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Conserved domains on  [gi|767978960|ref|XP_011519424|]
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protein O-mannosyl-transferase TMTC4 isoform X1 [Homo sapiens]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
369-443 4.16e-39

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


:

Pssm-ID: 429980  Cd Length: 75  Bit Score: 138.82  E-value: 4.16e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767978960  369 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 443
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
558-794 4.22e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 94.53  E-value: 4.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 558 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 633
Cdd:COG0457   22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 634 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 709
Cdd:COG0457  102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 710 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 788
Cdd:COG0457  182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                 ....*.
gi 767978960 789 SLQLDP 794
Cdd:COG0457  262 ALELDP 267
 
Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
369-443 4.16e-39

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


Pssm-ID: 429980  Cd Length: 75  Bit Score: 138.82  E-value: 4.16e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767978960  369 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 443
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
558-794 4.22e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 94.53  E-value: 4.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 558 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 633
Cdd:COG0457   22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 634 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 709
Cdd:COG0457  102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 710 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 788
Cdd:COG0457  182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                 ....*.
gi 767978960 789 SLQLDP 794
Cdd:COG0457  262 ALELDP 267
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
546-794 1.31e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 81.28  E-value: 1.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  546 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 625
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  626 FAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILL 705
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  706 DNT----------------------------------GNLAQAEAVGREALELIPNDHSLMfSLANVLGKSQKYKESEAL 751
Cdd:TIGR02917 680 LAAkrtesakkiakslqkqhpkaalgfelegdlylrqKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKT 758
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 767978960  752 FLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:TIGR02917 759 LEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
573-655 5.35e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 57.56  E-value: 5.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 573 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRT 652
Cdd:NF033920 170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249

                 ...
gi 767978960 653 AIK 655
Cdd:NF033920 250 ALA 252
TPR_19 pfam14559
Tetratricopeptide repeat;
573-631 1.14e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 46.42  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767978960  573 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 631
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
561-621 1.98e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 48.51  E-value: 1.98e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767978960 561 VHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNIL-------KERNELQEAEELLSLAVQ 621
Cdd:PRK02603  74 ILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAE 141
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
676-794 5.51e-06

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 48.70  E-value: 5.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 676 RHVDALNA----WRNA-----TVLKPEHS------LAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 740
Cdd:NF033920 122 RHRLSFSTfertWARAdywalVVLPPGQLpatadpLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAY 201
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767978960 741 KSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:NF033920 202 AAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
627-660 1.14e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.14e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 767978960   627 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 660
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
369-443 4.16e-39

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


Pssm-ID: 429980  Cd Length: 75  Bit Score: 138.82  E-value: 4.16e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767978960  369 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 443
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
558-794 4.22e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 94.53  E-value: 4.22e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 558 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 633
Cdd:COG0457   22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 634 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 709
Cdd:COG0457  102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 710 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 788
Cdd:COG0457  182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                 ....*.
gi 767978960 789 SLQLDP 794
Cdd:COG0457  262 ALELDP 267
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
558-790 1.54e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 92.99  E-value: 1.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 558 NAKVHYNIGKNLADKGNQTAAIRYYREAVR--LNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGI 635
Cdd:COG0457   58 LAGLLLLLALALLKLGRLEEALELLEKALEleLLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAL 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 636 -VQNSLKRFEAAEQSYRTAIK---HRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSL-AWNNMIILLDNTGN 710
Cdd:COG0457  138 gALYELGDYEEALELYEKALEldpELNELAEALLALGALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGK 217
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 711 LAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNaasyHGNLAVLYhrWGHLDLAKKHYEISL 790
Cdd:COG0457  218 YEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEKALELDPD----LYNLGLAL--LLLLAEALELLEKAD 291
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
575-815 4.16e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 88.75  E-value: 4.16e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 575 QTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQP--DFAAAWMNLGIVQNSLKRFEAAEQSYRT 652
Cdd:COG0457    5 LLALAILLEALAKLLAEALALLEAGLALLELLGELAEALELLEEALELLPnsDLAGLLLLLALALLKLGRLEEALELLEK 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 653 AIKHR--RKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNM-IILLDNTGNLAQAEAVGREALELIPNDH 729
Cdd:COG0457   85 ALELEllPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLaLGALYELGDYEEALELYEKALELDPELN 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 730 SL---MFSLANVLGKSQKYKESEALFLKAIKANPN-AASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGL 805
Cdd:COG0457  165 ELaeaLLALGALLEALGRYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLAL 244
                        250
                 ....*....|
gi 767978960 806 LRRKLELMQK 815
Cdd:COG0457  245 LLLELGRYEE 254
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
546-794 1.31e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 81.28  E-value: 1.31e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  546 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 625
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  626 FAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILL 705
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  706 DNT----------------------------------GNLAQAEAVGREALELIPNDHSLMfSLANVLGKSQKYKESEAL 751
Cdd:TIGR02917 680 LAAkrtesakkiakslqkqhpkaalgfelegdlylrqKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKT 758
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 767978960  752 FLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:TIGR02917 759 LEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
524-694 6.41e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 76.04  E-value: 6.41e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 524 LGILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKN-LADKGNQTAAIRYYREAVRLNPK---YVHAMNNL 599
Cdd:COG0457   94 LAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLALGaLYELGDYEEALELYEKALELDPElneLAEALLAL 173
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 600 GNILKERNELQEAEELLSLAVQIQPDFAA-AWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHV 678
Cdd:COG0457  174 GALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYE 253
                        170
                 ....*....|....*.
gi 767978960 679 DALNAWRNATVLKPEH 694
Cdd:COG0457  254 EALEALEKALELDPDL 269
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
548-784 2.73e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.05  E-value: 2.73e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  548 FRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFA 627
Cdd:TIGR02917 624 FKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAA 703
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  628 AAWMNLGIVQNSLKRFEAAEQSYRTAIK-----------HR-------------------RKYPD---CYYNLGRLYADL 674
Cdd:TIGR02917 704 LGFELEGDLYLRQKDYPAAIQAYRKALKrapssqnaiklHRallasgntaeavktleawlKTHPNdavLRTALAELYLAQ 783
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  675 NRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNlAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLK 754
Cdd:TIGR02917 784 KDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRK 862
                         250       260       270
                  ....*....|....*....|....*....|
gi 767978960  755 AIKANPNAASYHGNLAVLYHRWGHLDLAKK 784
Cdd:TIGR02917 863 AVNIAPEAAAIRYHLALALLATGRKAEARK 892
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
572-794 2.52e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 73.96  E-value: 2.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  572 KGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 651
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYR 217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  652 TAIKHRRKYPDCYYNLGRLYADLNR------HVDALNAWRN----ATVLKP-------------EH-----SLAWNNMII 703
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEAGEfeeaekHADALLKKAPnsplAHYLKAlvdfqkknyedarETlqdalKSAPEYLPA 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  704 LL------DNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWG 777
Cdd:TIGR02917 298 LLlagaseYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALG 377
                         250
                  ....*....|....*..
gi 767978960  778 HLDLAKKHYEISLQLDP 794
Cdd:TIGR02917 378 DFEKAAEYLAKATELDP 394
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
551-683 5.71e-13

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 69.29  E-value: 5.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  551 ALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQiQPDF---A 627
Cdd:TIGR02521  57 ALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE-DPLYpqpA 135
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767978960  628 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNA 683
Cdd:TIGR02521 136 RSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAY 191
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
550-794 1.34e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 71.65  E-value: 1.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  550 SALSVCPLN-AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAE-EL---LSL---AVQ 621
Cdd:TIGR02917  12 LALSACGDQsPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEkELrkaLSLgypKNQ 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  622 IQPDFAAAWMNLGIVQNSL----------------------------KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYAD 673
Cdd:TIGR02917  92 VLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglGQLELAQKSYEQALAIDPRSLYAKLGLAQLALA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  674 LNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 753
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAD 251
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 767978960  754 KAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:TIGR02917 252 ALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAP 292
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
545-794 1.53e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 71.27  E-value: 1.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  545 EQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQP 624
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  625 DFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALnAWRNATVLKPEHSLAWNNMI-- 702
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAY-QYLNQILKYAPNSHQARRLLas 337
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  703 ILLDNtGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLA 782
Cdd:TIGR02917 338 IQLRL-GRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEA 416
                         250
                  ....*....|..
gi 767978960  783 KKHYEISLQLDP 794
Cdd:TIGR02917 417 IADLETAAQLDP 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
539-796 2.22e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 70.88  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  539 GEWRSEEQLFRSALSVCPLNakvhYNIGKNLA----DKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEE 614
Cdd:TIGR02917 309 GNLEQAYQYLNQILKYAPNS----HQARRLLAsiqlRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAE 384
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  615 LLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEH 694
Cdd:TIGR02917 385 YLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDN 464
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  695 SLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYH 774
Cdd:TIGR02917 465 ASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYL 544
                         250       260
                  ....*....|....*....|..
gi 767978960  775 RWGHLDLAKKHYEISLQLDPTA 796
Cdd:TIGR02917 545 RTGNEEEAVAWLEKAAELNPQE 566
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
607-815 1.45e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 62.94  E-value: 1.45e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 607 NELQEAEELLSLAVQIQPDFAAAWMNLG-IVQNSLKRFEAAEQSYRTAIKH--RRKYPDCYYNLGRLYADLNRHVDALNA 683
Cdd:COG0457    2 KDLLLALAILLEALAKLLAEALALLEAGlALLELLGELAEALELLEEALELlpNSDLAGLLLLLALALLKLGRLEEALEL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 684 WRNA--TVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLA-NVLGKSQKYKESEALFLKAIKANP 760
Cdd:COG0457   82 LEKAleLELLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAlGALYELGDYEEALELYEKALELDP 161
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767978960 761 ---NAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASG-TKENYGLLRRKLELMQK 815
Cdd:COG0457  162 elnELAEALLALGALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGKYEE 220
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
563-751 2.56e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 58.60  E-value: 2.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 563 YNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKR 642
Cdd:COG5010   70 AKLATALYLRGDADSSLAVLQKSAIAYPKDRELLAAQGKNQIRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGR 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 643 FEAAEQSYRTAIKhrrkypdcyynlgrlyadlnrhvdalnawrnatvLKPEHSLAWNNMIILLDNTGNLAQAEAVGREAL 722
Cdd:COG5010  150 FDEARRAYRQALE----------------------------------LAPNEPSIANNLGMSLLLRGDLEDAETLLLPAY 195
                        170       180
                 ....*....|....*....|....*....
gi 767978960 723 ELIPNDHSLMFSLANVLGKSQKYKESEAL 751
Cdd:COG5010  196 LSPAADSRVRQNLALVVGLQGDFREAEDI 224
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
573-655 5.35e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 57.56  E-value: 5.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 573 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRT 652
Cdd:NF033920 170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249

                 ...
gi 767978960 653 AIK 655
Cdd:NF033920 250 ALA 252
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
536-680 7.47e-09

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 57.43  E-value: 7.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 536 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 615
Cdd:COG3063   46 LQQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLCAQGRPEEAMQQ 125
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767978960 616 LSLAVQiQPDF---AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDA 680
Cdd:COG3063  126 FERALA-DPAYgepSDTLENLGLCALKAGQFDQAEEYLKRALELDPQFPPALLELARLHYKAGDYAPA 192
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
605-764 1.11e-08

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 56.66  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 605 ERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAW 684
Cdd:COG3063   47 QQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLCAQGRPEEAMQQF 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 685 RNATVLK--PEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLK-AIKANPN 761
Cdd:COG3063  127 ERALADPayGEPSDTLENLGLCALKAGQFDQAEEYLKRALELDPQFPPALLELARLHYKAGDYAPARLYLERyQQRGGAQ 206

                 ...
gi 767978960 762 AAS 764
Cdd:COG3063  207 AES 209
YfgC COG4783
Putative Zn-dependent protease, contains TPR repeats [General function prediction only];
583-683 4.55e-08

Putative Zn-dependent protease, contains TPR repeats [General function prediction only];


Pssm-ID: 227122 [Multi-domain]  Cd Length: 484  Bit Score: 56.25  E-value: 4.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 583 REAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPD 662
Cdd:COG4783  330 QPLIAAQPDNPYYLELAGDILLEANKAKEAIERLKKALALDPNSPLLQLNLAQALLKGGKPQEAIRILNRYLFNDPEDPN 409
                         90       100
                 ....*....|....*....|.
gi 767978960 663 CYYNLGRLYADLNRHVDALNA 683
Cdd:COG4783  410 GWDLLAQAYAELGNRAEALLA 430
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
570-818 1.92e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.60  E-value: 1.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  570 ADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQS 649
Cdd:TIGR00990 376 LELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMAT 455
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  650 YRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEavgrealelipndh 729
Cdd:TIGR00990 456 FRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLINKALALFQWK-------------- 521
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  730 slmfslanvlgksQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPT----------ASGT 799
Cdd:TIGR00990 522 -------------QDFIEAENLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAELARTegelvqaisyAEAT 588
                         250       260
                  ....*....|....*....|....*
gi 767978960  800 K------ENYGLLRRKLELMQKKAV 818
Cdd:TIGR00990 589 RtqiqvqEDYPVLASKLQGMLGGLR 613
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
667-784 2.91e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 52.44  E-value: 2.91e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 667 LGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYK 746
Cdd:COG5010  106 QGKNQIRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGRFDEARRAYRQALELAPNEPSIANNLGMSLLLRGDLE 185
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 767978960 747 ESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKK 784
Cdd:COG5010  186 DAETLLLPAYLSPAADSRVRQNLALVVGLQGDFREAED 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
536-680 3.21e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.93  E-value: 3.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  536 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNElQEAEEL 615
Cdd:TIGR02917 747 LASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEY 825
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767978960  616 LSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDA 680
Cdd:TIGR02917 826 AERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEA 890
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
536-794 5.09e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 5.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  536 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAeel 615
Cdd:TIGR02917 374 LALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKA--- 450
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  616 LSLAVQI---QPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNR---------------- 676
Cdd:TIGR02917 451 LAAAKKLekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNpddaiqrfekvltidp 530
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  677 -HVDALNAW-----RNAtvlKPEHSLAWNNMIILLDNT---------------GNLAQAEAVGREALELIPNDHSLMFSL 735
Cdd:TIGR02917 531 kNLRAILALaglylRTG---NEEEAVAWLEKAAELNPQeiepalalaqyylgkGQLKKALAILNEAADAAPDSPEAWLML 607
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767978960  736 ANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
524-646 7.86e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 51.77  E-value: 7.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 524 LGILFINTLRCVLRSGEWRSEEQLFRSALSVCP-LNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNI 602
Cdd:COG0457  166 LAEALLALGALLEALGRYEEALELLEKALKLNPdDDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALL 245
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 767978960 603 LKERNELQEAEELLSLAVQIQPD-FAAAWMNLGIVQNSLKRFEAA 646
Cdd:COG0457  246 LLELGRYEEALEALEKALELDPDlYNLGLALLLLLAEALELLEKA 290
TPR_19 pfam14559
Tetratricopeptide repeat;
573-631 1.14e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 46.42  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767978960  573 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 631
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
640-817 1.40e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 51.00  E-value: 1.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 640 LKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHSLA--WNNMIILLDNTGNLAQAEA 716
Cdd:COG0457    1 LKDLLLALAILLEALAKLLAEALALLEAGLaLLELLGELAEALELLEEALELLPNSDLAglLLLLALALLKLGRLEEALE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 717 VGREALE--LIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLA-VLYHRWGHLDLAKKHYEISLQLD 793
Cdd:COG0457   81 LLEKALEleLLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAlGALYELGDYEEALELYEKALELD 160
                        170       180
                 ....*....|....*....|....
gi 767978960 794 PTASGTKENYGLLRRKLELMQKKA 817
Cdd:COG0457  161 PELNELAEALLALGALLEALGRYE 184
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
509-751 1.63e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  509 LSKHTKKKKLIAAVVLGILFintlRCVLRSGEWRSEEQLFRSALSVCPLNAKVhYNIGKNLADKGNQTAAIRYYREAVRL 588
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEG----DLYLRQKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGNTAEAVKTLEAWLKT 765
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  589 NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEA---AEQSYRTAikhrrkyPDcyy 665
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRAleyAERALKLA-------PN--- 835
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  666 nlgrlyadlnrhvdalnawrNATVLKpehSLAWnnmiiLLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKY 745
Cdd:TIGR02917 836 --------------------IPAILD---TLGW-----LLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRK 887

                  ....*.
gi 767978960  746 KESEAL 751
Cdd:TIGR02917 888 AEARKE 893
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
561-621 1.98e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 48.51  E-value: 1.98e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767978960 561 VHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNIL-------KERNELQEAEELLSLAVQ 621
Cdd:PRK02603  74 ILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAE 141
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
563-625 3.89e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 45.02  E-value: 3.89e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767978960  563 YNIGKNLADKGNQTAAIRYYREAVRLN---PKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 625
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
676-794 5.51e-06

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 48.70  E-value: 5.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 676 RHVDALNA----WRNA-----TVLKPEHS------LAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 740
Cdd:NF033920 122 RHRLSFSTfertWARAdywalVVLPPGQLpatadpLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAY 201
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767978960 741 KSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 794
Cdd:NF033920 202 AAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR_12 pfam13424
Tetratricopeptide repeat;
595-659 6.87e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 44.69  E-value: 6.87e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767978960  595 AMNNLGNILKERNELQEAEELLSLAVQIQ--------PDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 659
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_12 pfam13424
Tetratricopeptide repeat;
625-683 3.14e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 42.76  E-value: 3.14e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767978960  625 DFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPD--------CYYNLGRLYADLNRHVDALNA 683
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGpdhpltatTLLNLGRLYLELGRYEEALEL 67
TPR_12 pfam13424
Tetratricopeptide repeat;
559-625 4.98e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.99  E-value: 4.98e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767978960  559 AKVHYNIGKNLADKGNQTAAIRYYREAVRL--------NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 625
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
ycf3 CHL00033
photosystem I assembly protein Ycf3
563-619 6.37e-05

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 44.23  E-value: 6.37e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767978960 563 YNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNL-------GNILKERNELQEAEELLSLA 619
Cdd:CHL00033  76 YNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMavichyrGEQAIEQGDSEIAEAWFDQA 139
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
743-804 7.68e-05

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 45.11  E-value: 7.68e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767978960 743 QKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYG 804
Cdd:COG3063   49 GDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYG 110
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
536-649 9.33e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 44.73  E-value: 9.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 536 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 615
Cdd:COG5010  111 IRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGRFDEARRAYRQALELAPNEPSIANNLGMSLLLRGDLEDAETL 190
                         90       100       110
                 ....*....|....*....|....*....|....
gi 767978960 616 LSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQS 649
Cdd:COG5010  191 LLPAYLSPAADSRVRQNLALVVGLQGDFREAEDI 224
TPR_12 pfam13424
Tetratricopeptide repeat;
735-792 1.76e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.45  E-value: 1.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767978960  735 LANVLGKSQKYKESEALFLKAIKA--------NPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQL 792
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_19 pfam14559
Tetratricopeptide repeat;
709-772 1.84e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 40.26  E-value: 1.84e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767978960  709 GNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVL 772
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_1 pfam00515
Tetratricopeptide repeat;
627-660 1.84e-04

Tetratricopeptide repeat;


Pssm-ID: 425728 [Multi-domain]  Cd Length: 34  Bit Score: 39.33  E-value: 1.84e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767978960  627 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 660
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
559-591 2.03e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.04  E-value: 2.03e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 767978960  559 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPK 591
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
559-592 2.11e-04

Tetratricopeptide repeat;


Pssm-ID: 425728 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 2.11e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767978960  559 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKY 592
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
665-728 2.26e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.01  E-value: 2.26e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767978960  665 YNLGRLYADLNRHVDALNAWRNAT---VLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPND 728
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
TPR_17 pfam13431
Tetratricopeptide repeat;
581-614 2.27e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 39.06  E-value: 2.27e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767978960  581 YYREAVRLNPKYVHAMNNLGNILKERNELQEAEE 614
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
661-800 3.59e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 3.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  661 PDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 740
Cdd:TIGR02917  22 PEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYL 101
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767978960  741 KSQKYKESEALFLKA-IKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTK 800
Cdd:TIGR02917 102 LQGKFQQVLDELPGKtLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAK 162
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
598-661 4.42e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 4.42e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767978960  598 NLGNILKERNELQEAEELLSLAVQIQ---PDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYP 661
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
TPR_8 pfam13181
Tetratricopeptide repeat;
559-591 4.91e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 38.15  E-value: 4.91e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 767978960  559 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPK 591
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR COG0790
TPR repeat [Signal transduction mechanisms];
572-672 5.54e-04

TPR repeat [Signal transduction mechanisms];


Pssm-ID: 223861 [Multi-domain]  Cd Length: 292  Bit Score: 42.72  E-value: 5.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 572 KGNQTAAIRYYREAVRLNpkYVHAMNNLGNILKE----RNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNS------- 639
Cdd:COG0790   90 SRDKTKAADWYRCAAADG--LAEALFNLGLMYANgrgvPLDLVKALKYYEKAAkLGNVEAALAMYRLGLAYLSglqalav 167
                         90       100       110
                 ....*....|....*....|....*....|...
gi 767978960 640 LKRFEAAEQSYRTAikHRRKYPDCYYNLGRLYA 672
Cdd:COG0790  168 AYDDKKALYLYRKA--AELGNPDAQLLLGRMYE 198
TPR_11 pfam13414
TPR repeat;
566-605 5.94e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 5.94e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 767978960  566 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 605
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
627-761 8.45e-04

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 42.03  E-value: 8.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 627 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLD 706
Cdd:COG3063   35 AKARLQLALGYLQQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLC 114
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767978960 707 NTGNLAQAEAVGREALELiPNDHSLMFSLANvLG----KSQKYKESEALFLKAIKANPN 761
Cdd:COG3063  115 AQGRPEEAMQQFERALAD-PAYGEPSDTLEN-LGlcalKAGQFDQAEEYLKRALELDPQ 171
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
709-810 1.02e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 41.55  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  709 GNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNL-AVLYHRwGHLDLAKKHYE 787
Cdd:TIGR02521  45 GDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYgTFLCQQ-GKYEQAMQQFE 123
                          90       100
                  ....*....|....*....|....*
gi 767978960  788 --ISLQLDPTASGTKENYGLLRRKL 810
Cdd:TIGR02521 124 qaIEDPLYPQPARSLENAGLCALKA 148
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
627-660 1.14e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.14e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 767978960   627 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 660
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
751-784 1.28e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 36.75  E-value: 1.28e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 767978960  751 LFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKK 784
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_19 pfam14559
Tetratricopeptide repeat;
607-670 1.37e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.56  E-value: 1.37e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767978960  607 NELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRL 670
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_11 pfam13414
TPR repeat;
600-637 1.47e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.07  E-value: 1.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 767978960  600 GNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 637
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAY 38
TPR_11 pfam13414
TPR repeat;
639-674 1.62e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.62e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767978960  639 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADL 674
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
559-592 1.81e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.27  E-value: 1.81e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 767978960   559 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKY 592
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
YfgC COG4783
Putative Zn-dependent protease, contains TPR repeats [General function prediction only];
580-728 1.86e-03

Putative Zn-dependent protease, contains TPR repeats [General function prediction only];


Pssm-ID: 227122 [Multi-domain]  Cd Length: 484  Bit Score: 41.62  E-value: 1.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 580 RYYREAVRLNPKYVHAMnnlgnILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 659
Cdd:COG4783  264 PPYNKLDSPDFQLARAR-----IRAKYEALPNQQAADLLAKRSKRGGLAAQYGRALQTYLAGQYDEALKLLQPLIAAQPD 338
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767978960 660 YPdcYYN--LGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPND 728
Cdd:COG4783  339 NP--YYLelAGDILLEANKAKEAIERLKKALALDPNSPLLQLNLAQALLKGGKPQEAIRILNRYLFNDPED 407
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
667-763 2.87e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 226687 [Multi-domain]  Cd Length: 287  Bit Score: 40.44  E-value: 2.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960 667 LGRLYADLNRHVDALNAWRNATVL---KPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQ 743
Cdd:COG4235  162 LGRAYMALGRASDALLAYRNALRLagdNPEILLGLAEALYYQAGQQMTAKARALLRQALALDPANIRALSLLAFAAFEQG 241
                         90       100
                 ....*....|....*....|
gi 767978960 744 KYKESEALFLKAIKANPNAA 763
Cdd:COG4235  242 DYAEAAAAWQMLLDLLPADD 261
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
661-694 3.26e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.89  E-value: 3.26e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 767978960   661 PDCYYNLGRLYADLNRHVDALNAWRNATVLKPEH 694
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
595-623 3.29e-03

Tetratricopeptide repeat;


Pssm-ID: 433156 [Multi-domain]  Cd Length: 42  Bit Score: 35.94  E-value: 3.29e-03
                          10        20
                  ....*....|....*....|....*....
gi 767978960  595 AMNNLGNILKERNELQEAEELLSLAVQIQ 623
Cdd:pfam13374   4 SLNNLANALRAQGRYDEAEELLEEALAIR 32
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
536-592 4.04e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.55  E-value: 4.04e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767978960  536 LRSGEWRSEEQLFRSAL---SVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKY 592
Cdd:pfam13432   8 LRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
TPR_1 pfam00515
Tetratricopeptide repeat;
763-795 4.42e-03

Tetratricopeptide repeat;


Pssm-ID: 425728 [Multi-domain]  Cd Length: 34  Bit Score: 35.48  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 767978960  763 ASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPT 795
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
642-681 5.06e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.16  E-value: 5.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 767978960  642 RFEAAEQSYRTAIKHRRKYPDC---YYNLGRLYADLNRHVDAL 681
Cdd:pfam13432  12 DYDDAAAALEAALARFPESPDAaaaLLLLGLAALRQGRLAEAA 54
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
763-795 5.55e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.55e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 767978960   763 ASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPT 795
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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