|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-319 |
3.71e-171 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 477.24 E-value: 3.71e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 1 MPNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 81 SASRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEn 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR--PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKS- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 161 iNEWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADK 240
Cdd:COG0462 158 -KDLEDLVVVSPDVGGVKR---ARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEA 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688553848 241 LVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKiKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS 319
Cdd:COG0462 234 LKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-318 |
1.35e-160 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 450.34 E-value: 1.35e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASAS 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 84 RVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENinE 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKAR--SRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--N 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 164 WKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVS 243
Cdd:PRK01259 157 LENLVVVSPDVGGVVR---ARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKE 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688553848 244 AGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PRK01259 234 RGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-319 |
2.09e-152 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 429.78 E-value: 2.09e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 83 SRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIn 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFK--SREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 163 eWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERK-KANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKL 241
Cdd:TIGR01251 158 -LDNPVVVSPDAGGVER---AKKVADALGCPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEIL 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688553848 242 VSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEdkiKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS 319
Cdd:TIGR01251 234 KSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-122 |
3.71e-71 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 216.13 E-value: 3.71e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASAS 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 688553848 84 RVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAG 122
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDK--PREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-279 |
2.28e-21 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 87.84 E-value: 2.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 149 AEPAVLKWIKENIneWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRM------VLVGDVKDRVAI 222
Cdd:cd06223 1 AGRLLAEEIREDL--LEPDVVVGILRGGLPL---AAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVL 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 688553848 223 LVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAisRINNANFEAVVVTNT 279
Cdd:cd06223 76 LVDDVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-319 |
3.71e-171 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 477.24 E-value: 3.71e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 1 MPNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIA 80
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 81 SASRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEn 160
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFR--PREPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKS- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 161 iNEWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADK 240
Cdd:COG0462 158 -KDLEDLVVVSPDVGGVKR---ARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEA 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688553848 241 LVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKiKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS 319
Cdd:COG0462 234 LKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEE-KRCDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
4-318 |
1.35e-160 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 450.34 E-value: 1.35e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASAS 83
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 84 RVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENinE 163
Cdd:PRK01259 81 RITAVIPYFGYARQDRKAR--SRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--N 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 164 WKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVS 243
Cdd:PRK01259 157 LENLVVVSPDVGGVVR---ARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKE 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688553848 244 AGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PRK01259 234 RGAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
4-319 |
2.09e-152 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 429.78 E-value: 2.09e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIV-QSGCGEINDNLMELLIMINACKIASA 82
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 83 SRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIn 162
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFK--SREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKI- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 163 eWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERK-KANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKL 241
Cdd:TIGR01251 158 -LDNPVVVSPDAGGVER---AKKVADALGCPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEIL 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688553848 242 VSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEdkiKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS 319
Cdd:TIGR01251 234 KSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHE---KHKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
13-318 |
1.98e-111 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 325.50 E-value: 1.98e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 13 PDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCF 92
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 93 PYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENINEWKNCTIVSP 172
Cdd:PLN02369 81 GYARADRKTQ--GRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 173 DAGGAKRcggVTSIADRL-NVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKVYA 251
Cdd:PLN02369 159 DVGGVAR---ARAFAKKLsDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYA 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688553848 252 ILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKiKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PLN02369 236 CATHAVFSPPAIERLSSGLFQEVIVTNTIPVSEK-NYFPQLTVLSVANLLGETIWRVHDDCSVSSIF 301
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
2-318 |
4.17e-110 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 322.65 E-value: 4.17e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 2 PNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIAS 81
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 82 ASRVTAVIPCFPYARQDKKDKvGSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIkeni 161
Cdd:PRK04923 85 AASVTAVIPYFGYSRQDRRMR-SSRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADI---- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 162 neWK-----NCTIVSPDAGGAKRcggVTSIADRL-NVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVC 235
Cdd:PRK04923 160 --WRaygtdNLIVVSPDVGGVVR---ARAVAKRLdDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLC 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 236 HAADKLVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVS 315
Cdd:PRK04923 235 AAAAALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVS 314
|
...
gi 688553848 316 YLF 318
Cdd:PRK04923 315 SLY 317
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
4-318 |
1.37e-108 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 319.38 E-value: 1.37e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASAS 83
Cdd:PRK02812 22 LRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 84 RVTAVIPCFPYARQDKkdKVGSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEniNE 163
Cdd:PRK02812 102 QITAVIPYYGYARADR--KTAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLAS--KN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 164 WKNCTIVSPDAGGAKRcggVTSIADRLN-VDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLV 242
Cdd:PRK02812 178 LEDIVVVSPDVGGVAR---ARAFAKKLNdAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLR 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 688553848 243 SAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKiKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PRK02812 255 KEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPVPEE-RRFPQLKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
1-318 |
8.52e-108 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 321.05 E-value: 8.52e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 1 MPNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIA 80
Cdd:PTZ00145 117 MENAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 81 SASRVTAVIPCFPYARQDKKdkVGSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFD--IPVDNLYAEPAVLKWIK 158
Cdd:PTZ00145 197 SAKKITAVIPYYGYARQDRK--LSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLIGLDYFT 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 159 ENinEWKNCTIVSPDAGGAKRcggVTSIADRLN------VDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCG 232
Cdd:PTZ00145 275 KK--DLYKPVIVSPDAGGVYR---ARKFQDGLNhrgisdCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSG 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 233 TVCHAADKLVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGE 312
Cdd:PTZ00145 350 TLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKE 429
|
....*.
gi 688553848 313 SVSYLF 318
Cdd:PTZ00145 430 SLNDLF 435
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
3-318 |
2.53e-107 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 315.58 E-value: 2.53e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 3 NIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASA 82
Cdd:PRK02269 5 DLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 83 SRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIN 162
Cdd:PRK02269 85 ESINVVMPYYGYARQDRKAR--SREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 163 EWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERK--KANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADK 240
Cdd:PRK02269 163 VGDDVVVVSPDHGGVTR---ARKLAQFLKTPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 241 LVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTI--PQEdkiKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PRK02269 240 LAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIylPEE---RLIDKIEQISIADLLGEAIIRIHEKRPLSPLF 316
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
15-318 |
5.84e-107 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 314.19 E-value: 5.84e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 15 LSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPY 94
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 95 ARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENINEwKNCTIVSPDA 174
Cdd:PRK03092 81 ARQDKKHR--GREPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVVSPDA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 175 GGAKrcggVTSI-ADRL-NVDFALIHKER--KKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKVY 250
Cdd:PRK03092 158 GRVR----VAEQwADRLgGAPLAFIHKTRdpTVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVI 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688553848 251 AILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKiKHCSKIQVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:PRK03092 234 IAATHGVLSGPAAERLKNCGAREVVVTDTLPIPEE-KRFDKLTVLSIAPLLARAIREVFEDGSVTSLF 300
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
2-322 |
5.10e-92 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 277.01 E-value: 5.10e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 2 PNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIAS 81
Cdd:PRK02458 8 KQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 82 ASRVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENI 161
Cdd:PRK02458 88 ANTVNVVLPYFGYARQDRIAK--PREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 162 NEWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVlVGDVKDRVAILVDDMADTCGTVCHAADKL 241
Cdd:PRK02458 166 LSGSDVVVVSPKNSGIKR---ARSLAEYLDAPIAIIDYAQDDSEREEGYI-IGDVAGKKAILIDDILNTGKTFAEAAKIV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 242 VSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKhcSKIQVIDISMILAEAIRRTHNGESVSYLFSHV 321
Cdd:PRK02458 242 EREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKERVP--KNVTYLSASELIADAIIRIHERKPLSPLFAYN 319
|
.
gi 688553848 322 P 322
Cdd:PRK02458 320 K 320
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
6-319 |
3.78e-80 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 246.75 E-value: 3.78e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 6 IFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRV 85
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 86 TAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEnINEWK 165
Cdd:PRK00553 92 TAILPYYGYARQDRKTA--GREPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLE-LLGKK 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 166 NCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSAG 245
Cdd:PRK00553 169 DLVVVSPDYGGVKR---ARLIAESLELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQK 245
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 688553848 246 AIKVYAILTHGIFSGPAISRINNANFEAVV----VTNTIPQEdKIKHCSKIQVIDISMILAEAIRRTHNGESVSYLFS 319
Cdd:PRK00553 246 AKKVCVMATHGLFNKNAIQLFDEAFKKKLIdklfVSNSIPQT-KFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYT 322
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
4-122 |
3.71e-71 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 216.13 E-value: 3.71e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 4 IKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASAS 83
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 688553848 84 RVTAVIPCFPYARQDKKDKvgSRAPISAKLVANMLSVAG 122
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDK--PREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
5-307 |
1.80e-62 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 199.75 E-value: 1.80e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 5 KIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEiNDNLMELLIMINACKIASASR 84
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 85 VTAVIPCFPYARQDKKDKVGSraPISAKLVANMLSVAGaDHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENINew 164
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFKPGE--PISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKLD-- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 165 kNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSA 244
Cdd:PRK00934 155 -DPLVLAPDKGALEL---AKEAAEILGCEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQ 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 688553848 245 GAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPqedkikhcSKIQVIDISMILAEAIRR 307
Cdd:PRK00934 231 GAKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLE--------SEVSKISVAPLIADLLKK 285
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
163-318 |
1.90e-43 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 147.66 E-value: 1.90e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 163 EWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKA--NEVDR----------------------------MVL 212
Cdd:pfam14572 1 DYRNAVIVARSPGSAKR---ATSFAERLRLGIAVIHGEQKEAesDEVDGrqspppyrsrtvsrslglpeiipkekppMTV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 213 VGDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKI 292
Cdd:pfam14572 78 VGDVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKI 157
|
170 180
....*....|....*....|....*.
gi 688553848 293 QVIDISMILAEAIRRTHNGESVSYLF 318
Cdd:pfam14572 158 KTIDISQLIAEAIRRIHNGESMSYLF 183
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
14-307 |
1.10e-41 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 146.62 E-value: 1.10e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 14 DLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSgCGEINDNLMELLIMINACKIASASRVTAVIPCFP 93
Cdd:PRK07199 13 AAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCS-LDRPDEKLLPLLFAAEAARELGARRVGLVAPYLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 94 YARQDKKDKVGSraPISAKLVANMLSvAGADHIITMD--LH-ASQIQGFFDIPVDNLYAEPAVLKWIKENINEWkncTIV 170
Cdd:PRK07199 92 YMRQDIAFHPGE--AISQRHFARLLS-GSFDRLVTVDphLHrYPSLSEVYPIPAVVLSAAPAIAAWIRAHVPRP---LLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 171 SPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDrmVLVGDV---KDRVAILVDDMADTCGTVCHAADKLVSAGAI 247
Cdd:PRK07199 166 GPDEESEQW---VAAVAERAGAPHAVLRKTRHGDRDVE--ISLPDAapwAGRTPVLVDDIVSTGRTLIEAARQLRAAGAA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 248 KVYAILTHGIFSGPAISRINNANFEAVVVTNTIPqedkikHCSkiQVIDISMILAEAIRR 307
Cdd:PRK07199 241 SPDCVVVHALFAGDAYSALAAAGIARVVSTDTVP------HPS--NAISLAPLLAEALRR 292
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
29-317 |
7.16e-37 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 135.85 E-value: 7.16e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 29 KVVTKKFSNQETCVEIGESVRGEDVYIVQ---------SGCGE-----INDNLMELLIMINACKiASASRVTAVIPCFPY 94
Cdd:PRK06827 56 PAKFIRFSNGEAKGEILESVRGKDIYILQdvgnysvtyNMFGEknhmsPDDHFQDLKRTIDAIR-GKARRITVIMPFLYE 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 95 ARQDKKDkvgSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDI-PVDNLYAEPAVLKWIKENINE----WKNCTI 169
Cdd:PRK06827 135 SRQHKRK---GRESLDCALALQELEELGVDNIITFDAHDPRIENAIPLmGFENLYPSYQIIKALLKNEKDleidKDHLMV 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 170 VSPDAGGAKRcggVTSIADRLNVDFALIHKERK-------KANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLV 242
Cdd:PRK06827 212 ISPDTGAMDR---AKYYASVLGVDLGLFYKRRDysrvvngRNPIVAHEFLGRDVEGKDVLIVDDMIASGGSMIDAAKELK 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688553848 243 SAGAIKVYAILTHGIFSGpAISRINNAN----FEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVSYL 317
Cdd:PRK06827 289 SRGAKKIIVAATFGFFTN-GLEKFDKAYeegyFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARIIDALNHDVSLSKL 366
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
149-279 |
2.28e-21 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 87.84 E-value: 2.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 149 AEPAVLKWIKENIneWKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKANEVDRM------VLVGDVKDRVAI 222
Cdd:cd06223 1 AGRLLAEEIREDL--LEPDVVVGILRGGLPL---AAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVL 75
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 688553848 223 LVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAisRINNANFEAVVVTNT 279
Cdd:cd06223 76 LVDDVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
3-282 |
1.35e-09 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 58.55 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 3 NIKIFSGSSHPDLSQKIADRLG-LELGKVVTKKFSNQETCVEIG--ESVRGEDVYIVQSGcgEINDNLMELLIMINACKI 79
Cdd:PLN02297 16 QVHLFYCEETEELARKIAAESDaIELGSINWRKFPDGFPNLFINnaHGIRGQHVAFLASF--SSPAVIFEQLSVIYALPK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 80 ASASRVTAVIPCFPYARQDKKDKVGSRApiSAKLVANMLS-----VAGADHIITMDLHASQIQGFFDIPVDNLYAE--PA 152
Cdd:PLN02297 94 LFVASFTLVLPFFPTGTSERVEREGDVA--TAFTLARILSnipisRGGPTSLVIFDIHALQERFYFGDNVLPCFESgiPL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 153 VLKWIKEnINEWKNCTIVSPDAGGAKRcggvtsiadrlnvdfalIHKERKKANEV---------DRMVLV--GDVKDRVA 221
Cdd:PLN02297 172 LKKRLQQ-LPDSDNIVIAFPDDGAWKR-----------------FHKQFEHFPMVvctkvregdKRIVRIkeGNPAGRHV 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 688553848 222 ILVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAISRINNAN------FEAVVVTNTIPQ 282
Cdd:PLN02297 234 VIVDDLVQSGGTLIECQKVLAAHGAAKVSAYVTHGVFPNESWERFTHDNggpeagFAYFWITDSCPQ 300
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
143-249 |
2.97e-06 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 46.20 E-value: 2.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 143 PVDNLYAEPAVLKWIKE---NINE---WKNCTIVSPDAGGAKRcggVTSIADRLNVDFALIHKERKKAN---EVDRMVLV 213
Cdd:pfam00156 1 SVDEILDNPAILKAVARlaaQINEdygGKPDVVVGILRGGLPF---AGILARRLDVPLAFVRKVSYNPDtseVMKTSSAL 77
|
90 100 110
....*....|....*....|....*....|....*.
gi 688553848 214 GDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKV 249
Cdd:pfam00156 78 PDLKGKTVLIVDDILDTGGTLLKVLELLKNVGPKEV 113
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
183-278 |
5.79e-03 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 37.44 E-value: 5.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688553848 183 VTSIADRLNVDFALIhkeRKKANEVDRM-VLVGDVK--DRVAIlVDDMADTCGTVCHAADKLVSAGA--IKVYAILTHGi 257
Cdd:COG0461 78 AAAVARALGLPAIFV---RKEAKDHGTGgQIEGGLLpgERVLV-VEDVITTGGSVLEAVEALREAGAevVGVAVIVDRE- 152
|
90 100
....*....|....*....|.
gi 688553848 258 fsGPAISRINNANFEAVVVTN 278
Cdd:COG0461 153 --EGAAENLEEAGVPLHSLLT 171
|
|
| |
