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Conserved domains on  [gi|767962380|ref|XP_011537894|]
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probable E3 ubiquitin-protein ligase HERC4 isoform X1 [Homo sapiens]

Protein Classification

E3 ubiquitin-protein ligase HERC family protein( domain architecture ID 18804227)

E3 ubiquitin-protein ligase HERC (HECT and RCC1 domain) family protein similar to human E3 ISG15--protein ligase HERC5, the major E3 ligase for ISG15 conjugation, that functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 733-1079 6.51e-146

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


:

Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 440.46  E-value: 6.51e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  733 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 811
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  812 TFEDSD---LFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 888
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  889 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 967
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  968 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1045
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 767962380 1046 SHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFS 1079
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-362 1.82e-82

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 271.85  E-value: 1.82e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkrVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLvGSEECIRVPscfpkimcvdslVRICSGLSygrirnikslsd 160
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTP------------VQVDAGLS------------ 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  161 iQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDcKKQTSPQLLKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGR 240
Cdd:COG5184   150 -GVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGS 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  241 NKFGQLGLNDENDRYVPNLLKSLrsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiV 320
Cdd:COG5184   226 NSSGQLGDGTTTDRATPVQVAGL--TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--V 301

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 767962380  321 TEIACGRQHTSAfVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 362
Cdd:COG5184   302 VAVAAGSSHTCA-LLTDGTVWCWGDNAYGQLGDGTTTDRSTP 342
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 733-1079 6.51e-146

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 440.46  E-value: 6.51e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  733 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 811
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  812 TFEDSD---LFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 888
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  889 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 967
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  968 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1045
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 767962380 1046 SHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFS 1079
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 759-1078 3.25e-112

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 351.15  E-value: 3.25e-112
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    759 KKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSD----LFHLIGVICGLAIYNCT 834
Cdd:smart00119    4 KRVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSGFANEehlsYFRFIGRVLGKALYDNR 83

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    835 IVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQL-LDYPEDDIEEtfcLNFTITVEN-FGATEVKELVLNGADTAV 912
Cdd:smart00119   84 LLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLlLNNDTSEELD---LTFSIVLTSeFGQVKVVELKPGGSNIPV 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    913 NKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPT 992
Cdd:smart00119  161 TEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQT 240

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    993 IKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQ 1070
Cdd:smart00119  241 IKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALspKFTIRKAGSDDERLPTAHTCFNRLKLPPYSSKEILREKLLL 320


                    ....*...
gi 767962380   1071 AIDHNEGF 1078
Cdd:smart00119  321 AINEGKGF 328
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 783-1081 4.34e-104

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 328.80  E-value: 4.34e-104
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   783 LLIMRELLDPKYGMFRY-YEDSRLIWFSDKTFED-----SDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLD 856
Cdd:pfam00632    1 TLLSKELFDPNYGLFEYeTEDDRTYWFNPSSSESpdlelLDYFKFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   857 DLKELMPDVGRSMQQLLDYpEDDIEETFCLNFTITVenFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASL 936
Cdd:pfam00632   81 DLESIDPELYKSLKSLLNM-DNDDDEDLGLTFTIPV--FGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQ 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   937 FDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLT 1016
Cdd:pfam00632  158 LEAFRKGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVT 237

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767962380  1017 GSDRIPILGMKSL-KLVIQSTGG-GEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI 1081
Cdd:pfam00632  238 GSSRLPVGGFKSLpKFTIVRKGGdDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGFGLS 304
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
684-1081 3.50e-91

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 311.70  E-value: 3.50e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  684 TYPFVFDAQAKTTLLQTD-----AVLQMQMAIDQ---AHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKN 755
Cdd:COG5021   458 LYRFYFVEHRKKTLTKNDsrlgsFISLNKLDIRRikeDKRRKLFYSLKQKAKIFDPYLHIKVRRDRVFEDSYREIMDESG 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  756 IDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIW----FSDKTFEDSDLFHLIGVICGLAIY 831
Cdd:COG5021   538 DDLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLpinpLSSINPEHLSYFKFLGRVIGKAIY 617

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  832 NCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNFTITVENFGATEVKELVLNGADTA 911
Cdd:COG5021   618 DSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDID--ETILDLTFTVEDDSFGESRTVELIPNGRNIS 695

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  912 VNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG-NTNYDWKELEKNTEYKGeYWAEH 990
Cdd:COG5021   696 VTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAYHG-YTEDS 774

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  991 PTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL-------KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKET 1063
Cdd:COG5021   775 PIIVWFWEIISEFDFEERAKLLQFVTGTSRIPINGFKDLqgsdgvrKFTIEKGGTDDDRLPSAHTCFNRLKLPEYSSKEK 854

                         410
                  ....*....|....*...
gi 767962380 1064 LRSKLIQAIDHNEGFSLI 1081
Cdd:COG5021   855 LRSKLLTAINEGAGFGLL 872
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-362 1.82e-82

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 271.85  E-value: 1.82e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkrVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLvGSEECIRVPscfpkimcvdslVRICSGLSygrirnikslsd 160
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTP------------VQVDAGLS------------ 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  161 iQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDcKKQTSPQLLKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGR 240
Cdd:COG5184   150 -GVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGS 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  241 NKFGQLGLNDENDRYVPNLLKSLrsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiV 320
Cdd:COG5184   226 NSSGQLGDGTTTDRATPVQVAGL--TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--V 301

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 767962380  321 TEIACGRQHTSAfVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 362
Cdd:COG5184   302 VAVAAGSSHTCA-LLTDGTVWCWGDNAYGQLGDGTTTDRSTP 342
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
232-281 5.08e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 72.94  E-value: 5.08e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 767962380   232 SGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 281
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
HECTc cd00078
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
 733-1079 6.51e-146

HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.


Pssm-ID: 238033 [Multi-domain]  Cd Length: 352  Bit Score: 440.46  E-value: 6.51e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  733 LILVVRRENIVGDAMEVLRKTKNIDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDS-RLIWFSDK 811
Cdd:cd00078     1 LKITVRRDRILEDALRQLSKVSSSDLKKVLEVEFVGEEGIDAGGVTREFFTLVSKELFNPSYGLFRYTPDDsGLLYPNPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  812 TFEDSD---LFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNF 888
Cdd:cd00078    81 SFADEDhlkLFRFLGRLLGKALYEGRLLDLPFSRAFYKKLLGKPLSLEDLEELDPELYKSLKELLDNDGD--EDDLELTF 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  889 TITVEN-FGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG 967
Cdd:cd00078   159 TIELDSsFGGAVTVELKPGGRDIPVTNENKEEYVDLYVDYRLNKGIEEQVEAFRDGFSEVIPEELLSLFTPEELELLICG 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  968 NTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPV 1045
Cdd:cd00078   239 SEDIDLEDLKKNTEYKGGYSSDSPTIQWFWEVLESFTNEERKKFLQFVTGSSRLPVGGFADLnpKFTIRRVGSPDDRLPT 318

                         330       340       350
                  ....*....|....*....|....*....|....
gi 767962380 1046 SHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFS 1079
Cdd:cd00078   319 AHTCFNLLKLPPYSSKEILREKLLYAINEGAGFG 352
HECTc smart00119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
 759-1078 3.25e-112

Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.


Pssm-ID: 214523  Cd Length: 328  Bit Score: 351.15  E-value: 3.25e-112
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    759 KKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTFEDSD----LFHLIGVICGLAIYNCT 834
Cdd:smart00119    4 KRVLEIEFEGEEGLDGGGVTREFFFLLSKELFNPDYGLFRYSPNDYLLYPNPRSGFANEehlsYFRFIGRVLGKALYDNR 83

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    835 IVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQL-LDYPEDDIEEtfcLNFTITVEN-FGATEVKELVLNGADTAV 912
Cdd:smart00119   84 LLDLFFARPFYKKLLGKPVTLHDLESLDPELYKSLKWLlLNNDTSEELD---LTFSIVLTSeFGQVKVVELKPGGSNIPV 160

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    913 NKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPT 992
Cdd:smart00119  161 TEENKKEYVHLVIEYRLNKGIEKQLEAFREGFSEVIPENLLKLFDPEELELLICGSPEIDVDDLKSNTEYKGGYSANSQT 240

                           250       260       270       280       290       300       310       320
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    993 IKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL--KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQ 1070
Cdd:smart00119  241 IKWFWEVVESFTNEERRKLLQFVTGSSRLPVGGFAALspKFTIRKAGSDDERLPTAHTCFNRLKLPPYSSKEILREKLLL 320


                    ....*...
gi 767962380   1071 AIDHNEGF 1078
Cdd:smart00119  321 AINEGKGF 328
HECT pfam00632
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
 783-1081 4.34e-104

HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.


Pssm-ID: 459880  Cd Length: 304  Bit Score: 328.80  E-value: 4.34e-104
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   783 LLIMRELLDPKYGMFRY-YEDSRLIWFSDKTFED-----SDLFHLIGVICGLAIYNCTIVDLHFPLALYKKLLKKKPSLD 856
Cdd:pfam00632    1 TLLSKELFDPNYGLFEYeTEDDRTYWFNPSSSESpdlelLDYFKFLGKLLGKAIYNGILLDLPFPPFFYKKLLGEPLTLE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   857 DLKELMPDVGRSMQQLLDYpEDDIEETFCLNFTITVenFGATEVKELVLNGADTAVNKQNRQEFVDAYVDYIFNKSVASL 936
Cdd:pfam00632   81 DLESIDPELYKSLKSLLNM-DNDDDEDLGLTFTIPV--FGESKTIELIPNGRNIPVTNENKEEYIRLYVDYRLNKSIEPQ 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   937 FDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKKQFLLFLT 1016
Cdd:pfam00632  158 LEAFRKGFYSVIPKEALSLFTPEELELLICGSPEIDVEDLKKNTEYDGGYTKNSPTIQWFWEILEEFSPEQRRLFLKFVT 237

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767962380  1017 GSDRIPILGMKSL-KLVIQSTGG-GEEYLPVSHTCFNLLDLPKYTEKETLRSKLIQAIDHNEGFSLI 1081
Cdd:pfam00632  238 GSSRLPVGGFKSLpKFTIVRKGGdDDDRLPTAHTCFNRLKLPDYSSKEILKEKLLIAIEEGEGFGLS 304
HUL4 COG5021
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
684-1081 3.50e-91

Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227354 [Multi-domain]  Cd Length: 872  Bit Score: 311.70  E-value: 3.50e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  684 TYPFVFDAQAKTTLLQTD-----AVLQMQMAIDQ---AHRQNVSSLFLPVIESVNPCLILVVRRENIVGDAMEVLRKTKN 755
Cdd:COG5021   458 LYRFYFVEHRKKTLTKNDsrlgsFISLNKLDIRRikeDKRRKLFYSLKQKAKIFDPYLHIKVRRDRVFEDSYREIMDESG 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  756 IDYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIW----FSDKTFEDSDLFHLIGVICGLAIY 831
Cdd:COG5021   538 DDLKKTLEIEFVGEEGIDAGGLTREWLFLLSKEMFNPDYGLFEYITEDLYTLpinpLSSINPEHLSYFKFLGRVIGKAIY 617

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  832 NCTIVDLHFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDdiEETFCLNFTITVENFGATEVKELVLNGADTA 911
Cdd:COG5021   618 DSRILDVQFSKAFYKKLLGKPVSLVDLESLDPELYRSLVWLLNNDID--ETILDLTFTVEDDSFGESRTVELIPNGRNIS 695

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  912 VNKQNRQEFVDAYVDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIG-NTNYDWKELEKNTEYKGeYWAEH 990
Cdd:COG5021   696 VTNENKKEYVKKVVDYKLNKRVEKQFSAFKSGFSEIIPPDLLQIFDESELELLIGGiPEDIDIDDWKSNTAYHG-YTEDS 774

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  991 PTIKIFWEVFHELPLEKKKQFLLFLTGSDRIPILGMKSL-------KLVIQSTGGGEEYLPVSHTCFNLLDLPKYTEKET 1063
Cdd:COG5021   775 PIIVWFWEIISEFDFEERAKLLQFVTGTSRIPINGFKDLqgsdgvrKFTIEKGGTDDDRLPSAHTCFNRLKLPEYSSKEK 854

                         410
                  ....*....|....*...
gi 767962380 1064 LRSKLIQAIDHNEGFSLI 1081
Cdd:COG5021   855 LRSKLLTAINEGAGFGLL 872
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 3-362 1.82e-82

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 271.85  E-value: 1.82e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINkrVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVA 80
Cdd:COG5184    21 CWGDNSYGQLGDG--TTTDRSTPVRVPGLSN--VVAVAAGGDHTCALKADGTVWCWGNNSYGQLGdgTTTDRTTPVKVPG 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   81 LDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLvGSEECIRVPscfpkimcvdslVRICSGLSygrirnikslsd 160
Cdd:COG5184    97 LT--GVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTP------------VQVDAGLS------------ 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  161 iQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDcKKQTSPQLLKSLLGIpfMQVAAGGAHSFVLTLSGAIFGWGR 240
Cdd:COG5184   150 -GVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTT-TDRPTPVQVGGLSGV--VAVAAGGDHSCALKSDGTVWCWGS 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  241 NKFGQLGLNDENDRYVPNLLKSLrsQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiV 320
Cdd:COG5184   226 NSSGQLGDGTTTDRATPVQVAGL--TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--V 301

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 767962380  321 TEIACGRQHTSAfVPSSGRIYSFGLGGNGQLGTGSTSNRKSP 362
Cdd:COG5184   302 VAVAAGSSHTCA-LLTDGTVWCWGDNAYGQLGDGTTTDRSTP 342
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 37-367 4.69e-76

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 254.13  E-value: 4.69e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   37 RDVGCGLRHTVFVLDDGTVYTCGCNDLGQLG--HEKSRKKPEQVVALDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDG 114
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGdgTTTDRSTPVRVPGLS--NVVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  115 QLGLvGSEECIRVPscfpkimcvdslVRIcSGLSYgrirnikslsdiqIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 194
Cdd:COG5184    79 QLGD-GTTTDRTTP------------VKV-PGLTG-------------VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLG 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  195 LGTDcKKQTSPQLLKSLLGiPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSqkIVYICCG 274
Cdd:COG5184   132 DGTT-TNRLTPVQVDAGLS-GVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG--VVAVAAG 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380  275 EDHTAALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGsiVTEIACGRQHTSAfVPSSGRIYSFGLGGNGQLGTG 354
Cdd:COG5184   208 GDHSCALKSDGTVWCWGSNSSGQLGDGTTTDRATPVQVAGLTG--VVAIAAGGSHTCA-LKSDGTVWCWGDNSYGQLGDG 284

                         330
                  ....*....|...
gi 767962380  355 STSNRKSPFTVKG 367
Cdd:COG5184   285 TTTDRSTPVKVPG 297
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 1-206 3.94e-38

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 146.28  E-value: 3.94e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380    1 MLCWGNASFGQLGLGGIDEEIVlePRKSDFFINkrVRDVGCGLRHTVFVLDDGTVYTCGCNDLGQLGHE--KSRKKPEQV 78
Cdd:COG5184   170 VWCWGANSYGQLGDGTTTDRPT--PVQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLGDGttTDRATPVQV 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767962380   79 VALDaqNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLvGSEECIRVPscfpkimcvdslVRIcSGLSygrirniksl 158
Cdd:COG5184   246 AGLT--GVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGD-GTTTDRSTP------------VKV-PGLS---------- 299

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 767962380  159 sdiQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDcKKQTSPQ 206
Cdd:COG5184   300 ---GVVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTT-TDRSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
232-281 5.08e-16

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 72.94  E-value: 5.08e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 767962380   232 SGAIFGWGRNKFGQLGLNDENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 281
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
52-99 2.78e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 65.23  E-value: 2.78e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 767962380    52 DGTVYTCGCNDLGQLGH--EKSRKKPEQVVALDAQNIVAVSCGEAHTLAL 99
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLgtTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
181-229 4.48e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 64.46  E-value: 4.48e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 767962380   181 EVFCWGQNKYGQLGLGTDcKKQTSPQLLKSLLGIPFMQVAAGGAHSFVL 229
Cdd:pfam00415    3 RVYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
284-332 2.18e-12

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 62.53  E-value: 2.18e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 767962380   284 EGGVFTFGAGGYGQLGHNSTSHEINPRKVFELMGSIVTEIACGRQHTSA 332
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVA 49
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
102-176 1.06e-10

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 57.91  E-value: 1.06e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767962380   102 KGQVYAWGLDSDGQLGLvGSEECIRVPSCfpkimcvdslvricsglsygrirnIKSLSDIQIVQVACGYYHSLAL 176
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGL-GTTENVLVPQK------------------------VEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
163-192 1.64e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 53.97  E-value: 1.64e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 767962380   163 IVQVACGYYHSLALSKASEVFCWGQNKYGQ 192
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
86-115 3.95e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 49.73  E-value: 3.95e-08
                           10        20        30
                   ....*....|....*....|....*....|
gi 767962380    86 IVAVSCGEAHTLALNDKGQVYAWGLDSDGQ 115
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
36-65 1.32e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 48.57  E-value: 1.32e-07
                           10        20        30
                   ....*....|....*....|....*....|
gi 767962380    36 VRDVGCGLRHTVFVLDDGTVYTCGCNDLGQ 65
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
3-49 1.58e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 48.67  E-value: 1.58e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 767962380     3 CWGNASFGQLGLGgiDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFV 49
Cdd:pfam00415    6 TWGRNDYGQLGLG--TTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
218-245 2.00e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 45.11  E-value: 2.00e-06
                           10        20
                   ....*....|....*....|....*...
gi 767962380   218 QVAAGGAHSFVLTLSGAIFGWGRNKFGQ 245
Cdd:pfam13540    3 SVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
337-367 1.53e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 43.27  E-value: 1.53e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 767962380   337 SGRIYSFGLGGNGQLGTGSTSNRKSPFTVKG 367
Cdd:pfam00415    1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG 31
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
268-297 1.71e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.41  E-value: 1.71e-05
                           10        20        30
                   ....*....|....*....|....*....|
gi 767962380   268 IVYICCGEDHTAALTKEGGVFTFGAGGYGQ 297
Cdd:pfam13540    1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
320-350 3.87e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 35.86  E-value: 3.87e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 767962380   320 VTEIACGRQHTsAFVPSSGRIYSFGLGGNGQ 350
Cdd:pfam13540    1 VVSVAAGDNHT-LALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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