NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|768023323|ref|XP_011528167|]
View 

transport and Golgi organization protein 2 homolog isoform X6 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
 24-156 3.08e-62

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


:

Pssm-ID: 461729  Cd Length: 255  Bit Score: 192.47  E-value: 3.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023323   24 RLILAANRDEFYSRPSKLADFWGNNNEILSGLDMeEGKEGGTWLGISTRGKLAALTNYLQPQLD----WQARGRGELVTH 99
Cdd:pfam05742  15 PLILAANRDEFLNRPTAPAHWWEENPNILGGRDL-EGREGGTWLGITKQGRIAALTNYREPSSGppdaVGARSRGLLVND 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768023323  100 FLTTDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGdvICYYGNRGEPDPIVLTPG 156
Cdd:pfam05742  94 FLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPG 148
 
Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
 24-156 3.08e-62

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


Pssm-ID: 461729  Cd Length: 255  Bit Score: 192.47  E-value: 3.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023323   24 RLILAANRDEFYSRPSKLADFWGNNNEILSGLDMeEGKEGGTWLGISTRGKLAALTNYLQPQLD----WQARGRGELVTH 99
Cdd:pfam05742  15 PLILAANRDEFLNRPTAPAHWWEENPNILGGRDL-EGREGGTWLGITKQGRIAALTNYREPSSGppdaVGARSRGLLVND 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768023323  100 FLTTDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGdvICYYGNRGEPDPIVLTPG 156
Cdd:pfam05742  94 FLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPG 148
Tango2 COG3332
Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, ...
 24-156 7.86e-43

Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, contains NRDE motif [General function prediction only];


Pssm-ID: 442561  Cd Length: 257  Bit Score: 143.09  E-value: 7.86e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023323  24 RLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEegkEGGTWLGISTRGKLAALTNYLQPQL-DWQARGRGELVTHFLT 102
Cdd:COG3332   15 PLVLAANRDEFYARPTAPPARWPDAPGVLAGRDLE---AGGTWLGVNRHGRFAALTNRRDPSGpPAGARSRGELVLDFLA 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 768023323 103 TDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAkgdviCYYGNRGEPDPIVLTPG 156
Cdd:COG3332   92 GESAPAAYLALLALDAAAYNGFNLLVGDADRL-----FYLSNRGDALVRRLAPG 140
 
Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
 24-156 3.08e-62

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


Pssm-ID: 461729  Cd Length: 255  Bit Score: 192.47  E-value: 3.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023323   24 RLILAANRDEFYSRPSKLADFWGNNNEILSGLDMeEGKEGGTWLGISTRGKLAALTNYLQPQLD----WQARGRGELVTH 99
Cdd:pfam05742  15 PLILAANRDEFLNRPTAPAHWWEENPNILGGRDL-EGREGGTWLGITKQGRIAALTNYREPSSGppdaVGARSRGLLVND 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 768023323  100 FLTTDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAKGdvICYYGNRGEPDPIVLTPG 156
Cdd:pfam05742  94 FLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPG 148
Tango2 COG3332
Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, ...
 24-156 7.86e-43

Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, contains NRDE motif [General function prediction only];


Pssm-ID: 442561  Cd Length: 257  Bit Score: 143.09  E-value: 7.86e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023323  24 RLILAANRDEFYSRPSKLADFWGNNNEILSGLDMEegkEGGTWLGISTRGKLAALTNYLQPQL-DWQARGRGELVTHFLT 102
Cdd:COG3332   15 PLVLAANRDEFYARPTAPPARWPDAPGVLAGRDLE---AGGTWLGVNRHGRFAALTNRRDPSGpPAGARSRGELVLDFLA 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 768023323 103 TDVDSLSYLKKVSMEGHLYNGFNLIAADLSTAkgdviCYYGNRGEPDPIVLTPG 156
Cdd:COG3332   92 GESAPAAYLALLALDAAAYNGFNLLVGDADRL-----FYLSNRGDALVRRLAPG 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH