|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
365-584 |
7.09e-125 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
:
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 369.20 E-value: 7.09e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 365 LKSSHVRDAVAVIQYLVWLEKNVPKG-TVDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSS 443
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 444 DEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRALWEVGLNYGHGTG 523
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 569009170 524 HGIGNFLCVHEWPVG--FQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEAKTKYPGD 584
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
195-361 |
1.24e-62 |
|
Creatinase/Prolidase N-terminal domain;
:
Pssm-ID: 465053 Cd Length: 159 Bit Score: 205.03 E-value: 1.24e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 195 ERPPVPSQPIYALPKEFTGSTWQEKVSAVRSYM-EHHAktpTGVLLSALDETAWLFNLRSSDIPYNPFFYSYALLTNSSI 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALkEKGA---DALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 274 RLFVNKSRFSLETLQYLNTNctlpmCVQLEDYSQVRDSVKAYASgDVKILIGVSYTTYGVYEVIPKEKLVTDTYSPVMLI 353
Cdd:pfam16189 78 TLFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAALAA-GKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLM 151
|
....*...
gi 569009170 354 KAVKNSKE 361
Cdd:pfam16189 152 KAVKNETE 159
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
585-648 |
5.11e-21 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
:
Pssm-ID: 465052 Cd Length: 63 Bit Score: 86.69 E-value: 5.11e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569009170 585 YLTFELVSFVPYDRNLIDVRLLSPEQLQYLNRYYQTIRENVGPELQRRQllEEFAWLEQHTEPL 648
Cdd:pfam16188 2 FLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEE--DALEWLKRATRPI 63
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
53-177 |
1.09e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
:
Pssm-ID: 460159 Cd Length: 128 Bit Score: 68.10 E-value: 1.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 53 RLAALRQQMETWNLSAYIIPDtdahmseyigkpDKRREWISGFTGSAGTA-VVTMGKAAVWTD-SRYWTQAeRQMDCNWE 130
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTS------------PENLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 569009170 131 LHKEVSISSIVAWILAEVPDGQNVGFDPFLFSVDSWKNYDQGFQDSS 177
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALPGAE 114
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
365-584 |
7.09e-125 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 369.20 E-value: 7.09e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 365 LKSSHVRDAVAVIQYLVWLEKNVPKG-TVDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSS 443
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 444 DEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRALWEVGLNYGHGTG 523
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 569009170 524 HGIGNFLCVHEWPVG--FQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEAKTKYPGD 584
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
195-361 |
1.24e-62 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 205.03 E-value: 1.24e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 195 ERPPVPSQPIYALPKEFTGSTWQEKVSAVRSYM-EHHAktpTGVLLSALDETAWLFNLRSSDIPYNPFFYSYALLTNSSI 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALkEKGA---DALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 274 RLFVNKSRFSLETLQYLNTNctlpmCVQLEDYSQVRDSVKAYASgDVKILIGVSYTTYGVYEVIPKEKLVTDTYSPVMLI 353
Cdd:pfam16189 78 TLFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAALAA-GKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLM 151
|
....*...
gi 569009170 354 KAVKNSKE 361
Cdd:pfam16189 152 KAVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
340-582 |
1.71e-58 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 199.28 E-value: 1.71e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 340 EKLVTDTYSPVMLIKAVKNSKEQALLKSSHVRDAVAVIQYLVWLEKNVPKGTVDefsgAEYIDELRRNEnfSSGPSFETI 419
Cdd:COG0006 57 ERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRPGVTEREVA----AELEAAMRRRG--AEGPSFDTI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 420 SASGLNAALAHYSPTkelHRKLSSDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVfPAATS 499
Cdd:COG0006 131 VASGENAAIPHYTPT---DRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAAL-KPGVT 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 500 GRVIEAFARRALWEVGL--NYGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEA 577
Cdd:COG0006 207 GGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQISPGNDRPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED 284
|
....*....
gi 569009170 578 K----TKYP 582
Cdd:COG0006 285 GaevlTRLP 293
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
363-576 |
3.11e-49 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 171.27 E-value: 3.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 363 ALLKSSHVRDAVAVIQYLVWLEKNVpkgtvDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKelhRKLS 442
Cdd:pfam00557 1 ELMRKAARIAAAALEAALAAIRPGV-----TERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYIPND---RVLK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 443 SDEMYLVDSGGQYWDG-TTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAfARRALWEVGL--NYG 519
Cdd:pfam00557 73 PGDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAA-AREVLEEAGLgeYFP 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 569009170 520 HGTGHGIGnfLCVHEWP-VGFQYNNIAMAKGMFTSIEPGYYH-DGEFGIRLEDVALVVE 576
Cdd:pfam00557 152 HGLGHGIG--LEVHEGPyISRGGDDRVLEPGMVFTIEPGIYFiPGWGGVRIEDTVLVTE 208
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
585-648 |
5.11e-21 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 86.69 E-value: 5.11e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569009170 585 YLTFELVSFVPYDRNLIDVRLLSPEQLQYLNRYYQTIRENVGPELQRRQllEEFAWLEQHTEPL 648
Cdd:pfam16188 2 FLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEE--DALEWLKRATRPI 63
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
415-576 |
3.03e-16 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 80.75 E-value: 3.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 415 SFETISASGLNAALAHyspTKELHRKLSSDEMYLVDSGGQYWDGTTDITRTVhW----GTPTAFQK--EAYTRVLMGNID 488
Cdd:PRK09795 180 SFDTIVASGWRGALPH---GKASDKIVAAGEFVTLDFGALYQGYCSDMTRTL-LvngeGVSAESHPlfNVYQIVLQAQLA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 489 LSRLVFPAATSGRVIEAfARRALWEVGLN--YGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGI 566
Cdd:PRK09795 256 AISAIRPGVRCQQVDDA-ARRVITEAGYGdyFGHNTGHAIG--IEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGV 332
|
170
....*....|
gi 569009170 567 RLEDVALVVE 576
Cdd:PRK09795 333 RIEDVVLVTP 342
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
53-177 |
1.09e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 68.10 E-value: 1.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 53 RLAALRQQMETWNLSAYIIPDtdahmseyigkpDKRREWISGFTGSAGTA-VVTMGKAAVWTD-SRYWTQAeRQMDCNWE 130
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTS------------PENLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 569009170 131 LHKEVSISSIVAWILAEVPDGQNVGFDPFLFSVDSWKNYDQGFQDSS 177
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALPGAE 114
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
365-584 |
7.09e-125 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 369.20 E-value: 7.09e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 365 LKSSHVRDAVAVIQYLVWLEKNVPKG-TVDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKELHRKLSS 443
Cdd:cd01085 2 MRAAHIRDGVALVEFLAWLEQEVPKGeTITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKISP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 444 DEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRALWEVGLNYGHGTG 523
Cdd:cd01085 82 DGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGTG 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 569009170 524 HGIGNFLCVHEWPVG--FQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEAKTKYPGD 584
Cdd:cd01085 162 HGVGSFLNVHEGPQSisPAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVEAETTEFGG 224
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
195-361 |
1.24e-62 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 205.03 E-value: 1.24e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 195 ERPPVPSQPIYALPKEFTGSTWQEKVSAVRSYM-EHHAktpTGVLLSALDETAWLFNLRSSDIPYNPFFYSYALLTNSSI 273
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALkEKGA---DALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDDEA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 274 RLFVNKSRFSLETLQYLNTNctlpmCVQLEDYSQVRDSVKAYASgDVKILIGVSYTTYGVYEVIPKEKLVTDTYSPVMLI 353
Cdd:pfam16189 78 TLFVDPEKLSDEVRAHLEEN-----GVEIRPYDDIYEDLAALAA-GKKVLLDPSRTSYALYSALPAGAKVVEAPSPITLM 151
|
....*...
gi 569009170 354 KAVKNSKE 361
Cdd:pfam16189 152 KAVKNETE 159
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
340-582 |
1.71e-58 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 199.28 E-value: 1.71e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 340 EKLVTDTYSPVMLIKAVKNSKEQALLKSSHVRDAVAVIQYLVWLEKNVPKGTVDefsgAEYIDELRRNEnfSSGPSFETI 419
Cdd:COG0006 57 ERELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRPGVTEREVA----AELEAAMRRRG--AEGPSFDTI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 420 SASGLNAALAHYSPTkelHRKLSSDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVfPAATS 499
Cdd:COG0006 131 VASGENAAIPHYTPT---DRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDEQREIYEAVLEAQEAAIAAL-KPGVT 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 500 GRVIEAFARRALWEVGL--NYGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVEA 577
Cdd:COG0006 207 GGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQISPGNDRPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED 284
|
....*....
gi 569009170 578 K----TKYP 582
Cdd:COG0006 285 GaevlTRLP 293
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
363-576 |
3.11e-49 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 171.27 E-value: 3.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 363 ALLKSSHVRDAVAVIQYLVWLEKNVpkgtvDEFSGAEYIDELRRNENFSSGPSFETISASGLNAALAHYSPTKelhRKLS 442
Cdd:pfam00557 1 ELMRKAARIAAAALEAALAAIRPGV-----TERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYIPND---RVLK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 443 SDEMYLVDSGGQYWDG-TTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAfARRALWEVGL--NYG 519
Cdd:pfam00557 73 PGDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAA-AREVLEEAGLgeYFP 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 569009170 520 HGTGHGIGnfLCVHEWP-VGFQYNNIAMAKGMFTSIEPGYYH-DGEFGIRLEDVALVVE 576
Cdd:pfam00557 152 HGLGHGIG--LEVHEGPyISRGGDDRVLEPGMVFTIEPGIYFiPGWGGVRIEDTVLVTE 208
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
412-576 |
6.41e-36 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 134.17 E-value: 6.41e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 412 SGPSFETISASGLNAALAHYSPTKelhRKLSSDEMYLVDSGGqYWDG-TTDITRTVHWGTPTAFQKEAYTRVLMGN---I 487
Cdd:cd01092 45 EGPSFDTIVASGPNSALPHGVPSD---RKIEEGDLVLIDFGA-IYDGyCSDITRTVAVGEPSDELKEIYEIVLEAQqaaI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 488 DLSRlvfPAATsGRVIEAFARRALWEVGL--NYGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFG 565
Cdd:cd01092 121 KAVK---PGVT-AKEVDKAARDVIEEAGYgeYFIHRTGHGVG--LEVHEAPYISPGSDDVLEEGMVFTIEPGIYIPGKGG 194
|
170
....*....|.
gi 569009170 566 IRLEDVALVVE 576
Cdd:cd01092 195 VRIEDDVLVTE 205
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
412-579 |
2.73e-29 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 115.63 E-value: 2.73e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 412 SGPSFETISASGLNAALAHYSPTkelHRKLSSDEMYLVDSGGQYWDGTTDITRTVHWGTPTAFQKEAYTRVLMGNIDLSR 491
Cdd:cd01066 44 GYPAGPTIVGSGARTALPHYRPD---DRRLQEGDLVLVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALA 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 492 LVFPAATsGRVIEAFARRAL--WEVGLNYGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGIRLE 569
Cdd:cd01066 121 ALRPGVT-AEEVDAAAREVLeeHGLGPNFGHRTGHGIG--LEIHEPPVLKAGDDTVLEPGMVFAVEPGLYLPGGGGVRIE 197
|
170
....*....|
gi 569009170 570 DVALVVEAKT 579
Cdd:cd01066 198 DTVLVTEDGP 207
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|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
585-648 |
5.11e-21 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 86.69 E-value: 5.11e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569009170 585 YLTFELVSFVPYDRNLIDVRLLSPEQLQYLNRYYQTIRENVGPELQRRQllEEFAWLEQHTEPL 648
Cdd:pfam16188 2 FLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLEEEE--DALEWLKRATRPI 63
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|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
398-576 |
2.17e-17 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 82.24 E-value: 2.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 398 AEYIDELRRNENfssGPSFETISASGLNAALAHYSptkELHRKLSSDEMYLVDSGGQYWDGTTDITRTvhW---GTPTAF 474
Cdd:cd01087 33 AEFEYEFRSRGA---RLAYSYIVAAGSNAAILHYV---HNDQPLKDGDLVLIDAGAEYGGYASDITRT--FpvnGKFTDE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 475 QKEAYTRVLMGNIDLSRLVFPAATSGRVIEAFARRA---LWEVGLNYG----------------HGTGHGIGnfLCVHEW 535
Cdd:cd01087 105 QRELYEAVLAAQKAAIAACKPGVSYEDIHLLAHRVLaegLKELGILKGdvdeivesgayakffpHGLGHYLG--LDVHDV 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 569009170 536 PVGFQYN--NIAMAKGMFTSIEPGYY---HDGEF-------GIRLEDVALVVE 576
Cdd:cd01087 183 GGYLRYLrrARPLEPGMVITIEPGIYfipDLLDVpeyfrggGIRIEDDVLVTE 235
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| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
415-576 |
3.03e-16 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 80.75 E-value: 3.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 415 SFETISASGLNAALAHyspTKELHRKLSSDEMYLVDSGGQYWDGTTDITRTVhW----GTPTAFQK--EAYTRVLMGNID 488
Cdd:PRK09795 180 SFDTIVASGWRGALPH---GKASDKIVAAGEFVTLDFGALYQGYCSDMTRTL-LvngeGVSAESHPlfNVYQIVLQAQLA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 489 LSRLVFPAATSGRVIEAfARRALWEVGLN--YGHGTGHGIGnfLCVHEWPVGFQYNNIAMAKGMFTSIEPGYYHDGEFGI 566
Cdd:PRK09795 256 AISAIRPGVRCQQVDDA-ARRVITEAGYGdyFGHNTGHAIG--IEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGV 332
|
170
....*....|
gi 569009170 567 RLEDVALVVE 576
Cdd:PRK09795 333 RIEDVVLVTP 342
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| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
53-177 |
1.09e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 68.10 E-value: 1.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 53 RLAALRQQMETWNLSAYIIPDtdahmseyigkpDKRREWISGFTGSAGTA-VVTMGKAAVWTD-SRYWTQAeRQMDCNWE 130
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTS------------PENLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAA-AESAPDFD 67
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90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 569009170 131 LHKEVSISSIVAWILAEVPDGQNVGFDPFLFSVDSWKNYDQGFQDSS 177
Cdd:pfam01321 68 VVPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALPGAE 114
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| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
414-577 |
6.91e-08 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 55.50 E-value: 6.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 414 PSFETISASGLNAALAHYSptkELHRKLSSDEMYLVDSGGQYWDGTTDITRT--VHwGTPTAFQKEAYTRVLMGNIDLSR 491
Cdd:PRK10879 225 PSYNTIVGSGENGCILHYT---ENESEMRDGDLVLIDAGCEYKGYAGDITRTfpVN-GKFTPAQREIYDIVLESLETSLR 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 492 LVFPAATSGRVIEAFAR---RALWEVGLNYG----------------HGTGHGIGnfLCVHEwpVGF--QYNNIAMAKGM 550
Cdd:PRK10879 301 LYRPGTSIREVTGEVVRimvSGLVKLGILKGdvdqliaenahrpffmHGLSHWLG--LDVHD--VGVygQDRSRILEPGM 376
|
170 180 190
....*....|....*....|....*....|....*.
gi 569009170 551 FTSIEPGYY--HDGE-------FGIRLEDVALVVEA 577
Cdd:PRK10879 377 VLTVEPGLYiaPDADvpeqyrgIGIRIEDDIVITET 412
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| PRK15173 |
PRK15173 |
peptidase; Provisional |
461-588 |
7.48e-06 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 48.56 E-value: 7.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 461 DITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAfARRALWEVGL-NYGHG-TGHGIGNFLCVHEWPVG 538
Cdd:PRK15173 190 DIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDS-TMEVIKKSGLpNYNRGhLGHGNGVFLGLEESPFV 268
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 569009170 539 FQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALV----VEAKTKYPGDYLTF 588
Cdd:PRK15173 269 STHATESFTSGMVLSLETPYYGYNLGSIMIEDMILInkegIEFLSKLPRDLVSF 322
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| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
461-588 |
1.18e-05 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 48.16 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 461 DITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAfARRALWEVGL-NYGHG-TGHGIGNFLCVHEWPVG 538
Cdd:PRK14575 273 DIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDS-TMEVIKKSGLpNYNRGhLGHGNGVFLGLEESPFV 351
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 569009170 539 FQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALV----VEAKTKYPGDYLTF 588
Cdd:PRK14575 352 STHATESFTSGMVLSLETPYYGYNLGSIMIEDMILInkegIEFLSKLPRDLVSF 405
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|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
461-576 |
2.36e-03 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 40.77 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009170 461 DITRTVHWGTPTAFQKEAYTRVLMGNIDLSRLVFPAATSGRVIEAfARRALWEVGL---NYGHgTGHGIGNFLCVHEWPV 537
Cdd:PRK14576 272 DLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKLKAVFDS-TMAVIKTSGLphyNRGH-LGHGDGVFLGLEEVPF 349
|
90 100 110
....*....|....*....|....*....|....*....
gi 569009170 538 GFQYNNIAMAKGMFTSIEPGYYHDGEFGIRLEDVALVVE 576
Cdd:PRK14576 350 VSTQATETFCPGMVLSLETPYYGIGVGSIMLEDMILITD 388
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| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
500-556 |
2.77e-03 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 40.21 E-value: 2.77e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 569009170 500 GRVIEAFARRALWEVGLNYghgTGHGIGNFLcvHEWPVGFQY-----NNIAMAKGMFTSIEP 556
Cdd:PRK12896 153 GRAIEDFAKKNGYSVVRDL---TGHGVGRSL--HEEPSVILTytdplPNRLLRPGMTLAVEP 209
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| HemE |
COG0407 |
Uroporphyrinogen-III decarboxylase HemE [Coenzyme transport and metabolism]; ... |
466-526 |
4.11e-03 |
|
Uroporphyrinogen-III decarboxylase HemE [Coenzyme transport and metabolism]; Uroporphyrinogen-III decarboxylase HemE is part of the Pathway/BioSystem: Heme biosynthesis
Pssm-ID: 440176 [Multi-domain] Cd Length: 336 Bit Score: 39.82 E-value: 4.11e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 569009170 466 VHWGTPTAFQKEAY--TRVLMGNIDLSRLVFPAatSGRVIEAFARRALWEVGLNYGH--GTGHGI 526
Cdd:COG0407 254 VDWRVDLAEAKERLgdKVALQGNLDPALLLLNG--TPEEVEAEVKRILDAGGGGPGHifNLGHGI 316
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