 |
PLN02333 |
glucose-6-phosphate 1-dehydrogenase |
137-394 |
1.27e-30 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215191 [Multi-domain] Cd Length: 604 Bit Score: 127.40 E-value: 1.27e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAILGQYQAYS-GQVR-----R 210
Cdd:PLN02333 335 GRGGYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAED-IRNEKVKVLRSMRPIQLEDVVIGQYKSHTkGGVTypaytD 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 211 ELQKPDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFK-------NRAYCTQSERHWVPEQSRCLP 283
Cdd:PLN02333 414 DKTVPKG--SLTPTFAAAALFIDNARWDGVPFLMKAGKALHTKSAEIRVQFRhvpgnlyNRNFGTDLDQATNELVIRVQP 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 284 QQiifyighgelghpAILVSRNLFKPSLptqkwkevqdqpGLRLFGRPLSDYYAYRPVRE-QDAYSTLLSHIFHCRKESF 362
Cdd:PLN02333 492 DE-------------AIYLKINNKVPGL------------GMRLDRSNLNLLYAARYSKEiPDAYERLLLDAIEGERRLF 546
|
250 260 270
....*....|....*....|....*....|....
gi 568930405 363 ITTENLLASWVFWTPLLDSLAFE--VPRPYPGGA 394
Cdd:PLN02333 547 IRSDELDAAWALFTPLLKELEEKkiIPEYYPYGS 580
|
|
| PLN02640 |
PLN02640 |
glucose-6-phosphate 1-dehydrogenase |
137-394 |
1.03e-29 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215344 [Multi-domain] Cd Length: 573 Bit Score: 124.36 E-value: 1.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAILGQYQAYSGQVRR------ 210
Cdd:PLN02640 306 GRGGYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAED-IRNEKVKVLRSMKPLQLEDVIVGQYKGHSKGGKSypaytd 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 211 ELQKPDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKN-------RAYCTQSERHWVPEQSRCLP 283
Cdd:PLN02640 385 DPTVPKH--SLTPTFAAAALFINNARWDGVPFLMKAGKALHTRRAEIRVQFRHvpgnlykRNFGTDLDKATNELVLRVQP 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 284 QQiifyighgelghpAILVSRNLFKPSLptqkwkevqdqpGLRLFGRPLSDYYAYRPVRE-QDAYSTLLSHIFHCRKESF 362
Cdd:PLN02640 463 DE-------------AIYLKINNKVPGL------------GMRLDRSDLNLLYRARYPREiPDAYERLLLDAIEGERRLF 517
|
250 260 270
....*....|....*....|....*....|....
gi 568930405 363 ITTENLLASWVFWTPLLDSLAFE--VPRPYPGGA 394
Cdd:PLN02640 518 IRSDELDAAWALFTPLLKELEEKkiIPELYPYGS 551
|
|
| PRK05722 |
PRK05722 |
glucose-6-phosphate 1-dehydrogenase; Validated |
137-393 |
2.92e-29 |
|
glucose-6-phosphate 1-dehydrogenase; Validated
Pssm-ID: 235579 [Multi-domain] Cd Length: 495 Bit Score: 122.16 E-value: 2.92e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNIsSSAAVLQHKLWAFQALRGLQ----KSSAILGQYQA--YSGQVRR 210
Cdd:PRK05722 229 GRGGYYDKSGALRDMVQNHLLQLLALVAMEPPASL-DADSIRDEKVKVLRALRPITpedvKENTVRGQYTAgwIGGKPVP 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 211 ELQKPDGF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKnrayctqserhwvpeqsrCLPQQiIF 288
Cdd:PRK05722 308 GYREEEGVnpDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFK------------------PPPHN-LF 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 289 YIGHGELgHPAILVSRnlfkpslptqkwkeVQD-----------QPGLRLFGRPLS---DYYAYRPVREQDAYSTLL--- 351
Cdd:PRK05722 369 EESAEEL-GPNKLVIR--------------IQPdegislrfnakVPGEGMELRPVKldfSYSEAFGEASPEAYERLLldv 433
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 568930405 352 ----SHIFHCRKEsfittenLLASWVFWTPLLDslAFEV----PRPYPGG 393
Cdd:PRK05722 434 mlgdQTLFVRRDE-------VEAAWKWVDPILE--AWEAdggpPPPYPAG 474
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
137-393 |
3.94e-28 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 118.58 E-value: 3.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPlNISSSAAVLQHKLWAFQALRGLQK--SSAILGQYQAysGQVRRElQK 214
Cdd:TIGR00871 221 GRGGYYDKSGALRDMVQNHLLQLLALVAMEPP-VSFDADSIRDEKVKVLKALRPIDPddNNTVRGQYGA--GEIGGV-SV 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 215 P-----DGF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERhwvpEQSRCLPQQII 287
Cdd:TIGR00871 297 PgyleeEGVdkDSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDVPSLLFKAN----ERDANPRNALV 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 288 FYIGHGElghpAILVSRNLFKPSLpTQKWKEVQ-DQPGLRLFGRPLSdyyayrpvreqDAYSTLLSHIFHCRKESFITTE 366
Cdd:TIGR00871 373 IRIQPDE----GVYLKFNAKKPGL-NFETRPVKlDFSYASRFGELLP-----------EAYERLLLDALLGDHTLFARDD 436
|
250 260 270
....*....|....*....|....*....|
gi 568930405 367 NLLASWVFWTPLLDSLAF---EVPRPYPGG 393
Cdd:TIGR00871 437 EVEEAWRIVTPILEAWAAnkgPSPPNYPAG 466
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
137-263 |
1.59e-25 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 110.55 E-value: 1.59e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSaAVLQHKLWAFQALRGLQKS----SAILGQYQAysGQVRREL 212
Cdd:COG0364 228 GRGGYYDGAGALRDMVQNHLLQLLCLVAMEPPASLDAD-AIRDEKVKVLRALRPITPEdvaeNTVRGQYTA--GWIGGEP 304
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568930405 213 QKP----DGF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKN 263
Cdd:COG0364 305 VPGyreePGVapDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKP 361
|
|
| PRK12853 |
PRK12853 |
glucose-6-phosphate dehydrogenase; |
137-393 |
1.94e-24 |
|
glucose-6-phosphate dehydrogenase;
Pssm-ID: 237233 [Multi-domain] Cd Length: 482 Bit Score: 107.29 E-value: 1.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 137 GRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAaVLQHKLWAFQALRGLQKSSAIL--GQYQAysGQVRRE--- 211
Cdd:PRK12853 219 GRGGFYDATGALRDMVQNHLLQLLALVAMEPPASFDADA-VRDEKAKVLRAIRPLDPDDVHTvrGQYTA--GTVGGEpvp 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 212 --LQKPDGF-QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKnRAYCTQserhwVPEQSRCLPQQIIF 288
Cdd:PRK12853 296 gyREEPGVDpDSRTETFVALKLEIDNWRWAGVPFYLRTGKRLAERRTEIVITFK-PVPHAL-----FRGTGVEPPNRLVI 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 289 YIGHGELGHPAILVSRnlfkpslptqkwkevqdqPGLRLFGRPLSDYYAYR-PVREQDAYSTLLSHIFHCRKESFITTEN 367
Cdd:PRK12853 370 RLQPDEGISLELNVKR------------------PGPGMRLRPVELDADYAdDERPLEAYERLLLDVLRGDPTLFVRADE 431
|
250 260
....*....|....*....|....*...
gi 568930405 368 LLASWVFWTPLLDSLA--FEVPRPYPGG 393
Cdd:PRK12853 432 VEAAWRIVDPVLDAWAadPVPPHEYPAG 459
|
|
| PRK12854 |
PRK12854 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
135-403 |
1.20e-22 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 237234 [Multi-domain] Cd Length: 484 Bit Score: 101.65 E-value: 1.20e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 135 LTGRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSsAAVLQHKLWAFQALRGLQKSSAILGQYQAYsgqvRRELQK 214
Cdd:PRK12854 225 VDTRAAFYDATGAYRDMVVTHLFQVLAFVAMEPPTALEP-DAISEEKNKVFRSMRPLDPAEVVRGQYSGY----RDEPGV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 215 PDgfQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNrayctqserhwvpeqsrclPQQIIFYIGHGE 294
Cdd:PRK12854 300 AP--DSTTETFVALKVWIDNWRWAGVPFYLRTGKRMAEGQRIISIAFRE-------------------PPYSMFPAGSVG 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 295 LGHPAILVsrnlFKPSLPTQKWKEVQDQ---PGLRLfgRPLSDYYAYRPVREQ----DAYSTLLSHIFHCRKESFITTEN 367
Cdd:PRK12854 359 AQGPDHLT----FDLADNSKVSLSFYGKrpgPGMRL--DKLSLQFSLKDTGPKgdvlEAYERLILDALRGDHTLFTTADG 432
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 568930405 368 LLASWVFWTPLLDSLAfeVPRPYPGG-----------AENGQLLDFE 403
Cdd:PRK12854 433 IESLWEVSQPLLEDPP--PVKPYAPGswgpnaihqlaAPDAWRLPFE 477
|
|
| GlcN6P_deaminase |
cd01399 |
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ... |
461-660 |
4.89e-15 |
|
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.
Pssm-ID: 238693 [Multi-domain] Cd Length: 232 Bit Score: 74.83 E-value: 4.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 461 EAAA---VQAVRHFGKFHLALSGGSSPIALFQQLATGHYS--FPWAHTHLWLVDERcVPLS--DPDSNFQGLQAHLLQHV 533
Cdd:cd01399 5 EAAAeliAELIREKPPAVLGLATGSTPLGVYEELIELHKEggLSFSNVTTFNLDEY-VGLPpdHPQSYHYFMRENLFDHI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 534 RVPYYNIHPMPVhlhqrLCAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTAslFPQSPTGLDGD-QLVVLTES-- 610
Cdd:cd01399 84 DIKPENIHIPDG-----NAADLEAECRRYEALIAEA---GGIDLQLLGIGENGHIG--FNEPGSSLDSRtRVVTLDEStr 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568930405 611 -----PFR-----PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRVGHEP--KKWPIS 660
Cdd:cd01399 154 qanarFFDgdedvPTQAITMGIGTIMKAKEILLLATGEGKAEA---VKKALEGPvtEECPAS 212
|
|
| SugarP_isomerase |
cd00458 |
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate ... |
473-588 |
6.60e-09 |
|
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium, the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate. 6PGL converts 6-phosphoglucono-1,5-lactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway.
Pssm-ID: 238258 Cd Length: 169 Bit Score: 55.82 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 473 KFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLhqrlc 552
Cdd:cd00458 21 DMVIGLGTGSTPAYFYKLLGEKLKRGEISDIVGFPTDERYVPLDSDQSNFRQAKLLAFEHDIIPASNVHYVDTSL----- 95
|
90 100 110
....*....|....*....|....*....|....*.
gi 568930405 553 AEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHT 588
Cdd:cd00458 96 PIEKACEKYEREILDQV---DAIDLAVDGAGYRAGT 128
|
|
| PTZ00285 |
PTZ00285 |
glucosamine-6-phosphate isomerase; Provisional |
474-660 |
3.08e-07 |
|
glucosamine-6-phosphate isomerase; Provisional
Pssm-ID: 140308 Cd Length: 253 Bit Score: 52.07 E-value: 3.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 474 FHLALSGGSSPIALFQQLATGH----YSFpwAHTHLWLVDERC-VPLSDPDSNFQGLQAHLLQHVrvpyyNIHPMPVHLH 548
Cdd:PTZ00285 35 FVLGLPTGSTPLPTYQELIRAYregrVSF--SNVVTFNMDEYVgLPRDHPQSYHYFMKENFFDHV-----DIKEENRHIL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 549 QRLCAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPtgLDGDQLVV-LTESPFR-------------P 614
Cdd:PTZ00285 108 NGTAPDLEEECRRYEEKIRAV---GGIDLFLAGIGTDGHIAFNEPGSS--LDSRTRVKsLNQETIDanarffgndiskvP 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568930405 615 HQRMSLSLPLINRAKKVAVLVMGRTKREITT--LVSRVGHepkKWPIS 660
Cdd:PTZ00285 183 TMALTVGIRTIMEAREVLLLATGASKAIAVArcVEGGVTH---MCPAS 227
|
|
| nagB |
PRK00443 |
glucosamine-6-phosphate deaminase; Provisional |
453-660 |
7.07e-06 |
|
glucosamine-6-phosphate deaminase; Provisional
Pssm-ID: 179028 [Multi-domain] Cd Length: 261 Bit Score: 47.90 E-value: 7.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 453 ISKLASDIEAAAVQA--VRHFGKFHLALSGGSSPIALFQQLATGHYS--FPWAHTHLWLVDE-RCVPLSDPDS--NFqgL 525
Cdd:PRK00443 12 VGKWAARHIANRINAflPTKERPFVLGLATGSSPLETYKALIELHKAgkVDFSRVTTFNLDEyVGLPADHPESyrYF--M 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 526 QAHLLQHVrvpyyNIHPMPVHLHQRLCAEEDQGAQTYASEIsalVANSSFDLVLLGMGTDGHTAslFPQSPTGLDGDQLV 605
Cdd:PRK00443 90 RENFFDHV-----DIPPENINLLNGNAPDPEAECRRYEEKI---KSAGGIDLQILGIGENGHIA--FNEPGSSFASRTRI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568930405 606 V-LTESPFR-------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIT--TLVSRVGHEpkkWPIS 660
Cdd:PRK00443 160 KtLTEDTRIansrffdgdieqvPKYALTVGVGTILDAKEIMLLAPGHNKAEAVkaAVEGPVNHM---WPAS 227
|
|
| PRK02122 |
PRK02122 |
glucosamine-6-phosphate deaminase-like protein; Validated |
449-643 |
2.23e-05 |
|
glucosamine-6-phosphate deaminase-like protein; Validated
Pssm-ID: 235005 [Multi-domain] Cd Length: 652 Bit Score: 47.72 E-value: 2.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 449 PEELISKLASDIeAAAVQAVRHFGKFH-LALSGGSSPIALFQQLATGH----YSFPwaHTHLWLVDERcVPLS--DPDSN 521
Cdd:PRK02122 36 SEEASRAVAQEI-ATLIRERQAEGKPCvLGLATGSSPIGVYAELIRMHreegLSFK--NVITFNLDEY-YPMQpdSLQSY 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 522 FQGLQAHLLQHVRVPYYNIHPMPVHLHQrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTAslFPQSPTGLD- 600
Cdd:PRK02122 112 HRFMKENLFDHVDIPPENIHIPDGTIPK---EEIDEYCRDYEEKIEAA---GGIDFQLLGIGRTGHIG--FNEPGSGRNs 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568930405 601 GDQLVVLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREI 643
Cdd:PRK02122 184 RTRLVTLDHITRRdaasdffgeenvPRKAITMGVGTILKARRIVLLAWGEHKAPI 238
|
|
| PRK12358 |
PRK12358 |
glucosamine-6-phosphate deaminase; |
473-587 |
1.07e-03 |
|
glucosamine-6-phosphate deaminase;
Pssm-ID: 183470 Cd Length: 239 Bit Score: 41.28 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930405 473 KFHLALSGGSSPIALFQQLATGHYSFPW-AHTHLWLVDErcVPLSDPDS---NFQGLQAHLLQHVRVPYYNIHPMPVhlh 548
Cdd:PRK12358 29 RVNLAITAGSTPKGMYEYLITLVKGKAWyDNVHYYNFDE--IPFRGKEGegvTITNLRNLFFTPAGIKEENIHKLTI--- 103
|
90 100 110
....*....|....*....|....*....|....*....
gi 568930405 549 qrlcaeedqgaQTYASEISALVANSSFDLVLLGMGTDGH 587
Cdd:PRK12358 104 -----------DNYREHDQKLARDGGLDLVVLGLGADGH 131
|
|
| |
