vertnin isoform X1 [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
OTU_VRTN | cd22791 | OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU ... |
74-241 | 6.82e-54 | ||||
OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU domain-containing protein that is required for the development of thoracic vertebrae in mammals. OTU domains typically function as deubiquitinases (DUBs)/ubiquitin thiolesterases (EC 3.4.19.12) that catalyze the thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin, a small regulatory protein that can be conjugated to a large range of target proteins. Protein ubiquitination is a post-translational modification of mostly Lys residues that regulates many cellular processes, including protein degradation, intracellular trafficking, cell signaling, autophagy, transcription, translation, and the DNA damage response. These DUBs may play important regulatory roles at the level of protein turnover by preventing degradation. Vertnin and some subfamily members do not possess the conserved catalytic residues and may not have DUB activity. VRTN gene is associated with variations in vertebral number. : Pssm-ID: 438612 Cd Length: 137 Bit Score: 181.26 E-value: 6.82e-54
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transpos_IS481 super family | cl41329 | IS481 family transposase; null |
271-305 | 9.40e-03 | ||||
IS481 family transposase; null The actual alignment was detected with superfamily member NF033577: Pssm-ID: 411202 [Multi-domain] Cd Length: 283 Bit Score: 38.73 E-value: 9.40e-03
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Name | Accession | Description | Interval | E-value | ||||
OTU_VRTN | cd22791 | OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU ... |
74-241 | 6.82e-54 | ||||
OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU domain-containing protein that is required for the development of thoracic vertebrae in mammals. OTU domains typically function as deubiquitinases (DUBs)/ubiquitin thiolesterases (EC 3.4.19.12) that catalyze the thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin, a small regulatory protein that can be conjugated to a large range of target proteins. Protein ubiquitination is a post-translational modification of mostly Lys residues that regulates many cellular processes, including protein degradation, intracellular trafficking, cell signaling, autophagy, transcription, translation, and the DNA damage response. These DUBs may play important regulatory roles at the level of protein turnover by preventing degradation. Vertnin and some subfamily members do not possess the conserved catalytic residues and may not have DUB activity. VRTN gene is associated with variations in vertebral number. Pssm-ID: 438612 Cd Length: 137 Bit Score: 181.26 E-value: 6.82e-54
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transpos_IS481 | NF033577 | IS481 family transposase; null |
271-305 | 9.40e-03 | ||||
IS481 family transposase; null Pssm-ID: 411202 [Multi-domain] Cd Length: 283 Bit Score: 38.73 E-value: 9.40e-03
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Name | Accession | Description | Interval | E-value | ||||
OTU_VRTN | cd22791 | OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU ... |
74-241 | 6.82e-54 | ||||
OTU (ovarian tumor) domain of vertnin and similar proteins; Vertnin (VRTN) is an OTU domain-containing protein that is required for the development of thoracic vertebrae in mammals. OTU domains typically function as deubiquitinases (DUBs)/ubiquitin thiolesterases (EC 3.4.19.12) that catalyze the thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin, a small regulatory protein that can be conjugated to a large range of target proteins. Protein ubiquitination is a post-translational modification of mostly Lys residues that regulates many cellular processes, including protein degradation, intracellular trafficking, cell signaling, autophagy, transcription, translation, and the DNA damage response. These DUBs may play important regulatory roles at the level of protein turnover by preventing degradation. Vertnin and some subfamily members do not possess the conserved catalytic residues and may not have DUB activity. VRTN gene is associated with variations in vertebral number. Pssm-ID: 438612 Cd Length: 137 Bit Score: 181.26 E-value: 6.82e-54
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OTU | cd22744 | OTU (ovarian tumor) domain family; The OTU family of cysteine proteases use a conserved ... |
79-231 | 1.71e-09 | ||||
OTU (ovarian tumor) domain family; The OTU family of cysteine proteases use a conserved cysteine and histidine, and in most cases an aspartate, as the catalytic triad. OTU domains typically function as deubiquitinases (DUBs)/ubiquitin thiolesterases (EC 3.4.19.12) that catalyze the thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin, a small regulatory protein that can be conjugated to a large range of target proteins. Protein ubiquitination is a post-translational modification of mostly Lys residues that regulates many cellular processes, including protein degradation, intracellular trafficking, cell signaling, autophagy, transcription, translation, and the DNA damage response. These DUBs may play important regulatory roles at the level of protein turnover by preventing degradation. Pssm-ID: 438581 [Multi-domain] Cd Length: 128 Bit Score: 56.29 E-value: 1.71e-09
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transpos_IS481 | NF033577 | IS481 family transposase; null |
271-305 | 9.40e-03 | ||||
IS481 family transposase; null Pssm-ID: 411202 [Multi-domain] Cd Length: 283 Bit Score: 38.73 E-value: 9.40e-03
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Blast search parameters | ||||
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