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Conserved domains on  [gi|767973541|ref|XP_011536358|]
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nuclear envelope integral membrane protein 1 isoform X1 [Homo sapiens]

Protein Classification

nuclear envelope integral membrane protein( domain architecture ID 10562949)

nuclear envelope integral membrane protein similar to Nemp1, which is a RanGTP-binding protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NEMP pfam10225
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
202-446 1.58e-117

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


:

Pssm-ID: 463008  Cd Length: 249  Bit Score: 345.35  E-value: 1.58e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQ 281
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPKKSTFYLLLYGGWGVSLYLLQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  282 LVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTK 361
Cdd:pfam10225  84 QLSENLRSILVEYRIYVLGYVLIVGLISFAVCYRHGPVTDERSINLLKWTLQLLGLVLIYQSSQDPEAAFAILIALLCSK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  362 NLehPIQWLYITCRKVCKGAEKPV---PPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFV 438
Cdd:pfam10225 164 NY--PLSLLSYLRRKWKRRKWFPWkppKRRLLTEEEYREQGEIETRKALEELREYCNSPDCSSWKTVSRLQDPKRFATFV 241

                  ....*...
gi 767973541  439 EGSSHLTP 446
Cdd:pfam10225 242 EGGSHLTP 249
 
Name Accession Description Interval E-value
NEMP pfam10225
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
202-446 1.58e-117

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


Pssm-ID: 463008  Cd Length: 249  Bit Score: 345.35  E-value: 1.58e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQ 281
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPKKSTFYLLLYGGWGVSLYLLQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  282 LVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTK 361
Cdd:pfam10225  84 QLSENLRSILVEYRIYVLGYVLIVGLISFAVCYRHGPVTDERSINLLKWTLQLLGLVLIYQSSQDPEAAFAILIALLCSK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  362 NLehPIQWLYITCRKVCKGAEKPV---PPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFV 438
Cdd:pfam10225 164 NY--PLSLLSYLRRKWKRRKWFPWkppKRRLLTEEEYREQGEIETRKALEELREYCNSPDCSSWKTVSRLQDPKRFATFV 241

                  ....*...
gi 767973541  439 EGSSHLTP 446
Cdd:pfam10225 242 EGGSHLTP 249
EcfT COG0619
ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];
204-312 4.25e-03

ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];


Pssm-ID: 440384  Cd Length: 249  Bit Score: 38.71  E-value: 4.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541 204 IRRFDP--KLFLVFLLGLMLFFCGDLLsrsqifyystgmTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQ 281
Cdd:COG0619   14 LHRLDPrtKLLLLLLLIIAAFLLPSPL------------VLLVLLLLALLLLLLAGIPLRRLLKRLLPLLPFLLLLLLLL 81
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 767973541 282 LVFKNLQEIWRCYWQYL----LSYVLTVGFMSFAV 312
Cdd:COG0619   82 PLFVPGTVLFSLGPLTItregLLLALLLALRLLAL 116
 
Name Accession Description Interval E-value
NEMP pfam10225
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
202-446 1.58e-117

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


Pssm-ID: 463008  Cd Length: 249  Bit Score: 345.35  E-value: 1.58e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQ 281
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPKKSTFYLLLYGGWGVSLYLLQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  282 LVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTK 361
Cdd:pfam10225  84 QLSENLRSILVEYRIYVLGYVLIVGLISFAVCYRHGPVTDERSINLLKWTLQLLGLVLIYQSSQDPEAAFAILIALLCSK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541  362 NLehPIQWLYITCRKVCKGAEKPV---PPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFV 438
Cdd:pfam10225 164 NY--PLSLLSYLRRKWKRRKWFPWkppKRRLLTEEEYREQGEIETRKALEELREYCNSPDCSSWKTVSRLQDPKRFATFV 241

                  ....*...
gi 767973541  439 EGSSHLTP 446
Cdd:pfam10225 242 EGGSHLTP 249
EcfT COG0619
ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];
204-312 4.25e-03

ECF-type transporter transmembrane protein EcfT [Coenzyme transport and metabolism];


Pssm-ID: 440384  Cd Length: 249  Bit Score: 38.71  E-value: 4.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973541 204 IRRFDP--KLFLVFLLGLMLFFCGDLLsrsqifyystgmTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQ 281
Cdd:COG0619   14 LHRLDPrtKLLLLLLLIIAAFLLPSPL------------VLLVLLLLALLLLLLAGIPLRRLLKRLLPLLPFLLLLLLLL 81
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 767973541 282 LVFKNLQEIWRCYWQYL----LSYVLTVGFMSFAV 312
Cdd:COG0619   82 PLFVPGTVLFSLGPLTItregLLLALLLALRLLAL 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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