|
Name |
Accession |
Description |
Interval |
E-value |
| SM-ATX |
pfam14438 |
Ataxin 2 SM domain; This SM domain is found in Ataxin-2. |
123-196 |
1.62e-19 |
|
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
Pssm-ID: 464173 Cd Length: 78 Bit Score: 83.76 E-value: 1.62e-19
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 123 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVMLVHFR 196
Cdd:pfam14438 1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
|
|
| LsmAD |
pfam06741 |
LsmAD domain; This domain is found associated with Lsm domain. |
264-326 |
1.54e-17 |
|
LsmAD domain; This domain is found associated with Lsm domain.
Pssm-ID: 461998 [Multi-domain] Cd Length: 65 Bit Score: 77.61 E-value: 1.54e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 264 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 326
Cdd:pfam06741 1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
336-949 |
1.90e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 336 GRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 415
Cdd:PHA03247 2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 416 LRGAKtlsspSNRPSgetsvPPPPAAPPFLPVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSasipvtssvsdpgv 495
Cdd:PHA03247 2581 AVTSR-----ARRPD-----APPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN-------------- 2636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 496 gsiSPASPKISLAPTDVKELSTKEPGRTLEPQElARIAGKVPGLQNEQKRFQLEELRKfgaqfklqPSSSPENSLDPFPP 575
Cdd:PHA03247 2637 ---EPDPHPPPTVPPPERPRDDPAPGRVSRPRR-ARRLGRAAQASSPPQRPRRRAARP--------TVGSLTSLADPPPP 2704
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 576 rilkeepkgkekevdglltsepmgspvssktesvsdkEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLikgedkdeGP 655
Cdd:PHA03247 2705 -------------------------------------PPTPEPAPHALVSATPLPPGPAAARQASPALPA--------AP 2739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 656 VAEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQMY 735
Cdd:PHA03247 2740 APPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 736 PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMahyP 815
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG----------------PPPPSLPLGGSVAPGGDVRRRPP---S 2868
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 816 SQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPSAEQPTPQAlyatvhqsyPHHATQLHAHQPQPATTPTGSQPQSQ 893
Cdd:PHA03247 2869 RSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQA---------PPPPQPQPQPPPPPQPQPPPPPPPRP 2939
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 578828458 894 HAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 949
Cdd:PHA03247 2940 QPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
797-1035 |
2.74e-07 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 54.66 E-value: 2.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 797 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPSAEQPTPQALYAT 862
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 863 VHQSYPHHAT------QLHAHQPQPATTPTGS---QPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSL 933
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPApaqPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 934 PPGPSAQSPQSSFPQPAAVYAIHHQQLPhgfTNMAHVTQAhvqtgitaappphpGAPHPPQVMLLHPPQSHGGPPQGAVP 1013
Cdd:pfam09770 266 LQRPQSPQPDPAQPSIQPQAQQFHQQPP---PVPVQPTQI--------------LQNPNRLSAARVGYPQNPQPGVQPAP 328
|
250 260
....*....|....*....|..
gi 578828458 1014 QSGVPALSASTPSPYPYIGHPQ 1035
Cdd:pfam09770 329 AHQAHRQQGSFGRQAPIITHPQ 350
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
821-958 |
5.94e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 40.56 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 821 APMLQSNPRMLTSGSHPQaivssstPQYpsaEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPV 900
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQ-------PPY---YGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLRPNGLAPMNAVRAPSRN 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 901 QQHQAGQAPhlgsgqpqqnlyhpgaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 958
Cdd:TIGR01628 450 AQNAAQKPP--------------------MQPVMYPPNYQSLPLSQDLPQPQSTASQG 487
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SM-ATX |
pfam14438 |
Ataxin 2 SM domain; This SM domain is found in Ataxin-2. |
123-196 |
1.62e-19 |
|
Ataxin 2 SM domain; This SM domain is found in Ataxin-2.
Pssm-ID: 464173 Cd Length: 78 Bit Score: 83.76 E-value: 1.62e-19
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 123 MLHFLTAVVGSTCDVKVKNGTTYEGIFKTLS--SKFELAVDAVHRKASE--PAGGPRREDIVDTMVFKPSDVMLVHFR 196
Cdd:pfam14438 1 LLFLLTSLVGLVVEVTTKNGEVYEGIFSTASleKDFGVVLKMARRIKKSngSGLNPVRGEIVDTMIFPAKDIVDIEAK 78
|
|
| LsmAD |
pfam06741 |
LsmAD domain; This domain is found associated with Lsm domain. |
264-326 |
1.54e-17 |
|
LsmAD domain; This domain is found associated with Lsm domain.
Pssm-ID: 461998 [Multi-domain] Cd Length: 65 Bit Score: 77.61 E-value: 1.54e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 264 YGVKTTYDSSLssYTVPLEKdNSEEFRQRELRAAQLAREIESSPQYRLRIAMEN-----DDGRTEEEK 326
Cdd:pfam06741 1 FGVKSTYDENL--YTTKLDR-SSPDYKEREAEAERIAREIEGSASTNAHVAEERgldvdDSGLDEEDK 65
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
336-949 |
1.90e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 336 GRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPgpgsearginggPSRMSPKAQRP 415
Cdd:PHA03247 2513 SRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVP------------PPRPAPRPSEP 2580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 416 LRGAKtlsspSNRPSgetsvPPPPAAPPFLPVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSasipvtssvsdpgv 495
Cdd:PHA03247 2581 AVTSR-----ARRPD-----APPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN-------------- 2636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 496 gsiSPASPKISLAPTDVKELSTKEPGRTLEPQElARIAGKVPGLQNEQKRFQLEELRKfgaqfklqPSSSPENSLDPFPP 575
Cdd:PHA03247 2637 ---EPDPHPPPTVPPPERPRDDPAPGRVSRPRR-ARRLGRAAQASSPPQRPRRRAARP--------TVGSLTSLADPPPP 2704
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 576 rilkeepkgkekevdglltsepmgspvssktesvsdkEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLikgedkdeGP 655
Cdd:PHA03247 2705 -------------------------------------PPTPEPAPHALVSATPLPPGPAAARQASPALPA--------AP 2739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 656 VAEQVKKSTLNPNAKEFNPTKPLlsvnksTSTPTSPGPrthstPSIPVlTAGQSGLYSPQYISYIPQIHMGPAVQAPQMY 735
Cdd:PHA03247 2740 APPAVPAGPATPGGPARPARPPT------TAGPPAPAP-----PAAPA-AGPPRRLTRPAVASLSESRESLPSPWDPADP 2807
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 736 PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPmmqaaaaagpplvaatPYSSYIPYNPQQFPGQPAMMQPMahyP 815
Cdd:PHA03247 2808 PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG----------------PPPPSLPLGGSVAPGGDVRRRPP---S 2868
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 816 SQPVFAPMLQSNP--RMLTSGSHPQAIVSSSTPQYPSAEQPTPQAlyatvhqsyPHHATQLHAHQPQPATTPTGSQPQSQ 893
Cdd:PHA03247 2869 RSPAAKPAAPARPpvRRLARPAVSRSTESFALPPDQPERPPQPQA---------PPPPQPQPQPPPPPQPQPPPPPPPRP 2939
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 578828458 894 HAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQP 949
Cdd:PHA03247 2940 QPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPqPAPSREAPASSTPPL 2996
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
797-1035 |
2.74e-07 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 54.66 E-value: 2.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 797 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSG----SHPQAI----VSSS------TPQYPSAEQPTPQALYAT 862
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekyKEPEPIpdlqVDASlwgvapKKAAAPAPAPQPAAQPAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 863 VHQSYPHHAT------QLHAHQPQPATTPTGS---QPQSQHAAPSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSL 933
Cdd:pfam09770 186 LPAPSRKMMSleeveaAMRAQAKKPAQQPAPApaqPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 934 PPGPSAQSPQSSFPQPAAVYAIHHQQLPhgfTNMAHVTQAhvqtgitaappphpGAPHPPQVMLLHPPQSHGGPPQGAVP 1013
Cdd:pfam09770 266 LQRPQSPQPDPAQPSIQPQAQQFHQQPP---PVPVQPTQI--------------LQNPNRLSAARVGYPQNPQPGVQPAP 328
|
250 260
....*....|....*....|..
gi 578828458 1014 QSGVPALSASTPSPYPYIGHPQ 1035
Cdd:pfam09770 329 AHQAHRQQGSFGRQAPIITHPQ 350
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
815-946 |
2.41e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 52.01 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 815 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP-----QYPSAEQPT-PQALYATVHQSYPHHATQLHAHQPQpATTPTGS 888
Cdd:PRK10263 740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPvapqpQYQQPQQPVaPQPQYQQPQQPVAPQPQYQQPQQPV-APQPQYQ 818
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578828458 889 QPQSQHAAPSPVQQHQAGQAPhlgsgQPQQNLYHPGALTG----------TP-PS---LPPGPSAQSPQSSF 946
Cdd:PRK10263 819 QPQQPVAPQPQYQQPQQPVAP-----QPQDTLLHPLLMRNgdsrplhkptTPlPSldlLTPPPSEVEPVDTF 885
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
835-998 |
2.44e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 51.58 E-value: 2.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 835 SHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPHLg 912
Cdd:pfam09770 217 APAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHpgQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPV- 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 913 SGQPQQNLYHPgaltgtppSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVtQAHvqtgitaappphpgaphP 992
Cdd:pfam09770 296 PVQPTQILQNP--------NRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPI-ITH-----------------P 349
|
....*.
gi 578828458 993 PQVMLL 998
Cdd:pfam09770 350 QQLAQL 355
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
658-962 |
1.36e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 49.26 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 658 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPrthSTPSIPVLTagqsGLYSPQYISYIPQIH-------MGPAVQ 730
Cdd:pfam09770 98 EQVRFNRQQPAARAAQSSAQPPASSLPQYQYASQQS---QQPSKPVRT----GYEKYKEPEPIPDLQvdaslwgVAPKKA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 731 APQMYPYPVSNSVPGQQGKYR---------------GAKGSLPPQRSDQHQPASAppmmqaaaaagpplvaatPYSSYIP 795
Cdd:pfam09770 171 AAPAPAPQPAAQPASLPAPSRkmmsleeveaamraqAKKPAQQPAPAPAQPPAAP------------------PAQQAQQ 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 796 YnpQQFPGQPAMMQPMAHYPSQPVFAPmlqsnprmltSGSHPQAIVssstpQYPSAEQPTPqalyatvhqsyphhatqlh 875
Cdd:pfam09770 233 Q--QQFPPQIQQQQQPQQQPQQPQQHP----------GQGHPVTIL-----QRPQSPQPDP------------------- 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 876 aHQPQPattPTGSQPQSQHAAPSPVQQHQAGQAPHLGSgqPQQNLYHPGALTGTPPslPPGPSAQSPQSSFPQPAAVYAi 955
Cdd:pfam09770 277 -AQPSI---QPQAQQFHQQPPPVPVQPTQILQNPNRLS--AARVGYPQNPQPGVQP--APAHQAHRQQGSFGRQAPIIT- 347
|
....*..
gi 578828458 956 HHQQLPH 962
Cdd:pfam09770 348 HPQQLAQ 354
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
674-1058 |
1.74e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 1.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 674 PTKPLLSVNKSTSTPTSPGPrTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRG 752
Cdd:PHA03247 2595 SARPRAPVDDRGDPRGPAPP-SPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRaRRLGRA 2673
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 753 AKGSLPPQRSdqHQPASAPPMMQAAAAAGPPLVAATPYssyiPYNPQQFPGQPAMMQPMAHYPSQPVfAPMLQSNPRMLT 832
Cdd:PHA03247 2674 AQASSPPQRP--RRRAARPTVGSLTSLADPPPPPPTPE----PAPHALVSATPLPPGPAAARQASPA-LPAAPAPPAVPA 2746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 833 SGSHPQAIVSSSTPQYPSA-EQPTPQALYATVhqsyPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAPhl 911
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAGpPAPAPPAAPAAG----PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP-- 2820
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 912 gSGQPQQNLYHPGALTGTPPSLPPGPSAQS------------------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 973
Cdd:PHA03247 2821 -AASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggsvapggdvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESFA 2899
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 974 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRI 1053
Cdd:PHA03247 2900 LPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRV 2979
|
....*
gi 578828458 1054 PLSDP 1058
Cdd:PHA03247 2980 PQPAP 2984
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
876-952 |
3.68e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.38 E-value: 3.68e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578828458 876 AHQPQPATTPTGSQPQSqHAAPSPVQQHQAGQAphlgSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 952
Cdd:PRK14971 389 APQPSAAAAASPSPSQS-SAAAQPSAPQSATQP----AGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPV 460
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
740-1058 |
3.67e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 740 SNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPV 819
Cdd:pfam03154 145 SPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQST 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 820 FAPM------LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP-ATTPTGSQPQS 892
Cdd:pfam03154 225 AAPHtliqqtPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPvPPQPFPLTPQS 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 893 QHA----APSPVQQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSS----FPQPAAVYAIHHQQLPHGF 964
Cdd:pfam03154 305 SQSqvppGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTpipqLPNPQSHKHPPHLSGPSPF 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 965 TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLhpPQSHGGPPQGAVP-----QSGVPALSASTPSPYPYIGHPQGEQP 1039
Cdd:pfam03154 385 QMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQQLPPPPAQPpvltqSQSLPPPAASHPPTSGLHQVPSQSPF 462
|
330
....*....|....*....
gi 578828458 1040 GQAPGFPGGADDRIPLSDP 1058
Cdd:pfam03154 463 PQHPFVPGGPPPITPPSGP 481
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
374-702 |
3.74e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 41.21 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 374 PGLSSLPPRGPHHLDNSS----PGPGSEARGINGGPSRMSP----KAQRPLRGAKTLSSP--SNRPSGETSVPPPPaapp 443
Cdd:PTZ00449 514 PEASGLPPKAPGDKEGEEgeheDSKESDEPKEGGKPGETKEgevgKKPGPAKEHKPSKIPtlSKKPEFPKDPKHPK---- 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 444 flpvgRMYPPRSPKS--AAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPgVGSISPASPKISLAPTDVKE-LSTKEP 520
Cdd:PTZ00449 590 -----DPEEPKKPKRprSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRP-PPPQRPSSPERPEGPKIIKSpKPPKSP 663
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 521 GRTLEP---QELARIAGKVPGLQNEQKRFQL--EELRKFGAQFKLQPSSSPENSLDPFPPRIlkeepkgkekEVDGLLTS 595
Cdd:PTZ00449 664 KPPFDPkfkEKFYDDYLDAAAKSKETKTTVVldESFESILKETLPETPGTPFTTPRPLPPKL----------PRDEEFPF 733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 596 EPMGSPVSsktESVSDKE-DKPPLAPSggtegpeqpPPPCPSQTGSPPVGLIKGEDKDEGPVAEqvkksTLNPNAKEFNP 674
Cdd:PTZ00449 734 EPIGDPDA---EQPDDIEfFTPPEEER---------TFFHETPADTPLPDILAEEFKEEDIHAE-----TGEPDEAMKRP 796
|
330 340
....*....|....*....|....*...
gi 578828458 675 TKPllsvnkSTSTPTSPGprTHstPSIP 702
Cdd:PTZ00449 797 DSP------SEHEDKPPG--DH--PSLP 814
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
821-958 |
5.94e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 40.56 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 821 APMLQSNPRMLTSGSHPQaivssstPQYpsaEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPV 900
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQ-------PPY---YGQGPQQQFNGQPLGWPRMSMMPTPMGPGGPLRPNGLAPMNAVRAPSRN 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 578828458 901 QQHQAGQAPhlgsgqpqqnlyhpgaltgtPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 958
Cdd:TIGR01628 450 AQNAAQKPP--------------------MQPVMYPPNYQSLPLSQDLPQPQSTASQG 487
|
|
| PRK10927 |
PRK10927 |
cell division protein FtsN; |
847-951 |
6.12e-03 |
|
cell division protein FtsN;
Pssm-ID: 236797 [Multi-domain] Cd Length: 319 Bit Score: 40.05 E-value: 6.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 847 QYPSAEQpTPQALYATVH-QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQhQAGQAPHLGSGQPQQNLYHPGA 925
Cdd:PRK10927 138 EVPWNEQ-TPEQRQQTLQrQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQA-QPRQSKPASTQQPYQDLLQTPA 215
|
90 100
....*....|....*....|....*..
gi 578828458 926 LTGTPPSLP-PGPSAQSPQSsfPQPAA 951
Cdd:PRK10927 216 HTTAQSKPQqAAPVTRAADA--PKPTA 240
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
834-952 |
7.39e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 40.35 E-value: 7.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 834 GSHPQAIVSSSTPQYPSAeQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQ-PQSQHAAPSPVQQHQAGQAPHLG 912
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAA-APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAgNAPAGGAPSPPPAAAPSAQPAPA 469
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 578828458 913 SGQPQQNLYHPGAltGTPPSLPPGPSAQSPQSSFPQPAAV 952
Cdd:PRK07764 470 PAAAPEPTAAPAP--APPAAPAPAAAPAAPAAPAAPAGAD 507
|
|
| Herpes_TAF50 |
pfam03326 |
Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 ... |
664-923 |
7.87e-03 |
|
Herpesvirus transcription activation factor (transactivator); This family includes EBV BRLF1 and similar ORF 50 proteins from other herpesviruses.
Pssm-ID: 308764 [Multi-domain] Cd Length: 568 Bit Score: 40.07 E-value: 7.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 664 TLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYipQIHMGPAVQAPQMYPYPvsnsv 743
Cdd:pfam03326 310 TLVPIAGSTGVTEVVSYGHNSTSPSSTPCPSTAVTEADHQTEPEVPWIATAHQESD--QRPIGPGPEKPTFLPPV----- 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 744 pgqqGKYRGAKGsLPPQRSDQHQPAsappmmQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPammqpmahypsqpvfapm 823
Cdd:pfam03326 383 ----GGKQFFQG-LRDSRSTSFLTA------PEATSAISDVFQGTEVCQPKRIRALHPPGSP------------------ 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578828458 824 lqSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT--VHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPvQ 901
Cdd:pfam03326 434 --SANRPLPSSLAPTPTGPVHEPGSSLTPATVPQPLDAApvATPEASHELQPPDEETPQPLDEDQALCGQQDASHPPP-R 510
|
250 260
....*....|....*....|..
gi 578828458 902 QHQAGQAPHLGSGQPQQNLYHP 923
Cdd:pfam03326 511 GQLDELTTTLESMTEDLNLDSP 532
|
|
| |
