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Conserved domains on  [gi|768021900|ref|XP_011528088|]
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radial spoke head 1 homolog isoform X1 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-165 1.71e-35

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 128.54  E-value: 1.71e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642  124 GGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNG 203

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768021900  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642  204 QRHGQGTYTYADGDRYEGEFKNGKRHGQGTLTYAD-GDRYEGEFKNGKRHGQGTMTYADgSVYEGEWKN 271
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-165 1.71e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 128.54  E-value: 1.71e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642  124 GGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNG 203

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768021900  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642  204 QRHGQGTYTYADGDRYEGEFKNGKRHGQGTLTYAD-GDRYEGEFKNGKRHGQGTMTYADgSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 20-148 8.27e-25

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 103.76  E-value: 8.27e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  20 YEGGRNEaGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLR 99
Cdd:PLN03185  34 YEGEWRR-GMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQ 112

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 768021900 100 HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEG 148
Cdd:PLN03185 113 EGPGKYTWANGNVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHG 160
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
88-109 9.22e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.48  E-value: 9.22e-05
                           10        20
                   ....*....|....*....|..
gi 768021900    88 SRYEGEWANDLRHGHGVYYYIN 109
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 90-112 3.17e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|...
gi 768021900   90 YEGEWANDLRHGHGVYYYINNDT 112
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-165 1.71e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 128.54  E-value: 1.71e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642  124 GGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNG 203

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768021900  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642  204 QRHGQGTYTYADGDRYEGEFKNGKRHGQGTLTYAD-GDRYEGEFKNGKRHGQGTMTYADgSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-143 3.65e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 127.38  E-value: 3.65e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  16 DIGEYEGGRnEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWA 95
Cdd:COG4642  146 NGDVYEGEF-KNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYADGDRYEGEFK 224

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 768021900  96 NDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVN 143
Cdd:COG4642  225 NGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA-DGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
15-165 9.96e-35

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 126.61  E-value: 9.96e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  15 NDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEW 94
Cdd:COG4642   98 FGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADGDRYEGEF 177

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768021900  95 ANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642  178 KNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTYAD-GDRYEGEFKNGKRHGQGTLTYADgDRYEGEFKN 248
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
18-165 7.23e-25

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.42  E-value: 7.23e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:COG4642   78 GGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNG 157

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 768021900  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLN 165
Cdd:COG4642  158 KPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYA-NGDVYEGEFKNGQRHGQGTYTYADgDRYEGEFKN 225
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 20-148 8.27e-25

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 103.76  E-value: 8.27e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  20 YEGGRNEaGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLR 99
Cdd:PLN03185  34 YEGEWRR-GMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQ 112

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 768021900 100 HGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEG 148
Cdd:PLN03185 113 EGPGKYTWANGNVYLGDMKGGKMSGKGTLTWV-SGDSYEGQWLDGMMHG 160
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 34-148 1.41e-22

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 97.21  E-value: 1.41e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  34 GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTY 113
Cdd:PLN03185   1 GELVLSNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTY 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 768021900 114 TGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEG 148
Cdd:PLN03185  81 KGRWRLNLKHGLGYQRYP-NGDVFEGSWIQGLQEG 114
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 18-170 3.93e-22

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 96.06  E-value: 3.93e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  18 GEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWAND 97
Cdd:PLN03185   8 GDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLN 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768021900  98 LRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAeTGSKYVGTWVNGQQEGTAELIHLN-HRYQGKFLNKNERG 170
Cdd:PLN03185  88 LKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWA-NGNVYLGDMKGGKMSGKGTLTWVSgDSYEGQWLDGMMHG 160
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 23-128 1.12e-19

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 88.74  E-value: 1.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  23 GRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGH 102
Cdd:PLN03185  82 GRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGF 161

                         90       100
                 ....*....|....*....|....*.
gi 768021900 103 GVYYYINNDTYTGEWFAHQRHGQGTY 128
Cdd:PLN03185 162 GVYTWSDGGCYVGTWTRGLKDGKGVF 187
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-165 7.55e-16

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 75.38  E-value: 7.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  16 DIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV------------RNKKHGQGTFI 83
Cdd:COG4642   41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGfgggggggggkkGGGGGGGGVLE 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  84 YPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGK 162
Cdd:COG4642  121 GDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLTYAD-GDRYEGEFKNGKRHGQGTLTYANgDVYEGE 199


                 ...
gi 768021900 163 FLN 165
Cdd:COG4642  200 FKN 202
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
16-165 6.64e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 55.35  E-value: 6.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  16 DIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWA 95
Cdd:COG4642   18 LGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  96 NDLRH------------GHGVYYYINNDTYTGEWFAHQRHGQGTYLYAEtGSKYVGTWVNGQQEGTAELIHLN-HRYQGK 162
Cdd:COG4642   98 FGGGGgggggkkgggggGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPN-GDVYEGEFKNGKPHGQGTLTYADgDRYEGE 176


                 ...
gi 768021900 163 FLN 165
Cdd:COG4642  177 FKN 179
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
15-109 1.23e-06

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 47.37  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  15 NDIGEYEGGRNEAGERHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGS-RYE 91
Cdd:COG2849   51 IKKKLGKGLGKYKKGKLGEWKTYYPNGQlKSEGTYKNGKLEGEWKEYYENGKlKSEGNYKNGKLHGEWKEYYENGKlKEE 130

                         90
                 ....*....|....*...
gi 768021900  92 GEWANDLRHGHGVYYYIN 109
Cdd:COG2849  131 GNYKNGKKDGVWKYYDEN 148
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
88-109 9.22e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.48  E-value: 9.22e-05
                           10        20
                   ....*....|....*....|..
gi 768021900    88 SRYEGEWANDLRHGHGVYYYIN 109
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
28-149 2.32e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 40.82  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768021900  28 GERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGS-RYEGEWANDLRHGHGVYY 106
Cdd:COG2849   18 LKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGQlKSEGTYKNGKLEGEWKEY 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 768021900 107 YIN-NDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGT 149
Cdd:COG2849   98 YENgKLKSEGNYKNGKLHGEWKEYYENGKLKEEGNYKNGKKDGV 141
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 90-112 3.17e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 3.17e-04
                          10        20
                  ....*....|....*....|...
gi 768021900   90 YEGEWANDLRHGHGVYYYINNDT 112
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 67-89 4.21e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.00  E-value: 4.21e-04
                          10        20
                  ....*....|....*....|...
gi 768021900   67 YIGEYVRNKKHGQGTFIYPDGSR 89
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
65-86 6.06e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.16  E-value: 6.06e-04
                           10        20
                   ....*....|....*....|..
gi 768021900    65 ARYIGEYVRNKKHGQGTFIYPD 86
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
111-131 1.39e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 35.39  E-value: 1.39e-03
                           10        20
                   ....*....|....*....|.
gi 768021900   111 DTYTGEWFAHQRHGQGTYLYA 131
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYA 21
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
28-100 3.09e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 37.74  E-value: 3.09e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768021900  28 GERHGRGRARLPNGD-TYEGSYEFGKRHGQGIYKFKNGA-RYIGEYVRNKKHGQGTFIYPDGSR-YEGEWANDLRH 100
Cdd:COG2849   88 GKLEGEWKEYYENGKlKSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKDGVWKYYDENGKLvKEEEYKNGKKV 163
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
42-63 4.35e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 33.85  E-value: 4.35e-03
                           10        20
                   ....*....|....*....|..
gi 768021900    42 DTYEGSYEFGKRHGQGIYKFKN 63
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 44-66 7.31e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 33.15  E-value: 7.31e-03
                          10        20
                  ....*....|....*....|...
gi 768021900   44 YEGSYEFGKRHGQGIYKFKNGAR 66
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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