WD repeat-containing protein 31 isoform X3 [Homo sapiens]
WD40 repeat domain-containing protein( domain architecture ID 1000017)
WD40 repeat domain-containing protein similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
WD40 super family | cl29593 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
61-325 | 3.42e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. The actual alignment was detected with superfamily member cd00200: Pssm-ID: 453027 [Multi-domain] Cd Length: 289 Bit Score: 121.67 E-value: 3.42e-32
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Name | Accession | Description | Interval | E-value | |||||
WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
61-325 | 3.42e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 121.67 E-value: 3.42e-32
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
88-318 | 1.20e-25 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 106.71 E-value: 1.20e-25
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
110-149 | 6.96e-07 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.38 E-value: 6.96e-07
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WD40 | pfam00400 | WD domain, G-beta repeat; |
111-149 | 4.18e-06 | |||||
WD domain, G-beta repeat; Pssm-ID: 425662 [Multi-domain] Cd Length: 39 Bit Score: 43.10 E-value: 4.18e-06
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PTZ00421 | PTZ00421 | coronin; Provisional |
90-241 | 6.64e-06 | |||||
coronin; Provisional Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 47.58 E-value: 6.64e-06
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Name | Accession | Description | Interval | E-value | |||||
WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
61-325 | 3.42e-32 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 121.67 E-value: 3.42e-32
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WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
61-285 | 3.47e-26 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 105.49 E-value: 3.47e-26
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
88-318 | 1.20e-25 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 106.71 E-value: 1.20e-25
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WD40 | cd00200 | WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
113-325 | 4.06e-23 | |||||
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 97.02 E-value: 4.06e-23
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
84-308 | 4.61e-19 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 87.84 E-value: 4.61e-19
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
88-300 | 1.68e-18 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 85.91 E-value: 1.68e-18
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WD40 | COG2319 | WD40 repeat [General function prediction only]; |
29-332 | 1.17e-17 | |||||
WD40 repeat [General function prediction only]; Pssm-ID: 225201 [Multi-domain] Cd Length: 466 Bit Score: 83.60 E-value: 1.17e-17
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
110-149 | 6.96e-07 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.38 E-value: 6.96e-07
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WD40 | pfam00400 | WD domain, G-beta repeat; |
111-149 | 4.18e-06 | |||||
WD domain, G-beta repeat; Pssm-ID: 425662 [Multi-domain] Cd Length: 39 Bit Score: 43.10 E-value: 4.18e-06
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PTZ00421 | PTZ00421 | coronin; Provisional |
90-241 | 6.64e-06 | |||||
coronin; Provisional Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 47.58 E-value: 6.64e-06
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PLN00181 | PLN00181 | protein SPA1-RELATED; Provisional |
134-306 | 3.62e-04 | |||||
protein SPA1-RELATED; Provisional Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 42.38 E-value: 3.62e-04
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
242-285 | 2.84e-03 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 34.98 E-value: 2.84e-03
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WD40 | smart00320 | WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
152-191 | 6.90e-03 | |||||
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain. Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 33.83 E-value: 6.90e-03
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WD40 | pfam00400 | WD domain, G-beta repeat; |
243-285 | 7.14e-03 | |||||
WD domain, G-beta repeat; Pssm-ID: 425662 [Multi-domain] Cd Length: 39 Bit Score: 33.86 E-value: 7.14e-03
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Blast search parameters | ||||
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