evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X2 [Mus musculus]
Protein Classification
ECSIT and ECSIT_C domain-containing protein( domain architecture ID 12069161)
ECSIT and ECSIT_C domain-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| ECSIT | pfam06239 | Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a ... |
73-266 | 3.95e-116 | ||||
Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a consequence of signaling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT plays an important role in signalling to NF-kappaB, functioning as the intermediate in the signaling pathways between TRAF-6 and MEKK-1. : Pssm-ID: 461857 Cd Length: 191 Bit Score: 335.09 E-value: 3.95e-116
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| ECSIT_C super family | cl20706 | C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the ... |
269-350 | 7.20e-23 | ||||
C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the evolutionarily conserved signaling intermediate in Toll pathway protein, an adapter protein of the Toll-like and IL-1 receptor signaling pathway, which is involved in the activation of NF-kappa-B via MAP3K1. This domain is missing in isoform 2. Fold recognition suggests that this domain may be distantly homologous to the pleckstrin homology domain The actual alignment was detected with superfamily member pfam14784: Pssm-ID: 464316 Cd Length: 131 Bit Score: 92.76 E-value: 7.20e-23
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| Name | Accession | Description | Interval | E-value | ||||
| ECSIT | pfam06239 | Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a ... |
73-266 | 3.95e-116 | ||||
Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a consequence of signaling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT plays an important role in signalling to NF-kappaB, functioning as the intermediate in the signaling pathways between TRAF-6 and MEKK-1. Pssm-ID: 461857 Cd Length: 191 Bit Score: 335.09 E-value: 3.95e-116
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| ECSIT_C | pfam14784 | C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the ... |
269-350 | 7.20e-23 | ||||
C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the evolutionarily conserved signaling intermediate in Toll pathway protein, an adapter protein of the Toll-like and IL-1 receptor signaling pathway, which is involved in the activation of NF-kappa-B via MAP3K1. This domain is missing in isoform 2. Fold recognition suggests that this domain may be distantly homologous to the pleckstrin homology domain Pssm-ID: 464316 Cd Length: 131 Bit Score: 92.76 E-value: 7.20e-23
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| Name | Accession | Description | Interval | E-value | ||||
| ECSIT | pfam06239 | Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a ... |
73-266 | 3.95e-116 | ||||
Evolutionarily conserved signalling intermediate in Toll pathway; Activation of NF-kappaB as a consequence of signaling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT plays an important role in signalling to NF-kappaB, functioning as the intermediate in the signaling pathways between TRAF-6 and MEKK-1. Pssm-ID: 461857 Cd Length: 191 Bit Score: 335.09 E-value: 3.95e-116
|
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| ECSIT_C | pfam14784 | C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the ... |
269-350 | 7.20e-23 | ||||
C-terminal domain of the ECSIT protein; This family represents the C-terminal domain of the evolutionarily conserved signaling intermediate in Toll pathway protein, an adapter protein of the Toll-like and IL-1 receptor signaling pathway, which is involved in the activation of NF-kappa-B via MAP3K1. This domain is missing in isoform 2. Fold recognition suggests that this domain may be distantly homologous to the pleckstrin homology domain Pssm-ID: 464316 Cd Length: 131 Bit Score: 92.76 E-value: 7.20e-23
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