Helix-loop-helix DNA-binding domain;

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1034631754   20 RETHNAVERHRKKKINAGINRIGELIPCSPAL-KQSKNMILDQAFKYITELK 70
Cdd:pfam00010    2 REAHNERERRRRDRINDAFDELRELLPTLPPDkKLSKAEILRLAIEYIKHLQ 53

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   12 KKQHRKKNRETHNAVE-----RHRKKKINAGINRigelipcspaLKQSKNMI---LDQAFKYITELKRQNDELLLNGGnn 83
Cdd:COG1340     42 AEKRDELNAQVKELREeaqelREKRDELNEKVKE----------LKEERDELnekLNELREELDELRKELAELNKAGG-- 109

                           90
                   ....*....|....*....
gi 1034631754   84 eqaeEIKKLRKQLEEIQKE 102
Cdd:COG1340    110 ----SIDKLRKEIERLEWR 124

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in USF/MITF family; The USF (upstream stimulatory factor)/MITF (microphthalmia-associated transcription factor) family includes two bHLHzip transcription factor subfamilies. USFs are ubiquitously expressed and key regulators of a wide number of gene regulation networks, including the stress and immune responses, cell cycle and proliferation, lipid and glucid metabolism. USFs recruit chromatin remodeling enzymes and interact with co-activators and the members of the transcription pre-initiation complex. USFs interact with high affinity to E-box regulatory elements. The MITF (also known as microphthalmia-TFE, or MiT) subfamily comprises four genes in mammals (MITF, TFE3, TFEB, and TFEC); each gene has different functions. MITF is involved in neural crest melanocytes development as well as the pigmented retinal epithelium. TFEB is required for vascularization of the mouse placenta. TFE3 is involved in B cell function. TFEC regulates gene expression in macrophages. The MITF subfamily proteins can form homodimers or heterodimers with each other but not with other bHLH or bHLHzip proteins.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034631754   22 THNAVERHRKKKINAGINRIGELIPCSP----ALKQSKNMILDQAFKYITELKRQNDE 75
Cdd:cd11387      1 SHNAVERRRRDNINEKIQELGSLVPPSRletkDLKPNKGSILSKAVEYIRELQNQNQE 58

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in upstream stimulatory factors, USF1, USF2 and similar proteins; Upstream stimulatory factor 1 and 2 (USF-1 and USF-2) are members of bHLHzip transcription factor family. USFs are ubiquitously expressed and key regulators of a wide number of gene regulation networks, including the stress and immune responses, cell cycle and proliferation, lipid and glucid metabolism. USFs recruit chromatin remodeling enzymes and interact with co-activators and the members of the transcription pre-initiation complex. USFs interact with high affinity to E-box regulatory elements.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034631754   22 THNAVERHRKKKINAGINRIGELIP-CSPA---LKQSKNMILDQAFKYITELKRQNDE 75
Cdd:cd11396      1 THNEVERRRRDKINNWIVKLAKIVPdCEKDnskQGQSKGGILSKACDYIQELRSQNER 58

helix loop helix domain;

                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1034631754    24 NAVERHRKKKINAGINRIGELIPCSPA-LKQSKNMILDQAFKYITELKRQNDE 75
Cdd:smart00353    1 NARERRRRRKINEAFDELRSLLPTLPKnKKLSKAEILRLAIEYIKSLQEELQK 53

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in upstream stimulatory factor 1 (USF1) and similar proteins; USF1, also termed Class B basic helix-loop-helix protein 11 (bHLHb11), or major late transcription factor 1, is a bHLHzip transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. It is ubiquitously expressed and involved in the transcription activation of various functional genes implicated in lipid and glucose metabolism, stress response, immune response, cell cycle control and tumour suppression. USF-1 recruits chromatin remodeling enzymes and interact with co-activators and the members of the transcription pre-initiation complex. Genetic polymorphisms of USF1 are associated with some metabolic and cardiovascular diseases, like diabetes, atherosclerosis, coronary artery calcifications and familial combined hyperlipidaemia (FCHL).

                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034631754   17 KKNRETHNAVERHRKKKINAGINRIGELIP-CS---PALKQSKNMILDQAFKYITELKRQN 73
Cdd:cd18924      3 EKRRAQHNEVERRRRDKINNWIVQLSKIIPdCSmesTKSGQSKGGILSKACDYIQELRQSN 63

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein (SREBP) family; The SREBP family includes SREBP1 and SREBP2, which are bHLHzip transcriptional activator of genes encoding proteins essential for cholesterol biosynthesis/uptake and fatty acid biosynthesis. SREBP1 and SREBP2 are principally found in the liver and in adipocytes and made up of an N-terminal transcription factor portion (composed of an activation domain, a bHLHzip domain, and a nuclear localization signal), a hydrophobic region containing two membrane spanning regions, and a C-terminal regulatory segment. They recognize a symmetric sterol regulatory element (TCACNCCAC) instead of E-box.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   14 QHRKKNRETHNAVERHRKKKINagiNRIGEL--IPCSPALKQSKNMILDQAFKYITELKRQNDELLlnggnneqaEEIKK 91
Cdd:cd11394      1 PPKVEKRSAHNAIEKRYRSSIN---DRIIELkdLVVGPDAKMNKSAVLRKAIDYIRYLQKVNQKLK---------QENMA 68

                   ....*
gi 1034631754   92 LRKQL 96
Cdd:cd11394     69 LKKAL 73

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in microphthalmia-associated transcription factor (MITF) and similar proteins; MITF, also termed Class E basic helix-loop-helix protein 32 (bHLHe32), is a bHLHzip transcription factor that is involved in neural crest melanocytes development as well as the pigmented retinal epithelium. It regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. It binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR).

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754    6 ENETPTKKQHRKKnRETHNAVERHRKKKINAGINRIGELIPCS--PALKQSKNMILDQAFKYITELKRQndelllnggnN 83
Cdd:cd18926      1 ESEARALAKERQK-KDNHNLIERRRRFNINDRIKELGTLIPKSndPDMRWNKGTILKASVDYIRKLQRE----------Q 69

                           90
                   ....*....|....*...
gi 1034631754   84 EQAEEIKKLRKQLEEIQK 101
Cdd:cd18926     70 QRAKELENRQKKLEHANR 87

basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana genes coding transcription factors and similar proteins; bHLH proteins are the second largest class of plant transcription factors that regulate transcription of genes that are involve in many essential physiological and developmental process. bHLH proteins are transcriptional regulators that are found in organisms from yeast to humans. The Arabidopsis bHLH proteins that have been characterized so far have roles in regulation of fruit dehiscence, cell development (carpel, anther and epidermal), phytochrome signaling, flavonoid biosynthesis, hormone signaling and stress responses.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1034631754   23 HNAVERHRKKKINAGINRIGELIPcsPALKQSKNMILDQAFKYITELKRQNDEL 76
Cdd:cd11393      1 HSIAERKRREKINERIRALRSLVP--NGGKTDKASILDEAIEYIKFLQEQVKVL 52

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in upstream stimulatory factor 2 (USF2) and similar proteins; USF2, also termed Class B basic helix-loop-helix protein 12 (bHLHb12), or major late transcription factor 2, or FOS-interacting protein (FIP), or upstream transcription factor 2, is a bHLHzip transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   17 KKNRETHNAVERHRKKKINAGINRIGELIP-C---SPALKQSKNMILDQAFKYITELKRQNDELllnggnNEQAEEIKKL 92
Cdd:cd18923      6 ERRRAQHNEVERRRRDKINNWIVQLSKIIPdCntdNSKTGASKGGILSKACDYIRELRQTNQRM------QETYKEAERL 79

                   .
gi 1034631754   93 R 93
Cdd:cd18923     80 Q 80

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein (SREBP) family and similar proteins; The SREBP family includes SREBP1 and SREBP2, which are bHLHzip transcriptional activator of genes encoding proteins essential for cholesterol biosynthesis/uptake and fatty acid biosynthesis. SREBP1 and SREBP2 are principally found in the liver and in adipocytes and made up of an N-terminal transcription factor portion (composed of an activation domain, a bHLHzip domain, and a nuclear localization signal), a hydrophobic region containing two membrane spanning regions, and a C-terminal regulatory segment. They recognize a symmetric sterol regulatory element (TCACNCCAC) instead of E-box. The family also includes Saccharomyces cerevisiae transcription factor HMS1 (also termed high-copy MEP suppressor protein 1) and serine-rich protein TYE7. HMS1 is a putative bHLHzip transcription factor involved in exit from mitosis and pseudohyphal differentiation. TYE7, also termed basic-helix-loop-helix protein SGC1, is a putative bHLHzip transcription activator required for Ty1-mediated glycolytic gene expression. TYE7 N-terminal is extremely rich in serine residues. It binds DNA on E-box motifs, 5'-CANNTG-3'. TYE7 is not essential for growth.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   23 HNAVERHRKKKINAGINRIGELIP--CSPAL--------------KQSKNMILDQAFKYITELKRQNDELllnggnneqA 86
Cdd:cd11395      7 HNAIEKRYRSNLNTKIERLRDAIPslRSPEGksddgglgglapttKLSKATILTKAIEYIRHLEQENERL---------E 77

                           90
                   ....*....|
gi 1034631754   87 EEIKKLRKQL 96
Cdd:cd11395     78 EENEELRQQV 87

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-binding protein Mnt and similar proteins; Mnt, also termed Class D basic helix-loop-helix protein 3 (bHLHd3), or Myc antagonist MNT, or protein ROX, is a bHLHZip transcriptional repressor that binds DNA as a heterodimer with MAX. It binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'. Mnt has an important role as an antagonist and regulator of Myc activities and it is a potential tumor suppressor. Mnt is ubiquitously expressed. Mnt-deficient mice shown to exhibit early postnatal lethality.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   18 KNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLlnggnneqaEEIKKLRKQLE 97
Cdd:cd11402      1 GTREVHNKLEKNRRAHLKECFETLKRQIPNLDDKKTSNLNILRSALRYIQILKRKEKEYE---------HEMERLAREKI 71

                   ....
gi 1034631754   98 EIQK 101
Cdd:cd11402     72 ALQQ 75

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in MLX-interacting protein (MLXIP), MLX-interacting protein-like (MLXIPL) and similar proteins; The family includes MLXIP and MLXIPL. MLXIP, also termed Class E basic helix-loop-helix protein 36 (bHLHe36), or transcriptional activator MondoA, is a bHLHZip transcriptional activator that binds DNA as a heterodimer with Mlx. It binds to the canonical E box sequence 5'-CACGTG-3' and plays a role in transcriptional activation of glycolytic target genes. MLXIP is most highly expressed in skeletal muscle and functions as an indirect glucose sensor, by sensing glucose 6-phosphate and shuttling between the nucleus and the cytoplasm. MLXIPL, also termed carbohydrate-responsive element-binding protein (ChREBP), or Class D basic helix-loop-helix protein 14 (bHLHd14), or MLX interactor, or WS basic-helix-loop-helix leucine zipper protein (WS-bHLH), or Williams-Beuren syndrome chromosomal region 14 protein (WBSCR14), is a bHLHZip transcriptional factor integral to the regulation of glycolysis and lipogenesis in the liver. It forms heterodimers with the bHLHZip protein Mlx to bind the DNA sequence 5'-CACGTG-3'.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   19 NRETHNAVERHRKKKINAGINRIGELIPCS---PALKQSKNMILDQAFKYITELKRQNDELLlnggnneqaEEIKKLRKQ 95
Cdd:cd11405      3 RRLSHISAEQKRRFNIKSGFDTLQSLIPSLgqnPNQKVSKAAMLQKAAEYIKSLKRERQQMQ---------EEAEQLRQE 73

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in sterol regulatory element-binding protein 1 (SREBP1) and similar proteins; SREBP1, also termed Class D basic helix-loop-helix protein 1 (bHLHd1), or sterol regulatory element-binding transcription factor 1 (SREBF1), is a member of a family of bHLHzip transcription factors that recognize sterol regulatory element 1 (SRE-1). It acts as a transcriptional activator required for lipid homeostasis. It may control transcription of the low-density lipoprotein receptor gene as well as the fatty acid. SREBP1 has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').

                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034631754   14 QHRKKNRETHNAVERHRKKKINAGINRIGELIPCSPAlKQSKNMILDQAFKYITELKRQNDEL 76
Cdd:cd18921      1 PSKGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEA-KLNKSAVLRKAIDYIRFLQQSNQKL 62

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Schizosaccharomyces pombe ESC1 (spESC1) and similar proteins; spESC1 is a bHLHzip protein with homology to human MyoD and Myf-5 myogenic differentiation inducers. It is involved in the sexual differentiation process.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034631754   20 RETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDEL 76
Cdd:cd19690      1 RVSHKLAERKRRKEMKELFEDLRDALPQERGTKASKWEILTKAISYIQQLKRHIREL 57

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Max-like protein X (Mlx) family; Mlx, also termed Class D basic helix-loop-helix protein 13 (bHLHd13), or Max-like bHLHZip protein, or protein BigMax, or transcription factor-like protein 4, is a Max-like bHLHZip transcription regulator that interacts with the Max network of transcription factors. It forms a sequence-specific DNA-binding protein complex with some member of Mad family (Mad1 and Mad4) and Mondo family but not the Myc family and bind the E-box DNA to control transcription. The family also includes Saccharomyces cerevisiae INO4, which is a bHLH transcriptional activator of phospholipid synthetic genes (such as INO1, CHO1/PSS, CHO2/PEM1, OPI3/PEM2, etc.). It is required for de-repression of phospholipid biosynthetic gene expression in response to inositol deprivation in yeast.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   19 NRETHNAVERHRKKKINAGINRIGELIP-CSPAlKQSKNMILDQAFKYITELKrqndelllnggnneqaEEIKKLRKQLE 97
Cdd:cd11404      2 RRLNHVRSEKKRRELIKKGYDELCALVPgLDPQ-KRTKADILQKAADWIQELK----------------EENEKLEEQLD 64

                   .
gi 1034631754   98 E 98
Cdd:cd11404     65 E 65

basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor EB (TFEB) and similar proteins; TFEB, also termed Class E basic helix-loop-helix protein 35 (bHLHe35), is a bHLHzip transcription factor that is required for vascularization of the mouse placenta. It specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Its efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF.

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754    6 ENETPTKKQHRKKNretHNAVERHRKKKINAGINRIGELIPCSPAL--KQSKNMILDQAFKYItelKRQNDELllnggnn 83
Cdd:cd18927      1 EARALAKERQKKDN---HNLIERRRRFNINDRIKELGTLIPKTNDLdvRWNKGTILKASVDYI---KRMQKDL------- 67

                           90
                   ....*....|....*....
gi 1034631754   84 EQAEEIKKLRKQLEEIQKE 102
Cdd:cd18927     68 QRSRELENHSRRLEMTNKQ 86

basic helix-loop-helix (bHLH) domain found in the spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein (SOHLH) family and similar proteins; The SOHLH family includes two bHLH transcription factors, SOHLH1 and SOHLH2. They are specifically in spermatogonia and oocytes and essential for early spermatogonial and oocyte differentiation. The family also includes transcription factor-like 5 protein (TCFL5) and similar proteins. TCFL5, also termed Cha transcription factor, or HPV-16 E2-binding protein 1 (E2BP-1), is a bHLH transcription factor that plays a crucial role in spermatogenesis. It regulates cell proliferation or differentiation of cells through binding to a specific DNA sequence like other bHLH molecules.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034631754   18 KNRETHNAVERHRKKKINAGINRIGELIP-CSPalKQSKNMILDQAFKYITELKRQ 72
Cdd:cd19683      1 KSRERHNAKERQRRERIKIACDQLRKLVPgCSR--KTDKATVFEFTVAYIKFLREK 54

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034631754   12 KKQHRKKNRETHNAVE-----RHRKKKINAGINRigelipcspaLKQSKNMI---LDQAFKYITELKRQNDELLLNGGnn 83
Cdd:COG1340     42 AEKRDELNAQVKELREeaqelREKRDELNEKVKE----------LKEERDELnekLNELREELDELRKELAELNKAGG-- 109

                           90
                   ....*....|....*....
gi 1034631754   84 eqaeEIKKLRKQLEEIQKE 102
Cdd:COG1340    110 ----SIDKLRKEIERLEWR 124

basic helix-loop-helix (bHLH) domain found in Arabidopsis thaliana protein FAMA and similar proteins; The family includes several bHLH transcription factors from Arabidopsis thaliana, such as FAMA, MUTE and SPEECHLESS, which work together to regulate the sequential cell fate specification during stomatal development and differentiation. FAMA, also termed AtbHLH97, or EN 14, is a transcription activator required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. It mediates the formation of stomata. MUTE, also termed AtbHLH45, or EN 20, is required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. It promotes the conversion of the leaf epidermis into stomata. SPEECHLESS, also termed AtbHLH98, or EN 19, is required for the initiation and the formation of stomata, by promoting the first asymmetric cell divisions. FAMA, MUTE and SPEECHLESS form heterodimers with SCREAM/ICE1 and SCRM2 to regulate transcription of genes during stomatal development.

                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034631754   22 THNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELkrqndELLLnggnneQAEEIKKLRKQLEEI 99
Cdd:cd11448      2 THIAVERNRRKQMNEHLNVLRSLMPGSYIQRGDQASIVGGAIEFVKEL-----EQLL------QSLEAQKRRRTLNES 68

basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator (ARNT) family; The ARNT family of bHLH-PAS transcription regulators includes ARNT, ARNT-like proteins (ARNTL and ARNTL2), and Drosophila melanogaster protein cycle. They act as the heterodimeric partner for bHLH-PAS proteins such as aryl hydrocarbon receptor (AhR), hypoxia-inducible factor (HIF), and single-minded (SIM). These bHLH-PAS transcription complexes are involved in transcriptional responses to xenobiotic, hypoxia, and developmental pathways. Heterodimerization of bHLH-PAS proteins with ARNT is mediated by contacts between both the bHLH and the tandem PAS domains. ARNT use bHLH and/or PAS domains to interact with several transcriptional coactivators. It is required for activity of the aryl hydrocarbon (dioxin) receptor. ARNTL, also termed Basic-helix-loop-helix-PAS protein MOP3, or brain and muscle ARNT-like 1 (BMAL1), or Class E basic helix-loop-helix protein 5 (bHLHe5), or member of PAS protein 3, or PAS domain-containing protein 3 (PASD3), or bHLH-PAS protein JAP3, is a member of the bHLH-PAS transcription factor family that forms heterodimers with another bHLH-PAS protein, CLOCK (circadian locomotor output cycle kaput), which regulates circadian rhythm. ARNTL-CLOCK heterodimer complex activates transcription from E-box (CANNTG) elements found in the promoter of circadian responsive genes. ARNTL is highly homologous to ARNT. ARNTL2, also termed Basic-helix-loop-helix-PAS protein MOP9, or brain and muscle ARNT-like 2 (BMAL2), or CYCLE-like factor (CLIF), or Class E basic helix-loop-helix protein 6 (bHLHe6), or member of PAS protein 9, or PAS domain-containing protein 9 (PASD9), is a neuronal bHLH-PAS transcriptional factor, regulating cell cycle progression and preventing cell death, whose sustained expression might ensure brain neuron survival. It also plays important roles in tumor angiogenesis. Protein cycle, also termed brain and muscle ARNT-like 1 (BMAL1), or MOP3, is a putative bHLH-PAS transcription factor involved in the generation of biological rhythms in Drosophila. It activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (5'-CACGTG-3') present in their promoters.

                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034631754   20 RETHNAVERHRKKKINAGINRIGELIP-CSP-ALKQSKNMILDQAFKYITELKRQND 74
Cdd:cd11437      2 RSNHSEIEKRRRDKMNAYIQELSALVPaCNAmSRKLDKLTVLRMAVQHLKSLRGTGS 58