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Conserved domains on  [gi|1034663651|ref|XP_016869723|]
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A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform X5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ADAM_CR_3 super family cl41950
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
111-225 5.81e-74

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


The actual alignment was detected with superfamily member pfam19236:

Pssm-ID: 437068  Cd Length: 115  Bit Score: 239.61  E-value: 5.81e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  111 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 190
Cdd:pfam19236    1 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 80
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1034663651  191 LCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 225
Cdd:pfam19236   81 LCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
ADAM_spacer1 pfam05986
ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of ...
227-350 9.14e-51

ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of metalloproteinases.


:

Pssm-ID: 428708  Cd Length: 115  Bit Score: 174.31  E-value: 9.14e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  227 PRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVR-IGGRYVVAGKMSISPNTTYPSLLEDGrVEYRValted 305
Cdd:pfam05986    1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKnVQGKYILNGKGSISLNPTYPSLLGTV-LEYRR----- 74
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1034663651  306 RLPRLEEIRIWGPLQEDADIQVYRRYGEeygnLTRPDITFTYFQP 350
Cdd:pfam05986   75 SLPALEELHAPGPTQEDLEIQVLRQYGK----GTNPGITYEYFIP 115
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
57-109 5.16e-14

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


:

Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 67.23  E-value: 5.16e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1034663651    57 WSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACE 109
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGEDVETRACNEQPCP 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
746-800 2.74e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.74e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034663651  746 WHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPC 800
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKPPETQSCNLKPC 55
ADAM_CR_2 super family cl39281
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
1-41 8.17e-08

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


The actual alignment was detected with superfamily member pfam17771:

Pssm-ID: 436031  Cd Length: 70  Bit Score: 50.06  E-value: 8.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1034663651    1 MCQALSChTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRC 41
Cdd:pfam17771   30 VCSKLWC-SNPNGSSKCTTKGLPAADGTPCGNGKWCINGKC 69
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
632-682 9.75e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 49.37  E-value: 9.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651  632 CSVSCGRGVVRRILYCARAHgeddGEEILLDTQCQGLPRPEPQEACSLEPC 682
Cdd:pfam19030    9 CSVTCGGGVQTRLVQCVQKL----GGSLVPDSQCSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
416-474 4.77e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 47.45  E-value: 4.77e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034663651  416 WAVGDFGPCSASCGGGLRERPVRCVEAQGslLKTLPPARCRAGAQQPAValETCNPQPC 474
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLG--GSLVPDSQCSAQKKPPET--QSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
686-742 2.08e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


:

Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 45.91  E-value: 2.08e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034663651  686 WKVMSLGPCSASCGLGTARRSVACVQLDqGQDVEVDEaACAALVRPEASVPCLIADC 742
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKL-GGSLVPDS-QCSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
572-621 1.66e-03

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 37.43  E-value: 1.66e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034663651  572 GSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPgSRREVCQAVPC 621
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKP-PETQSCNLKPC 55
 
Name Accession Description Interval E-value
ADAM_CR_3 pfam19236
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
111-225 5.81e-74

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 239.61  E-value: 5.81e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  111 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 190
Cdd:pfam19236    1 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 80
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1034663651  191 LCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 225
Cdd:pfam19236   81 LCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
ADAM_spacer1 pfam05986
ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of ...
227-350 9.14e-51

ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of metalloproteinases.


Pssm-ID: 428708  Cd Length: 115  Bit Score: 174.31  E-value: 9.14e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  227 PRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVR-IGGRYVVAGKMSISPNTTYPSLLEDGrVEYRValted 305
Cdd:pfam05986    1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKnVQGKYILNGKGSISLNPTYPSLLGTV-LEYRR----- 74
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1034663651  306 RLPRLEEIRIWGPLQEDADIQVYRRYGEeygnLTRPDITFTYFQP 350
Cdd:pfam05986   75 SLPALEELHAPGPTQEDLEIQVLRQYGK----GTNPGITYEYFIP 115
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
57-109 5.16e-14

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 67.23  E-value: 5.16e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1034663651    57 WSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACE 109
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGEDVETRACNEQPCP 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
746-800 2.74e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.74e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034663651  746 WHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPC 800
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKPPETQSCNLKPC 55
TSP_1 pfam00090
Thrombospondin type 1 domain;
58-108 4.31e-08

Thrombospondin type 1 domain;


Pssm-ID: 395043 [Multi-domain]  Cd Length: 49  Bit Score: 50.49  E-value: 4.31e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651   58 SSWGPRSPCSRSCGGGVVTRRRQCNNPRPafGGRACVGADLQAEMCNTQAC 108
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGIQVRQRTCKSPKP--GGEPCTGDDIETQACKMDKC 49
ADAM_CR_2 pfam17771
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
1-41 8.17e-08

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


Pssm-ID: 436031  Cd Length: 70  Bit Score: 50.06  E-value: 8.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1034663651    1 MCQALSChTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRC 41
Cdd:pfam17771   30 VCSKLWC-SNPNGSSKCTTKGLPAADGTPCGNGKWCINGKC 69
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
632-682 9.75e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 49.37  E-value: 9.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651  632 CSVSCGRGVVRRILYCARAHgeddGEEILLDTQCQGLPRPEPQEACSLEPC 682
Cdd:pfam19030    9 CSVTCGGGVQTRLVQCVQKL----GGSLVPDSQCSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
416-474 4.77e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 47.45  E-value: 4.77e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034663651  416 WAVGDFGPCSASCGGGLRERPVRCVEAQGslLKTLPPARCRAGAQQPAValETCNPQPC 474
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLG--GSLVPDSQCSAQKKPPET--QSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
686-742 2.08e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 45.91  E-value: 2.08e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034663651  686 WKVMSLGPCSASCGLGTARRSVACVQLDqGQDVEVDEaACAALVRPEASVPCLIADC 742
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKL-GGSLVPDS-QCSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
572-621 1.66e-03

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 37.43  E-value: 1.66e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034663651  572 GSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPgSRREVCQAVPC 621
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKP-PETQSCNLKPC 55
 
Name Accession Description Interval E-value
ADAM_CR_3 pfam19236
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
111-225 5.81e-74

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


Pssm-ID: 437068  Cd Length: 115  Bit Score: 239.61  E-value: 5.81e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  111 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 190
Cdd:pfam19236    1 TQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS 80
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1034663651  191 LCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 225
Cdd:pfam19236   81 LCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
ADAM_spacer1 pfam05986
ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of ...
227-350 9.14e-51

ADAM-TS Spacer 1; This family represents the Spacer-1 region from the ADAM-TS family of metalloproteinases.


Pssm-ID: 428708  Cd Length: 115  Bit Score: 174.31  E-value: 9.14e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034663651  227 PRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVR-IGGRYVVAGKMSISPNTTYPSLLEDGrVEYRValted 305
Cdd:pfam05986    1 TVSGSFTEGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKnVQGKYILNGKGSISLNPTYPSLLGTV-LEYRR----- 74
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1034663651  306 RLPRLEEIRIWGPLQEDADIQVYRRYGEeygnLTRPDITFTYFQP 350
Cdd:pfam05986   75 SLPALEELHAPGPTQEDLEIQVLRQYGK----GTNPGITYEYFIP 115
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
57-109 5.16e-14

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 67.23  E-value: 5.16e-14
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|...
gi 1034663651    57 WSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACE 109
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQNGGGPCTGEDVETRACNEQPCP 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
746-800 2.74e-10

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 56.69  E-value: 2.74e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1034663651  746 WHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPC 800
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKPPETQSCNLKPC 55
TSP_1 pfam00090
Thrombospondin type 1 domain;
58-108 4.31e-08

Thrombospondin type 1 domain;


Pssm-ID: 395043 [Multi-domain]  Cd Length: 49  Bit Score: 50.49  E-value: 4.31e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651   58 SSWGPRSPCSRSCGGGVVTRRRQCNNPRPafGGRACVGADLQAEMCNTQAC 108
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGIQVRQRTCKSPKP--GGEPCTGDDIETQACKMDKC 49
ADAM_CR_2 pfam17771
ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like ...
1-41 8.17e-08

ADAM cysteine-rich domain; This cysteine rich domain is found in a variety of ADAM like peptidases. This domain is distantly related to pfam08516.


Pssm-ID: 436031  Cd Length: 70  Bit Score: 50.06  E-value: 8.17e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 1034663651    1 MCQALSChTDPLDQSSCSRLLVPLLDGTECGVEKWCSKGRC 41
Cdd:pfam17771   30 VCSKLWC-SNPNGSSKCTTKGLPAADGTPCGNGKWCINGKC 69
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
632-682 9.75e-08

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 49.37  E-value: 9.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651  632 CSVSCGRGVVRRILYCARAHgeddGEEILLDTQCQGLPRPEPQEACSLEPC 682
Cdd:pfam19030    9 CSVTCGGGVQTRLVQCVQKL----GGSLVPDSQCSAQKKPPETQSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
416-474 4.77e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 47.45  E-value: 4.77e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034663651  416 WAVGDFGPCSASCGGGLRERPVRCVEAQGslLKTLPPARCRAGAQQPAValETCNPQPC 474
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKLG--GSLVPDSQCSAQKKPPET--QSCNLKPC 55
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
686-742 2.08e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 45.91  E-value: 2.08e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1034663651  686 WKVMSLGPCSASCGLGTARRSVACVQLDqGQDVEVDEaACAALVRPEASVPCLIADC 742
Cdd:pfam19030    1 WVAGPWGECSVTCGGGVQTRLVQCVQKL-GGSLVPDS-QCSAQKKPPETQSCNLKPC 55
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
58-108 3.10e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 436909 [Multi-domain]  Cd Length: 52  Bit Score: 44.96  E-value: 3.10e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1034663651   58 SSWGPRSPCSRSCGGGVVTRRRQCNNPrPAFGGRACvGADLQAEMCNTQAC 108
Cdd:pfam19028    4 SEWSEWSECSKTCGGGVQTRTRTIIVE-PQNGGRPC-PELLERRPCNLPPC 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
572-621 1.66e-03

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 408800 [Multi-domain]  Cd Length: 55  Bit Score: 37.43  E-value: 1.66e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1034663651  572 GSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPgSRREVCQAVPC 621
Cdd:pfam19030    7 GECSVTCGGGVQTRLVQCVQKLGGSLVPDSQCSAQKKP-PETQSCNLKPC 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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