|
Name |
Accession |
Description |
Interval |
E-value |
| mam_aldehyde_ox |
TIGR02969 |
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ... |
11-1336 |
0e+00 |
|
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain] Cd Length: 1330 Bit Score: 1864.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 11 LVFFVNGKKVVEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYQPQTKSILHFSANACLLPICLLTEAAV 90
Cdd:TIGR02969 3 LLFYVNGRKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNPSTKSIRHHPVNACLTPICSLYGAAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 91 TTVEGIGSTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYKTFCG 170
Cdd:TIGR02969 83 TTVEGIGSTRTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALLRNHPEPTLDQLTDALGGNLCRCTGYRPIIDACKTFCK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 171 ASNCCQTNSNGDCCLNEELLG----QDKENVFSELFNKDDLIPLDPTQELIFPPELIIMAEKQERKSLTFRGERITWISP 246
Cdd:TIGR02969 163 TSGCCQSKENGVCCLDQGINGlpefEEGDETSPELFSEEEFLPLDPTQELIFPPELMRMAEKQPQRTRVFYSERMMWISP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 247 VSLEELIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEGVSIGAGCSLSTVIKLLEELVSSL 326
Cdd:TIGR02969 243 VTLKELLEAKFKYPQAPVVMGNTSVGPEVKFKGVFHPVIISPDRIEELSVVNHTGDGLTLGAGLSLAQVKDILADVVQKL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 327 PEEETEIFRALLKQMKNVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILNEDFFVGFGKTALT 406
Cdd:TIGR02969 323 PEETTQTYRALLKHLGTLAGSQIRNMASLGGHIISRHLDSDLNPLLAVGNCTLNLLSKEGKRQIPLSEQFLSKCPDADLK 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 407 PDEILVSVFIPFSKRGEFVRVFRQAPRQENAFCSVNSGMKVQFKEGTAVVEDLSIFYGGVGPCTVKAKKTCQEIIGRPWN 486
Cdd:TIGR02969 403 PQEILVSVNIPYSRKWEFVSAFRQAQRQQNALAIVNSGMRVFFGEGDGIIRELSISYGGVGPTTICAKNSCQKLIGRPWN 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 487 EKTISEAYRLLLDEIELPPSAPGGMVEFRRALTLSFLFKFYLEMLQKLGEMN-VTLEDVPGEFASAIRFFPQKREHSVQE 565
Cdd:TIGR02969 483 EEMLDTACRLILDEVSLAGSAPGGKVEFKRTLIISFLFKFYLEVSQILKRMDpGHYPSLADKYESALEDLHSKHHWSTLK 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 566 FQVVAHDQPCWDPVGHPIMHRSAISQATGEAVYCDDIPKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKD 645
Cdd:TIGR02969 563 HQNVDSMQLPQDPIGHPIMHLSGVKHATGEAIYCDDMPAVDQELFLTFVTSSRAHAKIVSIDLSEALSLPGVVDIITAEH 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 646 IP-GKKFRTftnidEELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLQPLIFTIQEAIEKQSFFKPQRRIEK 724
Cdd:TIGR02969 643 LQdANTFGT-----EKLLATDKVHCVGQLVCAVIADSEVQAKQAAKHVKIVYRDLEPLILTIEEAIQHKSFFEPERKLEY 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 725 GNVEEAFEKADQVLEGEIQIGGQEHFYMETQSMLVIPVQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVKRLGG 804
Cdd:TIGR02969 718 GNVDEAFKVVDQILEGEIHMGGQEHFYMETQSMLVVPKGEDQEMDVYVSTQFPKYIQDIVAATLKLPVNKVMCHVRRVGG 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 805 AFGGKVTRTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGDESIL 884
Cdd:TIGR02969 798 AFGGKVGKTSIMAAITAFAANKHGRAVRCTLERGEDMLITGGRHPYLGKYKAGFMNDGRIVALDVEHYSNGGSSLDESLW 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 885 VIEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGTSCTHYK 964
Cdd:TIGR02969 878 VIEMGLLKMDNAYKFPNLRCRGWACRTNLPSNTAFRGFGFPQAGLITEACITEVAAKCGLSPEKVRTINMYKEIDQTPYK 957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 965 LAFDPHNLWRCWDECLEKSAFSNRRIAINKFNKQNRWKKRGIAVVPIKYGIAFAESFLNQAAALVHIYKDGSVLLSHGGT 1044
Cdd:TIGR02969 958 QEINAKNLFQCWRECMAKSSYSERKVAVEKFNAENYWKKRGLAVIPLKFPVGLGSVAMGQAAALVHIYLDGSVLVTHGGI 1037
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1045 EMGQGIHTKMQQVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRLEPIIHDNPKGTWQDW 1124
Cdd:TIGR02969 1038 EMGQGVHTKMIQVVSRELKMPMSNVHLRGTSTETVPNTNASGGSVVADLNGLAVKDACQTLLKRLEPIISKNPQGTWKDW 1117
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1125 IKTAYFQKISLSSTGFYRGHDLYMDWEKQEGRPYAYFTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINPSVDIGQIE 1204
Cdd:TIGR02969 1118 AQTAFDQSISLSAVGYFRGYESNINWEKGEGHPFEYFVYGAACSEVEIDCLTGDHKNIRTDIVMDVGHSINPALDIGQVE 1197
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1205 GAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVPLTFNVYLLAGSQNPHAIYSSKGIGEPVLFLGSSVFFAIKD 1284
Cdd:TIGR02969 1198 GAFIQGMGLYTIEELSYSPQGILYSRGPNQYKIPAICDIPTELHISFLPPSEHSNTLYSSKGLGESGVFLGCSVFFAIHD 1277
|
1290 1300 1310 1320 1330
....*....|....*....|....*....|....*....|....*....|...
gi 973181399 1285 AVSAARKERDLKGPFRLDSPATAEKICHACSNCFIQMIPATKPGSQ-PWAINV 1336
Cdd:TIGR02969 1278 AVRAARQERGLSGPWKLTSPLTPEKIRMACEDKFTKMIPRDEPGSYvPWNVPV 1330
|
|
| PLN02906 |
PLN02906 |
xanthine dehydrogenase |
28-1318 |
0e+00 |
|
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain] Cd Length: 1319 Bit Score: 1498.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 28 ETTLLSYIREkLRLTGTKYACGGGGCGACTVMVSKYQPQTKSILHFSANACLLPICLLTEAAVTTVEGIGSTKTRIHPVQ 107
Cdd:PLN02906 1 HQTLLEYLRD-LGLTGTKLGCGEGGCGACTVMVSHYDRKTGKCVHYAVNACLAPLYSVEGMHVITVEGIGNRRDGLHPVQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 108 ERIAKAHGSQCGFCTPGMVMSMYTLLRNIPE-PTMEDIQEALGGNLCRCTGYRPILDGYKTFC---------GASNCCQT 177
Cdd:PLN02906 80 EALASMHGSQCGFCTPGFIMSMYALLRSSKTpPTEEQIEECLAGNLCRCTGYRPILDAFRVFAktddalytgVSSLSLQD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 178 N-----SNGDCCLNEELLGQDKENVFSELFNKDDLIPLD----PTQELIFPPELiimaekQERK--SLTFRG-ERITWIS 245
Cdd:PLN02906 160 GepicpSTGKPCSCGSKTTSAAGTCKSDRFQPISYSEIDgswyTEKELIFPPEL------LLRKltPLKLLGnGGLTWYR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 246 PVSLEELIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEGVSIGAGCSLSTVIKLLEELVSS 325
Cdd:PLN02906 234 PTSLQHLLELKAEYPDAKLVVGNTEVGIEMRFKNAQYPVLISPTHVPELNAIKVKDDGLEIGAAVRLSELQNLFRKVVKE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 326 LPEEETEIFRALLKQMKNVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILNEDFFVGFGKTAL 405
Cdd:PLN02906 314 RPAHETSACKAFIEQLKWFAGTQIRNVASIGGNICTASPISDLNPLWMAAGATFVIISCDGDIRSVPASDFFLGYRKVDL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 406 TPDEILVSVFIPFSKRGEFVRVFRQAPRQENAFCSVNSGMKVQFKEGTA--VVEDLSIFYGGVGPCTVKAKKTCQEIIGR 483
Cdd:PLN02906 394 KPDEILLSVFLPWTRPFEYVKEFKQAHRRDDDIAIVNAGMRVKLEEKDGewIVSDASIAYGGVAPLSVSARKTEEFLIGK 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 484 PWNEKTISEAYRLLLDEIELPPSAPGGMVEFRRALTLSFLFKFYLEMLQKLGEMNVTLEDVPGEFASAIRFFPQKREHSV 563
Cdd:PLN02906 474 PWNKETLQDALKVLQKDILIKEDAPGGMVEFRKSLALSFFFKFFLWVSHQLEADGSTIETFPESHLSAAQPFPRPSSVGM 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 564 QEFQVVAHDqpcwDPVGHPIMHRSAISQATGEAVYCDDIPKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITA 643
Cdd:PLN02906 554 QDYETVKQG----TAVGQPEVHLSAELQVTGEAEYADDIPMPPNTLHAALVLSTKPHARILSIDDSEAKSSPGFAGIFLA 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 644 KDIPGKKFRTFTNIDEELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLqPLIFTIQEAIEKQSFF-KPQRRI 722
Cdd:PLN02906 630 KDVPGDNMIGPVVHDEELFATDVVTCVGQVIGVVVADTQENAKAAARKVKVEYEEL-PAILSIEEAIEAGSFHpNTERRL 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 723 EKGNVEEAFE--KADQVLEGEIQIGGQEHFYMETQSMLVIPVQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVK 800
Cdd:PLN02906 709 EKGDVELCFAsgQCDRIIEGEVQMGGQEHFYLEPNSSLVWTSDSGNEVHMISSTQAPQKHQKYVAHVLGLPMSKVVCKTK 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 801 RLGGAFGGKVTRTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGD 880
Cdd:PLN02906 789 RIGGGFGGKETRSAFIAAAAAVPAYLLNRPVKLTLDRDVDMMITGQRHAFLGKYKVGFTNEGKILALDLEIYNNGGNSLD 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 881 ESILVIEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGTSC 960
Cdd:PLN02906 869 LSGAVLERAMFHSDNVYEIPNVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAVELNKSPEEIREMNFQGEGSV 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 961 THYKLAFDPHNLWRCWDECLEKSAFSNRRIAINKFNKQNRWKKRGIAVVPIKYGIAFAESFLNQAAALVHIYKDGSVLLS 1040
Cdd:PLN02906 949 THYGQVLQHCTLPQLWDELKVSCDFLKRREEVDEFNAKNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVT 1028
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1041 HGGTEMGQGIHTKMQQVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRLEPIIHDNPKGT 1120
Cdd:PLN02906 1029 HGGVEMGQGLHTKVAQVAASAFNIPLSSVFISETSTDKVPNASPTAASASSDMYGAAVLDACEQIKARMEPVASKLNFSS 1108
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1121 WQDWIKTAYFQKISLSSTGFYRGHDLYMDWEKQEGRPYAYFTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINPSVDI 1200
Cdd:PLN02906 1109 FAELVTACYFQRIDLSAHGFYITPDIGFDWKTGKGNPFNYFTYGAAFAEVEIDTLTGDFHTRRVDIVMDLGYSINPAIDI 1188
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1201 GQIEGAFIQGLGLYTMEELKFS-------PSGVLYTRGPAQYKIPAVCDVPLTFNVYLLAGSQNPHAIYSSKGIGEPVLF 1273
Cdd:PLN02906 1189 GQIEGAFVQGLGWVALEELKWGdaahkwiRPGSLFTCGPGTYKIPSVNDIPFKFNVSLLKGAPNPKAIHSSKAVGEPPFF 1268
|
1290 1300 1310 1320
....*....|....*....|....*....|....*....|....*
gi 973181399 1274 LGSSVFFAIKDAVSAARKERDLKGPFRLDSPATAEKICHACSNCF 1318
Cdd:PLN02906 1269 LAASVFFAIKDAIKAARAEVGLHGWFPLDTPATPERIRMACGDEI 1313
|
|
| XdhB |
COG4631 |
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and ... |
572-1314 |
0e+00 |
|
Xanthine dehydrogenase, molybdopterin-binding subunit XdhB [Nucleotide transport and metabolism];
Pssm-ID: 443669 [Multi-domain] Cd Length: 769 Bit Score: 957.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 572 DQPCWDPVGHPIMHRSAISQATGEAVYCDDIPKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKf 651
Cdd:COG4631 7 PPPAAGAVGKSLPHESARLHVTGEARYIDDLPEPAGTLHAAPGLSPVAHARILSIDLSAVRAAPGVVAVLTAADIPGEN- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 652 rtftNI-----DEELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLQPlIFTIQEAIEKQSFFKPQRRIEKGN 726
Cdd:COG4631 86 ----DIgpiihDEPLLADGEVEYVGQPVFAVVAESREAARRAARLAKIEYEELPA-ILTIEEALAAGSFVLPPHTLRRGD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 727 VEEAFEKADQVLEGEIQIGGQEHFYMETQSMLVIPvQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVKRLGGAF 806
Cdd:COG4631 161 ADAALAAAPHRLEGEFEIGGQEHFYLEGQIALAIP-GEDGGMLVHSSTQHPSEVQHLVAHVLGVPMHAVTVEVRRMGGGF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 807 GGKVTRTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGDESILVI 886
Cdd:COG4631 240 GGKESQAALFAALAALAARKTGRPVKLRLDRDDDMVMTGKRHPFRIDYEVGFDDDGRILGLDITLAARCGWSADLSGPVA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 887 EKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGTSC--THYK 964
Cdd:COG4631 320 DRAMFHADNAYYLPAVRITGHRCKTNTQSNTAFRGFGGPQGMLAIERVIDDIARALGLDPLDVRRRNFYGPAERntTPYG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 965 LAFDPHNLWRCWDECLEKSAFSNRRIAINKFNKQNRWKKRGIAVVPIKYGIAFAESFLNQAAALVHIYKDGSVLLSHGGT 1044
Cdd:COG4631 400 QPVEDNILHELVDELEESSDYAARRAAIAAFNAASPVLKRGLALTPVKFGISFTATHLNQAGALVHVYTDGSVQLNHGGT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1045 EMGQGIHTKMQQVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRLEP------------- 1111
Cdd:COG4631 480 EMGQGLHTKVAQVVADELGVPLERVRITATDTDKVPNTSATAASSGSDLNGMAAQDACRQIRERLAAfaaellgvepedv 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1112 ------IIHDNPKGTWQDWIKTAYFQKISLSSTGFYRGHDLYMDWEKQEGRPYAYFTYGVSCSEVEIDCLTGDHKNIRAD 1185
Cdd:COG4631 560 rfadgrVRVGGQSLSFAELVKAAYLARVSLSATGFYKTPKIHWDRATGQGRPFYYFAYGAAVSEVEIDTLTGEYRVLRVD 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1186 IVMDTGRSINPSVDIGQIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVPLTFNVYLLAGSQNPHAIYSSK 1265
Cdd:COG4631 640 ILHDVGRSLNPAIDIGQIEGGFVQGMGWLTTEELVWDDKGRLLTHAPSTYKIPAASDRPEDFNVALLERPNREDTIYRSK 719
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 973181399 1266 GIGEPVLFLGSSVFFAIKDAVSAARKERdlkGPFRLDSPATAEKICHAC 1314
Cdd:COG4631 720 AVGEPPLMLGISVFEALRDAVAAVGDYR---VSPPLDAPATPERVLMAV 765
|
|
| xanthine_xdhB |
TIGR02965 |
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the ... |
579-1314 |
0e+00 |
|
xanthine dehydrogenase, molybdopterin binding subunit; Members of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274367 [Multi-domain] Cd Length: 758 Bit Score: 778.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 579 VGHPIMHRSAISQATGEAVYCDDIPKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKFRTFTNID 658
Cdd:TIGR02965 1 VGTSLKHESAHKHVAGTAVYIDDIPEPAGTLHAALGLSTRAHARITSMDLSAVRAAPGVVDVLTAADIPGENDISPIIHD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 659 EELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLqPLIFTIQEAIEKQS-FFKPQRRIEKGNVEEAFEKADQV 737
Cdd:TIGR02965 81 DPLLADGKVEFVGQPIFAVVATSRDAARRAARLAKIEYEEL-PAVLDIEEALAAGSrLVTPPLTLERGDAAAALAAAPHR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 738 LEGEIQIGGQEHFYMETQSMLVIPvQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVKRLGGAFGGKVTRTSVMA 817
Cdd:TIGR02965 160 LSGTMRIGGQEHFYLEGQIALAVP-GEDGGMHVWSSTQHPSEVQHLVAHVLGVPSHAVTVEVRRMGGGFGGKETQANLFA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 818 SITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGDESILVIEKILLHMDNSY 897
Cdd:TIGR02965 239 CLAAVAARKTGRPVKLRPDRDDDMMITGKRHDFRVDYDVGFDDEGRILGVDIDMAARCGFSADLSGPVTDRALFHADNAY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 898 NIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGT--SCTHYKLAFDPHNLWRC 975
Cdd:TIGR02965 319 FLPDVTITSHPLKTNTQSNTAFRGFGGPQGMVAIERIMDEVARALGKDPLEVRKRNFYGKDerNVTPYHQTVEDNIIHEI 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 976 WDECLEKSAFSNRRIAINKFNKQNRWKKRGIAVVPIKYGIAFAESFLNQAAALVHIYKDGSVLLSHGGTEMGQGIHTKMQ 1055
Cdd:TIGR02965 399 IEELEASSDYAARRAAIRAFNATSPVLKKGIALTPVKFGISFTVTHLNQAGALVHVYTDGSIHLNHGGTEMGQGLNTKVA 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1056 QVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRL-----------EPIIHDNPKG----- 1119
Cdd:TIGR02965 479 QVVAEEFQVDIDRVKITATDTGKVPNTSATAASSGSDLNGMAAQDAARQIKERLvefaaekwqvpEEDVRFAPNHvrvge 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1120 ---TWQDWIKTAYFQKISLSSTGFYRGHDLYMDWEKQEGRPYAYFTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINP 1196
Cdd:TIGR02965 559 qrvPFAELVQQAYFARVQLSSTGFYKTPKIHWDRAKGRGRPFYYFAYGAACSEVSVDTLTGEYKVLRADILHDVGRSLNP 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1197 SVDIGQIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVPLTFNVYLLAGSQNP-HAIYSSKGIGEPVLFLG 1275
Cdd:TIGR02965 639 AIDIGQIEGGFVQGMGWLTTEELVWDEKGRLRTHAPSTYKIPAASDRPKDFNVRLFEWGENReDTIHRSKAVGEPPLMLG 718
|
730 740 750
....*....|....*....|....*....|....*....
gi 973181399 1276 SSVFFAIKDAVSAArkeRDLKGPFRLDSPATAEKICHAC 1314
Cdd:TIGR02965 719 ISVLFAISDAVASV---ADYRVCPRLDAPATPERVLMAV 754
|
|
| PLN00192 |
PLN00192 |
aldehyde oxidase |
7-1306 |
0e+00 |
|
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain] Cd Length: 1344 Bit Score: 756.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 7 SSENLVFFVNGKKVVEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYQPQTKSILHFSANACLLPICLLT 86
Cdd:PLN00192 2 SNMSLVFAVNGERFELSSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLLSKYDPVLDQVEDFTVSSCLTLLCSVN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 87 EAAVTTVEGIGSTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRN-----IPEP-------TMEDIQEALGGNLCR 154
Cdd:PLN00192 82 GCSITTSEGLGNSKDGFHPIHKRFAGFHASQCGFCTPGMCISLFSALVNadktdRPEPpsgfsklTVVEAEKAVSGNLCR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 155 CTGYRPILDGYKTFCgasnccqtnSNGDCclnEEL-------LGQDKENVFSElfnkddLIPLDPTQELIFPPELIimaE 227
Cdd:PLN00192 162 CTGYRPIVDACKSFA---------ADVDI---EDLglnsfwkKGESEEAKLSK------LPPYNHSDHICTFPEFL---K 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 228 KQERKSLTFRGERITWISPVSLEELIQL-KSSYPNA---PLVIGNTNIGpeiKFKGI-LHPVIISPTRISELYNVMKTTE 302
Cdd:PLN00192 221 KEIKSSLLLDSSRYRWYTPVSVEELQSLlESNNFDGvsvKLVVGNTGTG---YYKDEeLYDKYIDIRHIPELSMIRRDEK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 303 GVSIGAGCSLSTVIKLL-EELVSSLpeeeteIFRALLKQMKNVGGQQIRNVASLGANIVSAHPN---SDLNPVLAAANCT 378
Cdd:PLN00192 298 GIEIGAVVTISKAIEALrEESKSEY------VFKKIADHMEKIASRFVRNTGSIGGNLVMAQRKqfpSDIATILLAAGST 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 379 LSVVSQGGKENIILnEDFfvgFGKTALTPDEILVSVFIPFSKRGE------FVRVFRQAPRQ-ENAFCSVNSGMKVQFK- 450
Cdd:PLN00192 372 VNIQNASKREKLTL-EEF---LERPPLDSKSLLLSVEIPSWTSSSgsdtklLFETYRAAPRPlGNALPYLNAAFLAEVSq 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 451 ---EGTAVVEDLSIFYGGVGP-CTVKAKKTCQEIIGRPWNEKTISEAYRLLLDEIElpPSAPGGMVEFRRALTLSFLFKF 526
Cdd:PLN00192 448 dasSGGIVVNDCRLAFGAYGTkHAIRARKVEEFLTGKVLSDSVLYEAVRLLKGIVV--PEDGTSHPEYRSSLAVGFLFDF 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 527 ylemLQKLGEMNVTLEDVPGEFASAIRFFPQKREH---------SVQefQVVAHDQpcWDPVGHPIMHRSAISQATGEAV 597
Cdd:PLN00192 526 ----LSPLIESNAKSSNGWLDGGSNTKQNPDQHDDvkkptlllsSKQ--QVEENNE--YHPVGEPIKKVGAALQASGEAV 597
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 598 YCDDIPKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIP--GKKFRTFTNIDEELLAENEVS-CVGQLV 674
Cdd:PLN00192 598 YVDDIPSPKNCLYGAFIYSTKPLARVKGIKFKSNLVPQGVLAVITFKDIPkgGQNIGSKTIFGPEPLFADEVTrCAGQRI 677
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 675 CAVVADTKPHAKRGAAAIKITY--EDLQPLIFTIQEAIEKQSFFK--PQRRIEK-GNVEEAFEKAD-QVLEGEIQIGGQE 748
Cdd:PLN00192 678 ALVVADTQKHADMAANLAVVEYdtENLEPPILTVEDAVKRSSLFEvpPFLYPKPvGDISKGMAEADhKILSAEIKLGSQY 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 749 HFYMETQSMLVIPvQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVKRLGGAFGGKVTRTSVMASITAVAAWKTD 828
Cdd:PLN00192 758 YFYMETQTALALP-DEDNCIVVYSSTQCPEYVHSVIARCLGIPEHNVRVITRRVGGGFGGKAVKSMPVATACALAAFKLQ 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 829 RAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGDESiLVIEKILLHMDNSYNIPNLRGMSTA 908
Cdd:PLN00192 837 RPVRMYLNRKTDMIMAGGRHPMKITYSVGFKSDGKITALHLDILINAGISPDIS-PIMPRNIIGALKKYDWGALSFDIKV 915
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 909 CRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGTSCT--HYKLAFDPH--NLWRCWDECLEKSA 984
Cdd:PLN00192 916 CKTNLSSRSAMRAPGEVQGSYIAEAIIEHVASTLSMDVDSVRKINLHTYESLKlfYGDSAGEPSeyTLPSIWDKLASSSE 995
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 985 FSNRRIAINKFNKQNRWKKRGIAVVPIKYGIafaesFLNQAAALVHIYKDGSVLLSHGGTEMGQGIHTKMQQVASREL-- 1062
Cdd:PLN00192 996 FKQRTEMVKEFNRSNKWKKRGISRVPIVHEV-----MLRPTPGKVSILSDGSIAVEVGGIEIGQGLWTKVKQMAAFGLgm 1070
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1063 -----------RIPA------SFIHISETSTNTVPNTCPSaasfgtdangmAVKDACQTLLQRLEPIIH--DNPKG--TW 1121
Cdd:PLN00192 1071 ikcdggedlldKIRViqsdtlSMIQGGFTAGSTTSESSCE-----------AVRLCCVILVERLKPIKErlQEQMGsvTW 1139
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1122 QDWIKTAYFQKISLSSTGFYRGHDLYMDwekqegrpyaYFTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINPSVDIG 1201
Cdd:PLN00192 1140 DMLISQAYMQSVNLSASSYYTPDPSSME----------YLNYGAAVSEVEVDLLTGETTILRSDIIYDCGQSLNPAVDLG 1209
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1202 QIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVPLTFNVYLLAGSQNPHAIYSSKGIGEPVLFLGSSVFFA 1281
Cdd:PLN00192 1210 QIEGAFVQGIGFFMLEEYTTNSDGLVVTDGTWTYKIPTVDTIPKQFNVEILNSGHHKKRVLSSKASGEPPLLLAASVHCA 1289
|
1370 1380 1390
....*....|....*....|....*....|..
gi 973181399 1282 IKDAVSAARKERDLKG-------PFRLDSPAT 1306
Cdd:PLN00192 1290 TRAAIREARKQLLSWGgidgsdsTFQLPVPAT 1321
|
|
| CoxL |
COG1529 |
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ... |
576-1310 |
4.84e-152 |
|
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain] Cd Length: 741 Bit Score: 477.03 E-value: 4.84e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 576 WDPVGHPIMHRSAISQATGEAVYCDDIpKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKFRT-F 654
Cdd:COG1529 7 FRIIGKPVPRVDGPAKVTGRARYTDDI-RLPGMLYAAVVRSPHAHARIKSIDTSAALALPGVVAVLTGEDLPGLKFGLpG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 655 TNIDEELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLqPLIFTIQEAI---------EKQSFFKPQRRIEKG 725
Cdd:COG1529 86 PDPDQPPLADDKVRYVGEPVAAVVAETREAARDAAELIKVEYEPL-PAVVDPEAALapgaplvheELPGNVAAEWRGERG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 726 NVEEAFEKADQVLEGEIQIGGQEHFYMETQSMLVIPvQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVKRLGGA 805
Cdd:COG1529 165 DVDAAFAEADVVVEATYTTPRLAHAPMEPRAAVAEW-DGDGRLTVWASTQGPHLVRRALARALGLPPEKVRVIAPDVGGG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 806 FGGKVTrTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGDESILV 885
Cdd:COG1529 244 FGGKLD-VYPEEVLAALAARKLGRPVKLVLTREEDFLADTHRHATVQRVRLGADKDGKITALRHDVVADTGAYASFGEAV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 886 IEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYRGTSCTHYKL 965
Cdd:COG1529 323 LPLGATMATGPYAIPNVRVEARAVYTNTPPTGAYRGPGRPQAAFALESAMDELAEELGMDPVELRLRNLIRPGDFPPTGQ 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 966 AFDPHNLWRCWDECLEKSAFSNRRiAINKFNKQNRWKKRGIAVvpikyGIAFAESFLNQAAALVHIYKDGSVLLSHGGTE 1045
Cdd:COG1529 403 PYDSGRLAECLEKAAEAFGWGERR-ARPAEARAGKLRGIGVAA-----YIEGSGGGGDPESARVRLNPDGSVTVYTGATD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1046 MGQGIHTKMQQVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRL------------EPII 1113
Cdd:COG1529 477 IGQGHETVLAQIAAEELGVPPEDVRVVLGDTDLTPYGGGTGGSRSTAVGGSAVRKAAEKLREKLlelaahllgadpEDLE 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1114 HDNPK-------GTWQDWIKTAYFqkISLSSTGFYRGHDlymdwekqegrpYAYFTYGVSCSEVEIDCLTGDHKNIRADI 1186
Cdd:COG1529 557 FEDGRvrvpgrsVSLAELAAAAYY--GGLEATGTYDPPT------------YPTYSFGAHVAEVEVDPETGEVRVLRVVA 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1187 VMDTGRSINPSVDIGQIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVPlTFNVYLLAgSQNPHAIYSSKG 1266
Cdd:COG1529 623 VHDCGRVINPLLVEGQVEGGVVQGIGQALYEELVYDEDGQLLNANFADYLVPRAADVP-EIEVIFVE-TPDPTNPLGAKG 700
|
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 973181399 1267 IGEPVLflgSSVFFAIKDAVSAA--RKERDLkgpfrldsPATAEKI 1310
Cdd:COG1529 701 VGEPGT---IGVAPAIANAVYDAtgVRIRDL--------PITPEKV 735
|
|
| xanthine_xdhA |
TIGR02963 |
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ... |
11-529 |
1.81e-141 |
|
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 274365 [Multi-domain] Cd Length: 467 Bit Score: 439.40 E-value: 1.81e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 11 LVFFVNGKKVVEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYQPQTKsILHFSANACLLPICLLTEAAV 90
Cdd:TIGR02963 1 IRFFLNGETVTLSDVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVGELVDGGK-LRYRSVNACIQFLPSLDGKAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 91 TTVEGIGSTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYKTFCg 170
Cdd:TIGR02963 80 VTVEDLRQPDGRLHPVQQAMVECHGSQCGFCTPGFVMSLYALYKNSPAPSRADIEDALQGNLCRCTGYRPILDAAEAAF- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 171 ASNCCQtnsngdcclneellgqdkenvfselfnkddliPLDPTQELIFPpelIIMAEKQ-ERKSLTFRGERItwISPVSL 249
Cdd:TIGR02963 159 DYPCSD--------------------------------PLDADRAPIIE---RLRALRAgETVELNFGGERF--IAPTTL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 250 EELIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEGVSIGAGCSLSTVIKLLEELVSSLPEe 329
Cdd:TIGR02963 202 DDLAALKAAHPDARIVAGSTDVGLWVTKQMRDLPDVIYVGQVAELKRIEETDDGIEIGAAVTLTDAYAALAKRYPELGE- 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 330 eteifrallkQMKNVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILnEDFFVGFGKTALTPDE 409
Cdd:TIGR02963 281 ----------LLRRFASLQIRNAGTLGGNIANGSPIGDSPPALIALGARLTLRKGEGRRTLPL-EDFFIDYGKTDRQPGE 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 410 ILVSVFIPFSKRGEFVRVFRQAPRQENAFCSVNSGMKVQFKEGtaVVEDLSIFYGGVGPCTVKAKKTCQEIIGRPWNEKT 489
Cdd:TIGR02963 350 FVEALHVPRPTPGERFRAYKISKRFDDDISAVCAAFNLELDGG--VVAEIRIAFGGMAATPKRAAATEAALLGKPWNEAT 427
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 973181399 490 ISEAYRLLLDEIE-LPPSAPGGmvEFRRALTLSFLFKFYLE 529
Cdd:TIGR02963 428 VEAAMAALAGDFTpLSDMRASA--EYRLLTAKNLLRRFFLE 466
|
|
| MoCoBD_2 |
pfam20256 |
Molybdopterin cofactor-binding domain; |
978-1244 |
3.95e-114 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain] Cd Length: 282 Bit Score: 358.77 E-value: 3.95e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 978 ECLEKSAFSNRRIAINKFNKQNRwkKRGIAVVPIKYGIAFAESFLNQAAALVHIYKDGSVLLSHGGTEMGQGIHTKMQQV 1057
Cdd:pfam20256 1 KALELSDYDERRAEQAEFNRGNR--KRGIGIAPYVEGSGLGPGALNQAGALVRLNPDGSVTVYTGGTEMGQGLETKLAQI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1058 ASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRLEPIIH--------------------DNP 1117
Cdd:pfam20256 79 AAEALGIPPEDVRVVEGDTDTVPNGGGTGASRSTDVGGNAVLLAAEKLRERLLKIAAhlleaspedlefedgkvyvkGDP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1118 KG-TWQDWIKTAYFQKISLSSTGFYRGHdlymDWEKQEGRPYAYFTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINP 1196
Cdd:pfam20256 159 RSvTFAELAAAAYGEGVGLSATGFYTPP----DDETGQGPPFAYYPYGAHAAEVEVDPETGEVRVLRYVAVHDCGRVINP 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 973181399 1197 SVDIGQIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDVP 1244
Cdd:pfam20256 235 AIVEGQIEGGFVQGIGLALMEELVYDEDGQLLTASLMDYKIPTAADIP 282
|
|
| MoCoBD_1 |
pfam02738 |
Molybdopterin cofactor-binding domain; |
721-954 |
1.66e-103 |
|
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain] Cd Length: 244 Bit Score: 328.26 E-value: 1.66e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 721 RIEKGNVEEAFEKADQVLEGEIQIGGQEHFYMETQSMLVIPVQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVK 800
Cdd:pfam02738 12 HREKGDVEAAFAEADHVVEGEYRTGRQEHFYMETRAALAVPDDEDGRLTVYSSTQGPHLVRRLVARVLGIPENKVRVIVP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 801 RLGGAFGGKvTRTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGD 880
Cdd:pfam02738 92 RVGGGFGGK-TQSYPEEALAALAARKTGRPVKWVLDREEDMLATGHRHPFLIKYKVGADKDGKILALDVDLYADGGAYAD 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 973181399 881 ESILVIEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINM 954
Cdd:pfam02738 171 LSPAVPERALSHLDGPYKIPNVRVDGRAVYTNTPPNGAFRGFGRPQGMFALERLMDELAEELGMDPLELRRRNL 244
|
|
| XdhA |
COG4630 |
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ... |
13-540 |
2.19e-99 |
|
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];
Pssm-ID: 443668 [Multi-domain] Cd Length: 476 Bit Score: 326.32 E-value: 2.19e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 13 FFVNGKKVVEKNADPETTLLSYIREKLRLTGTKyacggggcgacTVMVSKyqpQTKSILHFSA-NACLLPICLLTEAAVT 91
Cdd:COG4630 3 FLLNGELVELSDVPPTTTLLDWLREDRGLTGTKegcaegdcgacTVVVGE---LDDGGLRYRAvNACILFLPQLDGKALV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 92 TVEGIGSTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYKTFCGA 171
Cdd:COG4630 80 TVEGLAGPDGALHPVQQAMVDHHGSQCGFCTPGFVMSLFALYERGPAPDRADIEDALSGNLCRCTGYRPIIDAARAMAEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 172 SnccqtnsngdcclneellgqdkenvfselfnKDDLIPLDPTQELIFPPELiimaekQERKSLTFRGERITWISPVSLEE 251
Cdd:COG4630 160 P-------------------------------APDPFAADRAAVAAALRAL------ADGETVELGAGGSRFLAPATLDE 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 252 LIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEGVSIGAGCSLStviKLLEELVSSLPEeet 331
Cdd:COG4630 203 LAALLAAHPDARLVAGATDVGLWVTKQLRDLPPVIFLGRVAELRRIEETDDGLEIGAAVTLS---DAEAALAAHFPE--- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 332 eiFRALLKQMknvGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILnEDFFVGFGKTALTPDEIL 411
Cdd:COG4630 277 --LAELLRRF---ASRQIRNAGTLGGNIANGSPIGDSPPALIALGAELVLRSGDGRRTLPL-EDFFLGYRKTDLQPGEFV 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 412 VSVFIPFSKRGEFVRVFRQAPRQENAFCSVNSGMKVQFKEGTavVEDLSIFYGGVGPCTVKAKKTCQEIIGRPWNEKTIS 491
Cdd:COG4630 351 EAIRIPLPAAGQRLRAYKVSKRFDDDISAVCAAFALTLDDGT--VTEARIAFGGMAATPKRARAAEAALLGQPWTEATVA 428
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 973181399 492 EAYRLLLDEIElpP------SApggmvEFRRALTLSFLFKFYLEMLQKLGEMNVT 540
Cdd:COG4630 429 AAAAALAQDFT--PlsdmraSA-----EYRLAVAANLLRRFFLETQGEAPATRVA 476
|
|
| PRK09970 |
PRK09970 |
xanthine dehydrogenase subunit XdhA; Provisional |
579-1289 |
1.56e-72 |
|
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain] Cd Length: 759 Bit Score: 258.47 E-value: 1.56e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 579 VGHPIMHRSAISQATGEAVYCDDIPKtEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKFRT----- 653
Cdd:PRK09970 3 IGKSIMRVDAIAKVTGRAKYTDDYVM-AGMLYAKYVRSPIAHGKVKSIDTEEARSLPGVEAVFTWEDVPDIPFPTaghpw 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 654 -----FTNIDEELLAENEVSCVGQLVCAVVADTKPHAKRGAAAIKITYEDLqPLIFTIQEAI--------EKQSFFKPQR 720
Cdd:PRK09970 82 sldpnHRDIADRALLTRHVRHHGDAVAAVVARDELTAEKALKLIKVEYEEL-PVITDPEAALaegappihNGRGNLLKQS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 721 RIEKGNVEEAFEKADQVLEGEIQIGGQEHFYMETQSMLVIpVQEDKEFKVFIATQHPSYTQEAVAETLGIPSNRVSCHVK 800
Cdd:PRK09970 161 TMSTGNVQQTIKAADYQVQGHYETPIVQHCHMENVTSYAY-MEDDGRITIVSSTQIPHIVRRVVGQALGIPWGKVRVIKP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 801 RLGGAFGGK--VTRTSVMASITAVAAwktDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNT 878
Cdd:PRK09970 240 YVGGGFGNKqdVLEEPLAAFLTSKVG---GRPVKVSLSREECFLATRTRHAFTIDIKMGVNRDGTLKGYSLDVLSNTGAY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 879 GDESILVIEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREINMYR-G 957
Cdd:PRK09970 317 ASHGHSIASAGGNKVAYLYPRCAYKYSSKTVYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEFRLRNAAReG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 958 TScthyklafDP--HNLWRC--WDECLEKSA----FSNRRiaiNKFNKQNRWKKRGIAVVPIKYG---------IAFAES 1020
Cdd:PRK09970 397 DA--------NPlsGKRIYSagLPECLEKGRkifeWDKRR---AECKNQQGNLRRGVGVACFSYTsgtwpvgleIAGARL 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1021 FLNQaaalvhiykDGSVLLSHGGTEMGQGIHTKMQQVASRELRIPASFIH-ISETSTNTVPNTCPSAASFGTDANGMAVK 1099
Cdd:PRK09970 466 LMNQ---------DGTVQVQSGATEIGQGSDTVFSQMVAETVGIPVSDVRvISTQDTDVTPFDPGAYASRQSYVAGPAIR 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1100 DACQTLLQRLEPIIHDnpkgtwqdwiktayFQKISLSSTGFYRGHDLYmdweKQEGRPY---------AY---------- 1160
Cdd:PRK09970 537 KAALELKEKILAHAAV--------------MLHQSAMNLDIIDGHIVV----KRPGEPLmsleelamdAYyhperggqit 598
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1161 -----------FTYGVSCSEVEIDCLTGDHKNIRADIVMDTGRSINPSVDIGQIEGAFIQGLGLYTMEELKFSP-SGVLY 1228
Cdd:PRK09970 599 aessiktttnpPAFGCTFVDVEVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDEkTGVVR 678
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973181399 1229 TRGPAQYKIPAVCDVPlTFNVYLLAgSQNPHAIYSSKGIGEPVLFlgsSVFFAIKDAVSAA 1289
Cdd:PRK09970 679 NPNLLDYKLPTMMDLP-QLESAFVE-IYEPQSAYGHKSLGEPPII---SPAPAIRNAVLMA 734
|
|
| FAD_binding_5 |
pfam00941 |
FAD binding domain in molybdopterin dehydrogenase; |
240-419 |
5.09e-54 |
|
FAD binding domain in molybdopterin dehydrogenase;
Pssm-ID: 460007 [Multi-domain] Cd Length: 170 Bit Score: 186.21 E-value: 5.09e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 240 RITWISPVSLEELIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEGVSIGAGCSLSTVI-KL 318
Cdd:pfam00941 2 KFGYYRPASLAEALELLAAGPDAKLVAGGTSLGPLMKLRLARPDHLIDINGIPELRGIEETDGGLEIGAAVTLSEIAePL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 319 LEELVSSLPEeeteifrallkQMKNVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILnEDFFV 398
Cdd:pfam00941 82 LREAYPALSE-----------ALRKIASPQIRNVGTIGGNIANASPISDLPPALLALDAKVELRSGEGERTVPL-EDFFL 149
|
170 180
....*....|....*....|.
gi 973181399 399 GFGKTALTPDEILVSVFIPFS 419
Cdd:pfam00941 150 GYGKTALEPGELITAVIIPLP 170
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
613-1313 |
7.20e-44 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 173.86 E-value: 7.20e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 613 LVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIP-------GKKFRTFTNIDEELLAEnEVSCVGQLVCAVVADTKPHA 685
Cdd:PRK09800 205 MLRSPHAHALITHLDVSKAEALPGVVHVITHLNCPdiyytpgGQSAPEPSPLDRRMFGK-KMRHVGDRVAAVVAESEEIA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 686 KRGAAAIKITYEDLQPlIFTIQEA----------------------IEKQSFFKPQR----------------------R 721
Cdd:PRK09800 284 LEALKLIDVEYEVLKP-VMSIDEAmaedapvvhdepvvyvagapdtLEDDNSHAAQRgehmiinfpigsrprkniaasiH 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 722 IEKGNVEEAFEKADQVLEGEIQIGGQEHFYMETQsmlVIPVQEDKEFKVFIA-TQHPSYTQEAVAETLGIPSNRVSCHVK 800
Cdd:PRK09800 363 GHIGDMDKGFADADVIIERTYNSTQAQQCPTETH---ICFTRMDGDRLVIHAsTQVPWHLRRQVARLVGMKQHKVHVIKE 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 801 RLGGAFGGKvtRTSVMASITAVAAWKTDRAVRCVLERGEDMLITGGRHPVLAKYKVGFMNNGQIIAADVHYYTNAGNTGD 880
Cdd:PRK09800 440 RVGGGFGSK--QDILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGN 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 881 ESILVIEKILLHMDNSYNIPNLRGMSTACRTNLPSNTAFRGFGVPQSMLVTESWINDVAVRVGCSAEKIREIN-MYRGT- 958
Cdd:PRK09800 518 HSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNFAITMALAELAEQLQIDQLEIIERNrVHEGQe 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 959 -----SCTHYKLAFDPHNLWRC-WDECLEKSAfsnRRIAINKFNKQN-RWK-KRGIAVVPIKYGIafaeSFLNQAAALVH 1030
Cdd:PRK09800 598 lkilgAIGEGKAPTSVPSAASCaLEEILRQGR---EMIQWSSPKPQNgDWHiGRGVAIIMQKSGI----PDIDQANCMIK 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1031 IYKDGSVLLSHGGTEMGQGIHTKMQQVASRELRIPASFIHISETSTNTVPNTCPSAASFGTDANGMAVKDACQTLLQRL- 1109
Cdd:PRK09800 671 LESDGTFIVHSGGADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARLAAENLREKIl 750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1110 --------EPIihdnpkgtwqdwiktayfQKISLSSTGFYRGH-------DLYMDWEKQEG-----------RPYAYFTY 1163
Cdd:PRK09800 751 fhgaqmlgEPV------------------ADVQLATPGVVRGKkgevsfgDIAHKGETGTGfgslvgtgsyiTPDFAFPY 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 1164 GVSCSEVEIDCLTGDHKNIRADIVMDTGRSINPSVDIGQIEGAFIQGLGLYTMEELKFSPSGVLYTRGPAQYKIPAVCDV 1243
Cdd:PRK09800 813 GANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDI 892
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973181399 1244 PLTFNVYLLAgSQNPHAIYSSKGIGE-PVLFLGSSVFFAIKDAVsaarkerdlkGPFRLDSPATAEKICHA 1313
Cdd:PRK09800 893 PRDFRAVLVP-SDDKVGPFGAKSISEiGVNGAAPAIATAIHDAC----------GIWLREWHFTPEKILTA 952
|
|
| Ald_Xan_dh_C |
smart01008 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ... |
593-699 |
1.42e-43 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain] Cd Length: 107 Bit Score: 153.83 E-value: 1.42e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 593 TGEAVYCDDIpKTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKFRTFTNIDEELLAENEVSCVGQ 672
Cdd:smart01008 1 TGEARYGDDI-RLPGMLHAAVVRSPVAHARIKSIDTSAARAMPGVVAVLTAKDVPGLNDFGPLGPDEPVLADDKVRYVGQ 79
|
90 100
....*....|....*....|....*..
gi 973181399 673 LVCAVVADTKPHAKRGAAAIKITYEDL 699
Cdd:smart01008 80 PVAAVVAETEEAARDAAEAVKVEYEEL 106
|
|
| CutS |
COG2080 |
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ... |
13-163 |
1.24e-42 |
|
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441683 [Multi-domain] Cd Length: 155 Bit Score: 152.94 E-value: 1.24e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 13 FFVNGKKVvEKNADPETTLLSYIREKLRLTGTKYacggggcgacTVMVSKyQPqtksilhfsANACLLPICLLTEAAVTT 92
Cdd:COG2080 6 LTVNGKPV-EVDVDPDTPLLDVLRDDLGLTGTKFgcghgqcgacTVLVDG-KA---------VRSCLTLAVQADGKEITT 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973181399 93 VEGIGSTKtRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILD 163
Cdd:COG2080 75 IEGLAEDG-ELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNPTEEEIREALSGNLCRCTGYVRIVR 144
|
|
| Ald_Xan_dh_C |
pfam01315 |
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; |
593-700 |
1.69e-39 |
|
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain] Cd Length: 107 Bit Score: 141.99 E-value: 1.69e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 593 TGEAVYCDDIPkTEGELFLVLVTSTRPHAKLIGIDTSEALKVPGVVDVITAKDIPGKKFRTFTNIDEELLAENEVSCVGQ 672
Cdd:pfam01315 1 TGEAVYVDDIP-APGNLYGAFVRSTIAHAKIVSIDTSAALALPGVVAVITAKDLPGGNYNIGPIPLDPLFATDKVRHVGQ 79
|
90 100
....*....|....*....|....*...
gi 973181399 673 LVCAVVADTKPHAKRGAAAIKITYEDLQ 700
Cdd:pfam01315 80 PIAAVVADDEETARRAAKLVKVEYEELP 107
|
|
| CutB |
COG1319 |
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion] ... |
240-518 |
2.29e-39 |
|
Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, FAD-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 440930 [Multi-domain] Cd Length: 285 Bit Score: 148.35 E-value: 2.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 240 RITWISPVSLEELIQLKSSY-PNAPLVIGNTNIGPEIKFkGILHP-VIISPTRISELYNVMKTTEGVSIGAGCSLSTVI- 316
Cdd:COG1319 3 PFEYHRPTSLEEALALLAEHgPDARVLAGGTDLLPLMKL-RLARPeHLVDINRIPELRGIEEEGGGLRIGALVTHAELAa 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 317 -KLLEELVSSLPEeeteifrALLKqmknVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGKENIILnED 395
Cdd:COG1319 82 sPLVRERYPLLAE-------AARA----IASPQIRNRGTIGGNLANADPAADLPPALLALDATVELAGPDGERTIPA-AD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 396 FFVGFGKTALTPDEILVSVFIPFSKRGEFVRVFRQAPRQENAFCSVNSGMKVQFKEGTavVEDLSIFYGGVGPCTVKAKK 475
Cdd:COG1319 150 FFLGPGETALEPGELITAVRLPAPPAGAGSAYLKVGRRASDAIALVSVAVALRLDGGT--IRDARIALGGVAPTPWRARE 227
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 973181399 476 TCQEIIGRPWNEKTISEAYRLLLDEIElPPSAPGGMVEFRRAL 518
Cdd:COG1319 228 AEAALAGKPLSEEAIEAAAEAAAAAAD-PIDDVRASAEYRRHL 269
|
|
| Fer2_2 |
pfam01799 |
[2Fe-2S] binding domain; |
92-163 |
1.09e-35 |
|
[2Fe-2S] binding domain;
Pssm-ID: 460336 [Multi-domain] Cd Length: 73 Bit Score: 129.86 E-value: 1.09e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 973181399 92 TVEGIGSTKTriHPVQERIAKAHGSQCGFCTPGMVMSMYTLL-RNIPEPTMEDIQEALGGNLCRCTGYRPILD 163
Cdd:pfam01799 1 TIEGLAESGG--EPVQQAFAEAGAVQCGYCTPGMIMSAYALLeRNPPPPTEAEIREALSGNLCRCTGYRRIVD 71
|
|
| CO_deh_flav_C |
pfam03450 |
CO dehydrogenase flavoprotein C-terminal domain; |
426-529 |
1.38e-33 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 460921 [Multi-domain] Cd Length: 102 Bit Score: 124.98 E-value: 1.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 426 RVFRQAPRQENAFCSVNSGMKVQFKEGTavVEDLSIFYGGVGPCTVKAKKTCQEIIGRPWNEKTISEAYRLLLDEIElPP 505
Cdd:pfam03450 1 AAYKQAKRRDDDIAIVNAAFRVRLDGGT--VEDARIAFGGVAPTPIRATEAEAALIGKPWDEETLEAAAALLLEDLS-PL 77
|
90 100
....*....|....*....|....
gi 973181399 506 SAPGGMVEFRRALTLSFLFKFYLE 529
Cdd:pfam03450 78 SDPRGSAEYRRHLARSLLFRFLLE 101
|
|
| glyceraldDH_gamma |
NF041020 |
glyceraldehyde dehydrogenase subunit gamma; |
15-166 |
1.12e-28 |
|
glyceraldehyde dehydrogenase subunit gamma;
Pssm-ID: 468949 [Multi-domain] Cd Length: 162 Bit Score: 113.35 E-value: 1.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 15 VNGKKVvEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYQPQTKSILHFSANAcllpicllteAAVTTVE 94
Cdd:NF041020 15 VNGVWY-EAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADG----------AEITTIE 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 973181399 95 GIGStKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYK 166
Cdd:NF041020 84 GLSK-DGKLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKENPNPTEEEIRDGIHGNLCRCTGYQNIVKAVK 154
|
|
| pucE |
TIGR03198 |
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ... |
9-169 |
1.41e-25 |
|
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.
Pssm-ID: 132242 [Multi-domain] Cd Length: 151 Bit Score: 104.16 E-value: 1.41e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 9 ENLVFFVNGKKVvEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYqpqtksilhfSANACLLPICLLTEA 88
Cdd:TIGR03198 2 EQFRFTVNGQAW-EVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGK----------LANACLTMAYQADGH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 89 AVTTVEGIgsTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYKTF 168
Cdd:TIGR03198 71 EITTIEGI--AENELDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETPQPSDEDMEEGLSGNLCRCTGYGGIIRSACRI 148
|
.
gi 973181399 169 C 169
Cdd:TIGR03198 149 R 149
|
|
| CO_deh_flav_C |
smart01092 |
CO dehydrogenase flavoprotein C-terminal domain; |
428-529 |
2.57e-25 |
|
CO dehydrogenase flavoprotein C-terminal domain;
Pssm-ID: 215021 [Multi-domain] Cd Length: 102 Bit Score: 101.54 E-value: 2.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 428 FRQAPRQENAFCSVNSGMKVQFKEGTavVEDLSIFYGGVGPCTVKAKKTCQEIIGRPWNEKTISEAYRLLLDEIELPPSA 507
Cdd:smart01092 2 YKKSRRRDGDIALVSAAVALTLDGGR--VTEARIALGGVAPTPKRAAEAEAALVGKPLTDEALARAAAAALAQDFTPLSD 79
|
90 100
....*....|....*....|..
gi 973181399 508 PGGMVEFRRALTLSFLFKFYLE 529
Cdd:smart01092 80 MRASAEYRRQLAANLLRRALLE 101
|
|
| Se_dep_XDH |
TIGR03311 |
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional ... |
13-181 |
6.01e-24 |
|
selenium-dependent xanthine dehydrogenase; Members of this protein resemble conventional xanthine dehydrogenase enzymes, which depend on molybdenum cofactor - molybdopterin bound to molybdate with two sulfur atoms as ligands. But all members of this family occur in species that contain markers for the biosynthesis of enzymes with a selenium-containing form of molybdenum cofactor. The member of this family from Enterococcus faecalis has been shown to act as a xanthine dehydrogenenase, and its activity if dependent on SelD (selenophosphate synthase), selenium, and molybdenum. [Purines, pyrimidines, nucleosides, and nucleotides, Other]
Pssm-ID: 132354 [Multi-domain] Cd Length: 848 Bit Score: 109.55 E-value: 6.01e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 13 FFVNGKKVVeknADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYqpqtksilhfSANACLLPICLLTEAAVTT 92
Cdd:TIGR03311 3 FIVNGREVD---VNEEKKLLEFLREDLRLTGVKNGCGEGACGACTVIVNGK----------AVRACRFTTAKLAGKEITT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 93 VEGIGSTKTRIHPVQerIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGY----KTF 168
Cdd:TIGR03311 70 VEGLTEREKDVYAWA--FAKAGAVQCGFCIPGMVISAKALLDKNPNPTEAEIKKALKGNICRCTGYVKIIKAVrlaaKAF 147
|
170
....*....|...
gi 973181399 169 CGASNCCQTNSNG 181
Cdd:TIGR03311 148 REEIEPPRGEPKG 160
|
|
| 4hydroxCoAred |
TIGR03193 |
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts ... |
15-167 |
1.69e-23 |
|
4-hydroxybenzoyl-CoA reductase, gamma subunit; 4-hydroxybenzoyl-CoA reductase converts 4-hydroxybenzoyl-CoA to benzoyl-CoA, a common intermediate in the degradation of aromatic compounds. This protein family represents the gamma chain of this three-subunit enzyme.
Pssm-ID: 132237 [Multi-domain] Cd Length: 148 Bit Score: 98.03 E-value: 1.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 15 VNGKKVVEKNADpETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKyQPqtksilhfsANACLLPICLLTEAAVTTVE 94
Cdd:TIGR03193 6 VNGRWREDAVAD-NMLLVDYLRDTVGLTGTKQGCDGGECGACTVLVDG-RP---------RLACSTLAHRVAGRKVETVE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 973181399 95 GIgSTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCRCTGYRPILDGYKT 167
Cdd:TIGR03193 75 GL-ATNGRLSRLQQAFHERLGTQCGFCTPGMIMAAEALLRRNPSPSRDEIRAALAGNLCRCTGYVKIIESVEA 146
|
|
| PRK09971 |
PRK09971 |
xanthine dehydrogenase subunit XdhB; Provisional |
246-501 |
2.37e-23 |
|
xanthine dehydrogenase subunit XdhB; Provisional
Pssm-ID: 182175 [Multi-domain] Cd Length: 291 Bit Score: 102.04 E-value: 2.37e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 246 PVSLEELIQLKSSYPNAPLVIGNTNIGPEIKFKGILHPVIISPTRISELYNVMKTTEG-VSIGAGCSLSTVIklleelvs 324
Cdd:PRK09971 10 AATLEEAIELLADNPQAKLIAGGTDVLIQLHHHNDRYRHLVSIHNIAELRGITLAEDGsIRIGAATTFTQII-------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 325 slpeeETEIFRALLKQMK----NVGGQQIRNVASLGANIVSAHPNSDLNPVLAAANCTLSVVSQGGkENIILNEDFFVGF 400
Cdd:PRK09971 82 -----EDPIIQKHLPALAeaavSIGGPQIRNVATIGGNICNGATSADSAPPLFALDAKLEIHSPNG-VRFVPINGFYTGP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 401 GKTALTPDEILVSVFI-PFSKRGEFVRVFRQAPRqeNAF------CSVNsgmkVQFKEGTavVEDLSIFYGGVGPCTVKA 473
Cdd:PRK09971 156 GKVSLEHDEILVAFIIpPEPYEHAGGAYIKYAMR--DAMdiatigCAVL----CRLDNGN--FEDLRLAFGVAAPTPIRC 227
|
250 260
....*....|....*....|....*...
gi 973181399 474 KKTCQEIIGRPWNEKTISEAYRLLLDEI 501
Cdd:PRK09971 228 QHAEQTAKGAPLNLETLEAIGELVLQDV 255
|
|
| PRK11433 |
PRK11433 |
aldehyde oxidoreductase 2Fe-2S subunit; Provisional |
7-163 |
4.55e-23 |
|
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
Pssm-ID: 236910 [Multi-domain] Cd Length: 217 Bit Score: 99.08 E-value: 4.55e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 7 SSENLVFFVNGKkVVEKNADPETTLLSYIREKLRLTGTKYACGGGGCGACTVMVSKYQpqtksilhfsANACLLPICLLT 86
Cdd:PRK11433 48 EISPVTLKVNGK-TEQLEVDTRTTLLDALREHLHLTGTKKGCDHGQCGACTVLVNGRR----------LNACLTLAVMHQ 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 87 EAAVTTVEGIGsTKTRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLL----RNIP-----------EPTMEDIQEALGGN 151
Cdd:PRK11433 117 GAEITTIEGLG-SPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAVLkeikDGIPshvtvdltaapELTADEIRERMSGN 195
|
170
....*....|..
gi 973181399 152 LCRCTGYRPILD 163
Cdd:PRK11433 196 ICRCGAYSNILE 207
|
|
| PRK09908 |
PRK09908 |
xanthine dehydrogenase iron sulfur-binding subunit XdhC; |
90-177 |
9.43e-15 |
|
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
Pssm-ID: 182139 [Multi-domain] Cd Length: 159 Bit Score: 73.03 E-value: 9.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 90 VTTVEGIGSTKtRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEP--TMEDIQEALGGNLCRCTGYRPILDGYKt 167
Cdd:PRK09908 76 IRTLEGEAKGG-KLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKplTITEIRRGLAGNLCRCTGYQMIVNTVL- 153
|
90
....*....|
gi 973181399 168 fcgasNCCQT 177
Cdd:PRK09908 154 -----DCEKT 158
|
|
| PRK09800 |
PRK09800 |
putative hypoxanthine oxidase; Provisional |
75-159 |
1.39e-05 |
|
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain] Cd Length: 956 Bit Score: 49.83 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973181399 75 ANACLLPICLLTEAAVTTVEGIGSTKtRIHPVQERIAKAHGSQCGFCTPGMVMSMYTLLRNIPEPTMEDIQEALGGNLCR 154
Cdd:PRK09800 56 VNASLLIAAQLEKADIRTAESLGKWN-ELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSR 134
|
....*
gi 973181399 155 CTGYR 159
Cdd:PRK09800 135 DAGWQ 139
|
|
| |
